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316 Substance Use in Older Adults
RESOURCES FOR CLINICIANS
American Psychiatric Association
Best Practice Highlights for Treating Diverse Patient Populations
(www.psychiatry.org/psychiatrists/diversity/education/best­practice-highlights): These web pages and videos provide clinicians information on w (e.g., African American/Black patients, Muslim patients, indige­nous patients), including addressing stigma and disparities.
Lewis-Fernández R, Aggarwal NK, Hinton L, et al: DSM-5
book on the Cultural Formulation Interview. Washington, DC, Amer­ican Psychiatric Publishing, 2016: This book helps clinicians learn to use the 1 and Case Example 11–1.
Cultural Formulation Interview, referenced in Table 11–
American Medical Association
Creating an LGBTQ-Friendly Practice: This Web page provides cli-
nicians with practical tips for creating an environment that is wel­coming of LGBTQ patients (www.ama-assn.org/delivering-care/ creating-LGBTQ-friendly-practice).
orking with patients of various backgrounds
®
Hand-
REFERENCES
Agner J: Moving from cultural competence to cultural humility in occupational
therapy: a paradigm shift. Am J Occup Ther 74(4):p1, p7, 2020 32602456
American Psychiatric Association: Diagnostic and Statistical Manual of Mental
Disorders, 5th Edition. Arlington, VA, American Psychiatric Association, 2013a
American Psychiatric Association: Older adults, in Supplementary Modules to
the Core Cultural Formulation Interview (CFI). Arlington, VA, American Psychiatric Association, 2013b
Anderson GO, Thayer CE: Loneliness and social connections: a national survey
of adults 45 and older
Buchman DZ, Russell BJ: Addictions, autonomy and so much more: a reply to
Caplan. Addiction 104(6):1053–1054, author reply 1054–1055, 2009 19466928
Burke AC, Gregoire TK: Substance abuse treatment outcomes for coerced and
noncoerced clients. Health Soc Work 32(1):7–15, 2007 17432737
Caplan A: Denying autonomy in order to create it: the paradox of forcing treat-
ment upon addicts. Addiction 103(12):1919–1921, 2008 19469727
. AARP Research, September 2018
Cultural, Structural, and Ethical Considerations 317
Cavaiola AA, Dolan D: Considerations in civil commitment of individuals with
substance use disorders. Subst Abus 37(1):181–187, 2016 25832824
Centers for Disease Control and Prevention: Cultural Competence in Health
and Human Se Prevention, 2021. Available at: https://npin.cdc.gov/pages/cultural­competence#what. Accessed February 28, 2023.
Chettiar IM, Bunting W, Schotter G: At America’s Expense: The Mass Incarcer-
ation of the Elderly. New York, American Civil Liberties Union, June 2012
Coviello DM, Zanis DA, Wesnoski SA, et al: Does mandating offenders to treat-
ment improve completion rates? J Subst Abuse Treat 44(4):417–425, 2013 23192219
Christopher PP, Anderson B, Stein MD: Civil commitment experiences among
opioid users. Drug
Cudjoe TKM, Roth DL, Szanton SL, et al: The epidemiology of social isolation:
National Health and Aging Trends Study. J Gerontol B Psychol Sci Soc Sci 75(1):107–113, 2020 29590462
Dasgupta N, Beletsky L, Ciccarone D: Opioid crisis: no easy fix to its social and
economic determinants. Am
Dineen KK: Disability discrimination against people with substance use disor-
ders by postacute care nursing facilities: it is time to stop tolerating civil rights violations. J
Donovan NJ, Blazer D: Social isolation and loneliness in older adults: review
and comme 28(12):1233–1244, 2020 32919873
Eisen JC: Civil commitment for substance abuse. Virtual Mentor 15(10):844–849,
2013 24152775
Evans EA, Harrington C, Roose R, et al: Perceived benefits and harms of invol-
untary civil commitment for opioid use disorder. J Law Med Ethics 48(4):718–
Federal Bureau of Prisons: Inmate age, in Inmate Statistics. Washington, DC,
Federal Bureau of Prisons, 2022. Available at: https://www.bop.gov/ about/statistics/statistics_inmate_age.jsp. Accessed December 19, 2022.
Goedel WC, Shapiro A, Cerdá M, et al: Association of racial/ethnic segregation
with treatment capacity for opioid use disorder in counties in the United States. JAMA Netw Open 3(4):e203711, 2020 32320038
Guerrero EG, Campos M, Urada D, Yang JC: Do cultural and linguistic compe-
tence matter in Latinos’ completion of mandated substance abuse treat­ment? Subst Abuse Treat Prev Policy 7:34–40, 2012 22898100
Guerrero EG, Khachikian T, Kim T, et al: Spanish language proficiency among
providers and Latino clients’ engagement in substance abuse treatment. Addict Behav 38(12):2893–2897, 2013a 24045032
Guerrero EG, Marsh JC, Duan L, et al: Disparities in completion of substance
abuse treatment between and within racial and ethnic groups. Health Serv Res 48(4):1450–1467, 2013b 23350871
Guerrero EG, Marsh JC, Khachikian T, et al: Disparities in Latino substance use,
service use, and treatment: implications for culturally and evidence-based interventions under health care reform. Drug Alcohol Depend 133(3):805– 813, 2013c 23953657
rvices. Atlanta, GA, Centers for Disease Control and
Alcohol Depend 193:137–141, 2018 30384320
J Public Health 108(2):182–186, 2018 29267060
Addict Med 15(1):18–19, 2021 32675799
ntary of a National Academies report. Am J Geriatr Psychiatry
734, 2020 33404337
318 Substance Use in Older Adults
Guerrero EG, Amaro H, Khachikian T, et al: A bifurcated opioid treatment sys-
tem and widening insidious disparities. Addict Behav 130:107296, 2022 35255242
Hansen H, Roberts SK: Two tiers of biomedicalization: methadone, buprenor-
phin on Addiction, Vol 14. Edited by Netherland J. Bingley, UK, Emerald Pub­lishing Limited, 2012, pp 79–102
Hargons CN, Miller-Roenigk BD, Malone NJ, et al: “Can we get a Black rehabil-
itation center”? Factors impacting the treatment experiences of Black peo­ple who use opioids. J Subst Abuse Treat 142:108805, 2022 35717365
Heyman GM, McVicar N, Brownell H: Evidence that social-economic factors
play an important r 284, 2019 31471008
Hollander MAG, Chang CCH, Douaihy AB, et al: Racial inequity in medication
treatment for opioid use disor riers to use. Drug Alcohol Depend 227:108927, 2021 34358766
Huhn AS, Strain EC, Tompkins DA, Dunn KE: A hidden aspect of the U.S. opi-
oid crisis: rise in first-time treatment admissions for older adults with opi­oid use disorder. Drug Alcohol Depend 193:142–147, 2018 30384321
Irwin P, Murray S, Bilinski A, et al: Alcohol withdrawal as an underrated cause
of agita malignancy. J Pain Symptom Manage 29(1):104–108, 2005 15652444
Jail and Prison Opioid Project: Facts and Resources. Providence, RI, Center
for He prisonopioidproject.org. Accessed May 31, 2022.
Jain A, Christopher P, Appelbaum PS: Civil commitment for opioid and other
subs 29607774
Jordan A, Mathis M, Haeny A, et al: An evaluation of opioid use in Black com-
munities: a rapid review of the literature. Harv Rev Psychiatry 29(2):108– 130, 2021 33666395
Kerrison E: An historical review of racial bias in prison-based substance abuse
treatment de
Kimmel SD, Rosenmoss S, Bearnot B, et al: Rejection of patients with opioid use
disorder referred for post-acute medical care before and after an anti­discrimination settlement in Massachusetts. J Addict Med 15(1):20–26, 2021 32675798
Kimmel SD, Rosenmoss S, Bearnot B, et al: Northeast postacute medical facili-
ties disproportionately reject referrals for patients with opioid use disor­der. Health Aff (Millwood) 41(3):434–444, 2022 35254930
Klag S, O’Callaghan F, Creed P: The use of legal coercion in the treatment of
substance abusers: an overview and critical analysis of thirty years of re­search. Subst Use Misuse 40(12):1777–1795, 2005 16419556
Krawczyk N, Picher CE, Feder KA, Saloner B: Only one in twenty justice-re-
ferred adults in specialty treatment for opioid use receive methadone or buprenorphine. Health Aff (Millwood) 36(12):2046–2053, 2017 29200340
Krinsky CS, Lathrop SL, Brown P, Nolte KB: Drugs, detention, and death: a
study of the mortality of recently released prisoners. Am J Forensic Med Pathol 30(1):6–9, 2009 19237844
e, and the racial politics of addiction treatment, in Critical Perspectives
ole in drug overdose deaths. Int J Drug Policy 74:274–
der: exploring potential facilitators and bar-
ted delirium and terminal restlessness in patients with advanced
alth and Justice Transformation, 2021. Available at: https://
tance use disorders: does it work? Psychiatr Serv 69(4):374–376, 2018
sign. J Offender Rehabil 56:1–26, 2017
Cultural, Structural, and Ethical Considerations 319
Lappan SN, Brown AW, Hendricks PS: Dropout rates of in-person
psychosocial substance use disorder treatments: a systematic review and meta-analysis. Addiction 115(2):201–217, 2020 31454123
Lekas HM, Pahl K, Fuller Lewis C: Rethinking cultural competence: shifting to
cultural 33424230
Lewis-Fernández R, Aggarwal NK, Bäärnhielm S, et al: Culture and psychiatric
evaluation: operationalizing cultural formulation for DSM-5. 77(2):130–154, 2014 24865197
Luallen J, Kling R: A method for analyzing changing prison populations: ex-
plaining the growth of the elderly in prison. Eval Rev 38(6):459–486, 2014 25015260
McLean K: “There’s nothing here”: deindustrialization as risk environment for
overdose. Int
Mennis J, Stahler GJ: Racial and ethnic disparities in outpatient substance use
disorder treatment episode completion for different substances. J Subst Abuse Treat 63:25–33, 2016 26818489
Mennis J, Stahler GJ, El Magd SA, Baron DA: How long does it take to complete
outpatient substance use disor Hispanics, and Whites in the US. Addict Behav 93:158–165, 2019 30711669
Merlin JS, Young SR, Arnold R, et al: Managing opioids, including misuse and
addi qualitative study. Am J Hosp Palliat Care 37(7):507–513, 2020 31763926
Metzl JM, Hansen H: Structural competency: theorizing a new medical engage-
ment with stigma and inequality. Soc Sci Med 103:126–133, 2014 24507917
Miller W, Rollnick S: Motivational Interviewing: Helping People Change, 3rd
Edition (Applications of Motivational Interviewing). New York, Guilford Press, 2012
Moyo P, Eliot M, Shah A, et al: Discharge locations after hospitalizations involv-
ing opioid use disorder among Medicare beneficiaries. Addict Sci Clin Pract 17(1):57, 202
Mutchler J, Li Y, Roldán NV: Living Below the Line: Economic Insecurity and
Olde and Demographic Research on Aging Publications, 2019. Available at: https://scholarworks.umb.edu/demographyofaging/40. Accessed May 28, 2023.
National Academies of Sciences, Engineering, and Medicine: Medications for
Op Press, 2019
National Institute on Drug Abuse: Criminal Justice DrugFacts. Bethesda, MD,
Nation nida.nih.gov/publications/drugfacts/criminal-justice. Accessed Decem­ber 19, 2022.
Nussbaum AM: Held against our wills: reimagining involuntary commitment.
Health Aff (Millwood) 39(5):898–901, 2020 32364875
Pagano A: Barriers to drug abuse treatment for Latino migrants: treatment pro-
viders’ perspectives. J Ethn Subst Abuse 13(3):273–287, 2014 25176120
Patallo BJ: The multicultural guidelines in practice: cultural humility in clinical
training and supervision. Train Educ Prof Psychol 13(3):227–232, 2019
humility. Health Serv Insights 13:1178632920970580, 2020
Psychiatry
J Drug Policy 29:19–26, 2016 26868674
der treatment? Disparities among Blacks,
ction, in patients with serious illness in ambulatory palliative care: a
2 36209151
r Americans, Insecurity in the States. Boston, MA, Center for Social
ioid Use Disorder Save Lives. Washington, DC, National Academies
al Institute on Drug Abuse, 2020. Available at: https://
320 Substance Use in Older Adults
Pew Charitable Trusts: Prison population continues to age. Pew Charitable
Trusts, October 3, 2014. Available at: http://www.pewtrusts.org/en/ about/news-room/news/2014/10/03/prison-population-continues-to­age. Accessed February 28, 2023.
Pinedo M, Zemore S, Rogers S: Understanding barriers to specialty substance
abuse tr
Porter LC, Bushway SD, Tsao HS, Smith HL: How the U.S. prison boom has
changed the age distribution of the prison population. Criminology 54(1):30–55, 2016 28936228
Prescription Drug Abuse Policy System: Involuntary Commitment for Sub-
stance Use. Philadelphia, PA, Center for Public Health Law Research, Te commitment-for-substance-users-1562936854. Accessed December 18,
2022.
Rising J, Whaley S, Saloner B: How the Drug Enforcement Administration Can
Improve Access to Methadone in Correctional Facilities and Save Lives. Baltimore, MD, Johns Hopkins Bloomberg School of Public Health, 2022
Roberts LW, Dyer AR: Concise Guide to Ethics in Mental Health Care. Washing-
ton, DC, American Psychiatric Publishing, 2004
Rosenberg A, Heimer R, Keene DE, et al: Drug treatment accessed through the
criminal justice system: participants’ perspectives and uses. J Urban Health 96(3):390–399, 2019 30191511
Rothrauff TC, Abraham AJ, Bride BE, Roman PM: Substance abuse treatment
for older adults
Schmidt LA, Ye Y, Greenfield TK, Bond J: Ethnic disparities in clinical severity
and services for vey. Alcohol Clin Exp Res 31(1):48–56, 2007 17207101
Schuler MS, Dick AW, Stein BD: Growing racial/ethnic disparities in buprenor-
phine distribution in the United State 223:108710, 2021 33873027
Section 35 Commission: Section 35 Commission Report. Boston, MA, Section 35
Commission, 2019. Available at: https://www.mass.gov/doc/section-35­commission-report-7-1-2019/download. Accessed January 15, 2024.
Skarupski KA, Gross A, Schrack JA, et al: The health of America’s aging prison
population. Epidemiol Rev 40(1):157–165, 2018 29584869
Stahler GJ, Mennis J: Treatment outcome disparities for opioid users: are there
racial and ethnic differences in treatment completion across large US met­ropolitan areas? Drug Alcohol Depend 190:170–178, 2018 30041092
Stahler GJ, Mennis J, Baron DA: Racial/ethnic disparities in the use of medica-
tions for opioid use disorder (MOUD) and their effects on residential drug treatment 34198132
Substance Abuse and Mental Health Services Administration: The Opioid Cri-
sis and the Black/African American Population: An Urgent Issue (Publ No PEP20-05-02-001). Rockville, MD, SAMHSA, 2020
Sue S, Fujino DC, Hu LT, et al: Community mental health services for ethnic mi-
nority groups: a test of the cultural responsiveness hypothesis. J Consult Clin Psychol 59(4):533–540, 1991 1918557
eatment among Latinos. J Subst Abuse Treat 94:1–8, 2018 30243409
mple University, 2021. Available at: https://pdaps.org/datasets/civil-
in private centers. Subst Abus 32(1):7–15, 2011 21302179
alcohol problems: results from the National Alcohol Sur-
s, 2007–2017. Drug Alcohol Depend
outcomes in the US. Drug Alcohol Depend 226:108849, 2021
Cultural, Structural, and Ethical Considerations 321
Tervalon M, Murray-García J: Cultural humility versus cultural competence: a
critical distinction in defining physician training outcomes in multicultural education. J Health Care Poor Underserved 9(2):117–125, 1998 10073197
van Draanen J, Tsang C, Mitra S, et al: Socioeconomic marginalization and opi-
oid-related overdose: a systematic review. Drug Alcohol Depend 214:108127, 2020 32650191
van Draanen J, Jamula R, Karamouzian M, et al: Pathways connecting socioeco-
nomic marginalization and overdose: a qualitative narrative synthesis. Int J Drug Po
Vargas Bustamante A, Fang H, Garza J, et al: Variations in healthcare access and
utilization among Mexican immigrants: the role of documentation status. J Immigr Minor Health 14(1):146–155, 2012 20972853
Verissimo ADO, Grella CE: Influence of gender and race/ethnicity on perceived
barriers to help-seeking 75:54–61, 2017 28237055
Wakeman SE, Rich JD: Barriers to post-acute care for patients on opioid agonist
therapy: an exam Med 32(1):17–19, 2017 27393486
Walaszek A: Behavioral and Psychological Symptoms of Dementia. Washing-
ton, DC, American Psychiatric Association Publishing, 2019
Walt G, Porteny T, McGregor AJ, Ladin K: Clinician’s experiences with involun-
tary commitment for substance use disorder: a qualitative study of moral distre
Werb D, Kamarulzaman A, Meacham MC, et al: The effectiveness of compul-
sory drug treatment: a systematic review. Int J Drug Policy 28:1–9, 2016 26790691
World Health Organization: Social Determinants of Health. Geneva, World
Health Organization, 2023. Available at: https://www.who.int/health­topics/social-determinants-of-health#tab=tab_1. Accessed March 31, 2023.
Wu L-T, Zhu H, Swartz MS: Treatment utilization among persons with opioid
use disorder in the United States. Drug Alcohol Depend 169:117–127, 2016 27810654
Zoorob MJ, Salemi JL: Bowling alone, dying together: the role of social capital
in mitigating the drug overdose epidemic in the United States. Drug Alco­hol Depend 173:1–9, 2017 28182980
licy 113:103971, 2023 36822011
ple of systematic stigmatization of addiction. J Gen Intern
ss. Int J Drug Policy 99:103465, 2022 34619444
for alcohol or drug problems. J Subst Abuse Treat

INDEX

Page numbers printed in boldface type refer to tables and boxes.
5 A’s tool, 167, 168, 177 5 R’s, 170, 171 12-step programs, 67, 79, 140, 146–
148, 192, 254–256
42 CFR Part 2, 64–65
AA (Alcoholics Anonymous), 67,
131, 140, 146–148, 298–299 ABCs of substance use, 66 Acamprosate, 141, 142, 262 Acetaldehyde, 129, 142 Activities of daily living (ADLs), 36,
310 Acupuncture, 231 Addiction
nicotine, 169 opioid, 198–199 stages, 5–6, 15 stimulant, 254 terminology, 2, 16
Addiction stages, 5–6, 15
binge/intoxication, 6 preoccupation/anticipation, 6
withdrawal/negative affect, 6 ADHD, 112–113, 260 Adverse childhood experiences
(ACEs), 8, 15, 72 Ageism, 2, 4, 15–16, 27, 28 Agency for Healthcare Research and
Quality, 100 Aging, physiological changes related
to, 38, 87–88, 89–90, 129–130 Agitation
antipsychotics for, 113, 252
, 116
benzodiazepines, 102 cannabis, 280, 282 cocaine, 246–247 in intoxication, 62 methamphetamine,
withdrawal, 165, 223, 312 Al-Anon, 149, 265 Alcohol, Smoking, and Substance
Involvement Screening Test
(ASSIST), 32, 225 Alcohol dehydrogenase genes, 7 Alcohol use, 125–150
at-risk drinking, 137 binge drinking, 10, 40, 61, 70, 127,
129, 137, 147 cannabis use with, 276 cardiovascular disease, 133 clinical symptoms and signs,
130–131 cognition, 133 comorbidities, 13 dementia risk, 14 detoxification, 63, 138–139, 142,
144 effects on older adults, 129–133 epidemiology, 128–129 hazardous/problem drinking,
127 heavy drinking, 126–128, 132–
133, 140, 143, 146, 262 introduction, 126–128 laboratory investigations, 37 medication interactions, 40 metabolism, 129–130
252
323
324 Substance Use in Older Adults
Alcohol use (continued)
moderate alcohol consumption,
127–128, 133 opioid use comorbidity, 194 overview of interventions, 59 physiological changes with
aging, 129–130 recommendations for safe use,
127–128 standard drink, 126, 127 terminology, 126–128 use among older adults, 126 withdrawal, 63, 132, 134, 139, 143
Alcohol use disorder (AUD)
assessment, 135–138
challenges, 137–138 comprehensive evaluation,
135–136, 136
screening, 136–137
benzodiazepine use, 112 case example, 130–131 clinical symptoms and signs,
130–131 comorbidities, 131–132 definition, 133 diagnostic criteria, 133–134, 134–
135
epidemiology, 10, 129 management, 138–147
detoxification, 139 key characteristics of age-sen-
sitive, 138 overview, 138 pharmacotherapy, 139–144, 141 psychosocial interventions,
144–147
mutual-help groups, 67 pharmacotherapy, 139–144, 141
acamprosate, 141, 142 baclofen, 141, 144 disulfiram, 141, 142–143 gabapentin, 141, 143 naltrexone, 140, 141, 142 overview, 139–140 topiramate, 141, 143
psychosocial interventions, 144–
147
brief interventions, 144–145 cognitive-behavioral therapy
(CBT), 145
motivational interviewing,
145 mutual-help groups, 146 in patient treatment, 144 virtual interventions, 146–147
resources, 148–150 SBIRT (screening, brief
intervention, and referral to treatment),
Alcohol Use Disorders Identification
Test (AUDIT), 31
Alcohol withdrawal syndrome
(AWS), 63, 139, 143
Alcoholics Anonymous (AA), 67,
131, 140, 146–148, 298–299
Alprazolam, 103, 112
in case examples, 193, 223–224 misuse, 99, 215
Alzheimer’s disease, 114, 133, 165,
219, 249
American Association of Geriatric
Psychiatry, 315 American Medical Association, 316 American Psychiatric Association,
316
Position Statement on Substance Use
Disorders in Older Adults, 5
on tobacco use disorder, 178
American Society of Addiction
Medicine (ASAM), 64, 169, 234,
253 Amnesia, 43, 132, 219 Amphetamine, 241, 243–245, 249,
252, 255, 257–260
See also
Methamphetamine;
Stimulant use disorder Amphetamine salts, mixed, 260 Amphetamine use disorder, 243, 255,
257
See also Methamphetamine use
order
dis Anticholinergic medications, 39, 97,
106, 113, 223
144–145
, 32, 137
Index 325
Anticonvulsants
cocaine use disorder, 260–261 methamphetamine use disorder,
257
Antidepressants
cocaine use disorder, 258–259 methamphetamine use disorder,
256–257 polypharmacy, 106 tobacco cessation, 174
Antipsychotics
cocaine use disorder, 259–260 deprescribing, 113–114 methamphetamine use disorder,
257
Anxiety
benzodiazepines for, 217 case example, 223–224 complemetary and alternative
medicine, 176 safely addressing, 98 screening for snubstance use
comorbidity, 41, 42
Anxiolytics, for cocaine use disorder,
261 Aripiprazole, 257 Assessment, 25–51
alcohol use disorder, 135–138 background, 26–27 barriers to SUD identification,
27–30, 28–29 cannabis use, 285–287, 286, 288 comorbidities, 38–43, 42 comprehensive clinical
assessment, 34–37, 38 cultural, 296–300, 313–314 definition, 26 discussing substance use, 30–31 functional, 36 opioid use disorder, 196–197 sedative, hypnotic, or anxiolytic
use disorder, 225–226 step-by-step approach, 49 stimulant use disorder, 249–252,
253
suicide risk assessment, 43–46,
44–45
tobacco use, 165–168, 165–169 tools for safely prescribing
medications, 88 ASSIST, 32, 225 ASSIST-Lite, 225 Atomoxetine, 261 At-risk use, 2, 56, 58, 276 AUD. See Alcohol use disorder AUDIT-C, 31, 32, 137 Autonomy, 305–306 AWS (alcohol withdrawal
syndrome), 63, 139, 143
Baclofen
for alcohol use disorder, 141 for cocaine use disorder, 261 for methamphetamine use
der, 257
disor Barriers to care, 56–57, 68, 303
attitudes and social norms, 303 comorbid SUDs and psychiatric
disorders, 68
stigma, 57, 68, 226
Barriers to SUD identification, 27–30,
28–29
Beers Criteria, 39, 88, 91, 97, 218, 231 Behavioral and psychological
symptoms of dementia (BPSD), 280
Benzodiazepines
alcohol use with, 128, 139 complications in older adults,
218–219
coprescription of opioids, 103–
104, 216, 226
dementia risk, 14 deprescribing, 108–109, 111–112 detoxification, 63, 228 epidemiology, 214–216 indications in older adults, 216–
218
long-acting, 98 misuse, 215–216
, 144