- •Preface
- •Contents
- •1 Elements of the Nervous System
- •2 Somatosensory System
- •3 Motor System
- •4 Brainstem
- •5 Cerebellum
- •6 Diencephalon and Autonomic Nervous System
- •7 Limbic System
- •8 Basal Ganglia
- •9 Cerebrum
- •10 Coverings of the Brain and Spinal Cord; Cerebrospinal Fluid and Ventricular System
- •Further Reading
- •Index
- •Abbreviations
- •1 Elements of the Nervous System
- •Elements of the Nervous System
- •Information Flow in the Nervous System
- •Synapses
- •Neurotransmitters and Receptors
- •Functional Groups of Neurons
- •Glial Cells
- •Development of the Nervous System
- •2 Somatosensory System
- •Peripheral Nerve, Dorsal Root Ganglion, Posterior Root
- •Peripheral Regulatory Circuits
- •Central Components of the Somatosensory System
- •Posterior and Anterior Spinocerebellar Tracts
- •Posterior Columns
- •Anterior Spinothalamic Tract
- •Lateral Spinothalamic Tract
- •Other Afferent Tracts of the Spinal Cord
- •Central Processing of Somatosensory Information
- •Somatosensory Deficits due to Lesions at Specific Sites along the Somatosensory Pathways
- •3 Motor System
- •Central Components of the Motor System and Clinical Syndromes of Lesions Affecting Them
- •Motor Cortical Areas
- •Corticospinal Tract (Pyramidal Tract)
- •Corticonuclear (Corticobulbar) Tract
- •Other Central Components of the Motor System
- •Lesions of Central Motor Pathways
- •Peripheral Components of the Motor System and Clinical Syndromes of Lesions Affecting Them
- •Clinical Syndromes of Motor Unit Lesions
- •Complex Clinical Syndromes due to Lesions of Specific Components of the Nervous System
- •Spinal Cord Syndromes
- •Vascular Spinal Cord Syndromes
- •Nerve Root Syndromes (Radicular Syndromes)
- •Plexus Syndromes
- •Peripheral Nerve Syndromes
- •Syndromes of the Neuromuscular Junction and Muscle
- •4 Brainstem
- •Surface Anatomy of the Brainstem
- •Medulla
- •Pons
- •Midbrain
- •Olfactory System (CN I)
- •Visual System (CN II)
- •Eye Movements (CN III, IV, and VI)
- •Trigeminal Nerve (CN V)
- •Facial Nerve (CN VII) and Nervus Intermedius
- •Vagal System (CN IX, X, and the Cranial Portion of XI)
- •Hypoglossal Nerve (CN XII)
- •Topographical Anatomy of the Brainstem
- •Internal Structure of the Brainstem
- •5 Cerebellum
- •Surface Anatomy
- •Internal Structure
- •Cerebellar Cortex
- •Cerebellar Nuclei
- •Connections of the Cerebellum with Other Parts of the Nervous System
- •Cerebellar Function and Cerebellar Syndromes
- •Vestibulocerebellum
- •Spinocerebellum
- •Cerebrocerebellum
- •Cerebellar Tumors
- •6 Diencephalon and Autonomic Nervous System
- •Location and Components of the Diencephalon
- •Functions of the Thalamus
- •Syndromes of Thalamic Lesions
- •Thalamic Vascular Syndromes
- •Epithalamus
- •Subthalamus
- •Hypothalamic Nuclei
- •Afferent and Efferent Projections of the Hypothalamus
- •Functions of the Hypothalamus
- •Sympathetic Nervous System
- •Parasympathetic Nervous System
- •Visceral and Referred Pain
- •7 Limbic System
- •Anatomical Overview
- •Internal and External Connections
- •Microanatomy of the Hippocampal Formation
- •Amygdala
- •Functions of the Limbic System
- •Types of Memory
- •8 Basal Ganglia
- •Preliminary Remarks on Terminology
- •The Role of the Basal Ganglia in the Motor System: Phylogenetic Aspects
- •Connections of the Basal Ganglia
- •Function and Dysfunction of the Basal Ganglia
- •Clinical Syndromes of Basal Ganglia Lesions
- •9 Cerebrum
- •Development
- •Gross Anatomy and Subdivision of the Cerebrum
- •Gyri and Sulci
- •Histological Organization of the Cerebral Cortex
- •Laminar Architecture
- •Cerebral White Matter
- •Projection Fibers
- •Association Fibers
- •Commissural Fibers
- •Functional Localization in the Cerebral Cortex
- •Primary Cortical Fields
- •Association Areas
- •Frontal Lobe
- •Coverings of the Brain and Spinal Cord
- •Dura Mater
- •Arachnoid
- •Pia Mater
- •Cerebrospinal Fluid Circulation and Resorption
- •Arteries of the Anterior and Middle Cranial Fossae
- •Arteries of the Posterior Fossa
- •Collateral Circulation in the Brain
- •Dural Sinuses
- •Venous Drainage
- •Cerebral Ischemia
- •Arterial Hypoperfusion
- •Particular Cerebrovascular Syndromes
- •Impaired Venous Drainage from the Brain
- •Intracranial Hemorrhage
- •Intracerebral Hemorrhage (Nontraumatic)
- •Subarachnoid Hemorrhage
- •Subdural and Epidural Hematoma
- •Impaired Venous Drainage
- •Spinal Cord Hemorrhage and Hematoma
- •Further Reading
- •Index
Contents · XI
9 Cerebrum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
350 |
Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 350
Gross Anatomy and Subdivision of the Cerebrum . . . . . . . . . . . . . . . . . . . 354
Gyri and Sulci . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 354
Histological Organization of the Cerebral Cortex . . . . . . . . . . . . . . . . . . . . 358
Laminar Architecture . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359
Cerebral White Matter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365
Projection Fibers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365
Association Fibers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366
Commissural Fibers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 366
Functional Localization in the Cerebral Cortex . . . . . . . . . . . . . . . . . . . . . . 369 Primary Cortical Fields . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 371 Association Areas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 384 Frontal Lobe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386 Higher Cortical Functions and Their Impairment by Cortical Lesions . . . . 386
10 Coverings of the Brain and Spinal Cord; Cerebrospinal Fluid and Ventricular System . . . . . . 402
Coverings of the Brain and Spinal Cord . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402
Dura Mater . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 402
Arachnoid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405
Pia Mater . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406
Cerebrospinal Fluid and Ventricular System . . . . . . . . . . . . . . . . . . . . . . . . . 406
Structure of the Ventricular System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 406
Cerebrospinal Fluid Circulation and Resorption . . . . . . . . . . . . . . . . . . . . . . . . 406
Disturbances of Cerebrospinal Fluid Circulation—Hydrocephalus . . . . . . . 411
11 Blood Supply and Vascular Disorders
of the Central Nervous System . . . . . . . . . . . . . . . . . . . . . . 418
Arteries of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419 Extradural Course of the Arteries of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . 419 Arteries of the Anterior and Middle Cranial Fossae . . . . . . . . . . . . . . . . . . . . 421 Arteries of the Posterior Fossa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 427 Collateral Circulation in the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 432
Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
XII · Contents
Veins of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435
Superficial and Deep Veins of the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435
Dural Sinuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437
Blood Supply of the Spinal Cord . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439
Arterial Anastomotic Network . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439
Venous Drainage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442
Cerebral Ischemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 Arterial Hypoperfusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443 Particular Cerebrovascular Syndromes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 463 Impaired Venous Drainage from the Brain . . . . . . . . . . . . . . . . . . . . . . . . . . . . 473
Intracranial Hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 477
Intracerebral Hemorrhage (Nontraumatic) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 478
Subarachnoid Hemorrhage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481
Subdural and Epidural Hematoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 487
Vascular Syndromes of the Spinal Cord . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489
Arterial Hypoperfusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489
Impaired Venous Drainage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 490
Spinal Cord Hemorrhage and Hematoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492
Further Reading . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 493
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
497 |
Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
· XIII
Abbreviations
5-HT3 |
serotonin |
ACTH |
adrenocorticotropic hormone (corticotropin) |
AIDS |
acquired immunodeficiency syndrome |
AMPA |
α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate acid |
ARAS |
ascending reticular activating system |
BAEP |
brainstem auditory evoked potentials |
BPPV |
benign paroxysmal positioning vertigo |
CNS |
central nervous system |
CRF |
corticotropin-releasing factor |
CSF |
cerebrospinal fluid |
CT |
computed tomography |
DREZ |
dorsal root entry zone (also called the Redlich-Obersteiner zone) |
ECG |
electrocardiography/electrocardiogram |
EEG |
electroencephalography/electroencephalogram |
EMG |
electromyography/electromyogram |
EPSP |
excitatory postsynaptic potential |
FLAIR |
fluid-attenuated inversion recovery |
fMRI |
functional magnetic resonance imaging |
FSH |
follicle-stimulating hormone |
GABA |
γ-aminobutyric acid |
GH (STH) |
growth hormone (somatotropic hormone) |
GHRH |
growth-hormone-releasing hormone |
GnRH |
gonadotropin-releasing hormone |
HIV |
human immunodeficiency virus |
HMSN |
hereditary motor and sensory polyneuropathy |
INO |
internuclear ophthalmoplegia |
IP |
interphalangeal |
IPSP |
inhibitory postsynaptic potential |
LH |
luteninizing hormone |
LPH |
lipotropin |
LTM |
long-term memory |
MEG |
magnetoencephalography |
MIF |
melanocyte-stimulating hormone-inhibiting factor |
MLF |
medial longitudinal fasciculus |
MP |
metacarpophalangeal |
MRF |
melanocyte-stimulating hormone-releasing factor |
MRI |
magnetic resonance imging |
Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
XIV · Abbreviations
MSH |
melanocyte-stimulating hormone |
NMDA |
N-methyl-D-aspartate |
PET |
positron emission tomography |
PICA |
posterior inferior cerebellar artery |
PIF |
prolactin-inhibiting factor (= dopamine) |
PPRF |
paramedian pontine reticular formation |
PRF |
prolactin-releasing factor |
PRL |
prolactin |
rCBF |
regional cerebral blood flow |
SCD |
subacute combined degeneration |
SRIF |
somatotropin inhibiting factor |
STM |
short-term memory |
T3 |
triiodothyronine |
T4 |
tetraiodothyronine (thyroxine) |
TRH |
thyrotropin-releasing hormone |
TSH |
thyroid-stimulating hormone |
VEP |
visual evoked potentials |
VOR |
vestibulo-ocular reflex |
VPL |
ventral posterolateral nucleus of the thalamus |
VPM |
ventral posteromedial nucleus of the thalamus |
Baehr, Duus' Topical Diagnosis in Neurology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.