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H. S. H. Boroojeni et al.

Rapid Prototyping Models inOral
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andMaxillofacial Surgery: History,
Definition, andIndications
SadraMohaghegh, SaharBaniameri, andArashKhojasteh
1 Introduction
In the age of virtual imaging, due to the emergence of recent advances in technology
and digital solutions, diagnosis and treatment planning in the eld of maxillofacial
surgery has changed and led to a change from a conventional two-dimensional (2D)
technique to an advanced three-dimensional (3D) method, which is known as “rapid
prototyping” [1, 2]. Rapid prototyping (RP) is one of the recent advances in modern
surgery that creates a three-dimensional model with a layer-by-layer process of adding based on 3D computer-aided design (CAD) data. This technology is also referred
to as “layer production,” “solid free form production,” or “3D printing” [3, 4]. This
concept was rst introduced in the 1980s in engineering to build solid models of
computed and day-to-day les [5]. Since then, exciting opportunities in various
aspects of maxillofacial surgery, such as orthodontics, prosthetics, oral surgery, and
implantology, have provided [6]. In maxillofacial surgery, RP models can be used
for treatment planning and simulation.
Medical models or bio models represent three-dimensional medical imaging
such as computed tomography (CT) scans, cone-beam computed tomography
(CBCT), or magnetic resonance imaging (MRI) scans [7]. High-quality volumetric
three-dimensional image data of the required anatomical structure can be obtained.
S. Mohaghegh · S. Baniameri
Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti
University of Medical Sciences, Tehran, Iran
A. Khojasteh (*)
Dental Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of
Medical Sciences, Tehran, Iran
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023
A. Khojasteh et al. (eds.), Emerging Technologies in Oral and Maxillofacial
Surgery, https://doi.org/10.1007/978-981-19-8602-4_5
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S. Mohaghegh et al.
Digital Imaging and Communication in Medicine (DICOM) format les are created
and converted to Standard Tessellation Language (STL) format les using computeraided design (CAD) software. These les are then uploaded to a 3D printer, and a
rapid prototype (RP) model is created, guided by the model’s quality assurance and
dimensional accuracy [8, 9].
These models can be fabricated using various additive manufacturing methods,
including material extrusion approaches such as fused deposition molding (FDM),
vat polymerization (i.e., stereolithography), powder bed fusion (e.g., selective laser
sintering and selective laser melting), and binder or material jetting (Fig.1) [10–12].
The features expected for each surgical indication specify the type of utilized material and fabrication method. Figure2 compared the advantages and disadvantages of
different methods based on their possible application in oral and maxillofacial surgery [13].
RP models can enhance the surgical procedure’s precision, decrease the physician’s stress, and comprehensively visualize the defects. Besides, using these models in education can enhance the graduates’ practical knowledge, leading to
high-quality health services [14, 15]. Setting aside the advantages of using RP models, nowadays, VSP enables accurate analysis of the surgical site and the treatment
plan. However, it must be considered that using VSP is more complicated than RP
models in some instances. Therefore, virtual technologies do not entirely replace
RP models [16].
abc
de
Fig. 1 Schematic drawing of additive manufacturing methods that can be used to fabricate rapid
prototyping models [13]. (a) Powder bed fusion (b) Vat photopolymerization (c) Material extrusion (d) Binder jetting (e) Material jetting

Rapid Prototyping Models in Oral and Maxillofacial Surgery: History, Denition…
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Fig. 2 Briey describe the pros and cons of using each method to fabricate rapid prototyping
models for different oral and maxillofacial surgery procedures. Red color refers to an improper and
green to the optimal situation. The yellow color means the intermediate status. ME material extrusion, VATP vat polymerization, PBF powder bed fusion, BJ binder jetting, MJ material jetting [13]
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2 Treatment Planning
Treatment planning is the most common indication of RP models. Indeed, the
importance of accuracy and result predictability in maxillofacial treatments makes
surgeons analyze each step through printed models and evaluate the outcome. Using
RP models can decrease the intervention time, reducing posttreatment complications, such as excessive bleeding, morbidity, and infection [17, 18].
Application of RP models in OMFS can be categorized into two main domains:
dental procedures, such as implant dentistry or sinus augmentation, and extraoral
procedures, such as management of maxillomandibular defects [19], TMJ disorders
[20], orbital wall reconstruction [21], and orthognathic surgery [13]. More specically, RP models benet all four aspects of maxillofacial reconstruction. Figures3
and 4 show the application of models in the functional bone regeneration procedure
to reconstruct the orbital wall and posterior mandible. Besides, these models can
also be applied in bone contouring and in situ bone regeneration.
In implant treatment planning, one option is fabricating a master cast through
acquired STL data and analyzing the surgical procedure on the 3D printed cast.
Using additive manufacturing may reduce the possible distortions related to traditional methods, demand much easier laboratory procedures, and decrease the
costs [22].
Among different extraoral surgeries, RP models are most commonly used in
patients with malignancies [16, 23]. In detail, RP models can be used in both reconstruction (Fig.3) and ablation phases. The application of free grafts is one of the
treatment options for reconstructing mandibles with large defects. Using

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S. Mohaghegh et al.
c
d
Fig. 3 shows the use of RP in the reconstruction of the orbital region. (a) Data extracted from CT
scan. (b) Designing patient-specic implant. (c) Fabrication of the RP models illustrating the
defects anatomy on the patient’s skull. (d) Patient-specic implant matching the defected area
patient- specic RP models, the grafted bone can be trimmed accurately ex vivo.
This type of RP model is named “3D printed xation tray” [24]. Considering the
importance of precision in this procedure, sintering-based methods are recommended for model fabrication.
In the case of using reconstruction plates, presurgical bending can be performed based on the fabricated RP, as shown in Fig.5. In the resection phase, the
tumor’s borders can be colored on the models, enabling the surgeon to analyze
the dimensions and location of the tumor. However, the more accurate approach
is to fabricate hybrid prototyping models. In these types of RP models, the tumor
part can be fabricated with different materials, and the vital structures around the

Rapid Prototyping Models in Oral and Maxillofacial Surgery: History, Denition…
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a b
c
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Fig. 4 shows the process of designing and manufacturing a patient-specic implant in the mandible. (a) Designing patient-specic implants using CT scan data. (b) Printed model of patient
mandible and the degradable implant. (c) Implants are placed in the defected area during surgery.
(Figure courtesy of Dr. Arash Khojasteh)
tumor can be emphasized using different colors or materials. Hence, hybrid models can better illustrate the relationship between tumor, intact bone, and surrounding tissue [25].
Photosensitive resins, polyamide, poly lactic acid (PLA), acrylonitrile butadiene
styrene (ABS), and composite powders are the materials that can be used for fabricating treatment planning models [26]. Although there is no evidence regarding the
optimal material and fabrication method, the following points have to be considered
regarding each of the mentioned materials: photosensitive resin models are fabricated through sintering-based methods and inkjet printing [27]. However, more
accurate models can be made through the latter method. ABS and PLA models are
fabricated using extrusion-based printing methods, which have less accuracy than
the abovementioned techniques. Binders can also be used to fabricate models made
up of uncurable powders such as composites. Nevertheless, this method has less

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Fig. 5 Application of RP in presurgical plate bending. (a) Mandibular rapid prototype model
fabricated by FDM. (b) Presurgical bending of reconstruction plate on the fabricated RP model.
(Figure courtesy of Dr. Arash Khojasteh)
S. Mohaghegh et al.
accuracy than sintering-based and low-temperature extrusion methods. The fabrication costs are the other important factor that must be considered. As Meglioli etal.
[13] mentioned, inkjet printing imposes high costs while extrusion- and sinteringbased methods have more acceptable results.
Different studies showed that the application of RP models can enhance the treatment procedure results [28]. However, it must be considered that there is limited
comparative evidence in this eld.
3 Training andSimulation
Simulating the surgical procedure is the other indication of RP models. Considering
the importance of operation time on the postsurgical complications, performing the
simulation of the surgery before the actual treatment can enhance the post-operation
results. Besides, models can be used to train surgeons for a specic procedure, since
they are more accessible than cadaver and animal models. Therefore, RP models
have been used for training temporal bone surgeries, implant treatments, and maxillary sinus augmentation [16, 29, 30]. CBCT can be helpful in evaluations, but with
3D printed models, physicians can observe the anatomy and simulate the procedure
presurgical.
Moreover, 3D printed models can be helpful in designing aps [31–33]. Besides,
in implant dentistry, due to esthetic expectations and poor bone quality, the anterior
part of the maxilla has always been challenging for dental implants. Guided bone
regeneration (GBR) is a complex procedure, but nowadays, with 3D models, surgeons can be more familiar with the patient’s anatomy before surgery, leading to
less operation time and less tissue manipulation [34–36].
Proper haptic feedback is the main factor that must be considered in simulating
models. In detail, the composition of the models has to provide an elastic modulus,
stiffness, and other mechanical properties as of the natural tissue [13]. Among the
commonly used techniques, inkjet printing, usually performed with photosensitive
resin, can provide models with proper feedback. Fabricating powders with binder

Rapid Prototyping Models in Oral and Maxillofacial Surgery: History, Denition…
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83
provide the same results. However, models with lower haptic feedback quality can
be fabricated through other techniques (extrusion- and sintering-based). ADS, PLA,
and photosensitive resins are used with these techniques [13].
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