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Table 13.2 (Continued)
No. Generic name Trade name Disease Year Source
540 Tiotropium bromide Spiriva COPD 2002 Natural product pharmacophore
541 Atazanavir Reyataz Antiviral 2003 Natural product pharmacophore
542 Atomoxetine Strattera ADHD 2003 Natural product pharmacophore
543 Fosamprenevir Lexiva Antiviral 2003 Natural product pharmacophore
544 Palonosetron Aloxi Antiemetic 2003 Natural product pharmacophore
545 Pitavastatin Livalo Hypocholesterolemic 2003 Natural product pharmacophore
546 Rosuvastatin Crestor Hypocholesterolemic 2003 Natural product pharmacophore
547 Tadalafil Cialis Male sexual dysfunction 2003 Natural product pharmacophore
548 Vardenafil Levitra Male sexual dysfunction 2003 Natural product pharmacophore
549 Abarelix Plenaxis Anticancer 2004 Natural product pharmacophore
550 Indisetron hydrochloride Sinseron Antiemetic 2004 Natural product pharmacophore
551 Pemetrexed disodium Alimta Anticancer 2004 Natural product pharmacophore
552 Tamibarotene Amnoid Anticancer 2005 Natural product pharmacophore
553 Tipranavir Aptivus Antiviral 2005 Natural product pharmacophore
554 Udenafil Zydena Male sexual dysfunction 2005 Natural product pharmacophore
555 Favipiravir Avigan Antiviral 2006 Natural product pharmacophore
556 Vorinostat Zolinza Anticancer 2006 Natural product pharmacophore
557 Aliskiren fumarate Tekturna Antihypertensive 2007 Natural product pharmacophore
558 Arformoterol tartrate Brovana COPD 2007 Natural product pharmacophore
559 Alvimopan hydrate Entereg Irritable bowel syndrome 2008 Natural product pharmacophore
560 Dabigatran etexilate Pradaxa Anticoagulant 2008 Natural product pharmacophore
561 Lacosamide Vimpat Antiepileptic 2008 Natural product pharmacophore
562 Rivaroxaban Xarelto Venous thromboembolism 2008 Natural product pharmacophore
563 Degarelix Firmagon Anticancer 2009 Natural product pharmacophore
564 Indacaterol maleate Onbrez COPD 2009 Natural product pharmacophore
565 Apixaban Eliquis Anticoagulant 2011 Natural product pharmacophore
566 Avanafil Zepeed Male sexual dysfunction 2011 Natural product pharmacophore
567 Boceprevir Victrelis Antiviral 2011 Natural product pharmacophore
568 Crizotinib Xalkori Anticancer 2011 Natural product pharmacophore
569 Edoxaban tosilate Lixiana Anticoagulant 2011 Natural product pharmacophore
570 Mirabegron Betanis Urinary incontinence 2011 Natural product pharmacophore
352 Chapter 13
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571 Ruxolitinib phosphate Jakafi Anticancer 2011 Natural product pharmacophore
572 Telaprevir Incivek Antiviral 2011 Natural product pharmacophore
573 Ticagrelor Britique Antithrombotic 2011 Natural product pharmacophore
574 Vandetanib Caprelsa Anticancer 2011 Natural product pharmacophore
575 Vemurafenib Zeboraf Anticancer 2011 Natural product pharmacophore
576 Axitinib Inlyta Anticancer 2012 Natural product pharmacophore
577 Bosutiniib Bosulif Anticancer 2012 Natural product pharmacophore
578 Cabozantinib S-malate Cometriq Anticancer 2012 Natural product pharmacophore
579 Dapagliflozin Forxiga Antidiabetic 2012 Natural product pharmacophore
580 Peginesatide Omontys Anemia 2012 Natural product pharmacophore
581 Radotinib Supect Anticancer 2012 Natural product pharmacophore
582 Regorafenib Stivarga Anticancer 2012 Natural product pharmacophore
583 Teriflunomide Aubagio Multiple sclerosis 2012 Natural product pharmacophore
584 Tofacitinib Xeljanz Antiarthritic 2012 Natural product pharmacophore
585 Afatinib Gilotrif Anticancer 2013 Natural product pharmacophore
586 Canagliflozin Invokana Antidiabetic 2013 Natural product pharmacophore
587 Dabrafenib mesilate Tafinlar Anticancer 2013 Natural product pharmacophore
588 FF/GW-642444 Breo COPD 2013 Natural product pharmacophore
589 Ibrutinib Imbruvica Anticancer 2013 Natural product pharmacophore
590 Olodaterol hydrochloride Striverdi COPD 2013 Natural product pharmacophore
591 Ponatinib Iclusig Anticancer 2013 Natural product pharmacophore
592 Simeprevir Sovriad Antiviral 2013 Natural product pharmacophore
593 Trametinib DMSO Mekinist Anticancer 2013 Natural product pharmacophore
594 Belinostat Beleodaq Anticancer 2014 Natural product pharmacophore
595 Eliglustat tartrate Cerdelga Gaucher’s disease 2014 Natural product pharmacophore
596 Empagliflozin Jardiance Antidiabetic 2014 Natural product pharmacophore
597 Idelalisib Zydelig Anticancer 2014 Natural product pharmacophore
598 Ipragliflozin proline Suglat Antidiabetic 2014 Natural product pharmacophore
599 Luseogliflozin Lusefi Antidiabetic 2014 Natural product pharmacophore
600 Ombitasvir Viekira Pak Antiviral 2014 Natural product pharmacophore
601 Paritaprevir Viekira Pak Antiviral 2014 Natural product pharmacophore
602 Tofogliflozin Apleway Antidiabetic 2014 Natural product pharmacophore
603 Vaniprevir Vanihep Antiviral 2014 Natural product pharmacophore
Ayurvedic Knowledge Inspired Approach to Modern Drug Discovery 353
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Table 13.2 (Continued)
No. Generic name Trade name Disease Year Source
604 Eluxadoline Viberzi Irritable bowel syndrome 2015 Natural product pharmacophore
605 Lenvatinib mesylate Lenvima Anticancer 2015 Natural product pharmacophore
606 Osimertinib mesylate Tagrisso Anticancer 2015 Natural product pharmacophore
607 Palbociclib Ibrance Anticancer 2015 Natural product pharmacophore
608 Safinamide mesilate Xadago Antiepileptic 2015 Natural product pharmacophore
609 Selexipag Uptravi PAH 2015 Natural product pharmacophore
610 Narlaprevir arlansa Antiviral 2016 Natural product pharmacophore
611 Olmutinib Olita Anticancer 2016 Natural product pharmacophore
612 Opicapone Ongentys Parkinson’s disease 2016 Natural product pharmacophore
613 Abemaciclib mesylate Verzenio Anticancer 2017 Natural product pharmacophore
614 Acalabrutinib Calquence Anticancer 2017 Natural product pharmacophore
615 Baricitinib Olumiant Antiarthritic 2017 Natural product pharmacophore
616 Brigatinib Alunbrig Anticancer 2017 Natural product pharmacophore
617 Copanlisib Aliqopa Anticancer 2017 Natural product pharmacophore
618 Deutetrabenazine Austedo Tardive dyskinesia 2017 Natural product pharmacophore
619 Ertugliflozin Steglatro Antidiabetic 2017 Natural product pharmacophore
620 Glecaprevir/pibrentasvir Maviret Antiviral 2017 Natural product pharmacophore
621 Macimoralin acetate Macrilen GH deficit 2017 Natural product pharmacophore
622 Neratinib Nerlynx Anticancer 2017 Natural product pharmacophore
623 Pitavastatin magnesium Zypitamag Hypocholesterolemic 2017 Natural product pharmacophore
624 Ribociclib Kisqali Anticancer 2017 Natural product pharmacophore
625 Telotristat etiprate Xermelo Ulcerative colitis 2017 Natural product pharmacophore
626 Tivozanib Fotivda Anticancer 2017 Natural product pharmacophore
627 Valbenazine Ingrezza Tardive dyskinesia 2017 Natural product pharmacophore
628 Albuvirtide Aikening Antiviral 2018 Natural product pharmacophore
629 Dacomitinib Vizimpro Anticancer 2018 Natural product pharmacophore
630 Danoprevir Ganovo Antiviral 2018 Natural product pharmacophore
631 Duvelisib Copiktra Anticancer 2018 Natural product pharmacophore
632 Fostamatinib disodium Tavalisse Idiopathic thrombocytopenia 2018 Natural product pharmacophore
633 Fruquintinib Elunate Anticancer 2018 Natural product pharmacophore
634 Gilteritinib Xospata Anticancer 2018 Natural product pharmacophore
354 Chapter 13
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635 Ivosidenib Tibsovo Anticancer 2018 Natural product pharmacophore
636 Larotrectinib sulfate Vitrakvi Anticancer 2018 Natural product pharmacophore
637 Pyrotinib Airuini Anticancer 2018 Natural product pharmacophore
638 Revefenacin Yupelri COPD 2018 Natural product pharmacophore
639 Vibegron Beova Overactive bladder 2018 Natural product pharmacophore
640 Bremelanotide Vyleesi Female sexual dysfunction 2019 Natural product pharmacophore
641 Entrectinib Rozlytrek Anticancer 2019 Natural product pharmacophore
642 Erdafitinib Balversa Anticancer 2019 Natural product pharmacophore
643 Fedratinib HCl Inrebic Anticancer 2019 Natural product pharmacophore
644 Peficitinib hydrobromide Smyraf Antiarthritic 2019 Natural product pharmacophore
645 Remogliflozin etaborate Remo Antidiabetic 2019 Natural product pharmacophore
646 Solriamfetol hydrochloride Sunosi Antinarcolepsy 2019 Natural product pharmacophore
647 Sotagliflozin Zynquista Antidiabetic 2019 Natural product pharmacophore
648 Upadacitinib tartrate Rinvoq Antiarthritic 2019 Natural product pharmacophore
649 Selegiline HCl Jumex Parkinson’s disease 1981 Natural product mimic
650 Amrinone Inocor Cardiotonic 1983 Natural product mimic
651 Fluvoxamine maleate Floxyfral Antidepressant 1983 Natural product mimic
652 Tizanidine Sirdalud Muscle relaxant 1984 Natural product mimic
653 Toloxatone Humoryl Antidepressant 1984 Natural product mimic
654 Bunazosin HCl Detandol Antihypertensive 1985 Natural product mimic
655 Camostat mesylate Foipan Anticancer 1985 Natural product mimic
656 Ketanserin Serefrex Antihypertensive 1985 Natural product mimic
657 Trimazosin HCl Supres Antihypertensive 1985 Natural product mimic
658 Amisulpride Socian Antipsychotic 1986 Natural product mimic
659 Fluoxetine HCI Prozac Antidepressant 1986 Natural product mimic
660 Nafamostat mesylate Futhan Pancreatitis 1986 Natural product mimic
661 Dapiprazole HCl Glamidolo Antiglaucoma 1987 Natural product mimic
662 Flumazenil Anexate Benzodiazepine antagonist 1987 Natural product mimic
663 Levosulpiride Levopraid Antipsychotic 1987 Natural product mimic
664 Picotamide Plactidil Antithrombotic 1987 Natural product mimic
665 Alpiropride Rivestel Antimigraine 1988 Natural product mimic
666 Apraclonidine HCl Lopidine Antiglaucoma 1988 Natural product mimic
667 Cilostazol Retal Antithrombotic 1988 Natural product mimic
668 Doxazosin mesylate Carduran Antihypertensive 1988 Natural product mimic
Ayurvedic Knowledge Inspired Approach to Modern Drug Discovery 355
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Table 13.2 (Continued)
No. Generic name Trade name Disease Year Source
669 Enoximone Perfan Cardiotonic 1988 Natural product mimic
670 Ozagrel sodium Xanbon Antithrombotic 1988 Natural product mimic
671 Ibudilast Ketas Antiasthmatic 1989 Natural product mimic
672 Milrinone Corotrope Cardiotonic 1989 Natural product mimic
673 Setiptiline Tecipul Antidepressant 1989 Natural product mimic
674 Tolrestat Alredase Antidiabetic 1989 Natural product mimic
675 Toremifene Fareston Anticancer 1989 Natural product mimic
676 Cinitapride Cidine Gastroprokinetic 1990 Natural product mimic
677 Moclobemide Aurorix Antidepressant 1990 Natural product mimic
678 Setraline hydrochloride Lustral Antidepressant 1990 Natural product mimic
679 Alpidem Ananxyl Anxiolytic 1991 Natural product mimic
680 Centchroman Choice 7 Contraception 1991 Natural product mimic
681 Clospipramine hydrochloride Cremin Neuroleptic 1991 Natural product mimic
682 Dezocine Dalgan Analgesic 1991 Natural product mimic
683 Nemonapride Emilace Neuroleptic 1991 Natural product mimic
684 Paroxetine Seroxat Antidepressant 1991 Natural product mimic
685 Terbinafine hydrochloride Lamisil Antifungal 1991 Natural product mimic
686 Butenafine hydrochloride Mentax Antifungal 1992 Natural product mimic
687 Epalrestat Kinedak Antidiabetic 1992 Natural product mimic
688 Risperidone Risperdal Neuroleptic 1993 Natural product mimic
689 Sarpogrelate HCI Anplag Platelet aggreg. inhib. 1993 Natural product mimic
690 Tacrine HCI Cognex Alzheimer’s disease 1993 Natural product mimic
691 Tamsulosin HCI Harnal Benign prostatic hypertrophy 1993 Natural product mimic
692 Broxaterol Summair Antiasthmatic 1994 Natural product mimic
693 Losartan potassium Cozaar Antihypertensive 1994 Natural product mimic
694 Mirtazapine Remeron Antidepressant 1994 Natural product mimic
695 Nefazodone hydrochloride Serzone Antidepressant 1994 Natural product mimic
696 Venlafaxine Effexor Antidepressant 1994 Natural product mimic
697 Anastrozole Arimidex Anticancer 1995 Natural product mimic
698 Bicalutamide Casodex Anticancer 1995 Natural product mimic
699 Dorzolamide HCl Trusopt Antiglaucoma 1995 Natural product mimic
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700 Fadrozole HCl Afema Anticancer 1995 Natural product mimic
701 Seratrodast Bronica Antiasthmatic 1995 Natural product mimic
702 Brimonidine Alphagan Antiglaucoma 1996 Natural product mimic
703 Letrazole Femara Anticancer 1996 Natural product mimic
704 Meloxicam Mobec Antiarthritic 1996 Natural product mimic
705 Olanzapine Zyprexa Neuroleptic 1996 Natural product mimic
706 Talipexole Domin Parkinson’s disease 1996 Natural product mimic
707 Tandospirone Sediel Anxiolytic 1996 Natural product mimic
708 Valsartan Diovan Antihypertensive 1996 Natural product mimic
709 Zafirlukast Accolate Antiasthmatic 1996 Natural product mimic
710 Budipine Parkinsan Parkinson’s disease 1997 Natural product mimic
711 Candesartan cilexetil Atacand Antihypertensive 1997 Natural product mimic
712 Dexfenfluramine Redux Antiobesity 1997 Natural product mimic
713 Donepezil HCl Aricept Alzheimer’s disease 1997 Natural product mimic
714 Eprosartan Teveten Antihypertensive 1997 Natural product mimic
715 Irbesartan Avapro Antihypertensive 1997 Natural product mimic
716 Milnacipran Ixel Antidepressant 1997 Natural product mimic
717 Nebivolol Nebilet Antihypertensive 1997 Natural product mimic
718 Pramipexole HCl Mirapex Parkinson’s disease 1997 Natural product mimic
719 Quetiapine fumarate Seroquel Neuroleptic 1997 Natural product mimic
720 Reboxetine Edronax Antidepressant 1997 Natural product mimic
721 Rivastigmin Exelon Alzheimer’s disease 1997 Natural product mimic
722 Tolterodine Detrusitol Urinary incontinence 1997 Natural product mimic
723 Troglitazone Rezulin Antidiabetic 1997 Natural product mimic
724 Zileuton Zyflo Antiasthmatic 1997 Natural product mimic
725 Brinzolamide Azopt Antiglaucoma 1998 Natural product mimic
726 Clopidogrel hydrogensulfate Plavix Antithrombotic 1998 Natural product mimic
727 Fenoldopam mesylate Corlopam Antihypertensive 1998 Natural product mimic
728 Fomepizole Antizol Antidote 1998 Natural product mimic
729 Leflunomide Arava Antiarthritic 1998 Natural product mimic
730 Montelukast sodium Singulair Antiasthmatic 1998 Natural product mimic
731 Mosapride citrate Gasmotin Gastroprokinetic 1998 Natural product mimic
732 Raloxifene HCl Evista Calcium metabolism 1998 Natural product mimic
733 Sibutramine Meridia Antiobesity 1998 Natural product mimic
734 Tirofiban HCl Aggrastat Antithrombotic 1998 Natural product mimic
Ayurvedic Knowledge Inspired Approach to Modern Drug Discovery 357
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Table 13.2 (Continued)
No. Generic name Trade name Disease Year Source
735 Celecoxib Celebrex Antiarthritic 1999 Natural product mimic
736 Naftopidil Flivas Dysuria 1999 Natural product mimic
737 Rofecoxib Vioxx Antiarthritic 1999 Natural product mimic
738 Rosiglitazone maleate Avandia Antidiabetic 1999 Natural product mimic
739 Telmisartan Micardis Antihypertensive 1999 Natural product mimic
740 Dexmedetomidine HCl Precedex Sedative 2000 Natural product mimic
741 Levosimendan Simdax MI, acute 2000 Natural product mimic
742 Liranaftate Zefnart Antifungal 2000 Natural product mimic
743 Bosentan Tra-cleer Antihypertensive 2001 Natural product mimic
744 Imatinib mesilate Gleevec Anticancer 2001 Natural product mimic
745 Aripiprazole Abilify Neuroleptic 2002 Natural product mimic
746 Etoricoxib Arcoxia Antiarthritic 2002 Natural product mimic
747 Gefitinib Iressa Anticancer 2002 Natural product mimic
748 Olmesartan medoxil Benicar Antihypertensive 2002 Natural product mimic
749 Parecoxib sodium Dynastat Analgesic 2002 Natural product mimic
750 Sivelestat sodium hydrate Elaspol Respiratory distress syndrome 2002 Natural product mimic
751 Temoporfin Foscan Anticancer 2002 Natural product mimic
752 Valdecoxib Bextra Antiarthritic 2002 Natural product mimic
753 Aprepitant Emend Antiemetic 2003 Natural product mimic
754 Bortezomib Velcade Anticancer 2003 Natural product mimic
755 Duloxetine hydrochloride Cymbalta Antidepressant 2004 Natural product mimic
756 Erlotinib hydrochloride Tarceva Anticancer 2004 Natural product mimic
757 Darifenacin hydrobromide Emselex Urinary incontinence 2005 Natural product mimic
758 Lumiracoxib Prexige Osteoarthritis 2005 Natural product mimic
759 Ramelteon Rozerem Insomnia 2005 Natural product mimic
760 Conivaptan HCl Vaprisol Diuretic 2006 Natural product mimic
761 Darunavir Prezista Antiviral 2006 Natural product mimic
762 Dasatinib Sprycel Anticancer 2006 Natural product mimic
763 Mozavaptan Physuline Diuretic 2006 Natural product mimic
764 Rimonabant Acomplia Antiobesity 2006 Natural product mimic
765 Rotigotine Neupro Parkinson’s disease 2006 Natural product mimic
358 Chapter 13
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766 Sitagliptin Januvia Antidiabetic 2006 Natural product mimic
767 Sitaxsentan sodium Thelin PAH 2006 Natural product mimic
768 Sunitinib malate Sutent Anticancer 2006 Natural product mimic
769 Varenicline tartrate Chantix Smoking cessation 2006 Natural product mimic
770 Ambrisentan Letairis PAH 2007 Natural product mimic
771 Lapatinib ditosylate Tykerb Anticancer 2007 Natural product mimic
772 Nilotinib hydrochloride Tasigna Anticancer 2007 Natural product mimic
773 Paliperidone Invega Schizophrenia 2007 Natural product mimic
774 Vildagliptin Galvus Antidiabetic 2007 Natural product mimic
775 Blonanserin Lonasen Antipsychotic 2008 Natural product mimic
776 Desvenlafaxine succinate Pristiq Antidepressant 2008 Natural product mimic
777 Fesoterodine fumarate Toviaz Urinary incontinence 2008 Natural product mimic
778 Fosaprepitant dimeglumine Ivemend Antiemetic 2008 Natural product mimic
779 Asenapine maleate Saphris Antipsychotic 2009 Natural product mimic
780 Dapoxetine HCl Priligy Premature ejaculation 2009 Natural product mimic
781 Febuxostat Adenuric Hyperuricemia 2009 Natural product mimic
782 Lasofoxifene tartrate Fablyn Calcium metabolism 2009 Natural product mimic
783 Niacin/laropiprant Tredaptive Hypocholesterolemic 2009 Natural product mimic
784 Pazopanib Votrient Anticancer 2009 Natural product mimic
785 Prasugrel Efient Antithrombotic 2009 Natural product mimic
786 Saxagliptin Onglyza Antidiabetic 2009 Natural product mimic
787 Tapentadol HCL Nucynta Analgesic 2009 Natural product mimic
788 Tolvaptan Samsca Hyponatremia 2009 Natural product mimic
789 Alogliptin benzoate Nesina Antidiabetic 2010 Natural product mimic
790 Bazedoxifene acetate Conbriza Calcium metabolism 2010 Natural product mimic
791 Iloperidone Fanapt Antipsychotic 2010 Natural product mimic
792 Peramivir PeramiFlu Antiviral 2010 Natural product mimic
793 Prucalopride Resolor Constipation 2010 Natural product mimic
794 Roflumilast Daxas COPD 2010 Natural product mimic
795 Linagliptin Tradjenta Antidiabetic 2011 Natural product mimic
796 Lurasidone hydrochloride Latuda Antipsychotic 2011 Natural product mimic
797 Vilazodone hydrochloride Vibryd Antidepressant 2011 Natural product mimic
798 Aclidinium bromide Tudorza COPD 2012 Natural product mimic
799 Anagliptin Suiny Antidiabetic 2012 Natural product mimic
800 Azilsartan medoxomil Azilva Antihypertensive 2012 Natural product mimic
Ayurvedic Knowledge Inspired Approach to Modern Drug Discovery 359
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Table 13.2 (Continued)
No. Generic name Trade name Disease Year Source
801 Enzalutamide Xtandi Anticancer 2012 Natural product mimic
802 Gemiglptin Zemiglo Antidiabetic 2012 Natural product mimic
803 Lorcaserin hydrochloride Belviq Anti-obesity 2012 Natural product mimic
804 Teneligliptin hydrobromide Tenelia Antidiabetic 2012 Natural product mimic
805 Cobicistat Tybost Antiviral 2013 Natural product mimic
806 Levomilnacipran Fetzima Antidepressant 2013 Natural product mimic
807 Macitentan Opsumit PAH 2013 Natural product mimic
808 Ospemifene Osphena Dyspareunia 2013 Natural product mimic
809 Topiroxostat Topiloric Gout 2013 Natural product mimic
810 Vortioxetine Brintellix Antidepressant 2013 Natural product mimic
811 Alectinib hydrochloride Alecensa Anticancer 2014 Natural product mimic
812 Apatinib mesylate Anticancer 2014 Natural product mimic
813 Apremilast Otezla Antipsoriatic 2014 Natural product mimic
814 Asunaprevir Sunvepra Antiviral 2014 Natural product mimic
815 Ceritinib Zykadia Anticancer 2014 Natural product mimic
816 Ledipasvir Harvoni Antiviral 2014 Natural product mimic
817 Netupitent Akynzeo Antinauseant 2014 Natural product mimic
818 Nintedanib Ofev Idiopathic pulmonary fibrosis 2014 Natural product mimic
819 Suvorexant Belsomra Insomnia 2014 Natural product mimic
820 Tasimelteon Hetlioz Free-running circadian disorder 2014 Natural product mimic
821 Umeclidinium bromide Incruse COPD 2014 Natural product mimic
822 Aripiprazole laurate Aristada Schizophrenia 2015 Natural product mimic
823 Brexpiprazole Rexulti Schizophrenia 2015 Natural product mimic
824 Cariprazine hydrochloride Vraylar Schizophrenia 2015 Natural product mimic
825 Chidamide Epidaza Anticancer 2015 Natural product mimic
826 Evogliptin hydrochloride Suganon Antidiabetic 2015 Natural product mimic
827 Flibanserin Addyi Female sexual dysfunction 2015 Natural product mimic
828 Ixazomib citrate Ninlaro Anticancer 2015 Natural product mimic
829 Lusutrombopag Mulpleta Idiopathic thrombocytopenia 2015 Natural product mimic
830 Omarigliptin Marizev Antidiabetic 2015 Natural product mimic
831 Panobinostat lactate Farydak Anticancer 2015 Natural product mimic
832 Polmacoxib Acelex Antiinflammatory 2015 Natural product mimic
360 Chapter 13
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833 Rolapitant hydrochloride Varubi Antinauseant 2015 Natural product mimic
834 Trelagliptin succinate Zafatek Antidiabetic 2015 Natural product mimic
835 Crisaborole Eucrisa Antipsoriatic 2016 Natural product mimic
836 Elbasvir Erelsa Antiviral 2016 Natural product mimic
837 Gosogliptin hydrochloride SatRx Antidiabetic 2016 Natural product mimic
838 Grazoprevir Grazyna Antiviral 2016 Natural product mimic
839 Lifitegrast Xiidra Dry eye syndrome 2016 Natural product mimic
840 Pimavanserin tartrate Nuplazid Parkinson’s disease 2016 Natural product mimic
841 Pitolisant hydrochloride Wakix Antinarcolepsy 2016 Natural product mimic
842 Betrixaban Bevyxxa Anticoagulant 2017 Natural product mimic
843 Enasidenib mesylate Idhifa Anticancer 2017 Natural product mimic
844 Niraparib Zejula Anticancer 2017 Natural product mimic
845 Solifenacin tartrate Vesigeum Urinary incontinence 2017 Natural product mimic
846 Apalutamide Erleada Anticancer 2018 Natural product mimic
847 Avatrombopag maleate Doptelet Idiopathic thrombocytopenia 2018 Natural product mimic
848 Baloxavir marboxil Xofluza Antiviral 2018 Natural product mimic
849 Binimetinib Mektovi Anticancer 2018 Natural product mimic
850 Binimetinib Mektovi Anticancer 2018 Natural product mimic
851 Elagolix sodium Orilissa Endometriosis 2018 Natural product mimic
852 Elobixibat Goofice Chronic idiopathic constipation 2018 Natural product mimic
853 Encorafenib Braftovi Anticancer 2018 Natural product mimic
854 Glasdegib maleate Daurismo Anticancer 2018 Natural product mimic
855 Glycopyrrolate tosylate Qbrexza Hyperhydrosis 2018 Natural product mimic
856 Ivosidenib Tibsovo Anticancer 2018 Natural product mimic
857 Lorlatinib Lorbrena Anticancer 2018 Natural product mimic
858 Omidenepag isopropyl Eybelis Antiglaucoma 2018 Natural product mimic
859 Tecovirimat Arestvyr Antiviral 2018 Natural product mimic
860 Alpelisib Piqray Anticancer 2019 Natural product mimic
861 Darolutamide Nubeqa Anticancer 2019 Natural product mimic
862 Esaxerenone Minnebro Antihypertensive 2019 Natural product mimic
863 Pexidartinib Turalio Anticancer 2019 Natural product mimic
864 Qizartinib Vanflyta Anticancer 2019 Natural product mimic
865 Relugolix Relumina Uterine fibroids 2019 Natural product mimic
Ayurvedic Knowledge Inspired Approach to Modern Drug Discovery 361
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