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Pain medicine is now a medical specialty in its own
right. Although the multidisciplinary approach
is the cornerstone of modern pain medicine, by
far the majority of patients with acute, chronic
or cancer pain are currently under the care of an
individual discipline. Different medical specialists
or allied health care teams provide services to pain
patients following the approach and traditions
of their own discipline. With greater advances in
medical science and the growing expectancy of
patients, these teams need to work in collaboration
to provide good quality care with expertise and
complexity. is textbook serves as a platform for
different medical specialists and allied health care
professionals from which to describe, discuss and
share their experience in delivering care to pain
patients. Experts in the field of pain medicine
from different parts of the world have jointly
contributed to the Chapters in this textbook.
e Editors would like to express their utmost
appreciation for the time and hard work of all
contributors and co-contributors who have made
this book possible.
e primary aim of this textbook is to serve as a
comprehensive basic textbook for pain medicine
physicians in their preparation for their higher
qualification examination. e book also serves as
a reference book for other medical specialists and
allied health care professionals who need to take
care of patients with acute, chronic or cancer pain.
e Chapters are organised into five Sections. e
book commences with a Section dedicated to basic
science related to pain mechanisms, psychology,
assessment, statistical analysis and ethics. is is
followed by a Section which contributes to the
detailed discussion of different types of clinical pain
condition. e other three Sections are dedicated
to the different approaches used to manage pain,
namely: pharmacological treatment, interventional
procedures and other specialised techniques.
is book is intended to provide a medium to
facilitate and further enhance the quality of our care
to the patients who suffer from acute, chronic or
cancer pain. We hope that readers will find the book
informative and helpful in their clinical practice.
Preface
Siu Lun TSUI
https://t.me/medicina_free
https://t.me/medicina_free
EDITORS
Dr. Siu Lun TSUI
MBBS, MD, FFPMANZCA, FANZCA, FHKCA,
FHKAM (Anaesthesiology), Dip Pain Mgt (HKCA)
Consultant Anaesthetist & Head,
Division of Pain Medicine,
Department of Anaesthesiology,
Queen Mary Hospital, Hong Kong SAR
Honorary Clinical Associate Professor,
Department of Anaesthesiology,
e University of Hong Kong
Department of Anaesthesiology,
Queen Mary Hospital,
Room 43, 2/F, F Wing, Main Block,
Queen Mary Hospital, 102 Pokfulam Road,
Hong Kong SAR
tsuisl@ha.org.hk
Dr. Phoon Ping CHEN
MBBS, FFPMANZCA, Dip Pain Mgt (HKCA),
FHKAM, FHKCA, FANZCA, MHA
Consultant & Chief of Service,
Department of Anaesthesiology & Operating
Services,
Alice Ho Miu Ling Nethersole Hospital & North
District Hospital, Hong Kong SAR
Honorary Associate Professor, Department
Anaesthesia & Intensive Care,
e Chinese University of Hong Kong
Department of Anaesthesiology & Operating
Services,
Alice Ho Miu Ling Nethersole Hospital,
11 Chuen On Road, Tai Po, Hong Kong SAR
chenpp@ha.org.hk
Associate Professor Jacobus Kwok Fu NG
MBChB, MD, FANZCA, FHKCA, FHKAM
(Anaesthesiology), Dip Pain Mgt, MBA
Associate Professor,
Department of Anaesthesiology and Department
of Pharmacology & Pharmacy,
e University of Hong Kong,
Room 424, Block K, Queen Mary Hospital,
102 Pokfulam Road, Hong Kong SAR
jkfng@hku.hk
CONTRIBUTORS & CO-CONTRIBUTORS
(in alphabetical order)
Dr. Gordon K.H. AU
MBBS (London), FRCR, FHKCR, FHKAM
Chief of Service,
Department of Clinical Oncology,
Queen Mary Hospital, Hong Kong SAR
Dr. Geoff Alexander BELLINGHAM
MD, FRCPC
Clinical Fellow,
Wasser Pain Management Clinic,
Mount Sinai Hospital, Toronto, Ontario, Canada
Dr. Mary CARDOSA
MB, BS, MMed, FANZCA, FFPMANZCA, FAMM
Consultant Anaesthesiologist,
Hospital Selayang, Selangor, Malaysia
Head of Subspecialty (Pain Medicine),
Ministry of Health, Malaysia,
54, Lorong Burhanupdin Helmi 6, Taman Tun
Dr. Ismail, 60000 Kuala Lumpur, Malaysia
Editors, Contributors
& Co-contributors
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xiv Editors, Contributors & Co-contributors
Dr. George CHALKIADIS
MBBS, DA (Lon), FANZCA, FFPMANZCA
Staff Anaesthetist and Pain Medicine Specialist,
Head, Children’s Pain Management Service,
Department of Paediatric Anaesthesia and
Pain Management, Royal Children’s Hospital,
Flemington Road, Parkville VIC 3052, Australia
Clinical Associate Professor,
University of Melbourne Murdoch Children’s
Research Institute, Australia
george.chalkiadis@rch.org.au
Professor Chetwyn C.H. CHAN
PhD
Professor,
Applied Cognitive Neuroscience Laboratory,
Head, Department of Rehabilitation Sciences,
e Hong Kong Polytechnic University Hung
Hom, Kowloon, Hong Kong SAR
Chetwyn.Chan@inet.polyu.edu.hk
Dr. Simon K.C. CHAN
MBBS, FANZCA, FHKCA, FHKAM, MHSM, Dip Pain
Mgt (HKCA)
Honorary Associate Professor, Consultant
Department of Anaesthesia & Intensive Care,
e Chinese University of Hong Kong,
Prince of Wales Hospital, Shatin,
Hong Kong SAR
simonkcchan@cuhk.edu.hk
Dr. Anne Miu Han CHAN
MBBS, FANZCA, FFPMANZCA, FHKCA, FHKAM,
Dip Pain Mgt
Senior Medical Officer, Doctor in Charge of Pain
Service,
Princess Margaret Hospital
Department of Anaesthesia,
Princess Margaret Hospital, Lai Chi Kok,
Kowloon, Hong Kong SAR
chanmha@ha.org.hk
Dr. Phoon Ping CHEN
MBBS, FFPMANZCA, Dip Pain Mgt (HKCA),
FHKAM, FHKCA, FANZCA, MHA
Consultant & Chief of Service,
Department of Anaesthesiology & Operating
Services,
Alice Ho Miu Ling Nethersole Hospital & North
District Hospital
Honorary Associate Professor,
Department Anaesthesia & Intensive Care,
e Chinese University of Hong Kong
Department of Anaesthesiology & Operating
Services,
Alice Ho Miu Ling Nethersole Hospital,
11 Chuen On Road, Tai Po, Hong Kong SAR
chenpp@ha.org.hk
Assistant Professor Chi Wai CHEUNG
MBBS, FHKCA, FHKAM (Anaesthesiology), Dip Pain
Mgt (HKCA)
Assistant Professor,
Department of Anaesthesiology,
e University of Hong Kong
Department of Anaesthesiology,
e University of Hong Kong,
Room 424, Block K, Queen Mary Hospital,
102 Pokfulam Road, Hong Kong SAR
cheucw@hkucc.hku.hk
Mr. Leo Chin Ting CHEUNG
MSc in Health Care (Physiotherapy), BSc in
Physiotherapy, Dip Epidemiology and Biostatistics
Senior Physiotherapist,
Department of Physiotherapy,
Alice Ho Miu Ling Nethersole Hospital, 11
Chuen On Road, Tai Po, Hong Kong SAR
cheungchinting@yahoo.com.hk
Professor Kenneth M.C. CHEUNG
MBBS, MD, FRCS, FHKCOS, FHKAM (Orth)
Clinical Professor,
Deputy Chief, Division of Spine Surgery,
LKS Faculty of Medicine,
e University of Hong Kong
Honorary Consultant Orthopaedic Surgeon,
Department of Orthopaedics & Traumatology,
Queen Mary Hospital, 102 Pokfulam Road,
Hong Kong SAR
ken-cheung@hku.hk
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xv
Editors, Contributors & Co-contributors
Dr. Ping Hong CHIN
MB, FHKAM (Orthopaedic Surgery), LMCHK
Consultant, Department of Orthopaedics &
Traumatology,
Queen Elizabeth Hospital, 30 Gascoigne Road,
Kowloon, Hong Kong SAR
Dr. Christopher Ping Wing CHU
BMedSci, BMBS, FRCP (Canada), FHKAM, FHKCA,
MBA
Senior Medical Officer,
Department of Anaesthesiology and Operating
Services,
Alice Ho Miu Ling Nethersole Hospital & North
District Hospital, Hong Kong SAR
Dr. Ming Chi CHU
MBBS, FHKCA, FANZCA, FFPMANZCA, Dip Pain
Mgt (HKCA)
Associate Consultant,
Department of Anaesthesia and Intensive Care,
Prince of Wales Hospital, Shatin,
Hong Kong SAR
chu0079@cuhk.edu.hk
Dr. Tak Yi CHUI
MBBS (HK), MRCP (UK), FRCP (Glasgow), FHKCP,
FHKAM (Medicine)
Chief of Service (Geriatrics and Rehabilitation),
Haven of Hope Hospital, Hong Kong SAR
Physician-in-Charge, Chronic Pain Rehabilitation
Programme,
Haven of Hope Hospital
Haven of Hope Hospital, 8 Haven of Hope Road,
Tseung Kwan O, Hong Kong SAR
chuity@ha.org.hk
Dr. Edmond Kin Nam CHUNG
MBBS, Dip Pain Mgt (HKCA), FHKCA, FHKAM
Formerly Director of Pain Services
Department of Anaesthesiology & Operating
Services,
Alice Ho Miu Ling Nethersole Hospital & North
District Hospital, Hong Kong SAR
Professor Joanne W.Y. CHUNG
RN, PhD
Professor,
School of Nursing,e Hong Kong Polytechnic
University, Hong Kong SAR
hsjchung@inet.polyu.edu.hk
Associate Professor Milton L. COHEN
MBBS, MD, FRACP, FAFRM, FFPMANZCA
Consultant Physician,
Rheumatology and Pain Medicine,
St Vincent’s Campus, Sydney, NSW, Australia
Conjoint Associate Professor of Medicine,
University of New South Wales
St Vincent’s Medical Centre, 376-382 Victoria
Street, Darlinghurst NSW 2010, Australia
M.Cohen@unsw.edu.au
Dr. Philip FINCH
MBBS, FFARCS, DRCOG, FFPMANZCA, FIPP
Adjunct Professor,
Murdoch University
Perth Pain Management Centre, PO Box 641,
South Perth 6951, Western Australia
pfinch@iinet.net.au
Dr. Amy Shuk-Man FUNG
BSocSc, MSocSc, PhD (HK)
Head,
Hong Kong West Cluster Clinical Psychological
Services, Hospital Authority
Head & Senior Clinical Psychologist,
Department of Clinical Psychology,
Queen Mary Hospital, 102 Pokfulam Road,
Hong Kong SAR
fungsm@ha.org.hk
Professor Tony GIN
MD, FANZCA, FRCA, FHKAM
Chairman and Chief of Service
Department of Anaesthesia and Intensive Care,
Chinese University of Hong Kong,
Prince of Wales Hospital, Shatin,
Hong Kong SAR
tgin@cuhk.edu.hk
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xvi Editors, Contributors & Co-contributors
Dr. C. Roger GOUCKE
FANZCA, FFPMANZCA, FAChPM (RACP)
Clinical Associate Professor,
School of Medicine and Pharmacology,
University of Western Australia and Head,
Department of Pain Management,
Sir Charles Gairdner Hospital,
Perth WA 6009, Australia
Roger.Goucke@health.wa.gov.au
Dr. Chi Tim HUNG
MBBS, FANZCA, FHKCA, FHKAM (Anaesthesiology),
Dip Pain Mgt (HKCA)
Previously Consultant Anaesthetist and Head of
Pain Management Team,
Queen Elizabeth Hospital
Honorary Clinical Associate Professor,
Department of Anaesthesiology,
University of Hong Kong,
Room 902, S Block, Queen Elizabeth Hospital,
30 Gascoigne Road, Kowloon, Hong Kong SAR
cthung@ha.org.hk
Dr. Kwan Ngai HUNG
MBBS, FRCS (Edin), FCSHK, FHKAM (Surgery)
Consultant and Head,
Department of Neurosurgery,
Queen Mary Hospital, 701 Administrative Block,
102 Pokfulam Road, Hong Kong SAR
hungkn@hkucc.hku.hk
Professor Michael G. IRWIN
MBChB, MD, FRCA, FHKCA, FHKAM
(Anaesthesiology), DA
Professor and Head,
Department of Anaesthesiology,
e University of Hong Kong
President,
e Hong Kong College of Anaesthesiologists
Department of Anaesthesiology,
Room 424, Block K, Queen Mary Hospital,
102 Pokfulam Road, Hong Kong SAR
mgirwin@hkucc.hku.hk
Dr. Kok Eng KHOR
MBBS, MMed (Pain Med), Dip Musc Med, FAFMM,
FANZCA, FAChPM (RACP), FFPMANZCA
Director of Pain Management,
Prince of Wales Hospital, Sydney, Australia
kekhor@bigpond.net.au
Dr. Anne KWAN
MBBS, FANZCA, FFPMANZCA, FHKCA, FHKAM,
Dip Pain Mgt, Dip Acup, Dip Epi & Stat, M Pal Care
Chief of Service and Consultant Anaesthesiologist,
United Christian Hospital, Hong Kong
Director of Kowloon East Management Centre,
Adjunct Associate Professor,
e Chinese University of Hong Kong,
Department of Anaesthesiology and Pain
Medicine, 130 Hip Wo Street, Kwun Tong,
Kowloon, Hong Kong SAR
annekwan@ha.org.hk
Dr. Hau Yan KWOK
MBChB, FHKAM (Orthopaedic Surgery), FHKCOS,
FRCSE (Ortho)
Associate Consultant and Honorary Clinical
Assistant Professor,
e University of Hong Kong
e University of Hong Kong Medical Centre,
Department of Orthopaedics & Traumatology,
Queen Mary Hospital
5/F, Professorial Block, Queen Mary Hospital,
102 Pokfulam Road, Hong Kong SAR
hykwok@hku.hk
Professor Chak Sing LAU
MBChB, MD (Hons), FRCP, FHKCA, FHKAM (Internal
Medicine)
Chief of Rheumatology,
University of Dundee
University Division of Medicine & Clinical
erapeutics,
Ninewells Hospital and Medical School,
Dundee, United Kingdom
c.lau@dundee.ac.uk
Mr. Anthony Wing Keung LAU
PD in Physiotherapy, Post-registration Cert in Spinal
Manipulative erapy, PD in Acupuncture, PD in OSH,
MHA, BSc (Econ)
Department Manager,
Department of Physiotherapy,
Alice Ho Miu Ling Nethersole Hospital,
11 Chuen On Road, Tai Po, Hong Kong SAR
lauwka@ha.org.hk
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xvii
Editors, Contributors & Co-contributors
Dr. Libby Ha Yun LEE
MBBS, FANZCA, FHKCA, FHKAM, Dip Pain Mgt
Associate Consultant Anaesthetist,
Supervisor of Training in Pain Medicine,
Queen Mary Hospital, Hong Kong
Honorary Clinical Assistant Professor,
Department of Anaesthesiology,
e University of Hong Kong,
Queen Mary Hospital, 102 Pokfulam Road,
Hong Kong SAR
libbylee@hkucc.hku.hk
Dr. Tsun Woon LEE
MBBS, FFARACS, FANZCA, FFPMANZCA, FHKCA,
FHKAM (Anaesthesiology), Dip Pain Mgt
Service Director (Clinical & Ambulatory Care),
NT West Cluster, Hospital Authority,
Hong Kong
Hospital Chief Executive,
Pok Oi Hospital, Au Tau, Yuen Long,
Hong Kong SAR
leetw@ha.org.hk
Professor Peter Wing Ho LEE
BSocSc, MSocSc, PhD (HK)
Head,
Clinical Health Psychology Programme,
Department of Psychiatry,
e University of Hong Kong
Honorary Consultant Clinical Psychologist,
Department of Clinical Psychology,
Queen Mary Hospital, 102 Pokfulam Road,
Hong Kong SAR
hrmclwh@hkucc.hku.hk
Dr. Carina Ching Fan LI
MBBS, FANZCA, FHKCA, FHKAM (Anaesthesiology),
Dip Pain Mgt
Pain Management Clinic,
Hong Kong Sanatorium & Hospital, 4/F,
Central Block, 2 Village Road, Happy Valley,
Hong Kong SAR
carinali@hksh.com
Dr. Theresa Tak Lai LI
MBBS, FANZCA, FHKCA, FHKAM, Dip Pain Mgt
Senior Medical Officer,
Deputy Team Head,
Pain Management Team,
Department of Anaesthesiology & OT Services,
Queen Elizabeth Hospital
1/F, Block D, 30 Gascoigne Road, Kowloon,
Hong Kong SAR
litl@ha.org.hk
Dr. Rico K.Y. LIU
MBBS (Syd), FRCR, FHKCR (Clinical Oncology,
Palliative Medicine), FHKAM (Rad), FAChPM, MSocSc
(Counselling) (HKU)
Associate Consultant,
Department of Clinical Oncology,
Queen Mary Hospital,
Honorary Clinical Assistant Professor,
e University of Hong Kong
Department of Clinical Oncology,
1/F, Professorial Block, Queen Mary Hospital,
102 Pokfulam, Hong Kong SAR
liuky@ha.org.hk
Dr. Raymond S.K. LO
MBBS, MD, MHA, Dip Geri Med, Dip Palliat Med,
FRCP, FHKAM
Cluster Co-ordinator,
Hospice and Palliative Care,
New Territories East Cluster
Chief of Service,
Bradbury Hospice
Consultant,
Geriatrics and Palliative Medicine,
Shatin Hospital and Bradbury Hospice,
17 A Kung Kok Shan Road, Shatin,
HONG KONG SAR
Dr. Alice K.Y. MAN
FANZCA, FHKCA, FHKAM, Diploma in Pain Medicine
(HKCA), Dip Pain Mgt, DFM (Monash)
Honorary Assistant Professor,
Associate Consultant,
Department of Anaesthesia & Intensive Care,
Prince of Wales Hospital, Shatin,
Hong Kong SAR
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xviii Editors, Contributors & Co-contributors
Associate Professor Kwok Fu Jacobus NG
MBChB, MD, FANZCA, FHKCA, FHKAM
(Anaesthesiology), Dip Pain Mgt, MBA
Associate Professor,
Department of Anaesthesiology and Department
of Pharmacology & Pharmacy,
e University of Hong Kong,
Room 424, Block K, Queen Mary Hospital
Authority, 102 Pokfulam Road, Hong Kong SAR
jkfng@hku.hk
Associate Professor Michael K. NICHOLAS
PhD
Director,
ADAPT Pain Management Programme
Pain Management & Research Centre
University of Sydney at Royal North Shore
Hospital, St Leonards NSW 2065, Australia
miken@med.usyd.edu.au
Associate Professor Philip Wenn Hsin PENG
MBBS, FRCPC
Director,
Anesthesia Chronic Pain Program,
University Health Network and Mount Sinai
Hospital
Director of Research,
Wasser Pain Management Center,
Mount Sinai Hospital
Associate Professor,
Department of Anesthesia, University of Toronto,
Toronto Western Hospital, McL 2-405 399
Bathurst Street, Toronto, ON M5T 2S8.
Philip.peng@uhn.on.ca
Associate Professor Philip SIDDALL
MBBS, MM (Pain Mgt), PhD, FFPMANZCA
Clinical Associate Professor,
Pain Management Research Institute,
University of Sydney,
Royal North Shore Hospital,
Sydney, Australia
Pain Management Research Institute,
Royal North Shore Hospital, St Leonards,
NSW 2065, Australia
phils@med.usyd.edu.au
Dr. Kai On SUN
Consultant,
Department of Anaesthesia,
Kwong Wah Hospital, Kowloon, Hong Kong SAR
Ms. Connie Y.Y. SUNG
Department of Rehabilitation Sciences,
e Hong Kong Polytechnic University, Hung
Hom, Kowloon, Hong Kong SAR
Dr. Henry Ka Fai TONG
Associate Consultant,
Department of Anaesthesia,
Kwong Wah Hospital, Kowloon, Hong Kong SAR
Dr. Siu Lun TSUI
MBBS, MD, FFPMANZCA, FANZCA, FHKCA,
FHKAM (Anaesthesiology), Dip Pain Mgt (HKCA)
Consultant Anaesthetist & Head,
Division of Pain Medicine,
Department of Anaesthesiology,
Queen Mary Hospital, Hong Kong SAR
Honorary Clinical Associate Professor,
Department of Anaesthesiology,
e University of Hong Kong
Department of Anaesthesiology,
Queen Mary Hospital, Room 43,
2/F, F Wing, Main Block, Queen Mary Hospital,
102 Pokfulam Road, Hong Kong SAR
tsuisl@ha.org.hk
Professor Ramani VIJAYAN
MBBS, DA (Lon), FFARCS (I), FFARCS (Eng), FRCA,
FANZCA, FAMM
Professor,
Department of Anaesthesiology,
Faculty of Medicine, University of Malaya,
Kuala Lumpur, Malaysia
President,
Malaysian Association for the Study of Pain
Department of Anaesthesiology,
University of Malaya,
50603 Kuala Lumpur, Malaysia
ramani@um.edu.my
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xix
Editors, Contributors & Co-contributors
Assistant Professor Gordon T.C. WONG
MBBS, BSc (Med), FANZCA, FHKCA, FHKAM
(Anaesthesiology)
Department of Anaesthesiology,
e University of Hong Kong, Room 424,
Block K, Queen Mary Hospital,
102 Pokfulam Road, Hong Kong SAR
Dr. Steven H.S. WONG
MBBS, FANZCA, FHKCA, FHKAM (Anaesthesiology),
Dip Pain Mgt
Consultant Anaesthetist,
Head of Pain Management Team,
Department of Anaesthesiolgy, Queen Elizabeth
Hospital
Honorary Clinical Associate Professor,
Faculty of Medicine,
e University of Hong Kong
President,
e Society of Anaesthetists of Hong Kong
Department of Anaesthesiology,
Queen Elizabeth Hospital, 30 Gascoigne Road,
Kowloon, Hong Kong SAR
wonghss@ha.org.hk
Dr. Paul WRIGLEY
MBBS, MM (Pain Mgt), PhD, FANZCA, FFPMANZCA
Senior Lecturer,
Senior Staff Specialist in pain medicine
Pain Management Research Institute,
Division of the Kolling Institute,
University of Sydney,
Royal North Shore Hospital, St Leonards, NSW,
Australia 2065
paul.wrigley@sydney.edu.au
Dr. Jacqueline YAP
MBBS, FANZCA, FFPMANZCA, FHKCA, FHKAM
(Anaesthesiology), Dip Pain Mgt, MSc (Epidemiology &
Biostatistics), MHSM
Consultant,
Department Anaesthesia,
Caritas Medical Centre, Hong Kong SAR
yapcm@ha.org.hk
Dr. Arthur YUE
MBBS
Medical Officer,
Department of Clinical Oncology, Queen Mary
Hospital, 102 Pokfulam Road, Hong Kong SAR
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