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Epidural Steroid Injection, Thoracic Spine
KEY FACTS
TERMINOLOGY
• Injection of glucocorticoid/long-acting anesthetic into thoracic epidural space via interlaminar or transforaminal approach
PROCEDURE
• Interlaminar epidural steroid injection (ESI) ○ Define margins of lamina and interlaminar space
Image-Guided Procedures
• Transforaminal ESI ○ Ensure good visualization of neural foramen on true
lateral view
• Benefit of CT ○ Improved visualization of osseous structures in severely
osteopenic patients
○ Improved visualization of pleura/medial chest cavity
POST PROCEDURE
• Expectation
(Left) Graphic shows the spinal cord ﬈ and the relationship of vascular structures ﬇ to exiting nerve roots st. Interlaminar epidural steroid injection (ESI) approach is at the junction of the lamina and spinous process ſt. (Right) Axial graphic demonstrates relationship of nerve roots ﬈ and nerve root sleeve ſt to neural foramen. Optimal needle tip placement for transforaminal ﬇ or interlaminar ﬊ ESI is shown.
○ Improvement in pain, or cessation of pain, following
injection
• Things to do ○ Establish clinical follow-up, and have patient maintain
pain diary
○ Remind patient to expect full benefit of injection over
next 24-48 hours
OUTCOMES
• Most feared complications ○ Intraarterial injection: Spinal cord ischemia ○ Spinal cord puncture/hematoma ○ Compressive epidural hematoma ○ Pneumothorax
Normal Anatomy Normal Anatomy
450
Frontal Oblique Epidurogram Lateral Epidurogram
(Left) Oblique fluoroscopic
spot radiograph shows the needle tip in the interlaminar space ſt with contrast tracking cephalad in the thoracic epidural space ﬈. Note the superior margin of the lamina ﬊ and spinous process ﬇. (Right) A lateral fluoroscopic spot radiograph shows the needle tip positioned within the thoracic epidural space ſt. Contrast ﬈ is seen tracking cephalad within the epidural space with an amorphous appearance characteristic of epidural injections. Note the vertebral compression fracture ﬊.
Epidural Steroid Injection, Thoracic Spine
TERMINOLOGY
Abbreviations
• Thoracic epidural steroid injection
Definitions
• Injection of corticosteroid/long-acting anesthetic into thoracic epidural space via interlaminar or transforaminal approach
PREPROCEDURE
Indications
• Thoracic radiculopathy at > 1 level
• Persistent pain following vertebroplasty/kyphoplasty
Contraindications
• Coagulopathy
• Local or systemic infection
• Allergy to injectate
Getting Started
• Things to check ○ Clinical indication
– Correlation between pain and level chosen for
injection
○ Diagnostic imaging
– Adequate epidural fat/space for needle placement
○ Laboratory
– Coagulopathy – Infection
○ Informed consent
• Medications ○ Glucocorticoid ○ Long- and short-acting anesthetic ○ Myelography-safe iodinated contrast for fluoroscopy-
guided injection
PROCEDURE
Patient Position/Location
• Best procedure approach ○ Prone
– Pillow placement beneath patient (kyphosis) may
improve visualization of interlaminar space
– Interlaminar: Define margins of lamina and
interlaminar space
– Transforaminal: Ensure good visualization of neural
foramen on true lateral view; triangulate trajectory between frontal and lateral views keeping medial to avoid lung
○ Benefit of CT
– Improved visualization of osseous structures in
severely osteopenic patients
– Improved visualization of pleura/medial chest cavity
Procedure Steps
• Procedure "time out": Verify correct patient, procedure, and side
• Perform sterile prep and drape, local anesthetic
Interlaminar ○ Carefully assess trajectory intermittently while advancing
needle tip to level of superior lamina
○ Very slowly advance needle under intermittent imaging
until loss of resistance is noted on plunging glass syringe
○ Once loss of resistance occurs, attach contrast tubing
and inject contrast to confirm needle tip placement in epidural space
○ Attach injectate syringe, and inject slowly
Transforaminal ○ Carefully assess trajectory needed on biplane
fluoroscopy or CT to reach superomedial neural foramen
○ Slowly advance 22-gauge spinal needle under
intermittent imaging guidance – Placing gentle curve 20-30° in distal needle often
facilitates placement within neural foramen
○ When approaching foramen, warn patient of possible
sudden pain in case needle contacts exiting nerve
○ When needle lies within medial neural foramen, remove
stylette, and attach air-free contrast extension tubing
○ Slowly inject contrast to confirm tracking into epidural
space ○ Obtain image to document needle tip placement ○ Attach injectate syringe, and slowly inject
Alternative Procedures/Therapies
• Radiologic ○ Selective nerve root block
• Surgical ○ Decompression
POST PROCEDURE
Expected Outcome
• Improvement in or cessation of pain following injection
Things to Do
• Help patient to sitting posture
• Establish clinical follow-up, and have patient maintain pain diary
• Remind patient to expect full benefit of injection over next 24-48 hours
OUTCOMES
Problems
• Failure of pain relief
Complications
• Most feared complication(s) ○ Intraarterial injection: Spinal cord ischemia ○ Spinal cord puncture/hematoma ○ Pneumothorax
• Other complications ○ Bleeding, infection, nerve injury
SELECTED REFERENCES
1. Georgy BA: Interventional techniques in managing persistent pain after
vertebral augmentation procedures: a retrospective evaluation. Pain Physician. 10(5):673-6, 2007
2. Botwin KP et al: Adverse effects of fluoroscopically guided interlaminar
thoracic epidural steroid injections. Am J Phys Med Rehabil. 85(1):14-23, 2006
Image-Guided Procedures
451
Medial Branch Block, Lumbar Spine
KEY FACTS
TERMINOLOGY
• Selective anesthesia of lumbar nerve medial branch in diagnostic evaluation of lumbar facet joint pain
PREPROCEDURE
• Facet joint pain ○ Useful in selecting patients for medial branch
radiofrequency ablation procedure
Image-Guided Procedures
PROCEDURE
• Target: Junction of superior articular process and transverse process ○ Medial branch is numbered along with exiting lumbar
nerve root
○ L5 medial branch innervates inferior L4/5 and superior
L5/S1 facet joint
• Patient positioning ○ Prone: Angulate C-arm such that "eye" of "Scotty dog" is
well visualized
Dorsal Ramus Medial Branch Needle Placement: Lateral View
(Left) Sagittal graphic shows
the dorsal ramus medial branch ſt in the osseous groove at the junction of the superior articular process st and transverse process ﬇, immediately above the pedicle. (Right) Lateral fluoroscopy shows an L3 needle ﬈ that is superficially located. Lateral fluoroscopy is useful during needle placement to ensure that bone is reached at an appropriate depth. Single-plane imaging is deceptive, and care must be taken to ensure safe needle depth.
POST PROCEDURE
• Expectation ○ Significant reduction in facet joint pain ○ < 100% pain relief decreases likelihood of successful
rhizotomy – Injection of superior and inferior rami essential to
effectively block nervous supply to facet joint
OUTCOMES
• Failure of pain relief ○ Incorrect level or poor needle placement ○ Facet joint may not be source of pain
• Complications ○ Intravascular injection: Spinal cord ischemia ○ Dural puncture: Cauda equina injury, meningitis
452
Needle Placement: AP View Needle Position: AP View
(Left) Oblique fluoroscopic
spot radiograph shows successful needle placement for L2, 3, and 5 medial branch blocks ſt. Medial L4 needle tip is not optimal ﬇. (Right) Anteroposterior fluoroscopic spot radiograph shows the needle tips ſt at the expected location of the right L2, L3, L4, and L5 medial branches. Note that the target point of L5 dorsal ramus is at the lateral junction of the S1 superior articular process and sacral ala. Compare with previous oblique view.
Medial Branch Block, Lumbar Spine
TERMINOLOGY
Definitions
• Selective anesthesia of lumbar nerve medial branch in diagnostic evaluation of lumbar facet joint pain
PREPROCEDURE
Indications
• Chronic lower back pain
• Facet joint pain ○ Useful in selecting patients for medial branch
radiofrequency ablation (RFA) procedure
Contraindications
• Allergy to injectate
• Coagulopathy
• Local or systemic infection
• Relative contraindication ○ Pregnancy
Getting Started
• Medications ○ ± corticosteroid ○ Long-acting anesthetic ○ Short-acting anesthetic ○ Iodinated contrast (myelography-safe) is optional
PROCEDURE
Patient Position/Location
• Best procedure approach ○ Prone
– Pillow or bumper beneath patient may be useful for
stable positioning/patient comfort
– Angulate C-arm such that "eye" of "Scotty dog" is well
visualized
○ Target
– Junction of superior articular process (SAP) and
transverse process
– Medial branch is numbered along with exiting lumbar
nerve root □ L5 medial branch innervates inferior L4/5 and
superior L5/S1 facet joint
Procedure Steps
• Procedure "time out" ○ Correct patient, procedure, side, and levels of
intervention
• Optimize C-arm angulation, 10-15° toward side of injection
• Perform sterile prep and drape
• Provide local anesthetic
• Insert 22-gauge spinal needle into subcutaneous tissue
• Advance needle under intermittent fluoroscopy ○ T12/L1-L4/L5
– Target junction of SAP and transverse process (small
osseous groove)
○ L5 dorsal ramus
– Target junction of S1 SAP and sacral ala
• When bone is reached, turn bevel down (away from neural foramen) ○ Gently aspirate to confirm extravascular
Image-Guided Procedures
• Inject small amount of contrast ○ If desired to confirm needle tip placement/extravascular
injection
• Place needles at additional levels as indicated
• Attach injectate syringe, and inject slowly ○ Assess pain with each injection
Findings and Reporting
• Level(s) injected
• Pain scale and character before and after injection(s)
Alternative Procedures/Therapies
• Radiologic ○ Lumbar facet joint block ○ Lumbar epidural steroid injection
• Other ○ Neurolysis
– RFA – Cryoablation
POST PROCEDURE
Expected Outcome
• Significant reduction in pain corresponding to facet joint injected ○ < 100% pain relief decreases likelihood of successful
rhizotomy – Injection of superior and inferior rami essential to
effectively block nervous supply to facet joint
OUTCOMES
Problems
• Failure of pain relief ○ Incorrect level or poor needle placement ○ Facet joint may not be source of pain
Complications
• Most feared complication(s) ○ Intravascular injection
– Spinal cord ischemia
○ Dural puncture
– Spinal cord or cauda equina injury – Meningitis
• Other complications ○ Bleeding ○ Infection ○ Nerve root injury
SELECTED REFERENCES
1. Chou R et al: Nonsurgical interventional therapies for low back pain: a review
of the evidence for an American Pain Society clinical practice guideline. Spine (Phila Pa 1976). 34(10):1078-93, 2009
2. Lee CJ et al: Intravascular injection in lumbar medial branch block: a
prospective evaluation of 1433 injections. Anesth Analg. 106(4):1274-8, table of contents, 2008
3. Manchikanti L et al: Lumbar facet joint nerve blocks in managing chronic
facet joint pain: one-year follow-up of a randomized, double-blind controlled trial: Clinical Trial NCT00355914. Pain Physician. 11(2):121-32, 2008
4. Verrills P et al: The incidence of intravascular penetration in medial branch
blocks: cervical, thoracic, and lumbar spines. Spine (Phila Pa 1976). 33(6):E174-7, 2008
453
Facet Joint Injection, Lumbar Spine
KEY FACTS
TERMINOLOGY
• Injection of corticosteroid and anesthetic into lumbar facet joint
PREPROCEDURE
• Facet joint osteoarthritis
• Synovial cyst causing neurologic symptoms
PROCEDURE
Image-Guided Procedures
• Prone
• Angle C-arm or PA fluoroscopy tube slightly toward side of joint to be injected ○ Generally, lower 1/3 of joint is most amenable to needle
entry/injection in arthritic joint
• Ensure proper level
• Slowly inject only enough contrast to confirm that needle tip is in joint space
• Note pain scale and pain characteristics ○ Before, during, and after injection
(Left) Axial NECT shows the needle tip ſt at the superolateral margin of the right L4/5 facet joint. Note that the needle is nearly within the plane of the image and that the needle tip casts a dark artifact ﬇. (Right) Oblique fluoroscopic radiograph shows a 22-gauge spinal needle passing between adjacent articular facets st into the right L4/5 facet joint ſt. Correlation with lateral imaging is helpful in determining depth. A "pop" is felt upon penetration of the joint capsule.
• Synovial cyst therapeutic rupture ○ May require significant injection pressure ○ See sudden spread of contrast into epidural space
OUTCOMES
• Failure to alleviate pain ○ Wrong level injected ○ Injection extraarticular ○ Facet joint not source of pain ○ May require multilevel injections
• Most feared complications ○ Thecal sac puncture, cord injury, meningitis
• Other complications ○ Nerve root injury, bleeding, infection
CT Facet Injection Needle Positioning: Frontal Oblique View
454
(Left) Fluoroscopic spot radiograph obtained during lumbar facet joint injection shows contrast ﬇ about the joint; particularly note linear craniocaudal extension of contrast ſt, which is characteristic of an intraarticular injection. (Right) AP fluoroscopic spot radiograph shows contrast opacification within the facet joint extending caudally into a focal collection consistent with a synovial cyst ſt.
Mixed Intra-/Extraarticular Injection: AP
Oblique View
Contrast Injection: Facet Joint and
Synovial Cyst
Facet Joint Injection, Lumbar Spine
TERMINOLOGY
Abbreviations
• Facet joint injection (FJI)
Definitions
• Injection of corticosteroid ± anesthetic into lumbar facet joint
PREPROCEDURE
Indications
• Facet joint osteoarthritis
• Synovial cyst causing neurologic symptoms
Contraindications
• Local or systemic infection
• Coagulopathy
• Allergy to injectate
Getting Started
• Things to check ○ Imaging of facet joint for pathology and anatomic
relationships ○ Informed consent ○ Laboratory: Coagulation parameters
PROCEDURE
Patient Position/Location
• Best procedure approach ○ Prone
– Angle C-arm or PA fluoroscopy tube slightly toward
side of joint to be injected
– May need slight cranial angulation as well to optimize
joint visualization
– Generally, lower 1/3 of joint is most amenable to
needle entry/injection in arthritic joint □ Inferior recess may be only accessible site for
injection in severely arthritic joint
Procedure Steps
• Ensure correct spine level for injection
• Target lower 1/3 of joint space ○ Often, arthritic joints will have redundancy inferiorly,
creating more accessible joint space
• Perform sterile prep and drape
• Apply local anesthetic
• Place spinal needle into subcutaneous tissue, and confirm trajectory with imaging
• Advance until bone is reached or feel needle advance into joint space
• If reach bone, "walk" needle into joint
• Attach preloaded contrast tubing and syringe
• Slowly inject only enough contrast to confirm needle tip in joint space
• Remix and attach injectate syringe
• Slowly inject
• Note patient's symptoms during and immediately following injection
Synovial cyst therapeutic rupture ○ Same steps as FJI
Image-Guided Procedures
○ Alternate approach is interlaminar puncture of cyst
– CT guidance suggested for translaminar approach
○ Patient will often feel "pop" with cyst rupture
– May require significant injection pressure – Can be quite painful for patient
○ Interventionalist will see sudden spread of contrast into
epidural space with cyst rupture
Alternative Procedures/Therapies
• Radiologic ○ Medial branch block ○ Epidural steroid injection ○ Percutaneous facet joint fusion
POST PROCEDURE
Expected Outcome
• Improved pain symptoms
Things to Do
• Help patient from procedure table
• Establish follow-up
• Remind patient to keep pain diary until next clinic appointment
Things to Avoid
• Strenuous activity for remainder of day
• Bathing for 48 hours
OUTCOMES
Problems
• Failure to alleviate pain ○ Technical failure
– Wrong level injected – Injection extraarticular
○ Clinical failure
– Facet joint not source of pain
□ May require multilevel injections
– Multifactorial pain
Complications
• Most feared complication(s) ○ Thecal sac puncture
– Cord injury – Meningitis – Cerebrospinal fluid leak
• Other complications ○ Bleeding ○ Infection ○ Nerve injury
SELECTED REFERENCES
1. Datta S et al: Systematic assessment of diagnostic accuracy and therapeutic
utility of lumbar facet joint interventions. Pain Physician. 12(2):437-60, 2009
2. Martha JF et al: Outcome of percutaneous rupture of lumbar synovial cysts:
a case series of 101 patients. Spine J. 9(11):899-904, 2009
455
Selective Nerve Root Block, Lumbar Spine
KEY FACTS
TERMINOLOGY
• Selective corticosteroid and long-acting anesthetic injection of lumbar nerve root at level of neural foramen
PREPROCEDURE
• Imaging ○ Single or multilevel involvement
PROCEDURE
Image-Guided Procedures
• Carefully determine correct level(s) for injection ○ Nerve root exits below pedicle of same numbered
vertebral body
• 2 approaches for lumbar selective nerve root block ○ Angle C-arm toward side to be injected and target
beneath pedicle/"eye" of "Scotty dog"
○ Using AP projection, mark skin 6-8 cm lateral to neural
foramen and determine trajectory to foramen
• Assess pain score/reproduction of pain before, during, and after injection
(Left) Sagittal T1-weighted MR shows hyperintense fat st in the neural foramina surrounding the lumbar nerve roots. The nerve root is located superiorly ſt, like thoracic nerves. Cervical nerves are located inferiorly. (Right) AP spot radiograph shows the needle tip ﬇ deep within the neural foramen beneath the central aspect of the pedicle ſt with contrast within the left L5 neural foramen ﬈ as well as a large volume of contrast extending into the right dorsolateral epidural space from the L4-S1 levels st.
• Findings and reporting ○ Pain before, during, and after injection ○ Was pain reproduced by procedure? ○ Level(s) injected including injectate volume and
medications injected
POST PROCEDURE
• Expectation ○ Significant reduction in pain following injection (may take
48-72 hours)
OUTCOMES
• Most feared complications ○ Dural puncture (spinal cord injury, meningitis, CSF leak) ○ Vascular injury/intravascular injection (spinal cord
ischemia)
• Problems ○ Failure of pain relief ○ Vasovagal reaction
Anatomy Intraforaminal and Epidural Injection
456
Needle Placement: Oblique View Intraforaminal and Epidural Injection
(Left) Oblique "Scotty dog"
view of the lumbar spine allows targeting of the neural foramen beneath the pedicle/"eye" ſt, and then advance the needle parallel to the imaging beam ﬇. Intermittent lateral imaging is essential to determine needle depth. (Right) AP image from another patient shows the expected linear appearance of contrast tracking along the exiting lumbar nerve root ſt. In addition, there is contrast extending slightly above the neural foramen, medial to the pedicle, into the epidural space ﬇.
Selective Nerve Root Block, Lumbar Spine
TERMINOLOGY
Abbreviations
• Selective nerve root block (SNRB), epidural steroid injection (ESI)
Definitions
• Selective corticosteroid and long-acting anesthetic injection of lumbar nerve root at level of neural foramen
PREPROCEDURE
Indications
• Lumbar radiculopathy ○ Lumbar osteoarthritis ○ Posttraumatic osteoarthritis
Contraindications
• Coagulopathy
• Local or systemic infection
• Severe allergy to components of injectate
• Relative ○ Pregnancy, iodinated contrast allergy, recent live virus
vaccination
Getting Started
• Things to check ○ Preprocedure imaging
– Look for causative lesion and single or multilevel
involvement
○ Laboratory data
– Signs of infection or coagulopathy
○ Informed consent
• Medications ○ Corticosteroid ○ Long-acting anesthetic ○ Short-acting (local) anesthetic ○ Myelography-safe iodinated contrast
PROCEDURE
Patient Position/Location
• Best procedure approach ○ Prone
– 2 approaches for lumbar SNRB
□ Angle C-arm toward side to be injected and target
foramen beneath pedicle/"eye" of "Scotty dog"
□ Use anteroposterior projection and mark skin 6-8
cm lateral to neural foramen
Procedure Steps
• Procedural "time out" ○ Verify correct patient, side of injection, and procedure to
be performed
• Carefully determine correct level(s) for injection
• Mark skin at appropriate level and perform sterile prep and drape
• Anchor 22-gauge spinal needle and check trajectory with AP and lateral fluoroscopy
• Carefully advance needle under intermittent frontal and lateral fluoroscopy until foramen or bone is reached
Image-Guided Procedures
• Remove stylette, observe hub for blood, then attach contrast syringe/tubing
• Aspirate gently, then inject myelography-safe contrast ○ Watch for vascular enhancement and adjust needle tip if
necessary
○ Should see contrast track along nerve root
• Remove contrast tubing then mix and attach injectate syringe
• Slowly inject, noting patient pain and whether characteristic pain is reproduced
• Remove needle and obtain hemostasis
Findings and Reporting
• Pain before, during, and after injection ○ Was pain reproduced by procedure?
• Level(s) injected including injectate volume and medications injected ○ SNRB ± transforaminal ESI
POST PROCEDURE
Expected Outcome
• Significant reduction in pain following injection ○ May experience worsening of pain between local
anesthetic wearing off and corticosteroid taking effect (48-72 hours)
Things to Do
• Remind patient to keep pain diary until next clinic visit
Things to Avoid
• Bathing for 48-72 hours
OUTCOMES
Problems
• Failure of pain relief ○ Improper needle placement/extraforaminal injection ○ Improper level injected
• Vasovagal reaction
Complications
• Most feared complication(s) ○ Dural puncture (spinal cord injury, meningitis, CSF leak) ○ Vascular injury/intravascular injection (spinal cord
ischemia)
• Other complications ○ Bleeding, nerve root injury, infection
SELECTED REFERENCES
1. Boezaart AP et al: Paravertebral block: cervical, thoracic, lumbar, and sacral.
Curr Opin Anaesthesiol. 22(5):637-43, 2009
2. Eckel TS et al: Epidural steroid injections and selective nerve root blocks.
Tech Vasc Interv Radiol. 12(1):11-21, 2009
3. Manchikanti L et al: Comprehensive review of neurophysiologic basis and
diagnostic interventions in managing chronic spinal pain. Pain Physician. 12(4):E71-120, 2009
4. Roberts ST et al: Efficacy of lumbosacral transforaminal epidural steroid
injections: a systematic review. PM R. 1(7):657-68, 2009
457
Epidural Steroid Injection, Lumbar Spine
KEY FACTS
TERMINOLOGY
• Corticosteroid/anesthetic injection into lumbar epidural space via interlaminar, transforaminal, or caudal approach
PREPROCEDURE
• Indications ○ Lumbar radiculopathy ○ Residual pain following vertebroplasty/kyphoplasty
Image-Guided Procedures
• Things to check ○ Prior imaging: Adequate epidural space (especially
important in postoperative back!)
• Avoid interlaminar approach in patient with severe canal stenosis without identifiable epidural space on preprocedure imaging
• Literature supports use of nonparticulate steroid (dexamethasone) to minimize possibility of small vessel vascular embolization
Severe Central Canal Stenosis Needle Placement: Interlaminar ESI
(Left) Sagittal T1WI MR shows
severe central canal stenosis ſt at each disc level due to disc bulge/osteophyte and posterior ligamentous laxity. Note the epidural fat ﬇ at levels above surgery. (Right) AP fluoroscopic image obtained during lumbar epidural steroid injection (ESI) shows anatomic landmarks and well-defined interlaminar space ﬇. Note the spinous process st and cortex of laminae above and below ſt.
PROCEDURE
• Interlaminar epidural steroid injection (ESI) ○ Target superior lamina near midline
• Transforaminal ESI ○ Target superomedial neural foramen
• Caudal ESI ○ Target sacral hiatus at midline, and consider catheter
placement in patients requiring higher lumbar level injections
POST PROCEDURE
• Expectations ○ Reproduction of pain with needle placement/injection ○ Significant improvement in pain after injection
OUTCOMES
• Most feared complications ○ Intravascular injection/spinal cord ischemia ○ Spinal cord puncture
458
Transforaminal ESI Contrast Spread in Dorsal Epidural Space
(Left) AP view obtained in this
patient undergoing right L1/2 transforaminal ESI shows contrast ſt spreading medial to the pedicle and cephalad within the lumbar epidural space. (Right) The lateral view provides additional confirmation that contrast is predominantly spreading within the dorsal epidural space ﬈ and is noted to extend readily in a cephalad direction.
Epidural Steroid Injection, Lumbar Spine
TERMINOLOGY
Abbreviations
• Epidural steroid injection (ESI)
Definitions
• Corticosteroid/anesthetic injection into lumbar epidural space via interlaminar or transforaminal approach
PREPROCEDURE
Indications
• Lumbar radiculopathy ○ Degenerative disc disease ○ Posttraumatic
Contraindications
• Coagulopathy
• Allergy to injectate
• Local or systemic infection
• Relative contraindications ○ Iodinated contrast allergy, pregnancy, active hepatitis
Getting Started
• Things to check ○ Laboratory data
– Coagulation studies as indicated for patients
undergoing anticoagulation therapy □ Prothrombin time, activated partial thromboplastin
time, international normalized ratio, platelet count
• Equipment list ○ Interlaminar ESI
– Glass syringe with preservative-free saline ("loss of
resistance" technique)
– 18- to 22-gauge Tuohy or Whitacre needle
○ Transforaminal ESI
– 22-gauge spinal needle
○ Caudal ESI
– 18- to 22-gauge Tuohy or Whitacre needle
PROCEDURE
Patient Position/Location
• Best procedure approach ○ Prone
Procedure Steps
• Steroid: Literature supports use of nonparticulate steroid (dexamethasone) to minimize possibility of small vessel vascular embolization ○ No strong literature support for better efficacy of
particulate or Depo preparations
Interlaminar ○ Target superior lamina near midline ○ Carefully "walk" off lamina superiorly, then attach glass
syringe
○ Very carefully advance needle until loss of resistance
occurs with glass syringe plunging
Transforaminal ○ Target superomedial neural foramen ○ Slowly advance adjacent to exiting nerve root
Caudal
Image-Guided Procedures
○ Sacral hiatus/canal ○ Advance Tuohy needle through canal to epidural space
using "loss of resistance" technique – If contrast does not opacify high enough into lumbar
canal, consider use of catheter or vascular sheath □ Exchange needle over 0.035 wire, and navigate
sheath or catheter over wire to desired level under fluoroscopic guidance
• Document needle placement with imaging
• Attach injectate, and slowly inject
Findings and Reporting
• Document level, amount of pain before and after procedure
POST PROCEDURE
Expected Outcome
• Reproduction of pain with needle placement/injection
• Improvement in pain after injection
Things to Avoid
• Interlaminar approach in patient with severe canal stenosis without identifiable epidural space on preprocedure imaging
OUTCOMES
Problems
• Incorrect level injected/failure of pain relief
• Vasovagal reaction
Complications
• Most feared complication(s) ○ Intravascular injection
– Spinal cord ischemia
○ Spinal cord puncture
SELECTED REFERENCES
1. Dietrich TJ et al: Particulate versus non-particulate steroids for lumbar
transforaminal or interlaminar epidural steroid injections: an update. Skeletal Radiol. 44(2):149-55, 2015
2. Fekete T et al: The effect of epidural steroid injection on postoperative
outcome in patients from the lumbar spinal stenosis outcome study. Spine (Phila Pa 1976). 40(16):1303-10, 2015
3. Rathmell JP et al: Safeguards to prevent neurologic complications after
epidural steroid injections: consensus opinions from a multidisciplinary working group and national organizations. Anesthesiology. 122(5):974-84, 2015
4. El-Yahchouchi C et al: The noninferiority of the nonparticulate steroid
dexamethasone vs the particulate steroids betamethasone and triamcinolone in lumbar transforaminal epidural steroid injections. Pain Med. 14(11):1650-7, 2013
5. Chang Chien GC et al: Digital subtraction angiography does not reliably
prevent paraplegia associated with lumbar transforaminal epidural steroid injection. Pain Physician. 15(6):515-23, 2012
6. Peterson C et al: Evidence-based radiology (part 1): is there sufficient
research to support the use of therapeutic injections for the spine and sacroiliac joints? Skeletal Radiol. 39(1):5-9, 2010
7. Wybier M et al: Paraplegia complicating selective steroid injections of the
lumbar spine. Report of five cases and review of the literature. Eur Radiol. 20(1):181-9, 2010
8. Eckel TS et al: Epidural steroid injections and selective nerve root blocks.
Tech Vasc Interv Radiol. 12(1):11-21, 2009
459