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42 Dicult Airway Management forENT Surgery forNon-anesthesiologists
507
subsequent barotrauma and hemodynamic dete­rioration, especially in case of a completely obstructed airway. As such, Ventrain has been acknowledged as the lifesaver for CICV situa­tions [53].
Ventrain can ventilate through small lumen such as Tritube, trans-tracheal catheter, intubat­ing catheter, hollow bougie, or airway exchange catheter, via different airway access, either trans- tracheal by puncture or incision, through a tracheostomy, via oral or nasal route. It is used electively in upper airway surgery, improv­ing surgical eld, and maintaining adequate ventilation. It also has a side port allowing side stream capnography or measuring airway pres­sure [53].
42.6.2 Alternative Oxygenation
Techniques (THRIVE/HFNO)
42.6.2.1 Introduction
High-ow nasal cannula (HFNC) or transnasal humidied rapid insufation ventilatory exchange (THRIVE) is a new emerging device for the delivery of oxygen in acute adult medical practice. In this system, humidied oxygen is delivered at a ow rate that reaches up to 80 L/ min and an inspired concentration of oxygen up to 100%, making it a good option in hypoxic or oxygen-dependant patients. The system is also able to provide benets that are more inclusive than other devices, which includes humidica-
tion and warming of inspired gases, patient com­fort, increased compliance, effective nasopharyngeal dead space washout, and deliv­ery of low-level PEEP during use (Fig.42.12) [54]. These features allow for the support of vari­ous types of patient breathing difculties, espe­cially those at risk of respiratory deterioration [55].
Initially, this therapy has been used success­fully for the management of respiratory failure in neonatal populations. However, it is now being utilized more frequently in adult populations where it has been used to treat patients with hypoxemic respiratory failure, post-extubation in critical care units, and following major surgery to prevent pulmonary complications [56].
It has also been used as an aid for preoxy­genation of patients; by improving dead space washout and prolonging the “apneic ventila­tion” period through enhancing oxygen reserve following induction of anesthesia. This concept may be useful in patients in whom hypoxia is present prior to induction of anesthesia or highly likely following induction, such as criti­cally ill and obese patients, or in those with anticipated difcult airway whom a prolonged apneic window may result due to difculties in intubation.
Currently, HFNC therapy has a role in criti­cal care units by improving oxygenation and reducing the incidence of desaturation in patients with mild to moderate hypoxia during the period of intubation. A case series of 25
Fig. 42.12 The setup
and application of HFNC
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N. A. Shallik et al.
patients in which preoxygenation was done for 10 min prior to the induction of anesthesia, showed that the apnea period was signicantly prolonged in patients undergoing complex air­way and tracheal surgery [56]. However, there is currently no evidence available pertaining to the use of HFNC as a supportive tool in moderate risk elective intubations, such as those that may be encountered in a major head and neck surgi­cal procedures.
These populations often have difcult airways due to previous surgery, radiotherapy or obstruct­ing tumors and have a higher chance of failed intubation and difculty in securing the airway than other patients. As such, any intervention that may prolong the apneic time and reduce the risk of signicant desaturation would be helpful for this patient group [57].
42.6.2.2 Final Outcome After HFNC
Application [55]
• It increases FiO2 and maintains constant FiO2.
• It improves CO2 clearance.
• It decreases the work of breathing.
• It creates positive airway pressure.
• It helps in the washout of anatomical dead
space.
• It improves pulmonary mechanics.
• It decreases upper airway resistance.
• It helps the mucus clearance.
42.6.2.3 General Indications ofHFNC
• Preoxygenation: in all patient especially, dif-
cult airway.
• During endotracheal intubation in ICU,
Bariatric, Obstetrics, Pediatrics, etc.
• During awake intubation.
• Minor upper airway surgery using the
STRIV- Hi technique.
• Post-extubation in difcult extubation cases or
compromised respiratory patients.
• Post-extubation in long-term ICU ventilation.
• In difcult airway guidelines and algorithms.
• ARDS and Acute Hypoxemic Respiratory
Failure.
• Hypoxemia induced by severe heart failure.
• Airway instrumentation during rapid sequence
induction.
Hypoxemic and hypercapnic respiratory
• failure.
• Postoperative in OSA patients.
• Claustrophobia from NIPPV.
• Stridor or end-of-life care.
42.6.3 Tubeless Anesthesia or Tube
Free ofUpper Airway Surgery
The SponTaneous Respiration using IntraVEnous and High-ow nasal oxygen (STRIVE Hi) approach to minor upper airway surgery, which is an open airway technique, and has recently been developed to facilitate micro-laryngoscopy and endoscopic airway surgery in adults without endotracheal tube.
The use of high-ow nasal oxygen (HFNO)
is gaining popularity in anesthesia, especially in critical care, as it improves oxygenation and ventilation in both apneic or spontaneously breathing patients [58]. In apneic patients, the Transnasal Humidied Rapid Insufation Ventilatory Exchange (THRIVE) technique has been associated with a prolonged apnea time and a reduced rate of rising of end tidal carbon dioxide (ETCO2). In spontaneously breathing patients, multiple physiological benets of HFNO have been described, which include (1) an increased FiO2, (2) generation of positive air­way pressure, (3) improved respiratory mechan­ics, and (4) reduced upper airway resistance. To date, these clinical benets during spontaneous ventilation have been limited to awake patients (respiratory supportive care, preoperative pre­oxygenation, postoperative support), sedated patients [procedural bronchoscopy, or awake ber-optic intubation (AFOI) or asleep patients with obstructive sleep apnea (OSA). The use of HFNO in spontaneously breathing patients undergoing general anesthesia has not been pre­viously described.
Spontaneous respiration using intravenous
anesthesia is the primary technique used at our institution for tubeless airway surgery. We did more than 150 patients using this technique without any complications. Although we have found spontaneous ventilation to be associated
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42 Dicult Airway Management forENT Surgery forNon-anesthesiologists
509
with numerous benefits, general anesthesia can have detrimental effects on respiratory mechanics, which may limit the application of the technique in certain patient subgroups, particularly those with severe respiratory comorbidity.
Propofol associated with reduced tidal and minute ventilation, decreases respiratory fre­quency and an upper airway prone to collapse. We hypothesized that the clinical benets of HFNO to oxygenation, ventilation and upper air­way patency described in awake and sedated patients would be ideally suited to spontaneously breathing patients undergoing general anesthesia. We report our initial experience combining HFNO with our previously described spontane­ous respiration technique using intravenous anes­thesia in patients undergoing micro-laryngoscopic surgery [59].
Take Home Messages
• Airway management is challenging, being able to recognize and anticipate the difculty makes the whole process efcient and safe. Difcult airway can be due to difculty with mask ventila­tion, use of supraglottic device, tracheal intubation or extubation.
• The familiarity with airway equipment is of paramount important, including the different types of supraglottic devices, direct and indirect laryngoscopes. Providers who deal with airway should be familiar with the recent equipment and recent techniques including the use of apneic oxygenation techniques.
• It is worth mentioning that difcult air­way management is a vast chapter with much extensive topics requiring a sepa­rate textbook for full discussion. Due to editing limitations in this chapter, we summarize the basic ideas and manage­ments relevant to the ENT surgeon’s day-to-day practice focusing on the common problems and providing a very basic guidance for a practical and safe management of difcult scenarios.
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Part V
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Laryngology and Esophagology
AL GRAWANY
Physiology oftheVoice andClinical Voice Assessment
MayedRadiAlkhafaji andDinaEmam
43
43.1 Introduction
S &  is the way of communica­tion used by people. Speech is an expression of ideas and thoughts by means of articulate vocal sounds. Speech requires movement of sound
waves through the air. Speech itself is air that is
moved from the lungs through a series of ana­tomic structures that mold sound waves into intelligible speech. This capacity can be accom­plished in any volume from a soft whisper to a loud shout by varying the force and volume of air expelled from the lungs.
43.2 Voice Physiology
• Voice=Voiced Sound+Resonance+Articul ation
Voiced sound: The basic sound produced by
vocal fold vibration is called “voiced sound.” This is frequently described as a “buzzy” sound.
Resonance: Voiced sound is amplied and
modied by the vocal tract resonators (the throat, mouth cavity, and nasal passages). The resona­tors produce a person’s recognizable voice.
M. R. Alkhafaji (*) · D. Emam ENT Department, Hamad Medical Corporation, Doha, Qatar e-mail: mradi@hamad.qa; DEmam@hamad.qa
Articulation: The vocal tract articulators (the tongue, soft palate, and lips) modify the voiced sound. The articulators produce recognizable words.
In humans, there are four main body systems involved in the production of speech.
1. The respiratory system
2. Laryngeal system
3. Articulation
4. The nervous system
The rst three systems are responsible for the physical manifestations of speech, and the ner­vous system is responsible for regulates these systems on both the conscious level.
The rhythmicity center of the medulla: The respiratory center is gray matter in the pons and the upper Medulla, controls automatic breathing consists of interacting neurons that re either during inspiration (I neurons) or expiration (E neurons)
I neurons—stimulate neurons that innervate
respiratory muscles (to bring about
inspiration)
E neurons—inhibit I neurons (to “shut down”
the I neurons and bring about expiration)
Apneustic center (located in the pons)—stim-
ulate I neurons (to promote inspiration)
Pneumotaxic center (also located in the
pons)—inhibits apneustic center and inhibits
inspiration
© Springer Nature Switzerland AG 2021 A. Al-Qahtani et al. (eds.), Textbook of Clinical Otolaryngology,
https://doi.org/10.1007/978-3-030-54088-3_43
515
516
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M. R. Alkhafaji and D. Emam
43.2.1 The Respiratory System andAirow
The respiratory system is also called the power system and it’s rule is the development and main­tenance of a column of air under pressure, which is presented to the glottis and subglottis, whereas the diaphragm is the important muscle for inspi­ration and expirationand in particular con­trolled expirationis necessary for vocalization.
The relaxing diaphragm interact with the mus­cles of expiration along with the natural elastic recoil of the act of expiration, also the abdominal muscles play an important rule especially the inner most layers especially in sustaining a long or powerful sound.
• Contraction of external intercostal mus-
cles>elevation of ribs and sternum>increased
front- to-back dimension of thoracic cav-
ity>lowers air pressure in lungs>air moves
into lungs.
• Contraction of diaphragm>diaphragm moves
downward> increases vertical dimension of
thoracic cavity > lowers air pressure in
lungs>air moves into lungs.
This increase of volume lowers the air pres­sure in the alveoli to below atmospheric pressure. Because air always ows from a region of high pressure to a region of lower pressure, it rushes in through the respiratory tract and into the alveoli. This is called negative pressure.
Breathing changing the pressure inside the lungs relative to the pressure of the outside atmo­sphere. In contrast to inspiration, during expira­tion the diaphragm and intercostal muscles relax. This returns the thoracic cavity to its original vol­ume, increasing the air pressure in the lungs, and forcing the air out.
• Any pulmonary pathology starting from acute
upper respiratory tract infection up to the
obstructing and restrictive pulmonary diseases
can affect the power of the voice as well as
weakness in the abdominal wall muscles, also
pathology of the thoracic cage as pectus exca-
vatum and kyphosis along with calcications
of the cartilaginous part of the ribs with age
can affect the power of the voice.
43.2.2 Vocal Folds (Also Called Vocal Cords)
The vocal cord length is varied between adults and children and between males and females.
The length in adult female is approximately 15–18mm while in males it is about 20–22mm. The vocal cords can vibrate together and create sound if they are present in the midline with the presence of subglottic pressure; the pitch is pre­dominantly determined by the stretch of the vocal cord intrinsic muscles while the power of the voice depends on the subglottic pressure.
During the adduction position which is the position of the vocal cords during vocalization there will be a small opened gap. Naturally, the thing which will make the two cords completely adducted for more clear voice is explained by the Bernolli rule which says if a stream of air passes between two surfaces that will create a negative pressure and tends to pull them together.
• So as a general rule is any factor will affect the
elasticity of the vocal cords, musculature, reg-
ularity of the surface, the completeness of the
closure or the mucus that lubricate the vocal
cords will have an impact on the voice
quality.
One vibratory cycle of the vocal cords is as follows:
• Column of air pressure opens bottom of vocal
folds
• Column of air continues to move upward, now
toward the top of vocal folds, and opens the top
• The low pressure created behind the fast-
moving air column produces a “Bernoulli
effect” which causes the bottom to close, fol-
lowed by the top
• Closure of the vocal folds cuts off the air col-
umn and releases a pulse of air
• New cycle repeats
43.2.2.1 Vocal Tract—Resonators
andArticulators
The nose, pharynx, and mouth amplify and mod­ify sound, allowing it to take on the distinctive qualities of voice the way that voice is produced is analogous to the way that sound is produced by
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43 Physiology oftheVoice andClinical Voice Assessment
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a trombone. The trombone player produces sound at the mouthpiece of the instrument with his lips vibrating from air that passes from the mouth. The vibration within the mouthpiece produces sound, which is then altered or “shaped” as it passes throughout the instrument. As the slide of the trombone is changed, the sound of the musi­cal instrument is similarly changed.
43.2.3 The Nervous System
• The brain typically formed of two cerebral hemispheres connected with nerve bers called corpus callosum. The speech centers are present mostly in the left hemisphere and in one-third of the people who are left-handed the speech is controlled by the right side of the brain.
• Parts in the brain involved in speech:
– Cerebrum: The brain is formed of lobes,
the speech is controlled by the frontal lobe and temporal lobes.
• Brocas area: an area in the frontal lobe of the dominant hemisphere on the left side of the brain, the function of this area is speech produc­tion and it is found to be the most active area immediately before you speak, even if someone has the ability to produce sound the Brocas area is necessary to express the language Brocas area is made up of Brodmann area 44 (pars opercu­laris) and 45 (pars triangularis).
– Wernicks area: Works with the angular
gyrus, insular cortex, and basal ganglion to
process word sequences to determine con­text and meaning
– Angular gyrus: Assembles information to
help us understand words and concepts
– Insular cortex: Buried underneath the outer
lobes of the cerebral cortex, the insular cor­tex is important for many functions, includ­ing motor control, emotions, and self-awareness, but also important in the pro­cessing of language
43.3 Voice Assessment inOutpatient Department
A successful voice assessment determines the cause, the severity, and the prognosis of the prob­lem and enables the planning of the most appro­priate treatment program. The voice assessment is complicated and time consuming and it cannot be done in routine ENT clinics; it needs to be done in a specialized voice clinic that is well structured and involves a diagnostic and therapeutic team. The multidisplinary team should include an ENT doctor specialized in lar­yngology, speech language pathologist, physio­therapist, psychiatrist, and a voice coach and a singing teacher who work together as a team in order to achieve a proper diagnosis and treatment for the different cases of voice disorders.
Voice assessment is multidimensional and it includes history taking, observation, clinical examination, auditory evaluation, and measure­ment of vocal cords function and physiology.
43.3.1 Voice Case History
A detailed voice history is required in order to do proper assessment and diagnosis for any patient with voice disorder and then to plan your treat­ment strategies for each case, the history should be detailed regarding the voice change, onset, course and duration, vocal cord demands and stressors, history of reux, history of special hab­its as smoking and alcohol consumption.
History should include also medications his­tory as well as the medical and surgical history especially neck surgeries and cardiothoracic surgeries.
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43.3.2 Observation (Posture, Breathing, Palpation)
Observation will include general observation for the general appearance of the patient which is a sign of the patient well-being mode and energy, fascial expressions, asymmetry or weakness, tremors, involuntary movements, frequent throat clearance, or coughing.
Position of the neck is important because of the impact on the intrinsic and extrinsic muscles of the larynx, poor posture contributes to many voice disorders and correction of posture has been part of the voice therapy for many years.
Observation should include also observation of breathing, normal breathing will insure a good power for voice production, so observation for any abnormal breathing, use of accessory respira­tory muscles, how frequent the patient inhales during conversation and if the patient is running out of air during conversation with excessive shoulder and upper chest movements listing to patient breathing can differentiate between pul­monary and laryngeal disorders.
Palpation for muscles tension is important particularly in the evaluation and treatment of muscle tension dysphonia, and palpation for ten-
sion over the temporomandibular, jaw, fascial muscles, and larynx is also important as there is a variety of protocols related to muscles tension and common sites for palpation.
43.3.3 Patient Questionnaire?
Voice disorder is very common and it has its impact on the patient lifestyle and communica­tion especially for the professional voice users and those who depend on their voice in their work as teachers, lecturers, etc.
In most of the specialized voice centers, there will be a questionnaire in order to help the diag­nosis and plan the treatment and also to follow up the patient in order to see the improvement and also to facilitate researches.
The questionnaires can be created by each center, but there are well-known questionnaires known worldwide such as Vocal Performance Questionnaire, Voice Handicap Index, and Voice Symptoms Scale.
43.3.4 Endoscopic Evaluation
withaNasopharyngoscopy andVideo Stroboscope
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