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of tests is the hepatic panel, which includes several tests to determine liver
function. A metabolic profile is a common example of a profile. A basic metabolic
profile tests only the analytes needed to make an initial assessment. A compre-
hensive metabolic profile provides additional tests to assess more body systems.
The laboratory tests included in test panels and test profiles are based on
the diagnostic needs of the laboratory’s physician clients. In addition, test profiles and panels may change in response to changes in physicians’ needs and
changes in industry standards. Therefore, the examples of test profiles and
panels in Table 5-13 may not be identical to those in the test panels and profiles available at every laboratory.
TABLE Common Test Panels and Profiles
Name of Panel or Profile Included Tests
Test Panels
Coagulation panel (Activated) partial thromboplastin time (APPT, PTT)
Fibrinogen (Fibr)
Prothrombin time (PT)
Platelet count
Hepatitis panel Hepatitis A virus antibody, IgM
Hepatitis B virus core antibody, IgM
Hepatitis B virus surface antigen
Hepatitis C virus antibody
Hypercoagulation panel All tests in the coagulation panel, plus:
Anticardiolipin antibody
APC resistance
Inhibitor status (ATIII, protein C, protein S)
Factor assays (V, VIII)
Gene mutation studies (prothrombin, Factor V Leiden)
Homocysteine Lupus anticoagulant studies
Methyltetrahydrofolate reductase (MTHFR)
Lipid panel Cholesterol (Chol)
HDL
LDL
VLDL
Triglycerides (Trig)
Liver panel Albumin
Alkaline phosphatase (ALP)
Alanine aminotransferase (ALT)
Aspartate aminotransferase (AST)
Gamma-glutamyltransferase (GGT)
Bilirubin (total and direct)
Total protein
Obstetrics (OB) panel ABO group/Rh type
Antibody screen
Complete blood count (CBC, including differential)
Cystic fibrosis gene mutation (according to family history)
Hepatitis B surface antigen
Rapid plasma reagin (RPR)
Rubella IgG
Chapter Body Systems and Related Laboratory Tests
Copyright © 2019 by McGraw-Hill Education
Name of Panel or Profile Included Tests
Test Panels
Renal panel Albumin
Blood urea nitrogen (BUN)
Calcium
Creatinine
Glucose
Electrolytes (Cl, CO2, Na, K)
Phosphorus
Respiratory virus panel Adenovirus
Coronaviruses (HKU1, NL63, 229E, OC43)
Human rhinovirus/enterovirus
Influenza (A, A/H1, A/H3, B, H1N1)
Parainfluenza virus (1, 2, 3, 4)
Respiratory syncytial virus (A, B)
Test Profiles
Basic metabolic profile
(BMP)
Comprehensive metabolic
profile (CMP)
Blood urea nitrogen (BUN)
Calcium (Ca)
Carbon dioxide (CO2) in the form of bicarbonate (HCO3)
Chloride
Creatinine
Glucose
Potassium (K)
Sodium (Na)
All tests in the basic metabolic profile, plus:
Albumin
Alanine aminotransferase (ALT)
Alkaline phosphatase (ALP)
Asparate amino transferase (AST)
Bilirubin
Total protein
1. What is the difference between a profile and a panel?
2. Look again at the digestive system information earlier in the chapter. What tests may be included in a panel designed to determine if
patients have malabsorption?
Checkpoint
Questions .
Copyright © 2019 by McGraw-Hill Education
Chapter Body Systems and Related Laboratory Tests
Chapter Summary
Learning Outcome Summary
Related
NAACLS
Competency
. Describe the functions of the
integumentary system, common
diseases and disorders that affect
this system, and related laboratory
tests.
. Describe the functions of the
skeletal system, common diseases
and disorders that affect this
system, and related laboratory
tests.
. Describe the functions of
the muscular system, common
diseases and disorders that affect
this system, and related laboratory
tests.
. Describe the functions of the
lymphatic and immune systems,
common diseases and disorders
that affect these systems, and
related laboratory tests.
. Describe the functions of
the respiratory system, common
diseases and disorders that affect
this system, and related laboratory
tests.
. Describe the functions of
the digestive system, common
diseases and disorders that affect
this system, and related laboratory
tests.
. Describe the functions of the
nervous system, common diseases
and disorders that affect this
system, and related laboratory
tests.
. Describe the functions of
the endocrine system, common
diseases and disorders that affect
this system, and related laboratory
tests.
. Describe the functions of the
cardiovascular system, common
diseases and disorders that affect
this system, and related laboratory
tests.
The integumentary system consists of the skin, hair, and nails.
Common disorders include viruses that affect the skin, allergies,
and cancer. Commonly ordered laboratory tests are listed in
Table 5 -1.
The skeletal system consists of bones, associated cartilages,
ligaments, and joints. Common disorders include osteoporosis,
osteoarthritis and rheumatoid arthritis, gout, osteosarcoma, and
nutritional deficiencies. Commonly ordered laboratory tests are
listed in Table 5-2.
The muscular system consists of the muscles and connective
tissue, including tendons and ligaments. Common disorders
include strains and sprains, tendonitis, torticollis, fibromyalgia,
myasthenia gravis, and muscular dystrophy. Commonly ordered
laboratory tests are listed in Table 5-3.
The organs of the lymphatic and immune systems include the
thymus, lymph nodes, lymphatic vessels, glands, tonsils, and
spleen. The immune system protects the body against harmful
microorganisms by producing antibodies against specific antigens.
The lymphatic system removes foreign substances from the
blood and lymph. Mononucleosis, HIV/AIDS, and lymphedema
are examples of diseases that affect these systems. Commonly
ordered laboratory tests are listed in Table 5-4.
The respiratory system includes the lungs, trachea, bronchi,
bronchioles, and nasal and oral cavities. Common disorders
include upper respiratory infections, bronchitis, pneumonia,
lung cancer, and chronic obstructive pulmonary disease (COPD).
Commonly ordered laboratory tests are listed in Table 5-5.
The digestive system organs are the mouth, pharynx,
esophagus, stomach, small intestine, large intestine, rectum,
and anus; the accessory organs are the teeth, tongue, salivary
glands, liver, gallbladder, and pancreas. Common disorders
include diabetes mellitus, ulcers, gastroesophageal reflux
disease (GERD), and hepatitis. Commonly ordered laboratory
tests are listed in Table 5-6.
The central nervous system consists of the brain and the spinal
cord; the peripheral nervous system consists of the cranial
nerves and spinal nerves. Disorders of the nervous system
include cerebrovascular accident (CVA, stroke), Alzheimer’s
disease, and sciatica. Commonly ordered laboratory tests are
listed in Table 5-7.
The endocrine glands include the hypothalamus, pituitary, pineal
body, thyroid, parathyroid, thymus, adrenal cortex, adrenal medulla,
pancreas, ovaries, and testes. Most disorders of the endocrine
system are caused by glands either oversecreting or undersecreting
their hormones. Commonly ordered laboratory tests are listed in
Table 5-9.
The cardiovascular system consists of the heart and the blood
vessels. Common diseases and disorders include heart failure,
myocardial infarction (heart attack), and coronary artery disease.
Commonly ordered laboratory tests are listed in Table 5-10.
1.00, 1.6, 3.00,
3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
Copyright © 2019 by McGraw-Hill Education
Chapter Body Systems and Related Laboratory Tests
Learning Outcome Summary
Related
NAACLS
Competency
. Describe the functions of the
urinary system, common diseases
and disorders that affect this
system, and related laboratory
tests.
. Describe the functions of
the female and male reproductive
systems, common diseases and
disorders that affect these systems,
and related laboratory tests.
. Explain the use of test panels
and profiles in the assessment of
specific body systems and general
health screening.
The urinary system includes the kidneys, bladder, ureters, and
urethra. Common diseases and disorders include renal failure,
glomerulonephritis, urinary tract infections, kidney stones, and
cystitis. Commonly ordered laboratory tests are listed in
Ta ble 5 -11.
The female reproductive system consists of the ovaries, vagina,
uterus, mammary glands, and associated structures. The male
reproductive system consists of the testes, accessory structures,
ducts, and penis. Common diseases and disorders include
infertility, sexually transmitted infections (STIs), and cancer of the
various organs. Commonly ordered laboratory tests are listed in
Table 5 -12 .
Test panels are groups of laboratory tests ordered together to
assess a single organ or body system. Test profiles are similar, but
are used to assess two or more body systems.
1.6, 3.00, 3.1
1.6, 3.00, 3.1
1.6, 3.00, 3.1
Copyright © 2019 by McGraw-Hill Education
Chapter Body Systems and Related Laboratory Tests
Chapter Review
17
18
19
20
21
22
23
24
25
26
A: Labeling
Label the parts of the respiratory, cardiovascular, and endocrine systems in the following images.
1. [LO 5.5]
2. [LO 5.5]
3. [LO 5.5]
4. [LO 5.5]
5. [LO 5.5]
6. [LO 5.5]
7. [LO 5.5]
8. [LO 5.9]
9. [LO 5.9]
10. [LO 5.9]
11. [LO 5.9]
12. [LO 5.9]
1
8
9
10
11
2
3
4
5
6
7
13
14
15
13. [LO 5.9]
14. [LO 5.9]
15. [LO 5.9]
16. [LO 5.9]
17. [LO 5.8]
18. [LO 5.8]
19. [LO 5.8]
20. [LO 5.8]
21. [LO 5.8]
22. [LO 5.8]
23. [LO 5.8]
24. [LO 5.8]
25. [LO 5.8]
12
16
26. [LO 5.8]
Chapter Body Systems and Related Laboratory Tests
Copyright © 2019 by McGraw-Hill Education
B: Matching
Match each organ with its corresponding body system. Some organs may belong to more than one system. [LOs 5.1, 5.2, 5.3, 5.4, 5.5, 5.6, 5.7, 5.8, 5.9, 5.10, 5.11]
27. adrenals
28. biceps
29. bladder
30. brain
31. epididymis
32. femur
33. hair
34. heart
35. larynx
36. liver
37. penis
38. pharynx
39. quadriceps
a. cardiovascular
b. digestive
c. endocrine
d. integumentary
e. lymphatic
f. muscular
g. nervous
h. reproductive
i. respiratory
j. skeletal
k. urinary
40. salivary glands
41. skull
42. spinal cord
43. spleen
44. tonsils
45. ureter
46. uterus
47. vagina
C: Fill in the Blank
Write in the word(s) to complete each statement.
48. [LO 5.5] The organ in which gas exchange takes place is the .
49. [LO 5.10] Liquid wastes are stored in and eliminated by the .
50. [LO 5.1] The largest organ in the body is the .
51. [LO 5.11] Reproductive organs specific to the female include the .
Copyright © 2019 by McGraw-Hill Education
52. [LO 5.11] Reproductive organs specific to the male include the .
Chapter Body Systems and Related Laboratory Tests
D: Sequencing
Indicate the sequence through which food passes through the digestive system (from 1 through 7).
53. [LO 5.6] anus
54. [LO 5.6] esophagus
55. [LO 5.6] large intestine
56. [LO 5.6] oral cavity
57. [LO 5.6] rectum
58. [LO 5.6] small intestine
59. [LO 5.6] stomach
E: Case Studies/Critical Thinking
60. [LO 5.7] A patient cannot feel any pain when you draw her blood. She explains that she does not feel
light sensations or pressure when touched on her arms or legs. A disorder in which body system(s) may
be causing this issue?
61. [LO 5.3] An elderly patient, living a sedentary lifestyle (lack of activity), is feeling very cold and does not
produce much of his own body heat. Explain which body system may be contributing to this and why.
62. [LO 5.1, 5.3, 5.7, 5.9] Which body systems does a phlebotomist use when drawing blood? Explain the
reasons for each system in your answer.
63. [LO 5.1, 5.7, 5.9] When drawing blood on a patient, with which of the patient’s body systems does the
equipment come in contact?
64. [LO 5.11] A 35-year-old female patient has been trying to get pregnant since she got married two years
ago. She does not have children and she would like to have a child before her biological clock stops
ticking. The physician needs to determine what might be the cause of her infertility (inability to get
pregnant). What system of the body needs to be evaluated and what related laboratory tests would most
likely need to be drawn for the patient and her husband?
65. [LO 5.9] A 65-year-old male presents in the emergency room with chest pain, shortness of breath, and
profuse sweating. What system of the body needs to be evaluated and what laboratory tests would most
likely be drawn stat (immediately)?
F: Exam Prep
Choose the best answer for each question.
66. [LO 5.6] Which of the following blood tests aids
in the evaluation of the digestive system?
a. Albumin
b. Creatinine
c. Hemoglobin
d. Uric acid
67. [LO 5.10] The renal tubules are part of which
body system?
a. Cardiovascular
b. Digestive
c. Respiratory
d. Urinary
Chapter Body Systems and Related Laboratory Tests
Copyright © 2019 by McGraw-Hill Education
68. [LO 5.5] One of the blood tests used primarily to
evaluate the respiratory system is abbreviated
75. [LO 5.7] Word parts that refer to the nervous
system include all of these except
a. ABG.
b. BN P.
c. CBC.
d. EPO.
69. [LO 5.2] Cartilage and ligaments are part of
which body system?
a. Cardiovascular
b. Muscular
c. Respiratory
d. Skeletal
70. [LO 5.3] Connective tissue and tendons are part
of which body system?
a. Cardiovascular
b. Muscular
c. Respiratory
d. Skeletal
71. [LO 5.5] Oxia, capnia, pnea, and spiro are word
parts that refer to which body system?
a. Cardiovascular
b. Endocrine
c. Respiratory
d. Urinary
72. [LO 5.6] The liver and gallbladder are part of
which body system?
a. Digestive
b. Endocrine
c. Respiratory
d. Urinary
73. [LO 5.6] A panel of tests used to assess liver
function may include all of these except
a. ammonia.
b. bilirubin.
c. creatine kinase.
d. lactate dehydrogenase.
74. [LO 5.8] Laboratory tests used to assess the
endocrine system include all of these except
a. cranio-.
b. encephalo-.
c. myo-.
d. neuro-.
76. [LO 5.1] Regulation of body heat occurs in the
a. cardiovascular system.
b. digestive system.
c. integumentary system.
d. muscular system.
7 7. [LO 5.2] You receive an order to draw blood
on a patient for alkaline phosphatase, calcium,
phosphorus, and vitamin D. The physician is
most likely concerned about the patient’s
a. cardiovascular system.
b. digestive system.
c. muscular system.
d. skeletal system.
78. [LO 5.5] The trachea and bronchi are part of the
a. cardiovascular system.
b. lymphatic system.
c. respiratory system.
d. skeletal system.
79. [LO 5.5] A sputum culture will detect infections
in the
a. digestive system.
b. endocrine system.
c. lymphatic system.
d. respiratory system.
80. [LO 5.9] The body system responsible for carrying
oxygen, nutrients, and waste products is the
a. cardiovascular system.
b. digestive system.
c. respiratory system.
d. urinary system.
81. [LO 5.8] Other body systems are influenced by
chemicals and hormones produced in the organs
of the
a. aldosterone.
b. B-type natriuretic peptide.
c. cortisol.
d. erythropoietin.
Copyright © 2019 by McGraw-Hill Education
a. cardiovascular system.
b. endocrine system.
c. lymphatic system.
d. respiratory system.
Chapter Body Systems and Related Laboratory Tests
82. [LO 5.7] Providing communication via a series of
electrical impulses is the main function of the
a. digestive system.
b. integumentary system.
c. muscular system.
d. nervous system.
83. [LO 5.10] Maintaining a balance of water, salts,
and acids is the function of the
a. digestive system.
b. integumentary system.
c. respiratory system.
d. urinary system.
84. [LO 5.1] Dermatitis and athlete’s foot are
disorders of the
a. digestive system.
b. integumentary system.
c. reproductive system.
d. skeletal system.
86. [LO 5.12] A test panel that includes a platelet
count, fibrinogen, prothrombin time, and
activated partial thromboplastin time is most
likely which of the following?
a. Hepatitis panel
b. Basic metabolic profile
c. Coagulation panel
d. Renal panel
87. [LO 5.12] A series of tests that includes
creatinine, blood urea nitrogen, albumin,
glucose, and total protein is most likely which of
the following?
a. Obstetrics panel
b. Liver panel
c. Basic metabolic profile
d. Comprehensive metabolic profile
85. [LO 5.10] If the function of the urinary system is
in question, the tests that would be most helpful
include all of these except
a. BUN.
b. creatinine.
c. glucose.
d. osmolality.
Enhance your learning by completing these exercises and more at
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References
Booth, K. A. (2013). Healthcare science technology. New York, NY: McGraw-Hill.
Booth, K. A., Whicker, L. G., & Wyman, T. D. (2017). Medical assisting: Administrative and clinical procedures with anatomy and
physiology (6th ed.). New York, NY: McGraw-Hill.
Burtis, C. A., & Burns, D. E. (2015). Tietz fundamentals of clinical chemistry and molecular diagnostics (7th ed.). St. Louis, MO:
Saunders.
National Accrediting Agency for Clinical Laboratory Sciences. (2016). NAACLS entry-level phlebotomist competencies. Retrieved
February 2, 2017, from www.naacls.org/getattachment/d5a69a7a-7323-439e-9db8-1f0ea000b718/2012-Standards-Edited.aspxf
Sheir, D. (2011). Hole’s essentials of human anatomy & physiology (11th ed.). New York, NY: McGraw-Hill.
Thierer, N. (2010). Medical terminology: Language for healthcare (3rd ed.). New York, NY: McGraw-Hill.
Design Elements: Safety & Infection Control icon (samples in hand) ©motorolka/Shutterstock.com RF.
Chapter Body Systems and Related Laboratory Tests
Copyright © 2019 by McGraw-Hill Education
6
The Cardiovascular System
agglutination
antecubital fossa
antibody
anticoagulant
antigen
aorta
arteriole
artery
atrium (atria)
basilic vein
basophil
essential terms
B lymphocyte (B-cell)
biconcave
blood type
capillary
centrifugation
cephalic vein
coagulation
cytoplasm
deoxygenated
diapedesis
eosinophil
erythrocyte
fibrin
fibrinogen
granulocyte
hematoma
hematopoietic
hemoglobin
hemolysis
hemostasis
jaundice
leukocyte
lymphocyte
lymphoid
median cubital vein
monocyte
mononuclear
myeloid
natural killer (NK)
cell
neutrophil
oxygenated
phagocytosis
plasma
polymorphonuclear
pulmonary artery
pus
Rh antigen
septum
serum
T lymphocyte (T-cell)
thrombin
thrombocyte
tunica adventitia
tunica intima
tunica media
valves
vein
venae cavae
ventricles
venule
©Hank Grebe/Getty Images
Learning Outcomes
. Describe circulation and the purpose of the
vascular system.
. Identify and describe the structures and
functions of the different types of blood
vessels.
. Locate and name the veins most commonly
used for phlebotomy procedures.
. Identify the major components of blood and
describe the major functions of each.
. Define hemostasis and describe the basic
coagulation process.
. Describe how ABO and Rh blood types are
determined.