- •Contents:
- •Introduction
- •Structure, functions and methods of research of biological membranes The general structure of cell
- •Ultrastrucrure and function of function of biological membrane
- •Kinds of passive transport
- •Methods of research of structure and functions of biological membranes
- •Method of a dark field.
- •Phase - contrast method.
- •Ultramicroscopy.
- •Electronic microscopy.
- •Method of diffraction of X-rays radiation.
- •Luminescent methods of research of membranes.
- •Method of ultrachemistry.
- •Nuclear magnetic resonance research and electronic paramagnetic resonance research.
- •Research of forces of a superficial tension Properties of liquids
- •Superficial tension.
- •Physical properties of biological membranes.
- •Molecular mechanisms of electrochemical potentials of membranes and distribution of a nervous impulse along excitability fibre.
- •Principles of transformation of biological and not electric signals in electric. Designs of sensors and electrodes, their basic characteristics
- •Application of sensors
- •Analog registering devices
- •Rhythm of heart. Parameters of cardiac activity.
- •External displays of activity of heart.
- •Activity of heart
- •Electric activity of cells of a myocardium
- •Functions of conductive system of heart
- •The electrocardiogram
- •Change of a rhythm of cardiac activity.
- •The device and main principles of work of electrocardiograph
- •Imposing of electrodes
- •The device, a principle of work of electroencephalograph. Basic rhythms of eeg. Registration of eeg and principles of the analysis
- •Introduction
- •Essence of a method
- •Technique of record of electroencephalogram.
- •Principles of analyses of electroencephalogram
- •Definition of a photoeffect
- •Types of photoeffects.
- •Einstein equation
- •Application of a photo effect in medicine.
- •The device, principle of work spectrophotometer. Application spectrophometrical methods of research for definition of concentration of substances in biological liquids
- •Method of the calibre graph.
- •Method of comparison.
- •Polarization of light by biosystems. Polarimeter. Light natural and polarized. Polaroids.
- •Research of microstructures in polarizing light
- •Rotation of a plane of fluctuations of polarized light. Saccharimetry.
- •Design of the device
- •Principle of action
- •Special receptions of microscopy of biological objects Special methods of light microscopy (illumination and supervision). Method of a dark field.
- •Method of ultramicroscopy
- •Method of a light field and its version
- •Method of phase contrast
- •Polarizing microscopy
- •The method interference contrast
- •Method of research in a view of a luminescence
- •Device of a microscope. Measurement of value of microscoping object.
- •Model of sliding strings. Biomechanics of a muscle. The equation of Hill. Modeling of muscular reduction Biophysics of muscular reduction
- •Structure of a cross-section-striped muscle. Model of sliding strands.
- •Biomechanics of a muscle
- •The equation of Hill. Power of single reduction.
- •Modelling of muscular reduction
- •Electromechanical interface in muscles
- •Devices for measurement of function of external breath. The device and a principle of work. Registration and the analysis of the given functional researches
- •Change of saturation by gases of an organism at differences of external pressure.
- •Biomechanics of external breath
- •Devices for measurement of function of external breath
- •Viscosity of a liquid
- •Current of a liquid on a horizontal pipe. Puazal’s law.
- •Current of a liquid on a pipe of variable section and branched out
- •Definition of speed of blood-groove
- •Full resistance (impedance) of tissues of the organism Physical bases of rheography
- •Measurement of factor of viscosity.
- •Physical bases of hemodynamic. Laws of movement of blood in an arterial and venous channel
- •Measurement of pressure of blood
- •Systolic and minute volume of a blood-groove
- •Change of minute volume of a blood-groove at work.
- •Biophysical features of an aorta.
- •Biophysical features of arterioles of the big circle of blood circulation.
- •Tomographic methods
- •Classification of kinds of a tomography.
- •Interposition of a source of probing radiation, bject and the detector.
- •Echosounding
- •Computer tomograph.
- •Magnetic-resonant tomography.
- •Three-dimensional ultrasonic
- •ElastoScan-flexography
- •Modes of an acoustic transparency of three-dimensional ultrasonic.
- •Methods of physiotherapeutic influence
- •The therapeutic techniques based on application of a direct current. Electrophoresis and galvanizing in a medical practice. Mobility of ions.
- •Medicinal electrophoresis.
- •Galvanizing.
- •Electrosecurity
- •The basic requirements to an electrosecurity of electromedical devices and devices.
- •Modelling of biophysical processes.
- •The basic stages of modelling
- •The basic stages of modelling
- •4. Creation of model, its research.
- •Classification of models:
- •Mathematical models of growth of number of a population.
- •Pharmacokinetic model.
- •Sources of X-ray radiation.
- •Artificial sources of radiation.
- •Interaction of X-ray radiation with substance.
- •1. Coherent dispersion;
- •2. Photoeffect
- •3. Kompton - effect
- •Radioactivity radiation Radioactive disintegration Structure of a nucleus
- •A radioactive disintegration. Kinds of radioactive radiation
- •It is thrown out and a nucleus has more stability complex of nucleons. Positron β-disintegration is described by the equation:
- •The basic law of radioactive disintegration in the differential form. A constant of disintegration.
- •The basic law of radioactive disintegration in the differential form.
- •A half-life period.
- •Activity. A unit of measure.
- •Radioactive elements in the nature.
- •Ionizing radioactive radiation and its biological action.
- •The absorbed and exposition doze. Power of a doze. Units of measure.
- •Relative biological efficiency.
- •Mehanisms of action of laser radiation on biological tissues.
- •Mechanisms of action of laser radiation on biological tissues
- •Список использованной литературы :
- •Educational handout on medical biophysics kovaleva larissa valentinovna
A half-life period.
Half-life period T 1/2 determine speed of disintegration of various elements in practice. Half of initial number of radioactive nucleuses breaks up during this time. The half-life period T 1/2 can be found from following reasons. If
then quantity of not broken nucleuses is equal to
,
Whence
,
hence,
The half-life period of elements (isotopes) differs in wide limits - from millions years up to shares of second.
Activity. A unit of measure.
The general quantity of the disintegrations happening in unit of time has the major importance in practical use of sources of radioactive radiation. This quantity is named activity A of given source of radioactive radiation. Activity depends upon speed of disintegration and initual quantity of nucleuses, i.e. mass of isotope.
Activity determine absolute speed of disintegration of isotope in given source.
If we compare of formulas of the basic law and a half-life period then it follows:
Activity of an element is proportional to quantity of nucleuses (mass of isotope) and inversely proportional to its half-life period.
We have some kinds of units for determinate activity of radioactivity element. Quire is unit of measure of activity of such element, which gives 3.7 1010 disintegrations in a second. We can use unit of activity - Reserford also, which correspond 106 disintegrations in a second.
Radioactive elements in the nature.
Radioactive
elements there are in the nature, but in small quantities.
Radioactive elements contain mainly in uranium ores in an earth's
crust. There is a radioactive isotope of potassium
in
the ground contain and isotopes of hydrocarbon
14C
and
hydrogen
3H,
which
are formed in an atmosphere and penetrate from atmosphere to the
ground. There are the radioactive substances, which are washed away
from ground and rocks in natural waters. These sources are used for
the medical purposes. Plants acquire radioactive substances from
ground, waters and atmospheres. The isotope of carbon
is
formed in an atmosphere, from nitrogen
under
action of neutrons of space radiation. This process we can write with
help chemical equition:
It is acquired by plants at photosynthesis. The radioactive substances penetrate to animal organisms with food, water and air, but also are removed with excrement. Therefore their accumulation in an organism does not occur happen.
There is a radioactive radiation everywhere in the nature, where there are radioactive substances, which makes natural radioactive backgraund together with spase radiation. Plants and animals have adapted to this radioactive background, as well as to other physical factors of an environment.
Ionizing radioactive radiation and its biological action.
Radioactive radiations and rigid x-rays and as streams of protons and neutrons are united under the general name of an ionizing radiation. Speed and energy of the protons, which are thrown out at nuclear reactions, getting and ionizing ability of these particles same, as well as alpha - particles. Elastic dispersion can happen at impact of neutrons to nucleus, not elastic dispersion and capture of a neutron by a nucleus (radiating capture) can be also.
Action of ionizing radiation can cause infringement in structure of molecules of substances. For example: it is possible to specify distillict waters, which consists from ionization and the subsequent disintegration of the ionized molecule of water with formation of nonsaturated radicals Н and OH, not having electric charges, but having nonsaturated valencies and having exclusively high chemical activity, thus forms also connections of type Н2О2 or НО2, they are very strong oxidizers.
