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Decoction and Their Biological Activities
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Decoction and Their Biological Activities
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Zhou, W., Cheng, X., & Zhang, Y. (2016). Effect of Liuwei Dihuang decoction, a traditional Chinese medicinal prescription, on the neuroendocrine immunomodulation network. Pharmacology & Therapeu- tics, 162, 170–178. Advance online publication. doi:10.1016/j.pharmthera.2016.02.004 PMID:26896567
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Chapter 3
Role of Medicinal Plants and
Herbs in Veterinary Medicine
Bhumika Varshney
Mangalayatan University, India
Sumit Malik
Shoolini University, India
Ajeet Singh
https://orcid.org/0000-0002-4393-8889
Gurukul Kangri University, India
Nikhil Mehta
Kurukshetra University, India
ABSTRACT
Ethnoveterinary medicine is a branch of ethnobotany concerned with the study of traditional remedies. Ethnoveterinary methods are as old as domestication of numerous livestock species when it comes to animal healthcare. Herbal medicine has experienced a variety of conceptual modifications over time, yet its tone has stayed mostly same from antiquity to the present. Antibacterial, antifungal, insecticidal, and antioxidant action has been demonstrated for plants. Herbal treatment strives to not only cure the underlying cause of the illness, but also to reverse aberrant symptoms and restore the animals’ health and vigour.
INTRODUCTION
Medicinal plants have been used as a source of healing in local communities all over the world for thousands of years. Nonetheless, for around 85 % of the world’s population, it is still significant as a primary healthcare technique, and as a drug discovery resource, with 80% of all synthetic medicines derived from them (Bauer & Brönstrup, 2014; Singh & Navneet, 2016, 2017a).It is unsurprising that people have utilised the same plant remedies for the animals in their care for as long as humans have been
DOI: 10.4018/978-1-6684-5129-8.ch003
Copyright © 2022, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited.
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Role of Medicinal Plants and Herbs in Veterinary Medicine
Figure 1. Administering liquid medicine with a bamboo bottle is an aspect of the old Chinese-Japanese art of horse healing.
linked with animals. Thus, for most of history, the evolution of veterinary botanical medicine, the earliest kind of veterinary medicine, has paralleled the progress of human medicine. Indeed, herbal medicine has experienced a lot of conceptual transformations throughout history, but its tone has remained sub­stantially unaltered from antiquity to the present. Herbal medicine is holistic, empiricist, and vitalist in attitude, and some herbalists believe that it should stay such even while contemporary medicine attempts to embrace the use of herbs as “drugs” in search of the “active ingredient.” This “scientism,” which may verge on reductionism, is essentially a new philosophy in the context of herbal medicine (Pešić, 2015).
Evidence shows that Ayurveda, which originated in India, was possibly the first medicinal system. The use of medicinal herbs in the treatment of people and animals is mentioned in the Rig Veda, the earliest source of human knowledge, written between 4500 and 1600 BCE. The “Nakul Samhita,” pub­lished about the same time, was possibly the first book on the use of herbs in the healing of animals. Animal husbandry chapters such as “Management and Feeding” may be found in ancient texts such as the Skandh Puran, Devi Puran, Harit, and others. Palkapya (1000 BC) and Shalihotra (2350 BC) were well-known veterinarians who specialised in elephant and horse care (Unknown, 2004). King Asoka (274-236 BC) commissioned individuals to cultivate herbs for use in the care of ill and elderly animals (Wynn & Fougère, 2006). Ricinius, pepper, lily, and valerian are among the medicines described in early Ayuvedic literature of the CharakaSamhita (200 BC-AD 200). Vasant Lad characterises the foundation of Ayurveda (“life science”) in a way that mirrors the Tao of Chinese medicine and the humours of Greek medicine:
In 3700 BC, a Chinese monarch called Shen Nong composed one of the earliest known and longest surviving Materia Medica. Shen Nong (the Divine Farmer) is regarded as the legendary founder of
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Role of Medicinal Plants and Herbs in Veterinary Medicine
Chinese herbal medicine. Hundreds of plants are said to have been tasted by him, identifying those that may be used as cures, and characterising their qualities. As a result of his work, several plants are now commonly utilised in treatment, and information has been passed down through oral tradition for genera­tions. His herbal Materia Medica book included herbal Materia Medica for both humans and animals. It’s worth noting that it talked about the antifever effects of Artemesia annua (Chinese wormwood), which has recently been proved to be particularly efficient against malaria (Yang, 1997).
When compared to the Egyptians, the ancient Greek and Roman societies advanced veterinary sci­ence in comparable but slightly distinct paths. The “Hippiatrika” is one of the first writings we come across that mentions Roman practitioners and their study of horses (Walker, 1991). Around 500 BC, the name “Hippiatros” was used in Greece to designate to horse physicians (Swabe, 1999). The horse was important in Greek and Roman civilization because members of society relied on it for military and commercial purposes. Earlier (between 383 BC and 322 BC), Aristotle, known as the “Father of Veteri­nary Medicine,” was a powerful figure in Greek culture. Aristotle’s publications covered a wide range of topics, including physiology, comparative anatomy, and disease.In works such as HistoriaAnimalium, De Partibus Animalium, De Generatione Animalium, and Problematicum, he contrasted animal and human anatomy, physiology, and illness (Zerobin, 1998). Hippocrates had a significant impact on both veterinary and herbal medicine (460-377 BC). He developed the humoral theory and authored Corpus Hippocraticum, in which he described over 200 plants.
Herbal medicine is being employed as a whole system of treatment by herbalists and as a supple­mentary therapy by medical experts. Regardless of how herbs fit into the practise of medicine, there is typically some guiding theory at work for their prescription. According to modern herbalists, there are three major principles that underpin herbal use: (i)scientific herbal medicine, or Phytotherapy—this is often reductionistic, researching herbs and illnesses in isolation in order to comprehend them as mo­lecular interactions that can be studied more easily than complete systems. Evidence-based therapies are commonly used by phytotherapists; (ii) Heroic—in this theory, disease is generally viewed as an accumulation of poisons that worsens with age. The treatment focuses on detoxification and limiting one’s exposure to pollutants. The herbs utilized in this tradition are potent, beginning with laxatives, diuretics, and diaphoretics (iii) Traditional medicine—The most comprehensive of the traditions. Wise Woman medicine, Native American medicine, Chinese medicine, and other cultural medical systems are examples of traditional medicine and views the organism, restoring health with basic herbs, physical exercise, diet, and mental support (Babu et al., 2017; Singh et al., 2017).
APPLICATIONS OF SELF-MEDICATION
Health-maintenance programmes are adaptable, but they are not without flaws. The capacity to properly self-medicate necessitates a complex combination of intrinsic behavioral skills and refinement gained via learning (experience). It is not proper to abandon sick animals, even if they are free roaming, in the expectation that they would find a method to self-medicate, especially naive or domesticated animals. The greater the number of opportunities for animals to understand the consequences of their behaviors, the better. Domestication has not chosen individuals based on their capacity to self-regulate, and the domestic setting frequently gives minimal chance for trial and error, exposure to potentially harmful bioactive compounds, or gaining knowledge through other people’s observations. Nonetheless, consider-
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Role of Medicinal Plants and Herbs in Veterinary Medicine
Figure 2. Chimpanzee sucks on the bitter pith of Vernoniaamygdalina (bitter leaf) in Tanzania. (Courtesy Michael Huffman)
ing the scarcity of studies in this field, the examples shown here show that domestic animals maintain a surprising breadth of self-medicating abilities.
Understanding how animals seek to self-medicate is critical if we are to create optimal self-regulation circumstances. Hedonic feedback can explain a lot of the self-medication we witness. This guarantees that animals rarely seek to eat very harmful chemicals and instead favor ones that provide immediate positive feedback. When it comes to finding relief from discomfort, hedonic feedback guarantees that animals employ safer, less potent “treatments” and only on rare occasions succumb to the harsher, fre­quently more poisonous medicines. This suggests that long-term moderate self-regulation will be more prevalent than spectacular therapeutic efforts including heavy drugs. Individuals are prone to intoxication and even addiction when they consume drugs that give a “feel good component.” Although not covered in this article, both intoxication and addiction occur in both wild and domestic species. The fact that an animal rapidly eats a drug does not imply that the substance is safe to take in infinite quantities.
Chimpanzees and humans have equivalent taste preferences. They favour sweet dishes to bitter ones. Vernonia amygdalina, often known as bitter leaf, is a tiny plant found in Tanzania’s Mahale Mountains. Most indigenous animals are effectively kept away by its intense bitterness, while introduced domesticated goats are unable to recognise the hazards; as a result, another frequent name for this plant is “goat killer.”
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Role of Medicinal Plants and Herbs in Veterinary Medicine
When ill, local chimps seek out this bitter, deadly plant, meticulously stripping off the outer layers of shoots and chewing and sucking the juicy bitter pith. Locals see the plant as a powerful remedy, using it to cure malarial fever, stomachaches, schistosomiasis, amoebic dysentery, and other intestinal parasites.
USES MEDICINAL PLANTS IN ZOONOTIC DISEASES
Gastrointestinal Disorders
The gastrointestinal system was the primary target of EVM, accounting for 28 % of total Ethnoveterinary therapy. The most commonly utilised species were Malvasylvestris L., Vitisvinifera L., and Matricari- achamomilla L. Apart from Mercurialisannua L., which has historically been employed as an anti-con- stipation agent, numerous plant species appear to be potential gastrointestinal agents (Vanderbrouckeet al., 2010). EVM herbs including wormwood (Artemisia absinthium L.), elderberry (Sambucusnigra L.), yarrow (Achilleamillefolium L.), and linseed (Linumusitatissimum L. seeds) may help with gastro- intestinal issues such colic, indigestion, tympani, and meteorism. On the one hand, they’re well-known in human phytotherapy for treating identical ailments (Mayer et al., 2014). Chewing willow by sheep enhances salivary output (Gieseckeet al., 1976), which might lead to rumination reactivation, according to EVM reports from Italy and Turkey. However, further pharmacological study is needed to back up these claims. The same may be said about garlic (Allium sativum L.), which is most widely used as an antiparasitic but has also been reported as a gastrointestinal agent by EVM in Italy. Garlic was recently studied in sheep to see whether it may help with digestion (Patraet al., 2011), however more fundamental research is needed to back up this claim. In terms of anti-diarrheal, EVM advocates a diverse range of plants, with no continuous repeat of the same species. Because of their tannin content, Quercus ilex L. and Hordeumvulgare L. may be beneficial (Favre et al., 1993), but more phytochemical understanding and standardised preparations are needed for clinical studies in ruminants.
Malvasylvestris L.
The principal components responsible for mallow’s medicinal benefits are mucilaginous heteropoly­saccharides, which are found mostly in the leaves (6.0-7.2 %), flowers (3,8-7,3 %), and roots (7,5 %). Leaves and aerial parts were usually provided orally and were thought to be beneficial in cases of numer­ous digestive disorders, such as abdominal colic, tympanism, reactivation of rumination in small and large ruminants, nonspecific digestive issues, diarrhoea, and constipation (Mayer et al., 2014; Singh & Navneet, 2017b).
Matricariachamomilla L.
A sesquiterpene-containing essential oil and flavones are the main components of chamomile flowers. Chamomile flowers and aerial parts were mostly used in EVM as a decoction or infusion to alleviate cattle digestion issues and colic discomfort. Scientific literature and veterinary phytotherapy textbooks and manuals (Wynn & Fougère, 2006; Mayer et al., 2014) support the usage.
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Role of Medicinal Plants and Herbs in Veterinary Medicine
Dermatological Disorders
Plant species that have been indicated for the treatment of dermatological problems, notably wound and ulcer preparations, may also could treat claw disorders.EVM lists three herbs that are effective against cow ringworm. Ilex aquifulium L. and Rhamnuscatharticus L. appear to have a more ceremonial function, but Lupinusalbus L. is the sole plant that may be applied directly to the skin. Although cow ringworm isn’t as common as human ringworm, it’s nonetheless a serious zoonotic fungal illness that need treatment (Havlickovaet al., 2008).In EVM (Full form), Broadleaf Plantain (Plantago major L.) was widely discussed as a vulnerary medicine. Veterinary phytotherapy books and manuals, as well as phytochemical investigations, appear to support its medical use. As a result, because there is presently little clinical research concerning veterinary usage, a specific veterinarian assessment would be required. Mallow and St. John’s wort (Hypericumperforatum L.), both well-known in EVM and listed as vulner­ary medications in scientific literature, are examples of this (Mayer et al., 2014). Although respiratory diseases are not a major problem in organic dairy farming, they are a major cause of antibiotic usage in conventional farms (Sivulaet al., 1996) and in other livestock species such as chickens and pigs. In EVM, the most common respiratory agents are mallow and chamomile. Antimicrobial characteristics may justify their usage, although more research into the impact on the respiratory system is needed. Inhaling chamomile oil has been shown to have positive effects in people (Salleret al., 1990). Given the particular toxicity of cardiac glycosides contained in the plants, the widespread usage of Helleborussp. in EVM comes as a surprise (Slifmanet al., 1998).Helleborus spp. roots or branches are put beneath the skin of ill animals in Italy, Romania, Serbia, and Turkey to cure respiratory disorders. Hellborus has been used as an immunostimulant (Nueleanu, 2008; Maior&Dobrotă, 2013).
Scrophulariacanina L.
This plant species has been used to heal dermatological issues, as well as cuts and ulcers, as well as claws and hoofs, according to EVM. Iridoid glycosides, a component of Scrophulariaceae, may have a function as active principle, however there is little published evidence (Stevenson et al., 2002; Tundiset al., 2014).
Pinushalepensis L.
According to contemporary study, the traditional usage of has a scientific basis, conifer resins for wound and ulcer therapy. The needles, twigs, and buds of the Aleppo pine have antibacterial action against a variety of bacterial diseases (Sipponenet al., 2008; Sipponenet al., 2012; Clark et al., 2014)
Antiparasitic Products
The cost of treating ruminants with anthelmintics in Europe is estimated to be over EUR 53 million per year (Ayazet al., 2008). The rise in drug resistance necessitates new approaches in both conventional and organic agriculture. Furthermore, gastrointestinal parasites pose a significant risk, particularly to organic sheep and goat production (Mayer et al., 2014).EVM identifies white lupin (Lupinusalbus L.) and cade (Juniperusoxicedrus L.) as the most potential anti-parasitic plants against ectoparasites. White lupin seeds are cooked and applied to the skin of animals, most likely owing to the alkaloid’s richness of the bitter variants of this plant (e.g., lupanin) (Wasilewko&Buraczewska, 1999), and are apparently useful
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