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Lecture 13 - Pregnancy and child birth.pdf
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Pregnancy

Lecture 13

The endocrine glands and pregnancy

hCG

First secreted by trophoblast cells before implantation and secreted later by the placenta

hCG – binds to LH receptors on the luteal cells, preventing degeneration of the corpus luteum

Thus maintains estrogen and progesterone

This increased estrogen stimulates the secretion of prostagandins from the endometruim of the uterus, which then increases vascular permeability and swelling of the endometruim

Why is hCG so important?

What happens when progesterone levels fall

Corpus luteum degererates

Necrosis of the endometrium

Menstruation

All prevented by secretion of hCG by the blastocyst

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