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H. Y. Zhao and C. Zhan
3.3 Endoscope Management
1. The distal end of the endoscope may reach a high temperature of 50–55 °C during use. When the endoscope controller is turned on, avoid contact with skin, tissues, cloth dress­ings, etc., to prevent skin burns.
2. When the endoscope lens is connected to the system and emits light, avoid looking directly at it.
3. When the endoscope is fogging, immerse the lens end in 50 °C warm water for 10 s (the temperature does not exceed 55°C, and the time does not exceed 15s).
4. Lay a sterile table to place the 3D endoscope camera separately, connect it to the endoscope controller 30 min in advance to preheat it, place it between the image processing plat­form and the end of the operating table, cover it with sterile towels, and leave the surround­ings empty to avoid pollution [4].
3.4 Endo Wrist Device
Management
1. According to the needs of specialist surgery and the usage habits of surgeons, the special equipment is congured as a package of spe­cialist surgery equipment. Instruments that are not commonly used or of variable fre­quency are sterilized separately for easy turn­over. EndoWrist instruments are programmed to be used a predetermined number of times. At the same time, attention should be given to the limitation of the maximum number of sterilizations of the instruments to avoid the possibility of not being used after sterilization [4].
2. Establish equipment use les to record equip­ment name, use date, use status, repair appli­cation, and other information for easy traceability.
3. Disposal after use: When cleaning the instru­ment during the operation, the scrub nurse uses moist gauze to wipe off the blood on the tip and surface of the instrument. During the operation, the tip of the instrument was kept free of blood scabs and tissue attachment.
After the operation, the instrument should be pre- treated in time and placed properly for transportation. The scrub nurse and the nurse in the supply room handed over face-to-face and handed over detailed information on the instrument such as the name, quantity, use sta­tus, and completeness. After sterilization is completed, the instruments are placed in a dedicated rack for storage [5].
3.5 Intraoperative Control andInstrument Arm Management
According to the age of the child, the pneumo­peritoneum pressure is maintained at 6–10mmHg, the ow rate is 2–4L/min, and the single-bipolar coagulation is maintained at 15–20. Children’s abdomen operation space is limited, and the distance between the holes is closer than that of adults [6]. To ensure the maxi­mum reach and minimum arm interference, the instrument arms should be arranged in parallel to maintain a punch distance of the mechanical arms, and attention should be given to the operat­ing conditions to avoid equipment collisions. When replacing the operating forceps, ensure that the front joints remain straight to prevent shifting of the tip of the operating forceps and damaging the tissue when the operating forceps enter for the second time. At the same time, atten­tion should be given to the gap between the child and the distance between the robotic arm and the child’s body to avoid squeezing. After the opera­tion, remove the robotic arm, remove the sterile protective cover, and retract the robotic arm to the smallest extent [7].
3.6 Personnel Management andTraining
3.6.1 Da Vinci Operating Room Personnel Management
Strictly controlling the entry and exit of person­nel, except for the surgeon, anesthesiologist, and nurse of this surgery, the rest of the staff are not
3 Robotic Operating Room Conguration
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allowed to enter the robot operating room to visit. The instrument is hung with eye-catching signs to avoid accidental damage or collisions caused by unqualied personnel [1].
3.6.2 Establish da Vinci Surgical Medical Team
The da Vinci robotic surgery medical team was established before the operation, and nurses who had rich experience in specialist open surgery and procient in cooperation with laparoscopic surgery were selected to participate in the profes­sional training of the da Vinci robotic surgery system [8]. Before the operation, the team con­ducts preoperative simulation training, sets up various simulation scenes of robotic surgery, and repeats the practice, so that the nurses can achieve the team skills required for the work, and obtain professional certicates after the assessment [9].
3.6.3 Nurse Training
The da Vinci Surgical Nursing Specialist Group, which is jointly trained by nurses with profes­sional certicates and equipment engineers, was established to provide standardized and staged training for new nurses in the specialist group. Establish a training package including theoretical training, operational training, and simulation training, and modularize the training content according to the training period [10]. The train­ing content includes the knowledge of the robotic surgery system, which includes the performance of robotic surgery equipment, use procedures, operating methods, equipment names, uses, dis­assembly and cleaning, installation methods, daily maintenance, fault identication and pre­liminary. After completing all the content of the training package, the theory and operation assess­ment will be carried out, and then the next stage of simulation training can be entered after pass­ing the assessment. Simulation training is mainly to simulate the operation site, use similar equip­ment to increase its realism, and simulate many special situations that may occur during the
operation, which helps to improve the learning effect. Its practice content includes preoperative preparation, space layout, placement of the surgi­cal position, layout of the surgical hole, and placement of the bedside arm system. Only after completing all training content and passing the assessment can the nurse serve as a robotic sur­gery nurse. Finish the special operation coopera­tion manual used as daily training, including pathophysiology, article preparation, anesthesia methods, surgical positions, surgical platform paths, surgical procedures, precautions, and per­sonnel station maps [11].
3.7 Position Placement ofPediatric Robotic Surgery
1. Supine position: When the newborn is placed
in the posture, the overall body of the child should be raised by 10–15cm to increase the operating space of the robotic arm and avoid collisions between the robotic arm and the operating table.
(a) The child is placed in the supine position
with the head high, and the restraint belt is used to properly x the child, paste a lm sticker on the bone carina position bone of the child, place a silicone head ring under the head with cloth glue, and place a home-made water bag on the body with gloves on the limbs to prevent pres­sure ulcers. Properly arrange venous access, urinary catheters, zinc wire, etc., to prevent skin damage. It is suitable for the radical treatment of choledochal cysts, malrotation of the intestine, circu­lar pancreas, etc.
(b) The child is placed in the supine position
with the head low, the chest is lined with cotton pads and xed with cloth tape, shoulder pads are placed under the shoul­ders on both sides to prevent the patient from sliding down when the head is low and the feet are high or the patient’s posi­tion changes or accidents, placed under the head circle, the limbs are put into the water bag, and the lower limbs are xed
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with restraint straps. For urology patients, the hips are raised, the head is lowered in the supine position, and the knees are xed with cloth glue lined with cotton pads. It is suitable for anal atresia, mega­colon, ovarian cysts, vesicoureteral replantation, prostate cysts, etc.
2. Lateral position: (a) General thoracic surgery: The child is
lying on the contralateral side at 90°, with a head circle under the head, and a semi­circular soft cushion under the armpit to ensure that the gap between the side ribs of the patient is enlarged. The surgical site is exposed and the patient’s blood vessels and nerves are not compressed. In addition, place two U-shaped silicone pads was placed on the abdomen and back to x the child. The upper limb of the contralateral side is stretched out 90°, and the restraint belt is xed stably. The iliac area is reinforced with cloth glue. A soft pillow was placed between the lower limbs, straightening the lower limbs of the contralateral side, and exing the lower limbs of the affected side 90°. Water bags were placed between the feet. Suitability for lobectomy, mediastinal tumor, PDA ligation, etc [12].
(b) Urology: The child is lying on the contra-
lateral side at 60°, close to the bedside of the contralateral side, expanding the operating space of the robotic arm. The head ring is placed under the head, and a U-shaped silicone was placed on the back for xation with wide tape. A soft pillow was placed between the lower limbs, the lower limb of the contralateral side was straightened, the lower limb of the affected side was extended, and water bags were placed on the feet. Attentions should be given to the use of soft pads to
protect the skin of the patient’s vulnerable parts and keep the joints in a functional position. Suitability for renal pelvic ure­teral anastomosis, nephrectomy, adrenal tumors, and etc.
References
1. Zeng J. Design of the compound operating room with da Vinic robotic surgical system. China Medical Devices. 2016;31:121–3. in Chinese)
2. Giedelman C, Covas Moschovas M, Bhat S, et al. Establishing a successful robotic surgery program and improving operating room efciency: literature review and our experience report. J Robot Surg. 2021;15:435–42.
3. Lenihan JP Jr. How to set up a robotic-assisted laparo­scopic surgery center and training of staff. Best Pract Res Clin Obstet Gynaecol. 2017;45:19–31.
4. Larkins K, Mohamed JE, Mohan H, et al. How I Do It: Structured Narration for Cognitive Simulation­based Training in Robotic Surgery. J Surg Educ. 2023;80:624–8.
5. Jin Y, Zhang Y, Cai D, et al. Robot-Assisted Resection of Intestinal Duplication in Children. J Laparoendosc Adv Surg Tech A Part. 2022;32:1288–92.
6. Suo J, Hua R, Li N, et al. Cleaning and sterilization management of Da Vinci robot surgical instruments. Chinese J Disinfect. 2017;34:97–9.
7. Zhang H, Zeng Z, Cheng G, et al. Scientic manage­ment of the introduction of Da Vinci surgical robot into the use process. Beijing Biomedical Engineering. 2021;40:101–4.
8. Wu K, Zhang X. Application value of specialist group management in Da Vinci robot surgical instrument management. Medical Equipment. 2019;32:61–2.
9. Wei A, Li S, Pei H, et al. Application of ne manage­ment in Da Vinci robot surgical instrument manage­ment. J Modern Med Health. 2021;37:345–7.
10. Yu X, He M. Application of modular training model in coordination training for robotic surgery. Chinese J Robot Surg. 2022;3:217–23.
11. Shen X, Shi Z, Zhou Y, Yang J. Training of operat­ing room nurses over Da Vinci robot surgery based on checklist management. J Nurses Sci. 2022,37:34–6.
12. Tan B, Guo D, Tang L, et al. A comparative study of two kinds of posture placement by robot-assisted laparscopic radical prostatectomy. J Nurses Train. 2019;34:1043–5.
Pediatric Anesthesia forRobotic
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Surgery inChildren
JinjinHuang andYaoqinHu
4
Along with the rapid development of minimally invasive techniques, laparoscopy and thoracos­copy have become increasingly mature and are widely used in pediatric surgeries. Robotic sur­gery is the result of transformation in the mini­mally invasive surgical evolution [1]. Currently, the use of robotic platforms is widely accepted in many adult surgeries, especially urologic and gynecologic operations. The use of robotic sur­gery in pediatric patients is almost a decade later than in adults. Due to the limitations of equip­ment and technology, the application of robotic surgery in pediatrics lags behind that in adults. The advantages of robotic-assisted surgery (RAS) include smaller surgical incisions, improved precision, improved accuracy of the movements, less pain, and shorter hospital stays. The limitations of RAS may be the size of robot, the size of the patients, the cost, and so on. Therefore, all these factors may result in more complicated anesthetic management, particu­larly in younger children, such as neonates and infants. It is necessary to acquire prociency in the pathological and physiological changes asso-
ciated with pneumoperitoneum/pneumothorax, and be aware of the potential complications, so that we can provide safer and more effective anesthesia for pediatric patients undergoing robotic surgery. In addition, we should pay more attention to the inuence of patients’ position, lengths of operating time, loss of water, and so on (Fig. 4.1).
Fig. 4.1 Robot arm
J. Huang (*) · Y. Hu Department of Anaesthesiology, Children’s Hospital of Zhejiang University School of Medicine, Hangzhou, China e-mail: 6196008@zju.edu.cn; huyaoqin@zju.edu.cn
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023 Q. Shu (ed.), Pediatric Robotic Surgery, https://doi.org/10.1007/978-981-19-9693-1_4
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4.1 Robotic-Assisted Thoracoscopic Surgery
Robotic approaches have been used in many chest surgeries, including surgeries for congeni­tal diaphragmatic hernia, esophageal atresia, mediastinal cysts, diaphragmatic hernia, pulmo­nary lobectomy, esophageal cysts, and patent ductus arteriosus [26], with outstanding short­term outcomes. The concerns and key points of anesthesia were have changed equally since the development of technology. Compared with min­imally invasive surgery performed in other regions of the body, robotic-assisted thoraco­scopic surgery (RATS) is full of different chal­lenges. Specic anesthetic considerations for RATS includes the size of the robotic surgery device, which may limit the ability of anesthesi­ologist to access the patients, the patient posi­tions, and the absorption of CO2, which insufates in the thorax [7].
RATS may require the anesthetist to use the one- lung ventilation (OLV) technique to provide satisfactory visualization for surgeon. The lungs of infants are softer and easier to compress than those of adults. Moreover, the residual volume is larger and nearly equal to the functional residual capacity (FRC) in young children. Therefore, if the healthy lung is only ventilated, even in tidal breathing, lung compliance will decrease, and air­way closure will increase. For the pediatric popu­lation, the intercostal space and thoracic cavity are much smaller than those in adults, and lung isolation techniques are also not as mature as
those in adults. Before the robot is docked, bron­choberscope should be used to conrm the opti­mal position of the endotracheal tube. During the period of one- lung ventilation, pressure-con­trolled ventilation may provide superior serum oxygen tension and reduced peak airway pres­sures compared rather than volume-controlled ventilation [8].
Patient positioning plays an important role in the surgery. The position of RATS is lateral, simi­lar to the position of VATS, which limits the abil­ity of anesthetist to access to the patient’s arms and face. Therefore, the anesthesiology team should ensure that patients are visible and acces­sible. Additionally, robotic surgery has the risk that robotic arms may injure the patients, with additional potential for facial injuries [9], and we should check patients’ facial frequently. Infant has small thoracic size. During RATS, the hydro­static pressure gradient between dependent and nondependent lungs will decrease, which will inhibit hypoxic pulmonary vasoconstriction. Therefore, infants in the lateral position during one-lung ventilation(OLV) will be more suscep­tible to hypoxia [10].
The surgeon insufates CO2 into the thorax to obtain a wider visualization. However, systemic absorption of carbon dioxide(CO2), which insuf­ates into the intrapleural cavity, may lead to hypercarbia [11]. The shift of intrathoracic struc­tures will lead to hemodynamic effects. Therefore, maintain the ow rates and pressure as low as possible when infusing carbon dioxide into the chest (Fig. 4.2) [12].
d
4 Pediatric Anesthesia forRobotic Surgery inChildren
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a
Fig. 4.2 The child patient needs to undergo single-lung ventilation. (a) ber bronchoscopy view of the tracheal bifurcation and carina; (b) ber bronchoscopy left main
b
4.2 Robotic-Assisted Urologic Surgery
Pediatric urological surgery is one of the most common surgeries that employs robotic assis­tance in children. Pyeloplasty, surgery for treat­ing vesicouretric reux, nephrectomy, and heminephrectomy are the most commonly per­formed operations. The concerns about anesthe­sia in robotic-assisted urologic surgery are patient positioning, pathophysiological changes in the pneumoperitoneum, and absorption of CO2. In general, patients with congenital mal­formation of the urogenital system often undergo minimally invasive surgery. Those patients are always associated with heart mal-
c
bronchus occlusion procedure; (c) image of trachea bifur­cation under beroptic bronchoscope; (d) ventilator parameters during sing
formations [13]. Therefore urological condi­tions are always a signal to rule out congenital heart disease. Those patients concerns about renal insufciency, anemia, electrolyte imbal­ance, metabolic problems, and hypertension. In pediatric patients, a pneumoperitoneum pres­sure of 4–12mmHg is usually enough to explore the surgical area and provide an adequate surgi­cal eld of vision, because prepubertal children have softer abdominal walls and smaller perito­neal cavities than adults [14]. In addition, because of the increasing intraperitoneal pres­sure, the diaphragm will be elevated. Therefore, the functional residual capacity and lung com­pliance will decline, airway resistance and physiological dead space will increase, and V/Q will mismatch [13].
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Position has different effects on the circula­tory system, including cardiac output and blood pressure. The head-up position will reduce venous return of the heart blood volume and car­diac lling pressure. Additionally, some urologi­cal surgeries require lithotomy, in the lateral or prone position, which will result in potential nerve injuries. In addition, the steep Trendelenburg position will reduce lung compliance and induce inspiratory pressure increases, which increase the risk of barotrauma in patients.
In several cystoscopy and prostate surgeries that require the use of irrigation solution, it may be difcult to estimate blood loss and increase the risk of a reduction in body temperature. Children have a larger body surface area to mass ratio and thinner subcutaneous fat, which will make them more prone to lose heat. We can use warming blanket, infusion warming, and forced air warmers to avoid hypothermia. The insufng uid should be warmed, and the ow velocity should be less than 2L/min [15].
4.3 Robotic-Assisted General
Surgery
The applications of robotic-assisted general sur­gery include colectomy [16], fundoplication, and so on. RAS(robotic-assisted surgery) requires carbon dioxide insufation into the abdomen to provide effective visualization. Meanwhile some patients may need a reverse or steep Trendelenburg position.
The pneumoperitoneum will increase intra­abdominal pressure (IAP). Increased IAP may affect the circulatory and respiratory systems. When carbon dioxide is insufated in the abdom­inal cavity, the diaphragm is shifted to the cephalic side. This will potentially inuence the position of tracheal intubation, so anesthetists should assess the bilateral breath sounds fre­quently, especially in young children who have lower mainstem bronchi length. All these factors may lead to several inuences on the respiratory system, including decreased functional residual capacity, lower lung compliance, and high airway
resistance. Therefore, it will change the ventila­tion/ perfusion (V/Q) ratio and increase dead space ventilation, which can result in hypoxemia and hypercarbia. Position and CO2 absorption may inuence the circulatory system, including the increased systemic vascular resistance, higher pulmonary vascular resistance, and decreased cardiac index [7]. The pneumoperitoneum and reverse-Trendelenburg position may lead to an increase in stroke volume variation (SVV), MSFP and central venous pressure (CVP) and a decrease in the microcirculatory perfusion index [17]. In addition, with the increase in IAP levels, the inferior vena cava may be compressed, result­ing in a reduction in venous return ,which can lead to decreased cardiac output and hypoten­sion. In healthy pediatric patients, these changes can be compensated for a limited time and can easily offset by changes in ventilator parameters [18, 19]. However, in patients with pre- existing myocardial function injury, the impact may be magnied. Anesthetists should pay more atten­tion to patients with congenital heart disease (CHD ).
4.4 Robotic-Assisted Cardiac surgery
Currently, several cardiac operations also use robotic surgical systems, such as patent ductus arteriosus closure, atrial septal defect closure, ASD closure [20], and mitral valve replacement [5, 21
24]. Patients undergoing robotic cardiac surgery
need to be selected, especially in totally endoscopic robotic surgery. Factors limiting the RACS include the size of thorax and the distance between the mediastinum and anterolateral chest wall. Anesthetists should pay more attention to assessing whether the patient can tolerate the effects of pneu­mothorax on respiration and circulation and have a longer operation time compared to traditional surgery.
The plan for the induction of anesthesia is similar to the open procedure. Intraoperative monitoring included invasive blood pressure, pulse oximetry, EtCO2, central venous pres-
4 Pediatric Anesthesia forRobotic Surgery inChildren
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Fig. 4.3 PDA ligation assisted by robot
sure, and ECG. After the induction of anesthe­sia, some surgeries need one-lung ventilation; in some research, a left-sided double- lumen endo­tracheal tube (DLETT) is preferred for mitral valve replacement [25]. The inuences of OLV are the same as those of RATS.In robotic sur­geries, transesophageal echocardiography(TEE) was routinely checked, and the probe was placed through the surgeries. The process of placing a special cannula for extracorporeal circulation and cardioplegia is the same as in traditional cardiac surgery. Patients are always in lateral decubitus to meet the needs of surgery, and anesthetists should understand the effect of the patients’ posi­tion, OLV, and surgical manipulation. In the same time, every staff member should be trained to be able to quickly remove the robotic arms from the patient so that to convert to an open sternotomy (Fig. 4.3).
4.5 Robotic-Assisted Surgery inPediatric Gynecology
In the eld of pediatric gynecology, the use of robotic-assisted surgery is not as wide as in other departments . The use of robotic surgeries includes ovarian cystectomy, exploration for suspected malformation, and oophorectomy for gonadal dysgenesis [20, 26]. During surgery, the anesthetic considerations include the inuence of
25
patient positioning, such as Trendelenburg and lithotomy, pneumoperitoneum, and prevention of its associated complications [27].
4.6 Neonatal Robotic Surgery
The physiology of preterm and term neonates is quite different from that of adults, and the function of every system has not developed completely. Neonates have a fast respiratory rate of approxi­mately 40 cpm at rest. In neonates, the thorax is cylindrical, the intercostal muscles are weak, and breathing mainly depends on the action of the dia­phragm [28, 29]. However, the diaphragm of neo­nates is prone to fatigue. Additionally, the respiratory control system is immature in neo­nates, and the ventilation response when suffering hypercapnia and hypoxia is incomplete [30]. In awake neonates, functional residual capacity (FRC) is similar to that in adults, but alveolar ven­tilation is doubled. The heart rate of neonates uc­tuates over a wide range, ranging from 90 to 160bpm, and cardiac output is exquisitely heart­rate dependent. Therefore, the neonate does not improve cardiac output by increasing heart rate or adjusting total peripheral vascular resistance. Circulation in the neonate is similar to the situa­tion comparable to compensated shock in adults. The peripheral vascular resistance of neonates is high and cardiac output is mainly distributed in vital organs, such as the brain and heart. In addi­tion, in neonates, the function of the thermal regu­lating center is imperfect, the surface area is lager, the layer of insulating subcutaneous fat is thinner, and skin keratinization is lower. These factors may result in susceptibility to perioperative hypother­mia in neonates.
The considerations of neonatal robotic sur-
gery [31]:
1. The size of the surgical robot
2. Patients size: smaller cavities leading to decreased workplace size
3. The time of docking the robot
4. The inuence of pneumoperitoneum/pneu­mothorax
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The main inuence of robot-assisted abdomi­nal surgery is the pneumoperitoneum. During surgery, because of CO2 insufation, with the increase in IAP, respiratory function and pulmo­nary mechanics will be affected. Additionally, because of the pneumoperitoneum, the dia­phragm is pushed cephalad, which may reduce respiratory compliance and functional residual capacity [11]. Thus, it can cause atelectasis, which may potentially result from hypoxemia due to the neonate’s low closing volume. Head­down tilt positioning can also aggravate the loss of FRC [32]. As CO2 is absorbed, the risk of hypercarbia is higher in younger children than in older children. The pneumoperitoneum might further deteriorate V/Q mismatch. During sur­gery, it is necessary to limit the IAP to under 6mmHg in neonates [33] and apply an appropri­ate PEEP. For the sake of protecting neonates from intraoperative hypothermia, there are sev­eral simple measures such as raising the operat­ing room temperature to 28°C or 30°C, using a warming blanket, warming the solution for surgi­cal sterilization, and administering warm infu­sion solutions and blood [34].
References
1. Shen LT, Tou J. Application and prospects of robotic surgery in children: a scoping review. World J Pediatr Surg. 2022;5:e000482.
2. Ballouhey Q, Villemagne T, Cros J, etal. Assessment of paediatric thoracic robotic surgery. Interact Cardiovasc Thorac Surg. 2014;20:300–3.
3. Obasi PC, Hebra A, Varela JC.Excision of esophageal duplication cysts with robotic-assisted thoracoscopic surgery. JSLS. 2011;15:244–7.
4. Meehan JJ.Robotic surgery in small children: is there room for this? J Laparoendosc Adv Surg Tech A. 2009;19:707–12.
5. Suematsu Y, Mora BN, Mihaljevic T, et al. Totally endoscopic robotic-assisted repair of patent ductus arteriosus and vascular ring in children. Ann Thorac Surg. 2005;80:2309–13.
6. Anderberg M, Kockum CC, Arnbjornsson E. Morgagni hernia repair in a small child using da Vinci robotic instruments – a case report. Eur J Pediatr Surg. 2008;19:110–12.
7. Wakimoto M, Michalsky M, Nau O, et al. Anesthetic implications of robotic-assisted surgery in pediatric patients. Robot Surg. 2021;8:9–19.
8. Hammer GB. Single-lung ventilation in infants and children. Paediatr Anaesth. 2004;14:98–102.
9. Mukhtar AM, Obayah GM, Elmasry A, et al. The therapeutic potential of intraoperative hypercap­nea during video‐assisted thoracoscopy in pediatric patients. Anesth Analg. 2008;106:84–8.
10. Sauvat F, Michel JL, Benachi A, et al.Management of asymptomatic neonatal cystic adenomatoid malfor­mations. J Pediatr Surg. 2003;38:548–52.
11. Mukhtar AM, Obayah GM, Elmasry A, et al. The therapeutic potential of intraoperative hyper­capnia during video-assisted thoracoscopy in pediatric patients. Anesth Analg. 2008;106: 84–8.
12. Geraci Travis C, Prabhu S, Brent L, etal. Intraoperative anesthetic and surgical concerns for robotic thoracic surgery. Thorac Surg Clin. 2020;30:293–304.
13. Means LJ, Green MC, Bilal R. Anesthesia for minimally invasive surgery. Semin Pediatr Surg. 2004;13:181–7.
14. De Waal EE, Kalkman CJ.Haemodynamic changes during low-pressure carbon dioxide pneumo­peritoneum in young children. Paediatr Anaesth. 2003;13:18–25.
15. Hammer G, Hall S, Davis PJ. Anesthesia for gen­eral abdominal, thoracic, urologic, and bariatric surgery. Smith’s anesthesia for infants and children, vol. 2006. 7th ed. Pennsylvania: Elsevier Inc; 2006. p.686–8.
16. Xie X, Li Y, Li K, et al. Total robot-assisted chole­dochal cyst excision using da Vinci surgical system in pediatrics: Report of 10 cases. J Pediatr Surg. 2021;56:553–8.
17. He H, Gruartmoner G, Ince Y, et al. Effect of pneu­moperitoneum and steep reverse-Trendelenburg posi­tion on mean systemic lling pressure, venous return, and microcirculation during esophagectomy. J Thorac Dis. 2018;10:3399–408.
18. Neira VM, Kovesi T, Guerra L, etal. The impact of pneumoperitoneum and Trendelenburg positioning on respiratory system mechanics during laparoscopic pelvic surgery in children: a prospective observational study. Can J Anesth. 2015;62:798–806.
19. Kalfa N, Allal H, Raux O, etal. Tolerance of lapa­roscopy and thoracoscopy in neonates. Pediatrics. 2005;116:e785–91.
20. Pelizzo G, Nakib G, Calcaterra V. Pediatric and adolescent gynecology: Treatment perspec­tives in minimally invasive surgery. Pediatr Rep. 2019;11:8029.
21. Onan B, Aydin U, Kadirogullari E, et al. Totally endo­scopic robotic-assisted cardiac surgery in children. Artif Organs. 2019;43:342–49.
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22. Cannon Jeremy W, Howe Robert D, Dupont Pierre E, etal. Application of robotics in congenital cardiac surgery. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2003;6:72–83.
23. Ümit GA, Şahin Ş, Egemen E, et al. Feasibility of robotic-assisted atrial septal defect repair in a 6-year- old patient. Int J Med Robot. 2021; 17:e2185.
24. Le Bret E, Papadatos S, Folliguet T, et al. Interruption of patent ductus arteriosus in children: robotically assisted versus videothoracoscopic surgery. J Thorac Cardiovasc Surg. 2002;123: 973–6.
25. Rehfeldt KH, Andre JV, Ritter MJ. Anesthetic con­siderations in robotic mitral valve surgery. Ann Cardiothorac Surg. 2017;6:47–53.
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