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prior mesh. If there is no clear plane between the mesh and the intestine, a portion of the mesh should be excised and left adherent on the bowel rather than risking an enterotomy.
A. M. Coker and G. L. Adrales

Hernia Defect Assessment

Accurate measurement of the fascial defect is an essential step in successful LVHR as this will allow an estimation of the appropriate-sized prosthetic to be placed. Extracorporeally, the defect can be dened by palpation, but this is often inaccurate. Laparoscopy, in contrast, allows a direct visualization of the defect. A measurement is then obtained by intracorporeal placement of a ruler or an umbilical tape with 2cm markings [21]. Spinal needles, utilized to mark the edges of the defect, can assist in accurate measurement [5]. Alternatively, a suture is inserted and held across the distance between the two spinal needles and then is measured extracorporeally.
A signicant advantage of LVHR over open repair is the ability to evaluate for additional defects that could not be palpated. Several studies have demonstrated high rates of these occult defects that are appreciated only at the time of LVHR [22,
23]. In this case, measurement should encompass all visible defects so that adequate
mesh coverage can be achieved. In the case of incisional hernias, consideration should also be given to measuring and covering the entirety of the scar to prevent new hernias from forming [24].

Defect Closure

In its early conception, LVHR did not involve closure of the defect but was essen­tially a bridging repair. There are now several methods of defect closure described in the literature. A chapter in this book is devoted to the pros and cons of traditional IPOM versus that with defect closure, so it is mentioned only briey here. Probably the most commonly applied method is the “shoelacing technique” described by Orenstein etal. This is an extracorporeal closure utilizing a suture passer to create a series of gure-of-eight stitches [25]. Intracorporeal closure and hybrid techniques for defect closure have been described as well [23, 26, 27]. Potential benets of defect closure include reconstruction of a functional abdominal wall, closure of dead space that can lead to seroma formation, reduction in recurrence rate, and pre­vention of mesh eventration and bulging [27, 28].
Mesh Selection andSizing
Many hernia surgeons are in favor of utilizing mesh for their open repairs in an effort to reduce recurrence rates. There are surgeons, however, who favor a primary repair and avoid the use of prosthetics when possible. There is no room for debate when it comes to laparoscopic hernia repair, as the technique can only be
2 Laparoscopic Ventral Hernia Repair
17
accomplished with the use of mesh. The topic of which mesh could ll the pages of an entire book. Indeed, there are four chapters in this book devoted to the topic of prosthetics and mesh selection, so we will refer the reader to those for details regard­ing the subject. In brief, the principal selection criteria for a laparoscopic repair are based on whether the mesh will be directly exposed to the bowel. When performing an IPOM repair, the mesh is in direct contact with the bowel, and, thus, a mesh with an adhesion barrier is critical in the pursuit of avoiding complications of small bowel obstructions and stulae [29]. Most manufacturers of polypropylene or poly­ester meshes offer a product with an adhesion barrier on the visceral side. Typically, this is a hydrophilic component that resorbs over time. Alternatively, expanded polytetrauoroethylene (ePTFE) is less adhesiogenic, and thus prosthetics com­posed of this do not have an additional adhesion barrier [30]. In contrast, the parietal side of the mesh should facilitate tissue ingrowth to provide secure xation. In an effort to achieve this ideal mesh, there are products composed of two different com­ponents available as well. If a transabdominal pre-peritoneal approach is utilized, a non-coated mesh is preferred. The peritoneum protects the viscera from the mesh, so no other barrier is needed, and some would argue anything else would interfere with ingrowth and potentially increase risk for seroma formation.
Whatever mesh is chosen, the size must provide adequate overlap of the defect. Obviously, this could be approached by choosing very large mesh for all defects. This, however, would be expensive, and the increased surface area requires more xation and thus potential for complications such as chronic pain. The larger pros­thetic would also be problematic if complications were to arise such as infection requiring explanation. The goal then is to utilize a mesh that provides enough over­lap to account for potential shifting of the mesh as well as shrinkage. The increased surface area with overlap allows for more ingrowth and, thus, biologic xation. Additional support occurs from the effect of intra-abdominal pressure on the increased surface area of a larger mesh [28].
There is little high-level evidence to dictate what the minimal amount of overlap should be for a LVHR. Studies are limited by variations in technique and small sample sizes [28]. One of the largest series of LVHR utilized a 3cm overlap early in the series and then shifted to a 4cm overlap [31]. Many surgeons now prefer a 5cm overlap of the defect, and recurrence rates have been acceptable with this tech­nique [5]. Thus, after measuring the defect size, 6–10cm is added to the transverse and vertical dimensions to determine the minimum mesh size that should be utilized in the repair. There is general consensus that the larger the defect size, the larger the overlap should be [28].
As it becomes more common practice to close the hernia defect, there is some debate as to whether a smaller-sized mesh will sufce. Most commonly, a mesh size is selected based on the initial defect size as measured prior to closure. In doing so, if the fascial closure breaks down, one can be assured effective overlap remains.
Prior to inserting the mesh, the surgeon may wish to place marks in order to ori­ent the mesh with more ease. Some manufactures have marking for this purpose. Most importantly, if adhesion barrier mesh is utilized, one must be able to identify which is the coated visceral side and which is the peritoneal side. If transfascial
18
A. M. Coker and G. L. Adrales
sutures are to be used, part or all of these can be secured to the mesh prior to inser­tion as well.
Introducing the mesh to the abdomen can be accomplished by placing the rolled mesh directly through a trocar. This has the benet of avoiding any skin contact with the prosthetic. This does, however, require a larger trocar as it would be a struggle to insert coated mesh through a 5mm port. If the surgeon wishes to use only 5mm trocars or needs to insert a very large mesh, this is accomplished by passing a grasper out directly through a trocar from the contralateral side. The trocar is then removed and the mesh pulled into the abdomen through the port site, prior to replac­ing the trocar.

Mesh Fixation

Positioning the mesh, especially larger sizes of mesh, is aided by the use of either a commercially available positioning device or simply by use of sutures placed prior to insertion. A suture passer is utilized to externalize the sutures and, thus, suspend the mesh. These can be subsequently removed, once methods of xation are in place, or utilized as transfascial xation points.
After the mesh is positioned, with appropriate overlap conrmed, the options for securing the mesh to the abdominal wall are tacks, transfascial sutures, glue, or some combination of these. The traditional technique involves placement of at least four transfascial sutures at equidistant points. Additional transfascial sutures may be placed, as deemed necessary, to secure larger prosthetics. The perimeter is then tacked to the posterior fascia at approximately 1cm intervals [31]. The edge of the mesh should be secured close to the perimeter to avoid exposing bowel to the non­coated side of the mesh, if applicable. With any method of xation, care should be taken to avoid injury to the epigastric vessels.
While suture is categorized as only absorbable or nonabsorbable, tacking options vary in design and material. Typically, tacks are helical or pronged, and available prod­ucts vary in depth of penetration as well. There is evidence that, at least in short term follow-up, acute and chronic postoperative pain is not signicantly different between the absorbable and nonabsorbable categories of tacks [32]. The tacking device can be utilized to secure the mesh around the perimeter between transfascial sutures, or can be utilized without transfascial sutures, often in a “double-crown” fashion. A random­ized study evaluating acute postoperative pain found similar postoperative pain and quality-of-life ndings between the double-crown technique with no sutures and trans­fascial sutures (either absorbable or nonabsorbable) with tacks. The same study noted decreased operative time in the group without transfascial sutures [33].
This is yet another controversial topic, and there is a paucity of high-level evi­dence regarding the best method to prevent recurrence and optimize the patient experience. Studies have demonstrated that suture xation achieves the highest ten­sile strength in comparison to alternative devises and decreases mesh shrinkage [34,
35]. Still, this has failed to consistently demonstrate a reduction in recurrence rates.
2 Laparoscopic Ventral Hernia Repair
A meta-analysis comparing only suture xation, only tack xation, and a combina­tion of sutures and tacks failed to detect a signicant difference regarding the recur­rence rates at follow-up periods of at least 2years [28].
19
Postoperative Care andOutcomes
Laparoscopic ventral hernia repair is associated with shorter hospitalization, decreased wound complications, and reduced surgical site infection rate compared to open repair [3638].
In a systematic review and meta-analysis, the laparoscopic approach consistently reduced the risk of wound infection. (RR=0.26; 95% CI 0.15–0.46; I(2)= 0%) [39]. While the minimally invasive approach may be associated with a longer operative time and higher operative cost, this lower risk of surgical site infection can reduce substantially the overall cost and burden on the patient associated with readmission and wound care.

Bowel Injury

The serious morbidity and mortality rate associated with LVHR is low. However, inadvertent enterotomy signicantly increases the mortality risk. A literature review assessed that bowel injury occurs in almost 2% of patients, and large bowel injury comprises 8.3% of these cases. These injuries are identied and repaired approxi­mately 80% of the time during the hernia repair. Enterotomy increased the mortality risk from 0.05 to 2.8% [20]. Despite the technical advances of magnied visualiza­tion, the rate of bowel injury remains higher for LVHR compared to open repair in at least two systematic reviews [38, 39].
Meticulous adhesiolysis to avoid thermal bowel injury as well as traction injury and close inspection for injury during laparoscopic repair are warranted. Identied injuries must be repaired immediately either laparoscopically or via laparotomy depending on the comfort of the surgeon. Gross contamination precludes permanent mesh placement. Postoperatively, patients may have signicant incisional pain but should be hemodynamically stable. Fever, tachycardia, uid sequestration, and ery­thema are all worrisome signs of a missed enterotomy.

Seroma

Seroma is common after laparoscopic ventral hernia but few require intervention [4,
31]. This can occur with transfascial sutures and with the double-crown technique
of mesh xation. The seroma is often within the old hernia sac but may occur as a retroprosthetic seroma in almost half of patients in the early recovery period [40]. Primary fascial closure reduces the seroma rate [41].
20
A. M. Coker and G. L. Adrales

Pain Management

Enhanced recovery pathways with multimodal pain management reduce the nar­cotic usage and subsequent adverse effects such as ileus. Preoperative anti­inammatory medication and acetaminophen as well as local anesthetic injection during the procedure may reduce postoperative pain. Pain has been associated with both transfascial sutures and tack xation, without a demonstrable difference between absorbable and permanent tacks [42].

Hernia Recurrence

In a single series, the hernia recurrence rate after laparoscopic ventral hernia repair varies from 3 to 20%, though follow-up is limited. In a recent Cochrane review, the recurrence rate was comparable between laparoscopic and open repair, but the follow- up was shorter than 2years in half of the included trials [39]. Mesh overlap of the defect is critical in reducing the rate of hernia recur­rence. The risk of hernia recurrence is inversely correlated with increasing mesh overlap in laparoscopic repair. In laparoscopic procedures, the pooled estimation of risk for recurrence of hernia decreased with increasing area of mesh overlap (<3cm, incidence rate 0.086; 3–5cm, incidence rate 0.046; >5cm, incidence rate 0.014) [43].

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9. Ousley J, Baucom RB, Stewart MK, Phillips SE, Holzman MD, Ehrenfeld JM, Sharp KW,
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2 Laparoscopic Ventral Hernia Repair
10. Mercoli H, Tzedakis S, Antonio D’U, Nedelcu M, Memeo R, Meyer N, Vix M, Perreta S,
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MK.Adverse events after ventral hernia repair: the vicious cycle of complications. J Am Coll Surg. 2015;221(2):478–85.
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vention. A systematic review of the literature. World J Surg. 2016;40(10):2331–41.
14. Granata M, Tsimpanakos I, Moeity F, Magos A.Are we underutilizing Palmer’s point entry in
gynecologic laparoscopy? Fertil Steril. 2010;94(7):2716–9.
15. Comajuncosas J, Hermoso J, Gris P, etal. Risk factors for umbilical trocar site incisional hernia
in laparoscopic cholecystectomy: a prospective 3-year follow-up study. Am J Surg. 2014;207:1– 6; Mayol JM, Garcia-Aguilar J, Ortiz-Oshiro E, etal. World J Surg. 1997;21:529–33.
16. Parker MC, Wilson MS, van Goor H, Moran BJ, Jeekel J, Duron JJ, Menzies D, Wexner SD,
Ellis H.Adhesions and colorectal surgery—call for action. Color Dis. 2007;9(Suppl 2):66–72.
17. Liakakos T, Thomakos N, Fine PM, Dervenis C, Young RL.Peritoneal adhesions: etiology,
pathophysiology, and clinical signicance. Recent advances in prevention and management. Dig Surg. 2001;18:260–73.
18. Kössi J, Salminen P, Rantala A, Laato M.Population-based study of the surgical workload
and economic impact of bowel obstruction caused by postoperative adhesions. Br J Surg. 2003;90:1441–4.
19. Menzies D, Ellis H.Intestinal obstruction from adhesions—how big is the problem? Ann R
Coll Surg Engl. 1990;72:60–3.
20. LeBlanc KA, Elieson MJ, Corder JM III.Enterotomy and mortality rates of laparoscopic inci-
sional and ventral hernia repair: a review of the literature. JSLS. 2007;11(4):408–14.
21. Birch DW. Characterizing laparoscopic incisional hernia repair. Can J Surg. 2007;50(3):
195–201.
22. Saber AA.Occult ventral hernia defects: a common nding during laparoscopic ventral hernia
repair. Am J Surg. 2008;195(4):471–3.
23. Sharma D, Jindal V, Pathania OP, Thomas S.Novel technique for closure of defect in laparo-
scopic ventral hernia repair. J Minim Access Surg. 2010;6(3):86–8.
24. Wassenaar E, Schoenmaeckers E, Raymakers J, Rakic S. Recurrences after laparoscopic
repair of ventral and incisional hernia: lessons learned from 505 repairs. Surg Endosc. 2009;23(4):825–32.
25. Orenstein S, Dumeer J, Monteagudo J, Poi M, Novitsky Y.Outcomes of laparoscopic ven-
tral hernia repair with routine defect closure using “shoelacing” technique. Surg Endosc. 2011;25(5):1452–7.
26. Chelala E, Thoma M, Tatete B, Lemye A, Dessily M, Alle J.The suturing concept for laparo-
scopic mesh xation in ventral and incisional hernia repair: mid-term analysis of 400 cases. Surg Endosc. 2007;21(3):391–5.
27. Suwa K, Okamoto T, Yanaga K.Closure versus non-closure of fascial defects in laparoscopic
ventral and incisional hernia repairs: a review of the literature. Surg Today. 2016;46(7):764–73.
28. Bittner R, Bingener-Casey J, Dietz U, Fabian M, Ferzli G, Fortelny R, etal. Guidelines for lap-
aroscopic treatment of ventral and incisional abdominal wall hernias (International Endohernia Society (IEHS))—part 1. Surg Endosc. 2014;28(1):2–29.
29. Amid PK, Shulman AG, Lichtenstein IL, Sostrin S, Young J, Hakakha M.Experimental evalu-
ation of a new composite mesh with the selective property of incorporation to the abdominal wall without adhering to the intestines. J Biomed Mater Res. 1994;28(3):373–5.
30. Bellón JM, Contreras LA, Buján J, Pascual G, Carrera-San Martín A. Effect of relaparot-
omy through previously integrated polypropylene and polytetrauoroethylene experimental implants in the abdominal wall. J Am Coll Surg. 1999;188(5):466–72.
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31. Heniford BT, Park A, Ramshaw BJ, Voeller G.Laparoscopic repair of ventral hernias: nine
years' experience with 850 consecutive hernias. Ann Surg. 2003;238(3):391–4.
32. Bansal V, Asuri K, Panaiyadiyan S, Kumar S, Subramaniam R, Ramachandran R, et al.
Comparison of absorbable versus nonabsorbable tackers in terms of long-term outcomes, chronic pain, and quality of life after laparoscopic incisional hernia repair: a randomized study. Surg Laparosc Endosc Percutan Tech. 2016;26(6):476–83.
33. Wassenaar E, Schoenmaeckers E, Raymakers J, van der Palen J, Rakic S. Mesh-xation
method and pain and quality of life after laparoscopic ventral or incisional hernia repair: a randomized trial of three xation techniques. Surg Endosc. 2010;24(6):1296–302.
34. Riet M, Steenwijk PJ, Kleinrensink GJ, Steyerberg EW, Bonjer HJ.Tensile strength of mesh
xation methods in laparoscopic incisional hernia repair. Surg Endosc. 2002;16(12):1713–6.
35. Beldi G, Wagner M, Bruegger L, Kurmann A, Candinas D.Mesh shrinkage and pain in lapa-
roscopic ventral hernia repair: a randomized clinical trial comparing suture versus tack mesh xation. Surg Endosc. 2011;25(3):749–55.
36. Muller-Riemenschneider F, Roll S, Friedrich M, Zieren J, Reinhold T, von der Schulenburg
JM, Greiner W, Willich SN.Medical effectiveness and safety of conventional compared to laparoscopic incisional hernia repair: a systematic review. Surg Endosc. 2007;21:2127–36.
37. Arita NA, Nguyen MT, Nguyen DH, Berger RL, Lew DF, Suliburk JT, Askenasy EP, Kao LS,
Liang MK.Laparoscopic repair reduces incidence of surgical site infections for all ventral hernias. Surg Endosc. 2015;29(7):1769–80.
38. Zhang Y, Zhou H, Chai Y, Cao C, Jin K, Hu Z.Laparoscopic versus open incisional and ventral
hernia repair: a systematic review and meta-analysis. World J Surg. 2014;38(9):2233–40.
39. Sauerland S, Walgenbach M, Habermalz B, Seiler CM, Miserez M. Laparoscopic versus
open surgical techniques for ventral or incisional hernia repair. Cochrane Database Syst Rev. 2011;3:CD007781.
40. Morales-Conde S, Suarez-Artacho G, Socas-Macias M, Barranco-Moreno A.Retroprosthetic
seroma after laparoscopic ventral hernia repair: incidence, risk factors and clinical signi­cance. Hernia. 2015;19(6):943–7.
41. Tandon A, Pathak S, Lyons NJ, Nunes QM, Daniels IR, Smart NJ.Meta-analysis of clo-
sure of the fascial defect during laparoscopic incisional and ventral hernia repair. Br J Surg. 2016;103(12):1598–607.
42. Reynvoet E, Berrevoet F.Pros and cons of tacking in laparoscopic hernia repair. Surg Technol
Int. 2014;25:136–40.
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scopic ventral and incisional hernia repair. Hernia. 2016;20(1):85–99.
A. M. Coker and G. L. Adrales

Masters Program Hernia Pathway: Laparoscopic Inguinal Hernia

JacquelineBlank andMatthewI.Goldblatt

Introduction

Laparoscopic inguinal hernia repair is among the most common procedures per­formed today by general surgeons. There is increasing data that laparoscopic sur­gery has the advantage of decreased postoperative pain and quicker return to normal daily activities, and it may even afford better visualization of a challenging ana­tomic region. However, there is considerable variety among general surgeons regarding the operative technique for laparoscopic inguinal hernia repair.
Laparoscopic inguinal hernia repairs may be performed via a totally extraperito­neal (TEP) approach or a transabdominal preperitoneal (TAPP) approach. The choice between a laparoscopic TEP and TAPP inguinal hernia repair is based on patient history and surgeon preference. Previous disruption of the preperitoneal space is a relative contraindication for a TEP repair, as is done with prostate surgery. A TAPP repair may be advantageous when performing with concurrent laparo­scopic abdominal operations like a laparoscopic ventral hernia [1]. For repair of bilateral inguinal hernias, both TEP and TAPP are preferred over open repair. Laparoscopic repair is also ideal for recurrent inguinal hernia repair after open sur­gery, because the preperitoneal space has not yet been disrupted [2]. Lastly, laparo­scopic femoral hernia repairs have been shown to have lower recurrence rates than open repairs of femoral hernias in women [3].
In the case where both TEP and TAPP are possible, the surgeon must consider the risks and benets of each approach, as there is mixed data regarding the morbid­ity and mortality of each. A meta-analysis by Antoniou and colleagues examined
3
J. Blank · M. I. Goldblatt (*) Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA e-mail: mgoldbla@mcw.edu; jblank@mcw.edu
© Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) 2019 S. S. Davis Jr. et al. (eds.), The SAGES Manual of Hernia Surgery,
https://doi.org/10.1007/978-3-319-78411-3_3
23
24
over 500 patients that underwent TEP and TAPP laparoscopic repairs and found no difference in hernia recurrence or long-term pain or sensory decits between the two approaches [4]. There was increased operative morbidity of TAPP when com­pared to TEP (OR=2.15; 95% CI, 1.29 to 3.61; P=0.004); however, this particular metric was heavily inuenced by variable denitions of morbidity among studies [4]. Other studies also differ on results of early and late postoperative pain control for each approach [5, 6]. The decision between the TEP and TAPP approaches will be discussed in more detail in future chapters.
In this chapter, we will discuss preoperative and intraoperative techniques for laparoscopic inguinal hernia repairs (both TEP and TAPP), including relevant anat­omy, operative dissection, mesh placement, and common complications.
J. Blank and M. I. Goldblatt
Patient Preparation andPositioning
After appropriate medical evaluation and informed consent, the patient is placed in a supine position. Preoperative antibiotics are given within 1h of the rst skin inci­sion. Venous thromboembolism (VTE) prophylaxis may be used for patients at moderate or higher risk of postoperative VTE according to the guidelines set forth by the American College of Chest Physicians (ACCP), which are endorsed by the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) [7]. Those at very low and low risk for postoperative VTE require only pneumatic com­pression devices and early postoperative mobilization for VTE prophylaxis [7].
Once general endotracheal anesthesia is initiated, the arm contralateral to the hernia is tucked. This allows the surgeon to stand at the patient’s shoulder. If the patient has bilateral hernias, then both arms are tucked. Many surgeons place a uri­nary catheter; however, others may forego this step (discussed in Sect. 3.7). Hair in the operative eld is removed using skin clippers. The abdomen is prepped from the costal margin to a few centimeters below the pubic symphysis and laterally to the posterior axillary lines. Drapes are then placed just above the umbilicus superiorly, the bilateral anterior superior iliac spines (ASIS) laterally, and the pubic symphysis inferiorly. The surgeon stands on the side contralateral to the hernia. For bilateral hernia, it is the surgeon’s preference as to which side to start. A single monitor is positioned at the feet for the surgeon and assistant (Fig.3.1) [810].

Laparoscopic Anatomy

The anatomy of the inguinal region can be challenging at rst. Laparoscopic inguinal hernia repair requires thorough knowledge of the anatomy of the preperitoneal space. The distal aspect of the preperitoneal space is called the space of Retzius, which is located between the pubic tubercle and the urinary bladder. The lateral extension of the space of Retzius is the space of Bogros [11]. The preperitoneal space is bounded anteriorly by the abdominal wall, which forms the “ceiling” of the laparoscopic
SS
MM
ab
3 Masters Program Hernia Pathway: Laparoscopic Inguinal Hernia
25
x
A
x
A
Fig. 3.1 Operating room setup and port placement for TEP repair (a) and TAPP repair (b) The surgeon stands contralateral to the hernia, and the arm contralateral to the hernia is tucked. The ipsilateral arm is left abducted for the anesthesiologist. X hernia, S surgeon, A assistant, M monitor. Open circle=10- or 12-mm port. Closed circles=5-mm ports
Fig. 3.2 Laparoscopic left inguinal hernia repair, with Cooper’s ligament (yellow line), inferior epigastric vessels (red line), spermatic cord (green line), and the iliopubic tract (blue line). A direct hernia will be medial to the epigastric vessels, in the region of the white circle. An indirect hernia will be lateral to the epigastric vessels, in the region of the white polygon. Med medial, Sup super­cial, Lat lateral
operating space. The inferior epigastric vessels should abut this wall when dissected properly (red line, Fig.3.2). The posterior portion of the preperitoneal space is cre­ated by the peritoneum overlying the abdominal contents, which forms the “oor.” The pubic tubercle is the medial landmark of the laparoscopic operating space, with the ASIS laterally. The inguinal ligament, or Poupart’s ligament, runs from the ASIS to the pubic tubercle. The shelving edge of the inguinal ligament connects the