
- •30. Pathophysiology of digestion.
- •30.1. What is deficiency of digestion?
- •30.2. How is deficiency of digestion is classified?
- •30.3. What factors can cause digestion deficiency?
- •30.4. What principles do they use in experimental modulating of digestion deficiency?
- •30.5. With what influences into nervous system do they modulate indigestion?
- •30.6. What disorders of humoral regulation do they use for modeling of indigestion?
- •30.7. What syndromes characterize digestion deficiency?
- •30.8. With what symptoms is dyspeptical syndrome manifestated?
- •30.9. What is anorexia? When does it appear?
- •30.10. What is heartburn? What is its mechanism?
- •30.11. What is belch? What are its mechanisms?
- •30.12. What is nausea and vomiting? What are its mechanisms?
- •30.13. What is constipation? When does it happen?
- •30.14. What is altered bowel sounds? When does it arise?
- •30.15. What is diarrhea? By what can it be caused?
- •30.16. What can be reason of dehydration of organism?
- •30.17. What disorders of pH condition are symptoms of disorders of digestion?
- •30.18. What causes intestinal autointoxication in case of disorder of digestion?
- •30.19. What mechanisms can cause pain syndrome in case of injuries of digestive system?
- •30.20. What disorders of motorical, secretory and absorption function of digestive system can cause disorders of digestion?
- •30.21. What reasons can cause disorders of chewing? What inportance for digestion have these disorders?
- •30.22. What is caries of teeth?
- •30.23. How pathogenesis of caries is nowadays understood?
- •30.24. What is periodontitis? What factors can cause it?
- •30.25. What are the reasons and importance of hypersalivation?
- •30.26. What are the reasons of and importance of hyposalivation?
- •30.27. What is dysphagy? name its reasons and influence.
- •30.28. What is gastric dyskinesia? What are its variants?
- •30.28. Name reasons and importance of hyperkynetic dyskinesia of stomach.
- •30.30. What is pylorospasm?
- •30.31. Name reasons and importance of hypotonic dyskinesia of stomach
- •30.32. There are some types of pathologic gastric secretion:
- •30.33. How is gastric hypersecretion manifestated? What is its importance?
- •30.34. How can gastric hypersecretion be modelated in experiment?
- •30.35. What is ulcer disease? What is its etiology?
- •30.36. What are theories of pathogenesis of ulcer disease?
- •30.37. What pathogenic variants of gastric ulcer do they distinguish nowadays?
- •30.38. What is exogenous gastric ulcer? What can be its reason?
- •30.39. What is peptic ulcer? How is it modelated in experiment?
- •30.40. What is trophic ulcers of stomach? How is it reproduced in experiment?
- •30.41. What is hyporegeneratory ulcers of stomach? What can cause it?
- •30.42. What is the manifestation of gastric hyposecretion? What is its importance?
- •30.43. How can gastric hyposecretion be modelated in experiment?
- •30.44. What are the reasons of pancreatic hypersecretion? How it can manifestate?
- •30.45. What is acute pancreatitis? What is its etiology?
- •30.46. What is main link of pathogenesis of acute pancreatitis? What pathogenic variants of this disease do they distinguish?
- •30.47. What is the characteristic for primary alterative variant of development of acute pancreatitis?
- •30.48. What can cause development of hypertensive variant of acute pancreatitis?
- •30.49. What conditions cause refluxe variant of pancreatitis?
- •30.50. Describe pathogenesis of local changes in case of acute pancreatitis.
- •30.51. What mechanisms can cause pancreatic shock?
- •30.52. With what symptoms is pancreatic shock manifestated?
- •30.53. What reasons can cause development of pancreatic hyposecretion? What is its importance?
- •30.54. What is maldigestion syndrome? What symptoms is its manifestation?
- •30.55. What is intestinal dyskinesia? What are its variants?
- •30.57. How are hypokynetical diskynesies of intestines manfestated? What is its importance?
- •30.58. What is intestinal impassability? How is it classified?
- •30.59. Which changes in organism are the manifestation of intestinal impassability? What is its pathogenesis?
- •30.60. What reasons can cause disorders of defecation? How does such disorders manifestate?
- •30.61. What is malabsorption syndrome? What reasons can cause the disorders of absorption?
- •30.62. What reasons can cause the disorders of absorption in intestines?
- •30.63. What is intestinal enzymopathy? How can it be manifestate?
- •30.64. What enterocytic disorders can cause malabsorption syndrome?
- •30.65. What postenterocytic disorders can cause disorders of absorption of substances in intestines?
30.26. What are the reasons of and importance of hyposalivation?
Reasons of hyposalivation are :
central braking of secretion of salivary glands (fear, pain);
influence of m-holinolytics - drugs, that block m-holinoreceptors of peripherial tissues;
injury of secretory cells of salivary glands (inflammation, tumors);
disorders of secretion (purchase of ducts of salivary glands by concrements);
dehydration of the organism.
Consequences of hyposalivation are:
Disorders of chewing, formation of food lump, gulping, that causes disorders of next stages of digestion;
traumatization of mucous layer of mouth with next development of its inflammation (stomatitis);
active development of microorganisms caused by decreasing of bactericide of influence of saliva (few lisocime) and formation of rub, from desquamated epithelium on surface of tongue (good nutrient for microorganisms);
disorders of trophicinfluence of salive, that further development of caries.
30.27. What is dysphagy? name its reasons and influence.
Dysphagy is disorder of complex reflective act of gulping that takes place in 3 phases: oral (arbitary), pharyngeal (fast involuntary), esophageal (slow involuntary)
Reasons of dysphagy can be:
injury of receptors of mucous membrane of oral cavity (stomatitis) and pharynx (angine)
injure of neural centers in cortex of brain (disorder of deliberate phase of gulping) and center of gulping in the region of IV ventricle
injure of sensitive afferent and motorical efferent nerves that take part in gulp reflexes
injury of muscles of tongue, pharynx and esophagus. Disorders of muscles of esophagus can be manifestated as spastical conditions (idiopathical difuse spasm, achalasy of cardia: hypotonical, atonical) that are characterized as disorders of esophageal peristaltics.
malform and acquired defects of palate
mechanical obstacles (tumors, obstacles, obstruction of esophagus)
In case of dysphagy it is hard to eat, it causes starvation and exhausion, saliva and parts of food can go to respiratory ways and cause aspiration pneumonia and gangrene of lungs
30.28. What is gastric dyskinesia? What are its variants?
Gastric dyskinesia is disorders of motoric function of stomach. They distinguish 2 variants of dyskinesia: hypertonic and hypotonic.
Hypertonic variant is characterized by increasing of tonus of non-striated muscles of stomach(hypertony) and increasing of its peristaltics (hyperkynesy).
Hypotonic variant is characterized by hypotony and hypokynesy.
30.28. Name reasons and importance of hyperkynetic dyskinesia of stomach.
Reasons of disorders of stomach of hyperkynetic type can be:
some food factors (rough food, alcohole);
increasing of stomach secretion;
increasing of tonus of nervus vagus;
some intestinal hormones for example motiline.
Hypertonic and hyperkinesia cause:
long delay of contents in stomach, that further increasing of gasric secretion and development of ulcers on mucous layer;
development of antiperistaltics of stomach that causes such symptoms as dyspepsy, belch, nausea, vomiting.