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316 Substance Use in Older Adults
RESOURCES FOR CLINICIANS
American Psychiatric Association
Best Practice Highlights for Treating Diverse Patient Populations
(www.psychiatry.org/psychiatrists/diversity/education/bestpractice-highlights): These web pages and videos provide clinicians
information on w
(e.g., African American/Black patients, Muslim patients, indigenous patients), including addressing stigma and disparities.
Lewis-Fernández R, Aggarwal NK, Hinton L, et al: DSM-5
book on the Cultural Formulation Interview. Washington, DC, American Psychiatric Publishing, 2016: This book helps clinicians learn
to use the
1 and Case Example 11–1.
Cultural Formulation Interview, referenced in Table 11–
American Medical Association
Creating an LGBTQ-Friendly Practice: This Web page provides cli-
nicians with practical tips for creating an environment that is welcoming of LGBTQ patients (www.ama-assn.org/delivering-care/
creating-LGBTQ-friendly-practice).
orking with patients of various backgrounds
®
Hand-
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INDEX
Page numbers printed in boldface type refer to tables and boxes.
5 A’s tool, 167, 168, 177
5 R’s, 170, 171
12-step programs, 67, 79, 140, 146–
148, 192, 254–256
42 CFR Part 2, 64–65
AA (Alcoholics Anonymous), 67,
131, 140, 146–148, 298–299
ABCs of substance use, 66
Acamprosate, 141, 142, 262
Acetaldehyde, 129, 142
Activities of daily living (ADLs), 36,
310
Acupuncture, 231
Addiction
nicotine, 169
opioid, 198–199
stages, 5–6, 15
stimulant, 254
terminology, 2, 16
Addiction stages, 5–6, 15
binge/intoxication, 6
preoccupation/anticipation, 6
withdrawal/negative affect, 6
ADHD, 112–113, 260
Adverse childhood experiences
(ACEs), 8, 15, 72
Ageism, 2, 4, 15–16, 27, 28
Agency for Healthcare Research and
Quality, 100
Aging, physiological changes related
to, 38, 87–88, 89–90, 129–130
Agitation
antipsychotics for, 113, 252
, 116
benzodiazepines, 102
cannabis, 280, 282
cocaine, 246–247
in intoxication, 62
methamphetamine,
withdrawal, 165, 223, 312
Al-Anon, 149, 265
Alcohol, Smoking, and Substance
Involvement Screening Test
(ASSIST), 32, 225
Alcohol dehydrogenase genes, 7
Alcohol use, 125–150
at-risk drinking, 137
binge drinking, 10, 40, 61, 70, 127,
129, 137, 147
cannabis use with, 276
cardiovascular disease, 133
clinical symptoms and signs,
130–131
cognition, 133
comorbidities, 13
dementia risk, 14
detoxification, 63, 138–139, 142,
144
effects on older adults, 129–133
epidemiology, 128–129
hazardous/problem drinking,
127
heavy drinking, 126–128, 132–
133, 140, 143, 146, 262
introduction, 126–128
laboratory investigations, 37
medication interactions, 40
metabolism, 129–130
252
323

324 Substance Use in Older Adults
Alcohol use (continued)
moderate alcohol consumption,
127–128, 133
opioid use comorbidity, 194
overview of interventions, 59
physiological changes with
aging, 129–130
recommendations for safe use,
127–128
standard drink, 126, 127
terminology, 126–128
use among older adults, 126
withdrawal, 63, 132, 134, 139, 143
Alcohol use disorder (AUD)
assessment, 135–138
challenges, 137–138
comprehensive evaluation,
135–136, 136
screening, 136–137
benzodiazepine use, 112
case example, 130–131
clinical symptoms and signs,
130–131
comorbidities, 131–132
definition, 133
diagnostic criteria, 133–134, 134–
135
epidemiology, 10, 129
management, 138–147
detoxification, 139
key characteristics of age-sen-
sitive, 138
overview, 138
pharmacotherapy, 139–144, 141
psychosocial interventions,
144–147
mutual-help groups, 67
pharmacotherapy, 139–144, 141
acamprosate, 141, 142
baclofen, 141, 144
disulfiram, 141, 142–143
gabapentin, 141, 143
naltrexone, 140, 141, 142
overview, 139–140
topiramate, 141, 143
psychosocial interventions, 144–
147
brief interventions, 144–145
cognitive-behavioral therapy
(CBT), 145
motivational interviewing,
145
mutual-help groups, 146
in patient treatment, 144
virtual interventions, 146–147
resources, 148–150
SBIRT (screening, brief
intervention, and referral to
treatment),
Alcohol Use Disorders Identification
Test (AUDIT), 31
Alcohol withdrawal syndrome
(AWS), 63, 139, 143
Alcoholics Anonymous (AA), 67,
131, 140, 146–148, 298–299
Alprazolam, 103, 112
in case examples, 193, 223–224
misuse, 99, 215
Alzheimer’s disease, 114, 133, 165,
219, 249
American Association of Geriatric
Psychiatry, 315
American Medical Association, 316
American Psychiatric Association,
316
Position Statement on Substance Use
Disorders in Older Adults, 5
on tobacco use disorder, 178
American Society of Addiction
Medicine (ASAM), 64, 169, 234,
253
Amnesia, 43, 132, 219
Amphetamine, 241, 243–245, 249,
252, 255, 257–260
See also
Methamphetamine;
Stimulant use disorder
Amphetamine salts, mixed, 260
Amphetamine use disorder, 243, 255,
257
See also Methamphetamine use
order
dis
Anticholinergic medications, 39, 97,
106, 113, 223
144–145
, 32, 137

Index 325
Anticonvulsants
cocaine use disorder, 260–261
methamphetamine use disorder,
257
Antidepressants
cocaine use disorder, 258–259
methamphetamine use disorder,
256–257
polypharmacy, 106
tobacco cessation, 174
Antipsychotics
cocaine use disorder, 259–260
deprescribing, 113–114
methamphetamine use disorder,
257
Anxiety
benzodiazepines for, 217
case example, 223–224
complemetary and alternative
medicine, 176
safely addressing, 98
screening for snubstance use
comorbidity, 41, 42
Anxiolytics, for cocaine use disorder,
261
Aripiprazole, 257
Assessment, 25–51
alcohol use disorder, 135–138
background, 26–27
barriers to SUD identification,
27–30, 28–29
cannabis use, 285–287, 286, 288
comorbidities, 38–43, 42
comprehensive clinical
assessment, 34–37, 38
cultural, 296–300, 313–314
definition, 26
discussing substance use, 30–31
functional, 36
opioid use disorder, 196–197
sedative, hypnotic, or anxiolytic
use disorder, 225–226
step-by-step approach, 49
stimulant use disorder, 249–252,
253
suicide risk assessment, 43–46,
44–45
tobacco use, 165–168, 165–169
tools for safely prescribing
medications, 88
ASSIST, 32, 225
ASSIST-Lite, 225
Atomoxetine, 261
At-risk use, 2, 56, 58, 276
AUD. See Alcohol use disorder
AUDIT-C, 31, 32, 137
Autonomy, 305–306
AWS (alcohol withdrawal
syndrome), 63, 139, 143
Baclofen
for alcohol use disorder, 141
for cocaine use disorder, 261
for methamphetamine use
der, 257
disor
Barriers to care, 56–57, 68, 303
attitudes and social norms, 303
comorbid SUDs and psychiatric
disorders, 68
stigma, 57, 68, 226
Barriers to SUD identification, 27–30,
28–29
Beers Criteria, 39, 88, 91, 97, 218, 231
Behavioral and psychological
symptoms of dementia (BPSD),
280
Benzodiazepines
alcohol use with, 128, 139
complications in older adults,
218–219
coprescription of opioids, 103–
104, 216, 226
dementia risk, 14
deprescribing, 108–109, 111–112
detoxification, 63, 228
epidemiology, 214–216
indications in older adults, 216–
218
long-acting, 98
misuse, 215–216
, 144
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