- •Contents:
- •Introduction
- •Structure, functions and methods of research of biological membranes The general structure of cell
- •Ultrastrucrure and function of function of biological membrane
- •Kinds of passive transport
- •Methods of research of structure and functions of biological membranes
- •Method of a dark field.
- •Phase - contrast method.
- •Ultramicroscopy.
- •Electronic microscopy.
- •Method of diffraction of X-rays radiation.
- •Luminescent methods of research of membranes.
- •Method of ultrachemistry.
- •Nuclear magnetic resonance research and electronic paramagnetic resonance research.
- •Research of forces of a superficial tension Properties of liquids
- •Superficial tension.
- •Physical properties of biological membranes.
- •Molecular mechanisms of electrochemical potentials of membranes and distribution of a nervous impulse along excitability fibre.
- •Principles of transformation of biological and not electric signals in electric. Designs of sensors and electrodes, their basic characteristics
- •Application of sensors
- •Analog registering devices
- •Rhythm of heart. Parameters of cardiac activity.
- •External displays of activity of heart.
- •Activity of heart
- •Electric activity of cells of a myocardium
- •Functions of conductive system of heart
- •The electrocardiogram
- •Change of a rhythm of cardiac activity.
- •The device and main principles of work of electrocardiograph
- •Imposing of electrodes
- •The device, a principle of work of electroencephalograph. Basic rhythms of eeg. Registration of eeg and principles of the analysis
- •Introduction
- •Essence of a method
- •Technique of record of electroencephalogram.
- •Principles of analyses of electroencephalogram
- •Definition of a photoeffect
- •Types of photoeffects.
- •Einstein equation
- •Application of a photo effect in medicine.
- •The device, principle of work spectrophotometer. Application spectrophometrical methods of research for definition of concentration of substances in biological liquids
- •Method of the calibre graph.
- •Method of comparison.
- •Polarization of light by biosystems. Polarimeter. Light natural and polarized. Polaroids.
- •Research of microstructures in polarizing light
- •Rotation of a plane of fluctuations of polarized light. Saccharimetry.
- •Design of the device
- •Principle of action
- •Special receptions of microscopy of biological objects Special methods of light microscopy (illumination and supervision). Method of a dark field.
- •Method of ultramicroscopy
- •Method of a light field and its version
- •Method of phase contrast
- •Polarizing microscopy
- •The method interference contrast
- •Method of research in a view of a luminescence
- •Device of a microscope. Measurement of value of microscoping object.
- •Model of sliding strings. Biomechanics of a muscle. The equation of Hill. Modeling of muscular reduction Biophysics of muscular reduction
- •Structure of a cross-section-striped muscle. Model of sliding strands.
- •Biomechanics of a muscle
- •The equation of Hill. Power of single reduction.
- •Modelling of muscular reduction
- •Electromechanical interface in muscles
- •Devices for measurement of function of external breath. The device and a principle of work. Registration and the analysis of the given functional researches
- •Change of saturation by gases of an organism at differences of external pressure.
- •Biomechanics of external breath
- •Devices for measurement of function of external breath
- •Viscosity of a liquid
- •Current of a liquid on a horizontal pipe. Puazal’s law.
- •Current of a liquid on a pipe of variable section and branched out
- •Definition of speed of blood-groove
- •Full resistance (impedance) of tissues of the organism Physical bases of rheography
- •Measurement of factor of viscosity.
- •Physical bases of hemodynamic. Laws of movement of blood in an arterial and venous channel
- •Measurement of pressure of blood
- •Systolic and minute volume of a blood-groove
- •Change of minute volume of a blood-groove at work.
- •Biophysical features of an aorta.
- •Biophysical features of arterioles of the big circle of blood circulation.
- •Tomographic methods
- •Classification of kinds of a tomography.
- •Interposition of a source of probing radiation, bject and the detector.
- •Echosounding
- •Computer tomograph.
- •Magnetic-resonant tomography.
- •Three-dimensional ultrasonic
- •ElastoScan-flexography
- •Modes of an acoustic transparency of three-dimensional ultrasonic.
- •Methods of physiotherapeutic influence
- •The therapeutic techniques based on application of a direct current. Electrophoresis and galvanizing in a medical practice. Mobility of ions.
- •Medicinal electrophoresis.
- •Galvanizing.
- •Electrosecurity
- •The basic requirements to an electrosecurity of electromedical devices and devices.
- •Modelling of biophysical processes.
- •The basic stages of modelling
- •The basic stages of modelling
- •4. Creation of model, its research.
- •Classification of models:
- •Mathematical models of growth of number of a population.
- •Pharmacokinetic model.
- •Sources of X-ray radiation.
- •Artificial sources of radiation.
- •Interaction of X-ray radiation with substance.
- •1. Coherent dispersion;
- •2. Photoeffect
- •3. Kompton - effect
- •Radioactivity radiation Radioactive disintegration Structure of a nucleus
- •A radioactive disintegration. Kinds of radioactive radiation
- •It is thrown out and a nucleus has more stability complex of nucleons. Positron β-disintegration is described by the equation:
- •The basic law of radioactive disintegration in the differential form. A constant of disintegration.
- •The basic law of radioactive disintegration in the differential form.
- •A half-life period.
- •Activity. A unit of measure.
- •Radioactive elements in the nature.
- •Ionizing radioactive radiation and its biological action.
- •The absorbed and exposition doze. Power of a doze. Units of measure.
- •Relative biological efficiency.
- •Mehanisms of action of laser radiation on biological tissues.
- •Mechanisms of action of laser radiation on biological tissues
- •Список использованной литературы :
- •Educational handout on medical biophysics kovaleva larissa valentinovna
Viscosity of a liquid
Rheology is a science about deformations and fluidity of substance. studying of biophysical features of blood as viscous liquid is rheology of blood (gemorheology). In a real liquid between molecules the forces of a mutual attraction, causing internal friction operate. Internal friction, for example, causes force of resistance at mixing of a liquid.
In a
real liquid of a molecule are drawn to each other and create internal
friction. It is shown as force of resistance at hashing a liquid. At
laminar current the liquid shares on layers, moving in parallel with
various speeds. Newton has established, that force of internal
resistance between two layers depends by nature liquids and is
directly proportional to the area of adjoining layers and change of
speed at transition from a layer to a layer dv/dz
F= ηS dv/dz,
where η - factor of viscosity of a liquid or simply viscosity. Unit of measure of factor of viscosity in SI is Pascal-second. The liquid in which on a layer the area 1m operates force of internal friction 1 Newton at a gradient of speed 1m/sec has such viscosity.
However at measurements use other unit - poise is more often. 1 poise - there is a viscosity of a liquid, if on a layer 1 cm at a gradient of speed 1N/sec force 1 dyne operates. Other unit of viscosity is N∙s/m2.
The viscosity is depended on condition and molecular properties of liquids (or gase). For the characteristic of viscosity of a liquid in practice relative viscosity of a liquid is used ηr= η/η0 , η- viscosity of a liquid η0 - viscosity of water at identical temperature. At the majority of liquids (the water, the fused metals and their salts low-molecular connections) viscosity depends by nature liquids and temperatures. Such liquids refer to Nuton's liquid. At some liquids (solutions of polymers) or dispersive systems (suspensions) viscosity depends from also on a mode of current of a liquid - pressure and a gradient of speed. Such liquids refer to nonNuton's liquid.
Distinguish laminar and turbulent current of a liquid At laminar current a liquid it is divided into molecular layers which move with various speeds do not mix up Such character of current of a liquid has at slow movement of a liquid on a pipe the layer of the molecules adjoining to a wall of a pipe, sticks to it and does not move. The following layer of molecules is displaced under action of force of pressure and force of internal friction. Each following layer of molecules is displaced concerning previous and speed of each layer increases. Thus, speed of molecular layers of a liquid is maximal in the center of a pipe.
If speed of particles in a liquid randomly varies, particles pass from one layer in another such movement of a liquid refers to turbulent.
If the liquid flows on a horizontal pipe its potential energy is spent for work on overcoming internal friction, therefore static pressure gradually decreases.
The blood is suspension of formed elements in protein's solution-plasma. Therefore it must be nonNewton liquid. In addition at movement of blood in vessels the concentration of formed elements increases in central part of stream wherein consequence of the viscosity increased. But so far as the blood's viscosity is not so great these phenomenon are neglected and blood's coefficient of viscosity is considering being constant. The relative viscosity of blood is completed in norm 4,2-6. Under pathology it can decrease till 2-3 (under anaemia) or increase till 15-20 (under polycetemia). The viscosity of blood's serum is in standard 1,64-1,69 and under pathology -1,5-2,0.
Change of viscosity of blood is one of the reasons of change of speed of subsidence erythrocytes. Viscosity of blood has diagnostic value. Some infectious diseases increase viscosity, others, for example a belly typhus and a tuberculosis - reduce.
Relative viscosity serum of blood in norm 1,64-1,69 and at a pathology 1,5-2,0. As well as at any liquid, viscosity of blood increases at decrease of the temperature. At increase of rigidity of erythrocytic membranes, for example at an atherosclerosis, viscosity of blood also increases, that leads to increase in loading at heart. Viscosity of blood different in wide and narrow vessels, and influence of diameter of a blood vessel on viscosity starts to affect at a gleam less than 1 mm. In vessels 0,5 mm viscosity decreases in linear response to reduction of diameter, because erythrocytes are built along an axis of vessels in a chain like “snake” and are surrounded by a layer of the plasma isolating “snake” from a vascular wall.
