Добавил:
Sekretar
kiopkiopkiop18@yandex.ru
t.me/Prokururor I Вовсе не секретарь, но почту проверяю
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз:
Предмет:
Файл:Ординатура / Хирургия / @xirurgi_2025 / @xirurgi_2025 - 220 - файл
.pdf
References
https://t.me/medicina_free
411
appendicitis occurring during pregnancy. BMJ.
1905;1(2305):463–5.
54. Goedecke No Title. Zentralbl f Gynäk 1912;15.
55. Maes U.A surgical consideration of appendicitis in
pregnancy. Am J Obstet Gynecol. 1934;27:214–24.
56. Abrahams R.Appendicitis complicating pregnancy.
Am J Obstet. 1897;35:205–25.
57. Barker D.Acute appendicitis and dietary bre: an
alternative hypothesis. BMJ. 1985;290:1125–7.
58. Burkitt D.Aetiology of the appendicitis. Br J Surg.
1971;58:695–9.
59. Mor G, Aldo P, Alvero AB. The unique immunological and microbial aspects of pregnancy. Nat Rev
Immunol. 2017;17:469–82.
60. Wegman H, Guilbert L, Mosmann TR.Bidirectional
cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?
Immunol Today. 1993;14:353–6.
61. Denney EL, Wadhwa PD, etal. Longitudinal modulation of immune system cytokine prole during
pregnancy. Cytokine. 2011;53:170–7.
62. Confavreux M, Hours MM, etal. Rate of pregnancyrelated relapses in multiple sclerosis. N Engl J Med.
1998;339:285–91.
63. Rom K, Aizenbud D, etal. Cigarette smoking and
inammation revisited. Respir Physiol Neurobiol.
2013;187:5–10.
64. Oldmeadow I, Mengersen K, et al. Investigation
of the relationship between smoking and appendicitis in Australian twins. Ann Epidemiol.
2008;18:631–6.
65. Schneider C, Schuetz J, et al. Smoking cessation
during pregnancy: a systematic literature review.
Drug Alcohol Rev. 2010;29:81–90.
66. Xu LM, Rissel C, etal. Smoking status and factors
associated with smoking of rst-time mothers during pregnancy and postpartum: ndings from the
healthy beginnings trial. Matern Child Health J.
2012;17:1151–7.
67. Bakhru TP. Smoking cessation and cardiovascular
disease risk factors: results from the Third National
Health and Nutrition Examination Survey. PLoS
Med. 2005;2:e160.
68. Hoffman M.Acute appendicitis in pregnancy; a tenyear survey. Am J Obstet Gynecol. 1954;67:1338–50.
69. Black W. Acute appendicitis in pregnancy. BMJ.
1960;1:1938–41.
70. Ciado. No Title. Rend de la Soc de biolog Paris
1892;4(27).
71. König, Muret M. No Title. Zeitschrift für
Geburtshilfe und gynecologie. 96:1359.
72. Tufer T.No Title. J d’Obstet et de Pediatr 1897;(7).
73. Jorgensen M.Recurrent appendicitis in each trimester of pregnancy, with a case report in each trimester.
Am J Surg. 1952;84:331–4.
74. Young BD, Levine D, Roque H.Medical management of ruptured appendicitis in pregnancy. Obstet
Gynecol. 2009;114:453–6.
75. Moriyama Y, Kotani T, Tsuda H, Ezaka K, Tanaka
C, Kikkawa F. Recurrent acute appendicitis dur-
ing the rst stage of labor. J Clin Gynecol Obstet.
2016;5:68–70.
76. Arnbjörnson E. Acute appendicitis risk in various
phases of the menstrual cycle. Acta Chir Scand.
1983;149:603–5.
77. Elder D, Abrahamson J, Schein M. The menstrual cycle and acute appendicitis. Eur J Surg.
1995;161:897–900.
78. Onder M, Arikanoglu Z, etal. Acute appendicitis
in pregnancy: evaluation of 129 patients during 20
years. J Curr Surg. 2012;2:4–10.
79. Easterling WN. The puerperium. In: Danforth JR,
editor. Obstetrics and Gynecology. Philadelphia: JP
Lippincott; 1986. p.755–66.
80. Sharma RK, Sharma SK.Appendicitis in pregnancy:
a novel approach for diagnostic dilemma. Sri Lanka
J Obstet Gynaecol. 2012;34:6–10.
81. Townsend FC. Appendicitis in pregnancy. South
Med J. 1976;69:1161–3.
82. Lebeau B, Kof E, etal. Appendicite aiguë et grossesse: a propos de 21 case. J Gynecol Obstet Biol
Reprod (Paris). 2005;34:600–5.
83. King GV.Appendicitis and pregnancy. Calif Med.
1962;97:158–62.
84. Hoffmann K.Zur Frage der Appendicitis in graviditate. Arch f Gynäk. 1920;112:230–56.
85. Schumacher P. Zur Kombination der
Röntgenbestrahlung mit Intravenösen
Traubenzucker-Injektionen. Klin Wochenschr
(Berlin). 1929;8:585–7.
86. Baer RA, Arens RA. Appendicitis in pregnancy:
with changes in position and axis of the normal
appendix in pregnancy. JAMA. 1932;98:1359–64.
87. Meharg FA. Acute appendicitis during pregnancy.
Obstet Gynecol. 1953;1:460–5.
88. Pankow O. Die urashen für die schlechte prognose der appendizitis in der schwangerschaft und
ihre bedeutung für die therapie. Arch f Gynäk.
1928;133:5–17.
89. Twyman RD, Stalker LK. Appendicitis in pregnancy: a review of seventy-ve cases. Mayo Clin
Proc. 1940;15:484.
90. Fink K.Die Diagnose und Differentialdiagnose der
Appendizitis bei Frauen. Monatschr f Gerburtsch u
Gynäk. 1925;71:328–38.
91. Hodjati T. Location of the appendix in the gravid
patient: a re-evaluation of the established concept.
Int J Gynaecol Obstet. 2003;81:245–7.
92. Zhang YY, Qiao J, Ye RH.Diagnosis of appendicitis
during pregnancy and perinatal outcome in the late
pregnancy. Chin Med J (Engl). 2009;122:521–4.
93. Oto PN, Ernst RD, etal. Revisiting MRI for appendix location during pregnancy. Am J Roentgenol.
2006;186:883–7.
94. Pates TC, Zaretsky MV, et al. The appendix in
pregnancy: conrming historical observations
with a contemporary modality. Obstet Gynecol.
2009;114:805–8.
95. Marbury W.Appendicitis in pregnancy. Am J Surg.
1933;19:437–41.

412
https://t.me/medicina_free
15 Acute Appendicitis
96. Jerlov E.Appendicitis during pregnancy and puerperium. Acta Obstet Gynecol Scand. 1925;4(Suppl):6.
97. Jerlov E. No Title. Acta Obstet Gynecol Scand
1929;4(Suppl):1.
98. Richards S.Diagnosis of acute appendicitis in pregnancy. Can J Surg. 1989;32:358–60.
99. Auguste B, Oyelese Y. Appendicitis in pregnancy
masquerading as recurrent preterm labor. Int J
Gynaecol Obstet. 2002;76:181–2.
100. Herczeg L, Keserü T. Premature labor and coincident acute appendicitis not resolved by betamimetic
but surgical treatment. Acta Obstet Gynecol Scand.
1983;62:373–5.
101. Dasari DK. The consequences of missing
appendicitis during pregnancy. BMJ Case Rep.
2011;2011:bcr.05.2011.4185.
102. Munde. No Title. Med Rec NewYork. 1984:46.
103. Hirst B.No Title. Transact Obstet Soc Philadephia
1890.
104. Mixter. No Title. Boston Med Surg J 1891.
105. Cappell M. Colon cancer during pregnancy: the
gastroenterologist’s perspective. Gastroenterol Clin
North Am. 1998;27(1):225–56.
106. Smith MK. Acute surgical emergencies of
the abdomen in pregnancy. N Engl J Med.
1940;223:529–31.
107. Masters BA, Gaskill HV, Sirinek KR. Diagnosing
appendicitis during pregnancy. Am J Surg.
1984;148:768–71.
108. Chen SJ, Tan KH, etal. Acute appendicitis during
pregnancy. J Med Sci. 1999;19:256–62.
109. DeVore G. Acute abdominal pain in the pregnant
patient due to pancreatitis, acute appendicitis, cholecystitis, or peptic ulcer disease. Clin Perinatol.
1980;7:349–69.
110. El Ghali MA, Kaabia O, Ben MZ, Jgham M, Tej A,
Sghayer A, etal. Acute appendicitis complicating
pregnancy: A 33 case series, diagnosis and management, features, maternal and neonatal outcomes. Pan
Afr Med J. 2018;30:212.
111. Hinshaw J.The acute abdomen complication pregnancy. J Oklahoma Med Assoc. 1963;56:4–7.
112. Ali H.Ectopic pregnancy presenting with obturator
nerve pain. J Accid Emerg Med. 1998;15:192–3.
113. Alders N. A sign for differentiating uterine from
extrauterine complications of pregnancy and puerperium. BMJ. 1951;2:1194–5.
114. Aaron C.A sign indicative of chronic appendicitis.
JAMA. 1913;60:350–1.
115. Kurtz RS, Sproul JD. Acute appendicitis in pregnancy and labor, a report of 41 cases. Obstet
Gynecol. 1964;23:528–32.
116. Nunnelee R, Spaner SD. Appendectomy in pregnancy and postpartum: analysis of data from a
large private hospital. Clin Excell Nurse Pract.
1999;3:298–301.
117. Hoshino Y, Suzuki T. Appendicitis during pregnancy. Int J Gynaecol Obstet. 2000;69:271–3.
118. Pastore DM, Sauret J.Appendicitis in pregnancy. J
Am Board Fam Med. 2006;19:621–6.
119. Wenzl M.Perforation eines Meckelschen Divertikels
bei Schwangerschaft. Wien Klin Wochenschr.
1949;61:249–50.
120. Eisdorfer J, Zinkin NT, Rivadeneira DE.Meckel’s
diverticulitis: a rare cause of abdominal pain during
pregnancy. ANZ J Surg. 2018;88(7–8):800–2.
121. Wong JYJ, Conroy M, Farkas N.Systematic review
of Meckel’s diverticulum in pregnancy. ANZ J Surg.
2021;91(9):E561–9.
122. Rudloff U, Jobanputra S, Smith-Levitin M, Kessler
E. Meckel’s diverticulum complicating pregnancy.
Case report and review of the literature. Arch
Gynecol Obstet. 2005;271:89–93.
123. Rudloff S, Smith-Levitin M, etal. Meckel’s diverticulum complicating pregnancy. Case report and
review of the literature. Arch Gynecol Obstet.
2005;271:89–93.
124. Cullen KA.Current management of Meckel’s diverticulum. Adv Surg. 1996;29:207–14.
125. Yahchouchy AF, Etienne JCF, Fingerhut
AL. Meckel’s diverticulum. J Am Coll Surg.
2001;192:658–62.
126. Matsagas M, Kouburos B, Giannoukas
AD. Incidence, complications, and management of Meckel’s diverticulum. Arch Surg.
1995;130:143–6.
127. St-Vil ML, Panic S, et al. Meckel’s diverticulum in children: a 20-year review. J Pediatr Surg.
1991;26:1289–92.
128. Yamaguchi S, Awazu S. Meckel’s diverticulum.
Investigation of 600 patients in Japanese literature.
Am J Surg. 1978;136:247–9.
129. Ahmed S, Kankaria J, Jenaw RK.Meckel’s diverticular perforation presenting as acute abdomen in
the second trimester of pregnancy. BMJ Case Rep.
2016;2016:bcr2016216643.
130. Cheng YC, Lo HC, et al. Laparoscopic appendectomy versus open appendectomy in pregnancy: a
population-based analysis of maternal outcome.
Surg Endosc. 2015;29:1394–9.
131. Polak JO.No Title. In: Proceedings of the Interstate
Post Graduate Medical Assembly of North America.
Michigan: Interstate Post Graduate Medical
Association of North America; 1929. p.234.
132. Reichert RF. Fitz-Hugh-Curtis syndrome. JAMA.
1976;236:266–8.
133. Dunnihoo JW, Wise RB, Otterson WN.Postpartum
ovarian vein thrombophlebitis: a review. Obstet
Gynecol Surv. 1991;46:415–27.
134. Kominiarek JU.Postpartum ovarian vein thrombosis:
an update. Obstet Gynecol Surv. 2006;61:337–42.
135. Hakim NN, Qushmaq KA, Al-Shami SY.An unusual
presentation of postpartum ovarian vein thrombosis.
Saudi Med J. 2007;28:273–5.
136. Prieto-Nieto JP, Rodriguez-Montes JA, GarciSancho- Martin L.Acute appendicitis- like symptoms
as initial presentation of ovarian vein thrombosis.
Ann Vasc Surg. 2004;18:481–3.
137. Twickler AT, Evans RS, etal. Imaging of puerperal
septic thrombophlebitis: prospective comparison of

References
https://t.me/medicina_free
413
MR imaging, CT and sonography. Am J Roentgenol.
1997;169:1039–43.
138. Witlin BM. Postpartum ovarian vein thrombosis
after vaginal delivery: a report of 11 cases. Obstet
Gynecol. 1995;85:775–80.
139. Arkadopoulos N, Dellaportas D, Yiallourou A,
Koureas A, Voros D.Ovarian vein thrombosis mimicking acute abdomen: a case report and literature
review. World J Emerg Surg. 2011;6(1):45.
140. Schwartz RR.Septic ovarian vein thrombophlebitis:
a surgical disease should be treated without operation. Eur J Surg. 1996;162:287–8.
141. Thomas DC, Igor DG.Ovarian and caval thrombosis: case reports. Tex Heart Inst J. 2005;32:579–82.
142. Salomon S, Shaham D, etal. Risk factors associated
with postpartum ovarian vein thrombosis. Thromb
Haemost. 1999;82:1015–9.
143. Committee on Practice Bulletins–Gynecology,
American College of Obstetricians and
Gynecologists. ACOG Practice Bulletin No. 84:
Prevention of deep vein thrombosis and pulmonary embolism. Obstet Gynecol. 2007;110(2 Pt
1):429–40.
144. Gaba MC. Where should pregnant women with
suspected nonobstetric issues be evaluated? Am J
Obstet Gynecol. 2015;125:19S.
145. Silvestri CM, Brousseau EC, et al. Morbidity
of appendectomy and cholecystectomy in pregnant and non-pregnant women. Obstet Gynecol.
2011;118:1261–70.
146. Amos SJ, Norman PF, et al. Laparoscopic surgery
during pregnancy. Am J Surg. 1996;171:435–7.
147. Yazar FM, Bakacak M, Emre A, Urfalioglu A, Serin
S, Cengiz E, etal. Predictive role of neutrophil-tolymphocyte and platelet-to-lymphocyte ratios for
diagnosis of acute appendicitis during pregnancy.
Kaohsiung J Med Sci. 2015;31:591–6.
148. Yilmaz Y, Bac B, et al. Acute appendicitis in
pregnancy–risk factors associated with principal outcomes: a case control study. Int J Surg.
2007;5:192–7.
149. Akbaş A, Aydın Kasap Z, Hacım NA, Tokoçin M,
Altınel Y, Yiğitbaş H, etal. The value of inammatory markers in diagnosing acute appendicitis in
pregnant patients. Ulus Travma Acil Cerrahi Derg.
2020;26(5):769–76.
150. Sadot DA, Arora M, et al. Laparoscopy: a safe
approach to appendicitis during pregnancy. Surg
Endosc. 2010;24:383–9.
151. Sarason S.Acute appendicitis in pregnancy: difculties in diagnosis. Obstet Gynecol. 1963;22:382–6.
152. Priddle HC. Acute appendicitis in the obstetric
patient. Am J Obstet Gynecol. 1951;62:150–5.
153. Melnick WL, Dalton VK. Management of general
surgical problems in the pregnant patient. Am J Surg.
2004;187:170–80.
154. Çınar H, Aygün A, Derebey M, Tarım İA, Akalın
BS, etal. Signicance of hemogram on diagnosis of
acute appendicitis during pregnancy. Ulus Travma
Acil Cerrahi Derg. 2018;24:423–8.
155. Mojibian S, Rahimi-Saghand S, et al. Maternal
serum C-reactive protein concentration in gestational diabetes. Iran J Diab Obes. 2011;3:54–9.
156. Omkara Murthy R, Dhananjaya BS, et al.
Pattern of C–reactive protein in pre-eclampsia
and normal pregnancy. Int J Biol Med Res.
2012;3:2616–21.
157. Kashanian F, Mahali N. Evaluation of the diagnostic value of the rst-trimester maternal serum
high-sensitivity C-reactive protein level for prediction of pre-eclampsia. J Obstet Gynaecol Res.
2013;39:1549–54.
158. Shaikh Y, Shaikh GS, Shaikh RB. Elevated serum
C-reactive protein level in obese pregnant women.
JLUMHS. 2012;11:7–10.
159. Picklesimer HL, Moss K, etal. Racial differences in
C-reactive protein levels during normal pregnancy.
Am J Obstet Gynecol. 2008;199(523):e1–6.
160. Van den Broe EA. Pregnancy and the erythrocyte
sedimentation rate. BJOG. 2001;108:1164–7.
161. Alvarado A. A practical score for the early diagnosis of acute appendicitis. Ann Emerg Med.
1986;15:557–64.
162. Kapan MA, Turhan AN, etal. Management of acute
appendicitis in pregnancy. Ulus Travma Acil Cerrahi
Derg. 2013;19:20–4.
163. Tatli F, Yucel Y, Gozeneli O, Dirican A, Uzunkoy A,
Yalçın HC, etal. The Alvarado Score is accurate in
pregnancy: a retrospective case–control study. Eur J
Trauma Emerg Surg. 2017;45:411–6.
164. Tinoco-González J, Rubio-Manzanares-Dorado M,
Senent-Boza A, Durán-Muñoz-Cruzado V, TallónAguilar L, Pareja-Ciuró F, etal. Acute appendicitis
during pregnancy: differences in clinical presentation, management, and outcome. Emergencias.
2018;30:261–4.
165. Saddique P, Ghazi A. Appendicitis in pregnancy;
does modied Alvarado score have a predictive
value. Pak J Surg. 2009;25:25–8.
166. Rosen A, Blake MA, et al. ACR Appropriateness
Criteria right lower quadrant pain-suspected appendicitis. J Am Coll Radiol. 2011;8:749–55.
167. Wallace MS, Soybel DI, etal. Inuence of imaging
on the negative appendectomy rate in pregnancy. J
Gastrointest Surg. 2008;12:46–50.
168. Negrete LM, Spalluto LB.Don’t be short-sighted:
cervical incompetence in a pregnant patient with
acute appendicitis. Clin Imaging. 2018;51:35–7.
169. Barloon BP, Abu-Yousef MM, etal. Sonography of
acute appendicitis in pregnancy. Abdom Imaging.
1995;20:149–51.
170. Lim SH, Seo GS. Diagnosis of acute appendicitis in pregnant women: value of sonography. Am J
Roentgenol. 1992;159:539–42.
171. Abu-Yousef JJ, Maher JW, et al. High-resolution
sonography of acute appendicitis. Am J Radiol.
1987;149:53–8.
172. Jeffrey FC, Lewis FR. Acute appendicitis: highresolution real-time US ndings. Radiology.
1987;163:11–4.

414
https://t.me/medicina_free
15 Acute Appendicitis
173. Puylaert J. Acute appendicitis. US evaluation using graded compression. Radiology.
1986;158:355–60.
174. Puylaert PH, Lalisang RI, etal. A prospective study
of ultrasonography in the diagnosis of appendicitis.
N Engl J Med. 1987;317:666–9.
175. Freeland E, Safcsak K, Durham R. Diagnosis
of appendicitis in pregnancy. Am J Surg.
2009;198:753–8.
176. Wong SY, Ng SS, etal. Giant Meckel’s diverticulitis:
a rare condition complicating pregnancy. Am J Surg.
2010;200:184–5.
177. Caspi AP, Mavor E, etal. The contribution of transvaginal ultrasound in the diagnosis of acute appendicitis: an observational study. Ultrasound Obstet
Gynecol. 2003;21:273–6.
178. Bramante M, Nelson M, Raio C.Appendicitis diagnosed by emergency physician performed Point-ofCare transvaginal ultrasound: case series. West J
Emerg Med. 2013;14:415–8.
179. Masselli G, Derchi L, McHugo J, Rockall A, Vock
P, Weston M, etal. Acute abdominal and pelvic pain
in pregnancy: ESUR recommendations. Eur Radiol.
2013;23:3485–500.
180. Garcia EM, Camacho MA, Karolyi DR, Kim DH,
Cash BD, Chang KJ, etal. ACR Appropriateness
Criteria ® Right Lower Quadrant PainSuspected Appendicitis. J Am Coll Radiol.
2018;15:S373–87.
181. Vu L, Ambrose D, Vos P, Tiwari P, Rosengarten M,
Wiseman S.Evaluation of MRI for the diagnosis of
appendicitis during pregnancy when ultrasound is
inconclusive. J Surg Res. 2009;156(1):145–9.
182. Kave M, Parooie F, Salarzaei M. Pregnancy and
appendicitis: a systematic review and meta-analysis
on the clinical use of MRI in diagnosis of appendicitis in pregnant women. World J Emerg Surg.
2019;14:37.
183. Fonseca KM, Kaplan LJ, etal. The use of magnetic
resonance imaging in the diagnosis of suspected
appendicitis in pregnancy: shortened length of stay
without increase in hospital charges. JAMA Surg.
2014;149:687–93.
184. Pedrosa D, Eyvazzadeh A, etal. MR imaging evaluation of acute appendicitis in pregnancy. Radiology.
2006;238:891–9.
185. Lukenaite B, Luksaite-Lukste R, Mikalauskas S,
Samuilis A, Strupas K, Poškus T. Magnetic resonance imaging reduces the rate of unnecessary
operations in pregnant patients with suspected acute
appendicitis: a retrospective study. Ann Surg Treat
Res. 2021;100:40–6.
186. Pedrosa M, Pandharipande PV, et al. Pregnant
patients suspected of having acute appendicitis:
effect of MR imaging on negative laparotomy
rate and appendiceal perforation rate. Radiology.
2009;250:749–57.
187. Cobben I, Haans L, et al. MRI for clinically suspected appendicitis during pregnancy. Am J
Roentgenol. 2004;183:671–5.
188. Shetty NM, Carpenter WS, etal. Abdominal computed tomography during pregnancy for suspected
appendicitis: a 5-year experience at a maternity hospital. Semin Ultrasound CT MRI. 2010;31:8–13.
189. Ames Castro TD, Castro EE, etal. The use of helical computed tomography in pregnancy for the diagnosis of acute appendicitis. Am J Obstet Gynecol.
2001;184:954–7.
190. Lazarus WW, Mainier MB, etal. CT in the evaluation of nontraumatic abdominal pain in pregnant
women. Radiology. 2007;244:784–90.
191. Dupuis P, Mellier G. Is helical computed tomography 100 % sensitive to diagnose acute appendicitis during pregnancy? Am J Obstet Gynecol.
2002;186:336.
192. Poletti PA, Botsikas D, Becker M, Picarra M,
Rutschmann OT, Buchs NC, et al. Suspicion of
appendicitis in pregnant women: emergency evaluation by sonography and low-dose CT with oral contrast. Eur Radiol. 2019;29:345–52.
193. Huerta A, Peck MA, etal. Meckel’s diverticulitis: a
rare etiology of an acute abdomen during pregnancy.
Curr Surg. 2006;63:290–3.
194. Joo J II, Park HC, Kim MJ, Lee BH.Outcomes of
antibiotic therapy for uncomplicated appendicitis in
pregnancy. Am J Med. 2017;130(12):1467–9.
195. Cai YL, Yang SS, Peng DZ, Jia QB, Li FY, Ye H,
et al. Laparoscopic appendectomy is safe and feasible in pregnant women during second trimester.
Medicine. 2020;99:e21801.
196. Nakashima M, Takeuchi M, Kawakami K.Clinical
outcomes of acute appendicitis during pregnancy:
conservative management and appendectomy. World
J Surg. 2021;45(6):1717–24.
197. Liu J, Ahmad M, Wu J, Tong XJ, Zeng HZ, Chan
FSY, etal. Antibiotic is a safe and feasible option
for uncomplicated appendicitis in pregnancy—A
retrospective cohort study. Asian J Endosc Surg.
2021;14(2):207–12.
198. Yang J, Wen SW, Krewski D, Corsi DJ, Walker M,
Mattison D, etal. Association of treatments for acute
appendicitis with pregnancy outcomes in the United
States from 2000 to 2016: results from a multi-level
analysis. PLoS One. 2021;16(12):e0260991.
199. Augustin G, di Saverio S.MRI is mandatory for the
assignment into antibiotic treatment or appendectomy group of patients during pregnancy. Am J Med.
2020;133:e208.
200. Ajjarapu A, Moreira N. Successful non-surgical
management of acute, uncomplicated appendicitis
in pregnancy: A case report. Proc Obstet Gynecol.
2020;9:8.
201. Amitai MM, Katorza E, Guranda L, Apter S,
Portnoy O, Inbar Y, etal. Role of emergency magnetic resonance imaging in the workup of suspected
appendicitis in pregnant women. Isr Med Assoc J.
2016;18:600–4.
202. Chung J, Berryman RP.An atypical case of a common pregnancy issue: appendicitis-like hyperemesis
gravidarum. Case Rep Med. 2020;2020:6959605.

References
https://t.me/medicina_free
415
203. Tavakoli A, Wadensweiler P, Blumenthal E, Kuncir
E, Houshyar R, Brueseke T. Medical management
of appendicitis in early-term pregnancy. BMJ Case
Rep. 2020;13(8):e234252.
204. Fulton B, Leon SM. Drainage with antibiotics is
effective therapy for appendicitis in pregnancy.
JAAPA. 2010;23:29–31.
205. Austin CS, Jaronczyk M.Safe laparoscopic appendectomy in pregnant patient during active labor. J
Surg Case Rep. 2021;2021(5):rjab127.
206. Abbasi V, Abenhaim HA. Evaluation of obstetrical and fetal outcomes in pregnancies complicated by acute appendicitis. Arch Gynecol Obstet.
2014;290:661–7.
207. McGory DS, Tillou A, et al. Negative appendectomy in pregnant women is associated with
a substantial risk of fetal loss. J Am Coll Surg.
2007;205:534–40.
208. Diddle AW.Trauma and interruption of pregnancy.
Tex State J Med. 1948;44:520–4.
209. Hiersch Y, Ashwal E, et al. The impact of pregnancy on the accuracy and delay in diagnosis of
acute appendicitis. J Matern Fetal Neonatal Med.
2014;27:1357–60.
210. Baruch Y, Canetti M, Blecher Y, Yogev Y, Grisaru
D, Nadav, et al. The diagnostic accuracy of
ultrasound in the diagnosis of acute appendicitis in pregnancy. J Matern Fetal Neonatal Med.
2019;33(23):3929–34.
211. Popkin PP, Cohn SM, etal. The incision of choice
for pregnant women with appendicitis is through
McBurney’s point. Am J Surg. 2002;183:20–2.
212. Donoghue F.Appendicitis complicating pregnancy,
with report of case; removal of gangrenous appendix at three and one-half months, delivery at term.
Boston Med Surg J. 1902;147:272–4.
213. McCorriston C. Nonobstetrical abdominal surgery during pregnancy. Am J Obstet Gynecol.
1963;86:593–9.
214. Kirshtein ZH, Avinoach E, etal. Safety of laparoscopic appendectomy during pregnancy. World J
Surg. 2009;33:475–80.
215. Gurbuz ME. The acute abdomen in the pregnant
patient. Surg Endosc. 1997;11:98–102.
216. Schreiber J. Laparoscopic appendectomy in pregnancy. Surg Endosc. 1990;4:100–2.
217. Upadhyay S, Kazantsev G, et al. Laparoscopic
management of a nonobstetric emergency in
the third trimester of pregnancy. Surg Endosc.
2007;21:1344–8.
218. Buitrago G, Arevalo K, Moyano JS, Caycedo R,
Gaitan H.Appendectomy in third trimester of pregnancy and birth outcomes: a propensity score analysis of a 6-year cohort study using administrative
claims data. World J Surg. 2020;44:12–20.
219. Hale M, Pearl RH, etal. Appendectomy: a contemporary appraisal. Ann Surg. 1997;225:252–61.
220. Lachman A, Voss E, et al. Pregnancy and laparoscopic surgery. J Am Assoc Gynecol Laparosc.
1999;6:347–51.
221. Kocael PC, Simsek K, etal. Laparoscopic surgery in
pregnant patients with acute abdomen. Ann Ital Chir.
2015;86:137–42.
222. Walsh T, Walsh SR. Laparoscopic versus open
appendectomy in pregnancy: a systematic review.
Int J Surg. 2008;6:339–44.
223. Eom JH, Jeon SW, etal. Safety and clinical efcacy
of laparoscopic appendectomy for pregnant women
with acute appendicitis. Ann Acad Med Singapore.
2012;41:82–6.
224. Jackson S, Price R, et al. Diagnosis and laparoscopic treatment of surgical diseases during pregnancy: an evidence-based review. Surg Endosc.
2008;22:1917–27.
225. Bennett N. Laparoscopic cholecystectomy in the
second trimester of pregnancy: a case report. J
Reprod Med. 1993;38:833–4.
226. Lyass A, Eisenberg VH, etal. Is laparoscopic appendicectomy safe in pregnant women? Surg Endosc.
2001;15:377–9.
227. de Perrot A, Morales M, etal. Laparoscopic appendicectomy during pregnancy. Surg Laparosc Endosc
Percutan Tech. 2000;10:368–71.
228. Machado CS. Laparoscopic appendicectomy in all
trimesters of pregnancy. JSLS. 2009;13:384–90.
229. Reedy HL, Richards WE, etal. Laparoscopy during
pregnancy: a study of laparoendoscopic surgeons. J
Reprod Med. 1997;42:33–8.
230. Curet M.Special problems in laparoscopic surgery.
Previous abdominal surgery, obesity, and pregnancy.
Surg Clin North Am. 2000;80:1093–110.
231. Moreno-Sanz A, Picazo-Yeste CPP, SeoaneGonzalez JB. Laparoscopic appendectomy
during pregnancy: between personal experiences and scientific evidence. J Am Coll Surg.
2007;205:37–42.
232. Peled L, Khalpari O, et al. Appendectomy during
pregnancy—is pregnancy outcome depending by
operation technique? J Matern Fetal Neonatal Med.
2014;27:365–7.
233. Reedy B, Kuehl TJ.Laparoscopy during pregnancy:
a study of ve fetal outcome parameters with use of
the Swedish Health Registry. Am J Obstet Gynecol.
1997;177:673–9.
234. Chung GS, Shin EJ, etal. Clinical outcomes compared between laparoscopic and open appendectomy
in pregnant women. Can J Surg. 2013;56:341–6.
235. Cho IS, Bae SU, Jeong WK, Baek SK. Singleport laparoscopic appendectomy for acute appendicitis during pregnancy. J Minim Access Surg.
2021;17(1):37–42.
236. Barnes MD, Schoemann MB, et al. Laparoscopic
appendectomy after 30 weeks pregnancy: report of
two cases and description of technique. Am Surg.
2004;70:733–6.
237. Iwamura S, Hashida H, Yoh T, Kitano S, Mizumoto
M, Kitamura K, et al. Laparoscopic appendectomy during the third trimester: Case presentation and literature review. Asian J Endosc Surg.
2018;11:413–6.

416
https://t.me/medicina_free
15 Acute Appendicitis
238. Pigne C, Giorgi H, et al. Appendiceal endometriosis disclosed by pregnancy. Med Chir Dig.
1980;9:721–2.
239. Perez C, Margolin G, Orris J.Appendiceal endometriosis presenting as acute appendicitis during pregnancy. Int J Obstet Gynecol. 2007;98:164–7.
240. Rollins KJ, Price RR.Laparoscopy for appendicitis
and cholelithiasis during pregnancy: a new standard
of care. Surg Endosc. 2004;18:237–41.
241. Lemieux P, Levesque I, etal. Laparoscopic appendectomy in pregnant patients: a review of 45 cases.
Surg Endosc. 2009;23:1701–5.
242. Bryan WJ. Surgical emergencies in pregnancy
and in the puerperium. Am J Obstet Gynecol.
1955;70:1204–11.
243. Saunders PJ. Laparotomy during pregnancy: an
assessment of diagnostic accuracy and fetal wastage.
BMJ. 1973;3:165–7.
244. Shnider GM. Maternal and fetal hazards of surgery during pregnancy. Am J Obstet Gynecol.
1965;92:891–900.
245. Stone K. Acute abdominal emergencies associated with pregnancy. Clin Obstet Gynecol.
2002;45:553–61.
246. Di Saverio G, Soa S, etal. Re: appendectomy in
pregnancy: evaluation of the risks of a negative
appendectomy. Am J Surg. 2012;204:560–1.
247. van den Broek AB, de Ruiter P, Gouma WB. A
normal appendix found during diagnostic laparoscopy should not be removed. Br J Surg.
2001;88:251–4.
248. Hussain H, Singhal T, etal. What is positive appendicitis? A new answer to an old question. Clinical,
macroscopical and microscopical ndings in 200
consecutive appendectomies. Singapore Med J.
2009;50:1145–9.
249. Wang DJ, Puri P.Is a histologically normal appendix
following emergency appendicectomy always normal. Lancet. 1996;347:1076–9.
250. Phillips AE, Sargen K.Should the macroscopically
normal appendix be removed during laparoscopy for
acute right iliac fossa pain when no other explanatory pathology is found? Surg Laparosc Endosc
Percutan Tech. 2009;19:392–4.
251. Halvorsen B, Andreasen JJ.Acute appendicitis in
pregnancy: complications and subsequent management. Eur J Surg. 1992;158:603–6.
252. Cullen KA, Moir CR, et al. Surgical management of Meckel’s diverticulum. An epidemiologic, population- based study. Ann Surg.
1994;220:564–8.
253. Nguyen H, Le K, Le C, Nguyen H. Concurrent
ruptured ectopic pregnancy and appendicitis. J Am
Board Fam Pract. 2005;18:63–6.
254. Riggs JC, Schiavello HJ, Fixler R. Concurrent
appendicitis and ectopic pregnancy. A case report. J
Reprod Med. 2002;47(6):510–4.
255. Ankouz A, Majdoub KI, etal. Simultaneous acute
appendicitis and ectopic pregnancy. J Emerg Trauma
Shock. 2009;2:46–7.
256. Hazebroek O, van der Harst E. Concurrent tubal
ectopic pregnancy and acute appendicitis. J Minim
Invasive Gynecol. 2008;15:97–8.
257. Pelosi J, Iffy L. Ectopic pregnancy as an etiologic agent in appendicitis. Obstet Gynecol.
1979;53:4S–6S.
258. Akman E, Damewood MD, etal. Perforated appendicitis and ectopic pregnancy following in-vitro fertilization. Hum Reprod. 1995;10:3325–6.
259. Barnett J, Hewitt J. Simultaneous rupturing heterotopic pregnancy and acute appendicitis in an
in-vitro fertilization twin pregnancy. Hum Reprod.
1999;14:850–1.
260. Biggs RL, Magann EF, O’Boyle JD. Concurrent
interstitial ectopic pregnancy and appendicitis: a case report. J Reprod Med Obstet Gynecol.
2008;53:378–81.
261. Radwan G, Malinowski MMB, A.Spontaneous heterotopic pregnancy and acute appendicitis treated by
laparoscopy. Int J Gynaecol Obstet. 2007;96:129.
262. Pate JD, Kindermann D, Hudson K. A case of
Hickam’s dictum: concurrent appendicitis and ectopic pregnancy. J Emerg Med. 2013;45(5):679–82.
263. Daponte M, Ioannou M, etal. Live birth after laparotomy for concurrent heterotopic pregnancy and
appendicitis in a 6 weeks IVF pregnancy. Arch
Gynecol Obstet. 2007;275:397–9.
264. Alaoui FZF, Laabadi K, Chaara H, Bouguern H,
Melhouf A. Acute appendicitis and simultaneous
ectopic pregnancy: about a rare case. Pan Afr Med
J. 2013;14:35.
265. Nguyen H, Le K, Le C, Nguyen H.Ruptured ectopic
pregnancy and appendicitis. J Am Board Fam Pract.
2005;18:63–6.
266. David E, Pessaux P, et al. Acute appendicitis and
ectopic pregnancy? Which came rst? J Visc Surg.
2011;4:e323.
267. Bozoklu S, Bozoklu E, Ciftci A, Coskun T.Ruptured
ectopic pregnancy with undetectable β-hCG levels coexisting with acute appendicitis. Acta Obstet
Gynecol Scand. 1997;76:181–2.
268. Chia P, Jeyarajah A. Co-existing tubal ectopic
pregnancy and appendicitis- a case report. Med J
Malaysia. 1996;51:485–7.
269. Thompson R, Hawe M. A rare pathological trinity: an appendiceal ectopic pregnancy, acute
appendicitis and a carcinoid tumour. Ir J Med Sci.
2011;180:579–80.
270. Wang R, Reynolds TA, West HH, Ravikumar D,
Martinez C, McAlpine I, etal. Use of a β-hCG discriminatory zone with bedside pelvic ultrasonography. Ann Emerg Med. 2011;58:12–20.
271. Rabbani DW.Heterotopic pregnancy is not rare: a
case report and literature review. J Obstet Gynaecol.
2005;25:204–5.
272. Dimitry R. Nine cases of heterotopic pregnancy
in 4 years of in-vitro fertilization. Fertil Steril.
1990;53:107–10.
273. Roest HV, Zeilmaker GH, Verhoeff A. The incidence of major clinical complications in a Dutch

References
https://t.me/medicina_free
417
transport IVF programme. Hum Reprod Update.
1996;2:345–53.
274. Van Hoorde A, Zeilmaker GH.Perforated appendicitis following transvaginal oocyte retrieval for invitro fertilization and embryo transfer. Hum Reprod.
1992;7:850–1.
275. Fujimoto Y, Yano T, etal. Ovarian hyperstimulation
syndrome complicated by peritonitis due to perforated appendicitis. Hum Reprod. 2002;17:966–7.
276. Abramov U, Schenker JG.Febrile morbidity in severe
and critical ovarian hyperstimulation syndrome: a
multicentre study. Hum Reprod. 1998;13:3128–31.
277. Fabregues J, Manau D, et al. Haematocrit, leukocyte and platelet counts and the severity of the
ovarian hyperstimulation syndrome. Hum Reprod.
1998;13:2406–10.
278. Laroche G. Primary and secondary peritonitis: an update. Eur J Clin Microbiol Infect Dis.
1998;17:542–50.
279. Allen RD, Cheung A. Pregnancy outcomes after
assisted reproductive technology. J Obstet Gynaecol
Can. 2006;28:220–50.
280. Jackson KA, Wu YW, Croughan MS.Perinatal outcomes in singletons following invitro fertilization:
a meta-analysis. Obstet Gynecol. 2004;103:551–63.
281. Romundstad PR, Sunde A, etal. Effects of technology or maternal factors on perinatal outcome after
assisted fertilisation: a population-based cohort
study. Lancet. 2008;372:737–43.
282. Nelson DA.Predicting live birth, preterm delivery,
and low birth weight in infants born from invitro
fertilisation: a prospective study of 144,018 treatment cycles. PLoS Med. 2011;8:e1000386.
283. Al-Mulhim A.Appendectomy during pregnancy in
sickle cell disease patients. Saudi J Gastroenterol.
2008;14:114–7.
284. Al-Nazer HH, Al-Salem AH. Acute appendicitis
in patients with sickle cell disease. Saudi Med J.
2003;24:974–7.
285. Antal M, Koshy M, Berman B.Is the incidence of
appendicitis reduced in patients with sickle cell disease? Pediatrics. 1998;101:E7.
286. Brant H. Acute appendicitis in pregnancy. Obstet
Gynecol. 1967;29:130–8.
287. Farquharson R. Acute appendicitis in pregnancy.
Scott Med J. 1980;25:36–8.
288. Al-Mulhim K.Pregnancy in sickle cell disease in the
Al Hassa region of Saudi Arabia. Ann Saudi Med.
2000;20:471–3.
289. Howard SM, Pearson TC.Pregnancy in sickle cell
disease in the UK: result of a multicentre survey of
the effect of prophylactic blood transfusion on maternal and fetal outcome. BJOG. 1995;102:947–51.
290. Leborgne-Samuel E, Venditelli F, et al. Sickle
cell anemia and pregnancy: review of 68 cases
in Guadeloupe. Gynecol Obstet Boil Rep.
2000;29:86–93.
291. von Rokitansky C.Ueber Uterusdrusen-Neubildung
in Uterus- und Ovarial-Sarcomen. Ztschr kk
Gesselsh Aerzte Wien. 1860;16:577.
292. Hirscberg A. Deciduale zellbildungen am
Wurmfortsatz bei Tubenschwangerschaft. Arch f
Gynäk. 1905;74:620–32.
293. Sampson J. Perforating hemorrhagic (chocolate)
cysts of ovary: their importance and especially their
relation to pelvic adenomas of endometrial type
(adenomyoma, of the uterus, rectovaginal septum,
sigmoid, etc.). Arch Surg. 1921;3:245–323.
294. Bogatko F. Endometriosis of the appendix in conjunction with pregnancy. J Am Med Womens Assoc.
1949;4:230–2.
295. Markou GA, Goubin-Versini I, Carbunaru OM,
Karatzios C, Muray JM, Fysekidis M.Macroscopic
deciduosis in pregnancy is nally a common
entity. Eur J Obstet Gynecol Reprod Biol. 2016
Feb;1(197):54–8.
296. Blair SP, Turner LJ, MacLeod MM.Review of the
pathologic diagnoses of 2,216 appendectomy specimens. Am J Surg. 1993;165:618–20.
297. Honore G. Extrapelvic endometriosis. Clin Obstet
Gynecol. 1999;42:699–711.
298. Ortiz-Hidalgo D, del la Pena O.Endometriosis of the
vermiform appendix (EVA) is an uncommon lesion
with a frequency < 1 % of all cases of pelvic endometriosis. Recent case. World J Surg. 1999;23:427.
299. Gustofson N, Liu S, Stratton P.Endometriosis and the
appendix: a case series and comprehensive review of
the literature. Fertil Steril. 2006;86:298–303.
300. Giorgakis E, Karydakis V, Farghaly A. Perforated
endometrial appendicitis in pregnancy. Hippokratia.
2012;16(2):181–3.
301. Ghazanfar A, Nasir SM, Choudary ZA, Ahmad
W. Acute appendicitis complicating pregnancy;
experience with the management of 50 patients. J
Ayub Med Coll Abbottabad. 2002;14(3):19–21.
302. Lane R.Endometriosis of the vermiform appendix.
Am J Obstet Gynecol. 1960;79:372–7.
303. Tedeschi GP.Endometriosis of the intestines: a report
of seven cases. Dis Colon Rectum. 1971;14:360–5.
304. Finch E.Acute appendicitis complicating pregnancy
in the Oxford region. Br J Surg. 1974;61:129–32.
305. Cutait JL, Camara-Lopes LH, etal. Endometriosis
of the vermiform appendix inducing acute appendicitis in a pregnant woman. Rev Paul Med.
1980;96:77–8.
306. Gini PC, Chukudebelu WO, Onuigbo
WIB.Perforation of the appendix during pregnancy;
a rare complication of endometriosis: case report.
BJOG. 1981;88(4):456–8.
307. Nielsen J, Thomsen JL. Endometriosis of the vermiform appendix. Acta Pathol Microbiol Immunol
Scand A. 1983;91:253–6.
308. Nakatani Y, Hara M, Misugi K, Korehisa
H.Appendiceal endometriosis in pregnancy. Report
of a case with perforation and review of the literature. Acta Pathol Jpn. 1987;37(10):1685–90.
309. Silvestrini IE, Marcial MA. Endometriosis of the
appendix with decidual polyp formation: a rare
cause of acute appendicitis during pregnancy. P R
Health Sci J. 1995;14(3):223–5.

418
https://t.me/medicina_free
15 Acute Appendicitis
310. Stefanidis S, Pappa L, Kontostolis E.Endometriosis
of the appendix with symptoms of acute appendicitis
in pregnancy. Obstet Gynecol. 1999;93:850.
311. Dimitriadis PA, Makar RR, Kingston G, Farouk
R. Appendiceal endometriosis and carcinoid presented as acute appendicitis in pregnancy: a rare case
report and review of the literature. Case Rep Obstet
Gynecol. 2013;2013:360459.
312. Lofwander M, Haugen G, Hammarstrom C,
Rokke O, Mathisen O. A pregnant woman with
abdominal pain and fever. Tidsskr Nor Laegeforen.
2007;127(19):2528–9.
313. Faucheron JL, Pasquier D, Voirin D.Endometriosis
of the vermiform appendix as an exceptional cause
of acute perforated appendicitis during pregnancy.
Colorectal Dis. 2008;10(5):518–9.
314. Packeisen HJ. Akute Appendizitis bei schwangerschaftsassoziierter ektoper Dezidua Fallbericht
und Überlegungen zur pathogenese. Pathologe.
1999;20:355–8.
315. Dogan E, Okyay E, Saatli B, Olgan S, Sarioglu S,
Koyuncuoglu M. Tuba ovarian abscesses formation from decidualized ovarian endometrioma after
appendiceal endometriosis presenting as acute
appendicitis in pregnancy. Iran J Reprod Med.
2012;10(3):275–8.
316. Lebastchi AH, Prieto PA, Chen C, Lui
FY.Appendiceal endometriosis in a pregnant woman
presenting with acute perforated appendicitis. J Surg
Case Rep. 2013;2013(12):rjt104.
317. Collom KS, Mehta SS, etal. Endometriosis of the
appendix masquerading as appendicitis in a 34-week
pregnant woman: case report and review of the literature. Austin J Surg. 2014;1(8):1040.
318. Balta M, Orube I, etal. Deciduosis of the appendix
manifesting as acute abdomen in pregnancy. Acta
chir Latviensis. 2014;14(1):43–5.
319. Murphy A, Wullschleger ME. Endometrial
decidualization: a rare cause of acute appendicitis during pregnancy. J Surg Case Rep.
2016;2016(4):rjw053.
320. Garcia H, Fodor M, Giovannoni A, Gidekel
L. Deciduosis of the appendix as cause of acute
abdomen in pregnancy. Medicina (Buenos Aires).
2001;61(2):185–6.
321. Kondoh M, Kakui K, et al. Deciduosis can cause
remarkable leukocytosis and obscure abdominal
pain. J Obstet Gynaecol Res. 2012;38:1376–8.
322. Kaneko M, Nozawa H, Rokutan H, Murono
K, Ushiku T, Ishihara S. Ectopic decidua of
the appendix: a case report. Surg Case Rep.
2021;7(1):117.
323. O’Donnell J, Garstin WI. Surgical treatment of
malignant carcinoid tumours of the appendix. Int J
Clin Pract. 2007;61:431–7.
324. Guraya GA, Ghallab A, Al Saigh A. Carcinoid
tumors of the appendix. Our experience in a university hospital. Saudi Med J. 2005;26:434–7.
325. Goede ME, Winslet MC.Carcinoid tumour of the
appendix. Br J Surg. 2003;90:1317–22.
326. Gilboa E, Or K, Achiron R.Carcinoid tumor of the
appendix: ultrasound ndings in early pregnancy.
Ultrasound Obstet Gynecol. 2008;31:576–8.
327. Pitiakoudis M, Tsaroucha A, etal. Carcinoid tumor
of the appendix during pregnancy. A rare case and
a review of the literature. J BUON. 2008;13:271–5.
328. Louzi Y, Belaabidia B, et al. Appendicular mucocele caused by carcinoid tumor during pregnancy.
Gynecol Obstet Fertil. 2006;34:1051–4.
329. Poiana M, Trifanescu R, etal. Case study of appendiceal carcinoid during pregnancy. J Med Life.
2012;5:325–8.
330. Berriors DR, Gibbs CE, Moore SF. Appendiceal
carcinoid tumors in pregnancy. Obstet Gynecol.
1965;26:428–31.
331. Scott TW. Argentafnoma of the appendix
in pregnancy: report of a case. IMJ Ill Med J.
1968;133:181–3.
332. Boudreaux DS, Hassan MM.The NANETS (North
American Neuroendocrine Tumor Society) consensus guideline for the diagnosis and management of
neuroendocrine tumors: well-differentiated neuroendocrine tumors of the Jejunum, Ileum, Appendix,
and Caecum. Pancreas. 2010;39:753–66.
333. Seyfer P, Jansen M, Mahnken AH.MR-guided percutaneous abscess drainage in pregnancy. J Vasc
Interv Radiol. 2016;27:1767–8.
334. Diettrich G.Surgical considerations in the contemporary management of biliary tract disease in the
postpartum period. Am J Surg. 1998;176:251–3.
335. Vasireddy S, Shennan A, Bewley S.Surgical management of appendicitis remains best option during
pregnancy. BMJ. 2012;344:e3575.
336. Wareld C. Acute appendicitis complicating pregnancy. Postgrad Med. 1950;8:10–4.
337. Babler E. Perforative appendicitis complicating
pregnancy. JAMA. 1908;51:1310–3.
338. Basaran M.Diagnosis of acute appendicitis during
pregnancy—a systematic review. Obstet Gynecol
Surv. 2009;64:481–8.
339. Kuvacic S, Zupancic B, Lovric H. Appendicitis
in the early puerperium: case report. Gynaecol
Perinatol. 2003;12:130–2.
340. Irvine RS, Wang HE.Postpartum appendicitis manifesting as umbilical purulence. Am J Emerg Med.
2010;28(262):e1–3.
341. Gerstle R. Postpartum appendicitis presenting as
RUQ pain. Am Fam Physician. 2008;77:282.
342. Murray A. Incidence and intensity of postpartum
lower abdominal pain. BMJ. 1989;17:298.
343. Tan E. Postpartum abdominal pain—have you
excluded a perforated ulcer? J Obstet Gynaecol.
2004;24:582–4.
344. Mahmoodian S. Appendicitis complicating pregnancy. South Med J. 1992;85:19–24.
345. Abrahams R.Abrahams R.Med Rec. 1895.
346. Fowler G. Observations upon appendicitis. Ann
Surg. 1894;19:146–71.
347. Füth H.Ueber die hohe Mortalität der Appendizitis
in graviditate and ihre Ursachen. 1913;39.

References
https://t.me/medicina_free
419
348. Meiling R. Appendicitis complicating pregnancy,
labor and the puerperium. Surg Gynecol Obstet.
1947;85:512–22.
349. Parker R. Acute appendicitis in late pregnancy.
Lancet. 1954;266:1252–7.
350. Corneille TM, Bening T, et al. The use of laparoscopic surgery in pregnancy: evaluation of safety
and efcacy. Am J Surg. 2010;200:363–7.
351. Reynolds J, Fuente S, etal. A review of laparoscopy
for non-obstetric-related surgery during pregnancy.
Curr Surg. 2003;60:164–73.
352. Holthausen L, Troidl H.Pregnancy: a contraindication? World J Surg. 1999;23:856–62.
353. Fatum N. Laparoscopic surgery during pregnancy.
Obstet Gynecol Surv. 2001;56:50–9.
354. Rizzo A.Laparoscopic surgery in pregnancy: long
term follow-up. J Laparoendosc Adv Surg Tech A.
2003;13:11–5.
355. Squires R. Surgical considerations in pregnancy.
Audiol Dig Genet Surg. 1998;45:6.
356. del Arévalo Pereira KMP, Giancarlo Buitrago
Gutiérrez G, Moyano Guacaneme JS, Caycedo
Beltrán R. Factores pronóstico asociados a parto
prematuro en mujeres sometidas a apendicectomía
durante el embarazo en un país de medianos ingresos.
Revista Colombiana de Cirugía. 2020;35:22–31.
357. Ananth S, Joseph KS, Kramer MS, etal. A comparison of foetal and infant mortality in the United States
and Canada. Int J Epidemiol. 2009;38:480–9.
358. Joseph L, Liu S, et al. Reconciling the high rates
of preterm and postterm birth in the United States.
Obstet Gynecol. 2007;109:813–22.
359. Ito H, Whang EE, Tavakkolizadeh A.Appendectomy
in pregnancy: evaluation of the risks of a negative
appendectomy. Am J Surg. 2012;203:145–50.
360. Beck D, Say L, et al. The worldwide incidence
of preterm birth: a systematic review of maternal
mortality and morbidity. Bull World Health Organ.
2010;88:31–8.
361. MacDorman FM, Mathews TJ.BirthStats: percentage of preterm births, United States and selected
European countries, 2004. Birth. 2010;37:168.
362. Mathews TJ, MacDorman MF.Infant mortality statistics from the 2005 period linked birth/infant death
data set. Natl Vital Stat Rep. 2008;57:1–32.
363. Hunt RW, Martin JN Jr, Martin RW, Meeks GR,
Wiser WL, Morrison JC.Perinatal aspects of abdominal surgery for nonobstetric disease. Am J Perinatol.
1989;6:412–7.
364. MacDorman FM, Kirmeyer S. Fetal and prenatal
mortality, United States, 2005. Natl Vital Stat Rep.
2009;57:1.
365. Augustin G, Boric M, Barcot O, Puljak L.Discordant
outcomes of laparoscopic versus open appendectomy for suspected appendicitis during pregnancy in
published meta-analyses: an overview of systematic
reviews. Surg Endosc. 2020;34:4245–56.
366. Chen YH, Li PC, Yang YC, Wang JH, Lin SZ,
Ding DC. Association of laparoscopy and laparotomy with adverse fetal outcomes: a retrospective
population- based case–control study. Surg Endosc.
2020;35(11):6048–54.
367. Tumati A, Yang J, Zhang X, Su J, Ward CA,
Hong J, et al. Pregnant patients requiring appendectomy: comparison between open and laparoscopic approaches in NY State. Surg Endosc.
2020;35(8):4681–90.
368. Afeck D, Egger M, Price R.The laparoscopic management of appendicitis and cholelithiasis during
pregnancy. Am J Surg. 1999;178:523–9.
369. Sekar H, Rajesh Thamaran N, Stoker D, Das S,
Yoong W.Should the laparoscopic approach be the
norm for appendicectomy in the third trimester of
pregnancy? BMJ Case Rep. 2019;12:e228192.
370. Hannan J, Hoque M, Begum LN. Laparoscopic
appendectomy in pregnant women: experience in Chittagong, Bangladesh. World J Surg.
2012;36:767–70.
371. Choi R, Lynn ET, Divino CM.Appendectomy during pregnancy: follow-up of progeny. J Am Coll
Surg. 2011;213:627–32.
372. Curet MJ, Vogt DA, Schob O, Qualls C, Izquierdo
LA, Zucker KA.Effects of CO2 pneumoperitoneum
in pregnant ewes. J Surg Res. 1996;63:339–44.

Biliary Tract Emergencies
https://t.me/medicina_free
16
Abstract
The most common causes of gallbladder disease in pregnancy are gallstones and biliary
sludge. In pregnancy, the incidence of gallbladder disease is 0.05–0.3%, and asymptomatic gallstones occur in 3.5–10% of all
pregnancies. Acute cholecystitis during pregnancy is one of the most common nonobstetric
operative conditions, and 40% of pregnant
patients with symptomatic cholelithiasis
require cholecystectomy during pregnancy.
Natural history and clinical examination are
similar to those in the nonpregnant population.
Therapeutic options are medical, open surgical, and laparoscopic procedures. Laparoscopy
is increasingly used. In the advanced third trimester, conservative treatment is recommended until delivery. 1/1200 pregnancies are
complicated by common bile duct stones.
Common bile duct stones have been observed
in 10–12.5% of pregnant women undergoing
cholecystectomy and account for 7% of cases
of jaundice in pregnancy. Diagnostic workup
and therapeutic management are complex and
depend on the maternal status, severity of the
disease, infection, duration of pregnancy, and
status of the fetus. Choledochal cysts are
extremely rare but rupture more frequently
than in nonpregnant populations.
16.1 Acute Cholecystitis/Biliary
Colic
16.1.1 Historical Perspective
Friedrich Daniel von Recklinghausen (1833–
1910) found that 90% of women with gallstones
have been gravid at least once. Subsequent ndings by Ludwig Georg Courvoisier (1843–1918)
in autopsy studies revealed that three times as
many women have gallstones as men, pointing at
pregnancy as one of the major risk factors for
cholelithiasis [1].
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
G. Augustin, Acute Abdomen During Pregnancy, https://doi.org/10.1007/978-3-031-26021-6_16
421
Соседние файлы в папке @xirurgi_2025
