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Jerey J. Schwartz, MD
Associate Professor Department of Anesthesiology Yale University School of Medicine New Haven, CT
Kinza Sentissi, MD
Resident Department of Anesthesiology Brigham and Women’s Hospital Boston, MA
Shahzad Shae, MD
Instructor in Anaesthesia Department of Anesthesia, Critical Care and Pain Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston, MA
Aali Shah, MD
Assistant Professor of Clinical Anesthesia Indiana University School of Medicine Indianapolis, IN
Deepak Sharma, MBBS, MD, DM
Departments of Anesthesiology & Pain Medicine and Neurological Surgery University of Washington Seattle, WA
Andrew Shaw, MB, FRCA, FFICM, FCCM
Professor and Executive Vice Chair Department of Anesthesiology Vanderbilt University School of Medicine Nashville, TN
Kara Siegrist, MD
Anesthesiology Resident Vanderbilt University Medical Center Nashville, TN
Bantayehu Sileshi, MD
Department of Anesthesiology Vanderbilt University Medical Center Nashville, TN
Julia Sobol, MD
Assistant Professor of Anesthesiology Columbia University Medical Center NewYork- Presbyterian Hospital New York, NY
Alissa Sodickson, MD
Sta Anesthesiologist Department of Anesthesiology, Perioperative and Pain Medicine Brigham and Women’s Hospital Boston, MA
Andrew F. Stasic, MD
Associate Professor of Clinical Anesthesia Indiana University School of Medicine Indianapolis, IN
Jing Tao, MD
Assistant Professor Department of Anesthesiology Yale University School of Medicine New Haven, CT
Paloma Toledo, MD, MPH
Center for Healthcare Studies Northwestern University, Feinberg School of Medicine Chicago, IL
Muoi Trinh, MD, MPH
Assistant Professor of Anesthesiology Department of Anesthesiology Icahn School of Medicine at Mount Sinai New York, NY
Agnieszka Trzcinka, MD
Instructor of Anesthesia Department of Anesthesiology, Perioperative and Pain Medicine Brigham and Women’s Hospital Harvard Medical School Boston, MA
Gebhard Wagener, MD
Associate Professor Department of Anesthesiology Columbia University College of Physicians and Surgeons New York, NY
XX CONTRIBUTORS
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Cynthia Wang, MD
Assistant Professor Department of Anesthesiology and Pain Management University of Texas Southwestern Medical Center Dallas, TX
Scott C. Watkins, MD
Assistant Professor of Anesthesiology Department of Anesthesiology Division of Pediatric Anesthesia Vanderbilt University Medical Center Nashville, TN
Sheena M. Weaver, MD
Assistant Professor of Clinical Anesthesiology Department of Anesthesiology Division of Critical Care Medicine Vanderbilt University Medical Center Nashville, TN
Christopher Allen- John Webb, MD
Clinical Instructor of Anesthesiology Regional Anesthesiology Fellow Department of Anesthesiology, Perioperative, and Pain Medicine Stanford University Stanford, CA
Paul David Weyker, MD
Critical Care Fellow Department of Anesthesia and Perioperative Care University of California, San Francisco San Francisco, CA
Peggy White, MD
Assistant Professor of Anesthesiology Department of Anesthesiology University of Florida Gainesville, FL
Cristina Wood, MD, MS
Assistant Professor Department of Anesthesiology University of Colorado School of Medicine Aurora, CO
Stephanie Yacoubian, MD
Sta Anesthesiologist Department of Anesthesiology, Perioperative and Pain Medicine Brigham and Women’s Hospital Boston, MA
Natacha Zamor, MD
Sta Anesthesiologist Signature Healthcare Brockton, MA
Jamie M. Zorn, MD
Obstetric Anesthesiology Fellow Department of Anesthesiology University of Pittsburgh School of Medicine Magee- Womens Hospital of the University of Pittsburgh Medical Center Pittsburgh, PA
CONTRIBUTORS XXI
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ADVANCED PERIOPERATIVE CRISIS
MANAGEMENT
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1
PART I.
CRISIS RESOURCE MANAGEMENT
NONTECHNICAL SKILLS OF TEAM PERFORMANCE
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1.
A CRITICAL THINKING APPROACH TO THE UNSTABLE PATIENT
Mark E. Nunnally, Arna Banerjee, and Matthew D. McEvoy
INTRODUCTION
deliberately practice managing these situations, and reect on their performance.11 Although emphasis is placed on
Several factors unfairly shape the medical community’s approach to crisis. First, almost all assertions about ade­quacy of care are inuenced by hindsight bias.
1,2
Second, there is a common misperception that choices are obvious in real time, and that there are simple routes to success and failure.3 Such factors underscore the truth that clinicians do
not think enough about how to think about crises.
Cardiac arrest under anesthesia is rare, and outcomes are better in the perioperative arena than in other settings, particularly out of hospital arrest. Modern estimates of inci­dence range from 5.64 to 7.1 per 10,000.5 Encountering a rare event interrupts routine care and can lead to errors in patient care and result in injury to the patients or sen­tinel events.6 With such a low frequency, it becomes challenging to maintain competence in these areas, and practitioners must master skills in crisis management inde­pendent of direct practice. is chapter focuses on two such approaches. e rst is learning to recognize deterioration early enough to reverse it and avoid arrest. e second is practicing simulated crises.
Recognizing crisis and taking evasive action are di­cult skills. e rareness of cardiac arrest is confounded by the multiple sources of failure, further rarefying infrequent events. However, the practice of anesthesiology deals with rare complications routinely. Dicult mask ventilation combined with dicult laryngoscopy might occur at a fre­quency of 4 in 1000,7 while malignant hyperthermia occurs in about 0.18 in100,000.8 In order to be prepared for res­cue, low- frequency events need to be regarded as routine.
medical knowledge and learning technical skills, critical incident reporting and observational studies show that nontechnical skills such as dynamic decision- making and teamwork are a major determinant of success in crisis man­agement.12 To manage a crisis a clinician must rst detect the problem and then take necessary steps to correct it. is involves a constant loop of observation and recognition of the crisis, dynamic decision- making, and therapeutic action followed by reevaluation.
Strategies used in Cockpit/ Crew Resource Management (CRM) have been adopted by the healthcare industry to aid in this process and promote safety. ese include the use of checklists and cognitive aids, established protocols for cri­sis management, and formal training in dynamic decision­making, resource management, and teamwork. Studies have shown that acquisition of these skills requires specic education.13 Simulation- based curricula have been devel­oped to integrate these strategies and teach these skills.
16
Teamwork training programs have also been developed,
14-
of which TeamSTEPPS, Veterans Aairs Medical team training program, and CRM are a few. e Eective Management of Anesthetic Crises course is a standard­ized 2.5- day simulation- based course and is a component of training for Fellowship of Australian and New Zealand College of Anesthetists.
17
ere is growing knowledge that to successfully manage a crisis a clinician requires both technical and nontechnical skills. Nontechnical skills complement technical skills and contribute to safe and ecient task performance. ey do not relate to medical knowledge and can be broadly divided
IS THIS A PROBLEM?
into two categories— cognitive skills (resource utilization, planning, decision- making, situation awareness) and inter­personal skills (team work, leadership, communication).18
Even the astute and experienced clinician can make errors during crisis situations,9 as shown by closed claims analy­sis and simulated studies.10 To attain expertise, clinicians need to be exposed to these rare challenging situations,
Simulation- based curricula have been developed and used eectively to teach and practice these skills.
19
Human factors literature shows that cognitive functions can fail during stress. Cognitive aids (posters, owcharts,
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checklists, mnemonics) can aid clinicians during crisis situ­ations and help them recall key actions.20 Simulated train­ing sessions may be helpful in educating clinicians on the use and implementation of these aids.21 Mnemonics and protocols have also been developed to aid specically dur­ing crisis.
22
But, does this training translate into clinical practice? Studies have shown that rst- year residents perform better than third- year residents aer simulation- based education in critical care medicine.23 In a review of a small number of studies using simulation- based learning, authors found that CRM skills learned in the simulation center are transferred to the clinical setting and this improves clini­cal outcome and may even show a decrease in mortality.24 Simulation- trained residents also responded to cardiac arrest events with greater compliance to American Heart Association protocols than more experienced team leaders not trained with simulation.25 More studies are required to see whether simulation- based CRM training improves patient outcome.
quite right may be the best way for experts to see an arrest before it happens— this likely means that there is a deep level of pattern recognition/ perturbation to which one should pay attention in routine processes of care, always asking why a patient may be deviating from responding to ongoing management as expected.
When crisis, or pending crisis, is recognized, clinicians must act quickly and decisively. Creating and narrowing a dierential diagnosis and formulating a stepwise approach to management lets a clinician take decisive action in the short space of time before arrest occurs. A classic strat­egy, promoted by Lawrence D. H. Wood, involves asking three crucial questions of the patient’s circulation.28 e rst question asks whether the cardiac output is too high or too low. is question splits the dierential diagnoses into high- and low- cardiac output shock states. e second asks whether the heart is too full or too empty. Intravenous uid resuscitation is frequently a solution to intraopera­tive shock, but there are times when resuscitation might be harmful. e nal question addresses “what doesn’t t?” Rarely is crisis the result of a single random event. Shock
PRINCIPLES FOR DEVELOPING A CRITICAL THINKING APPROACH
can unmask other problems. An astute clinician should always be thinking of concomitant problems or alternative explanations.
Crisis rarely occurs out of the blue, but it seems that way in real time. e evolution of arrest is oen presaged by subtle abnormalities. Although these abnormalities take time to evolve, oen they are not clinically apparent until shortly before crisis, and they do not cross a detectable threshold until late in their evolution.26 Combinations of more subtle signs may be apparent earlier, but detection of these requires expertise and is confounded by xation bias,27 when there is a natural tendency to focus on one feature to the exclusion of others. is is one reason why someone new to a crisis situation may see things those involved in the process over time will not.
How does a clinician best recognize and treat insta­bility? Traditionally this emphasizes vital signs, which oer reasonable sensitivity but poor specicity until cri­sis is imminent. A systolic blood pressure of 95 mmHg in an adult could be benign or a marker of pending arrest. Another approach is to look at markers of perfusion as a way to assess the adequacy of the circulation. Urine out­put, serum lactate, assessment of tissue oxygenation, as with near- infrared spectroscopy (NIRS) or other tissue- specic probes, or central or mixed- venous hemoglobin oxygen saturations are indirect variables for the assessment of the circulation. Finally, understanding that experts may uncon­sciously recognize patterns, any sense that something is not
SOME PRACTICAL STEPS
As noted above, persistent vigilance and practice are two key components to being prepared when a perioperative crisis occurs. A mental model that may help when such an event does occur should, as noted above, start with circula­tion. While there are a number of major categories in which emergencies can occur (as denoted in the sections of this book), the nal common pathway for all crises involves the circulatory system. As such, starting with an evaluation of hemodynamics and then moving to other systems is logi­cal, particularly for the novice, but also for the expert— any of whom can be prone to mental errors under stress. us, when a patient becomes unstable, we suggest that clinicians as the following questions:
1. Is there a pulse? [If no, start CPR and follow appropriate ACLS management guidelines, with noted alterations based on specic diagnosis (e.g., LAST)]
2. Is the origin of the instability:
a. Pump— need for inotropic support?
b. Pipes— need for increased/ reduced aerload?
4 PART I. CRISIS RESOURCE MANAGEMENT
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c. Preload— need for additional preload/ volume?
d. Voltage— arrhythmia causing disturbance?
e. Vessels— coronary ischemia/ infarction?
f. Valves— severe valvular disease causing problem?
3. If answers to all of the above are “no,” then the issue is not directly of cardiac origin and the clinician can move to sequentially assessing other organ systems:
a. Pulmonary— oxygenation, ventilation, mechanics,
airway control?
b. Neurologic— global or focal issue? peripheral or
central?
c. Metabolic/ Endocrine— past medical history? recent
lab values?
d. Toxins— medication administration history, and so
forth.
4. Keep in mind that cardiac instability is always the nal common pathway and that this sequence should be iteratively pursued until a denitive diagnosis is reached, the problem averted, and the patient is stabilized.
As you approach subsequent chapters in this text, we encourage continued use of this paradigm to consider how to place each specic diagnosis and treatment within one’s overall mental model for approaching the unstable patient.
REFERENCES
1. Caplan RA, Posner KL, Cheney FW. Eect of outcome
on physician judgments of appropriateness of care. JAMA. 1991;265(15):1957– 60.
2. Einav S, Kaufman N, Sela HY. Maternal cardiac arrest and perimor-
tem caesarean delivery: evidence or expert- based? Resuscitation. 2012;83(10):1191– 1200.
3. Wears RL, Cook RI. e illusion of explanation. Acad. Emerg. Med.
2004;11(10):1064– 5.
4. Nunnally ME, O’Connor MF, Kordylewski H, Westlake B, Dutton
RP. e incidence and risk factors for perioperative cardiac arrest observed in the national anesthesia clinical outcomes registry. Anesth. Analg. 2015;120(2):364– 70.
5. Kazaure HS, Roman SA, Rosenthal RA, Sosa JA. Cardiac arrest
among surgical patients: an analysis of incidence, patient charac­teristics, and outcomes in ACS- NSQIP. JAMA Surgery. 2013; 148(1):14– 21.
6. Joint Commission on Accreditation of Healthcare Organizations.
Sentinel event statistics— June 30, 2005. http:// www.jcaho.org/ accredited+organizations/ sentinel/ sentinel+event+statistics. htm2005. Accessed May 5, 2006.
7. Kheterpal S, Healy D, Aziz MF, et al. Incidence, predictors, and
outcome of dicult mask ventilation combined with dicult
laryngoscopy : a report from the Multicenter Perioperative Outcomes Group. Journal of the American Society of Anesthesiologists. 2013;119(6):1360– 9.
8. Lu Z, Rosenberg H, Brady JE, Li G. Prevalence of malignant hyper­thermia diagnosis in New York State ambulatory surgery center dis­charge records 2002 to 2011. Anesth. Analg. 2016;122(2):449– 53.
9. Metzner J, Posner KL, Lam MS, Domino KB. Closed claims’ analysis. Best Practice and Research Clinical Anaesthesiology. 2011;25(2):263– 76.
10. DeAnda A, Gaba D. Role of experience in the response to simulated critical incidents. Anesth. Analg. 1991;72(3):308– 15.
11. Ericsson KA. Deliberate practice and the acquisition and main­tenance of expert performance in medicine and related domains. Acad. Med. 2004;79(10):S70– S81.
12. Gaba DM, Fish KJ, Howard SK, Burden A. Crisis Management in Anesthesiology. 2nd ed. Philadelphia, PA: Elsevier Saunders; 2014.
13. Blackwood J, Du JP, Nettel- Aguirre A, Djogovic D, Joynt C. Does teaching crisis resource management skills improve resuscita­tion performance in pediatric residents? Pediatr. Crit. Care Med. 2014;15(4):e168– e174.
14. Holzman RS, Cooper JB, Gaba DM, Philip JH, Small SD, Feinstein D. Anesthesia crisis resource management: real- life simulation train­ing in operating room crises. J. Clin. Anesth. 1995;7(8):675– 87.
15. Gaba DM, DeAnda A. A comprehensive anesthesia simulation envi­ronment: re- creating the operating room for research and training. Anesthesiology. 1988;69(3):387– 94.
16. Gaba DM, Howard SK, Fish KJ, Smith BE, Sowb YA. Simulation­based training in anesthesia crisis resource management (ACRM): a decade of experience. Simulation and Gaming. 2001;32(2):175– 93.
17. Weller J, Morris R, Watterson L, et al. Eective management of anaes­thetic crises: development and evaluation of a college- accredited simulation- based course for anaesthesia education in Australia and New Zealand. Simulation in Healthcare. 2006;1(4):209– 14.
18. Flin R, Patey R, Glavin R, Maran N. Anaesthetists’ non- technical skills. Br. J. Anaesth. 2010;105(1):38– 44.
19. Yee B, Naik VN, Joo HS, et al. Nontechnical skills in anesthesia crisis management with repeated exposure to simulation- based education. Journal of the American Society of Anesthesiologists. 2005;103(2):241– 8.
20. Gaba DM. Perioperative cognitive aids in anesthesia: what, who, how, and why bother? Anesth. Analg. 2013;117(5):1033– 6.
21. Goldhaber- Fiebert SN, Howard SK. Implementing emergency man­uals: can cognitive aids help translate best practices for patient care during acute events? Anesth. Analg. 2013;117(5):1149– 61.
22. Runciman W, Merry A. Crises in clinical care: an approach to man­agement. uality and Safety in Health Care. 2005;14(3):156– 63.
23. Singer BD, Corbridge TC, Schroedl CJ, et al. First- year residents outperform third- year residents aer simulation- based education in critical care medicine. Simulation in Healthcare. 2013;8(2):67.
24. Boet S, Bould MD, Fung L, et al. Transfer of learning and patient outcome in simulated crisis resource management: a system­atic review. Canadian Journal of Anesthesia/ Journal canadien d’anesthésie. 2014;61(6):571– 82.
25. Wayne DB, Didwania A, Feinglass J, Fudala MJ, Barsuk JH, McGaghie WC. Simulation- based education improves quality of care during cardiac arrest team responses at an academic teaching hospital: a case- control study. Chest. 2008;133(1):56– 61.
26. Cook R, Rasmussen J. “Going solid”: a model of system dynamics and consequences for patient safety. uality and Safety in Health Care. 2005;14(2):130– 4.
27. Jermias J. Cognitive dissonance and resistance to change: the inu­ence of commitment conrmation and feedback on judgment usefulness of accounting systems. Accounting, Organizations and Society. 2001;26(2):141– 60.
28. Wood LDH. e pathophysiology of the circulation in critical ill­ness. In: Hall J, Schmidt G, Wood LDH, eds., Principles of Critical Care. 3rd ed. New York: McGraw Hill; 2005:231– 48.
A CRITICAL THINKING APPROACH TO THE UNSTABLE PATIENT 5
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