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10 Use of Three-Dimensional Technology for Virtual Surgical Planning in Oral…
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Data
Collection
Virtual
Surgical
Planning
Merge Data
Into BSP
Design
Prosthesis
in BSP
Refine
Prosthesis
in MM
Clinical exam,
Cone beam CT,
fibula CT
Patient specific
data
Import and align
dental model and
fibula to CBCT
Postition implants
into fibula and
add teeth via
denture design
Export fibula and
prosthetic STL
Dental models or
optical intraoral
scan
Create implant access holes and finalize prosthesis
contours
3D Print
Prosthesis
Post
Processing
Fig. 10.8 Example of Jaw in A day workow (Reproduced with permission from Williams, Fayette C et al. “Immediate Teeth in Fibulas: Planning and Digital Workow with Point-of-Care 3D Printing.” Journal of oral and maxillofacial surgery: ofcial journal of the American Association of Oral and Maxillofacial Surgeons vol. 78,8 (2020): 1320–1327. doi:10.1016/j.joms.2020.04.006)
Add model
support
Alcohol bath, cure
Add pink
composite
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References
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anorl.2020.06.011; Epub 2020 Jun 30.
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10. Palines PA, Ferrer JR, Yoo A, St Hilaire H, Stalder MW.Simplifying bony midface reconstruc­tion with patient-specic titanium plates. Plast Reconstr Surg Glob Open. 2021;9(4):e3555.
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11. Rubio-Palau J, Ayats-Soler M, Albert-Cazalla A, Martìnez-Padilla I, Prieto-Gundin A, Prieto­Peronnet N, Ramìrez-Fernández MP, Mareque-Bueno J.Accuracy of virtually planned maxil­lary distraction in cleft patients—an evaluative study. Ann Maxillofac Surg. 2021;11(1):49–57.
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PMC8407633.
12. De Virgilio A, Iocca O, Di Maio P, Malvezzi L, Pellini R, Mercante G, Spriano G. Head and neck soft tissue reconstruction with anterolateral thigh aps with various components: development of an algorithm for ap selection in different clinical scenarios. Microsurgery. 2019;39(7):590–7.
13. Liu K, Zhang W, Wang Y, Xiang DW, Shi HB, Liu QL. Fibula osteal ap with proximal peroneal perforator skin paddle for composite oromandibular reconstruction: a case report. Medicine (Baltimore). 2020;99(50):e23590.
14. Pereira N, Valenzuela D, Mangelsdorff G, Kufeke M, Roa R.Detection of perforators for free ap planning using smartphone thermal imaging: a concordance study with computed tomo­graphic angiography in 120 perforators. Plast Reconstr Surg. 2018;141(3):787–92.
15. Rajati M, Pezeshki Rad M, Irani S, Khorsandi MT, Motasaddi ZM.Accuracy of high- resolution computed tomography inlocating facial nerve injury sites in temporal bone trauma. Eur Arch Otorhinolaryngol. 2014;271(8):2185–9.
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16. Cheng K, Leinkram D, Howes D, Clark J.Incorporating ‘off-the-shelf’reconstruction plates into the digital plan for mandible reconstruction. Int J Clin Oncol Cancer Ther. 2021;1(1):1–4.
17. Garrido-Martínez P, Quispe-López N, Montesdeoca-García N, Esparza-Gómez G, Cebrián­Carretero JL.Maxillary reconstruction with subperiosteal implants in a cancer patient: a one­year follow-up. J Clin Exp Dent. 2022;14(3):e293.
18. Zhang N, Liu S, Hu Z, etal. Accuracy of virtual Sur- gical planning in two-jaw orthognathic surgery: com- parison of planned and actual results. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122(2):143–51.
19. Resnick CM, Inverso G, Wrzosek M, etal. Is there a difference in cost between standard and vir­tual surgical planning for orthognathic surgery? J Oral Maxillofac Surg. 2016;74(9):1827–33.
20. Cheng H, Chen BP, Soleas IM, etal. Prolonged oper- ative duration increases risk of surgical site infec- tions: a systematic review. Surg Infect (Larchmt). 2017;18(6):722–35.
21. Tondin GM, Leal MOCD, Costa ST, Grillo R, Jodas CRP, Teixeira RG.Evaluation of the accuracy of virtual planning in bimaxillary orthognathic surgery: systematic review. Br J Oral Maxillofac Surg. 2021;S0266-4356(21):00343. https://doi.org/10.1016/j.bjoms.2021.09.010; Epub ahead of print. PMID: 35120785.
22. Chen Z, Mo S, Fan X, You Y, Ye G, Zhou N.A meta-analysis and systematic review comparing the effectiveness of traditional and virtual surgical planning for orthognathic surgery: based on randomized clinical trials. J Oral Maxillofac Surg. 2021;79(2):471.e1–471.e19. https://doi.
org/10.1016/j.joms.2020.09.005. Epub 2020 Sep 9. PMID: 33031773.
23. Bernstein JM, Daly MJ, Chan H, Qiu J, Goldstein D, Muhanna N, de Almeida JR, Irish JC.Accuracy and reproducibility of virtual cutting guides and 3D-navigation for osteotomies of the mandible and maxilla. PloS One. 2017;12(3):e0173111.
24. Jenkins GW, Iqbal S, West N, Ellabban I, Kennedy MP, Adams JR.Dosimetry-guided virtual surgical planning in the reconstruction of mandibular osteoradionecrosis. Br J Oral Maxillofac Surg. 2021;59(8):947–51.
25. Lee IJ, Koom WS, Lee CG, Kim YB, Yoo SW, Keum KC, Kim GE, Choi EC, Cha IH.Risk fac­tors and dose–effect relationship for mandibular osteoradionecrosis in oral and oropharyngeal cancer patients. Int J Radiat Oncol Biol Phys. 2009;75(4):1084–91.
26. Gutwald R, Jaeger R, Lambers FM.Customized mandibular reconstruction plates improve mechanical performance in a mandibular reconstruction model. Comput Methods Biomech Biomed Engin. 2017;20(4):426–35.
27. Smith MH, Schrag CH, Chandarana SP, Cobb JG, Matthews TW, Mckenzie CD, Matthews JL. Novel plate design to improve mandibular and maxillary reconstruction with the Osteocutaneous bula ap. Plast Reconstr Surg Glob Open. 2019;7(1):e2094.
28. Anolik RA, Nelson JA, Rosen EB, Disa J, Matros E, Allen RJ Jr. Immediate dental implant placement in the oncologic setting: a conceptual framework. Plast Reconstr Surg Glob Open. 2021;9(9):e3671.
29. Melville JC, Manis CS, Shum JW, Alsuwied D. Single-unit 3D-printed titanium recon­struction plate for maxillary reconstruction: the evolution of surgical reconstruction for maxillary defects—a case report and review of current techniques. J Oral Maxillofac Surg. 2019;77(4):874–e1.
30. Gellrich NC, Zimmerer RM, Spalthoff S, Jehn P, Pott PC, Rana M, Rahlf B.A customised digitally engineered solution for xed dental rehabilitation in severe bone deciency: a new innovative line extension in implant dentistry. J Craniomaxillofac Surg. 2017;45(10):1632–8.
31. Spalthoff S, Borrmann M, Jehn P, Rahlf B, Gellrich NC, Korn P.Comparison of conventional and digital workow for dental rehabilitation with a novel patient-specic framework implant system: an experimental dataset evaluation. Int J Implant Dent. 2022;8(1):1–8.
32. Barry CP, MacDhabheid C, Tobin K, Stassen LF, Lennon P, Toner M, O’Regan E, Clark JR. ‘Out of house’ virtual surgical planning for mandible reconstruction after cancer resection: is it oncologically safe? Int J Oral Maxillofac Surg. 2021;50(8):999–1002.
33. Urken ML, Buchbinder D, Weinberg H, etal. Primary placement of osseointegrated implants in microvascular mandibular reconstruction. Otolaryngol Head Neck Surg. 1989;101:56.
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34. Rosen EB, Ahmed ZU, Habib AA, Huryn JM, Randazzo JD, Cracchiolo JR, Matros E, Nelson J, Allen RJ Jr. Interim implant-supported resection prosthesis following bula free ap recon­struction of the arch with immediate implants: a novel approach for the oncologic patient. Int J Periodontics Restorative Dent. 2020;40(6):861–7. https://doi.org/10.11607/prd.4675. PMID: 33151192; PMCID: PMC8383382.
35. Hutchison IL, Dawood A, Tanner S. Immediate implant supported bridgework simul­taneous with jaw reconstruction for a patient with mandibular osteosarcoma. Br Dent J. 2009;206(3):143–6. https://doi.org/10.1038/sj.bdj.2009.57. PMID: 19218947.
36. Patel A, Harrison P, Cheng A, Bray B, Bell RB.Fibular reconstruction of the maxilla and man­dible with immediate implant-supported prosthetic rehabilitation: jaw in a day. Oral Maxillofac Surg Clin North Am. 2019;31(3):369–86. https://doi.org/10.1016/j.coms.2019.03.002. Epub 2019 Jun 1. PMID: 31164268.
37. Williams FC, etal. Immediate teeth in bulas: planning and digital workow with point-of­care 3D printing. J Oral Maxillofac Surg. 2020;78(8):1320–7.
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Chapter 11
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Advancing Immediate Dental Rehabilitation inFree Tissue Transfer Utilizing Point-of-Care Digital Workows and3D Printing
DanielHammer, MarilynAndersen, JustinOdette, RaymondP.Shupak, MichaelAndersen, FayetteC.Williams, andRoderickY.Kim
Introduction
Maxillofacial reconstructive surgery poses a unique set of challenges to the surgeon. A defect in this region often results from pathology or trauma, and the resulting defect affects both form and function with potential changes to speech, nutrition, swallow function, and esthetics. Maxillofacial defects also have a signicant effect on the patients’ psychosocial well-being. Therefore, oral and dental rehabilitation is
D. Hammer (*) Department of Oral and Maxillofacial Surgery, Naval Medical Center San Diego, San Diego, CA, USA e-mail: daniel.a.hammer.mil@health.mil
M. Andersen Department of Oral and Maxillofacial Surgery, Naval Hospital Twentynine Palms, Twentynine Palms, CA, USA e-mail: marilyn.a.andersen.mil@health.mil
J. Odette Dental Department, USS Theodore Roosevelt (CVN 71), San Diego, CA, USA e-mail: justin.r.odette.mil@health.mil
R. P. Shupak Division of Oral and Maxillofacial Surgery, Geisinger Medical Center, Danville, PA, USA e-mail: rshupak@geisinger.edu
M. Andersen Department of Hospital Dentistry, Naval Medical Center San Diego, San Diego, CA, USA e-mail: michael.r.andersen.mil@health.mil
F. C. Williams · R. Y. Kim Department of Oral and Maxillofacial Surgery, John Peter Smith Hospital, Fort Worth, TX, USA e-mail: FWilliam@jpshealth.org; RKim01@jpshealth.org
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2023 J. C. Melville et al. (eds.), Advancements and Innovations in OMFS, ENT, and Facial Plastic Surgery, https://doi.org/10.1007/978-3-031-32099-6_11
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imperative to fully restore the patient and should not be ignored and completed as soon as predictably possible. Unfortunately, current data suggest that most patients undergoing jaw reconstruction following pathologic resection do not receive imme­diate implants or an immediate prosthesis at the time of initial surgery [1].
The advantages of immediate dental rehabilitation (dental implants and tempo­rary prosthesis at time of primary reconstruction) include a decrease in the number of surgeries and expedited return to form and function. These advantages can improve the patients’ psychosocial and overall well-being. Potential obstacles to immediate dental rehabilitation include the learning curve to optimally virtual plan the reconstruction, gaining familiarity with the complexities of 3D manufacturing, nancial reimbursement, and nally, collaborating with a suitable restorative pro­vider capable of delivering a nal restoration. Since comprehensive maxillofacial reconstruction incorporates dental rehabilitation, strong consideration should be given to immediate dental rehabilitation when feasible.
D. Hammer et al.
Immediate Dental Implant Placement inOsseous Free Flaps
Immediate dental implant placement into osseous free aps is well documented and has a high success rate [24]. The accuracy and success rates have further increased with the incorporation of virtual surgical planning (VSP) [5]. Some of the chal­lenges previously faced by immediate implant placement and dental prosthesis delivery can be simplied by computer-aided design and computer-aided manufac­turing (CAD/CAM) technologies [6].
The implant positions should be determined at the time of planning the osseous free ap. This allows for the fabrication of patient-specic cutting guides, which incorporate additional features allowing for guided implant placement. Properly positioned implants are imperative for dental rehabilitation, especially in the imme­diate setting. This minor shift in protocol greatly increases the likelihood of provid­ing a sound foundation for delivery of an immediate prosthesis. With the use of this protocol, the authors have maintained a high implant success rate in reconstructing defects resultant to both benign and malignant disease and trauma. With the advent and application of CAD/CAM technologies, immediate dental rehabilitation has become predictable and safe.
History of Immediate Dental Rehabilitation inOsseous Free Flaps
Immediate dental rehabilitation with microvascular free tissue reconstruction was rst completed by Dr. Iain Hutchison and Dr. Andrew Dawood in 2007 to recon­struct a mandibular continuity defect secondary to ballistic trauma. Previously,
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dental rehabilitation in free tissue transfer was completed in a staged manner either by using prelaminated aps 6weeks after dental implant placement or by placing the dental implants in the osseous free ap transorally after initial healing. Dr. Hutchinson and Dr. Dawood’s surgery involved placement of dental implants into a scapula with an immediate provisional prosthesis being delivered before leaving the operating room [7, 8]. Since its inception, immediate dental rehabilitation in free tissue transfer has gained popularity and predictability and has extended its applica­tion to a wide variety of clinical situations [913].
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Expanded Applications ofImmediate Dental Rehabilitation in Free Tissue Transfer
Initially, immediate dental rehabilitation was only recommended for secondary trauma reconstruction or reconstruction of defects secondary to benign disease. It was believed that these reconstructions in the setting of malignancy would lead to increased complication rate, especially when the patient required adjuvant radiation treatment. In the authors’ experience, postoperative radiation has not been associ­ated with decreased rates of implant integration, further supported by emerging lit­erature [1013]. When implants are placed immediately during bula reconstruction, adjuvant radiation therapy does not begin for another 4–6weeks. After radiation begins, there are several more weeks before radiation doses reach signicant bio­logic levels. Since most of the implant integration is complete before the higher doses of radiation accumulate, the integration rate of implants in bulas prior to radiation is higher than implants placed after radiation [14, 15].
Furthermore, it is commonly believed that the reconstruction of a composite defect with an osteocutaneous ap is a contraindication to immediate dental reha­bilitation with concerns of an inability to achieve a watertight closure and possible decreased skin paddle survival. Our experience has shown that skin paddles can be successfully used with immediate rehabilitation when designed properly. In fact, to perform a successful vestibular reconstruction, the skin paddle is integral. When implants are placed at the suture line between the skin paddle and native mucosa, a near watertight closure can be obtained. This results in a more favorable soft tissue interface leading to less tissue mobility, resulting in improved implant health com­pared to native non-keratinized oral mucosa. The major disadvantage of utilizing a skin paddle is the potential need for secondary debulking procedures.
Until recently, one of the major challenges to immediate dental rehabilitation of a patient with a malignancy was the prolonged time needed to design and fabricate the temporary dental prosthesis, which could be 6 or more weeks. It was simply not acceptable to delay extirpation of the patient’s tumor to offer immediate dental reha­bilitation. By leveraging emerging technologies, the temporary dental prosthesis can now be fabricated and ready for delivery within 24h of the planning the free ap reconstruction. This timeline is possible by utilizing open-source design
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software and in-house 3D printing (additive resin printing) or polymethylmethacry­late (PMMA) milling. Both technologies have revolutionized the ability to provide a patient-customized rehabilitation within the time constraints of treating malignant tumors [16].
Advantages of using 3D printing (additive resin printing) include rapid manufac­turing time and low cost of equipment and consumable resins. The advantages of milled pre-polymerized PMMA, such as polychromatic esthetics, exural strength, and resistance to the accumulation of biolms, far surpass those of current 3D-printed resins. However, PMMA mills are more costly compared to resin printers.
The in-house digital workow used to create the prosthesis provides a high­quality prosthesis in signicantly less time and at less cost than using commercially available dental labs [17].
D. Hammer et al.
Preoperative Digital Workow: Data Gathering toTemporary Prosthesis Design
The immediate dental rehabilitation digital workow can be performed in any ofce or clinic setting with the appropriate hardware and software. Preoperative imaging includes a maxillofacial CT or cone beam CT (CBCT) and CT angiography of the bilateral lower extremities for evaluation of vessel presence and patency and implant planning. The lower extremity imaging must have a slice thickness of 1mm or less, and only patient-specic data should be used for virtual surgical planning (VSP). It is important that in the maxillofacial CT or CBCT is obtained with the teeth slightly apart in open occlusion to allow more accurate merging of the preoperative denti­tion with the CT data. Intraoral scans or stone models can be sent to an appropriate surgical VSP engineer according to the preference of the surgeon.
During the VSP session, the resection and the bony reconstruction are planned as dictated by the pathology and defect, followed by virtual placement of implants. Virtual implant and abutment STL les are brought into the planning environment and adjusted according to standard implant principles. We prefer to have implants emerging from the anterior surface of the bula as it will position the skin paddle in an orientation to reconstruct the vestibule. However, in cases where this is not pos­sible, implants can also emerge from the posterior surface of the bula to allow for appropriate ap geometry. The implant guide is digitally built with the bula oste­otomy guide. It is important to note that the drill offset should be built into the guide based on the fully guided implant system that is used (Figs.11.1 and 11.2).
When planning dental implant placement within the bula, there should be approximately 15–18mm of restorative space from the platform of the implant to the opposing occlusal surface. In our experience, the implants themselves should be no less than 7mm apart from each other (external edge to external edge of adjacent platform) to ensure cleansability of the prosthesis and at least 3mm from bular
Simulated Postoperative Anatomy
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Fig. 11.1 Finalized VSP of an immediate mandibular reconstruction. Note the restorative space (15–18mm) needed for prosthesis restoration. Here the bula segments are shown at the inferior border; however, the bula should be placed to allow for proper implant emergence. This often positions the bula above the level of the inferior boarder
Reconstruction
VSP
Fibula Guide Detail - Dental Implants
Virtual Surgical Planning
Dental Implant cylinders measure 3.8 mm x 13 mm.
Each dental implant shelf is 5 mm thick and is offset 7 mm from the top of the implant. Total distance from top of implant shelf to botom of implant is 25 mm.
All measurements are approximate.
12 mm
25 mm
Fig. 11.2 Fibula cut guide with merged guided implant sleeves. Note the implant guide sleeve offset that corresponds to the offset on the guided implant drill length
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osteotomies to maintain the integrity of the bony junction. Implant depths should be planned for the platforms to be 1–2mm subcrestal due to expected crestal bone loss.
Following the VSP session, STL les of the bula reconstruction with implants are requested from the engineer. This ensures that the shells are accurately overlaid (bula/implant/existing teeth) in the 3D work environment. This step is critical to ensure that the planning session and implant positioning will align with the in-house fabricated prosthesis. Then the digital in-house workow is followed, as previously described [15]. The patient’s STL les are then imported to the 3D printer software for temporary prosthesis fabrication.
For partial arch dental rehabilitation in a patient with existing dentition in the region that will be removed, the temporary prosthesis design is cloned from the patient’s existing dentition. The STL data is recorded from the intraoral scan and modied within the software. A base is created with the close model feature. This creates an identical copy of the patient’s dentition. After this step, a tooth-borne guide is created digitally on teeth within the non-resected portion of the patient’s contralateral dental arch. These two constructs are then combined with an interpo­sitional connector. The prosthesis is further digitally smoothed and the digital implant abutments are subtracted from the prosthesis using a Boolean difference function to create holes in the prosthesis for intraoperative abutment pickup (Figs. 11.3, 11.4, 11.5, and 11.6). The prosthesis is then manufactured through either 3D resin printing or PMMA milling throughputs. In patients with no previous existing dentition in the area being reconstructed, the dentition can be planned using denture software using the same workow discussed above.
Fig. 11.3 Creating a tooth-borne oating prosthesis for partial dental arch reconstruction. This portion of the guide will connect to the prosthesis and register to a printed model for pickup in the leg
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