Добавил:
kiopkiopkiop18@yandex.ru t.me/Prokururor I Вовсе не секретарь, но почту проверяю Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:

Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5336_Библиотеки_им_академика_М_И_Перельмана

.pdf
Скачиваний:
0
Добавлен:
30.08.2026
Размер:
44 Мб
Скачать
156 Hartwig Schulz
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
East, Persia, and India (Fig. 3.1). Important principles here were the influences of light, air, nutrition, exercise, rest, regulated sleep, the balance of the body humors, and a bal­anced mind on human well-being.
“Let your food be your medicine and your medicine be your food.” This statement is attributed to the Greek physician Hippoc­rates of Kos (460–377 ). However, there were also some older natural healing methods that advocated this maxim, such as TCM and Ayurveda, the traditional Indian system of medicine. Ayurveda can be traced back at least 5000 years, and here, too, nu
­trition and aromatic herbs play a very im­portant role in health. Like most traditional systems of medicine, it has been developed and refined over thousands of years based on observation and experience. Ayurvedic therapies have been practiced for thousands of years, long before there were placebo­controlled experiments.
In Ayurveda, as in the other Asian trad­itional medical systems, foods, medicinal herbs, and other substances (including min
­eral and animal substances) are also con­sidered as potential “remedies”. In contrast to modern pharmacy, Ayurveda thus basic­ally makes no distinction between food and medicine, both are considered as dravya (“substance”). If a “substance” (and this in­cludes also food) is to be used for Ayurveda, it must be able to be evaluated according to the special Ayurvedic principles. In contrast to Western medicine, in Ayurveda and also in other traditional Eastern medical systems (e.g. TCM, TPM/TIM), a specific herbal mix­ture is developed for the individual person that best suits his or her “type”. The classifi­cation according to the three doshas is gener­ally reflected in the individual diet and the other Ayurvedic applications. Furthermore, food is usually cooked so that the body can better absorb the individual active plant components; raw vegetables are rarely con­sumed. The individual herbal raw materials such as cloves (S. aromaticum), turmeric (Curcuma longa), ginger (Zingiber officinale), cardamom (Elettaria cardamomum), corian­der (C. sativum), cumin (C. cyminum), nut­meg (Myristica fragrans), pepper (P. nigrum and Piper longum), saffron (C. sativus), and
cinnamon (C. verum) are very often attrib­uted a spiritual effect on body and mind. In Europe, long pepper (P. longum), as the first introduced species of the genus Piper, has been more or less neglected. This pepper species originates from India and is still widely cultivated there today as a holy medi­cinal plant in the context of Ayurvedic medi­cine. In contrast to black pepper (P. nigrum), which is mainly used in Europe today, long pepper’s aroma shows sweet, minty, and sometimes even chocolate-like aspects in addition to the pungency (mainly caused by the alkaloid piperine) that has also given this plant species the popular name “choc­olate pepper” (Zaveri etal., 2010).
It is not surprising that the list of medi­cinal and aromatic plants species used in Ayurvedic medicine corresponds very well with that mentioned by Avicenna in his book Canon of Medicine. In ancient times, there was already an extensive commercial trade between India, China, Arabia, and Per­sia. The so-called “Silk Road”, which already existed during Roman times, not only sup­ported the trade with various goods but also contributed significantly to the exchange of medical knowledge and ideas between these countries.
Even today, Ayurveda still represents an important medical system in India, Paki­stan, Nepal, and Sri Lanka, which in the past has also partly influenced the medical sys­tems in Tibet, Myanmar, and Malaysia. An­other famous Eastern health system is TCM, which has also been established in Korea and Japan and spread south to Thailand, Laos, and Vietnam, where it is comple­mented by both Ayurveda and Unani, the ITM system used mainly in South Asian countries with significant Muslim popula­tions. ITM has its roots in the Hippocratic theory of the humors adopted from ancient Greece. The common basic concept of all these medical systems is that there exists an underlying life energy called prone in San­skrit, chi in China, and ki in Japan. In gen­eral, the aim is to combine physical, mental, and spiritual aspects and in this way to pre­vent diseases and strengthen the body’s de­fences. In Ayurvedic medicine, illness is generally attributed to mental or physical
Relationships 157
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
imbalances. The individual therapy ap­proach is generally based on the three Ayur­vedic doshas, which determine the mental balance and are assigned to the five elem­ents: space, water, earth, air, and fire. In this context, Vā ta , consisting of air and space, is considered the life energy; kampha, related to earth and water, on the other hand, is re­sponsible for the structure of the body, its growth, and flexibility. The dosha pitta, as­signed to fire and water, is made responsible for all biochemical processes in the human body.
In a similar way, TPM/TIM too is based
on the concept of the four humors: phlegm (balgham), blood (dam), yellow bile (safrā’), and black bile (saudā’). This concept mainly refers to the theories developed by Rhazes and Avicenna.
Kampo medicine is the original trad­itional system of medicine in Japan. Here, no distinction is made between Western and Kampo medicine, and both systems are therefore subject to the same legal regula­tions today. Accordingly, the application for marketing authorization of ethical Kampo medicinal products follows the general noti­fication for medicinal products. In addition, applications for marketing authorization of ethical Kampo medicinal products should follow the Kampo-specific notification “Handling of ethical Kampo medicinal prod­ucts”. In general, the safety, efficacy, and quality of Kampo medicinal products are comprehensively ensured by the Japanese Pharmacopoeia, Good Manufacturing Prac­tice, Good Agricultural and Collection Prac­tice, Certificate of Marketing Authorization, Marketing Authorization Standard, and Pharmacovigilance.
Temperament is a key concept for understanding the fundamentals of trad­itional medicine, on the basis of which people are classified as healthy and sick. This principle plays an important role in de­termining ways to maintain health and also in treating diseases.
Increasingly, conventional medicine today is also placing more emphasis on treating the patient as an individual rather than the disease in general. Accordingly, nu­merous studies have already been conducted
to gain more knowledge regarding the rela­tionship between temperament and prote­omes in the human body (Jafari etal., 2014; Shirbeigi etal., 2017). Today, TPM/TIM is considered a rich and valuable source in the field of medical history to the point that in a period of history, it has been used as an im­portant educational reference even at vari­ous universities in European countries (Aciduman etal., 2009).
In Western medicine, too, “personalized medicine” has been gaining more attention again for several years. In line with the pre­sent spirit (zeitgeist) of increasing personal individualization, the challenge here is to achieve a maximum therapeutic efficacy for each patient while minimizing any possible side effects. In this context, especially high-throughput technologies and modern imaging techniques are used to gain a better understanding of the molecular processes involved in the development of various diseases.
Even before the collapse of advanced civilization in the Mediterranean region in the period from the 6th to the 8th century , Benedict of Nursia founded the first monastery of the Benedictine order on Monte Casino in southern Italy, which was later named after him. Benedictus founded the abbey of Montecassino in a temple of Apollo around the year  529. This abbey is still considered the original monastery of the Benedictine order (in Latin: Ordo Sancti Benedicti, OSB) which also provided the framework for monastic medicine. The monks and nuns drew on the medical know
­ledge of the ancient physicians and adopted the four-fluid doctrine, the so-called “hu­moral pathology”, as a basis. The basic rule for monastic life was given by the Latin motto ora et labora (“pray and work”), with the care of body and soul always in the fore
­ground. The Benedictine monks mainly healed sick people, and in this context felt responsible not only for the members of the order, but for anyone who came to them with a health problem.
This idea of placing mercy and charity above all other duties was considered revolu­tionary at that time, because in Greco­Roman culture weak and sick people were
158 Hartwig Schulz
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
regarded responsible for their own fate. Apart from Benedict, his friar Cassiodorus ( 490–580) was particularly committed to the development of monastic medicine. This work was not only focused on the study of the books handed down by Hippocrates, Di­oscorides, and Galen, but also placed par­ticular emphasis on the study of medicinal herbs and the development of new plant mixtures that could be used for various heal­ing purposes. Apart from the ancient books cited above, the monks referred mainly to the natural history book with the Latin name Naturalis historia written by Plinius and thus they created a medicinal compen­dium that was considered a standard work at that time.
Ancient civilizations contributed much to the development of phytotherapy by identifying and describing numerous spe­cies of medicinal plants. This knowledge of herbal raw materials thus formed the basis of medieval medicine. The revival of herbal medicine can be observed since the 6th cen­tury , when monasteries were established where gardens were planted to grow medi­cinal plants. Monastic schools were also founded, and monks expanded their know­ledge by studying and copying ancient books and prepared medicines of natural origin ac­cording to secret recipes, which were used to cure the sick. Although the Middle Ages is often regarded as a dark age, many achieve­ments of phytotherapy from this period have passed into history and are still used by people today.
The monks and nuns in the monasteries copied and interpreted the writings of Greek and Roman philosophers and physicians and were thus able to store and preserve the know­ledge passed down from antiquity in Europe. Monastery herb gardens typically followed the rules set down around  840 by Walah­frid Strabo, Benedictine monk, poet, and bot­anist. In his book, Liber de cultura hortorum, he described 24 medicinal plants, their charac­teristics, and individual application. The book became one of the most important botany books of the Early Middle Ages.
After the decline of the Imperium Roma- num (Roman Empire) medical development in Europe gained new impetus with the
Lorsch Pharmacopoeia (Lorscher Arzneibuch) in the middle of the 11th century .
In the High Middle Ages (11th and 12th centuries ), the first important writings of monastic medicine were created, such as the translations of the book Constantinus Af- ricanus in Salerno. Furthermore, the Bene­dictine nun Hildegard of Bingen ( 1098–1179) described 300 plant species in­cluding their individual medicinal applica­tions. Unfortunately, her Book of Secrets in
Nature and Creatures (Liber subtilitatum di­versarum naturarum creaturarum) was lost
after her death. About 150 years later, sev­eral manuscripts were retrieved and at­tempts were made to reassemble Hildegard’s original work, which was divided into two treatises, Physica and Causae et curae (Causes and Cures). The textbooks are mainly attrib­uted to Hildegard, although some sections may have been influenced by later revisions.
Until the 19th century , the humoral pathology developed in antiquity according to Hippocrates and the numerous writings of Galen remained predominant in medi­cinal treatments in both the Orient and Oc­cident. Accordingly, the balance of the four humors (eucrasia) was considered an im­portant prerequisite for health. Hildegard of Bingen was also influenced by the ancient teachings of humoral therapies, according to which mismanagement of the humors leads to disorders of body and mind. Therefore, a central message of Hildegard of Bingen’s medicine is the belief in the power of nature; a power that strives for balance.
The knowledge from the Near Eastern roots of monastic medicine and comprehen­sive visionary insights, shaped, among other things, the so-called “Hildegard medicine” that is still well known and appreciated in Europe of today. Hildegard of Bingen and the medicine of her time were practiced within the monastic community. Like most medieval medical cures, her practices were mainly guided by the principles described in the Bible. Today, monastic medicine is in­creasingly gaining influence in modern medicine and it is generally accepted that Hildegard of Bingen’s work was significantly influenced by the following four works (Baader, 1979):
Relationships 159
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
Physiologus, a book on natural history
written in Egypt in the 2nd century . is book of an unknown author was available in several translations, includ­ing Latin, around  700.
De materia medica by the Greek phys-
ician Dioscorides with descriptions of
about 500 medicinal plants recognized for medical treatment (Fig. 3.9). With regard to the cultivation of medi-
cinal plants, she beneted predomin­antly from the already mentioned Bene­dictine monk Walahfrid Strabo, whose famous work Hortulus (Garden) has
Fig. 3.9. Page from the Vienna Dioscorides codex (Codex medicus Graecus of the Austrian National Library, 6th century), an illustrated version of De materia medica (1st century AD), page 29v). (Public Domain, https://commons.wikimedia.org/w/index.php?curid=43449887.)
160 Hartwig Schulz
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
served as an important basis for horti­culture for centuries.
e herbal medicine traditions recog-
nized in the Middle Ages were generally known as “Macer Floridus” from the 11th century  and coincided with the development of Circa instans simplicibus medicinis (From the Simple Medicines), which was developed by Matthew Pla­tearius, the medieval physician of the Salerno Medical School.
After the Ottoman Empire’s advance into the Iberian Peninsula, Christianity benefited from Islam’s extensive knowledge of the natural sciences and medicine. In this context, the Toledo school of translators around Gerhard of Cremona ( 1134–
1187), who translated numerous Arabic writings into Latin, was of particular importance.
From around  1280 onward, the first German pharmacopoeia, written by Ortolf von Würzburg, a highly respected wound physician with an academic education, was used regionally until the end of the 16th century. It is characterized by a high level of expertise and can be described as a pioneer­ing act, as it was customary until then to write medical textbooks in Latin. He ad­dressed his textbook to fully trained practi­tioners, primarily wound physicians, and imparted to them profound knowledge about diagnosis, prognosis, and therapy. Or­tolf drew primarily on Salerno sources for his work, which was primarily based on 12th and 13th century sources, and he also used medical literature from Parma, Toledo, and Paris. Among the most important sources is the Compendium medicinae (Compendium of Medicine) written by Gilbertus Anglicus.
In these books, mentioned above, first influences of Oriental medicine can already be found, which at that time could already look back on a longer tradition. In the 14th and 15th centuries , increasingly compre­hensive herbal encyclopedias were pub­lished, which claimed to collect and disseminate the entire phytotherapeutic knowledge available in Europe at that time (Fuchs, 2001). These herbal records describing the use of medicinal plants thus represent in
a certain way the basis of today’s “European Pharmacopoeia”.
Especially in the Middle Ages, Galen’s teachings were favored over others and es­tablished the basis of medical knowledge at European universities until the 19th cen­tury (Schipperges and Durling, 1989). Fur­thermore, special attention should be also paid to the physician Ibn But lan (11th cen- tury ), who worked at the court in Bagh­dad and, as a Christian doctor, wrote many medical works. In his book entitled Taqwīm as   (Tabular Overview of Health, in-Sihhah Latin: Tacuina sanitatis in medicina), he teaches several health rules that are pre­sented in the form of a synoptic table work. This clear reference work for questions of a healthy lifestyle at that time attracted spe­cial attention in several European cities such as Vienna, Paris, and Rome. Later a Vien­nese edition of the Tacuina was produced in the 14th century , probably in Lombardy (Herr, 1988).
In the middle of the 15th century  a so-called Paris Tacuinum sanitatis evolved, including also several illustrations from Circa instans (Goehl, 2015) which were pre­sented in the tradition of the synoptic table work, created by Ibn Butlan. These manu­scripts, however, were not written for spe­cialists but more for the upper middle classes and nobility in Europe. Accordingly, the con­tent of this book is essentially based on an­cient and medieval humoral pathology and explains which foods and human states of mind (anger, joy, etc.) represent the four elements “dry”, “moist”, “cold”, and “warm” and for which people and in which regions they could be useful. The concept of humoral pathology assumes that the function of the human body is regulated by the four humors (blood, phlegm, yellow bile, and black bile) and only secondarily by its organs. It was as­sumed that humors correspond to the four elements “cold–warm” and “dry–humid”. Applying a specific selection of medicines and food raw materials, the doctors tried to restore the patient’s health as best as pos­sible by establishing a balance with special regard to the human body fluids and pri­mary elements (Table 3.1). Garlic, for ex­ample, is described in this context as “warm”
Relationships 161
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
pathology, developed by Ortolf on the basis of the four elements and several primary qualities. (According to Riha, 2017.)
Primary elements Warm/humid Warm/dry Cold/humid Cold/dry Elements Air Fire Water Soil Body fluids Blood Yellow bile Mucus Black bile Temperaments Sanguine type Choleric type Phlegmatic type Melancholiac Colors Red Yellow White Black Taste Sweet Bitter Salty Sour Time of day Morning Noon Night Evening Gender Man Woman Age Youth Adulthood Childhood Senility Organs, tissue Heart, liver,
muscles
Gall bladder Brain, stomach/gut, kidneys/
urinary bladder, fat
Spleen, bones,
tendons
and “dry”. In addition, the book states that garlic “produces pungent juices and is useful against scorpion and snake bites, as well as against worms”. Therefore, “garlic is espe­cially recommended for weakened natures and in cold regions”.
In the Middle Ages the manuscripts of Circa instans were widely circulated through­out Europe and were also translated into German and served as a model for later au­thors such as Adam Lonitzer ( 1528–
1568) when writing their pharmaceutical textbooks. Furthermore, it can be clearly seen that the chapter division refers to Dioscorides and the descriptions of the humoral pathology are based on Galen’s theories (Goehl, 2015).
The wound physician Ortolf von Baier­land (born in the first half of the 13th cen­tury) wrote a medical textbook around  1280 that was used regionally until the end of the 16th century.
Ortolf also focused on the model of medieval humoral pathology. He refers to this model particularly in the diagnosis and subsequent therapy. When examining his patients, Ortolf also oriented himself to cer­tain “leading symptoms”, which he assigned to the respective primary qualities (cold– warm and dry–damp, respectively) (Riha,
2017).
Philippus Aureolus Theophrastus Bom­bastus von Hohenheim, who called himself “Paracelsus” ( 1493–1541), occupied a special position. Until today, the myth of Paracelsus is very widespread, especially in
German-speaking countries. Especially, his well-known sentence “all things are poison and nothing is without poison; it is the dose alone that makes a thing not poison” re­mains unforgotten. Paracelsus created his own system of healing various diseases, which was based on alchemical medicine on the one hand and on empirical knowledge on the other. For example, he treated syph­ilis, which was widespread in the 16th cen­tury, with mercury and guaiac wood. During his lifetime, Paracelsus was known only to a few contemporaries, as hardly any of his writings were printed.
Herbal Medicinal Products as a
Source for Modern Evidence-Based
Medical Systems
Nowadays, more attention is again being paid to research related to plants used in traditional medicine, as they can be pro­duced comparatively cheaply and usually show no undesirable side effects. Spices and herbs such as garlic, mustard, cinnamon, cumin, cloves, thyme, basil, pepper, ginger, and rosemary have been used since ancient times as food additives, flavorings, and nat­ural preservatives. A number of spices also exhibit antimicrobial activity against nu­merous bacteria and fungi. Therefore, an increasing consumption of herbal medicines is observed worldwide, as they represent often a suitable alternative to the use of synthetic
162 Hartwig Schulz
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
drugs in the treatment of a number of health problems, including heart disease, diabetes, hypertension, and even certain types of cancer.
The use of herbs to treat various dis­eases is almost universal, particularly in nonindustrialized societies (DaSilva et al.,
2002). According to estimates of the WHO, about 80% of the population in some Asian and African countries currently apply herbal medicines in order to heal certain diseases. In the USA about 25% of modern medicines available on the market are de­rived from herbal plants and widely used in modern medicine. About 80% of the 120 active ingredients currently isolated from higher plants show a positive correlation between their modern therapeutic and traditional use (Fabricant and Farnsworth,
2001). It is estimated that at least 7000 ac­tive medicinal ingredients in the modern pharmacopoeia are derived from plants. Significant variations in plant properties with different soil conditions have been ob­served for many medicinal and aromatic plants (Carrubba and Scalenghe, 2012). The growing interest in medicinal plants can be also seen, among other things, in the significant increase in plant monographs in the European Pharmacopoeia (at present clearly more than 100).
Today, in the context of clinical re­search, evidence-based medicine (EBM) is generally considered the standard in the Western world. However, a few phytophar­maceuticals do not correspond to these spe­cifications, which is not surprising due to the individual underlying philosophy.
However, despite the enormous scientific successes of “modern medicine”, it should not be overlooked that many cultures on this earth gained extensive experience with medicinal plants over thousands of years and usually the doctors could successfully treat their patients. The isolation of individ­ual active substances from the individual medicinal plants must also be viewed critic­ally, since solvent extraction or steam distil­lation already may cause significant changes in the plant metabolite profile. The selection of the respective extraction solvent (e.g., n-hexane, ethanol, water, supercritical car­bon dioxide) already generates a selection according to the different polarities. How­ever, since the efficacy of herbal drugs often involves the complex interaction of individ­ual constituents, the isolated extraction of individual chemical groups (e.g., terpene hy­drocarbons, alkaloids, fats, sugars, amino acids) may sometimes reduce their pharma­cologic efficacy.
On the other hand, however, the use of single active ingredients and active ingredi­ent complexes isolated from the plant ma­trix has resulted in phytopharmaceuticals with high and reliable pharmaceutical effi­cacy. Undoubtedly, the very high number of plant secondary plant metabolites repre­sents a “treasure trove” for the development of future drugs. Searching for new valuable plant substances and active ingredient com­plexes, the so-called “omics” techniques available today (genomics, transcriptomics, proteomics, metabolomics) and intelligent biostatistical methods in particular will play a very important role.
Abdul-Jalil, T.Z. (2020) Rhus coriaria (sumac): a magical spice. In: Akram, M. and Shabir Ahmad, R. (eds)
Herbs and Spices. IntechOpen, London. DOI: 10.5772/intechopen.92676.
Aciduman, A., Er, U. and Belen, D. (2009) Peripheral nerve disorders and treatment strategies according to
Avicenna in his medical treatise, Canon of Medicine. Neurosurgery 64, 172–177. DOI: 10.1227/01. NEU.0000335779.27115.D3.
Ahmadipour, S., Ahmadipour, S., Mohsenzadeh, A. and Asadi-Samani, M. (2016) The importance of some
native medicinal plants of Iran effective on gastrointestinal disorders in children: a review. Der Pharma- cia Lettre 8, 61–66.
Alexiades, N.M. and Sheldon, J.E. (eds) (1996) Selected Guidelines for Ethnobotanical Research: A Field
Manual. New York Botanical Garden Press, New York.
References
Relationships 163
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
Amar, Z., Lev, E. and Serri, Y. (2014) On Ibn Juljul and the meaning and importance of the list of medicinal
substances not mentioned by Dioscorides. Journal of the Malaysian Branch of the Royal Asiatic Society 24(4), 529–555.
Amiri, M.S., Joharchi, M.R. and Yazdi, T.M.S. (2014) Ethno-medicinal plants used to cure jaundice by
traditional healers of Mashhad, Iran. Iranian Journal of Pharmaceutical Research 13, 157–162.
Anyinam, C. (1995) Ecology and ethnomedicine: exploring links between current environmental crisis and
indigenous medical practices, Social Science & Medicine 40(3), 321–329.
Ardekani, M.R.S., Rahimi, R., Javadi, B., Abdi, L. and Khanavi, M. (2011) Relationship between tempera-
ments of medicinal plants and their major chemical compounds. Journal of Traditional Chinese Medicine 31, 27–31. DOI: 10.1016/S0254-6272(11)60006-X.
Azizi, M.H. (2008) Gondishapur school of medicine: the most important medical center in antiquity.
Archives of Iranian Medicine 11, 116–119.
Azizi, M.H., Nayernouri, T. and Azizi, F. (2008) A brief history of the discovery of the circulation of blood in
the human body. Archives of Iranian Medicine 11, 229–234.
Baader, G. (1979) Naturwissenschaft und Medizin im 12. Jahrhundert und Hildegard von Bingen. Archiv für
mittelrheinische Kirchengeschichte 31, 33–54. Banerjee, M. (2002) Public policy on Ayurveda. Economic and Political Weekly 37, 1136–1146. Bauer, T. (1988) Das Pflanzenbuch des Abu Hanifa ad-Dinawari: Inhalt,Aufbau, Quellen. Otto Harrassowitz,
Wiesbaden, Germany. Bolens, L. (1977) L’agriculture hispano-arabe au Moyen Age. In: Handbuch der Orientalistik, Geschichte
der islamischen Länder, Band 6. E.J. Brill, Leiden, The Netherlands/Cologne, Germany, pp. 255–275. Bryan, C.P. (2021) The Papyrus Ebers: Ancient Egyptian Medicine. Translated from the German version.
Martino Fine Books, Eastford, Connecticut. Calvo, E. (2008) Encyclopaedia of the History of Science, Technology, and Medicine in Non-Western
Cultures. Springer, Dordrecht, The Netherlands. Cambra, L.M.A. (2001) An example of medical practice in al-Andalus: Treatise XIX of the Kita b al-tarsıf of
Abu  -l-Qasim al-Zahrawı. Dynamics 21, 73–91. Cárcer, L.F.A. (2001) Therapeutic use of aromatic substances in al-Andalus. Dynamics 21, 93–132. Carrubba, A. and Scalenghe, R. (2012) Scent of Mare Nostrum – medicinal and aromatic plants in Mediter-
ranean soils. Journal of the Science of Food and Agriculture 92, 1150–1170. Castleman, M. (2001) The New Healing Herbs: The Classic Guide to Nature’s Best Medicines Featuring
the Top 100 Time-Tested Herbs. Rodale, Emmaus, Pennsylvania. DaSilva, E.J., Baydoun, E. and Badran A. (2002) Biotechnology and the developing world. Electronic
Journal of Biotechnology 5(1), 1–2. DOI: 10.2225/vol5-issue1-fulltext-1. Defremery, C. and Sanguinetti, B.R. (1929) Ibn Bat  tuta:Travels in Asia and Africa. French translation of the
Arabic text edited for the first time in 1854. George Routledge & Sons Ltd, London. de Silva, T. (1997) Industrial utilization of medicinal plants in developing countries. In: Bodeker, G., Bhat,
K.K.S., Burley, J. and Vantomme, P. (eds) Medicinal Plants for Forest Conservation and Healthcare.
Non-Wood Forest Products No. 11. Food and Agriculture Organization of the United Nations, Rome,
pp. 34–44. de Vos, P. (2013) The “Prince of Medicine”: Yu ibn Ma
pharmaceutical tradition. Isis 104, 667–712. DOI: 10.1086/674940. Diller, H. (2021) Hippokrates/Die Heilkunst (aus dem Griechischen übersetzt). Reclams Universal-Biblio-
thek Nr. 19694. Philipp Reclam jun. Verlag GmbH, Ditzingen, Germany. Durant, W. (1950) The Age of Faith.A History of Medieval Civilization – Christian, Islamic, and Judaic – From
Constantine to Dante: A.D. 325–1300. Simon & Schuster, New York. Durling, R.J. (1989) Leonhart Fuchs and his Commentaries on Galen. Medizinhistorisches Journal 24,
42–47. Elgood, C. (1951) A Medical History of Persia. Cambridge University Press, Cambridge. Elgood, C. (1979) A Medical History of Persia and the Eastern Caliphate from the Earliest Times to the Year
A.D. APA-Philo Press, Amsterdam. Elgood, C. (1992) Iran Medical History and the Regions of Eastern Caliphate. Translated into Persian by F.
Baher. Amir Kabir Publications, Tehran, p. 22, 37. Emami, S.A. and Aghazari, F. (2011) Les Phanerogames Endemiques de la flore d’Iran. Tehran University
Publication, Tehran, p. VII. Emami, S.A., Iranshahi, M. and Iranshahi, M. (2017) Herbal Pharmacopoeia. Behnashr and Mashhad
University of Medical Sciences Publications, Mashhad, Iran, p. 28 (in Persian).
hanna sawayh and the foundations of the Western
164 Hartwig Schulz
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
Fabricant, D.S. and Farnsworth, N.R. (2001) The value of plants used in traditional medicine for drug
discovery. Environmental Health Perspectives 109, 69–75.
Fahd, T. (1993/1995) L’Agriculture Nabatéene. Translation into Arabic attributed to Abu Bakr Ahmad b.
Ali al-Kasd a ni, known as Ibn Wahshiya (4th–10th century), 2 vols, Damascus.
Fahd, T. (1996) Botany and agriculture. In: Rashed, R. (ed.) Encyclopedia of the History of Arabic Science,
Vol. 3. Routledge, London and New York, pp. 813–852.
Fallah-Hoseini, H., Fakhrzadeh, H., Larijani, B. and Shikhsamani, A. (2006) Review of anti-diabetic
medicinal plants used in traditional medicine. Journal of Medicinal Plants 5, 1–8. al-Faruqi, I.R. and al-Faruqi, L.L. (1986) The Cultural Atlas of Islam. Prentice-Hall. New York. Fuchs, L. (2001) Das Kräuterbuch von 1543 (Faksimile-Druck). Taschen GmbH, Cologne, Germany. Gha  fiqı, M., Hebraeus, B., Meyerhof, M. and Subhı, J. (1932–1940) The Abridged Version of “The Book of
Simple Drugs” of Ahmad ibn Muhammad al-Gha
Goehl, K. (2015) Das Circa Instans. Die erste große Drogenkunde des Abendlandes. Deutscher Wissen-
schafts-Verlag, Baden-Baden, Germany. Hamidullah, M. (1973) Le Dictionnaire botanique d’Abu hanifa al-Dinawari. Compiled and translated
according to the citations of later works, edited by the Institut Francais d’Archéologie Orientale, Cairo. Heinrich, M. (2000) Ethnobotany and its role in drug development. Phytotherapy Research 14, 479–488. Herr, M. (1988) Translation of the book: Ibn Butlan, Ibn Dschezla: Schachtafelen der Gesundheyt. Edition
Straßburg (Hans Schott) 1533, with an epilogue by Marlit Leber and Elfriede Starke, Weinheim,
Germany. Hitti, P.K. (1937) History of the Arabs. Revised 10th edn, Palgrave Macmillan, New York, 2002. Ibrar, M., Hussain, F. and Sultan, A. (2007) Ethnobotanical studies on plant resources of Ranyal hills, district
Shangla, Pakistan. Pakistan Journal of Botany 39, 329–337. Jafari, M., Rezadoost, H., Karimi, M., Mirzaie, M., Rezaie-Tavirani, M. etal. (2014) Proteomics and trad-
itional medicine: new aspect in explanation of temperaments. Forschende Komplementärmedizin 21,
250–253. DOI: 10.1159/000366118. Jastrow, M. (1914) Medicine of the Babylonians and Assyrians. Proceedings of the Royal Society of Medi-
cine 7 (Sect. Hist. Med.), 109–176. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2003546/
(accessed 23 March 2023). Javadi, B. and Emami, S.A. (2015) Avicenna’s contribution to mechanisms of cardiovascular drugs. Iranian
Journal of Basic Medical Sciences 18, 721–722. Jivad, N., Bahmani, M. and Asadi-Samani, M. (2016) A review of the most important medicinal plants effective
on wound healing on ethnobotany evidence of Iran. Der Pharmacia Lettre 8, 353–357. Johnstone, P. (1999) Ibn Juljul, physician and herbalist. Islamic Culture LXXIII, 37–43. Joshi, A.R. and Joshi, K. (2000) Indigenous knowledge and uses of medicinal plants by local communities
of the Kali Gandaki Watershed area, Nepal. Journal of Ethnopharmacology 73, 175–183. Jouri, M.H.and Mahdavi, M. (2010) Applied Identification of Rangeland Plants. Aeezh Press, Tehran,
p. 436. Kahle, P. (1952) Ibn Samjun’s work: “Ibn Samagun und sein Drogenbuch”. In: Documenta Islamic Ibedita.
Akademie-Verlag, Berlin. Khorasaninejad, S., Mousavi, A., Soltanloo, H., Hemmati, K. and Khalighi, A. (2010) The effect of salinity
stress on growth parameters, essential oil yield and constituent of peppermint (Mentha piperita L.).
World Applied Sciences Journal 11, 1403–1407. Lev, E. and Amar, Z. (2000) Ethnopharmacological survey of traditional drugs sold in Israel at the end of
20th century. Journal of Ethnopharmacology 72, 191–205. Levey, M. (1997) Early Arabic Pharmacology: An Introduction Based on Ancient and Medieval Sources.
E.J. Brill, Leiden, The Netherlands/Cologne, Germany. Lewin, B. (1953) The Book of Plants of Abu Hanifa al-Dinawari, edited from the unique manuscript in the
Library of the University of Istanbul, with an introduction, notes, indices, and a vocabulary of selected
words, Uppsala, Sweden/Wiesbaden, Germany. Lu, A., Jiang, M., Zhang, C. and Chan, K. (2012) An integrative approach of linking traditional Chinese medi-
cine pattern classification and biomedicine diagnosis. Journal of Ethnopharmacology 141, 549–556.
DOI: 10.1016/j.jep.2011.08.045. Ma, T., Conge, T., Zhang, H., Wang, M., Ding, W. etal. (2010) Bridging the gap between traditional Chinese
medicine and systems biology: the connection of Cold Syndrome and NEI network. Molecular BioSystems
6, 613–619. DOI: 10.1039/b914024g. Mah Van, E. (2002) A Dictionary of Iranian Plants, Soroush Press, Tehran.
fiqı. Govt. Press, Cairo.
Relationships 165
Downloaded from https://cabidigitallibrary.org by Ivanov Ivan, on 11/04/24.
Subject to the CABI Digital Library Terms & Conditions, available at https://cabidigitallibrary.org/terms-and-conditions
https://t.me/med1917
Meyer, E.H.F. (1854) Geschichte der Botanik, Vol. 3. Verlag der Gebrüder Bornträger, Königsberg,
Germany.
Mosaddegh, M. and Naghibi, F. (2002) Iran’s Traditional Medicine, Past and Present.Traditional Medicine
and Materia Medica, Vol. 1. TMRC, Tehran, pp. 2–20.
Moeini, R. and Gorji, N. (2016) Persian medicine in the world of research. Review of articles on Iranian
traditional medicine. Iranian Journal of Medical Sciences 41(3 Suppl.), S7. Mozaffarian, V. (1996) A Dictionary of Iranian Plant Names. Farhang Moaser Press, Tehran. Naghibi, F., Mosaddegh, M., Motamed, M.M. and Ghorbani, A. (2010) Labiatae family in folk medicine in
Iran: from ethnobotany to pharmacology. Iranian Journal of Pharmaceutical Sciences 4(2), 63–79 DOI:
10.22037/IJPR.2010.619.
Naghizadeh, A., Hamzeheian, D., Akbari, S., Mohammadi, F., Otoufat, T. etal. (2020) UNaProd: a universal
natural product database for materia medica of Iranian traditional medicine. Evidence-Based Comple-
mentary and Alternative Medicine 13, 3690781. DOI: 10.1155/2020/3690781. Najafi, S., Sadeghi, N.B., Deokule, S.S. and Estakhr J. (2010) Phytochemical screening of Bidaria khan-
dalense (Sant.) Jagtap & N. P. Singh Loranthus capitellatus Wall., Viscum articulatum Burm.f. and Vitex
negundo Linn. Research Journal of Pharmaceutical, Biological and Chemical Sciences 1(3), 388–393.
Najmabadi, M. (2001) History of Medicine in Ancient Iran, 2nd edn. Tehran University Press, Tehran
(in Persian). Naseri, M. and Ardakani, M.S. (2004) The School of Traditional Iranian Medicine. The definition, origin and
advantages. Iranian Journal of Pharmaceutical Sciences 3(Suppl. 2), 17–21. Nasr, S.H. (2003) Science and Civilisation, 2nd edn. The Islamic Texts Society, Cambridge. Nejad Ebrahimi, S., Hadian, J., Mirjalili, M.H., Sonboli, A. and Yousefzadi, M. (2008) Essential oil compos-
ition and antibacterial activity of Thymus caramanicus at different phenological stages. Food Chemistry
110, 927–931. Nezhadali, A. and Zarrabi Shirvan, B. (2010) Separation, identification and determination of volatile com-
pounds of Ziziphora persica Bunge using HS-SPME/GC-MS. International Journal of Environmental
Science and Development 1, 115–118. Nikbakht, A. and Kafi, M. (2008) The history of traditional medicine and herbal plants in Iran. Acta Horticul-
turae 790, 255–258. Nikbakht, A., Kafi, M. and Haghighi, M. (2008) The abilities and potentials of medicinal plants production
and herbal medicine in Iran. Acta Horticulturae 790, 259–262. Noorhosseini, N.S.A., Ashoori, L.D., Allahyar M.S. and Doozandeh, M.P. (2011) Socio-economic factors for
adoption of medicinal plants cultivation in Eshkevarat region, north of Iran. Journal of Medicinal Plants
Research 5, 30–38. Park, H.M., Lee, J.H., Yaoyao, J., Jun, H.J. and Lee, S.J. (2011) Limonene, a natural cyclic terpene, is an
agonistic ligand for adenosine A(2A) receptors. Biochemical and Biophysical Research Communica-
tions 404, 345–348. Parsaei, P., Bahmani, M., Naghdi, N., Asadi-Samani, M., Rafieian-Kopaei, M. etal. (2016) Identification of
medicinal plants effective on common cold: an ethnobotanical study of Shiraz, South Iran. Der Pharmacia
Lettre 8, 90–97. Rezadoost, H., Karimi, M. and Jafari, M. (2016) Proteomics of hot–wet and cold–dry temperaments pro-
posed in Iranian traditional medicine: a network-based study. Scientific Reports 6, 30133. DOI: 10.1038/
srep30133. Rezaeizadeh, H., Alizadeh, M., Naseri, M. and Ardakani, S. (2009) The traditional Iranian medicine point of
view on health and disease. Iranian Journal of Public Health 38(Suppl. 1), 169–172. Riha, O. (2017) Mittelalterliche Heilkunst. Das Arzneibuch Ortolfs von Baierland (um 1300). Deutscher
Wissenschafts-Verlag, Baden-Baden, Germany. Robineau, L. and Soejarto, D.D. (1996) TRAMIL: a research project on the medicinal plant resources of the
Caribbean, In: Balick, M.J., Elisabetsky, E. and Laird, S.A. (eds) Medicinal Resources of the Tropical
Forest. Columbia University Press, New York, pp. 317–325. Rouhi-Boroujeni, H., Asadi-Samani, M. and Moradi, M.T. (2016a) A review of the medicinal plants effective
on headache based on the ethnobotanical documents of Iran. Der Pharmacia Lettre 8, 37–42. Rouhi-Boroujeni, H., Mosharraf, S., Gharipour, M., Asadi-Samani, M. and Rouhi-Boroujeni, H. (2016b)
Anti-hyperlipidemic effects of sumac (Rhus coriaria L.): can sumac strengthen anti-hyperlipidemic effect
of statins? Der Pharmacia Lettre 8, 143–147. Samso, J., Rashed, R. and Vernet, J. (1996) Development of Arabic science in Andalusia. In: Rashed, R.
(ed.) Encyclopaedia of Arabic Science, Vol. 1. Routledge, London/New York, pp. 243–275.