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13. Com
p
lications of Assisted Re
p
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3
b
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d
cancer ris
k
s. W
h
i
l
e current stu
d
ies on t
h
e
s
a
f
et
y
o
f
assiste
d
repro
d
uction are
g
enera
lly
reassurin
g
, t
h
e stu
dy
by
Hansen
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l
. [23] reportin
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a
h
i
gh
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k
o
f
b
irt
h
d
e
f
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f
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l
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ll
a
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In
d
ex
A
bd
omina
l
wa
ll
laparoscopic sur
g
er
y
and perforation of,
29
t
rocar
,
hernia at site of
,
25
Abdominal wound closure
,
43–49
f
ai
l
ure o
f
, 43–44
m
anagement o
f
, 48–4
9
m
ana
g
ement o
f
l
ate, 49
f
ascia c
l
osure an
d
, 46–4
7
superfi
cial
,
47
hernia
,
incisional and
,
44–45
i
ncisions for
,
4
5
peritoneum closure and, 45–4
6
r
isk factors, 44–4
5
s
kin closure and, 4
8
superfi
cia
l
b
rea
kd
own o
f
, 49
s
urgica
l
consi
d
erations
f
or, 4
5
ACC/AHA. Se
e
American Co
ll
e
g
e o
f
C
ar
d
io
l
o
gy
/American Heart
Association
Ade
p
t, adhesion
p
revention with, 57–59,
58f
Adhesiolysis, 34
Adhesion
(
s
)
f
ormation, 52, 10
3
hy
steroscopic sur
g
er
y
an
d
f
ormation o
f
,
1
03
i
ntraa
bd
omina
l
, past sur
g
ica
l
h
istor
y
an
d
,
6
8
,
69
t
Adhesion
p
revention
A
de
p
t for, 57–59, 58f
adjuvants, 5
2
crystalloid for, 52–5
3
Interceed for, 58–59, 58
f
Interge
l
f
or, 53–59, 58
f
r
ecent a
d
vances in, 52–59
AFS.
S
ee American Ferti
l
it
y
Societ
y
A
lb
umin, 12
9
American Colle
g
e of Cardiolo
gy
/American
H
eart Association (ACC/AHA), 87,
8
7t
American Fertility Society (AFS), 5
4
American Society of Anesthesiologists
cat
i
on, 86, 86
t
Anaero
b
ic t
h
res
h
o
ld
(AT), 8
8
Anastomotic
l
ea
k
, 15
Anesthesia
complications related to, laparoscop
y
a
nd
,
25–2
6
high-risk patient and intraoperative, 91
laparoscopy, complications related to,
25
–2
6
r
a
d
ica
l
sur
g
er
y
comp
l
ications an
d
,
2–1
3
r
is
k
re
d
uction re
l
atin
g
to, 12–1
3
Anti
b
iotic
s
i
nfection followin
g
gy
necolo
g
ical sur
g
er
y
a
nd choice of
,
5
,
6
t
prophylactic, 8
h
ysterectomy, 9
T
OP, 8–
9
ASA classifi
catio
n
.
S
ee American Society o
f
Anesthesiologists classifi
catio
n
Assiste
d
re
p
ro
d
uction
com
p
lications, 127–13
3
o
varian stimulation and
,
127–13
0
embryo transfer technique complications
a
nd
,
131–13
2
s
afety, 132
s
urgical procedures, complications
a
ssociate
d
wit
h
, 130–131
AT
.
Se
e
An
ae
r
ob
i
c
th
r
eshold
B
Bacterial va
g
inosis (BV), 3
antibiotics for
,
5
i
nfectious morbidit
y
, post-h
y
sterectom
y
a
nd
,
4–
5
vaginal cuff cellulitis, post-hysterectom
y
a
n
d
, 4–
5
Benzy
l
penici
ll
in, 13
Bipo
l
ar e
l
ectrosur
g
ica
l
d
evice, 97–9
8
B
l
a
dd
er in
j
uries, 7
5
t
reatment
,
81
Blunt-ti
p
trocars, 2
7
Bowel in
j
uries, laparoscopic sur
g
er
y
, 21–22,
6
8–
6
9
,
6
8t
,
7
1
access methods and
,
23–2
4
BV
.
S
e
e
Bacterial vaginosis
https://t.me/med1917

In
d
e
x
C
C
ancer.
S
ee Ra
d
ica
l
cancer surgery;
specifi
c
cancers
Car
d
iopu
l
monar
y
exercise (CPX) testin
g
,
88
Car
d
iovascu
l
ar ris
k
ACC/AHA
g
uidelines for, 87, 87t
gy
necolo
gy
patient and, 86–87
C
DL
C
.
S
e
e
Continuous double-loop closur
e
Cefazolin
,
5
Cep
h
a
l
osporins, 1
3
Cervica
l
cancer, surgery, 11, 1
4
Cervica
l
d
i
l
ation,
hy
steroscop
y
, 9
9
Cervica
l
intrae
p
it
h
e
l
ia
l
neo
pl
asia (CIN), 15
Cesarean section, Pomero
y
method of
sterilization at
,
117
Cholecystectomy, laparoscopic, 2
1
C
IN.
S
e
e
Cervical intraepithelial neoplasi
a
Clomiphene, 129
Commun
i
cat
i
on, 63
Continuous
d
ou
bl
e-
l
oop c
l
osure (CDLC), 4
7
Contraception, steri
l
ization an
d
p
re
p
roce
d
ure, 116. See a
l
s
o
Ora
l
contrace
p
tive
p
i
ll
Counselin
g
e
ndometriosis
p
reo
p
erative, 36
h
ysteroscopic preoperative, 9
6
CPX test
i
ng.
S
e
e
Cardiopulmonary exercise
t
est
i
ng
Cryopreservat
i
on, 127
Crysta
ll
oi
d
, a
dh
esion prevention, 52–5
3
C
y
stoscop
y
, 79
D
D
extran
,
100
Dextrose
,
10
0
Dissection, urinar
y
tract in
j
ur
y
prevention
a
nd
,
76–77
Distension media, hysteroscopy, 99–10
2
D
ocu
m
e
n
tation
a
d
verse event, 65
hy
steroscopic sur
g
er
y
, 9
6
urinar
y
tract in
j
ur
y
, 8
2
Dox
y
c
y
cline, 7
E
E
ctopic pregnancy, 110–11
1
E
lective single embryo transfer (eSET), 12
9
E
lectrocautery coagulation, 10
6
E
lectrosurgery, 9
7
b
ipo
l
ar
d
evice
f
or, 97–9
8
E
m
b
ryo trans
f
er tec
h
nique, comp
l
ications
a
ssociate
d
wit
h
, 131–132
E
ndometrial cance
r
l
ymphadenectomy in, 1
7
s
urgery, 1
1
E
n
do
m
et
ri
os
i
s
l
aparoscopic surgery
f
or
a
u
d
it
f
or, 3
8
a
u
d
it resu
l
ts
f
or
,
38–41
,
39
f,
39t
,
41
t
c
om
p
lications of, 34–4
1
dissection for
,
36–37
,
37f
innovation in
,
41
p
atient counseling for, 3
6
rectal involvement/resection and
,
4
0
surgica
l
ris
k
s o
f
, 40, 41
b
surgica
l
tec
h
niques, 36–38
team a
pp
roac
h
to, 37–3
8
n
o
d
u
l
ar, 35, 35
f
s
ur
g
er
y
,
3
4–4
1
c
om
p
lications, 34
m
ana
g
ement,
3
4–
35
s
ymptoms,
34
E
ndoTIP system, laparoscopic surgery, 2
7
E
nterostom
i
es, 3
4
E
ryt
h
ropoietin, 1
4
eSET.
S
e
e
E
l
ective sing
l
e em
b
ryo trans
f
er
Extraperitoneal insuffl
ation,
p
neumo
p
eritoneum an
d
, 2
5
F
F
ascia closure
,
46–4
7
F
ebrile morbidity, hysterectomy and, 3–4
F
ertility, 15.
S
ee als
o
American Fertility
Society; Assisted reproduction
F
ie
ldl
er puncture nee
dl
e,
l
aparoscopic
surgery, 20
F
i
l
s
h
ie c
l
i
p
steri
l
ization, 108, 109t, 117
c
l
ip mi
g
ration, 121
d
ropped “lost” clips and, 12
1
failure of, 108, 109t
operative technique for, 118–120, 118f
operator error an
d
, 112
F
istu
l
a, ra
d
ica
l
gyneco
l
ogica
l
surgery, 1
4
F
istu
l
o
g
ram, 80–8
1
G
Gas embolism,
p
neumo
p
eritoneum and, 25
G
D
T
.
S
e
e
Goal-directed therap
y
Gentam
i
c
i
n, 13
Glycine, 9
7
d
istension me
d
ia, 100
Goa
l
-
d
irecte
d
t
h
erap
y
(GDT), 9
0
G
y
neco
l
o
g
ica
l
cancer
comor
b
i
d
it
y
, 1
2
laparoscopic sur
g
er
y
, 17
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In
d
ex 1
37
s
urgery
r
e
d
ucing comp
l
ications o
f
, 1
6
surgeon an
d
, 17
th
rom
b
osis ris
k
an
d
, 13
G
y
neco
l
o
g
ica
l
onco
l
o
gy
, comp
l
ications in,
–
18
G
y
necolo
g
ical sur
g
er
y
.
S
ee also Hi
g
h-risk
gy
necolo
gy
patient
i
nfection following
a
ntibiotics for
,
choice of
,
5
,
6t
p
at
h
ogenesis o
f
, 1–3
p
revention o
f
, 1–9
i
ntrao
p
erative a
d
verse events an
d
bl
ame an
d
, 65
documentation of
,
62
incident reportin
g
of, 64
root cause analysis for, 64–6
5
p
atient communication and, 6
3
p
ost-operat
i
on, 61–6
6
p
ostoperat
i
ve management, 63
p
reoperat
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ve care, 6
2
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e
l
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h
an
d
, 63
risk assessment specifi
c to, 88–89, 89t
t
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4
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ur
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, 7
5
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j
ur
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, 75–8
2
H
Hasson-style laparoscopy access, 2
6
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4
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ematoma an
d
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5
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3
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in
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v
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4
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,
25
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CG
.
S
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g
onadotropins
Hematoma, laparoscopic surgery, 24–25
Hemorrhage
h
ysteroscopic surgery, 102–10
3
r
a
d
ica
l
cancer surgery comp
l
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d
,
He
p
arin.
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Low-mo
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ar-wei
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t
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epari
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Hernia
abdominal wall trocar
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2
5
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ncisional
,
abdominal wound closure and
,
44
–
45
High-risk gynecology patien
t
assessment of, 84–9
2
a
pproac
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to, 85–89
cl
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or, 86–87
f
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8
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88–89
,
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86–8
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dentifying, 92
management o
f
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ocar
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g
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, 90
p
osto
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p
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8
4
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H
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3
H
RT
.
S
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H
uman c
h
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h
CG),
2
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Hy
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4
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B
V and infectious morbidity after, 4–
5
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p
rophylactic antibiotics for, 3–5
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Hy
steroscopic sterilization, 106
Hy
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clinical practice of, key points for, 104
complications i
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adh
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3
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p
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9
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scale of problem and, 94, 95t
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en
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preparation in, 96
g
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sa
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ase se
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5
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p
ment,
p
ro
p
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8
l
earnin
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phase in, awareness of and,
98
p
at
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on as, 96
iatrogenic, fl
uid overload, 97, 97t
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perating t
h
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f
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Ico
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7
I
CS
I.
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Intrac
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stop
l
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Indi
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https://t.me/med1917

In
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at
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V and post-hysterectomy, 4–
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f
Interceed v.
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,
58f
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studies for, 54–57
laparotom
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mAFS score for
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54
,
55f–56f
pelvic pain, 5
7
I
ntestinal injuries, laparoscopic surgery,
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8–69
I
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2
7
I
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sur
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102
–
103
I
ntrauterine pre
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1
I
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tract
i
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ur
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postoperative diagnosis of, 80–81
preoperat
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9
I
n vitro
f
erti
l
ization
(
IVF
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, 12
7
I
n vitro maturation
(
IVM
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, 12
7
Ische
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M
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IVF
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S
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In vitro fertilization
IVM
. Se
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In vitro maturation
IVP.
S
ee Intravenous pyelogram, urinary
tract injury
L
aparoscop
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S
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l
s
o
specifi
c
access
methods
a
bd
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f
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9
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benefi
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blind/closed
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22
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injury an
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a
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h
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s, 23–24
c
h
o
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1
c
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ose
d
, 22, 2
8
op
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.
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23–2
6
com
p
lications, 67
e
ndometriosis and
,
34–41
l
aparotomy and, 26
m
inimizing risk of, 26–2
7
counseling, 28–29
d
iagnostic, 21
e
n
do
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it
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, 39t, 41
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lications of, 34–4
1
dissection for
,
36–37
,
37f
innovation in
,
41
p
atient counseling for, 3
6
rectal involvement/resection and, 4
0
surgical risks of, 40, 41b
surgica
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tec
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niques, 36–38
team approac
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to, 37–3
8
entr
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niques, 21–22
c
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20–29
gy
necolo
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ical cancer, 17
Hasson-st
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h
ospital readmissions, 26
h
ybrid visual/closed, 22
i
n
j
ur
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8
a
ccess-re
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ate
d
, 21, 23–24
classifi
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ntr
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-related, 21–2
2
m
anagement of, 69–7
1
p
revention of, 69–7
1
i
nstruments for
,
use of newer
,
2
7
Intergel and studies with, 54–5
7
i
ntestinal injury and, 21–22, 68–69
l
aparotomy an
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/
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l
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f
, 2
6
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20
l
iti
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6
o
p
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,
28
c
losed
v
.
,
23–2
6
pneumoperitoneum complications and,
2
5
r
ecommen
d
ations
f
or, 28
risk factors, identifi
cation of, 26–27
s
teri
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rou
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, 11
7
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rocar, 23–2
6
t
u
b
a
l
steri
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,
20
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reteric in
j
ur
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and, 7
1
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In
d
ex 1
39
u
rinary injury an
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h
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u
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vascu
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1
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h
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s, 24
Verres nee
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23–26
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, 27
visceral in
j
ur
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and, 21
visual/o
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2
L
aparoscopic tubal occlusion, 10
6
L
aparotom
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comp
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Interge
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h
, 53–54
l
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/
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laparoscopic sur
g
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v
.
,
20
s
terilization throu
g
h, 11
7
L
eiomyomas.
S
ee Submucous leiomyoma
s
L
itigation
laparoscopic surgery, 26
s
terilization failure, 113–11
4
u
r
i
nary tract
i
n
j
ury, 75
L
ow-mo
l
ecu
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ar-weig
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t
h
eparin, 14
Ly
mp
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a
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y
, en
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ometria
l
cancer,
7
M
M
AS
.
S
e
e
Minimal-access sur
g
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M
axon.
S
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e
Polyglyconat
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M
etabolic equivalent levels (METs), 87–88
M
ethylene blue, 7
9
Met
r
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ni
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ole
BV
, 5
i
n
f
ection, 13
T
OP
,
7
M
E
T
s.
S
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b
o
l
ic e
q
uiva
l
ent
l
eve
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M
inimal-access sur
g
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(MAS), 94
M
iso
p
rostol, 9
9
Modifi
ed AFS (mAFS) score, 54, 55f–56f
M
ultiple pregnancies, 129
r
is
k
o
f
, minimizing, 132–13
3
M
yocar
d
ia
l
isc
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emia, 89–90
N
Novafi
l.
S
e
e
Pol
y
butester
O
O
H
SS
.
S
ee Ovarian hyperstimulation
syndrome
Oocyte retrieval, 130
Operator error, steri
l
ization
f
ai
l
ure an
d
,
Optica
l
trocars,
l
aparoscopic sur
g
er
y
, 27
Ora
l
contrace
p
tive
p
i
ll
, 16
O
var
i
an cancer
o
varian stimulation and risk of, 130
s
urgery, 1
1
Ovarian
h
yperstimu
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OHSS
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, 127–12
9
p
revention, 128–12
9
r
isk factors for develo
p
ment of, 128
r
isk of, decreasin
g
, 13
2
O
varian stimulation, complications
a
ssociated with
,
127–130
cancer risks as, 130
multiple pregnancies as, 12
9
OHSS as, 127–12
9
P
PAS. See Posta
b
orta
l
se
p
si
s
Patients.
S
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h-risk
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necolo
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communication with
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6
3
s
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,
11
5
P
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Po
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P
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vis, in
f
ection
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hy
sterectom
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3
TOP an
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p
revention o
f
,
7
P
erforation
h
y
steroscop
y
, 99
laparoscopic surgery and abdominal wall,
29
P
eritoneum, abdominal wall closure and
c
losing, 45–46
P
neumoper
i
toneum, 22
l
aparoscopy, comp
l
ications re
l
ate
d
to, 25
Polybutester (Novafi
l), 4
8
Pol
y
dioxanone (PDS), 47
Pol
yg
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8
Polyglyconate (Maxon), 47
Polypropylene
abdominal wound failure, acute and, 48
f
ascia closure, 4
7
Pomeroy met
h
o
d
o
f
steri
l
ization at cesarean
sect
i
on, 117
Posta
b
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se
p
sis (PAS), 7
P
re
g
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.
S
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s
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Mu
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tip
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g
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Termination of pre
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ecto
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1
factors identifi
ed to alter cumulative
probability of, after sterilization, 11
0
i
ntrauterine, steri
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s
teri
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ris
k
o
f
, 10
8
Preimp
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antation
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enetic
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ia
g
nosis, 12
7
Preventa
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h
arm
,
6
1
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4
0
In
d
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R
Ra
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cancer surgery, 1
1
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outcome o
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2
Ra
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5
Rectum, endometriosis laparoscop
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and
involvement/resection of
,
40
Ringer’s solution, lactated, 54
mAFS score for
,
54
,
55f–56f
Risk management, 61, 66
Root cause analysis, 6
1
a
d
verse event, 64–6
5
bl
ame an
d
, 6
5
p
reo
p
erative care, 62
S
Saline
,
100
Versapoint operation in, 100, 101f, 102
f
Sexual dysfunction, gynecological cancer
surgery and, 1
6
Skin closure, abdominal wound closure
a
n
d
, 48
Sor
b
ito
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, 9
7
d
istension me
d
ia, 100
S
p
erm retrieva
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, 13
1
Step Ra
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Expan
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S
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stem,
l
aparoscopic
sur
g
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,
2
7
S
terilization.
S
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Filshie cli
p
sterilization; Hysteroscopic
sterilization
f
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ow-up, 120–12
1
h
ysteroscopic, 106
menstrua
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c
y
c
l
e an
d
re
l
ation o
f
, 116
Pomero
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met
h
o
d
o
f
, at cesarean section,
7
p
ost
p
artum, 11
6
–117
prepregnancy testing and, 116
preprocedure contraception and,
1
6
t
echniques, 106, 107
t
l
aparoscopy, 11
7
l
aparotomy, 11
7
t
imin
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o
f
operation, 116–117
t
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b
a
l
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S
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Cana
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ian
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ata set examining, 107–108,
08t, 11
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f
ter, 110–11
1
evi
d
ence o
f
, 115, 115
t
assess
i
n
g
, 114–115
i
dentif
y
in
g
, 114–115
factors infl
uencing, 110
F
ilshie clip method and, 108, 109t
i
ntrauterine pregnancy after, 110–11
1
mechanism of, 111t, 113–11
4
medicolegal consequences of, 113–114
n
eg
l
igence an
d
, 113–11
4
n
onneg
l
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, 113–114
o
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, 11
operator experience/trainin
g
an
d
, 12
0
p
atient selection and, 11
5
r
ates
,
10
7–
109
r
isk, minimizing, 106–121
Submucous leiomyomas, 95, 95
t
Systemic infl
ammatory responses, 1, 2t
T
a
m
o
xi
fe
n
gy
neco
l
o
g
ica
l
cancer an
d
, 16
th
rom
b
osis an
d,
1
3
Termination of pre
g
nanc
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(TOP),
1
antibiotics, proph
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lactic for, 8–9
i
nfection associated with, prevention of,
7
–8
pe
l
vic in
f
ection prevention an
d
, 7
T
h
r
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m
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s
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neco
l
o
g
ica
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d
, 1
3
r
a
d
ica
l
cancer sur
g
er
y
comp
l
ications an
d
,
–
1
4
Tinidazole
,
5
T
OP.
S
ee Termination of pre
g
nanc
y
Transfusion, radical cancer surger
y
c
omplications and, 1
4
Trocar laparoscopy access, 26
abdominal wall, hernia at site of, 25
b
owe
l
injuries an
d
, 23–2
4
h
ematoma an
d
, 24–25
morta
l
it
y
, 2
3
s
a
f
et
y
, 23
u
rinar
y
in
j
uries and, 24
vascular injuries and, 24
woun
d
in
f
ection, 25
Tr
oca
r
s.
Se
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B
l
unt-tip trocars; Optica
l
t
r
oca
r
s
Tu
b
a
l
occ
l
usion
coa
g
ulation-based, 11
2
follow-up for uncertaint
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in, 120–121
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In
d
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1
l
aparoscopic, 106
mec
h
anica
l
, 112
Tu
b
a
l
steri
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l
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Tu
b
a
l
sur
g
ica
l
excision, 106
U
U
reteric in
j
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i
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laparoscopic surgery, 7
1
locations
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77f
t
reatment, 8
1
U
ret
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ra
l
injury, 7
5
t
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1
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l
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,
24
U
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tract, 75–82
U
rinary tract injuries
causes
,
7
6
d
etecting, 79–80
d
ocumentation, 8
2
i
ntraoperative
d
iagnosis o
f
, 79–8
0
l
aparoscopic surgery, 6
9
l
itigation an
d
, 75
postoperative
d
ia
g
nosis o
f
, 80–81
p
revention, 76–79
r
isk factors
,
76
s
ites
,
7
6
t
reatment
,
81
t
ypes, 7
6
U
S CREST study, 107–108, 110
V
Va
gi
na.
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Videoconferencing, gynecological oncology
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25
Wound closure.
S
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4
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