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

     

       
 -    
 -   
.
           
     
       
     
    

 -  -       
        
         
        
 
, .

    -

 
       
      
    
13
- 
https://t.me/med1917
12

      



 126     
         
      
 
    38   24
, 4  ;    
174 63 111 .
https://t.me/med1917
13



1.1 
-
 
 

            
     
  -    

-
          
 149   Ali A. Mokdad et al 
128].
     
        
      
 [85, 145]



  
82].
         

https://t.me/med1917
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  
       

[79, 100, 107, 165].
-  
        
[83, 106, 125, 163, 164,
172, 174] 
-
         
166].

      
      
-
108].
        
     
     
       
     
(Potential Years of Life Lost      
-37].
        

 [7, 18, 83, 109, 127, 128]      
)
[22, 35, 36, 46].
https://t.me/med1917
15
        
         
       
         

      
        
1, 2, 5].

 EASL      
        
       
    
 [97].
     
      
        
       -  
      
      
        
 -      
25, 82, 149].
      -      
           
          
 [166]
      
 
https://t.me/med1917
16
97,

         
              
100000 166].
      -
     
       

     
        
      
  
 11].

      [86]  

     
     -    
 [33, 74,
81, 105, 112, 131]
       
        21, 26 
      99, 129 

   31, 48, 76, 130, 159, 171  
    -   
22, 23, 48, 59, 134].
https://t.me/med1917
17
         


        
     
      

     
       
 
1. 
2. 
3.       

4.    - - -6),
       
    - 
       
      
-2
-52,
58, 115, 151, 169].
     E.        
    
   
   -     
        
https://t.me/med1917
18
  -1 (     
  [84, 153]   
        
      , 
 [153, 161]       


        
80, 139, 143]. ,
, 
 
   

 -       
        
     

      
[90       
     
  Noth (  Notch  
      
) [119]. 
    
       

       
[121, 122, 136, 152, 160]
 -1    
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    152]  
       

     VEGF   
growth factor) [148      
      
.
1.3 
       

1.        

2.       

3.     

4. :
;
;
;
-;
: APRI AST.
to Platelet Ratio Index), FIB;
5. :
- CAP

(Controlled attenuation para   
;
- -.
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6.        MELD
(model for endstage liver disease), FibroFast    FibroIndex
   Hepascore    NAFLD
score -Lille 
7. -
        

  -   ) [98, 146].
       
       
      3, 10, 35, 40, 53  
         
     
35, 40]       
         
[10, 53].
      
         
 -
       

16, 32, 50, 60, 146].
      
       
          
   95, 135, 144].   
17, 158].
        
       
https://t.me/med1917