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ECHO 2013 / Cardiac Magnetic Resonance Imaging in the Adult Congenital Patient

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Magnetic Resonance Angiography

Cine Angiography

CMR in Adult CHD

Program Description

CMR Technique

Reproducibility

Other Strengths and Limitations

Cases

MRI as the Gold Standard

Global LV and RV volume measurements with a 3D approach that has no geometric assumptions

Ex vivo validation with phantoms and casts

In vivo validation with normal hearts, x-ray contrast ventriculograms

Both stroke volumes and flow measurements

LV and RV mass compared to autopsy and animal hearts

QUESTION

The reproducibility of volume measurements by cardiac MR is as good for the RV as for the LV.

1.True

2.False

CMR LV Interstudy Reproducibility

Grothues Am J Cardiol 2002

20 normals, 20 HF, 20 LVH underwent 2 CMRs and 2 2D echocardiograms

CMR LV Interstudy Reproducibility

Grothues Am J Cardiol 2002

Coefficient of Variability calculated as the SD of the differences divided by the mean of the parameter under consideration

Coefficient of Variability

 

CMR

2DE

LV EDV

2.9% to 4.9%

5.5% to 10.5%

LV ESV *

4.4% to 9.2%

13.7% to 20.3%

LV EF *

2.4% to 7.3%

8.6% to 19.4%

LV Mass *

2.8% to 4.8%

11.6% to 15.7%

CMR RV Interstudy Reproducibility

Grothues Am Heart J 2004

Same 60 subjects, age 51 + 18 yrs

Coefficient of Variability

 

CMR

RV EDV

4.2% to 7.8%

RV ESV

8.1% to 18.1%

RV EF

4.3% to 10.4%

RV Mass

7.8% to 9.4%

Correlation values lower for RV parameters (0.77- 0.98) than LV parameters (0.94-0.99)

CMR Reproducibility of RV

Measurements

Mooij J Magn Reson Imaging 2008

CMR 4-Chamber SSFP