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and female, she still only meets 1 of the 4 criteria of the diagnos-
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tic rule for vertebral fracture as proposed by Henschke et al.
212
While a gentle exercise program that the patient can progress from is more appropriate than bed rest, it is still important to make sure to rule out any other serious pathology that might be present.
2.
After 2 weeks of treatment, your patient was not seeing the results she was expecting and went to get an MRI. e re­sults were positive for degenerative disc disease at multiple levels with Modic changes (type 1) at L4. You should:
a. Educate the patient that at her age the presence of degen-
erative discs and Modic changes are common and do not often correlate to symptoms.
b. Refer the patient to a behavior health specialist to manage
her psychosocial comorbidities.
c. Inform the patient that she is unlikely to receive any help
from physical therapy due to the spinal structural changes associated with her pain.
Refer to an orthopedic surgeon to explore more invasive
d.
options.
e correct answer is a. Educate the patient that at her
age the presence of degenerative discs and Modic changes are common and do not often correlate to symptoms. For
this patient, due to her age, both degenerative discs and Mod­ic changes are very common and are rarely associated with symptoms. e presence of these conditions does not indicate that she is unable to receive benefit from physical therapy. She should be encouraged by the fact that many people who have degenerative discs and Modic changes walk around with no pain and that physical therapy is going to work to get her to that place. Furthermore, there is no indication from the information provided that this patient needs higher skilled care to address any psychosocial comorbidities.
3.
e patient understands about the Modic changes but she is nervous about the “high intensity zone (HIZ)” that her physician pointed out. e HIZ is:
a. Where a portion of the disc material is beyond the disc
space and is no longer connected to the remaining disc.
b. A high signal contained within the annulus of a disc, sep-
arated from the nucleus pulposus, on lumbar spine MRI.
c. Where a portion of the disc material has extruded beyond
the circumference of the disc space.
d. A positive indication of vertebral end-plate inflammation.
e correct answer is b. A high signal contained within
the annulus of a disc, separated from the nucleus pulposus, on lumbar spine MRI. e hypothesized mechanism is that
the HIZ is indicative of a tear in the structurally weak posterior annulus. However, approximately 1 in 4 individuals without LBP have a HIZ in their lumbar spine.
After reassuring the patient that the findings on her MRI
4. are likely to reflect her age and are not indicative of a patho­logical process, you resume therapy. Up until now the pa­tient has been primarily performing motor control exercises. However, due to the lack of progress, the patient notes that this time she wants a different approach. She had a previous therapist that used a directional-based exercise approach and she noticed that she received a lot of benefit from those exer­cises. erefore, you should:
a.
Continue with the motor control exercises as that is what you feel will work the best for this patient.
Insist to the patient that you know best and continue with
b.
stabilization exercises.
c.
Listen to the patient’s concerns and, taking her previous experiences into account, switch her exercise program to one that matches the directional-based exercise approach.
d. Switch to general exercise because all the approaches have
demonstrated equal efficacy.
e correct answer is c. Listen to the patient’s concerns
and, taking her previous experiences into account, switch her exercise program to one that matches the directional­based exercise approach. While it is true that all approaches
seem to have equal efficacy in the treatment of LBP, do not for­get about the third pillar of evidence: patient values. By listen­ing to the patient, you are also actively engaging in building the therapeutic alliance that can pay dividends in your treatment.
Case Scenario 3
Your patient is a 49-year-old female with cLBP. On a typ­ical day, her pain is at a 4/10 but about twice a month it will flare up to a 9/10. She started to have symptoms about 15 years ago with no clear method of injury. At the time she had an MRI that was positive for a bulging disc at L4-5. She reports working in a high-paced sales position where she is under constant pres­sure to make sales. She has 2 kids, ages 18 and 16, and reports being too busy to get in any regular exercise. She notes that ever since having kids her sleep has been interrupted.
Just given the information above, what should be one of your
1.
next steps regarding the patient?
a. Refer the patient back for further physician review due to
the chronicity of the symptoms without any relief and no clear mechanism of injury.
b. e patient should be given either the FABQ, PCS, or
the OSPRO-YF to determine the extent of the presence of yellow flags or psychosocial risk factors.
c. e patient has underlying psychosocial factors that neces-
sitate referral to a behavioral health specialist.
d. Continue to treat and evaluate the patient with no more
information.
e correct answer is b. e patient should be given ei-
ther the FABQ, PCS, or the OSPRO-YF to determine the
Academy of Orthopaedic Physical erapy, APTA. For personal use only. No other uses without permission. © 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
37
extent of the presence of yellow flags or psychosocial risk
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factors. e patient does not need to be immediately referred to the physician due to the lack of a clear mechanism of injury. Remember, most cLBP has no clear mechanism of injury. e patient so far has only reported experiencing increased stress, so getting a better understanding of the extent of the psychosocial risk factors should be a top priority. However, an immediate referral to a behavioral health specialist is unwarranted because, just like with red flags, the presence of a single yellow flag is not always serious.
2.
e patient reports that she is nervous about the bulging disc in her back. She sits with a rigid posture and does not per­form any forward flexion because she has been told by previ­ous health care workers that her disc is like a jelly doughnut and that any forward bending is going to make her disc “pop out of place.” You should:
a.
Focus on exercises that only move her into extension to accommodate her fears.
Educate her that the presence of a bulging disc is very
b.
common and no reason to be afraid; her back is strong and she should slowly start to exercise and resume regular activity.
c. Insist she get an updated MRI to assess the progression of
the bulging disc.
d. Instruct her to resist any forward flexion, prolonged sit-
ting, or lifting of heavy objects.
e correct answer is b. Educate her that the presence of
a bulging disc is very common and no reason to be afraid; her back is strong, and she should slowly start to exercise and resume regular activity. While accommodating a patient’s
preferences is a good approach, in this scenario the more appro­priate response is to educate the patient that the presence of a bulging disc is a very normal thing. She needs to be assured that by bending forward she is not going to damage her spine. An updated MRI will be of little diagnostic value, and continuing the education of resisting forward flexion, prolonged sitting, or heavy lifting will only promote her kinesiophobia and impair her function.
3. e patient states that she has noticed a positive correlation between her stress levels and her LBP. While the evidence is not yet conclusive, one treatment option to specifically address this issue could be:
a. Mindfulness based stress reduction training. b. Dry needling. c. Aerobic exercise. d. Spinal mobilization.
evidence has shown that mobile applications can be effective for patients, it represents a cheap and easily accessible treatment option for many. While dry needling, aerobic exercise, and spi­nal mobilization are all valid treatment options for this patient, they do not specifically address the increased stress.
4. e patient has been working with you for 4 weeks now and is ready to be discharged. During her time in therapy, you have used a combination of transcutaneous electrical nerve stimulation (TENS), therapeutic exercises, dry needling, and myofascial release. While she now has a better grasp on her stress levels, her day is still very demanding and she only has time to incorporate 1 of your interventions into her daily life. Which should she choose?
a.
She should continue to see an acupuncturist to receive
needling therapy. b. She should buy a TENS unit so she can use it at home. c. She should routinely visit a massage therapist for soft
tissue work.
She should incorporate physical activity into her daily life.
d.
e correct answer is d. She should incorporate physical activity into her daily life. While all the other options are val­id treatment approaches, the patient should prioritize exercise. Almost all guidelines recommend continued exercise for those with cLBP.
Case Scenario 4
Your patient is a 72-year-old female who recently slipped in her kitchen while putting away some dishes. She made it through the night but was in significant pain even after taking some acetaminophen. She presents to your clinic with com­plaints of 8/10 pain that is localized in her mid-lumbar region. She denies having any lower extremity pain or weakness. Prior to the fall she was an avid gardener and enjoyed daily walks.
1.
Given this information, what is your first course of action?
a. Screen her for additional red flags as her losing balance
might be indicative of serious pathology.
b. Treat with heat and TENS while in the acute phase, work-
ing your way into gentle therapeutic exercise.
c. Refer her to her physician for radiographs.
Perform spinal manipulation as this is a patient with
d.
acute LBP.
e correct answer is c. Refer her to her physician for radiographs. is patient is exhibiting 2 out of the 3 red flags for a vertebral fracture (age >70 years and significant trauma). Furthermore, given her female sex, the positive likelihood ratio of having a fracture is 218.3.
e correct answer is a. Mindfulness based stress reduc- tion training. While the case for MBSR is still growing, there is emerging evidence that it may be beneficial. Also, because
2. What is the other red flag that would indicate your patient might have a fracture?
a. Prolonged corticosteroid use.
Academy of Orthopaedic Physical erapy, APTA.
38
© 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
For personal use only. No other uses without permission.
b. A body mass index of less than 20 kg/m2.
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c.
A low Berg-Balance score.
A self-selected walking speed of less than 0.5 m/s.
d.
e correct answer is a. Prolonged corticosteroid use. While the remaining choices could indicate a greater poten­tial for a fall risk or increased fracture risk in general, only the prolonged corticosteroid use was found to be correlated with increased risk for fracture.
3.
e patient plain film radiograph came back positive for a fracture. e physician put her in a lumbosacral corset for 10 weeks to be followed up with physical therapy. Following the 10 weeks her pain is at a 6/10 but she is now very weak. What would be the best course of action?
Advise the patient to take an additional 2 weeks of bed rest
a.
to transition out of having the lumbosacral corset.
b. Focus her remaining visits on passive modalities to reduce
her sensitivity.
c. Focus solely on motor control exercises to compensate for
spinal weakness.
d.
Any combination of motor control exercises, graded exer­cises, or a walking program to incorporate exercise back into her treatment regimen.
e correct answer is d. Any combination of motor con-
trol exercises, graded exercises, or a walking program to in­corporate exercise back into her treatment regimen. All the
choices are appropriate exercises to get the patient back into exercising, each with the ability to provide good results. As the patient is undoubtably weak, motor control exercises can serve
to strengthen her abdominals. Taking the patient’s interests and hobbies into consideration is also a good strategy when devel­oping an exercise routine. According to the guidelines, the most important aspect to rehabilitating LBP is to get the patient performing exercise while encouraging resumption of normal activities.
After 2 weeks of therapy, your patient has made limited
4. progress. She reports that she is reluctant to go for a walk because she is afraid that she might fall again. Furthermore, she notes that her exercises temporarily increase her pain and she is afraid that she is making the situation worse by doing her exercises. What would be your best course of action?
a. Tell her that the best way for her spine to fully heal is
through controlled loading to facilitate bone health.
b.
Educate her on the importance of aerobic exercise for general well-being.
Discharge her for non-compliance.
c. d.
Educate your patient about her pain, how the pain she experiences during exercises does not always mean she is harming her back, and provide other education centered around pain neuroscience education (PNE).
e correct answer is d. Educate your patient about her
pain, how the pain she experiences during exercises does not always mean she is harming her back, and provide other ed­ucation centered around PNE. is patient is exhibiting some
“yellow flags” relating to fear and anxiety about exercise. While the evidence is still building, PNE can provide a path for this patient to reengage in exercise without the fear of further dam­aging her spine.
1. Collaborators. GDaIIaP. Global, regional, and national inci­dence, prevalence, and years lived with disability for 354 dis­eases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study
2017. Lancet (London, England). 2018;392(10159):1789-1858. doi: 10.1016/S0140-6736(18)32279-7
2. Mokdad AH, Ballestros K, Echko M, et al. e state of US health, 1990-2016: Burden of Diseases, Injuries, and Risk Fac­tors Among US States. JAMA. 2018;319(14):1444-1472. doi:
10.1001/jama.2018.0158
3. Hoy D, Bain C, Williams G, et al. A systematic review of the global prevalence of low back pain. Arthritis Rheum. 2012;64(6):2028-2037. doi: 10.1002/art.34347
4. Freburger JK, Holmes GM, Agans RP, et al. e rising prevalence of chronic low back pain. Arch Intern Med. 2009;169(3):251-258. doi: 10.1001/archinternmed.2008.543
Academy of Orthopaedic Physical erapy, APTA. For personal use only. No other uses without permission. © 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
REFERENCES
5. Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J. 2008;8(1):8-20. doi: 10.1016/j. spinee.2007.10.005
6. Martin BI, Turner JA, Mirza SK, Lee MJ, Comstock BA, Deyo RA. Trends in health care expenditures, utilization, and health status among US adults with spine problems, 1997-2006. Spine (Phila Pa 1976). 2009;34(19):2077-2084. doi: 10.1097/ BRS.0b013e3181b1fad1
7. Davis MA, Onega T, Weeks WB, Lurie JD. Where the United States spends its spine dollars: expenditures on different ambu­latory services for the management of back and neck condi­tions. Spine (Phila Pa 1976). 2012;37(19):1693-1701. doi:
10.1097/BRS.0b013e3182541f45
8. Murray CJ, Atkinson C, Bhalla K, et al. e state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA. 2013;310(6):591-608. doi: 10.1001/jama.2013.13805
39
9. Deyo R, Mirza S, Martin B. Back pain prevalence and visit
https://t.me/med1917
rates: estimates from U.S. National Surveys, 2002. Spine. 2006;31:2724-2727. doi: 10.1097/01.brs.0000244618.06877. cd Jette AM, Smith K, Haley SM, Davis KD. Physical therapy
10. episodes of care for patients with low back pain. Phys er. 1994;74(2):101-110; discussion 110-105. doi: 10.1093/ ptj/74.2.101
11.
Yang H, Haldeman S, Lu ML, Baker D. Low back pain prev­alence and related workplace psychosocial risk factors: a study using data from the 2010 National Health Interview Survey. J Manipulative Physiol er. 2016;39(7):459-472. doi: 10.1016/j. jmpt.2016.07.004 Walker BF. e prevalence of low back pain: a systematic
12. review of the literature from 1966 to 1998. J Spinal Disorders. 2000;13(3):205-217. doi: 10.1097/00002517-200006000­00003
13.
Andersson GB. Epidemiological features of chronic low-back pain. Lancet. 1999;354(9178):581-585. doi: 10.1016/S0140­6736(99)01312-4 Meucci RD, Fassa AG, Faria NM. Prevalence of chronic low
14. back pain: systematic review. Rev Saude Publica. 2015;49:1. doi:
10.1590/S0034-8910.2015049005874
15.
Brandão T, Campos L, de Ruddere L, Goubert L, Bernardes SF. Classism in pain care: the role of patient socioeconomic status on nurses’ pain assessment and management practices. Pain Med. 2019;20(11):2094-2105. doi: 10.1093/pm/pnz148
16.
Schofield DJ, Callander EJ, Shrestha RN, Percival R, Kelly SJ, Passey ME. Labor force participation and the influence of having back problems on income poverty in Australia. Spine (Phila Pa 1976). 2012;37(13):1156-1163. doi: 10.1097/ BRS.0b013e31824481ee
17. Shraim M, Cifuentes M, Willetts JL, Marucci-Wellman HR, Pransky G. Regional socioeconomic disparities in outcomes for workers with low back pain in the United States. Am J Industr Med. 2017;60(5):472-483. doi: 10.1002/ajim.22712 Anastas TM, Miller MM, Hollingshead NA, Stewart JC, Rand
18. KL, Hirsh AT. e unique and interactive effects of patient race, patient socioeconomic status, and provider attitudes on chronic pain care decisions. Ann Behav Med. 2020;54(10):771-
782. doi: 10.1093/abm/kaaa016
19. Carey TS, Freburger JK, Holmes GM, et al. Race, care seeking, and utilization for chronic back and neck pain: population perspectives. J Pain. 2010;11(4):343-350. doi: 10.1016/j. jpain.2009.08.003
20.
Green CR, Baker TA, Sato Y, Washington TL, Smith EM. Race and chronic pain: A comparative study of young black and white Americans presenting for management. J Pain. 2003;4(4):176-183. doi: 10.1016/s1526-5900(02)65013-8
21. Green CR, Hart-Johnson T. e association between race and neighborhood socioeconomic status in younger Black and White adults with chronic pain. J Pain. 2012;13(2):176-186. doi: 10.1016/j.jpain.2011.10.008
22. Kohns DJ, Haig AJ, Uren B, et al. Clinical predictors of the medical interventions provided to patients with low back pain in the emergency department. J Back Musculoskelet Rehabil. 2018;31(1):197-204. doi: 10.3233/BMR-170806
23. Fillingim RB, Doleys DM, Edwards RR, Lowery D. Clinical characteristics of chronic back pain as a function of gender and oral opioid use. Spine (Phila Pa 1976). 2003;28(2):143-150. doi: 10.1097/00007632-200301150-00010
24. Treede RD, Rief W, Barke A, et al. A classification of chron­ic pain for ICD-11. Pain. 2015;156(6):1003-1007. doi:
10.1097/j.pain.0000000000000160
25.
Henschke N, Maher CG, Refshauge KM, et al. Prognosis in patients with recent onset low back pain in Australian primary care: inception cohort study. BMJ. 2008;337(7662):a171. doi:
10.1136/bmj.a171 van Tulder M, Becker A, Bekkering T, et al. Chapter 3. Euro-
26. pean guidelines for the management of acute nonspecific low back pain in primary care. Eur Spine J. 2006;15 Suppl 2(Suppl
2):S169-191. doi: 10.1007/s00586-006-1071-2
27.
Waddell G. 1987 Volvo award in clinical sciences. A new clinical model for the treatment of low-back pain. Spine (Phila Pa 1976). 1987;12(7):632-644. doi: 10.1097/00007632­198709000-00002 Abbott JH, Mercer S. e natural history of acute low back
28. pain. NZ J Physiother. 2002;30(3):8-17. Croft PR, Macfarlane GJ, Papageorgiou AC, omas E, Silman
29. AJ. Outcome of low back pain in general practice: a prospec­tive study. BMJ. 1998;316(7141):1356-1359. doi: 10.1136/ bmj.316.7141.1356
30.
Balagué F, Mannion AF, Pellisé F, Cedraschi C. Non-specific low back pain. Lancet. 2012;379(9814):482-491. doi: 10.1016/ S0140-6736(11)60610-7 Hoy D, Brooks P, Blyth F, Buchbinder R. e epidemiology of
31. low back pain. Best Pract Res Clin Rheumatol. 2010;24(6):769-
781. doi: 10.1016/j.berh.2010.10.002
32.
Pengel LH, Herbert RD, Maher CG, Refshauge KM. Acute low back pain: systematic review of its prognosis. BMJ. 2003;327(7410):323. doi: 10.1136/bmj.327.7410.323
33.
Hides JA, Jull GA, Richardson CA. Long-term effects of specific stabilizing exercises for first-episode low back pain. Spine (Phila Pa 1976). 2001;26(11):E243-248. doi: 10.1097/00007632­200106010-00004
34. Downie AS, Hancock MJ, Rzewuska M, Williams CM, Lin CW, Maher CG. Trajectories of acute low back pain: a latent class growth analysis. Pain. 2016;157(1):225-234. doi:
10.1097/j.pain.0000000000000351 Correa JB, Costa LO, de Oliveira NT, Sluka KA, Liebano RE.
35. Central sensitization and changes in conditioned pain mod­ulation in people with chronic nonspecific low back pain: a case-control study. Exp Brain Res. 2015;233(8):2391-2399. doi:
10.1007/s00221-015-4309-6
36.
George SZ, Wittmer VT, Fillingim RB, Robinson ME. Fear-avoidance beliefs and temporal summation of evoked thermal pain influence self-report of disability in patients with chronic low back pain. J Occup Rehabil. 2006;16(1):95-108. doi: 10.1007/s10926-005-9007-y
37. Goubert D, Oosterwijck JV, Meeus M, Danneels L. Structural changes of lumbar muscles in non-specific low back pain: a systematic review. Pain Phys. 2016;19(7):E985-e1000.
38.
Nakamura Y, Nojiri K, Yoshihara H, et al. Significant differenc­es of brain blood flow in patients with chronic low back pain and acute low back pain detected by brain SPECT. J Orthop Sci. 2014;19(3):384-389. doi: 10.1007/s00776-014-0534-2
39. Bogduk N. Management of chronic low back pain. Med J Aus- tralia. 2004;180(2):79-83.
40. Maher CG. Effective physical treatment for chronic low back pain. Orthop Clin North Am. 2004;35(1):57-64. doi: 10.1016/ S0030-5898(03)00088-9
40
Academy of Orthopaedic Physical erapy, APTA.
© 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
For personal use only. No other uses without permission.
41. Skelly AC, Chou R, Dettori JR, et al. AHRQ Comparative
https://t.me/med1917
Effectiveness Reviews. In: Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review. Agency for
Healthcare Research and Quality (US); 2018.
42.
Foster NE, Anema JR, Cherkin D, et al. Prevention and treatment of low back pain: evidence, challenges, and promising directions. Lancet. 2018;391(10137):2368-2383. doi: 10.1016/ S0140-6736(18)30489-6 Dunn KM, Jordan K, Croft PR. Characterizing the course
43. of low back pain: a latent class analysis. Am J Epidemiol. 2006;163(8):754-761. doi: 10.1093/aje/kwj100
44. Costa Lda C, Maher CG, McAuley JH, et al. Prognosis for pa­tients with chronic low back pain: inception cohort study. BMJ. 2009;339:b3829. doi: 10.1136/bmj.b3829
45. Amirdelfan K, McRoberts P, Deer TR. e differential diagnosis of low back pain: a primer on the evolving paradigm. Neuro- modulation. 2014;17 Suppl 2:11-17. doi: 10.1111/ner.12173
46. Dutton M. Dutton’s Orthopaedic Examination, Evaluation and Intervention. 4th ed. McGraw Hill; 2016. Neumann D. Kinesiology of the Musculoskeletal System: Founda-
47. tions for Rehabilitation. Elsevier; 2017.
48.
Adams MA, Roughley PJ. What is intervertebral disc degeneration, and what causes it? Spine (Phila Pa
1976). 2006;31(18):2151-2161. doi: 10.1097/01. brs.0000231761.73859.2c
49. Cassidy J, Hiltner A, Baer E. Hierarchical structure of the in­tervertebral disc. Connective Tissue Res. 1989;23(1):75-88. doi:
10.3109/03008208909103905
50. Newell N, Little JP, Christou A, Adams MA, Adam CJ, Masouros SD. Biomechanics of the human intervertebral disc: A review of testing techniques and results. J Mechan Behavior Biomed Materials. 2017;69:420-434. doi: 10.1016/j. jmbbm.2017.01.037 Adam C, Rouch P, Skalli W. Inter-lamellar shear resistance
51. confers compressive stiffness in the intervertebral disc: An image-based modelling study on the bovine caudal disc. J Biomechs. 2015;48(16):4303-4308. doi: 10.1016/j. jbiomech.2015.10.041
52.
Melrose J, Smith SM, Appleyard RC, Little CB. Aggrecan, versican and type VI collagen are components of annular translamellar crossbridges in the intervertebral disc. Eur Spine J. 2008;17(2):314-324. doi: 10.1007/s00586-007-0538-0 Iatridis JC, Weidenbaum M, Setton LA, Mow VC. Is the
53. nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc. Spine. 1996;21(10):1174-1184. doi: 10.1097/00007632­199605150-00009
54. Pooni J, Hukins D, Harris P, Hilton R, Davies K. Comparison of the structure of human intervertebral discs in the cervical, thoracic and lumbar regions of the spine. Surg Radiol Anatomy. 1986;8(3):175-182. doi: 10.1007/BF02427846
55. Wilke HJ, Neef P, Caimi M, Hoogland T, Claes LE. New in vivo measurements of pressures in the intervertebral disc in daily life. Spine. 1999;24(8):755-762. doi: 10.1097/00007632­199904150-00005
56. Nachemson A. e influence of spinal movements on the lum­bar intradiscal pressure and on the tensile stresses in the annulus fibrosus. Acta Orthopaedica Scandinavica. 1963;33(1-4):183-
207. doi: 10.3109/17453676308999846
57.
Gruber HE, Hanley EN, Jr. Recent advances in disc cell biolo­gy. Spine (Phila Pa 1976). 2003;28(2):186-193. Moore RJ. e vertebral endplate: disc degeneration, disc
58. regeneration. Eur Spine J. 2006;15 Suppl 3(Suppl 3):S333-337. doi: 10.1097/00007632-200301150-00017
59. Grant JP, Oxland TR, Dvorak MF. Mapping the structur­al properties of the lumbosacral vertebral endplates. Spine. 2001;26(8):889-896. doi: 10.1097/00007632-200104150­00012 Rajasekaran S, Venkatadass K, Naresh Babu J, Ganesh K,
60. Shetty AP. Pharmacological enhancement of disc diffusion and differentiation of healthy, ageing and degenerated discs : Results from in-vivo serial post-contrast MRI studies in 365 human lumbar discs. Eur Spine J. 2008;17(5):626-643. doi: 10.1007/ s00586-008-0645-6
61.
Peng B, Hou S, Wu W, Zhang C, Yang Y. e pathogenesis and clinical significance of a high-intensity zone (HIZ) of lumbar intervertebral disc on MR imaging in the patient with dis­cogenic low back pain. Eur Spine J. 2006;15(5):583-587. doi:
10.1007/s00586-005-0892-8 Peng B, Hao J, Hou S, et al. Possible pathogenesis of painful
62. intervertebral disc degeneration. Spine (Phila Pa 1976). 2006; 31(5):560-566. doi: 10.1097/01.brs.0000201324.45537.46
63.
An HS, Anderson PA, Haughton VM, et al. Intro­duction: disc degeneration: summary. Spine (Phila Pa
1976). 2004;29(23):2677-2678. doi: 10.1097/01. brs.0000147573.88916.c6
64. Gübitz R, Lange T, Gosheger G, et al. Influence of age, BMI, gender and lumbar level on T1ρ magnetic Resonance imag­ing of lumbar discs in healthy asymptomatic adults. RoFo. 2018;190(2):144-151. doi: 10.1055/s-0043-115898
65. Cheung KM, Karppinen J, Chan D, et al. Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals. Spine (Phila Pa 1976). 2009;34(9):934-940. doi: 10.1097/ BRS.0b013e3181a01b3f Buckwalter JA. Aging and degeneration of the human interver-
66. tebral disc. Spine (Phila Pa 1976). 1995;20(11):1307-1314. doi:
10.1097/00007632-199506000-00022
67. Brinjikji W, Luetmer PH, Comstock B, et al. Systematic litera­ture review of imaging features of spinal degeneration in asymp­tomatic populations. AJNR Am J Neuroradiol. 2015;36(4):811-
816. doi: 10.3174/ajnr.A4173
68.
Romeo V, Covello M, Salvatore E, et al. High prevalence of spinal magnetic resonance imaging findings in asymptom­atic young adults (18-22 yrs) candidate to air force flight. Spine (Phila Pa 1976). 2019;44(12):872-878. doi: 10.1097/ BRS.0000000000002961
69. Brinjikji W, Diehn FE, Jarvik JG, et al. MRI findings of disc degeneration are more prevalent in adults with low back pain than in asymptomatic controls: a systematic review and me­ta-analysis. AJNR Am J Neuroradiol. 2015;36(12):2394-2399. doi: 10.3174/ajnr.A4498
70. Aprill C, Bogduk N. High-intensity zone: a diagnostic sign of painful lumbar disc on magnetic resonance imaging. Br J Radiol. 1992;65(773):361-369. doi: 10.1259/0007-1285-65­773-361
71. Tsuji H, Hirano N, Ohshima H, Ishihara H, Terahata N, Mo­toe T. Structural variation of the anterior and posterior anulus
Academy of Orthopaedic Physical erapy, APTA. For personal use only. No other uses without permission. © 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
41
fibrosus in the development of human lumbar intervertebral
https://t.me/med1917
disc. A risk factor for intervertebral disc rupture. Spine (Phila Pa
1976). 1993;18(2):204-210.
72.
Wang ZX, Hu YG. Factors associated with lumbar disc high-in­tensity zone (HIZ) on T2-weighted magnetic resonance image: a retrospective study of 3185 discs in 637 patients. J Orthop Surg Res. 2018;13(1):307. doi: 10.1186/s13018-018-1010-z Stadnik TW, Lee RR, Coen HL, Neirynck EC, Buisseret TS,
73. Osteaux MJ. Annular tears and disk herniation: prevalence and contrast enhancement on MR images in the absence of low back pain or sciatica. Radiology. 1998;206(1):49-55. doi:
10.1148/radiology.206.1.9423651
74. Liu C, Cai HX, Zhang JF, Ma JJ, Lu YJ, Fan SW. Quantita­tive estimation of the high-intensity zone in the lumbar spine: comparison between the symptomatic and asymptomatic population. Spine J. 2014;14(3):391-396. doi: 10.1016/j. spinee.2013.06.078
75. Carragee EJ, Paragioudakis SJ, Khurana S. 2000 Volvo Award winner in clinical studies: Lumbar high-intensity zone and dis­cography in subjects without low back problems. Spine (Phila Pa 1976). 2000;25(23):2987-2992. doi: 10.1097/00007632­200012010-00005
76.
WeiShaupt D, Zanetti M, Hodler J, Boos N. MR imaging of the lumbar spine: prevalence of intervertebral disk extrusion and sequestration, nerve root compression, end plate abnor­malities, and osteoarthritis of the facet joints in asymptomatic volunteers. Radiology. 1998;209(3):661-666. doi: 10.1148/ radiology.209.3.9844656 Campos M, Vial R, Castro J, Urrutia J. Prevalence of lum-
77. bar high-intensity zone: assessment using a screening tool independent of spinal symptoms. Acta Orthopaedica Belgica. 2019;85(1):47-53.
78. Fang C, Zhang W, Chen L, Li H. e correlation between the high-intensity zone on a T2-weighted MRI and positive outcomes of discography: a meta-analysis. J Orthop Surg Res. 2017;12(1):26. doi: 10.1186/s13018-017-0523-1
79. Waldenberg C, Hebelka H, Brisby H, Lagerstrand KM. Dif­ferences in IVD characteristics between low back pain patients and controls associated with HIZ as revealed with quantitative MRI. PLoS One. 2019;14(8):e0220952. doi: 10.1371/journal. pone.0220952
80. Horton WC, Daftari TK. Which disc as visualized by magnetic resonance imaging is actually a source of pain? A correla­tion between magnetic resonance imaging and discography. Spine. 1992;17(6 Suppl):S164-171. doi: 10.1097/00007632­199206001-00018
81. Petersen T, Laslett M, Juhl C. Clinical classification in low back pain: best-evidence diagnostic rules based on systematic reviews. BMC Musculoskelet Disord. 2017;18(1):188. doi: 10.1186/ s12891-017-1549-6 Murtagh FR. e importance of being earnest--about disk
82. nomenclature. AJNR Am J Neuroradiol. 2007;28(1):1-2.
83. Costello RF, Beall DP. Nomenclature and standard reporting terminology of intervertebral disk herniation. Magn Reson Imaging Clin N Am. 2007;15(2):167-174, v-vi. doi: 10.1016/j. mric.2006.12.001
84. Fardon DF, Williams AL, Dohring EJ, Murtagh FR, Gabriel Rothman SL, Sze GK. Lumbar disc nomenclature: version
2.0: recommendations of the combined task forces of the North American Spine Society, the American Society of Spine
Radiology, and the American Society of Neuroradiology. Spine (Phila Pa 1976). 2014;39(24):E1448-1465. doi: 10.1097/ BRS.0b013e3182a8866d Jensen MC, Brant-Zawadzki MN, Obuchowski N, Modic
85. MT, Malkasian D, Ross JS. Magnetic resonance imaging of the lumbar spine in people without back pain. New Engl J Med. 1994;331(2):69-73. doi: 10.1056/NEJM199407143310201
86.
Boden SD, Davis DO, Dina TS, Patronas NJ, Wiesel SW. Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation. J Bone Joint Surg Am. 1990;72(3):403-408. Kim SJ, Lee TH, Lim SM. Prevalence of disc degeneration in
87. asymptomatic korean subjects. Part 1: lumbar spine. J Korean Neurosurg Soc. 2013;53(1):31-38. doi: 10.3340/ jkns.2013.53.1.31
88.
Chiu CC, Chuang TY, Chang KH, Wu CH, Lin PW, Hsu WY. e probability of spontaneous regression of lumbar herniated disc: a systematic review. Clin Rehabil. 2015;29(2):184-195. doi: 10.1177/0269215514540919 Altun I, Yüksel KZ. Lumbar herniated disc: spontaneous
89. regression. Korean J Pain. 2017;30(1):44-50. doi: 10.3344/ kjp.2017.30.1.44
90.
Turk O, Antar V, Yaldiz C. Spontaneous regression of herni­ated nucleus pulposus: e clinical findings of 76 patients. Medicine (Baltimore). 2019;98(8):e14667. doi: 10.1097/ MD.0000000000014667 Dudli S, Fields AJ, Samartzis D, Karppinen J, Lotz JC. Pathobi-
91. ology of Modic changes. Eur Spine J. 2016;25(11):3723-3734. doi: 10.1007/s00586-016-4459-7
92.
Herlin C, Kjaer P, Espeland A, et al. Modic changes-eir associations with low back pain and activity limitation: A systematic literature review and meta-analysis. PLoS One. 2018;13(8):e0200677. doi: 10.1371/journal.pone.0200677
93. Teraguchi M, Yim R, Cheung JP, Samartzis D. e association of high-intensity zones on MRI and low back pain: a system­atic review. Scoliosis Spinal Disord. 2018 Oct 20;13:22. doi:
10.1186/s13013-018-0168-9
94. Wilson CA, Roffey DM, Chow D, Alkherayf F, Wai EK. A systematic review of preoperative predictors for postopera­tive clinical outcomes following lumbar discectomy. Spine J. 2016;16(11):1413-1422.
95. Laustsen AF, Bech-Azeddine R. Do Modic changes have an im­pact on clinical outcome in lumbar spine surgery? A systematic literature review. Eur Spine J. 2016;25(11):3735-3745. doi:
10.1016/j.spinee.2016.08.003 Macedo LG, Battié MC. e association between occupa-
96. tional loading and spine degeneration on imaging - a sys­tematic review and meta-analysis. BMC Musculoskelet Disord. 2019;20(1):489. doi: 10.1186/s12891-019-2835-2
97. Jensen RK, Leboeuf-Yde C. Is the presence of modic changes as­sociated with the outcomes of different treatments? A systematic critical review. BMC Musculoskelet Disord. 2011 Aug 10;12:183. doi: 10.1186/1471-2474-12-183
98. Annen M, Peterson C, Humphreys BK. Comparison of treat­ment outcomes in nonspecific low-back pain patients with and without Modic changes who receive chiropractic treatment. J Manipulative Physiol er. 2018;41(7):561-570. doi: 10.1016/j. jmpt.2018.01.008
99. Wong AYL, Parent EC, Dhillon SS, Prasad N, Samartzis D, Kawchuk GN. Differential patient responses to spinal ma-
42
Academy of Orthopaedic Physical erapy, APTA.
© 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
For personal use only. No other uses without permission.
nipulative therapy and their relation to spinal degeneration
https://t.me/med1917
and post-treatment changes in disc diffusion. Eur Spine J. 2019;28(2):259-269. doi: 10.1007/s00586-018-5851-2
100. Wu J, Huang J, Battié MC, Wang Y. Lifestyle and lifetime occupational exposures may not play a role in the pathogenesis of Modic changes on the lumbar spine MR images. Spine J. 2020;20(1):94-100. doi: 10.1016/j.spinee.2019.08.009 Kregel J, Meeus M, Malfliet A, et al. Structural and functional
101. brain abnormalities in chronic low back pain: A systematic review. Semin Arthritis Rheum. 2015;45(2):229-237. doi:
10.1016/j.semarthrit.2015.05.002
102.
Kurth F, Zilles K, Fox PT, Laird AR, Eickhoff SB. A link between the systems: functional differentiation and integra­tion within the human insula revealed by meta-analysis. Brain Structure Function. 2010;214(5-6):519-534. doi: 10.1007/ s00429-010-0255-z Lorenz J, Minoshima S, Casey KL. Keeping pain out of mind:
103. the role of the dorsolateral prefrontal cortex in pain modula­tion. Brain. 2003;126(Pt 5):1079-1091. doi: 10.1093/brain/ awg102
104.
Ng SK, Urquhart DM, Fitzgerald PB, Cicuttini FM, Hussain SM, Fitzgibbon BM. e Relationship between structural and functional brain changes and altered emotion and cognition in chronic low back pain brain changes: a systematic review of MRI and fMRI studies. Clin J Pain. 2018;34(3):237-261. doi:
10.1097/AJP.0000000000000534 Li T, Zhang S, Kurata J. Suppressed descending pain modulato-
105. ry and enhanced sensorimotor networks in patients with chron­ic low back pain. J Anesth. 2018;32(6):831-843. doi: 10.1007/ s00540-018-2561-1
106. Mansour ZM, Lepping RJ, Honea RA, et al. Structural brain imaging in people with low back pain. Spine (Phila Pa 1976). 2017;42(10):726-732. doi: 10.1097/BRS.0000000000001915
107. Dolman AJ, Loggia ML, Edwards RR, et al. Phenotype matters: the absence of a positive association between cortical thinning and chronic low back pain when controlling for salient clinical variables. Clin J Pain. 2014;30(10):839-845. doi: 10.1097/ AJP.0000000000000043
108.
Apkarian AV, Sosa Y, Sonty S, et al. Chronic back pain is associ­ated with decreased prefrontal and thalamic gray matter density. J Neurosci. 2004;24(46):10410-10415. doi: 10.1523/JNEURO­SCI.2541-04.2004 Seminowicz DA, Wideman TH, Naso L, et al. Effective treat-
109. ment of chronic low back pain in humans reverses abnormal brain anatomy and function. J Neurosci. 2011;31(20):7540-
7550. doi: 10.1523/JNEUROSCI.5280-10.2011
110.
Kim H, Mawla I, Lee J, et al. Reduced tactile acuity in chronic low back pain is linked with structural neuroplasticity in primary somatosensory cortex and is modulated by acupunc­ture therapy. Neuroimage. 2020;217:116899. doi: 10.1016/j. neuroimage.2020.116899 Perreault M, Katerelos TE, Sabourin S, Leichner P, Desmarais
111. J. Information as a distinct dimension for satisfaction assess­ment of outpatient psychiatric services. Int J Health Care Qual Assur Inc Leadersh Health Serv. 2001;14(2-3):111-120. doi:
10.1108/09526860110391586
112. Yang Q, Beatty M. A meta-analytic review of health informa­tion credibility: Belief in physicians or belief in peers? Health Inf Manage. 2016;45(2):80-89. doi: 10.1177/1833358316639432
113.
O’Sullivan PB, Caneiro JP, O’Sullivan K, et al. Back to basics: 10 facts every person should know about back pain. Br J Sports Med. 2020;54(12):698-699. doi: 10.1136/ bjsports-2019-101611 Deyo R, Weinstein J. Low back pain. N Engl J Med.
114. 2001;344(5):363-370. doi: 10.1056/NEJM200102013440508 Sung W, Abraham M, Plastaras C, Silfies SP. Trunk motor con-
115. trol deficits in acute and subacute low back pain are not associ­ated with pain or fear of movement. Spine J. 2015;15(8):1772-
1782. doi: 10.1016/j.spinee.2015.04.010
116.
Hodges PW, Richardson CA. Inefficient muscular stabilization of the lumbar spine associated with low back pain. A motor control evaluation of transversus abdominis. Spine (Phila Pa
1976). 1996;21(22):2640-2650. doi: 10.1097/00007632­199611150-00014
117. Hodges PW, Richardson CA. Altered trunk muscle recruitment in people with low back pain with upper limb movement at dif­ferent speeds. Arch Phys Med Rehabil. 1999;80(9):1005-1012. doi: 10.1016/s0003-9993(99)90052-7 Ferreira PH, Ferreira ML, Hodges PW. Changes in recruit-
118. ment of the abdominal muscles in people with low back pain: ultrasound measurement of muscle activity. Spine (Phila Pa 1976). 2004;29(22):2560-2566. doi: 10.1097/01. brs.0000144410.89182.f9
119.
Morris SL, Lay B, Allison GT. Transversus abdominis is part of a global not local muscle synergy during arm movement. Human Move Sci. 2013;32(5):1176-1185. doi: 10.1016/j. humov.2012.12.011 Davarian S, Maroufi N, Ebrahimi E, Parnianpour M, Farah-
120. mand F. Normal postural responses preceding shoulder flexion: co-activation or asymmetric activation of transverse abdom­inis? J Back Musculoskelet Rehabil. 2014;27(4):545-551. doi:
10.3233/BMR-140480
121. Mehta R, Cannella M, Henry SM, Smith S, Giszter S, Silfies SP. Trunk postural muscle timing is not compromised in low back pain patients clinically diagnosed with movement coordi­nation impairments. Motor Control. 2017;21(2):133-157. doi:
10.1123/mc.2015-0049
122.
Kjaer P, Bendix T, Sorensen JS, Korsholm L, Leboeuf-Yde C. Are MRI-defined fat infiltrations in the multifidus muscles associated with low back pain? BMC Med. 2007;5:2. doi:
10.1186/1741-7015-5-2 Beneck GJ, Kulig K. Multifidus atrophy is localized and
123. bilateral in active persons with chronic unilateral low back pain. Arch Phys Med Rehabil. 2012;93(2):300-306. doi: 10.1016/j. apmr.2011.09.017
124.
Jiang J, Wang H, Wang L, et al. Multifidus degeneration, a new risk factor for lumbar spinal stenosis: a case-control study. World Neurosurg. 2017;99:226-231. doi: 10.1016/j.wneu.2016.11.142
125. Shahidi B, Hubbard JC, Gibbons MC, et al. Lumbar multifidus muscle degenerates in individuals with chronic degenerative lumbar spine pathology. J Orthop Res. 2017;35(12):2700-2706. doi: 10.1002/jor.23597
126. Panjabi MM. e stabilizing system of the spine. Part I. Function, dysfunction, adaptation, and enhancement. J Spinal Disorders. 1992;5(4):383-389; discussion 397. doi:
10.1097/00002517-199212000-00001
127. Brumagne S, Cordo P, Lysens R, Verschueren S, Swinnen S. e role of paraspinal muscle spindles in lumbosacral position sense in individuals with and without low back pain. Spine
Academy of Orthopaedic Physical erapy, APTA. For personal use only. No other uses without permission. © 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
43
(Phila Pa 1976). 2000;25(8):989-994. doi: 10.1097/00007632-
https://t.me/med1917
200004150-00015 Newcomer KL, Laskowski ER, Yu B, Johnson JC, An KN.
128. Differences in repositioning error among patients with low back pain compared with control subjects. Spine (Phila Pa 1976). 2000;25(19):2488-2493. doi: 10.1097/00007632-200010010­00011 Hidalgo B, Gobert F, Bragard D, Detrembleur C. Effects of
129. proprioceptive disruption on lumbar spine repositioning error in a trunk forward bending task. J Back Musculoskelet Rehabil. 2013;26(4):381-387. doi: 10.3233/BMR-130396
130.
Pickar JG, Wheeler JD. Response of muscle proprioceptors to spinal manipulative-like loads in the anesthetized cat. J Manipulative Physiol er. 2001;24(1):2-11. doi: 10.1067/ mmt.2001.112017
131.
Hildebrandt M, Fankhauser G, Meichtry A, Luomajoki H. Correlation between lumbar dysfunction and fat infiltration in
Musculoskelet Disord. 2017;18(1):12. doi: 10.1186/s12891-016­1376-1 Hodges PW, Tucker K. Moving differently in pain: a new
132. theory to explain the adaptation to pain. Pain. 2011;152(3 Suppl):S90-98. doi: 10.1016/j.pain.2010.10.020 van Dieën JH, Flor H, Hodges PW. Low-back pain patients
133. learn to adapt motor behavior with adverse secondary con­sequences. Exerc Sport Sci Rev. 2017;45(4):223-229. doi:
10.1249/JES.0000000000000121
134. Arendt-Nielsen L, Brennum J, Sindrup S, Bak P. Electrophysio­logical and psychophysical quantification of temporal summa­tion in the human nociceptive system. Eur J Appl Physiol Occup Physiol. 1994;68(3):266-273. doi: 10.1007/BF00376776
135.
Roussel N, Nijs J, Meeus M, Mylius V, Fayt C, Oostendorp R. Central sensitization and altered central pain process­ing in chronic low back pain: fact or myth? Clin J Pain. 2013;29(7):625-638. doi: 10.1097/AJP.0b013e31826f9a71
136. den Bandt HL, Paulis WD, Beckwée D, Ickmans K, Nijs J, Voogt L. Pain mechanisms in low back pain: a systematic review with meta-analysis of mechanical quantitative sensory testing outcomes in people with nonspecific low back pain. J Orthop Sports Phys er. 2019;49(10):698-715. doi: 10.2519/ jospt.2019.8876 Hubscher M, Moloney N, Leaver A, Rebbeck T, McAuley JH,
137. Refshauge KM. Relationship between quantitative sensory test­ing and pain or disability in people with spinal pain-a systemat­ic review and meta-analysis. Pain. 2013;154(9):1497-1504. doi:
10.1016/j.pain.2013.05.031
138.
Diers M, Koeppe C, Diesch E, et al. Central processing of acute muscle pain in chronic low back pain patients: an EEG mapping study. J Clin Neurophysiol. 2007;24(1):76-83. doi:
10.1097/01.wnp.0000241093.00844.0e
139. Baliki MN, Geha PY, Apkarian AV, Chialvo DR. Beyond feel­ing: chronic pain hurts the brain, disrupting the default-mode network dynamics. J Neurosci. 2008;28(6):1398-1403. doi:
10.1523/JNEUROSCI.4123-07.2008
140. Tagliazucchi E, Balenzuela P, Fraiman D, Chialvo DR. Brain
resting state is disrupted in chronic back pain patients. Neurosci Lett. 2010;485(1):26-31. doi: 10.1016/j.neulet.2010.08.053
141. Kobayashi Y, Kurata J, Sekiguchi M, et al. Augmented cerebral activation by lumbar mechanical stimulus in chronic low back
pain patients. Spine. 2009;34(22):2431-2436. doi: 10.1097/ BRS.0b013e3181b1fb76
142. Giesecke T, Gracely R, Grant M, et al. Evidence of augmented central pain processing in idiopathic chronic low back pain. Arthritis Rheum. 2004;50(2):613-623. doi: 10.1002/art.20063
143.
Baliki MN, Chialvo DR, Geha PY, et al. Chronic pain and the emotional brain: specific brain activity associated with spontaneous fluctuations of intensity of chronic back pain. J Neurosci. 2006;26(47):12165-12173. doi: 10.1523/JNEUROS­CI.3576-06.2006
144. Baliki MN, Geha PY, Fields HL, Apkarian AV. Predicting value of pain and analgesia: nucleus accumbens response to nox­ious stimuli changes in the presence of chronic pain. Neuron. 2010;66(1):149-160. doi: 10.1016/j.neuron.2010.03.002 Bannister K, Dickenson AH. e plasticity of descend-
145. ing controls in pain: translational probing. J Physiol. 2017;595(13):4159-4166. doi: 10.1113/JP274165
146.
Le Bars D, Dickerson A, Besson J. Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat. Pain. 1979;6(3):283-304. doi: 10.1016/0304­3959(79)90049-6
147. Pud D, Granovsky Y, Yarnitsky D. e methodology of experimentally induced diffuse noxious inhibitory control (DNIC)-like effect in humans. Pain. 2009;144(1-2):16-19. doi:
10.1016/j.pain.2009.02.015
148. Peters ML, Schmidt AJ, Van den Hout MA, Koopmans R, Slu­ijter ME. Chronic back pain, acute postoperative pain and the activation of diffuse noxious inhibitory controls (DNIC). Pain. 1992;50(2):177-187. doi: 10.1016/0304-3959(92)90159-9
149. Mlekusch S, Neziri AY, Limacher A, Jüni P, Arendt-Nielsen L, Curatolo M. Conditioned pain modulation in patients with acute and chronic low back pain. Clin J Pain. 2016;32(2):116-
121. doi: 10.1097/AJP.0000000000000238 McPhee ME, Vaegter HB, Graven-Nielsen T. Alterations in
150. pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis. Pain. 2020;161(3):464-475. doi: 10.1097/j.pain.0000000000001737
151. Plow EB, Arora P, Pline MA, Binenstock MT, Carey JR. Within-limb somatotopy in primary motor cortex--revealed using fMRI. Cortex. 2010;46(3):310-321. doi: 10.1016/j. cortex.2009.02.024
152. Asavasopon S, Rana M, Kirages DJ, et al. Cortical activation associated with muscle synergies of the human male pelvic floor. J Neurosci. 2014;34(41):13811-13818. doi: 10.1523/ JNEUROSCI.2073-14.2014
153. Saby JN, Meltzoff AN, Marshall PJ. Neural body maps in human infants: Somatotopic responses to tactile stimulation in 7-month-olds. Neuroimage. 2015;118:74-78. doi: 10.1016/j. neuroimage.2015.05.097
154. Tsao H, Danneels LA, Hodges PW. ISSLS prize winner: Smudging the motor brain in young adults with recurrent low back pain. Spine (Phila Pa 1976). 2011;36(21):1721-1727. doi:
10.1097/BRS.0b013e31821c4267
155. Schabrun SM, Elgueta-Cancino EL, Hodges PW. Smudging of the motor cortex is related to the severity of low back pain. Spine (Phila Pa 1976). 2017;42(15):1172-1178. doi: 10.1097/ BRS.0000000000000938
156. Hotz-Boendermaker S, Marcar VL, Meier ML, Boender­maker B, Humphreys BK. Reorganization in secondary somatosensory cortex in chronic low back pain patients.
44
Academy of Orthopaedic Physical erapy, APTA.
© 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
For personal use only. No other uses without permission.
Spine (Phila Pa 1976). 2016;41(11):E667-673. doi: 10.1097/
https://t.me/med1917
BRS.0000000000001348 Tsao H, Galea MP, Hodges PW. Reorganization of the motor
157. cortex is associated with postural control deficits in recur­rent low back pain. Brain. 2008;131(Pt 8):2161-2171. doi:
10.1093/brain/awn154
158.
Martini L, Hoffmann F. Comorbidity of chronic back pain and depression in Germany: Results from the GEDA study, 2009 and 2010. Z Evid Fortbild Qual Gesundheitswes. 2018;137- 138:62-68. doi: 10.1016/j.zefq.2018.10.003 Stubbs B, Vancampfort D, Veronese N, et al. Depression and
159. pain: primary data and meta-analysis among 237
952 people across 47 low- and middle-income countries. Psychol Med. 2017;47(16):2906-2917. doi: 10.1017/S0033291717001477
160. Sullivan MJ, Reesor K, Mikail S, Fisher R. e treatment of depression in chronic low back pain: review and recom­mendations. Pain. 1992;50(1):5-13. doi: 10.1016/0304­3959(92)90107-M Pinheiro MB, Ferreira ML, Refshauge K, et al. Symptoms of
161. depression as a prognostic factor for low back pain: a sys­tematic review. Spine J. 2016;16(1):105-116. doi: 10.1016/j. spinee.2015.10.037
162.
Oliveira DS, Vélia Ferreira Mendonça L, Sofia Monteiro Sampaio R, Manuel Pereira Dias de Castro-Lopes J, Ribeiro de Azevedo LF. e impact of anxiety and depression on the outcomes of chronic low back pain multidisciplinary pain man­agement-a multicenter prospective cohort study in pain clinics with one-year follow-up. Pain Med. 2019;20(4):736-746. doi:
10.1093/pm/pny128
163. Bech A, Steer R, Brown G. Beck Depression Inventory. 2nd ed: manual. e Psychological Corporation. 1996;4:561-571.
164.
Jarvik JG, Hollingworth W, Heagerty PJ, Haynor DR, Boyko EJ, Deyo RA. ree-year incidence of low back pain in an initially asymptomatic cohort: clinical and imaging risk factors. Spine (Phila Pa 1976). 2005;30(13):1541-1548; discussion
1549. doi: 10.1097/01.brs.0000167536.60002.87 Quartana PJ, Campbell CM, Edwards RR. Pain catastrophiz-
165. ing: a critical review. Expert Rev Neurother. 2009;9(5):745-758. doi: 10.1586/ern.09.34
166. Sullivan MB, Bishop SR; Pivik J. e Pain Catastrophizing Scale: development and validation. Psychological Assessment. 1995;7(4):524-532. doi.org/10.1037/1040-3590.7.4.524 Wertli MM, Eugster R, Held U, Steurer J, Kofmehl R,
167. Weiser S. Catastrophizing-a prognostic factor for outcome in patients with low back pain: a systematic review. Spine J. 2014;14(11):2639-2657. doi: 10.1016/j.spinee.2014.03.003
168.
Alhowimel A, AlOtaibi M, Radford K, Coulson N. Psy­chosocial factors associated with change in pain and dis­ability outcomes in chronic low back pain patients treated by physiotherapist: A systematic review. SAGE Open Med. 2018;6:2050312118757387. doi: 10.1177/2050312118757387 Hubbard CS, Khan SA, Keaser ML, Mathur VA, Goyal M,
169. Seminowicz DA. Altered brain structure and function correlate with disease severity and pain catastrophizing in migraine patients. eNeuro. 2014;1(1):e20.14. doi: 10.1523/ ENEURO.0006-14.2014
170. Coronado RA, George SZ, Devin CJ, Wegener ST, Archer KR. Pain Sensitivity and pain catastrophizing are associated with persistent pain and disability after lumbar spine surgery. Arch
Phys Med Rehabil. 2015;96(10):1763-1770. doi: 10.1016/j. apmr.2015.06.003
171. Severeijns R, Vlaeyen J, Vvan den Hout M, Weber W. Pain catastrophizing predicts pain intensity, disability, and psycho­logical distress independent of the level of physical impairment. Clin J Pain. 2001;17(2):165-172. doi: 10.1097/00002508­200106000-00009 Kovacs FM, Seco J, Royuela A, Peña A, Muriel A. e correla-
172. tion between pain, catastrophizing, and disability in subacute and chronic low back pain: a study in the routine clinical practice of the Spanish National Health Service. Spine (Phila Pa 1976). 2011;36(4):339-345. doi: 10.1097/BRS. 0b013e3181cfba29
173.
Meints SM, Mawla I, Napadow V, et al. e relationship between catastrophizing and altered pain sensitivity in patients with chronic low-back pain. Pain. 2019;160(4):833-843. doi:
10.1097/j.pain.0000000000001461
174.
Vlaeyen J, Kole-Snijders AM, Boeren RG, Van Eek H. Fear of movement/(re) injury in chronic low back pain and its relation to behavioral performance. Pain. 1995;62(3):363-372. doi:
10.1016/0304-3959(94)00279-N Crombez G, Eccleston C, Van Damme S, Vlaeyen JW,
175. Karoly P. Fear-avoidance model of chronic pain: the next generation. Clin J Pain. 2012;28(6):475-483. doi: 10.1097/ AJP.0b013e3182385392
176. Vlaeyen JW, Linton SJ. Fear-avoidance and its consequenc­es in chronic musculoskeletal pain: a state of the art. Pain. 2000;85(3):317-332. doi: 10.1016/S0304-3959(99)00242-0
177. Crombez G, Vlaeyen J, Heuts P, Lysens R. Pain-related fear is more disabling than pain itself: evidence on the role of pain-re­lated fear in chronic back pain disability. Pain. 1999;80:329-
339. doi: 10.1016/s0304-3959(98)00229-2
178. Waddell G, Newton M, Henderson I, Somerville D, Main CJ. A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain. 1993;52(2):157-168. doi: 10.1016/0304-3959(93)90127­B
179.
Trinderup JS, Fisker A, Juhl CB, Petersen T. Fear avoidance beliefs as a predictor for long-term sick leave, disability and pain in patients with chronic low back pain. BMC Musculoskelet Disord. 2018;19(1):431. doi: 10.1186/s12891-018-2351-9
180. Alamam DM, Moloney N, Leaver A, Alsobayel HI, Mackey MG. Multidimensional prognostic factors for chronic low back pain-related disability: a longitudinal study in a Saudi population. Spine J. 2019;19(9):1548-1558. doi: 10.1016/j. spinee.2019.05.010 Wertli MM, Rasmussen-Barr E, Weiser S, Bachmann LM,
181. Brunner F. e role of fear avoidance beliefs as a prognostic factor for outcome in patients with nonspecific low back pain: a systematic review. Spine J. 2014;14(5):816-836.e814. doi:
10.1016/j.spinee.2013.09.036
182. Parreira P, Maher CG, Steffens D, Hancock MJ, Ferreira ML. Risk factors for low back pain and sciatica: an umbrel­la review. Spine J. 2018;18(9):1715-1721. doi: 10.1016/j. spinee.2018.05.018
183. Fink G. Fink G. Stress, Definitions, Mechanisms, and Effects Outlined: Lessons from Anxiety. In: Fink G, ed. Stress: Concepts,
Cognition, Emotion, and Behavior, Volume 1 of the Handbook of Stress Series. Elsevier Inc., 2016: 3-11.
Academy of Orthopaedic Physical erapy, APTA. For personal use only. No other uses without permission. © 2021 Academy of Orthopaedic Physical erapy, APTA, Inc. All rights reserved.
45
184. Hannibal KE, Bishop MD. Chronic stress, cortisol dysfunction,
https://t.me/med1917
and pain: a psychoneuroendocrine rationale for stress manage­ment in pain rehabilitation. Phys er. 2014;94(12):1816-1825. doi: 10.2522/ptj.20130597
185.
Ashdown-Franks G, Firth J, Carney R, et al. Exercise as Med­icine for mental and substance use disorders: a meta-review of the benefits for neuropsychiatric and cognitive outcomes. Sports Med. 2020;50(1):151-170. doi: 10.1007/s40279-019-01187-6 Fritz JM, Cleland JA, Speckman M, Brennan GP, Hunter SJ.
186. Physical therapy for acute low back pain: associations with subsequent healthcare costs. Spine (Phila Pa 1976). 2008; 33(16):1800-1805. doi: 10.1097/BRS.0b013e31817bd853
187.
Fritz JM, Kim M, Magel JS, Asche CV. Cost-effectiveness of primary care management with or without early physical ther­apy for acute low back pain: economic evaluation of a random­ized clinical trial. Spine (Phila Pa 1976). 2017;42(5):285-290. doi: 10.1097/BRS.0000000000001729 Young Casey C, Greenberg MA, Nicassio PM, Harpin RE,
188. Hubbard D. Transition from acute to chronic pain and disabil­ity: a model including cognitive, affective, and trauma factors. Pain. 2008;134(1-2):69-79. doi: 10.1016/j.pain.2007.03.032
189. Baliki MN, Petre B, Torbey S, et al. Corticostriatal functional connectivity predicts transition to chronic back pain. Nature Neuroscience. 2012;15(8):1117-1119. doi: 10.1038/nn.3153
190. Müller M, Curatolo M, Limacher A, et al. Predicting transition from acute to chronic low back pain with quantitative sensory tests-A prospective cohort study in the primary care setting. Eur J Pain. 2019;23(5):894-907. doi: 10.1002/ejp.1356
191. Klyne DM, Moseley GL, Sterling M, Barbe MF, Hodges PW. Are signs of central sensitization in acute low back pain a precursor to poor outcome? J Pain. 2019;20(8):994-1009. doi:
10.1016/j.jpain.2019.03.001
192. Hill JC, Whitehurst DG, Lewis M, et al. Comparison of strat­ified primary care management for low back pain with current best practice (STarT Back): a randomised controlled trial. Lancet (London, England). 2011;378(9802):1560-1571. doi:
10.1016/S0140-6736(11)60937-9 Main CJ, Sowden G, Hill JC, Watson PJ, Hay EM. Integrating
193. physical and psychological approaches to treatment in low back pain: the development and content of the STarT Back trial’s ‘high-risk’ intervention (StarT Back; ISRCTN 37113406). Physiotherapy. 2012;98(2):110-116. doi: 10.1016/j.physio.
2011.03.003
194.
Katzan IL, ompson NR, George SZ, Passek S, Frost F, Stilphen M. e use of STarT back screening tool to predict functional disability outcomes in patients receiving physical therapy for low back pain. Spine J. 2019;19(4):645-654. doi:
10.1016/j.spinee.2018.10.002
195. Fritz JM, Beneciuk JM, George SZ. Relationship between cat­egorization with the STarT Back Screening Tool and prognosis for people receiving physical therapy for low back pain. Phys er. 2011;91(5):722-732. doi: 10.2522/ptj.20100109
196. Linton SJ, Halldén K. Can we screen for problematic back pain? A screening questionnaire for predicting outcome in acute and subacute back pain. Clin J Pain. 1998;14(3):209-215. doi:
10.1097/00002508-199809000-00007
197. Lheureux A, Berquin A. Comparison between the STarT Back Screening Tool and the Örebro Musculoskeletal Pain Screening Questionnaire: Which tool for what purpose? A semi-system-
atic review. Ann Phys Rehabil Med. 2019;62(3):178-188. doi:
10.1016/j.rehab.2018.09.007
198. Pauli J, Starkweather A, Robins JL. Screening tools to predict the development of chronic low back pain: an integrative review of the literature. Pain Med. 2019;20(9):1651-1677. doi:
10.1093/pm/pny178 Karran EL, McAuley JH, Traeger AC, et al. Can screening
199. instruments accurately determine poor outcome risk in adults with recent onset low back pain? A systematic review and me­ta-analysis. BMC Med. 2017;15(1):13. doi: 10.1186/s12916­016-0774-4
200. Oliveira CB, Maher CG, Pinto RZ, et al. Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview. Eur Spine J. 2018;27(11):2791-2803. doi: 10.1007/s00586-018-5673-2
201.
Slade SC, Kent P, Patel S, Bucknall T, Buchbinder R. Barriers to primary care clinician adherence to clinical guidelines for the management of low back pain: a systematic review and meta­synthesis of qualitative studies. Clin J Pain. 2016;32(9):800-
816. doi: 10.1097/AJP.0000000000000324
202. Fritz JM, Cleland JA, Brennan GP. Does adherence to the guideline recommendation for active treatments improve the quality of care for patients with acute low back pain delivered by physical therapists? Med Care. 2007;45(10):973-980. doi:
10.1097/MLR.0b013e318070c6cd
203. Feuerstein M, Hartzell M, Rogers HL, Marcus SC. Evi­dence-based practice for acute low back pain in primary care: patient outcomes and cost of care. Pain. 2006;124(1-2):140-
149. doi: 10.1016/j.pain.2006.04.007
204. Koes BW, Van Tulder M, Lin C-WC, Macedo LG, McAuley J, Maher C. An updated overview of clinical guidelines for the management of non-specific low back pain in primary care. Eur Spine J. 2010;19(12):2075-2094. doi: 10.1007/s00586-010­1502-y
205. Flynn T, Fritz J, Whitman J, et al. A clinical prediction rule for classifying patients with low back pain who demonstrate short-term improvement with spinal manipulation. Spine (Phila Pa 1976). 2002;27(24):2835-2843. doi: 10.1097/00007632­200212150-00021
206. Lebec MT, Jogodka CE. e physical therapist as a musculo­skeletal specialist in the emergency department. J Orthop Sports Phys er. 2009;39(3):221-229. doi: 10.2519/jospt.2009.2857 Boissonnault WG, Ross MD. Physical therapists referring
207. patients to physicians: a review of case reports and series. J Orthop Sports Phys er. 2012;42(5):446-454. doi: 10.2519/ jospt.2012.3890
208.
Mintken PE, Pascoe SC, Barsch AK, Cleland JA. Direct Access to Physical erapy Services Is Safe in a University Student Health Center Setting. J Allied Health. 2015;44(3):164-168.
209. Moore JH, McMillian DJ, Rosenthal MD, Weishaar MD. Risk determination for patients with direct access to physical therapy in military health care facilities. J Orthop Sports Phys er. 2005;35(10):674-678. doi: 10.2519/jospt.2005.35.10.674
210. Leerar PJ, Boissonnault W, Domholdt E, Roddey T. Docu­mentation of red flags by physical therapists for patients with low back pain. J Man Manip er. 2007;15(1):42-49. doi:
10.1179/106698107791090105
211. George SZ, Beneciuk JM, Bialosky JE, et al. Development of a review-of-systems screening tool for orthopaedic physical therapists: results from the Optimal Screening for Prediction of
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