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Muscle flap
8 Surgical Treatment ofAnal Fistula
147
Operating instructions: peel off the stula from the external opening all the way to the pri­mary abscess between the muscles. When there is no secondary stula, the skin between the anus and coccyx is incised longitudinally in the posterior midline and dissociated to its deepest parts. Since the deep lesions are located above the levator ani, below the sacrum, and in front of the coccyx, in order to thoroughly clean the pri­mary lesions, the coccyx should be removed after separation if necessary and reach the lesions behind the rectum from above the sphincter. The lesions in the pelvirectal fossa are gradually stripped from top to bottom, excised, and opened for drainage.
Then, the primary stula is stripped and excised from the inner opening. The inner open­ing is separated from the surrounding internal sphincter, and after clamping with a Cochle forceps, the stula in the internal sphincter is dis­sected until the primary abscess is stripped and removed. Then, suture the wound in the internal sphincter of the inner mouth, and make the drain­age wound of external drainage from the anus. Open drainage is performed on the wounds after stulectomy of the external orice and intermus­cular abscess or after resection of the coccyx of the sacral anterior rectum posterior (Fig.8.26).
Sometimes the stula leads to the left and right sides of the anococcygeal ligament, and
Cut Coccyx
Levator Ani M.
Fig. 8.26 Sphincter preservation operation for pelvic rectal fossa stula. Excavate the stula between the inter­nal opening and the primary abscess from the anus, and use the method to suture the internal and external active muscles and the levator ani muscles to close the wounds.
Digging and planing
Open drainage
Muscle flap tamponade
Suture atresia
Cut all pelvic and rectal fossa from the outer sphincter arc, and scrape or excise. If there is a large wound after treat­ing the stula in the pelvic rectal fossa, the gluteus maxi­mus ap can sometimes be used
filling
148
R. Shi and L. Zheng
sometimes it extends to the front of the sacrum. When handling such a stula, it is necessary to prevent missing branches. If the wound after excision of the primary abscess is too large, it will prolong the healing time. The gluteus maxi­mus can be used as a pedicled muscle ap to ll the wound. Because these deep anal stulas are likely to be associated with canceration and Crohn’s disease, it is necessary to send the stula removed for pathological examination.
Anal Fistula Muscle Flap Filling Surgery
This is mainly aimed at the treatment of high anal stula (especially open surgery) when there are large tissue defects and prolonged healing time, anal local blood circulation is poor, anal defor­mation is obvious, cavity cannot be completely closed, or there are other noticeable issues. The purpose of lling the tissue defect produced by the operation with the muscle ap is as follows: (1) lling the dead space; (2) using the blood sup­ply rich in the muscle ap, absorbing the secre­tion of the abscess and the necrotic tissue, and exerting the internal drainage effect, so that the dead space gradually disappears; and (3) using the muscle ap to block the trafc between the internal and external wounds so that the muscle ap acts as a barrier between the intestinal cavity and the lesion, preventing feces from contaminat­ing the wound and thus promoting healing. It is suitable for complex anal stula, high intermus­cular stula, ischiorectal fossa stula, and so on. The muscle ap lling method is recommended in Japan by Iwatari, Kono, and Takano.
Main operating points:
according to the position of the stula and the amount of excision of the diseased tissue.
(a) Type I (single muscle ap method)
The primary lesion is found by sepa­rating the muscle space, the abscess cav­ity is curetted sufciently, the granulation tissue and necrotic tissue are removed, and the scar and hard wall of the cavity are excised or trimmed to soften the local area (Fig.8.27). Care must be taken dur­ing the operation to protect the anal sphincter and mucous membrane as much as possible. When the stula surrounds the rectum and causes rectal stenosis, as long as the longitudinal stula is cut off, the rectal stenosis can be eliminated, and no stula needs to be completely removed. For the cavity formed between internal and external sphincter muscles during surgery, a segment of the subcutaneous of the external sphincter near the cavity can be separated to form a single pedicled muscle ap, and then the muscle ap can be inverted 180° from the outside to the inside to ll the cavity and xed to the internal sphincter with catgut suture (Fig.8.28).
(b) Type II (double muscle ap method)
In the same way as in the usual anal stulectomy, the external sphincter is cut and the lesion is cleaned. For the defect caused by the treatment of the lesion, the two ends of the subcutaneous of the exter­nal sphincter are cut, and each is made
1. Muscle ap lling surgery of Kazuo Kono Under general anesthesia and after disin-
fection, a small amount of skin is cut through the lateral skin of the external orice, the inci­sion is extended upward to the anorectal, and the diseased anal sinus and mucosa in the inner mouth are removed. The diseased tis­sues around the inner opening, including the anal recess adjacent to the inner opening, are also fully removed. The low wide upper nar­row drainage wound exposes the internal and external sphincter muscle. Then, different muscle ap lling methods are adopted
Fig. 8.27 An indication of the treatment of primary lesions with muscle ap lling
Cavity
Before After
ab
Cavity
Before After
ab
8 Surgical Treatment ofAnal Fistula
Internal anal sphincter
External anal Sphincter (Subcutaneous)
Fig. 8.28 Muscle ap lling operation type I. (a) Before. (b) After
149
Internal anal sphincter
External anal Sphincter (Subcutaneous)
Fig. 8.29 Muscle ap lling operation type II. (a) Before. (b) After
into a pedicled muscle ap, and then the muscle ap is pulled to the center to be lled in the defect, sutured, and xed on the internal sphincter (Fig.8.29).
(c) Type III
When the outer orice is far from the anus and adjacent to the lateral side of the external sphincter, it can scratch and peel off the stula from the outer opening and
remove the primary lesion until reaching the outer sphincter muscle. After the pri­mary abscess is cleaned, a part of the tis­sue of the subcutaneous of the adjacent external sphincter is separated to form a pedicled muscle ap, which is inserted into the cavity 180° outward (rear), sutured and xed on the subcutaneous tis­sue (Fig.8.30).
150
Before After
External anal Sphincter
Subcutaneous tissue
ab
Cavity
Before After
ab
Internal anal
sphincter
Cavity
Fig. 8.30 Muscle ap lling operation type III. (a) Before. (b) After
R. Shi and L. Zheng
External anal Sphincter (Subcutaneous)
Fig. 8.31 Muscle ap lling operation type IV. (a) Before. (b) After
(d) Type IV (wrapping method)
For cases where the stula is located in the middle of the external sphincter, after treating the primary lesion of the stula, the dead cavity appears in the middle of the external sphincter. The method is to cut the subcutaneous of the external sphincter around the cavity to form a muscle ap, take the cavity as the center, ll the muscle ap as if wrapping a par­cel, and x it in the dead cavity (Fig.8.31).
(e) Type V (using the gluteus maximus)
In cases where the lesion is too large, the cavity left after the treatment of the lesion is also large; or there is external sphincter atrophy; or after many operations in the anus, the scar is severe, especially in the subcutaneous of the external sphincter, there is a serious scar, and it is difcult to use the external sphincter subcutaneous to obtain a muscle ap. Therefore, a gluteus maximus muscle ap can be used.
Gluteus maximus
Before
ab
Absorbable thread continuous suture
Mucosal wound margin
8 Surgical Treatment ofAnal Fistula
151
Cut the scar rst and nd the lesion and then remove it. Then extend the anal margin incision, expose and separate a portion of the gluteus maximal muscle bundle on the left side, and make a pedicled muscle ap of sufcient length. Between the incision scars, the muscle ap is pulled and lled in the dead space that appears after the lesion is removed, sutured, and xed on the inter­nal sphincter (Fig.8.32). In the preparation of the gluteus maximus muscle ap, it is necessary to pay attention to the deep and upper part of the gluteus maximus muscle, which is rich in blood vessels and nerves. However, what is needed to make the mus­cle ap is the part of the muscle of the glu­teus maximus near the anus with a diameter of 2–3 cm. So there is no need to worry about damaging blood vessels and nerves.
After the pedicled muscle ap is xed in the cavity with the above methods, the wound becomes at. Next, the margin of the mucosal incision is xed to the inter­nal sphincter by continuous overlocking suture with catgut and cover most of the suture line of the muscle ap. Continuous suture of the easily bleeding submucosa is also a measure to prevent hemostasis. In order to prevent blood and uid accu­mulation in the residual cavity, drainage strips can be placed in the mouth outside the anal stula or the newly opened small incision for drainage (Fig.8.33).
Two to four days before the muscle ap lling operation, diet control and bowel preparation should be done. Antibiotics should be taken orally to pre­vent infection within 1–2 days before sur-
Internal anal sphincter
Cavity
After
Fig. 8.32 Muscle ap lling operation type V. (a) Before. (b) After
Fig. 8.33 The
completion of the muscle ap lling operation
Internal anal sphincter
Drainage tube
152
R. Shi and L. Zheng
gery. Antibiotics should be continued for 2 weeks after surgery to prevent infection and contribute to the survival of the trans­planted muscle aps. A slag-free diet is given 2–3 days after the operation, and opioid tincture or codeine phosphate is given orally for 1–2 days to control defe­cation. A bath or sitz bath can be taken 2–3 days after the operation to clean the wound surface.
The wound is usually healed about 2 months after the operation, the induration basically disappears, the scarring and deformation of the anus are very light, and the softness is maintained. Among the 168 patients with muscle ap lling performed by Kono, 11 patients had the following problems: there were four cases of recurrence (2.4%), of which three cases were cured by the second operation and one case was planned for a second operation. Residual abscess occurred in three cases (1.8%), all of which were cured by simple incision and drainage. One case (0.6%) had residual induration swelling and was cured by local injection of antibiotics. One patient (accounting for
0.6%) had partial necrosis of the muscle ap and was cured by removing the necrotic part of the muscle ap. Two cases (1.2%) had residual blood and were cured by cutting and clearing the blood. The survival rate of the muscle ap is very high, and there are no cases of com­plete failure due to incomplete lling and suture of the muscle ap, or the muscle ap came completely out of the dead space and must be removed. The preven­tion measures for the above problems are as follows: the pedicle of the pedicle mus­cle ap should be broad enough to main­tain adequate blood supply; a drainage strip should be placed between the mus­cle ap and the dead space for drainage 2–3 days after surgery.
2. Muscle ap lling surgery of Masahiro
Takano
This is suitable for the treatment of whole horseshoe-shaped anal stula with the inner mouth at the back.
Main operative points:
(a) Filling method I
The diseased tissue between the poste­rior inner port and the primary abscess is removed, and the drainage wound is made in the same way as the Hanley procedure. The muscle ap is used to ll the stula hole leading to the bilateral branches (Fig.8.34).
(b) Filling method II
Without cutting the sphincter, the dis­eased tissue between the internal opening and the primary abscess is removed from the anus and the defect is lled with a muscle ap (Fig.8.35). The subcutaneous portion of the external sphincter can be used for lling, but the subcutaneous por­tion of the external sphincter is thin and supercial, so it is not enough to use as a lling material, so it is better to use the supercial portion of the external sphinc­ter as the lling material.
Internal Sphincterotomy (Eisenhammer Method)
Eisenhammer put forward the theory of “inter­muscular stula abscess” in 1958. Based on this theory, for the treatment of intermuscular abscess
Fig. 8.34 Muscle ap lling of ischiorectal fossa stula
1. The internal mouth and the primary abscess were incised to make a drainage wound and open drainage. Fill the wound with a nearby muscle ap to prevent dirt from invading, and insert a drainage strip at the end of the s­tula to drain
8 Surgical Treatment ofAnal Fistula
153
Fig. 8.35 Muscle ap lling of ischiorectal fossa stula
2. The part between the internal mouth and the original abscess was stripped sneakily from the anus, and the mus-
and anal stula, he advocated the incision of anal crypt and intermuscular abscess from the anus and performed anal drainage without cutting the external sphincter but only cutting off part of the internal sphincter.
Operation points: open the anus with a two­lobe anoscope, expose the inner orice area, gently hook the inner opening position with the crypt hook, and cut the inner opening and the inner end of the stula under the guidance of a crypt hook. The length of the incision is
1.5–2cm, scratch the tissue, and trim the wound. When the posterior hoof-shaped stula is long, the incision is cut in the posterior middle inner mouth area, and then the incision is cut at a dis­tance of 1 cm in each of the two sides of the pipe. The subcutaneous tissue is separated and the stula is punctured, and a curette is inserted into the stula to scrape the anal incision and the distal end of the stula. The wound is open, and no drainage strips are placed.
Detachment Therapy (Insert Medicine Therapy)
This is one of the traditional Chinese medicine treatments. It is a corrosive drug wrapped with ne cotton paper, such as Hydrargyrum oxyda-
cle ap taken from the surrounding was transferred to the dead space to be sutured and closed
tum crudum, Hydrargyrum chloratum composi­tum, or Kuzhisan, and rubbed into a medicine twist. Or the above drugs plus appropriate excipients are used to make medicine sticks or medicine nails. The medicinal twist or medicine nail and the medicine stick are inserted into the stula tube to make the tube wall corrode and fall off, and the purpose of curing the anal s­tula is achieved.
The treatment of anal stula by the method of detachment therapy was rst recorded in the book “The Peaceful Holy Benevolence Formulae” in the Song Dynasty. It describes the method of treating the anal stula by dissolving arsenic in yellow wax and rubbing it into a sliver and putting it into the hemorrhoids’ tube. By the Ming and Qing dynasties, detachment therapy was widely used to treat anal stula. For exam­ple, in “Puji Fang” the paper twist of Danfan San (Chalcanthite, keel, huangdan, snake exuviate, musk) was put into wounds, and this was the ear­liest record of the medicine twist without arse­nic. “Wai Ke Qi Xuan” detailed the preparation method of the medicinal twist: rst probe the size and depth of the pipeline with a probe, and then apply the medicinal twist according to the condition of the pipeline, and the principle of
154
R. Shi and L. Zheng
later dressing change is adopted. The treatment of anal stula by “San pin yi tiao qiang” medici­nal strip created by “Orthodox Manual of External Diseases” had a great impact on later generations. The Qing Dynasty’s “Wai Ke Da Cheng” specially introduced the technical requirements and prognosis of inserting a medi­cine nail and the result of the misuse of oint­ments. According to the book, “do not insert the medicine into the bottom of the tube, such as a hole depth of one inch, the insertion depth is preferably 0.7–0.8 inches for the degree, insert it twice in the morning and evening, …. When it is observed that there is no carrion in the wound and its surroundings, switch to Shengji powder. When the pus is thick, use pearl to promote heal­ing. Do not stick the ointment for fear that it will drain and the wound will recover slowly.”
Commonly used drugs for the detachment therapy include Hong Sheng Dan and Bai Jiang Dan that are sold in pharmacies. No. 1 detach­ment nail, No. 2 detachment nail, and shengji nail are self-made, and these are all from the book “Treatment of Anorectal Surgical Diseases with Integrated Traditional Chinese and Western Medicine.”
The No. 1 detachment nail consists of Baijiangdan 6g, red powder 9g, cinnabar 4.5g, coptis 9g, raw gypsum 18g, toad venom 1.5g, and daemonorops draco 9 g. The medicine is mixed and ground into a ne powder and is added into 80% japonica rice and 20% rubber powder to make an adhesive agent. The ratio of the powder to the adhesive is 5:1. Mix it evenly to make a nail with a length of 1.5–5cm and as thick as a matchstick and make spares. It has the effect of eliminating necrotic tissues and promoting gran­ulation and is anti-inammatory and analgesic when used in anal stula treatment.
The No. 2 detachment nail consists of 3g of red powder, 3g of frankincense (roasted), 9g of myrrh (roasted), 3 g of realgar, 6 g of Cortex Phellodendri Chinensis, and 6g of Procaine. The production method is the same as that of the No. 1 detachment nail. After the detachment therapy, the tube wall falls off, and it can be used if there is dirt and necrotic tissue in the wound.
The Shengji nail consists of musk; ampelopsis japonica 3g each; pangolin 6g; catechu, Bletilla striata, and Angelica dahurica each 3g; cinnabar; and mercurous chloride and ivory 1.5g each. The production method is the same as that of the No. 1 detachment nail. It has anti-inammatory and analgesic effects and is used for promoting tissue regeneration for astringency. It is used in patients with anal stula wall already falling off, and the wound surface is clean without necrotic tissue after detachment therapy.
Detachment Nail Detachment Therapy
This is suitable for the treatment of low simple anal stula (straight stula) and complex anal stula.
Operating points: use a syringe with a thin plastic tube and ll it with hydrogen peroxide and saline and thoroughly ush the stula. Then, the detachable nail is inserted into the stula to make the whole stula lled with medicine nails. When inserting the nails, attention should be paid to making the detachable nails not exceed the inner opening so as to prevent drugs from corroding the surrounding of the inner opening and enlarging it. Cut off the excess medicine nails at the outer orice to make them ush out­side. After covering the sterile gauze, x them with adhesive tape to prevent the nails from coming out. The medicine nails should be replaced once a day, and the stula should be thoroughly ushed when the nails are changed so that the medicine can fully touch the tube wall. This operation is carried out until the ber granulation tissue of the stula wall is corroded and peeled off by the detachment nail (generally in 4–5 days). The signs of complete detachment of the stula wall are that (a) no more purulent secretions are owing out of the stula; (b) pain is obvious when inserting the nails; and (c) bleeding easily when touching the lumen.
Detachment Therapy withDetachment Nail andHardening Injection toSeal theInternal Orice (291 Hospital)
This is suitable for high anal stula and posterior horseshoe anal stula.
8 Surgical Treatment ofAnal Fistula
155
Operating method: this method is based on the detachment therapy and involves injecting hard­ener around the inner opening to promote the adhesion and closure of the inner opening and improve the curative effect of detachment therapy. First, the stula is detached with a detachment nail. After the brous granulation tissue is removed from the stula wall, the internal orice is closed. Closing method: when injecting Xiaozhiling liq­uid with a syringe, choose a ne needle, and inject two to three points around the inner mouth, inject
0.5ml of medicine at each point, and then put on Vaseline yarn. If one closure is unsuccessful, the second closure can be made. After closure of the internal orice, the stula is not completely healed. Shengji nails should be inserted at the internal ori­ce to promote the growth of fresh granulation, which takes about 4–5 days.
Notes: (a) For complicated anal stula or horseshoe stula, the proximal canal can be incised by retaining the anorectal ring (the inci­sion site is within the anal skin line). (b) The external opening should be enlarged to facilitate the insertion of nails. (c) Avoid inserting nails too deep to avoid corroding the inner mouth and causing inner mouth enlargement, thus affecting the sealing effect.
Detachment Therapy withMedicinal Twist andThen Suturing theInner Mouth (Aliated Hospital ofChengdu College ofTraditional Chinese Medicine)
This is an improved anal stula detachment ther­apy based on the traditional detachment method. After removing the primary lesion, the internal orice is sutured directly to prevent contamina­tion and infection of the wound by feces. Purulent scavenging drugs are used to remove the stula wall and necrotic tissue, reducing the possibility of recurrence, thus improving the cure rate and better protecting the anal function.
Operating points: carefully ascertain the posi­tion of the inner and outer ports, running pipe­line, etc. The anal canal is pulled open with an anal retractor to fully expose the inner orice. With the inner orice as the center, an oval inci­sion is made in the size of 1 × 1.5 cm. The
mucosa, submucosa, internal sphincter, and inter­nal and external sphincters are incised gradually. Open the primary lesion located in the intermus­cular tissue from the inside of the anal canal. The necrotic tissues in the primary lesions are scraped with a small curette. The infected anal sinuses, anal glands, anal ducts, and proliferated and thickened intermuscular tissues are removed and rinsed repeatedly with normal saline. Fissures in the internal sphincter are sutured intermittently with 0/3 intestinal suture to close the medial end of the stula. Then the upper mucosa of the medial wound is freed properly to form a pedi­cled mucosal ap. The mucosa ap is sutured with the anal skin below by 0/3 intestinal thread or No. 1 silk thread to seal and cover the inner orice wound. For the remaining stulas, a small curette is inserted into the stula to scrape the necrotic tissue in the stula lumen, with empha­sis on the main canal, large branches, and dead lumen. If there are several external holes, they shall be dealt with separately in the same way. If the proximal part of the superior sphincter stula (posterior horseshoe anal stula) is curved and difcult to scratch, it can be cut at the bend of the canal behind the anus and scratched in segments. Then, depending on the size and depth of the pipeline, select the appropriate Ke Long Ben Jiang Dan medicinal twist to insert into the pipe­line through the outer opening, leaving 0.5-cm­long drug twist at the outer end for easy removal when replacing, and pay attention to protecting the normal tissues around the outer opening to prevent them from being corroded by the Danyao. If the outer opening has been closed, it can be cut into a small hole and then have the medicine nail put into it with a ball-head probe, taking care not to cause a false path. If there is connective tissue hyperplasia around the outer orice, it can be cut by appropriate trimming or a small circular inci­sion along the outer edge. Finally, Vaseline yarns are placed in the anus to cover the wound surface of the inner mouth, and external tower-shaped yarns are applied and xed as pressure bandag­ing. A uid diet is administered for 2 days after the operation, stool control should last for 2–3 days, and antibiotics should be used appropri-
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ately. The dressing is changed once a day, and arnebia oil yarn is used for drainage in the anal canal. Change the Ke Long Ben Jiang Dan medicinal twist on the outside of the pipeline until the pus is removed and then stop using the twists. It usually takes 4–6 days for the twist to be used. Then change the Shengji powder or let it heal naturally.
Internal Orice Incision andPipeline Drainage withMedicated Thread (Li Yunong)
This is suitable for complex anal stula with mul­tiple external orices and curvature of the stula canal, accompanied by many branches, and the external mouth distance from the anal margin is above 5cm.
Operational essentials: under the local anes­thesia of the anal margin, the inltration anesthe­sia is performed with procaine or lidocaine containing a small amount of adrenaline around the stula. Dye the stula with methylene blue mixed with hydrogen peroxide. If the inner open­ing is in the posterior position, open the inner mouth, anal recess, and part of the anal internal anal sphincter, and open the deep postanal space. If the inner opening is elsewhere, only the inner mouth, anal recess, and part of the anal sphincter are incised. Use a soft probe with a round head to slowly penetrate from the outside orice, through the stained inner orice, and scratch stula with a curette. Scrape all the stained tube wall granula­tion, extract the probe, and lead the medicated line into the stula, loosely ligate both ends of the drug line, dry the gauze locally, then wrap it with an absorbent cotton pad, and x it with adhesive tape. Hot saline sitz bath is used after defecation after the operation. Change the medicated line one time on the second day after the operation, and withdraw the medicated line on the second day after indwelling. The incision is dressed daily with Jiuhua ointment gauze until the wound healed.
Ligation oftheIntersphincteric Fistula Tract (LIFT)
In 2007, Thai doctor Rojanasakul and others introduced a new type of sphincter preservation surgery, namely ligation of the intersphincteric
stula tract (LIFT), in the Thai Medical Association Journal. After the publication of the paper, it attracted the attention of the Center for Colorectal Surgery and Pelvic Floor Diseases at the University of Minnesota Hospital, and it con­ducted a multicenter study of LIFT surgery in the United States to promote this new technology. LIFT surgery has a high application value for mature low sphincter anal stula and mature and unbranched high sphincter anal stula. LIFT sur­gery is seen as a rst-line treatment and as impor­tant as stula incision and thread drawing.
Operation points: use spinal anesthesia or general anesthesia, take the prone folding knife position or lithotomy position. First, hydrogen peroxide is injected from the external opening of the anal stula to identify the internal opening, and then a probe is used to probe in from the external opening and pierce out from the internal opening, and this is used as a sign for the stula. An arc- shaped incision about 2–3 cm long is made along the outer edge of the internal and external sphincter groove. The combination of sharpness and bluntness separates the internal and external sphincter groove. Fully expose and free the brotic stula, and the stulas are clamped and ligated as close as possible to the inner orice (internal sphincter) of the intermus­cular stulas. Cut off the intermuscular stula and remove any excess remaining parts of the s­tula. Then, clamp, ligate, or suture the external opening of the intermuscular stula, and use the absorbable suture to close the defect of the exter­nal sphincter at the external opening of the inter­muscular stula. The external orice of the anal stula and the stula outside the sphincter are excavated down the tunnel, and the wounds are opened for drainage (Figs.8.36 and 8.37).
A systematic analysis of the study of LIFT surgery for anal stula by Yassin etal. showed that the success rate after summarizing the data was 71%. A total of 183 patients were evaluated for anal function, and 11 (6%) had mild anal incontinence. A randomized controlled trial with the repair of shift muscle ap showed no statisti­cal signicance in the difference of success rate between the two. After stratied analysis, the cure rate of LIFT surgery in high complex sphinc-