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XII
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List of Contributors
Philippe Cluzel
Radiology Department
Groupe Hospitalier Piti-Salptrire
47±83 bd de l'HÖpital
75013 Paris
France
Alain Cerene
Department of Cardiovascular Surgery
Rangueil University Hospital
1 av J. Poulhes ± TSA 50032
31059 Toulouse CEDEX 9
France
C. Cron
Department of Cardio Vascular Surgery
University Hospital Rangueil
01 av J Poulhes
31403 Toulouse
France
Michael D. Dake
University of Virginia Health System
Charlottesville, VA 22908-0170
USA
Camille Dambrin
Department of Cardiovascular Surgery
Rangueil University Hospital
1 av J. Poulhes ± TSA 50032
31059 Toulouse CEDEX 9
France
Bertrand De Latour
Cardiovascular and Thoracic Surgery Department
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Gabriel Delorme
Cardiology Department
HÖpital Ambroise Par
9 av Charles de Gaulle
92100 Boulogne Billancourt
France
Karl Dossche
St. Antonius Hospital
Department of Cardiothoracic Surgery
Koekoekslaan 1
3435 CM Nieuwegein
The Netherlands
Chris Elkins
Departments of Mechanical Engineering and Radiology
Stanford University
Stanford, CA 94305
USA
Anthony L. Estrera
Department of Cardiothoracic and Vascular Surgery
The University of Texas at Houston Medical School
6410 Fannin, Suite 450, CV Surgery
Houston, TX 77030
USA
Artur Evangelista
Department of Cardiac Imaging
Cardiology Department
Hospital Universitari Vall d'Hebron
Barcelona
Spain
Rosella Fattori
Cardiovascular Unit
Department of Radiology
S. Orsola University Hospital
Bologna
Italy
Jeffrey A. Feinstein
Pediatrics
Division of Pediatric Cardiology
Associate Director
Pediatric and Congenital Cardiac Catheterization
Lucile Packard Children's Hospital
Stanford University Medical Center
750 Welch Road, Suite 305
Palo Alto, CA 94304
USA
Gerard Fournial
Department of Cardiovascular Surgery
CHU Rangueil
Toulouse
France
JoaquÌn FerreirÕs
Departamento de RadiologÌa
Hospital Universitario de San Carlos
Madrid
Spain
Virginia Gaxotte
Service de Radiologie et d'Imagerie Cardio-vasculaire
HÖpital Cardiologique ± CHRU de Lille
Bd du Professeur Leclerc
59037 Lille CEDEX
France

List of Contributors
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XIII
Betti Giusti
Department of Medical and Surgical Critical Care
Thrombosis Centre
and Centre for the Study at Molecular
and Clinical Level of Chronic,
Degenerative and Neoplastic Diseases
to Develop Novel Therapies (DENOTHE)
University of Florence
Viale Morgagni 85
50134 Florence
Italy
Teresa Gonzlez-Alujas
Echocardiography
Cardiology Department
Hospital Universitari Vall d'Hebron
Barcelona
Spain
Randall Griepp
Department of Cardiothoracic Surgery
Mount Sinai Medical Center
1190 Fifth Avenue, Box 1028
New York, NY 10029
USA
Jean Philippe Guibaud
Department of Cardiovascular
and Paediatric Cardiac Surgery
Bordeaux Heart University Hospital
Avenue de Magellan
33604 Pessac
France
Jean-Franois Heautot
Radiology and Medical Imaging Department
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Tadanori Hirano
Department of Radiology
Matsusaka Central General Hospital
102 Kawai, Matsusaka
Mie 515-8566
Japan
Hiroaki Hosokawa
Department of Clinical Research
National Hospital Organization
Toyohashi Hospital
Aichi
Japan
Tam T.T. Huynh
Department of Cardiothoracic and Vascular Surgery
The University of Texas at Houston Medical School
6410 Fannin, Suite 450, CV Surgery
Houston, TX 77030
USA
Kanji Inoue
PTMC Institute
39-1 Sakurai-Cho, Kamigamo
Kita-Ku, Kyoto 603-8054
Japan and
Clinical Department of Cardiovascular Surgery
Faculty of Medicine
Kyoto University
Shimabara Hospital
7-4 Kosaka-Cho, Shimokyo-Ku
Kyoto, 600-8821
Japan
Krassi Ivancev
Endovascular Center
Malmæ University Hospital
20502 Malmæ
Sweden
Michael J. Jacobs
Department of Surgery
University Hospital Maastricht
P.O. Box 5800
6202 AZ Maastricht
The Netherlands
Patrick Jgo
Internal Medicine Unit
HÖpital Sud
16 boulevard de Bulgarie
35203 Rennes
France
Francis Joffre
Department of Radiology
Rangueil University Hospital
1 av J. Poulhes ± TSA 50032
31059 Toulouse CEDEX 9
France
Guillaume Jondeau
Consultation Multidisciplinaire Marfan
HÖpital Ambroise Par
9 Av Charles de Gaulle
92100 Boulogne Billancourt
France

XIV
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List of Contributors
Cyryl Kakon
Cardiovascular and Thoracic Surgery Department
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Matthias Karck
Division of Thoracic and Cardiovascular Surgery
Hannover Medical School
Carl-Neuberg-Str. 1
30625 Hannover
Germany
Noriyuki Kato
Department of Radiology
Mie University Hospital
2-174 Edobashi, Tsu
Mie 514-8507
Japan
Nawid Khaladj
Division of Thoracic and Cardiovascular Surgery
Hannover Medical School
Carl-Neuberg-Str. 1
30625 Hannover
Germany
Takeshi Kimura
Department of Cardiovascular Medicine
Graduate School of Medicine
Kyoto University
and Director
Division of Clinical Cardiology
Kyoto University Hospital
Kyoto
Japan
Francois G. Lacour-Gayet
Pediatric Cardiac Surgery
The Children's Hospital Heart Institute
1056 East 19th Avenue, B200
Denver, CO 80218-1088
USA
John F. LaDisa Jr.
Pediatrics
Division of Cardiology
Stanford University Medical Center
750 Welch Road, Suite 305
Palo Alto, CA 94304
USA
Thierry Langanay
Cardiovascular and Thoracic Surgery Department
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Do Yun Lee
Department of Diagnostic Radiology
Yonsei University College of Medicine
134 Shinchon-dong
Seodaemun-gu
Seoul 120-752
Korea
Alain Leguerrier
Cardiovascular and Thoracic Surgery Department
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Bansi Koul
Department of Cardiothoracic Surgery
University Hospital of Lund
22185 Lund
Sweden
Louis Labrousse
Department of Cardiac and Vascular Surgery
HÖpital Haut-Lvque
Bordeaux University Hospital
33604 Pessac CEDEX
France
B. Leobon
Department of Cardio Vascular Surgery
University Hospital Rangueil
01 av J Poulhes
31403 Toulouse
France
Pascal Leprince
CT Surgery Department
Groupe Hospitalier Piti-Salptrire
47±83 bd de l'HÖpital
75013 Paris
France

List of Contributors
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XV
Christophe Lions
Service de Radiologie et d'Imagerie Cardio-vasculaire
HÖpital Cardiologique ± CHRU de Lille
Bd du Professeur Leclerc
59037 Lille CEDEX
France
Bertrand Marcheix
Department of Cardiovascular Surgery
Rangueil University Hospital
1 av J. Poulhes ± TSA 50032
31059 Toulouse CEDEX 9
France
Pierre Massabuau
Department of Cardiology
Rangueil University Hospital
1 av J. Poulhes ± TSA 50032
31059 Toulouse CEDEX 9
France
Genevive Meites
Dpartement d'Anesthsie Ranimation
Centre Hospitalier Universitaire
31059 Toulouse
France
Charles C. Miller III
Center for Clinical Research
and Evidence-Based Medicine
Center for Biotechnology
Department of Cardiothoracic and Vascular Surgery
The University of Texas at Houston Medical School
6410 Fannin, Suite 450, CV Surgery
Houston, TX 77030
USA
Olivier Milleron
Cardiology Department
HÖpital Ambroise Par
9 av Charles de Gaulle
92100 Boulogne Billancourt
France
R. Scott Mitchell
Department of Cardiothoracic Surgery
Stanford University School of Medicine
300 Pasteur Drive
Stanford, CA 94305
USA
Ziad Negaiwi
Service de Radiologie et d'Imagerie Cardio-vasculaire
HÖpital Cardiologique ± CHRU de Lille
Bd du Professeur Leclerc
59037 Lille CEDEX
France
Christoph A. Nienaber
Division of Cardiology
University Hospital Rostock
Rostock School of Medicine
Ernst-Heydemann-Str. 6
18057 Rostock
Germany
Philippe Otal
Department of Radiology
Rangueil University Hospital
1 av J. Poulhes ± TSA 50032
31059 Toulouse CEDEX 9
France
Davide Pacini
Department of Cardiac Surgery
S. Orsola University Hospital
Bologna
Italy
Alain Pavie
CT Surgery Department
Groupe Hospitalier Piti-Salptrire
47±83 bd de l'HÖpital
75013 Paris
France
Oliver Pellerin
Department of Cardiovascular
and Interventional Radiology
HÖpital Europen Georges Pompidou
75015 Paris
France
Guglielmina Pepe
Department of Medical
and Surgical Critical Care
Thrombosis Centre
and Centre for the Study at Molecular
and Clinical Level of Chronic,
Degenerative and Neoplastic Diseases
to Develop Novel Therapies (DENOTHE)
University of Florence
Viale Morgagni 85
50134 Florence
Italy
Bora Peynircioglu
Section of Vascular/Interventional Radiology
Department of Radiology
School of Medicine
Hacettepe University
Ankara
Turk ey

XVI
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List of Contributors
Eyal E. Porat
Department of Cardiothoracic and Vascular Surgery
The University of Texas at Houston Medical School
6410 Fannin, Suite 450, CV Surgery
Houston, TX 77030
USA
Maria Cristina Porciani
Department of Medical and Surgical Critical Care
University of Florence
Viale Morgagni 85
50134 Florence
Italy
Alain Prat
Cardiac and Vascular Surgery Unit
HÖpital Cardiologique ± CHRU de Lille
Bd du Professeur Leclerc
59037 Lille CEDEX
France
Matthieu Revest
Internal Medicine Unit
HÖpital Sud
16 Boulevard de Bulgarie
35203 Rennes
France
Xavier Roques
Department of Cardiovascular
and Paediatric Cardiac Surgery
Bordeaux Heart University Hospital
Avenue de Magellan
33604 Pessac
France
Herv Rousseau
Department of Radiology
Rangueil University Hospital
1 av J. Poulhes ± TSA 50032
31059 Toulouse CEDEX 9
France
Hazim J. Safi
Department of Cardiothoracic and Vascular Surgery
The University of Texas at Houston Medical School
6410 Fannin, Suite 450, CV Surgery
Houston, TX 77030
USA
Jos Alberto San Romn
ICICOR ± Instituto de las Ciencias del CorazÕn
Hospital Universitario de Valladolid
Valladolid
Spain
Marc Sapoval
Facult de Mdecine Ren Descartes Paris 5
Department of Cardiovascular
and Interventional Radiology
HÖpital Europen Georges Pompidou
75015 Paris
France
Hans-Joachim Schåfers
Department of Thoracic and Cardiovascular Surgery
Universitåtsklinikum des Saarlandes
Kirrbergerstr. 1
66424 Homburg/Saar
Germany
Marc Schepens
St. Antonius Hospital
Department of Cardiothoracic Surgery
Koekoekslaan 1
3435 CM Nieuwegein
The Netherlands
Michel Sellin
Service d'Anesthsie Ranimation 2
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Takatsugu Shimono
Department of Thoracic and Cardiovascular Surgery
Mie University Hospital
2-174 Edobashi, Tsu
Mie 514-8507
Japan
David Spielvogel
New York Medical College
Valhalla, NY 10595
USA
Charles A. Taylor
Mechanical Engineering
Bioengineering, Surgery, Pediatrics (by courtesy)
& Radiology (by courtesy)
Stanford University Medical Center
750 Welch Road, Suite 305
Palo Alto, CA 94304
USA
Frdric Thony
Service Central de Radiologie et Imagerie Mdicale
CHU ± Scrim
BP 217, 38043 Grenoble 9
France

List of Contributors
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XVII
Vincent Tran Dinh
Radiology and Medical Imaging Department
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Jos C. van den Berg
Service of Interventional Radiology
Ospedale Regionale di Lugano
sede Civico
Via Tesserete 46
6900 Lugano
Switzerland
Pieter J. A. van der Starre
Department of Anesthesia
Stanford University School of Medicine
300 Pasteur Drive
Stanford, CA 94305
USA
Jean-Philippe Verhoye
Cardiovascular and Thoracic Surgery Department
University Hospital Center of Rennes
Pontchaillou Hospital
Rue Henri Le Guillou
35033 Rennes CEDEX 9
France
Isidre Vilacosta
Cardiology
Instituto Cardiovascular
Hospital Universitario de San Carlos
Madrid
Spain
David M. Williams
Vascular and Interventional Radiology
University of Michigan Hospitals
Ann Arbor, MI 48109-0030
USA
Jessica Wilson
Cardiology Department
HÖpital Ambroise Par
9 av Charles de Gaulle
92100 Boulogne Billancourt
France
Serge Willoteaux
Service de Radiologie et d'Imagerie Cardio-vasculaire
HÖpital Cardiologique ± CHRU de Lille
Bd du Professeur Leclerc
59037 Lille CEDEX
France
Jong Yun Won
Department of Diagnostic Radiology
Yonsei University College of Medicine
134 Shinchon-dong, Seodaemun-gu
Seoul 120-752
Korea
Sir Magdi Yacoub
Cardiothoracic Surgery
Imperial College London
Heart Science Centre
Harefield
Middlesex, UB9 6JH
UK
David S. Wang
Howard Hughes Medical Institute Fellow
Section of Cardiovascular and Interventional Radiology
Stanford University School of Medicine
300 Pasteur Drive
Stanford, CA 94305
USA

Radio-Anatomy
https://t.me/med1917
of the Thoracic Aorta.
3D Imaging of the Aorta (CT, MRI
and 3D Rotational Angiography)
Jos C. van den Berg
Chapter
1
Contents
1.1 Introduction .......................
1.2 Imaging Modalities ................... 3
1.2.1 Multidetector Row CTA ............. 3
1.2.2 MR Angiography ................. 4
1.2.3 3D Rotational Angiography ........... 5
1.3 GrossAnatomy ...................... 5
1.3.1 Coronary arteries ................ 6
1.3.2 Supra-aortic Vessels ............... 7
1.3.3 Intercostal Arteries ............... 8
1.3.4 Anterior Spinal Artery ............. 8
1.3.5 Bronchial Arteries ................ 8
1.4 Congenital Variants and Abnormalities ........ 10
1.4.1 Coronary Arteries ................ 10
1.4.2 Supra-aortic Vessels and Aortic Arch ..... 10
1.4.3 aortic Coarctation ................ 13
1.5 Acquired Aortic Disease ................. 15
1.5.1 Dissection ..................... 15
1.5.2 Aneurysms .................... 15
1.6 Conclusions ........................ 17
1.1 Introduction
Traditionally radiological imaging of the human body
has been limited to a two-dimensional depiction of a
three-dimensional reality. The thoracic aorta modalities
most commonly used were plain (chest) radiography,
(digital subtraction) angiography and single-slice computerized tomography (CT). Over the last decade tremendous technical advancements have been made in
various imaging modalities. The speed of data acquisition with CT scanning and MRI has increased, thus enabling fast, high-resolution axial imaging. The concurrent development of advanced 3D volume-rendering
techniques, which require high computational speed, allowed for the development of CT angiography (CTA),
magnetic resonance angiography (MRA) and 3D rotational angiography (3D-RA). In this chapter a brief
overview on the technical aspects of the currently available modalities will be given and advantages and disad-
3
vantages of each technique will be discussed. The radiological anatomy of the thoracic aorta and its branches
as depicted with these new imaging techniques will be
described in detail.
1.2 Imaging Modalities
For successful evaluation of vascular pathology in general, an imaging study must enable accurate measurements, demonstrate intraluminal abnormalities and
mural disease, and depict (patency of) side branches
[1]. Evaluation of vascular disease is facilitated by 3D
techniques, and improves appreciation of the geometry
of vascular structures and lesions. The currently available imaging modalities that allow for 3D evaluation of
the thoracic aorta are multidetector row CTA, contrastenhanced MRA and 3D-RA.
1.2.1 Multidetector Row CTA
Compared with single-slice CT the scanning speed of
multidetector row CT has increased 40-fold, which
makes it possible to scan the entire thorax in a short
breath-hold. The present generation of multidetector
row or multislice CT scanners allows for a simultaneous
acquisition of up to 16 slices, while in the near future
systems with over 64 detectors will become available.
With multidetector row CT a single acquisition yields a
volume of data, instead of a number of slices (as when
using helical CT). Thusfar resolution in the z-axis
(ªslice thicknessº) was a limiting factor in image quality
for multiplanar reconstruction (MPR). With an increase
of the number of detectors, the resolution increases as
well, and thus (near) isotropic imaging becomes possible (i.e., imaging with a resolution that is equally high
in all directions).

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I. State of the Art
It has been demonstrated that in order to get optimal enhancement of the thoracic aorta preferably highconcentration contrast medium should be used (more
than 300 mg I/ml), followed by flushing with a saline
bolus [2±4]. The scan delay can be optimized, and the
contrast medium dose can be reduced by using a testbolus technique, or by using an automatic bolus recognition system (bolus triggering) [3]. Scanning protocols
vary with different systems and manufacturers. With a
four-row detector most examinations are performed
with 2.5-mm collimation and a table speed of 15±
20 mm per rotation, while using a 16-row detector collimation is reduced to 1.5 mm, and the table speed can
be increased to 36 mm per rotation. Contrast medium
is injected at a flow-rate of 3±5 ml/s, for a total volume
of 120 ml.
The radiation dose for CTA is at least 2±3 times lower than the dose for angiography [5].
Anatomic coverage should include the thoracic inlet
(in order to evaluate congenital anomalies of the supraaortic arches) and the diaphragm (which can help to
determine the side of the descending aorta) [5].
3D volume-rendering techniques permit real-time,
interactive evaluation in any plane and projection. This
enhances understanding of vessel dilatation, mural
thrombus and branch vessel anatomy, and further allows visualization of both vascular structures and adjacent viscera and airways [1, 5]. After obtaining the volumetric data set, a number of postprocessing image reconstruction options are available [5]:
l MPR: 2D sections with a thickness of 1 voxel (fast,
easily performed at the CT scanner).
l Variable-thickness displays consisting of an assimila-
tion of various sections.
l Maximum-intensity projection (MIP) in which
images are derived by projecting the highest attenua-
tion voxel in a ray through the scan volume onto an
image plane; vessels running in close proximity of
osseous structures or calcifications can be easily ob-
scured.
l Shaded surface display: this method uses a single
threshold to choose relevant (high-density) voxels;
because of the threshold this method is susceptible
to artifacts, and may fail to demonstrate vascular
calcifications.
l 3D volume-rendering techniques (require a separate
workstation): each voxel is adjusted for opacity, color
and brightness according to each CT value, accord-
ing to preset color and opacity maps; the advantage
of this technique is that no threshold levels are being
selected, thus avoiding the possibility of altering ap-
parent diameters of vessels [6].
Reversing the window-level transfer function, we can
produce virtual angioscopic images [7, 8].
In summary the advantages of multidetector row CT
include shorter imaging time, greater axial coverage,
motion artifact suppression, improved z-axis resolution,
higher axial spatial resolution, decreased total dose of
iodinated contrast medium and real-time interactive 3D
display facilities on workstations.
1.2.2 MR Angiography
Traditionally, MRI, using T1-weighted spin-echo (black
blood) imaging and cine-MRI is well suited for evaluation of the gross anatomy of the thoracic aorta, as well
as for evaluation of pericardial, pleural and mediastinal
effusions [9]. Flow-based methods of imaging (using
time-of-flight or phase-contrast properties) yield bright
blood images using gradient-echo techniques [10]. The
limitation of the latter techniques, however, is that they
rely on the physical properties of flowing blood (velocity, direction, etc.), making the technique susceptible
for artifacts, which may result in overestimation of stenoses or even a false diagnosis of occlusion of a vessel.
Furthermore the spatial resolution and signal-to-noise
ratio provided by these 2D techniques do not allow
evaluation of small vessel lesions or small side branches
[11].
The most-suited technique currently used in the
evaluation of thoracic aortic anatomy and disease is dynamic subtraction MRA, using gadolinium (0.2 mmol/
kg, flow rate of antecubital injection 2 ml/s) as the intravenous contrast agent [10, 12±16]. Gadolinium shortens the T1 of blood, and therefore allows shorter imaging times. Thus, fewer flow-related and motion-related
artifacts occur, and therefore the technique can demonstrate subtle aortic lesions, such as penetrating ulcers,
and small intercostal arteries. After a plain MRI, intravenous contrast agent is administered. Using bolus timing (either by using a test bolus or real-time fluoroscopic triggering) the arrival of the contrast agent can
be timed, and the contrast-enhanced sequence is performed [10, 17]. This is followed by subtraction of the
two series. The limitation of this test-bolus technique is
the potential for diminished artery-to-vein contrast, associated additional cost of test-bolus contrast and the
potential difficulty to observe the test bolus in distal
vessels or in cases with slow flow [17]. To further reduce respiratory motion artifacts and artifacts related
to cardiac motion and pulsatile flow, electrocardiographic triggering techniques can be used [9, 18]. The
images thus obtained can either be viewed on a sliceto-slice basis, or can be reconstructed on a computer
workstation into a MIP image. The appearance of MIP
reconstructions resembles that of conventional angiography, and MIP reconstructions are therefore useful in
planning of surgical procedures [13]. Using 3D reconstruction techniques it is also possible to obtain an internal view of the vessel and its walls (virtual intra-arterial endoscopy) [13]. It is of importance to evaluate

Jos C. van den Berg Chapter 1 Radio-Anatomy of the Thoracic Aorta. 3D Imaging of the Aorta (CT, MRI and 3D Rotational Angiography)
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5
both source images and reconstructed images, in order
to optimize diagnostic yield (e.g., a dissection can be
easily overlooked by evaluating MIP images alone) [18].
Scanning parameters may vary depending on the
type and the manufacturer of the MRI system, and will
not be listed here.
1.2.3 3D Rotational Angiography
Conventional rotational angiography images are obtained by performing a motorized movement at constant speed of the C-arm around the patient during
continuous contrast agent injection. To obtain 3D
images from a conventional rotational angiographic run
two methods exist. One consists of an examination in
two phases, where at first the C-arm makes a sweep, acquiring images that act as a mask for the subsequent
data acquisition. Subsequently a return sweep is performed while contrast agent is injected throughout the
entire period of data acquisition [19, 20].
The other technique of obtaining 3D-RA images is
directly based on conventional rotational angiographic
images without the use of subtraction [21±23].
With both techniques images are transferred to a
workstation, where they are converted into pseudo-CT
slices (the image intensifier being considered a multiline detector). Using specific algorithms that correct for
image intensifier and contrast distortion, the data set is
reconstructed into a volume-rendered image. During
this reconstruction process two different types of image
correction are performed to limit visual distortion to a
minimum: pincushion distortion correction, which is
used for reducing the environmental influences caused
by the earth`s magnetic field, and isocenter correction,
which corrects all the movement imperfections introduced by the rotating C-arm [24]. The 3D volume obtained in this way can be rotated and viewed in any direction, and optimal tube positioning (angulation,
skew) can be chosen. Determination of vessel geometrical properties (length, diameter) can be done manually
or using automated vessel analysis software. This software can also provide an endoscopic view (virtual angioscopy), used for evaluation of the vessel interior. Recent developments in software, using an unenhanced
and a contrast-enhanced run, also allow visualization of
calcifications. The same method can provide an improved depiction of stent location and its relation to the
calcified plaque and vessel wall. Important information
on flow characteristics can be gathered from the cinefluoroscopic angiographic images.
A disadvantage of the 3D-RA technique is nonvisualization of the thrombus. The same is true for conventional angiography. Calcification, however, can be demonstrated using 3D-RA using either the source images
showing some indirect signs of the presence of a
Table 1.1 Advantages and disadvantages of the various three-
dimensional imaging techniques
Feature of technique CTA CE-MRA 3D-RA
Diameter measurements + + +
Demonstration of thrombus + + ±
Demonstration of calcification + Ô +
Demonstration of vessel wall + + ±
Intraluminal detail + + ±
Branch vessels + + +
Dynamic flow information ± ± +
Monitoring intervention ± ± +
CTA computerized tomography angiography, CE-MRA contrastenhanced magnetic resonance angiography, 3D-RA 3D rotational angiography
thrombus (discrepancy between angiographic lumen
and location of calcification) or the calcified plaque
software.
The main use of 3D-RA is in a therapeutic setting in
the interventional suite. Use as a diagnostic modality in
cases with complex anatomy is another field of application of 3D-RA. The major advantage of 3D-RA is that
owing to the short reconstruction times the physician
can optimize projection and make adjustments during
the interventional procedure, in order to ensure the optimal outcome, without additional procedure time.
Table 1.1 lists advantages and disadvantages of the
various three-dimensional imaging techniques.
1.3 Gross Anatomy
The thoracic aorta starts at the level of the aortic valves
in the right anterior mediastinum. The aortic root is
formed by the three sinuses of Valsalva (Fig. 1.1).
The ascending thoracic aorta then follows an upward
and subsequent left laterodorsal course through the thoracic cavity and is continuous with the aortic arch. The
aortic arch has the shape of a semicircle, and slightly
ventral to the vertex it gives off its three largest
branches (innominate artery, left common carotid artery and left subclavian artery). Finally it makes a
downward turn as the descending thoracic aorta. The
transition of the aortic arch to the descending thoracic
aorta lies at the level of the isthmus (insertion of the ligamentum arteriosum, the remainder of the ductus Botalli). At the level of the diaphragm the aorta starts its
abdominal course. The diameter of the thoracic aorta
normally measures 3.3 cm at the aortic root, 3.0 cm at
the mid-ascending portion, 2.7 cm at the level of the
aortic arch and 2.4 cm at the proximal descending aorta
[25]. Along the course of the thoracic aorta several side
branches originate, and these are described in the following.

6
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I. State of the Art
ab
cd
Fig. 1.1. a Axial computerized tomography (CT) at the level of
the aortic sinus (arrow). The trilobar appearance is clearly
appreciated; part of the main stem of the left coronary artery
is clearly seen (arrowhead).
than in a demonstrating the origin of the right coronary artery
(arrow).
of aortic valves (arrow).
c Axial CT at a level below that in b depicting cusps
1.3.1 Coronary arteries
The left main coronary artery arises from the left posterior Valsalva sinus and divides into the left anterior or
descending artery (running to the left of the common
trunk of the pulmonary artery and the left circumflex
artery (following the left atrio-ventricular groove)
(Fig. 1.2). The right coronary artery originates from the
b Axial CT at a slightly lower level
d Axial CT at the level of the common
trunk of the pulmonary artery (asterisk) demonstrating the site
of anastomosis (arrow) of the aorto-coronary bypass graft (ar-
rowhead).
(MPR) demonstrating the full course of the bypass graft (ar-
row). f Volume-rendering technique (VRT) image depicting a
aorto-coronary bypass graft to advantage (arrow)
e Curved reformatted multiplanar reconstruction
right anterior coronary sinus, caudally from the left coronary artery and prior to giving of its first branch
(conus artery) it runs rightward posterior and inferiorly. With optimization of spatial resolution, decreasing scanning time and proper cardiac gating, these four
main coronary arteries can be visualized using CT [26,
27] and MRI [28].
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