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COMPLICATIONS

SurgicalSiteInfections/AnastomoticLeak
Despiteeffortstoreducetheirincidence,SSIsremaincommonfollowing colonandrectalresection,occurringinupto20%ofcases.Overall,the incidenceSSIsdoesappeartobelowerfollowinglaparoscopiccolorectal resection.Areviewofover16,000laparoscopicandopencolonresections includedintheAmericanCollegeofSurgeonsNationalSurgicalQuality ImprovementProgram(ACS-NSQIP)databaserevealeda15.7% incidenceofSSIintheopengroupcomparedto9.4%inthelaparoscopic group(P<0.00001).AtDUMC,theauthorsinstituteapreventativeSSI bundleforallopenandlaparoscopiccolonandrectalresections,which includesapreoperativechlorhexidineshower,mechanicalbowel preparationwithoralantibiotics,IVertapenem1hourbeforetheincision ismade,chlorhexidineskinpreparation,useofawoundprotector,gown andglovechangesbeforefascialclosure,andadedicatedclosure instrumenttray.UseofthispreventativeSSIbundlehasdecreasedthe incidenceofsuperficialSSIinourinstitutionfrom19.3%before implementationto5.7%followingimplementation(Table14-2).
TABLE14-2 ManagementofComplicationsFollowing
LaparoscopicLowAnteriorResection
Complication Management
Lowanterior resection syndrome (LARS)
Preoperative
Postoperative
ConsiderationofcolonicJ-pouch,transverse coloplastypouch,end-to-sidecolorectal anastomosis Bulkinglaxatives Pelvicfloorstrengtheningexercises Antimotilityagents Sacralnervestimulation(SNS) Biofeedback Retrograderectalirrigation Conversiontoastomaforsevere,refractory cases
Anastomotic leak
Preoperative
 
Postoperative
Considerdivertingloopileostomy(DLI) followingpreoperativechemoradiation and/orlowcoloanalanastomosis(<5cm fromanalverge)tolimitmorbiditysecondary toanastomoticleak
Basedonseverityofclinicalpresentation: Nontoxic,hemodynamicallystable,no peritonitis: IVantibiotics±percutaneousdrainageof intra-abdominalcollection Diffuseperitonitis,hemodynamicinstability: Laparoscopy/laparotomywithdiversionof anastomosiswithDLI,drainage
Smallbowel obstruction
Adhesive
 
Secondaryto suspectedvolvulus ofDLI
NPO,nasogastrictubedecompression; Operativemanagementforfailuretoresolve obstructionordevelopmentofperitoneal signs Promptlaparoscopy/laparotomy
Ureteralinjury
Preoperative Postoperative
Consideruseoflightedureteralstents Intraoperativeurologicalconsultation Laparoscopicrepairvs.conversiontoopen procedurebasedonavailableexpertise Ureteroneocystostomyvs.spatulationand primaryrepairoverastentversus ureteroureterostomybasedonlevelofinjury
Anastomoticleakisoneofthemostdevastatingcomplicationsof restorativerectalresectionandisassociatedwithconsiderablemorbidity andmortalityaswellasincreasedLOSandhealthcarecosts.The laparoscopicapproachtoTMEandrestorativerectalresectiondoesnot appeartoincreasetheincidenceofpostoperativeanastomoticleak.A recentmeta-analysisincludingsixrandomizedcontrolledtrialsdidnot findanysignificantdifferenceintheincidenceofpostoperative anastomoticleakbetweenopenandlaparoscopicLAR.Theauthors utilizemechanicalbowelpreparationwithPOantibioticsonallLARs basedonastudyfromtheauthors’institutionofNSQIPdatathatfound theincidenceofanastomoticleaktobesignificantlylowerinpatients withapreoperativebowelprepcomparedtothosewithnobowelprep (2.8%vs.5.7%).TheauthorsalsofrequentlyutilizeDLIforpatients undergoingcoloanalanastomosis,particularlyafterpreoperative chemoradiation.AlthoughtheissueofwhetherDLIreducestheincidence ofanastomoticleaksremainscontroversial,itseemscleartheDLIlessens theclinicalseverityofanastomoticleakwhenitoccurs.Theevaluation andmanagementofanastomoticleakagedoesnotdifferbetween laparoscopicandopenapproachesandhasbeenwelldescribed elsewhere.OptionsmayincludeIVantibioticsalone,CT-guided percutaneousdrainageofpelvicfluidcollections,andlaparoscopicDLIif
fecaldiversionisrequired.
SmallBowelObstruction
Smallbowelobstruction(SBO)isafrequentcomplicationfollowing majorabdominalsurgeryincludingcolonandrectalresection.The incidenceisprobablyhigherinpatientswhohaveaDLIsecondaryto obstructionattributabletotheostomy.Arecentstudyincludingover 69,000patientsfromastateregistrydemonstratedthattheincidenceof SBOwassignificantlylowerinpatientsfollowinglaparoscopiccolorectal resectioncomparedtothatinpatientswhounderwentopenresection. ThemanagementofSBOfollowinglaparoscopicLARisthesameasthat forpostoperativeSBOingeneral,mostofwhichcanbemanagedwith nasogastrictubedecompressionandexpectantmanagement.Inthecase ofSBOfelttobeduetothesmallbowelwrappingaroundaloop ileostomy,promptoperativemanagementisindicated.
p.108
p.109
ComplicationsRelatedtoDivertingLoopIleostomy
DLIisoftenperformedduringlaparoscopicLARasatemporaryfecal diversionforadistalcolorectal/coloanalanastomosis,particularlyafter preoperativechemoradiationtherapy.Thereisconflictingevidence regardingwhetheraDLIreducestheincidenceofanastomoticleak; however,aDLIlikelydecreasesthemorbidityandmortalityof anastomoticleakwhenitoccurs.Thisbenefitmustbecarefullyweighed againstthemorbidityandmortalityofanileostomy,includingthe potentialfordehydrationandacutekidneyinjury,difficultieswith pouching,leakageresultinginsignificantskindamage,prolapse, parastomalhernia,andSBO.Inaddition,thepotentialmorbidityof ileostomyreversalmustalsobeconsidered.Despitetheabilitytoclose mostileostomieswithoutalaparotomy,theprocedureisnottrivialandis associatedwithareportedmorbidityof17%,a0.4–0.6%mortality,a4% incidenceofconversiontolaparotomy,a7–15%incidenceofSBO,anda 2%incidenceofanastomoticleak.
UreteralInjury
Fortunately,injurytotheureterduringlaparoscopicrectalresectionis uncommon,occurringin1of240(0.4%)patientsundergoing laparoscopyintheACOSOGZ6501trial.Theuseoflightedureteralstents duringlaparoscopiccasesmayfacilitateintraoperativeidentificationof
theureters,helpavoidinjurytotheureters,andaidinprompt recognitionofureteralinjuries.Theabilitytocontinuallyidentifythe ureteralongitsentirecourseundoubtedlyallowsthedissectionto confidentlyandefficientlyproceed.Itisimportanttoensurethattheleft ureterisclearlyidentifiedbeforedivisionoftheprimaryvascularpedicle (IMAorsuperiorrectalartery)withanendo-GIAstaplerorenergy device.Anotherpotentialpointatwhichtheuretersareatriskforinjury isthepointwheretheycrossthepelvicbrim.Managementofureteral injuryhasbeenwelldescribedelsewhereandoptionsinclude ureteroneocystostomy,spatulationandprimaryrepairoverastent,and ureteroureterostomy.Thechoiceofrepairdependsonthelevelatwhich theinjuryoccurs.Theabilitytoperformtheseprocedures laparoscopicallydependsontheexpertiseoftheurologicsurgeon,but thereshouldprobablybealowthresholdforconversiontoanopen procedureinthecaseofaureteralinjury.
RECOMMENDEDREFERENCESAND READINGS
AdamMA,LeeLM,KimJ,etal.Alvimopanprovidesadditionalimprovementinoutcomesand
costsavingsinenhancedrecoverycolorectalsurgery.AnnSurg2016;264(1):141–6. AimaqR,AkopianG,KaufmanHS.Surgicalsiteinfectionratesinlaparoscopicversusopen
colorectalsurgery.AmSurg2011;77(10):1290–4. AquinaCT,BecerraAZ,ProbstCP,etal.Patientswithadhesivesmallbowelobstructionshouldbe
primarilymanagedbyasurgicalteam.AnnSurg2016;264(3):437–47. BattersbyNJ,JuulT,ChristensenP,etal.Predictingtheriskofbowel-relatedquality-of-life
impairmentafterrestorativeresectionforrectalcancer:amulticentercross-sectionalstudy.
DisColonRectum2016;59(4):270–80. BonjerHJ,DeijenCL,HaglindE;COLORIIStudyGroup.Arandomizedtrialoflaparoscopic
versusopensurgeryforrectalcancer.NEnglJMed2015;372(14):1324–32. FleshmanJ,BrandaM,SargentDJ,etal.Effectoflaparoscopic-assistedresectionvsopen
resectionofstageIIorIIIrectalcanceronpathologicoutcomes:theACOSOGZ6051
randomizedclinicaltrial.JAMA2015;314(13):1346–55. GuillouPJ,DarziA,MonsonJR.Experiencewithlaparoscopiccolorectalsurgeryformalignant
disease.SurgOncol1993;2Suppl1:43–9. GuillouPJ,QuirkeP,ThorpeH,etal.Short-termendpointsofconventionalversuslaparoscopic-
assistedsurgeryinpatientswithcolorectalcancer(MRCCLASICCtrial):multicentre,
randomisedcontrolledtrial.Lancet2005;365(9472):1718–26. GustafssonUO,OppelstrupH,ThorellA,NygrenJ,LjungqvistO.AdherencetotheERASprotocol
isassociatedwith5-yearsurvivalaftercolorectalcancersurgery:aretrospectivecohortstudy.
WorldJSurg2016;40(7):1741–7. HuaL,WangC,YaoK,ZhangJ,ChenJ,MaW.Istheincidenceofpostoperativeanastomotic
leakagedifferentbetweenlaparoscopicandopentotalmesorectalexcisioninpatientswith
rectalcancer?Ameta-analysisbasedonrandomizedcontrolledtrialsandcontrolledclinical
trials.JCancerResTher2014;10Suppl:272–5. JeongSY,ParkJW,NamBH,etal.Openversuslaparoscopicsurgeryformid-rectalorlow-rectal
cancerafterneoadjuvantchemoradiotherapy(COREANtrial):survivaloutcomesofanopen-
label,non-inferiority,randomisedcontrolledtrial.LancetOncol2014;15(7):767–74. KangSB,ParkJS,KimDW,LeeTG.Intraoperativetechnicaldifficultyduringlaparoscopy-
assistedsurgeryasaprognosticfactorforcolorectalcancer.DisColonRectum
2010;53(10):1400–8. KeenanJE,SpeicherPJ,ThackerJK,WalterM,KuchibhatlaM,MantyhCR.Thepreventive
surgicalsiteinfectionbundleincolorectalsurgery:aneffectiveapproachtosurgicalsite
infectionreductionandhealthcarecostsavings.JAMASurg2014;149(10):1045–52. LloydGM,KirbyR,HemingwayDM,KeaneFB,MillerAS,NearyP.TheRAPIDprotocolenhances
patientrecoveryafterbothlaparoscopicandopencolorectalresections.SurgEndosc
2010;24(6):1434–9.
MillerTE,ThackerJK,WhiteWD,etal.Reducedlengthofhospitalstayincolorectalsurgeryafter
implementationofanenhancedrecoveryprotocol.AnesthAnalg2014;118(5):1052–61. NygrenJ,ThackerJ,CarliF,etal.Guidelinesforperioperativecareinelectiverectal/pelvic
surgery:EnhancedRecoveryAfterSurgery(ERAS((R)))Societyrecommendations.WorldJ
Surg2013;37(2):285–305. ScarboroughJE,MantyhCR,SunZ,MigalyJ.Combinedmechanicalandoralantibioticbowel
preparationreducesincisionalsurgicalsiteinfectionandanastomoticleakratesafterelective
colorectalresection:ananalysisofcolectomy-targetedACSNSQIP.AnnSurg
2015;262(2):331–7. StevensonAR,SolomonMJ,LumleyJW,etal.Effectoflaparoscopic-assistedresectionvsopen
resectiononpathologicaloutcomesinrectalcancer:theALaCaRTrandomizedclinicaltrial.
JAMA2015;314(13):1356–63. SunZ,KimJ,AdamMA,etal.Minimallyinvasiveversusopenlowanteriorresection:equivalent
survivalinanationalanalysisof14,033patientswithrectalcancer.AnnSurg
2016;263(6):1152–8. VargasGM,SieloffEP,ParmarAD,TamirisaNP,MehtaHB,RiallTS.Laparoscopydecreases
complicationsforobesepatientsundergoingelectiverectalsurgery.SurgEndosc
2016;30(5):1826–32.
Chapter15
LaparoscopicLowAnterior ResectionwithTransanal AnastomosisorColonicJ­PouchCreation
W.ConanMustainandSharonL.Stein

INDICATIONS/CONTRAINDICATIONS

Chapter14reviewedthetechniqueformultiportlaparoscopiclow
anteriorresection(LAR).Thischapteremphasizestechniquesinvolvinga verylowrectalresectionrequiringcreationofacoloanalanastomosis, definedasanastomosisbetweenthecolonandthesurgicalanalcanal. Thesurgicalanalcanalisdefinedasthetissuebetweenthetopofthe anorectalringandthedentateline.VirtuallyallLARsinvolvea “transanal”anastomosis,typicallyadouble-stapledcolorectal anastomosiswithatransanallyintroducedcircularstapler.However, whenconstructingananastomosisatthelevelofthesurgicalanalcanal, particularconsiderationmustbegiventothemethodofrectal transection,theconfigurationofthecolonicanastomosis,andthe techniqueusedtocreatetheanastomosis.Thischapterdescribesvarious transanalsurgicaltechniquesandcolonicreservoirsthatmaybeusedin combinationwithlaparoscopicproctectomyforpreservationofintestinal continuityafterresectionofthedistalrectum.
ThemostcommonindicationforlaparoscopicLARwithcoloanal anastomosisiscancerofthedistalrectum.Occasionally,benign conditionssuchasrectovaginalorrectourethralfistula,ortechnical complicationssuchasstaplemisfiringmayrequiretheuseofacoloanal anastomosistoavoidpermanentcolostomy.Standardtreatmentfor rectalcancerinvadingbeyondthesubmucosaisenblocresectionofthe rectumandmesorectumwithnegativedistalandradialmargins. Improvedunderstandingoftumorbiologyhasledtoadecreased emphasisondistalmargin,from5to1–2cm,andanincreased appreciationoftheimportanceofthecircumferentialradialmarginwith regardtolocalrecurrence.Thisunderstandinghasenabledsurgeonsto
preserveintestinalcontinuityinallbutthemostdistalrectalcancers whileachievingsatisfactoryoncologicoutcomes.Resectionsofthisnature requiretechnicalexpertiseandtheabilitytoemploytechniquesbeyond theconventionaldouble-stapled,end-to-endcolorectalanastomosis.
TheprimaryreasontoemploytransanaltechniquesduringLARisthe inabilitytotransabdominallydividetherectumandthemesorectum. Thislimitationmaybesecondarytotechnicaldifficultiesand/or oncologicconsiderations.Technically,thespaceinthepelvisislimited andthepelvisdistallybecomesmorenarrow(Fig.15-1).Asdissection continuesdeepinthepelvis,theangleofinstrumentationbecomes paralleltotherectuminthepelvis.Whenchoosingtotransectthe mesorectumorrectum,theidealanglefortransectionisperpendicularto therectum.Limitedspaceinthepelvismayrenderthisdifficultor impossible.Techniquestoaccommodatethisincludeanterior-to­posteriorstapling,aswellasnewertransanaltotalmesorectaltechniques, whichmodifyanglesandaddresspriorlimitations.
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FIGURE15-1Demonstrationofthe(A)female
(gynecoid)versus(B)male(android)pelvis.Differences includeangleofpubissymphysis,sacraltilt,andthe sizeofthepelvicoutlet.Theseskeletaldifferences requireadjustmentsduringlaparoscopicsurgeryto facilitateaccessdeepinthepelvisforanorectal dissection,firingofstaplers,andcreationof anastomosis.
Inaddition,clearoncologicmarginsarevitaltoasuccessfuloperation. Whendistaltumorsabutorinvadetheupperaspectsoftheanorectalring orinternalsphincter,transanalresectionofaportionoftheinternal
sphinctermayberequiredtoobtainadequateradialmarginswhile preservingbowelcontinuity.Ahand-sewnanastomosisistypically requiredaftermucosectomyortranssphinctericresection.Itisgenerally acceptedthatastapledanastomosisispreferablewhenpossible,because oftime,simplicity,andlikelysuperiorfunctionalresults.Studieshave shownlowerratesofanastomoticstrictureanddecreasedseepageafter stapledanastomosiswhencomparedtohand-sewncoloanalanastomosis.
Regardlessofthetechniqueofanastomosis,theproximalcolonic segmentmaybeconfiguredendtoend,sidetoend,ormaybefashioned intoareservoirbycreationofacolonicJ-pouchoratransverse coloplasty.Althoughthedecisiontotransecttheboweltransanallyis mostoftendictatedbytheanatomy,theconfigurationoftheproximal colonicsegmentisgenerallyatthesurgeon’sdiscretion.Inadequate coloniclength,abulkymesocolon,oranarrowpelvismaypreclude creationofacolonicJ-pouch.ThecolonicJ-pouchcanbeconstructed throughatransabdominalincision,includingtheeventualloopileostomy site,orthroughtheanus.Afteranyrectalresection,thereisanexpected alterationofbowelfunctionbecausethecolonicportionofthe anastomosislacksthecompliance,contractility,anddistensibilityofthe normalrectum.Insomepatients,thischangemayresultinlife-altering dysfunctionbecauseoffrequentstools,urgency,seepage,or incontinence.Whenperformingverylowanastomoses,thecreationofa colonicreservoirwillimprovecomplianceofthepre-anastomotic segmentandleadtobetterfunctionalresults,particularlyduringthefirst yearaftersurgery.Severalrandomizedtrialsandmeta-analysessupport thenotionthatacolonicreservoiror“neorectum”leadstobetterearly functionalresultsthanastraightend-to-endcoloanalanastomosis.
ContraindicationstoLARandlaparoscopicsurgery,ingeneral,are describedinpreviouschaptersandareidenticalforlaparoscopic proctectomywithcoloanalanastomosis.Verydistalrectalresectionscan betechnicallychallengingregardlessoftheoperativeapproach,and anatomicfactorssuchasobesity,anarrowpelvis,prostatichypertrophy, orpriorpelvicsurgeryincreasethedegreeofdifficulty.Whenanyorallof thesefactorsarepresent,thesurgeonmustberealisticaboutthe likelihoodofcompletingthepelvicdissectionsafelywithlaparoscopy. Whendealingwithrectalcancer,asuccessfuloncologicoutcometakes priorityovertheshort-termbenefitsofminimallyinvasivesurgery.In somesituations,ahybridapproachmaybeused,wheretheabdominal portionofthecaseisdonelaparoscopicallyandthepelvicportion throughaninfraumbilicalmidlineorPfannenstielincision.Anecdotally, intheauthors’experience,theuseofatransverselinearstapler,suchas thePI30-3.5(Medtronic,Minneapolis,MN)ortheCONTOURcurved cutterstapler(EthiconEndo-Surgery,IncCincinnati,OH),applied throughamidlineorPfannenstielincisionwithmaximalupwardpullon