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18. Read and translate the text. Make a summary: examination of the newborn

The initial examination should be performed as soon as possible after delivery to detect abnormalities and to establish a baseline for subsequent examination. This examination should take place in the delivery room. A second and more detailed examination is performed within 24 hours after birth. No infant should be discharged from the hospital without final examination.

Стр.96-97

  1. Read text IX and write out Key-sentences from each passage:

Text IX. Allergies in the So-Called Allergic Person with Excess IgE Antibodies

Some people have an “allergic” tendency. Their allergies are called atopic allergies because they are caused by a nonordinary response of the immune system. The allergic tendency is genetically passed on from parent to child and is characterized by the presence of large quantities of IgE antibodies. These antibodies are called regains or sensitizing antibodies to distinguish them from the more common IgG antibodies. When an allergen (defined as an antigen that reacts specifically with a specific type of IgE regain antibody) enters the body, an allergen-reagin reaction takes place and a subsequent allergic reaction takes place.

A special characteristic of the IgE antibodies (the regains) is a strong propensity to attach to mast cells and basophils. Indeed, a single mast cell or basophil can bind as many as half a million molecules of IgE antibodies. Then, when an antigen (an allergen) that has multiple binding sites binds with several of the IgE antibodies attached to a mast cell or basophil, this causes an immediate change in the membrane of the cell, perhaps resulting from a simple physical effect of the antibody molecules being pulled together by the antigen. At any rate, many of the mast cells and basophils rupture; others release their granules without rupturing and secrete additional substances not already preformed in the granules. Some of the many substances that are either released immediately or secreted shortly thereafter include histamine, slow-reacting substance of anaphylaxis (which is a mixture of toxic leukotrienes), eosinophil chemotactic substance, a protease, a neutrophil chemotactic substance, heparin, and platelet activating factors. These substances cause such phenomena as dilatation of the local blood vessels, attraction of eosinophils and neutrophils to the reactive site, damage to the local tissues by the protease, increased permeability of the capillaries and loss of fluid into the tissues, and contraction of local smooth muscle cells. Therefore, a number of different types of abnormal tissue responses can occur, depending on the type of tissue in which the allergen-reagin reaction occurs. Among the different types of allergic reactions caused in this manner are the following:

Anaphylaxis. When a specific allergen is injected directly into the circulation, it can react in widespread areas of the body with the basophils of the blood and the mast cells located immediately outside the small blood vessels if these have been sensitized by attachment of IgE regains. Therefore, a widespread allergic reaction occurs throughout the vascular system and in closely associated tissues. This is called anaphylaxis. The histamine released into the circulation causes body-wide vasodilatation as well as increased permeability of the capillaries with resultant marked loss of plasma from the circulation. Many people who experience this reaction die of circulatory shock within a few minutes unless they are treated with epinephrine to oppose the effects of the histamine. But also released from the cells is a mixture of leukotrienes, which are also called slow-reacting substance of .anaphylaxis. These leukotrienes cause spasm of the smooth muscle of the bronchioles, eliciting an asthma-like attack and sometimes causing death by suffocation.

Urticaria. Urticaria results from antigen entering specific skin areas and causing localized anaphylactoid reactions. Histamine released locally causes (1) vasodilatation that induces an immediate red flare and (2) increased local permeability of the capillaries that leads to local circumscribed areas of swelling of the skin in another few minutes. The swellings are commonly called hives. Administration of antihistamine drugs to a person before exposure will prevent the hives.

Hay Fever. In hay fever, the allergen-reagin reaction occurs in the nose. Histamine released in response to the reaction causes local vascular dilatation, with resultant increased capillary pressure, as well as increased capillary permeability. Both of these effects cause rapid fluid leakage into the tissues of the nose, and the nasal linings become swollen and secretory. Here again, use of antihistamine drugs can prevent this swelling reaction. Other products of the

food-upset

расстройство пищеварения

enuresis

недержание мочи

to guide away

увести, отвести, отвлечь

excessive irritation

чрезмерное раздражение

cutaneous eruption, exanthema

кожная сыпь

  1. Translate the word combinations with the given key-words:

allergy: allergy pediatric clinic; respiratory allergy; allergy history; allergy management; severe allergy

allergic: allergic symptoms; allergic disease; allergic condition; allergic manifestations; allergic factor; allergic response; allergic test; allergic asthma; an allergic attack

asthmatic: asthmatic children; asthmatic condition; asthmatic breathing; asthmatic attacks; an asthmatic

sensitivity: increased sensitivity; lowered sensitivity; abnormal sensitivity; unusual sensitivity; specific sensitivity; food sensitivity

Стр.86-87

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