2. In patients with sickle cell disease, acute painful crises are precipitated by:

   1. high altitude

   2. pregnancy

   3. dehydration

   4. systemic infection

   5. All of the above

3. Characteristic features of acute leukemia include:

   1. rapid onset of fever and anemia

   2. mouth ulceration and gingival hypertrophy

   3. myalgia arthralgia and skin rashes

   4. normocytic or macrocytic anemia, with primitive white cells

   5. All of the above

4. General manifestations of anemia include;

   1. bradycardia

   2. small pulse pressure

   3. dyspnea on effort

   4. high grade fever

   5. clubbing of fingers

5. Thrombocytopenia is caused by one of the following drugs:

   1. coumadin

   2. heparin

   3. aspirin

   4. penicillin

   5. cephalexin

6. The hazards of blood transfusion include:

   1. urticaria

   2. congestive cardiac failure

   3. fever

   4. acute intravascular hemolysis

   5. all of the above

1. Causes of leg ulcers include:

   1. diabetes mellitus

   2. leprosy

   3. sickle-cell disease

   4. syphilis

   5. all of the above

2. The following suggest that a pigmented skin lesion is a malignant melanoma:

   1. asymmetry

   2. irregular border and elevation

   3. irregular colour

   4. diameter more than 0.5 cm

   5. all of the above

3. Recognized causes of erythema multiforme include:

   1. herpes simplex infection

   2. mycoplasma pneumonia

   3. pregnancy

   4. systemic lupus erythematosus

   5. all of the above

8