Vitamins

1. A 64 year old woman suffers from night blindness (hemeralopia). What vitamin drug should be recommended?

A. * Retinolum

B. Riboflavin

С. Tocopherolum

D. Pyridoxinum

E. Ascorbic acid

2. A 58 year old woman suffers from cerebral atherosclerosis. Complex of her pharmacotherapy includes drug of vitamin E & С. Which pharmacological effect of these drugs is the main for treatment of this disease?

A. * Inhibition of free-radical oxidation of lipids

B. Increase of gonadotropic hormones synthesis in the pituitary body

С. Decrease of glucocorticoids release by adrenals

D. Strengthening of the antitoxic function of the liver

E. Improvement of the coronary circulation

3. A patient who had been taking л vitamin drug for the prevention of cerebrovascular spastic reactions began to complain of unpleasnt feelings: hyperemia of the face and upper part of the body, vertigo, feeling of blood influx into the head. What drug may cause these side-effects

A. *Nicotinic acid

В. Tocopheroli acetas

C. Nicotinamidum

D. Thiamin/ bromidum

E. Calcii pangamas

4. A patient had been taking vitamin D for a long time for treatment of rickets. Soon the signs of vitamin D intoxication developed: loss of appetite, nausea, headache, fatigue, increase of body temperature, etc. What vitamin decreasing the toxic influence of vitamin D should be administered?

A *Vitamin A

B. Vitamin С

C. Vitamin В₁₂

D. Vitamin PP

E. Vitamin B₂

5. A 55 year old patient was admitted to the haemotological department with signs of acute anemia. After laboratory examination megaloblastic hyperchromic anemia was diagnosed, which drug must be administered to the patient first of all?

A. *Cyanocobalaminum

B. Hemostimulinum

C. Ferroplexum

D. Ferrum-Lek

E. Folic acid

6. A 55 year old patient suffering from hyperchromic anemia obtained long-term treatment with vitamin В₁₂ parenterally. Why the parenteral way of introduction of vitamin B₁₂ is prefered more than the peroral way?

A.*It isn't absorbed in the intestine in oral introduction due to deficit of gastromucoproiein

B. It is faster absored

С It is longer circulated in the blood

D. It is faster penetrated to the bone marrow

E. it isn't destroied in the liver

7. A patient has diarrhoea, dementia and dermatitis. What vitamin has to be included into the complex pharmacotherapy?

A. *Nicotinic acid

B. Thiaminum

C. Cyanocobalaminum

D. Panthotenic acid

E. Riboflavinum

8.There is an inhibited coagulation in the patient with bile ducts obstruction, bleeding due to the low level of absorbtion of a vitamin. What vitamin is in deficiency?

A. *Vitamin К

B. Vitamin D

С. Carotene

D. Vitamin A

E. Vitamin E.

9. A patient with diabetes mellitus is treated by injections of vitamin B1 to eliminate metabolic acidosis. Which biochemical mechanism of action of vitamin B1 ensures the positive effect?

A. * Activation of dehydrogenases of the Krebs cycle

B. Activation of adenylate cyclase

С. Blockade or phosphodiesterase

D. Acceleration of acetylcholine synthesis

E. Acceleration of adrenaline synthesis

10. Metabolic acidosis arose in a patient due to impairment of carbohy­drate metabolism and accumulation of ketoacids in the organism, indicate the vitamin drug which promotes its elimination due to decrease concentration of ketoacids.

A. *Thiamine

B. Pyridoxins

С. Folic acid

D. Riboflavine

E. Ascorbic acid

11. A patient suffers from chronic alcoholism with the following symptoms: pain in arms and legs, impairment of skin sensitivity, muscle weakness, edemas and increased amount of pyruvate. Which vitamin drug should be prescribed to the patient?

A. * Thiamine

B. Ergocalciferol

C. Retinol

D. Rutin

E. Vikasoium (Menadione)

12. 55 years old patient was admitted to the hematological department with acute anemia: RBCs - 1,5 x 10¹²/litre; Hb - 80g%, colour index - 1,3. Hyperchromic anemia was diagnosed. Which drug should be administered for treatment of this disease?

A. *Cyanocobalamine

B. Ferroplexum

С. Hemostimuline

D. Ferrum-lek

E. Folic acid

13.Which of the acids below decreases permeability of connective tissue structures, possesses antioxidant activity due to ability to be transformed from the oxydized form into reduced and on the contrary?

A. * Ascorbic acid

B. Hydrochloric acid

C. Mefenamic acid

D. Aspirin (acetylsalicylic acid)

E. Aminocaproic acid

14. For synthesis of the basic substances of connective tissue (mucopolysaccharides and collagen) an essential agent is:

A. * Ascorbic acid

B. Nicotinic acid

С. Folic acid

D. Salicylic acid

E. Acetylsalicylic acid

15. Radiation therapy is performed to the patient. What vitamin drug with antioxidant properties is necessary for administration to increase stability of tissues in this case?

A. * Ascorutinum

B. Vitamin B₆

С Thiamine chloride

D. Cyanocobaiamine

E. Folic acid

16. The woman of 25 years who anted to get thin was on a diet hich consisted of 2 cups of coffee ithout sugar, 3 crackers from white bread, 2 sausages or 2 eggs in a day within 1,5 months. The mass of a body has dropped on 5 kg, but there were developed strong headaches, often nasal bleedings, bleeding, sickness of gums, shaking of teeth, -.helling of sfcin and shedding of hair.What vitamin drug is expedient in this (ase?

A. *Ascorbic acid

B. Folic acid

C. Retinol acetate

D. Cyancobalamine

E. Vikasolum (Menadione)

17. The patient who was treated by a vitaminic drug for prophylaxis of vasospasms of the brain, has developed complaints of the unpleasant sensations related to taking of this medicine: reddening of the face and the upper half of a trunk, giddiness, sence of flush of blood to a head. For what drug the specified side-effects are characteristic?

A. *'Nicotinic acid

B. Nicotinamidum

C. Thiamine bromide

D. Tocoferol acetate

E. Calcium pangamate

18. Bioflavonoids (rutin, quercetin) possess all listed below pharmacodynamic effects, except for:

A. * Dilation of capillaries

B. Antioxidant activity

C. Inhibition of hyaluronidase activity

D. Decrease of permeability of capillary wall

E. Protections of ascorbic acid, assistance to its transport and accumulation

19. 64 years old woman suffers from hemeralopia (disturbance of vision in darkness). What vitaminic drug should be recommended her first of all?

A. *Retinoli acetate

B. Tocoferol acetate

C. Pyridoxin

D. Ascorbic acid

E. Riboflavin

20. What vitamin promotes growth and development of epithelial cells, including epidermal ones?

A. *Retinol

B. Ergocalciferol

C. Ascorbic acid

D. Nicotinic acid

E. Lipoic acid

21. 39 years old patient suffers from hyperkeratosis, disturbance of vision in darkness, frequent infectious diseases. What vitaminic drug should be administered for treatment .

A. *Retinol acetate

B. Pyridoxin

С. Riboflavin

D. Ergocalciferol

E. Tocoferol acetate

22. What vitamin is formed in skin under influence of ultraviolet radiation?

1. *Cholecalciferol

2. Ascorbinic acid

3. Retinole acetate

4. Calcium pantotenate

5. Riboflavin

23. To the child with signs of rachitis the pediatrist and the "dentist administered a liposoluble vitamin which influences an exchange of phosphorus and calcium in an organism, promotes sedimentation of calcium in bone tissue and dentins. Determine a drug.

A. *Ergocalciferol

B. Tocoferol acetate

С. Retinoli acetate

D. Vikasolum (Menadione)

E. Thyreoidinum

24. Parasthesia, xeroderma arid sticking out of fontanel are observsed at the 6 months child under the treatment by a vitaminic drug. Specify this drug.

A. *Ergocalciferol

B. Pyridoxine

С. Riboflavin

D. Retinoli acetate

E. Tocoferol acetate

25. The dentist administered to his patient liposoluble vitamin with antioxidant activity for treatment of parodontitis. Specify this vitaminic drug.

A. * Tocoferol acetate

B. Ascorbic acid

C. Rutin

D. Nicotinic acid

E. Ergocalciferol

26.A doctor administered tocoferol acetate to a patient with ischemic heart disease. What effect of a drug does the doctor expect?

A. *Antioxidant

B. Spasmolytic

С. Hypotensive

D. Increase of oxygen delivery to myocardium

E. Positive inotropic

27. What enzymatic drug is used with the purpose of dropping of density and rising of permeability of connective tissue structures?

A. *Lidase

B. Lipase

С. Cocarboxylase

D. Cholines terase

E. Amylase

28. In order to accelerate healing of a radiation ulcer a vitamin drug was administered. What drug is it?

A *Retinol acetate

B Retabolil

C Prednisolone

D Levamisole

E Methyluracil

29. A 64 year old woman has impairment of twilight vision (hemeralopy). What vitamin should be recommended in the first place?

A *Vitamin A

B Vitamin B2

C Vitamin E

D Vitamin C

E Vitamin B6

30. A patient presents with twilight vision impairment. Which of the following vitamins should be administered?

A *Retinol acetate

B Cyanocobalamin

C Pyridoxine hydrochloride

D Ascorbic acid

E Nicotinic acid

31. A patient suffers from vision impairment - hemeralopy (night blindness). What vitamin preparation should be administered the patient in order to restore his vision?

A *Retinol acetate

B Vicasol

C Pyridoxine

D Thiamine chloride

E Tocopherol acetate