- •Contents:
- •Introduction
- •Structure, functions and methods of research of biological membranes The general structure of cell
- •Ultrastrucrure and function of function of biological membrane
- •Kinds of passive transport
- •Methods of research of structure and functions of biological membranes
- •Method of a dark field.
- •Phase - contrast method.
- •Ultramicroscopy.
- •Electronic microscopy.
- •Method of diffraction of X-rays radiation.
- •Luminescent methods of research of membranes.
- •Method of ultrachemistry.
- •Nuclear magnetic resonance research and electronic paramagnetic resonance research.
- •Research of forces of a superficial tension Properties of liquids
- •Superficial tension.
- •Physical properties of biological membranes.
- •Molecular mechanisms of electrochemical potentials of membranes and distribution of a nervous impulse along excitability fibre.
- •Principles of transformation of biological and not electric signals in electric. Designs of sensors and electrodes, their basic characteristics
- •Application of sensors
- •Analog registering devices
- •Rhythm of heart. Parameters of cardiac activity.
- •External displays of activity of heart.
- •Activity of heart
- •Electric activity of cells of a myocardium
- •Functions of conductive system of heart
- •The electrocardiogram
- •Change of a rhythm of cardiac activity.
- •The device and main principles of work of electrocardiograph
- •Imposing of electrodes
- •The device, a principle of work of electroencephalograph. Basic rhythms of eeg. Registration of eeg and principles of the analysis
- •Introduction
- •Essence of a method
- •Technique of record of electroencephalogram.
- •Principles of analyses of electroencephalogram
- •Definition of a photoeffect
- •Types of photoeffects.
- •Einstein equation
- •Application of a photo effect in medicine.
- •The device, principle of work spectrophotometer. Application spectrophometrical methods of research for definition of concentration of substances in biological liquids
- •Method of the calibre graph.
- •Method of comparison.
- •Polarization of light by biosystems. Polarimeter. Light natural and polarized. Polaroids.
- •Research of microstructures in polarizing light
- •Rotation of a plane of fluctuations of polarized light. Saccharimetry.
- •Design of the device
- •Principle of action
- •Special receptions of microscopy of biological objects Special methods of light microscopy (illumination and supervision). Method of a dark field.
- •Method of ultramicroscopy
- •Method of a light field and its version
- •Method of phase contrast
- •Polarizing microscopy
- •The method interference contrast
- •Method of research in a view of a luminescence
- •Device of a microscope. Measurement of value of microscoping object.
- •Model of sliding strings. Biomechanics of a muscle. The equation of Hill. Modeling of muscular reduction Biophysics of muscular reduction
- •Structure of a cross-section-striped muscle. Model of sliding strands.
- •Biomechanics of a muscle
- •The equation of Hill. Power of single reduction.
- •Modelling of muscular reduction
- •Electromechanical interface in muscles
- •Devices for measurement of function of external breath. The device and a principle of work. Registration and the analysis of the given functional researches
- •Change of saturation by gases of an organism at differences of external pressure.
- •Biomechanics of external breath
- •Devices for measurement of function of external breath
- •Viscosity of a liquid
- •Current of a liquid on a horizontal pipe. Puazal’s law.
- •Current of a liquid on a pipe of variable section and branched out
- •Definition of speed of blood-groove
- •Full resistance (impedance) of tissues of the organism Physical bases of rheography
- •Measurement of factor of viscosity.
- •Physical bases of hemodynamic. Laws of movement of blood in an arterial and venous channel
- •Measurement of pressure of blood
- •Systolic and minute volume of a blood-groove
- •Change of minute volume of a blood-groove at work.
- •Biophysical features of an aorta.
- •Biophysical features of arterioles of the big circle of blood circulation.
- •Tomographic methods
- •Classification of kinds of a tomography.
- •Interposition of a source of probing radiation, bject and the detector.
- •Echosounding
- •Computer tomograph.
- •Magnetic-resonant tomography.
- •Three-dimensional ultrasonic
- •ElastoScan-flexography
- •Modes of an acoustic transparency of three-dimensional ultrasonic.
- •Methods of physiotherapeutic influence
- •The therapeutic techniques based on application of a direct current. Electrophoresis and galvanizing in a medical practice. Mobility of ions.
- •Medicinal electrophoresis.
- •Galvanizing.
- •Electrosecurity
- •The basic requirements to an electrosecurity of electromedical devices and devices.
- •Modelling of biophysical processes.
- •The basic stages of modelling
- •The basic stages of modelling
- •4. Creation of model, its research.
- •Classification of models:
- •Mathematical models of growth of number of a population.
- •Pharmacokinetic model.
- •Sources of X-ray radiation.
- •Artificial sources of radiation.
- •Interaction of X-ray radiation with substance.
- •1. Coherent dispersion;
- •2. Photoeffect
- •3. Kompton - effect
- •Radioactivity radiation Radioactive disintegration Structure of a nucleus
- •A radioactive disintegration. Kinds of radioactive radiation
- •It is thrown out and a nucleus has more stability complex of nucleons. Positron β-disintegration is described by the equation:
- •The basic law of radioactive disintegration in the differential form. A constant of disintegration.
- •The basic law of radioactive disintegration in the differential form.
- •A half-life period.
- •Activity. A unit of measure.
- •Radioactive elements in the nature.
- •Ionizing radioactive radiation and its biological action.
- •The absorbed and exposition doze. Power of a doze. Units of measure.
- •Relative biological efficiency.
- •Mehanisms of action of laser radiation on biological tissues.
- •Mechanisms of action of laser radiation on biological tissues
- •Список использованной литературы :
- •Educational handout on medical biophysics kovaleva larissa valentinovna
Imposing of electrodes
Before imposing of electrodes the skin of the patient in places of contact is desirable for degreasing spirit.
Position of electrode |
Color |
Designation of an electrode |
right hand |
Red |
R |
left hand |
Yellow |
L |
right leg |
Black |
N |
left leg |
Green |
F |
As the current-carrying environment between electrodes and a skin of the patient it is necessary to apply electrode gels or pastes; use of the gauze linings moistened by physiological or a hypertonic solution or, as a last resort, by water is supposed.
Electrodes are imposed on extremities of the patient in conformity with the table 1.
On a thorax electrodes are imposed according to table 2.
Tap |
Position of electrode |
Designation of an electrode |
V1 |
In the fourth intercostals to the right of a sternum |
C1 |
V2 |
In the fourth intercostals to the left of a sternum |
C2 |
V3 |
On the fifth edge |
C3 |
V4 |
In the fifth intercostals on left clavicular lines |
C4 |
V5 |
At a level on a forward axillary line |
C5 |
V6 |
At a level on an average axillary line |
C6 |
Electrocardiograph provides registration of an electrocardiogram in various modes - automatic (synchronous registration of all of 12 assignments, preservation of an electrocardiogram in memory of the device, a press their groups on 3 assignments) or monitor (registration of an electrocardiogram in any chosen group of assignments without preservation in memory).
The device, a principle of work of electroencephalograph. Basic rhythms of eeg. Registration of eeg and principles of the analysis
Introduction
Method of registration of biological activity of a brain by means of record of biopotentials is called electroencephalography, corresponding devices is called electroencephalograph. Graph of dependence biopotentials upon time is called encephalogram (EEG). Electroencephalography gave chance of qualitative and quantitative analysis of a functional condition of a brain and its reactions at action of irritant.
Character EEG is defined by a functional condition of a nervous tissue, a level of exchange processes proceeding in it. Infringement of blood supply, hypoxia or a deep narcosis lead to suppression of bioelectric activity of a cortex of cerebrum. Dependence EEG upon the general condition of an organism widely is used in clinic. Method of EEG of research of a brain is the most perspective modern method. EEG has the features, has spontaneous, independent character. Regular electric activity of a brain can be fixed already at a foetus (i.e. till a birth of an organism) and stops only with approach of death. Even at deep coma and a narcosis the characteristic picture of brain waves is observed.
Character of bioelectric activity depends upon receipt of a nervous pulsation on specific channels from touch system, and also from subcortical formations (reticular formations of a trunk of a brain and thalamus).
Electroencephalography is used for revealing volumetric, inflammatory and vascular processes of a brain, specification of localization of the pathological centers, for diagnostic of pathologies of nervous system: traumas and a heart attack of a brain, infringement of a dream, mental frustration. Record EEG is widely applied in diagnostic and medical work (it is especially frequent at epilepsy). EEG is applied in anesthesiology, at studying activity of the brain connected with realization of following functions: perception, memory, adaptation.
Electroencephalography is applied for determination areas of a tumor of a brain, to an estimation of a functional condition of a brain before introduction of a medical product.
EEG reflects integrated activity of huge number neurons of brain cortex and distribution of waves of excitation to neural networks.
The analysis of electroencephalogram is complex and demands participation of neurophysiologist, possessing the practical experience, owning and neurological semiotics.
To expand opportunities of electroencephalography, computer processing of electroencephalogram helps.
