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Contents · XI

9 Cerebrum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

350

Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350

Gross Anatomy and Subdivision of the Cerebrum . . . . . . . . . . . . . . . . . . . 354

Gyri and Sulci . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354

Histological Organization of the Cerebral Cortex . . . . . . . . . . . . . . . . . . . . 358

Laminar Architecture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359

Cerebral White Matter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365

Projection Fibers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365

Association Fibers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366

Commissural Fibers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366

Functional Localization in the Cerebral Cortex . . . . . . . . . . . . . . . . . . . . . . 369 Primary Cortical Fields . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371 Association Areas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384 Frontal Lobe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386 Higher Cortical Functions and Their Impairment by Cortical Lesions . . . . 386

10 Coverings of the Brain and Spinal Cord; Cerebrospinal Fluid and Ventricular System . . . . . . 402

Coverings of the Brain and Spinal Cord . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402

Dura Mater . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402

Arachnoid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405

Pia Mater . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406

Cerebrospinal Fluid and Ventricular System . . . . . . . . . . . . . . . . . . . . . . . . . 406

Structure of the Ventricular System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406

Cerebrospinal Fluid Circulation and Resorption . . . . . . . . . . . . . . . . . . . . . . . . 406

Disturbances of Cerebrospinal Fluid Circulation—Hydrocephalus . . . . . . . 411

11 Blood Supply and Vascular Disorders

of the Central Nervous System . . . . . . . . . . . . . . . . . . . . . . 418

Arteries of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419 Extradural Course of the Arteries of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . 419 Arteries of the Anterior and Middle Cranial Fossae . . . . . . . . . . . . . . . . . . . . 421 Arteries of the Posterior Fossa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 Collateral Circulation in the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432

Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.

XII · Contents

Veins of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435

Superficial and Deep Veins of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435

Dural Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437

Blood Supply of the Spinal Cord . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439

Arterial Anastomotic Network . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439

Venous Drainage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442

Cerebral Ischemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 Arterial Hypoperfusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 Particular Cerebrovascular Syndromes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463 Impaired Venous Drainage from the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473

Intracranial Hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477

Intracerebral Hemorrhage (Nontraumatic) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 478

Subarachnoid Hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481

Subdural and Epidural Hematoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487

Vascular Syndromes of the Spinal Cord . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489

Arterial Hypoperfusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489

Impaired Venous Drainage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 490

Spinal Cord Hemorrhage and Hematoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492

Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 493

Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

497

Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.

· XIII

Abbreviations

5-HT3

serotonin

ACTH

adrenocorticotropic hormone (corticotropin)

AIDS

acquired immunodeficiency syndrome

AMPA

α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate acid

ARAS

ascending reticular activating system

BAEP

brainstem auditory evoked potentials

BPPV

benign paroxysmal positioning vertigo

CNS

central nervous system

CRF

corticotropin-releasing factor

CSF

cerebrospinal fluid

CT

computed tomography

DREZ

dorsal root entry zone (also called the Redlich-Obersteiner zone)

ECG

electrocardiography/electrocardiogram

EEG

electroencephalography/electroencephalogram

EMG

electromyography/electromyogram

EPSP

excitatory postsynaptic potential

FLAIR

fluid-attenuated inversion recovery

fMRI

functional magnetic resonance imaging

FSH

follicle-stimulating hormone

GABA

γ-aminobutyric acid

GH (STH)

growth hormone (somatotropic hormone)

GHRH

growth-hormone-releasing hormone

GnRH

gonadotropin-releasing hormone

HIV

human immunodeficiency virus

HMSN

hereditary motor and sensory polyneuropathy

INO

internuclear ophthalmoplegia

IP

interphalangeal

IPSP

inhibitory postsynaptic potential

LH

luteninizing hormone

LPH

lipotropin

LTM

long-term memory

MEG

magnetoencephalography

MIF

melanocyte-stimulating hormone-inhibiting factor

MLF

medial longitudinal fasciculus

MP

metacarpophalangeal

MRF

melanocyte-stimulating hormone-releasing factor

MRI

magnetic resonance imging

Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.

XIV · Abbreviations

MSH

melanocyte-stimulating hormone

NMDA

N-methyl-D-aspartate

PET

positron emission tomography

PICA

posterior inferior cerebellar artery

PIF

prolactin-inhibiting factor (= dopamine)

PPRF

paramedian pontine reticular formation

PRF

prolactin-releasing factor

PRL

prolactin

rCBF

regional cerebral blood flow

SCD

subacute combined degeneration

SRIF

somatotropin inhibiting factor

STM

short-term memory

T3

triiodothyronine

T4

tetraiodothyronine (thyroxine)

TRH

thyrotropin-releasing hormone

TSH

thyroid-stimulating hormone

VEP

visual evoked potentials

VOR

vestibulo-ocular reflex

VPL

ventral posterolateral nucleus of the thalamus

VPM

ventral posteromedial nucleus of the thalamus

Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.

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