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Preface

The healing process in children and adolescents with oncological diseases depends greatly on the knowledge and experience of all those involved in the patients’ care: physicians, specialist nurses, psychooncologists and others. This last group embraces parents, siblings and teachers as well as laboratory staff, physiotherapists, chaplains, social workers and other hospital personnel. Increasingly, the patients’ general practitioners and pediatricians and external nurses are also becoming involved. Knowledge and experience on the part of the carers are necessary for full information of the patient, who is thus enabled to play a full part in his or her own healthcare: the power of the informed patient. Whether a young patient is waiting for the diagnosis, undergoing intensive therapy, or suffering a complication or setback, whether he/she knows that the disease has almost certainly been healed or that it is progressing with early death as the probable consequence – in every situation, full information is the basis of optimal care.

This book was written to improve the fundamental dissemination of knowledge. It has no pretensions to replace the standard textbooks and the journals regarding pediatric oncology.

In this second edition the chapters systematically describe the various disease groups. The content is adapted by new findings within the last 5 years. Some of these chapters were written by Thomas Kühne, for many years my trusted colleague. Robert Arceci of Johns Hopkins, Baltimore, editor-in-chief of “Pediatric Blood and Cancer,” brought his vast experience to bear on the English translation.

My heartfelt thanks go to all of the contributing authors and to the responsible staff at Springer Heidelberg for their commitment to this project.

May this book help to create an atmosphere of trust, hope and joy in the face of potentially life-threatening disease.

Basel

Paul Imbach

2005/2011

 

vii

Contents

1

General Aspects of Childhood Leukemia .............................................

1

 

Paul Imbach

 

2

Acute Lymphoblastic Leukemia ............................................................

5

 

Paul Imbach

 

3

Acute Myeloid Leukemia........................................................................

21

 

Paul Imbach

 

4

Myelodysplastic Syndrome.....................................................................

35

 

Thomas Kühne

 

5

Myeloproliferative and Myelodysplastic/Myeloproliferative

 

 

Neoplasms ................................................................................................

43

 

Thomas Kühne

 

6

Non-Hodgkin Lymphoma.......................................................................

53

 

Paul Imbach

 

7

Hodgkin Disease......................................................................................

63

 

Paul Imbach

 

8

Histiocytoses ............................................................................................

75

 

Paul Imbach

 

9

Brain Tumors...........................................................................................

89

 

Paul Imbach

 

10

Neuroblastoma ........................................................................................

113

 

Paul Imbach

 

11

Nephroblastoma (Wilms Tumor)...........................................................

125

 

Paul Imbach

 

12

Soft Tissue Sarcoma................................................................................

135

 

Paul Imbach

 

13

Osteosarcoma ..........................................................................................

155

 

Thomas Kühne

 

ix

x

 

Contents

14

Ewing Sarcoma Family of Tumors ........................................................

161

 

Thomas Kühne

 

15

Retinoblastoma........................................................................................

167

 

Paul Imbach

 

16

Germ Cell Tumors ..................................................................................

175

 

Paul Imbach

 

17

Hepatic Tumors.......................................................................................

185

 

Paul Imbach

 

18

Emergencies in Pediatric Oncology.......................................................

191

 

Thomas Kühne

 

19

Oncological Nursing Care ......................................................................

203

 

Franziska Oeschger-Schürch and Christine Verdan

 

20

Psychology and Psychosocial Issues in Children with Cancer............

225

 

Alain Di Gallo and Kerstin Westhoff

 

Index.................................................................................................................

241

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