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ECHO 2013 / Constriction or Cardiomyopathy Paradoxical Diastolic Heart Failure

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Normal vs Abnormal Heart

Relaxation and Suction

Normal > 10 cm/s

Medial 13 cm/s

Medial 3 cm/s

©2011 MFMER |

slide-61 ©2012 MFMER | 3225607-61

Constriction

Abnormal Septal Motion

Consider Constriction if a patient with CHF has normal EF and abnormal septal motion

©2012 MFMER

©2011 MFMER |

slide-62 | 3225607-62

Hepatic Vein Diastolic Flow Reversal

Myocardial vs Pericardial

Myocardial

Pericardial

Inspirational

Expiratory

reversal

reversal

©2011 MFMER |

slide-63 ©2012 MFMER | 3225607-63

Summary History to Diagnosis

Symptoms Anatomy

Clinician

Cath

Patient

CT

 

 

MRI

 

Echo

Function

Pressures

Echo

Cath

Nuclear

MRI

CT

©2012 MFMER | 3225607-64

Hepatic vein Doppler

©2011 MFMER |

slide-65 ©2012 MFMER | 3225607-65

Restriction vs Constriction

Similar Hemodynamics

RCM

Constriction

Equalization of Diastolic Pressures

Dip and Plateau / Square Root

©2012 MFMER | 3225607-66

Myocardial Relaxation

Decreased in All Myocardial Diseases

Early diastolic mitral annulus velocity (e’)

is Non-invasive tau

slide-67

 

©2011

 

CP1254003MFMER-8 |

 

©2012 MFMER | 3225607-67

Echo Diagnostic Criteria for Constriction Sensitivity and Specificity

Variable

Sensitivity

Specificity

Positive

Negative

 

(%)

(%)

PV(%)

PV(%)

 

 

 

 

 

Septal shift vs. no septal shift

92

69

92

71

Percent change in mitral E

84

73

92

55

velocity >= 14.6%

 

 

 

 

Medial e’ velocity >= 9 cm/s

83

81

94

57

Medial e’/Lateral e’ >= 0.91

75

85

95

50

HV diastolic reversal/velocity

76

88

96

49

in expiration >= 0.79

 

 

 

 

 

 

 

 

 

IVC max diameter > 2.1 cm

79

28

80

27

and % change < 50%

 

 

 

 

Terrence Welch et al. Accepted to ACC 2013

©2012 MFMER | 3225607-68

Case #3

A 71 year old man presents with progressively worsening of dyspnea. Referred for pericardiectomy. Physical examination demonstrated marked elevation of JVP and S3. Echocardiography, CT, and hemodynamic cardiac catheterization provided following data.

©2012 MFMER | 3225607-69

Constrictive Pericarditis in the Modern Era

Novel Criteria for Diagnosis in the Cardiac Cath Laboratory (Talreja, Nishimura, Oh, Holmes. Jan. 2008 JACC)

Discordant change

Constriction

Restriction(RMC)

Concordant change