Use of the current edition of the electronic version of this book (eBook) is subject to the terms of the nontransferable, limited license granted on studentconsult.inkling.com. Access to the eBook is limited to the first individual who redeems the PIN, located on the inside cover of this book, at studentconsult. inkling.com and may not be transferred to another party by resale, lending, or other means.

2020_ME

Essentials of

Kumar & Clark’s

Clinical Medicine

ESSENTIALS

Series Editors

PROFESSOR DAME PARVEEN J KUMAR

CBE, BSC, MD, DM(HC), FRCP (L&E), FRCPATH,

Professor of Medicine and Education, Barts and The London School of Medicine and Dentistry, QMUL;

Honorary Consultant Physician and Gastroenterologist, Barts Health NHS Trust and Homerton University Hospital NHS Foundation Trust London, UK and

DR MICHAEL L CLARK

MD, FRCP,

Honorary Senior Lecturer, Barts and The London School of Medicine and Dentistry, QMUL, and Princess Grace Hospital, London, UK

Content Strategist: Alex Mortimer Content Development Specialist: Laurie Gower Project Manager: Andrew Riley Designer: Amy Buxton Illustration Manager: Teresa McBryan

ESSENTIALS OF

Kumar & Clark’s

Clinical Medicine

Seventh Edition

EDITED BY

NICOLA ZAMMITT

MBCHB, BSC(MED SCI), MD, FRCP(EDIN)

Consultant Physician and Honorary Clinical Senior Lecturer, Royal Infirmary of Edinburgh, Edinburgh, UK

EUAN A SANDILANDS

MBCHB, BSC(HONS), MD, FRCP(EDIN)

Consultant Physician and Honorary Clinical Senior Lecturer, Royal Infirmary of Edinburgh, Edinburgh, UK

Edinburgh London New York Oxford Philadelphia St Louis Sydney 2021

Elsevier

No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website:

www.elsevier.com/permissions.

This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

First edition 1995 Second edition 2000 Third edition 2003 Fourth edition 2007 Fifth edition 2012 Sixth edition 2018 Seventh edition 2022

ISBN 9780702082795 Int’l ISBN 9780702082801

British Library Cataloguing in Publication Data

A catalogue record for this book is available from the British Library

Library of Congress Cataloging in Publication Data

A catalog record for this book is available from the Library of Congress

Notices

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.

Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.

With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.

To the fullest extent of the law, neither the publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.

Printed in Scotland Last digit is the print number: 9 8 7 6 5 4 3 2 1

Preface vii Medical emergencies ix Abbreviations xiii Significant websites xxvii

1 Ethics and communication 1

2 Infectious diseases 12

3 Gastroenterology and nutrition 66

4 Liver, biliary tract and pancreatic disease 135

5 Haematological disease 193

6 Malignant disease 247

7 Rheumatology 267

8 Water, electrolytes and acid–base balance 320

9 Renal disease 345

10 Cardiovascular disease 398

11 Respiratory disease 491

12 Critical care medicine 553

13 Clinical pharmacology and toxicology 571

14 Endocrine disease 584

15 Diabetes mellitus and other disorders of metabolism 644

16 The special senses 677

17 Neurology 690

18 Dermatology 777

19 Elderly medicine and frailty 794

Normal values 817 Dictionary of terms 820 Index 831

This page intentionally left blank

Preface

Nicola Zammitt and Euan Sandilands

This is the seventh edition of Essentials of Kumar & Clark’s Clinical Medicine. This small medical textbook includes pathophysiology as the basis to understanding the clinical features and treatment for a range of disease processes. The book is based on its parent textbook, Kumar & Clark’s Clinical Medicine, from which we have taken these core principles. A key feature of the book is that its size makes it a convenient portable reference.

The sixth edition won the internal medicine category in the 2019 British Medical Association book awards. To build on that success, this seventh edition has been updated, in line with changes in clinical medicine and with its parent text. Both textbooks now include chapters on Medicine for the Elderly, to reflect the importance of an understanding of multi-disciplinary working, multi-morbidity and anticipatory care planning in modern medicine. The therapeutics sections at the end of each chapter have been updated to focus primarily on information relating to drug classes rather than individual drugs and their doses. It is beyond the scope of this book to provide an exhaustive drug list to cover prescribing in all patient groups. Finally, the evolving COVID-19 pandemic has rapidly changed the practice of medicine and our knowledge and understanding of this disease process is continually evolving. We have therefore chosen to focus on the principles of management and on sources of up to date information while avoiding describing fine details of management which may change in the coming months.

The current edition would never have evolved into the form you see today without Anne Ballinger, who edited the first five editions. Mike Clark and Parveen Kumar, the editors of Clinical Medicine, have offered support and assistance throughout all previous editions. However, Clinical Medicine is now under new editorial leadership and for this seventh edition, Essentials of Clinical Medicine also has a new editor; Dr Euan Sandilands. We believe that these changes have allowed us to produce an invigorated textbook and hope you find it a useful, user-friendly and enjoyable resource.

This page intentionally left blank

1 / 501 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 > Следующая >>>

Соседние файлы в папке Библиотека им академика М.И. Перельмана

#
02.09.202619 Мб0Книга_2818_Библиотеки_им_академика_М_И_Перельмана.pdf
#
05.09.202619 Мб1Книга_2821_Библиотеки_им_академика_М_И_Перельмана.pdf
#
05.09.202618 Мб0Книга_2822_Библиотеки_им_академика_М_И_Перельмана.pdf
#
05.09.202618 Мб0Книга_2823_Библиотеки_им_академика_М_И_Перельмана.pdf
#
05.09.202618 Мб0Книга_2824_Библиотеки_им_академика_М_И_Перельмана.pdf
#
09.09.202618 Мб0Книга_2826_Библиотеки_им_академика_М_И_Перельмана.pdf
#
09.09.202618 Мб0Книга_2831_Библиотеки_им_академика_М_И_Перельмана-1.pdf
#
09.09.202618 Мб0Книга_2831_Библиотеки_им_академика_М_И_Перельмана.pdf
#
31.08.202626 Мб0Книга_29_библиотеки_им_акад_М_И_Перельмана.pdf
#
31.08.202625 Мб0Книга_30_библиотеки_им_акад_М_И_Перельмана.pdf
#
31.08.202624 Мб0Книга_31_библиотеки_им_акад_М_И_Перельмана.pdf

Contents

Preface