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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5552_Библиотеки_им_академика_М_И_Перельмана
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74 Biomechanical Stimulation and its Clinical Prospects Nahum Rosenberg
Elastin 38
Embryonic stem cells 25
Endothelial cells 24, 55
Enhanced osteoblasts 68
Epidermal mitosis 38
Epidermis 37, 38, 39
Eukaryotic cells 3
Exposure of osteoblast cultures 16
External distraction force 65, 66
External mechanical force 8, 13, 23, 52
External mechanical stimulation 8, 9, 30
External mechanical stimuli 49
Extracellular matrix 4, 5, 9, 26, 35, 38, 39, 59, 60
F
Fibroblasts 13, 35, 39, 40, 41, 42, 43
Fibrous tissue 39
Fluid flow 5, 13, 14, 24, 51, 52, 55, 61
Fluid shear stress 5, 24, 25, 26
Focal adhesion kinase (FAK) 40, 41
Force propagation 3, 6, 7, 31
G
GAG chain length 61, 62
Gene expression 5, 9, 25, 26, 30, 31, 40, 62, 67
Generated bone tissue 66, 67, 70
Generating cells 8
Genetic expression 66, 68, 70
Glycoproteins 35, 36
Golgi apparatus 61
Golgi apparatus. glycosaminoglycans (GAG) 35, 59,
61
G protein-coupled receptors (GPCR) 43
Growth factors 26, 27, 31, 35, 49, 50, 51, 52, 54, 65,
66, 68, 69
H
HIF1α 70
Human osteoblasts in culture 55
Humoral factors 24, 51, 52, 68
Humoral growth factors 29, 30
Hydrostatic pressure 39, 61, 62
Hypertrophic scars (HS) 40, 42
I
Inflammatory cytokines 52, 54
Infrasonic range 13, 17
Integrins 14, 26, 39, 40, 41, 43, 51, 60, 61, 62
Intermediate filaments 3, 4, 51
Interstitial fluids 36
Intracellular calcium 43
L
Lining cells 49
M
Mammalian cells 40
MAPK pathways 40, 41, 42
MAPKs 41, 51
Marrow-derived stem cells 31
Matrix elaboration 9
Matrix material properties 27, 28
Matrix stiffness 24, 25, 26, 27
Matrix synthesis 61, 62
Maturation fate 29, 30
Mature cells 23
Mature osteoblasts 14, 69
Maximal strain 16
Mechanical stimulation by distraction 66
Mechanical stimulation modulation 67
Mechanical stimulation of fibroblasts 39
Mechanical stimuli 23, 24, 25, 39, 49, 51, 52, 61,
62
Mechanical strains 30, 41, 42, 52, 54
Mechanical stress 8, 25, 54, 59, 60, 61, 62
Mechanoreceptors 39, 51, 60
Mechanosensors 51
Mechanosignaling pathways 35, 39, 40
Mechanotransduction pathways 3, 5, 25, 68
Membranous distraction osteogenesis 65, 67
Mesenchymal cells 13
Mesenchymal derived cells 23
Mesenchymal origin 3, 9, 13
Mesenchymal progenitor cells 27
Mesenchymal stem cells (MSCs) 9, 13, 23, 24, 25,
27, 28, 29, 30, 31, 66, 67, 69
Metabolic response 13, 14
Methods for mechanical stimulation 13, 16
Microfilaments 13, 14, 51
Microtubules 3, 4, 51
Migrating cells 4
Mitosis 3, 4, 37, 53
Molecular signaling 35
mRNA 40, 53, 68
MSCs and embryonic stem cells 25
MS ion channels 39
Multipolar cells 14
Multipotent cells 24
Muscle stem cells 28
Myofibroblasts 38, 40, 43
Myosin II 4, 7
N
Neovascularization 65, 69, 70
Subject Index Biomechanical Stimulation and its Clinical Prospects 75
Nerve cells 49
Non-excitable cells 61
O
Osmolarity 61, 62
Osteoarthritis 61, 62
Osteoblast adherent 17
Osteoblast cultures 16
Osteoblastic differentiation 27
Osteoblastic expression 30
Osteoblastogenesis 54, 65
Osteoblastogenic events 52
Osteoblast responses 16
Osteoblasts 8, 13, 14, 15, 16, 17, 19, 21, 49, 50, 51,
52, 53, 54, 55, 56, 65, 66, 67, 68, 70
Osteoblasts act 8
Osteoblasts and osteocytes 8, 51
Osteoblasts apoptosis 55
Osteoblasts bullock Cell 21
Osteoblasts co-ordinate 49
Osteoblasts proliferation differentiation 52
Osteoblast stimulation 9
Osteocalcin 29, 51, 68, 69
Osteoclasts 49, 50, 66, 69
Osteocytes 8, 49, 51, 52, 55
Osteogenesis 28, 49, 50, 51, 55, 66, 67, 69, 70
Osteotomy 65, 66
Osterix 52
P
PGE2 51, 52, 54
Primary mineralizing front 68, 69
Progenitor cells 9, 65
Protein signalling 41, 42
Proteoglycans concentration 59, 60
R
Receptor tyrosine kinases (RTK) 43
Regenerating bone 69
S
Scaffold orientation 30
Signaling cascade 61
Signalling pathways 5, 42, 43, 51
Skin stretching 36, 37
Smooth muscle cells (SMCs) 24, 30
Somatic stem cells 25
Square osteoblasts chicks DNA 21
Stable osteoblastic phenotype 9
Stem cell differentiation 23, 31
Stem cells 23, 24, 25
Stem cells differentiation 25
Stimulate osteoblast proliferation 54
Stress relaxation 35, 36
Stretchable membranes 16
Stretched primary osteoblasts 54
Stretching membrane 13, 18
Structural properties 35
Subcutaneous fat 38, 39
Supporting matrix 27, 29
Supporting platform 18
Surface movement 18
Surface topography 24, 25, 29
T
Transcription factors 42, 50, 51, 62, 68, 70
Tumour necrosis factor (TNF) 42, 54
V
Vascular cells 24
Vascular endothelial cells 66
Vascularization 66, 67
Vascularization process 70
VEGF 51, 54, 69
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