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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_861_Библиотеки_им_академика_М_И_Перельмана.pdf
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- •Dedication
- •Contributors
- •Foreword
- •Preface
- •Contents
- •Indications/Contraindications
- •Surgery
- •Conclusion
- •Indications/Contraindications
- •Complications
- •Results
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Surgery
- •Complications
- •Results
- •Conclusion
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Surgery
- •Conclusions
- •Surgery
- •Indications
- •Surgery
- •Complications
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications/Contraindications
- •Surgery
- •Outcomes
- •Complications
- •Indications/Contraindications
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Indications
- •Contraindications
- •Surgery
- •Complications
- •Conclusion
- •Indications/Contraindications
- •Surgery
- •Complications
- •Cost
- •Results
- •Conclusions
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Surgery
- •Complications
- •Results
- •Conclusions
- •Introduction
- •Conclusions
- •Introduction
- •Indications/Contraindications
- •Surgery

COMPLICATIONS
SurgicalSiteInfections/AnastomoticLeak
Despiteeffortstoreducetheirincidence,SSIsremaincommonfollowing
colonandrectalresection,occurringinupto20%ofcases.Overall,the
incidenceSSIsdoesappeartobelowerfollowinglaparoscopiccolorectal
resection.Areviewofover16,000laparoscopicandopencolonresections
includedintheAmericanCollegeofSurgeonsNationalSurgicalQuality
ImprovementProgram(ACS-NSQIP)databaserevealeda15.7%
incidenceofSSIintheopengroupcomparedto9.4%inthelaparoscopic
group(P<0.00001).AtDUMC,theauthorsinstituteapreventativeSSI
bundleforallopenandlaparoscopiccolonandrectalresections,which
includesapreoperativechlorhexidineshower,mechanicalbowel
preparationwithoralantibiotics,IVertapenem1hourbeforetheincision
ismade,chlorhexidineskinpreparation,useofawoundprotector,gown
andglovechangesbeforefascialclosure,andadedicatedclosure
instrumenttray.UseofthispreventativeSSIbundlehasdecreasedthe
incidenceofsuperficialSSIinourinstitutionfrom19.3%before
implementationto5.7%followingimplementation(Table14-2).
TABLE14-2 ManagementofComplicationsFollowing
LaparoscopicLowAnteriorResection
Complication Management
Lowanterior
resection
syndrome
(LARS)
Preoperative
Postoperative
ConsiderationofcolonicJ-pouch,transverse
coloplastypouch,end-to-sidecolorectal
anastomosis
Bulkinglaxatives
Pelvicfloorstrengtheningexercises
Antimotilityagents
Sacralnervestimulation(SNS)
Biofeedback
Retrograderectalirrigation
Conversiontoastomaforsevere,refractory
cases
Anastomotic
leak
Preoperative
Postoperative
Considerdivertingloopileostomy(DLI)
followingpreoperativechemoradiation
and/orlowcoloanalanastomosis(<5cm
fromanalverge)tolimitmorbiditysecondary
toanastomoticleak

Basedonseverityofclinicalpresentation:
Nontoxic,hemodynamicallystable,no
peritonitis:
IVantibiotics±percutaneousdrainageof
intra-abdominalcollection
Diffuseperitonitis,hemodynamicinstability:
Laparoscopy/laparotomywithdiversionof
anastomosiswithDLI,drainage
Smallbowel
obstruction
Adhesive
Secondaryto
suspectedvolvulus
ofDLI
NPO,nasogastrictubedecompression;
Operativemanagementforfailuretoresolve
obstructionordevelopmentofperitoneal
signs
Promptlaparoscopy/laparotomy
Ureteralinjury
Preoperative
Postoperative
Consideruseoflightedureteralstents
Intraoperativeurologicalconsultation
Laparoscopicrepairvs.conversiontoopen
procedurebasedonavailableexpertise
Ureteroneocystostomyvs.spatulationand
primaryrepairoverastentversus
ureteroureterostomybasedonlevelofinjury
Anastomoticleakisoneofthemostdevastatingcomplicationsof
restorativerectalresectionandisassociatedwithconsiderablemorbidity
andmortalityaswellasincreasedLOSandhealthcarecosts.The
laparoscopicapproachtoTMEandrestorativerectalresectiondoesnot
appeartoincreasetheincidenceofpostoperativeanastomoticleak.A
recentmeta-analysisincludingsixrandomizedcontrolledtrialsdidnot
findanysignificantdifferenceintheincidenceofpostoperative
anastomoticleakbetweenopenandlaparoscopicLAR.Theauthors
utilizemechanicalbowelpreparationwithPOantibioticsonallLARs
basedonastudyfromtheauthors’institutionofNSQIPdatathatfound
theincidenceofanastomoticleaktobesignificantlylowerinpatients
withapreoperativebowelprepcomparedtothosewithnobowelprep
(2.8%vs.5.7%).TheauthorsalsofrequentlyutilizeDLIforpatients
undergoingcoloanalanastomosis,particularlyafterpreoperative
chemoradiation.AlthoughtheissueofwhetherDLIreducestheincidence
ofanastomoticleaksremainscontroversial,itseemscleartheDLIlessens
theclinicalseverityofanastomoticleakwhenitoccurs.Theevaluation
andmanagementofanastomoticleakagedoesnotdifferbetween
laparoscopicandopenapproachesandhasbeenwelldescribed
elsewhere.OptionsmayincludeIVantibioticsalone,CT-guided
percutaneousdrainageofpelvicfluidcollections,andlaparoscopicDLIif

fecaldiversionisrequired.
SmallBowelObstruction
Smallbowelobstruction(SBO)isafrequentcomplicationfollowing
majorabdominalsurgeryincludingcolonandrectalresection.The
incidenceisprobablyhigherinpatientswhohaveaDLIsecondaryto
obstructionattributabletotheostomy.Arecentstudyincludingover
69,000patientsfromastateregistrydemonstratedthattheincidenceof
SBOwassignificantlylowerinpatientsfollowinglaparoscopiccolorectal
resectioncomparedtothatinpatientswhounderwentopenresection.
ThemanagementofSBOfollowinglaparoscopicLARisthesameasthat
forpostoperativeSBOingeneral,mostofwhichcanbemanagedwith
nasogastrictubedecompressionandexpectantmanagement.Inthecase
ofSBOfelttobeduetothesmallbowelwrappingaroundaloop
ileostomy,promptoperativemanagementisindicated.
p.108
p.109
ComplicationsRelatedtoDivertingLoopIleostomy
DLIisoftenperformedduringlaparoscopicLARasatemporaryfecal
diversionforadistalcolorectal/coloanalanastomosis,particularlyafter
preoperativechemoradiationtherapy.Thereisconflictingevidence
regardingwhetheraDLIreducestheincidenceofanastomoticleak;
however,aDLIlikelydecreasesthemorbidityandmortalityof
anastomoticleakwhenitoccurs.Thisbenefitmustbecarefullyweighed
againstthemorbidityandmortalityofanileostomy,includingthe
potentialfordehydrationandacutekidneyinjury,difficultieswith
pouching,leakageresultinginsignificantskindamage,prolapse,
parastomalhernia,andSBO.Inaddition,thepotentialmorbidityof
ileostomyreversalmustalsobeconsidered.Despitetheabilitytoclose
mostileostomieswithoutalaparotomy,theprocedureisnottrivialandis
associatedwithareportedmorbidityof17%,a0.4–0.6%mortality,a4%
incidenceofconversiontolaparotomy,a7–15%incidenceofSBO,anda
2%incidenceofanastomoticleak.
UreteralInjury
Fortunately,injurytotheureterduringlaparoscopicrectalresectionis
uncommon,occurringin1of240(0.4%)patientsundergoing
laparoscopyintheACOSOGZ6501trial.Theuseoflightedureteralstents
duringlaparoscopiccasesmayfacilitateintraoperativeidentificationof

theureters,helpavoidinjurytotheureters,andaidinprompt
recognitionofureteralinjuries.Theabilitytocontinuallyidentifythe
ureteralongitsentirecourseundoubtedlyallowsthedissectionto
confidentlyandefficientlyproceed.Itisimportanttoensurethattheleft
ureterisclearlyidentifiedbeforedivisionoftheprimaryvascularpedicle
(IMAorsuperiorrectalartery)withanendo-GIAstaplerorenergy
device.Anotherpotentialpointatwhichtheuretersareatriskforinjury
isthepointwheretheycrossthepelvicbrim.Managementofureteral
injuryhasbeenwelldescribedelsewhereandoptionsinclude
ureteroneocystostomy,spatulationandprimaryrepairoverastent,and
ureteroureterostomy.Thechoiceofrepairdependsonthelevelatwhich
theinjuryoccurs.Theabilitytoperformtheseprocedures
laparoscopicallydependsontheexpertiseoftheurologicsurgeon,but
thereshouldprobablybealowthresholdforconversiontoanopen
procedureinthecaseofaureteralinjury.

RECOMMENDEDREFERENCESAND
READINGS
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costsavingsinenhancedrecoverycolorectalsurgery.AnnSurg2016;264(1):141–6.
AimaqR,AkopianG,KaufmanHS.Surgicalsiteinfectionratesinlaparoscopicversusopen
colorectalsurgery.AmSurg2011;77(10):1290–4.
AquinaCT,BecerraAZ,ProbstCP,etal.Patientswithadhesivesmallbowelobstructionshouldbe
primarilymanagedbyasurgicalteam.AnnSurg2016;264(3):437–47.
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KangSB,ParkJS,KimDW,LeeTG.Intraoperativetechnicaldifficultyduringlaparoscopy-
assistedsurgeryasaprognosticfactorforcolorectalcancer.DisColonRectum
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KeenanJE,SpeicherPJ,ThackerJK,WalterM,KuchibhatlaM,MantyhCR.Thepreventive
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LloydGM,KirbyR,HemingwayDM,KeaneFB,MillerAS,NearyP.TheRAPIDprotocolenhances
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Chapter15

LaparoscopicLowAnterior
ResectionwithTransanal
AnastomosisorColonicJPouchCreation
W.ConanMustainandSharonL.Stein
INDICATIONS/CONTRAINDICATIONS
Chapter14reviewedthetechniqueformultiportlaparoscopiclow
anteriorresection(LAR).Thischapteremphasizestechniquesinvolvinga
verylowrectalresectionrequiringcreationofacoloanalanastomosis,
definedasanastomosisbetweenthecolonandthesurgicalanalcanal.
Thesurgicalanalcanalisdefinedasthetissuebetweenthetopofthe
anorectalringandthedentateline.VirtuallyallLARsinvolvea
“transanal”anastomosis,typicallyadouble-stapledcolorectal
anastomosiswithatransanallyintroducedcircularstapler.However,
whenconstructingananastomosisatthelevelofthesurgicalanalcanal,
particularconsiderationmustbegiventothemethodofrectal
transection,theconfigurationofthecolonicanastomosis,andthe
techniqueusedtocreatetheanastomosis.Thischapterdescribesvarious
transanalsurgicaltechniquesandcolonicreservoirsthatmaybeusedin
combinationwithlaparoscopicproctectomyforpreservationofintestinal
continuityafterresectionofthedistalrectum.
ThemostcommonindicationforlaparoscopicLARwithcoloanal
anastomosisiscancerofthedistalrectum.Occasionally,benign
conditionssuchasrectovaginalorrectourethralfistula,ortechnical
complicationssuchasstaplemisfiringmayrequiretheuseofacoloanal
anastomosistoavoidpermanentcolostomy.Standardtreatmentfor
rectalcancerinvadingbeyondthesubmucosaisenblocresectionofthe
rectumandmesorectumwithnegativedistalandradialmargins.
Improvedunderstandingoftumorbiologyhasledtoadecreased
emphasisondistalmargin,from5to1–2cm,andanincreased
appreciationoftheimportanceofthecircumferentialradialmarginwith
regardtolocalrecurrence.Thisunderstandinghasenabledsurgeonsto

preserveintestinalcontinuityinallbutthemostdistalrectalcancers
whileachievingsatisfactoryoncologicoutcomes.Resectionsofthisnature
requiretechnicalexpertiseandtheabilitytoemploytechniquesbeyond
theconventionaldouble-stapled,end-to-endcolorectalanastomosis.
TheprimaryreasontoemploytransanaltechniquesduringLARisthe
inabilitytotransabdominallydividetherectumandthemesorectum.
Thislimitationmaybesecondarytotechnicaldifficultiesand/or
oncologicconsiderations.Technically,thespaceinthepelvisislimited
andthepelvisdistallybecomesmorenarrow(Fig.15-1).Asdissection
continuesdeepinthepelvis,theangleofinstrumentationbecomes
paralleltotherectuminthepelvis.Whenchoosingtotransectthe
mesorectumorrectum,theidealanglefortransectionisperpendicularto
therectum.Limitedspaceinthepelvismayrenderthisdifficultor
impossible.Techniquestoaccommodatethisincludeanterior-toposteriorstapling,aswellasnewertransanaltotalmesorectaltechniques,
whichmodifyanglesandaddresspriorlimitations.
p.111
p.112
FIGURE15-1Demonstrationofthe(A)female
(gynecoid)versus(B)male(android)pelvis.Differences
includeangleofpubissymphysis,sacraltilt,andthe
sizeofthepelvicoutlet.Theseskeletaldifferences
requireadjustmentsduringlaparoscopicsurgeryto
facilitateaccessdeepinthepelvisforanorectal
dissection,firingofstaplers,andcreationof
anastomosis.
Inaddition,clearoncologicmarginsarevitaltoasuccessfuloperation.
Whendistaltumorsabutorinvadetheupperaspectsoftheanorectalring
orinternalsphincter,transanalresectionofaportionoftheinternal

sphinctermayberequiredtoobtainadequateradialmarginswhile
preservingbowelcontinuity.Ahand-sewnanastomosisistypically
requiredaftermucosectomyortranssphinctericresection.Itisgenerally
acceptedthatastapledanastomosisispreferablewhenpossible,because
oftime,simplicity,andlikelysuperiorfunctionalresults.Studieshave
shownlowerratesofanastomoticstrictureanddecreasedseepageafter
stapledanastomosiswhencomparedtohand-sewncoloanalanastomosis.
Regardlessofthetechniqueofanastomosis,theproximalcolonic
segmentmaybeconfiguredendtoend,sidetoend,ormaybefashioned
intoareservoirbycreationofacolonicJ-pouchoratransverse
coloplasty.Althoughthedecisiontotransecttheboweltransanallyis
mostoftendictatedbytheanatomy,theconfigurationoftheproximal
colonicsegmentisgenerallyatthesurgeon’sdiscretion.Inadequate
coloniclength,abulkymesocolon,oranarrowpelvismaypreclude
creationofacolonicJ-pouch.ThecolonicJ-pouchcanbeconstructed
throughatransabdominalincision,includingtheeventualloopileostomy
site,orthroughtheanus.Afteranyrectalresection,thereisanexpected
alterationofbowelfunctionbecausethecolonicportionofthe
anastomosislacksthecompliance,contractility,anddistensibilityofthe
normalrectum.Insomepatients,thischangemayresultinlife-altering
dysfunctionbecauseoffrequentstools,urgency,seepage,or
incontinence.Whenperformingverylowanastomoses,thecreationofa
colonicreservoirwillimprovecomplianceofthepre-anastomotic
segmentandleadtobetterfunctionalresults,particularlyduringthefirst
yearaftersurgery.Severalrandomizedtrialsandmeta-analysessupport
thenotionthatacolonicreservoiror“neorectum”leadstobetterearly
functionalresultsthanastraightend-to-endcoloanalanastomosis.
ContraindicationstoLARandlaparoscopicsurgery,ingeneral,are
describedinpreviouschaptersandareidenticalforlaparoscopic
proctectomywithcoloanalanastomosis.Verydistalrectalresectionscan
betechnicallychallengingregardlessoftheoperativeapproach,and
anatomicfactorssuchasobesity,anarrowpelvis,prostatichypertrophy,
orpriorpelvicsurgeryincreasethedegreeofdifficulty.Whenanyorallof
thesefactorsarepresent,thesurgeonmustberealisticaboutthe
likelihoodofcompletingthepelvicdissectionsafelywithlaparoscopy.
Whendealingwithrectalcancer,asuccessfuloncologicoutcometakes
priorityovertheshort-termbenefitsofminimallyinvasivesurgery.In
somesituations,ahybridapproachmaybeused,wheretheabdominal
portionofthecaseisdonelaparoscopicallyandthepelvicportion
throughaninfraumbilicalmidlineorPfannenstielincision.Anecdotally,
intheauthors’experience,theuseofatransverselinearstapler,suchas
thePI30-3.5(Medtronic,Minneapolis,MN)ortheCONTOURcurved
cutterstapler(EthiconEndo-Surgery,IncCincinnati,OH),applied
throughamidlineorPfannenstielincisionwithmaximalupwardpullon
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