Добавил:
Sekretar
kiopkiopkiop18@yandex.ru
t.me/Prokururor I Вовсе не секретарь, но почту проверяю
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз:
Предмет:
Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_917_Библиотеки_им_академика_М_И_Перельмана.pdf
X
- •Preface
- •Acknowledgments
- •Contents
- •Contributors
- •1: SAGES University MASTERS Program: Colorectal Pathway
- •Introduction
- •References
- •Colorectal Surgery Curriculum
- •Facebook™ Groups
- •Conclusion
- •Operative Setup
- •Operating Room Setup
- •Patient Positioning
- •Operative Technique: Surgical Steps
- •Trocar Placement
- •Top-Down Approach
- •Outcomes
- •Conclusions
- •References
- •Operative Setup
- •Operative Technique
- •Port Placement
- •Left/Sigmoid Colectomy
- •Outcomes
- •Conclusions
- •References
- •Operative Setup
- •Operative Technique: Surgical Steps
- •Supramesocolic Approach
- •Inframesocolic Approach
- •Outcomes
- •Conclusions
- •References
- •Bibliography
- •Operative Setup
- •Operative Technique: Surgical Steps
- •Laparoscopic Access
- •Colon Transection
- •Specimen Extraction
- •Anastomosis
- •Fistula Repair
- •Other Steps
- •Outcomes
- •Conclusions
- •References
- •Outcomes
- •Conclusion
- •References
- •Solicit Institutional Support
- •Reviewing Current Data
- •Overcoming Barriers Through Culture Change
- •Conclusions
- •References
- •Conclusion
- •References
- •Preoperative Risk Assessment
- •Special Considerations
- •Immune Suppression
- •Smokers
- •Malnutrition
- •Obesity
- •Renal Impairment
- •Preoperative Stoma Marking
- •Preoperative Patient Education
- •Parenteral Antibiotics
- •Positioning
- •Surgical Time-Out
- •Conclusion
- •References
- •Introduction
- •Preoperative Preparation
- •Laparoscopic Access
- •Special Considerations
- •Complicated Peritoneal Entry
- •Equipment Issues
- •Physiologic Issues
- •Optimizing Laparoscopic Exposure
- •OR Table Positioning
- •Laparoscopic Visualization
- •Splenic Bleeding
- •Organ Injury
- •Small Bowel Injury
- •Ureteral Injury
- •Trocar Site Closure
- •Conclusion
- •References
- •Definitions
- •Central Venous Ligation (CVL)
- •Pathological Outcomes
- •Long-Term Survival
- •Conclusion
- •References
- •12: Unexpected Findings at Appendectomy
- •Inflamed Meckel’s Diverticulum
- •Appendiceal Mass
- •Conclusions
- •References
- •Cecal Diverticulitis
- •Sigmoid Diverticulitis
- •Epiploic Appendagitis
- •Crohn’s Disease
- •Gynecologic Pathology
- •Operative Setup
- •Operative Technique: Surgical Steps, Medial-to-Lateral Approach
- •Outcomes
- •Conclusions
- •References
- •Preoperative Planning
- •Operative Techniques
- •Positioning
- •Trocars Placement
- •Side-to-Side Stapled Anastomosis
- •Side-to-Side Handsewn Anastomosis
- •Side-to-End Stapled Anastomosis
- •Side-to-End Handsewn Anastomosis
- •End-to-Side Handsewn Anastomosis
- •End-to-End Handsewn Anastomosis
- •Operative Time
- •Spillage
- •Alignment/Ergonomics
- •Outcomes
- •Conclusions
- •References
- •Operative Setup
- •da Vinci Xi® Setup (Intuitive Surgical, Sunnyvale, CA, USA)
- •Operative Technique: Surgical Steps
- •Outcomes
- •Conclusions
- •References
- •Operative Setup
- •Complex Crohn’s Disease Resection
- •Crohn’s Fistula
- •Difficult Crohn’s Mesentery
- •Ileocolonic Reconstruction
- •Intracorporeal Anastomosis
- •Extracorporeal Anastomosis
- •Entry
- •Adhesiolysis
- •Thickened Mesentery
- •Anastomotic Problems
- •Postoperative Issues
- •Outcomes
- •Conclusion
- •References
- •Preoperative Optimization
- •Accelerated Recovery Pathway
- •Operative Technique: Surgical Steps
- •Locally Advanced Tumors
- •Outcomes
- •Conclusions
- •References
- •Operative Setup
- •Operative Technique: Surgical Steps
- •Colonic J Pouch
- •Transverse Coloplasty
- •Baker’s Anastomosis
- •Anastomotic Assessment
- •Rectal Stump Blowout
- •Staple Line Bleeding
- •Outcomes
- •Anastomotic Leak
- •Anastomotic Assessment
- •Temporary Fecal Diversion
- •Conclusion
- •References
- •Malignant Diseases
- •Benign Diseases
- •Operative Setup
- •Patient Positioning
- •Room Setup
- •Operative Technique
- •Trocar Placement
- •Si® Robot (Intuitive Surgical, Sunnyvale, CA, USA)
- •Xi® Robot (Intuitive Surgical, Sunnyvale, CA, USA)
- •Si Robot
- •Xi Robot
- •Instrument Insertion
- •Extracorporeal Anastomosis
- •Intracorporeal Anastomosis
- •Instrument Collisions
- •Bleeding
- •Anastomotic Leak
- •Outcomes
- •Conclusions
- •References
- •Operative Technique: Surgical Steps
- •Adhesions
- •Difficult Rectal Stump Dissection
- •Rectal Stump Retraction
- •Outcomes
- •Conclusion
- •References
- •Review Operative Report
- •Review Pathology Report
- •Cross-Sectional Imaging
- •Ureteral Stents
- •Operative Setup
- •Operative Technique: Surgical Steps
- •Outcomes
- •Conclusion
- •References
- •Preoperative Staging
- •Indications and Contraindications
- •Multidisciplinary Management
- •Preoperative Versus Postoperative Chemoradiation
- •Short-Course Radiotherapy
- •Intraoperative Radiation
- •Adjuvant Chemotherapy
- •Total Neoadjuvant Therapy
- •Nonoperative Management
- •Conclusion
- •References
- •Other Equipment/Incisions
- •Splenic Flexure Mobilization
- •Lateral Dissection
- •Pelvic Dissection
- •Outcomes
- •Conclusions
- •References
- •Operative Setup
- •Positioning
- •Port Placement
- •Extraction Site
- •Operative Technique: Surgical Steps
- •Splenic Flexure Release
- •Rectal Mobilization
- •Posterior Dissection
- •Lateral Dissection
- •Anterior Dissection
- •Pelvic Floor Dissection
- •Outcomes
- •Conclusions
- •References
- •Introduction
- •Synchronous Masses/Tumors
- •Meckel’s Diverticulum
- •Peritoneal Carcinomatosis
- •Liver Metastasis
- •Ovarian Mass
- •Malrotation
- •Conclusion
- •References
- •Outcomes
- •Conclusions
- •References
- •Technique
- •Learning Curve
- •Outcomes
- •Conclusions
- •References
- •Operative Strategy
- •Operative Setup
- •Patient Positioning
- •Port Placement
- •Diagnostic Laparoscopy
- •Minimally Invasive Resectional Approach
- •Best Approach
- •Splenic Flexure Mobilization (If Needed)
- •Distal Colon Transection
- •Considerations During Laparoscopic Hartmann’s Procedure
- •Obese Patients
- •Minimally Invasive Non-resectional Approach
- •Laparoscopic Peritoneal Lavage
- •Operative Setup
- •Port Placement
- •Postoperative Management
- •Outcomes
- •Resection
- •Laparoscopic Lavage
- •Conclusions
- •References
- •Outcomes
- •Conclusion
- •References
- •Splenic Flexure Release
- •Colonic Conduit Ischemia
- •Conclusion
- •References
- •Surgeon-Related Factors
- •Bowel Preparation
- •Ureteral Stents
- •Patient Positioning
- •Pneumoperitoneum
- •Laparoscopic Exposure: Trocars
- •Laparoscopic Adhesiolysis

5 Masters Program Colorectal Pathway: Laparoscopic Left Colon Resection…
Standard venous thromboembolism prophylaxis and preoperative intravenous
antibiotics should be administered in accordance with SCIP (Surgical Care
Improvement Project) guidelines [12]. This has been shown to minimize the risk of
surgical site infection. Enhanced recovery programs also call for antinausea prophylaxis to be administered [12]. Currently, alvimopan is not indicated for laparoscopic
surgery, as it has not been clearly shown to improve postoperative outcomes; however, we will give a single dose to patients at high risk of conversion, and this will
continue postoperatively if the patient is converted to open surgery. For more details
on enhanced recovery recommendations, please refer to the chapter on enhanced
recovery protocols in colorectal surgery (Chaps. 7 and 8).
65
Operative Setup
Patients are placed in a modied lithotomy position, ensuring that the legs and arms
are positioned appropriately to avoid nerve injury. The patient’s arms should both be
tucked by their sides, with the use of sleds if needed for larger patients. In order to
overcome the steep Trendelenburg positioning, a bean bag may be placed underneath the patient, the chest may be taped to the table, or anti-sliding padding can be
used. The lithotomy position is important so access to the anus is maintained.
Operative Technique: Surgical Steps
The basics steps of laparoscopic colectomy for CD follow similar principles to
those described in the chapters on laparoscopic left and sigmoid colectomy for
benign (Chap. 3) and malignant disease (Chap. 17). In cases of abscess and stula
with inammatory bowel disease, and similar to some complex diverticular disease,
there are several operative steps that are helpful.
Laparoscopic Access
Many of these cases are re-operative in nature. Even so, we start with a sub- umbilical
cutdown to insert a Hasson balloon port. This commonly is quite straightforward. If
there are adhesions or concerns of adherent intestine, a lateral 5mm visual port is
inserted, away from the area of the pathology. This guides placement of a second
port which allows adhesiolysis and insertion of additional ports as required.
Definition ofAnatomy andPathology andAbscess Management
The procedure starts with a review of the area of pathology. Multiple small bowel
loops may be involved and there may be extensive adhesions. The operation then
starts with lysis of adhesions, separating each loop individually off the phlegmon.

66
A. R. Bhama and C. P. Delaney
In these cases, the entire small bowel will be examined extracorporeally, but if there
are areas of particular concern, they are marked with a laparoscopic 3-0 polyglycolic acid suture. Loops of small bowel that contain stulas are controlled by an
endoloop suture, to minimize intraabdominal leakage and contamination. Generally,
each adherent loop of bowel is separated so that they can be removed through a
small incision for resection or examination.
Once the small bowel loops have been separated, the colon can be evaluated. The
decision of whether the mesentery or bowel is mobilized rst really depends on
what step will facilitate dissection of the diseased segment most safely and effectively. Oftentimes, the best strategy is to start by mobilizing the bowel proximal to
the pathology in order to dene the correct anatomical planes. This will help identify anatomic landmarks and guide the dissection safely toward the diseased segments and associated phlegmons, abscess cavities, and/or stulas. This dissection
will lead next to taking down colovesical, colovaginal stulas, or even left lower
quadrant cutaneous stulas. These are transected with a combination of sharp dissection with scissors and blunt dissection using a Maryland or bowel grasper. For
those who like energy devices for dissection, these are particularly unsuitable in
stula and abscess cases, as the tissues are often so thickened that the energy devices
cannot be closed effectively. When a pericolonic abscess cavity is unroofed, a suction device is immediately positioned into the cavity to aspirate out all pus before it
contaminates the abdomen. The goal at this stage is simply to control and minimize
spillage of purulence. The use of monopolar cautery should be minimized in order
to avoid inadvertent burn injury to the bowel. Sponges can be very helpful to achieve
hemostasis as well as to provide effective bowel retraction. Frequently ovaries, fallopian tubes, or the appendix may be adherent to the inammatory phlegmon or
abscess and must be carefully separated. If the appendix is involved, it is removed
as per routine. Once the pathology and anatomy have been fully dened, the entire
small bowel should be examined for disease, as described above.
Another important consideration is identication of the ureter. Frequently the
ureter may be more medial than expected due to distorted anatomy from the inammatory process. Consider ureteral stents, although these are generally not required
except for cases with a psoas abscess, prior pelvic surgery, or some colovaginal
stulae with a phlegmon involving the pelvic sidewall.
Mobilization andDivision ofMesentery
For the left colon, a low ligation of the inferior mesenteric vessels is adequate unless
there is dysplasia or a concern for cancer. Our preferred approach in cancer is a
medial to lateral approach to the mesentery. This frequently also works well in cases
with inammatory disease. Usually the easiest rst step is to grasp the rectosigmoid
mesentery and elevate it from the retroperitoneum and incise with scissors or cautery parallel to the inferior mesenteric vessels over the sacral promontory. This
allows CO
routine. If there is too much tethering on the mesentery because of a vesical stula,
to distend the presacral space, and the mesentery is mobilized as per
2

5 Masters Program Colorectal Pathway: Laparoscopic Left Colon Resection…
67
this is taken down rst. The left colic vessels may need to be divided to achieve
adequate length for tension-free colorectal anastomosis.
In cases where the abscess is medial, however, a medial approach is fraught with
difculty, and there is frequently too much inammation to visualize any plane.
Rather than transecting the mesentery blindly, we will switch to a lateral to medial
approach. The planes there are often more manageable, even allowing mobilization
as far medial as the ureter and presacral space. If that is not the case, move proximally on the descending colon, and a plane can usually be found. The last option is
a high medial approach, coming between the duodenojejunal exure and the inferior mesenteric vein, which generally allows entry to a clean anatomical plane.
If there is any doubt about an anatomical plane, stay inside the mesenteric fascia.
While this causes a little more bleeding, it is much safer. It is important not to dissect blindly, particularly with an energy device, as these can so effectively stop
bleeding that one may stray outside the correct plane and cause injury to surrounding urinary, vascular, or nerve structures.
Many of these abscesses and stulas involve the left pelvic sidewall. In these
cases, one must carefully combine blunt and sharp dissection techniques, and frequently switch from medial to lateral views, to progress gradually to completely
dissect the mesentery off the abscess wall or pelvic sidewall. The goal is to have
adequately mobilized the left colon, so that the diseased segment can be removed,
with an adequate margin of normal tissue and adequate length for a tension-free
anastomosis. Splenic exure mobilization is almost routinely required in these cases
but division of the inferior mesenteric vein again at the tail of the pancreas is rarely
required. Please refer to specic laparoscopic techniques in Chap. 4 on laparoscopic
splenic exure release.
Colon Transection
Proximal colonic division is generally extracorporeal. The distal transection margin
is critical and may be complex. The most frequent consideration is whether one is
distal to the inammation. Our goal is always to mobilize enough rectum and mesorectum so that we reach visibly and palpably normal tissue. Sometimes a loop of
sigmoid is stuck in the pelvis, and this must be completely mobilized. Sometimes
the upper rectal wall is thickened because of an adjacent abscess, and we generally
mobilize more distally, sometimes below the peritoneal reection until normal
bowel can be identied. If the rectum does not look healthy enough for an anastomosis, it is transected as a Hartmann’s stump and an end colostomy is brought out,
which may subsequently be closed depending on a variety of factors such as pathology, patient status, etc. Indeed, the quality of the distal rectum is usually a predominant determinant of whether an anastomosis will be performed, or a Hartmann’s
stump left for safety. Additional considerations for anastomosis include the extent
and severity of any residual proctitis in the rectal stump. For details on steps to take
during Hartman’s procedures, please refer to the chapter on Key steps to facilitate
minimally invasive Hartmann’s reversal (Chap. 20).

68
A. R. Bhama and C. P. Delaney
Specimen Extraction
In simple cases requiring a sigmoid or left colon resection, a left lower quadrant
muscle splitting incision is made. This is technically straightforward with a low
complication rate. If a diverting stoma is required, the specimen is removed through
that opening, if necessary making a “key-hole” incision to enlarge the opening.
For patients with an enterocolic stula that required dissection of tethered small
bowel loops from an abscess or phlegmon, or with concurrent ileocolic and left
colon disease, a short periumbilical midline incision is used. A wound protector is
critical to prevent contamination by the abscess or stula. This permits sequential
exteriorization of the entire length of the small bowel, which can be examined,
resected, or repaired as appropriate.
Anastomosis
Small bowel anastomoses are performed most frequently using a stapled side-side
functional end-end approach. Left-sided anastomoses are stapled transanally. We
use a 28mm circular stapler to minimize anal stretching and to facilitate reaching
the apex of the rectal stump. Sizers are not usually required for these cases, although
they are sometimes used to gently stretch the rectum. In rare cases, a hand-sewn
colorectal anastomosis may be performed, and this can be performed through a
short Pfannenstiel incision.
Fistula Repair
The enteric and colon sides of stulas are generally both resected as segmental
resections (Fig.5.3). In the setting of Crohn’s disease, it is necessary to rst evaluate
both for active inammation. If the tissues are actively inamed, then a stula repair
is not advisable, and formal resection should be carried out (Figs.5.4 and 5.5a, b).
If there is no surrounding inammation, a tiny stula in small bowel may be managed with a wedge resection and hand-sewn closure of the enterotomy. While some
surgeons advocate selective use of stapling across stulas when only one of the
bowel segments is involved with Crohn’s disease, we do not routinely staple across
stula tracts, as we feel this is by denition abnormal tissue and at higher risk for
recurrence. We tend to reserve this for patients with multiple prior Crohn’s resections and less residual small bowel (Fig.5.6a–c). For more discussions on laparoscopic management of complex Crohn’s ileocolic disease, please refer to the chapter
on advanced laparoscopic right colectomy techniques (Chap. 16).
Small colovesical stulas are tested by distending the bladder with very dilute
methylene blue. If there is no leak, they are not sutured. Larger stulas are repaired
with laparoscopic suturing. An omental pedicle graft should be placed next to the
bladder, and a drain should be placed and monitored in case of a urine leak. A contrast study is done at 48hours for small stulas. Larger (sutured) stulas are imaged

5 Masters Program Colorectal Pathway: Laparoscopic Left Colon Resection…
69
at 2weeks by cystography before removing the Foley catheter. Vaginal stulas are
left open unless they are large in which case they are sutured with absorbable
sutures. An omental pedicle graft is placed over the defect when possible.
Other Steps
A segment of omentum is brought down as an omental pedicle graft between any
remaining wall of a stula or abscess cavity if reach permits. Drains are placed into
residual contained abscess cavities, although not if the abscess cavity has not been
mostly excised. Surgical wounds are closed in a standard fashion, and a wound
protector is used in all cases. Vacuum-assisted (VAC) dressings are not used. In rare
cases of extreme purulence or wound contamination, the wound is partially closed
and a betadine wick is inserted and removed on POD3 for delayed primary closure.
If there is a colocutaneous stula that requires excision of the abdominal wall and
skin (Fig.5.1a, b), these defects are typically managed with wet to dry dressing
changes, which can be switched to negative pressure dressing changes once healthy
granulation tissue is visible. The utilization of laparoscopy helps reduce the rates of
surgical site infection when compared to open operations. Standard enhanced recovery protocols and intraoperative surgical site infection measures are implemented.
Pitfalls andTroubleshooting
The level of difculty can range from straightforward to highly complex depending
on the degree of severity of the inammation. The learning curve in general for
laparoscopic left colectomy is upward of 50 cases and may not necessarily include
the challenges specic to safely managing penetrating CD [13]. Common challenges include the ability to separate the colon from adjacent structures, identifying
and protecting the left ureter, managing the difcult Crohn’s mesentery, and closure
of the stula on the organ remaining in situ (typically bladder or vagina). When
separating the colon from adjacent structures, if standard techniques are not successful, some surgeons favor conversion to hand-assist to optimize blunt dissection
while minimizing the size of the incision to maintain the benets of a laparoscopic
approach.
Identifying the ureter can be difcult in the setting of severe inammation. Keep
in mind that the ureter may be more medial than normal. Ureteral stents may be
placed preoperatively or intraoperatively if necessary [14]. We tend to favor selective intraoperative placement since a previous study we performed showed that this
made surgery faster and was just as manageable for urology [14]. Typically, ureteral
stents may help identify but not prevent ureteral injuries, and their presence should
not supplant safe dissection and knowledge of the anatomy.
The mesentery in CD can be challenging as it is frequently thickened, friable,
woody, and tends to bleed easily. Even when taking segments of mesentery with
small vascular branches, blood loss can be quite signicant. When using an energy

70
A. R. Bhama and C. P. Delaney
device, it may be necessary to take the mesentery in layers and cauterize/seal the
vessel in multiple locations prior to ligation. Endoloop® (Ethicon, Somerville, NJ,
USA) and endoscopic clip appliers may be helpful when taking named vessels and
should be available.
The predominant overarching theme in completing these cases laparoscopically
should be safety. Safe and quality surgical technique should not be compromised for
the sole purpose of completing the case in a minimally invasive fashion. Specically,
in cases where there is difculty in managing a bleeding mesentery or a question of
integrity of bowel, bladder, or vaginal repair; conversion is indicated. Conversion is
also indicated for several technical reasons such as inability to establish or maintain
pneumoperitoneum, inability to maintain adequate visualization, or inability to
clear gross fecal contamination.
Outcomes
While no specic studies evaluate left-sided colectomy specically, several studies
have shown that segmental colectomy for CD can be performed safely [6, 7, 11, 15].
The review article by Lightner and colleagues examined the results of six studies
looking at colectomy in Crohn’s disease with a follow-up ranging from 5 to 14years
[11]. However, they conclude that 50–65% of patients will have recurrent disease
involving the colon requiring additional immunosuppression. Furthermore, up to
57% will require additional operation, and 5–35% will have a permanent stoma due
to medically refractory disease (Table5.1).
A meta-analysis by Tekkis and colleagues included six studies comparing segmental resection vs subtotal/total colectomy with ileorectal anastomosis. A total of
488 patients with CD were included (223 ileorectal anastomosis patients and 265
segmental colectomy patients). The time to recurrence was longer in patients who
had total colectomy with ileorectal anastomosis by 4.4 years (95% CI 3.1–5.8,
P<0.001), but there was no difference in the incidence of postoperative complications (OR=1.4, 95% CI 0.16–12.74) or the need for a permanent stoma between the
Table 5.1 Recurrence rates after segment resection for Crohn’s colitis
Year
Author
Longo [8] 1988 21 62 5
Prabhakar
Makowiec
[9]
Andersson
[5]
Martel
Fichera [10] 2005 55 61 5.1
Modied with permission of Oxford University Press from Lightner [11]
a
Prabhakar etal. [24]
b
Martel etal. [25]
published
a
1997 49 49 14
1998 141 63 10
2002 31 39 13
b
2002 4 65 8.7
Number of
patients
Percent
recurrence
Average length of follow-up
(years)

5 Masters Program Colorectal Pathway: Laparoscopic Left Colon Resection…
71
two groups (OR=2.75, 95% CI 0.78–9.71) demonstrating that both segmental colectomy and total abdominal colectomy with ileorectal anastomosis were safe and
effective treatment options for colonic CD, even though patients who underwent
segmental colectomy exhibited earlier recurrence than those in the ileorectal anastomosis group. Their recommendation was that for patients with medically refractory CD, a segmental resection may be preferred in the setting of segmental colitis
and absence of perianal disease since the disease recurs regardless of the operative
approach. Total proctocolectomy with an end ileostomy remains the preferred
approach in the setting of colonic dysplasia.
Regarding the use of minimally invasive surgery in CD, the benets of laparoscopy for ileocolonic resections have been well-established even in the setting of
abscess, stula, and recurrent disease [2, 16–18]. The feasibility of laparoscopy for
complex stulizing disease has been described with similar outcomes to that of
nonstulizing disease [19–21]. In the prospective study by Goyer and colleagues,
postoperative outcomes between patients with CD undergoing laparoscopic ileocolic resection for uncomplicated disease were compared with those undergoing laparoscopic ileocolic resection for complicated or recurrent disease [21]. A total of 124
consecutive patients were analyzed over a 9-year period. The indications for laparoscopic ileocolic resection within the cohort of complex CD included stula (43%),
abscess (30%), and recurrent disease after prior ileocolic resection (27%). Although
complex disease was signicantly associated with increased average operative time
(214±13 vs 191±53minutes, P<0.05), increased conversion rate to open procedure (37% vs 14%, P<0.01), and increased use of a temporary stoma (39% vs 9%,
P <0.001), the overall postoperative morbidity was similar between both groups
(17% vs 17%, P=not signicant(NS)), including major surgical postoperative complications (7% vs 6%, P=NS). The average hospital stay was also not statistically
different between both groups (8 vs 7days, P=NS) [21]. This prospective study of
consecutive patients suggests that laparoscopy in complex CD is safe and feasible.
With regards to minimally invasive approach to colectomy in patients with CD,
despite a paucity of contemporary studies on this topic, older studies have demonstrated laparoscopy to be safe and feasible when performed at centers of expertise.
A single institutional experience was described by Holubar and colleagues identifying a total of 92 patients with CD undergoing minimal invasive colectomy from
1997 to 2008 [22]. Procedures included 43 total colectomies, 17 subtotal colectomies, and 32 segmental colectomies. Overall, straight laparoscopy was used in 57%
of cases and 43% were hand-assisted with no signicant difference in operative
times between lap- and hand-assisted groups. The rate of conversion to open laparotomy was 16%, and only small bowel disease predicted conversion (OR 7 (1.6–
35)). Conversion was not associated with increased length of hospital stay or
postoperative complications. Overall postoperative length of stay was 5 (4–7) days
with a 34% rate of early postoperative complications. Only perianal disease predicted complications after multivariate analysis (OR 2.6 (1.0–6.6)).
A case-matched study by da Luz Moreira and colleagues analyzing Crohn’s
patients undergoing laparoscopic vs open colectomy showed that although median
operative times were signicantly longer in the laparoscopic cohort (240 vs 150min,

72
A. R. Bhama and C. P. Delaney
P<0.01), postoperative complications were similar and the laparoscopic group had
shorter median length of stay (5 vs 6days, P=0.07) and median time to rst bowel
movement (3 vs 4days, P=0.4) [23].
Conclusions
Laparoscopy is feasible and safe in patients with abscess or stula due to inammatory bowel disease. It is important to thoroughly evaluate the patient and optimize
preoperative parameters through management of medications, nutrition, and utilization of enhanced recovery pathways. It is important to recognize patient-specic
contraindications and surgeon-specic limitations in attempting to approach these
operations laparoscopically. Several unique considerations need to be observed in
order to perform a safe operation, and conversion should be considered whenever
safety or quality is in question.
References
1. Fleshman J, Peters W.The Management of Crohn’s colitis. In: Cameron J, Cameron A, editors.
Current surgical therapy. 12th ed. Philadelphia: Elsevier; 2017.
2. Duepree H, Senagore A, Delaney C, Brady K, Fazio V.Advantages of laparoscopic resection
for ileocecal Crohn’s disease. Dis Colon Rectum. 2002;45(5):605–10.
3. Delaney C, Lawrence J, Keller D, Champagne B, Senagore A.Operative techniques in laparo-
scopic colorectal surgery. Philadelphia: Lippincott, Wiliiams, & Wilkins; 2014.
4. Bosio R, Delaney C. Surgical treatment of diverticulitis and its complications. In: Fazio V,
Church J, Delaney C, Kiran P, editors. Current therapy in colon and rectal surgery. Philadelphia:
Elsevier; 2017.
5. Andersson P, Olaison G, Hallböök O, Sjödahl R.Segmental resection or subtotal colectomy in
Crohn’s colitis? Dis Colon Rectum. 2002;45(1):47–53.
6. Angriman I, Pirozzolo G, R B CF, Castoro C, Scarpa M.A systematic review of segmental
vs subtotal colectomy and subtotal colectomy vs total proctocolectomy for colonic Crohn’s
disease. Color Dis. 2017;19(8):279–87.
7. Sanfey H, Bayless T, Cameron J.Crohn’s disease of the colon. Is there a role for limited resec-
tion? Am J Surg. 1984;147(1):38–42.
8. Longo W, Ballantyne G, Cahow C.Treatment of Crohn’s colitis. Segmental or total colec-
tomy? Arch Surg. 1988;123(5):588–90.
9. Makowiec F, Paczulla D, Schmidtke C, Starlinger M.Long-term follow-up after resectional sur-
gery in patients with Crohn’s disease involving the colon. Z Gastroenterol. 1998;36(8):619–24.
10. Fichera A, McCormack R, Rubin M, Hurst R, Michelassi F.Long-term outcome of surgically
treated Crohn’s colitis: a prospective study. Dis Colon Rectum. 2005;48(5):963–9.
11. Lightner A.Segmental resection versus total proctocolectomy for Crohn’s colitis: what is the
best operation in the setting of medically refractory disease or dysplasia? Inamm Bowel Dis.
2018;24(3):532–8.
12. Delaney C, Bosio R.Chapter 7: Optimizing outcomes with enhanced recovery. In: Steele S,
Hull T, Read T, Saclarides T, Senagore A, Whitlow C, etal., editors. The ASCRS textbook of
colon and rectal surgery. 3rd ed. NewYork: Springer International Publishing; 2017.
13. Toledano Trincado M, Sánchez Gonzalez J, Blanco Antona F, Martín Esteban M, Colao García
L, Cuevas Gonzalez J, etal. How to reduce the laparoscopic colorectal learning curve. JSLS.
2014;18(3):e2014.00321.

5 Masters Program Colorectal Pathway: Laparoscopic Left Colon Resection…
14. Pokala N, Delaney C.A randomized controlled trial comparing simultaneous intra-operative
vs sequential prophylactic ureteric catheter insertion in re-operative and complicated colorectal surgery. Int J Color Dis. 2007;22(6):683–7.
15. Tekkis P, Purkayastha S, Lanitis S, Athanasiou T, Heriot A, Orchard T, etal. A comparison of
segmental vs subtotal/total colectomy for colonic Crohn’s disease: a meta-analysis. Color Dis.
2006;8(2):82–90.
16. Favuzza J, Delaney C.Laparoscopic ileocecectomy small bowel resection and stritureplasty
for Crohn’s disease. In: Nguyen N, Scott-Conner C, editors. The SAGES manual. 2nd ed.
NewYork: Springer International Publishing; 2012.
17. Heimann T, Swaminathan S, Greenstein A, Greenstein A, Khaitov S, Steinhagen R, etal. Can
laparoscopic surgery prevent incisional hernia in patients with Crohn’s disease: a comparison study of 750 patients undergoing open and laparoscopic bowel resection. Surg Endosc.
2017;31(12):5201–8.
18. Nguyen S, Teitelbaum E, Sabnis A, Bonaccorso A, Tabrizian P, Salky B.Laparoscopic resec-
tion for Crohn’s disease: an experience with 335 cases. Surg Endosc. 2009;23(10):2380–4.
19. Pokala N, Delaney C, Brady K, Senagore A.Elective laparoscopic surgery for benign internal
enteric stulas: a review of 43 cases. Surg Endosc. 2005;19(2):222–5.
20. Wen Y, Althans A, Brady J, Dosokey E, Choi D, Nishtala M, etal. Evaluating surgical manage-
ment and outcomes of colovaginal stulas. Am J Surg. 2017;213(3):553–7.
21. Goyer P, Alves A, Bretagnol F, Bouhnik Y, Valleur P, Panis Y.Impact of complex Crohn’s
disease on the outcome of laparoscopic ileocecal resection: a comparative clinical study in 124
patients. Dis Colon Rectum. 2009;52(2):205–10.
22. Holubar S, Dozois E, Privitera A, Pemberton J, Cima R, Larson D. Minimally invasive
colectomy for Crohn’s colitis: a single institution experience. Inamm Bowel Disease.
2010;16(11):1940–6.
23. da Luz Moreira A, Stocchi L, Remzi F, Geisler D, Hammel J, Fazio V.Laparoscopic surgery for
patients with Crohn’s colitis: a case-matched study. J Gastrointest Surg. 2007;11(11):1529–33.
24. Prabhakar LP, Laramee C, Nelson H, Dozois RR.Avoiding a stoma– role for segmental or
abdominal colectomy in Crohn’s colitis. Dis Colon Rectum. 1997;40(1):71–8.
25. Martel P, Betton PO, Gallot D, Malafosse M.Crohn’s colitis: experience with segmental resec-
tions; results in a series of 84 patients. J Am Coll Surg. 2002;194(4):448–53.
73

Part II
Preoperative Considerations
Соседние файлы в папке Библиотека им академика М.И. Перельмана
