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17 - 
. (p
 
        
     
13
- 
        

-IIIF3-
FF1-F
-I F0-F
F3-F4.
       
       
     .   
       
     8 (p    

8
5
6
7
9
12
15
10
2
2
5
20
0%
20%
40%
60%
80%
100%

(n=19)
-I
(n=19)
-II
(n=26)
-III
(n=37)
F3-F4
F1-F2
F0
https://t.me/med1917
82
 18 - 
p.
 
        
       

      
       
        
      

         
         
(2006.01) A61K 49/06 (2006.01)     
     
13
-  CUM30<5,65% -
  F    CUM -   F4

        

0%
20%
40%
60%
80%
100%
Норма (n=19)
ДП-I (n=19)
ДП-II (n=26)
ДП-III (n=37)
17
17
21
17
2
2
5
20
F0-F1-F2
F3-4
https://t.me/med1917
83
       
 
        
        

     N    

  
13
-

     
 .
Пример 1.   - 
2
        
        -
MELD-15, APRI 2,13 (K74.6).
 - 
      
 
-

     
-1.


RW ( )  BsAg (-) - 
HCV(+) 
          
-  
https://t.me/med1917
84
          -  

      
- 
9

12

- - 
9

    
    - 
       


    

     

    N    
 
13
- N    
   
13
-    
19.
19 - 
13
-
13
-
https://t.me/med1917
85
Пример 2.  ., 23 -173 -69 -23,07 
2
    b  

5
      F 
METAVIR, A)
.
         HCV-
  b. .
   bsAg HCV  
.
       
- 
30.09.2016
    30.09.2016    
 
1.10.2016

 
 (F0  (A0) 20).
20 -  
https://t.me/med1917
86

13
-
13
-
21.
21 - 
13
-
    N       

Пример 3. - - - 
2
.
--
 
 -.
    

https://t.me/med1917
87
    - 
            -
  

  38   -

38 -  .




F4
S2
F0 S0

/
6-/

/
11-/

/
35-


10-


3-


33-

1,0
   

  

1b
HCV  - 500 000

-

115x10
9

180-
9


13
- 22.

    
13
-     

https://t.me/med1917
88
22 - 
13
-
Пример 4.    /
2
.
  
        HCV-
     b    400
 (2015).
    - -
-
 - 

: F0 A0.
F0.
    (31.08.16):    
  
 :     b  
(<500000/      F 
https://t.me/med1917
89
    
13
- 
23.
23 - 
13
-


13
           
       

https://t.me/med1917
90

      
, 
  
        
      
        
        
  [31, 48, 76, 130, 159, 171].
      
 
         
       
     [88]  
       [29,
104, 137, 142].
       
     
        
 [82, 83, 106, 164, 172, 174].   
       
       
      
.
     
       
  
https://t.me/med1917