- •Contents:
- •Introduction
- •Structure, functions and methods of research of biological membranes The general structure of cell
- •Ultrastrucrure and function of function of biological membrane
- •Kinds of passive transport
- •Methods of research of structure and functions of biological membranes
- •Method of a dark field.
- •Phase - contrast method.
- •Ultramicroscopy.
- •Electronic microscopy.
- •Method of diffraction of X-rays radiation.
- •Luminescent methods of research of membranes.
- •Method of ultrachemistry.
- •Nuclear magnetic resonance research and electronic paramagnetic resonance research.
- •Research of forces of a superficial tension Properties of liquids
- •Superficial tension.
- •Physical properties of biological membranes.
- •Molecular mechanisms of electrochemical potentials of membranes and distribution of a nervous impulse along excitability fibre.
- •Principles of transformation of biological and not electric signals in electric. Designs of sensors and electrodes, their basic characteristics
- •Application of sensors
- •Analog registering devices
- •Rhythm of heart. Parameters of cardiac activity.
- •External displays of activity of heart.
- •Activity of heart
- •Electric activity of cells of a myocardium
- •Functions of conductive system of heart
- •The electrocardiogram
- •Change of a rhythm of cardiac activity.
- •The device and main principles of work of electrocardiograph
- •Imposing of electrodes
- •The device, a principle of work of electroencephalograph. Basic rhythms of eeg. Registration of eeg and principles of the analysis
- •Introduction
- •Essence of a method
- •Technique of record of electroencephalogram.
- •Principles of analyses of electroencephalogram
- •Definition of a photoeffect
- •Types of photoeffects.
- •Einstein equation
- •Application of a photo effect in medicine.
- •The device, principle of work spectrophotometer. Application spectrophometrical methods of research for definition of concentration of substances in biological liquids
- •Method of the calibre graph.
- •Method of comparison.
- •Polarization of light by biosystems. Polarimeter. Light natural and polarized. Polaroids.
- •Research of microstructures in polarizing light
- •Rotation of a plane of fluctuations of polarized light. Saccharimetry.
- •Design of the device
- •Principle of action
- •Special receptions of microscopy of biological objects Special methods of light microscopy (illumination and supervision). Method of a dark field.
- •Method of ultramicroscopy
- •Method of a light field and its version
- •Method of phase contrast
- •Polarizing microscopy
- •The method interference contrast
- •Method of research in a view of a luminescence
- •Device of a microscope. Measurement of value of microscoping object.
- •Model of sliding strings. Biomechanics of a muscle. The equation of Hill. Modeling of muscular reduction Biophysics of muscular reduction
- •Structure of a cross-section-striped muscle. Model of sliding strands.
- •Biomechanics of a muscle
- •The equation of Hill. Power of single reduction.
- •Modelling of muscular reduction
- •Electromechanical interface in muscles
- •Devices for measurement of function of external breath. The device and a principle of work. Registration and the analysis of the given functional researches
- •Change of saturation by gases of an organism at differences of external pressure.
- •Biomechanics of external breath
- •Devices for measurement of function of external breath
- •Viscosity of a liquid
- •Current of a liquid on a horizontal pipe. Puazal’s law.
- •Current of a liquid on a pipe of variable section and branched out
- •Definition of speed of blood-groove
- •Full resistance (impedance) of tissues of the organism Physical bases of rheography
- •Measurement of factor of viscosity.
- •Physical bases of hemodynamic. Laws of movement of blood in an arterial and venous channel
- •Measurement of pressure of blood
- •Systolic and minute volume of a blood-groove
- •Change of minute volume of a blood-groove at work.
- •Biophysical features of an aorta.
- •Biophysical features of arterioles of the big circle of blood circulation.
- •Tomographic methods
- •Classification of kinds of a tomography.
- •Interposition of a source of probing radiation, bject and the detector.
- •Echosounding
- •Computer tomograph.
- •Magnetic-resonant tomography.
- •Three-dimensional ultrasonic
- •ElastoScan-flexography
- •Modes of an acoustic transparency of three-dimensional ultrasonic.
- •Methods of physiotherapeutic influence
- •The therapeutic techniques based on application of a direct current. Electrophoresis and galvanizing in a medical practice. Mobility of ions.
- •Medicinal electrophoresis.
- •Galvanizing.
- •Electrosecurity
- •The basic requirements to an electrosecurity of electromedical devices and devices.
- •Modelling of biophysical processes.
- •The basic stages of modelling
- •The basic stages of modelling
- •4. Creation of model, its research.
- •Classification of models:
- •Mathematical models of growth of number of a population.
- •Pharmacokinetic model.
- •Sources of X-ray radiation.
- •Artificial sources of radiation.
- •Interaction of X-ray radiation with substance.
- •1. Coherent dispersion;
- •2. Photoeffect
- •3. Kompton - effect
- •Radioactivity radiation Radioactive disintegration Structure of a nucleus
- •A radioactive disintegration. Kinds of radioactive radiation
- •It is thrown out and a nucleus has more stability complex of nucleons. Positron β-disintegration is described by the equation:
- •The basic law of radioactive disintegration in the differential form. A constant of disintegration.
- •The basic law of radioactive disintegration in the differential form.
- •A half-life period.
- •Activity. A unit of measure.
- •Radioactive elements in the nature.
- •Ionizing radioactive radiation and its biological action.
- •The absorbed and exposition doze. Power of a doze. Units of measure.
- •Relative biological efficiency.
- •Mehanisms of action of laser radiation on biological tissues.
- •Mechanisms of action of laser radiation on biological tissues
- •Список использованной литературы :
- •Educational handout on medical biophysics kovaleva larissa valentinovna
Technique of record of electroencephalogram.
F
or
reception of a high-grade picture of bioelectric activity of a brain
careful installation of skin or needle electrodes is need. Thus
observance of strict symmetry relatively of anterior a line is
necessary, to try to install electrodes on identical distance from
each other that they were above all basic departments of surfaces of
a brain: frontal, central, parietal, cervical, temporal.
Fig. 6.
I
n
applied medicine the international system of installation of
electrodes is used "10-20 %" (Fig. 6). According to this
system at each examinee precisely measure distance
between
the middle of nose bridge and external occipital protuberance
(inion), and also between the left and right ear poles. Possible
points of an arrangement of electrodes are divided by the intervals
making 10 % or 20 % of these distances on a skull. Thus for
convenience of registration all skull is broken into the areas
designated by letters: F-frontal, About-occipital area, Р-parietal,
Т-temporal,
С-area
central line.
Registration of EEG is made by special electrodes. Each electrode is connected to the amplifier.
Record of potentials from each electrode is carried out concerning zero potential of the reviewer to which is accepted lobe of the ear, or a tip of a nose.
Computer electroencephalograph «Компакт-нейро» - 16 channel device.
In electroencephalography two variants of taps subdivided on monopolar (referent) and bipolar are use.
Such tap is called monopolar when on one of entrance clamp of the amplifier the electric potential from an electrode which is above a brain moves, and on another clamp- potential from the electrode established on certain removal from a brain, or some average potential caused by any local source. The electrode located above a brain, is called active. The electrode removed from a brain tissue is called passive, referent, indifferent.
Referent electrode is located on lobe of the ear, on a chin or sometimes on a nose. An establishment of referent electrode on more removed parts of a body have a number of the difficulties partly connected with fixing of an electrode, but mainly, with handicapes from others электрически active bodies of a body - muscles and heart.
Tap is called bipolar at which to positive and negative to entrance clamp of the amplifier connect the electrodes which are above a brain.
For reception of qualitative EEG it is desirable to place the patient in an armchair, in the weakened pose, blindly. At first recording of EEG is made, then various tests are made: in the form of sound and light irritations, test with opening and closing of eyes with supervision over dynamics of the basic rhythms.
Now the test with hyperventilation is most widespread: the patient deeply and rhythmically breathes within 1 minutes; thus registration EEG is carried out not less than 3 minutes during and after carrying out of hyperventilation.
It is possible to apply pharmacological tests, entering during record EEG those or other preparations depending on the purpose of inspection.
