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List of Contributors
Philippe Cluzel
Radiology Department Groupe Hospitalier Piti-Salptrire 47±83 bd de l'HÖpital 75013 Paris France
Alain Cerene
Department of Cardiovascular Surgery Rangueil University Hospital 1 av J. Poulhes ± TSA 50032 31059 Toulouse CEDEX 9 France
C. Cron
Department of Cardio Vascular Surgery University Hospital Rangueil 01 av J Poulhes 31403 Toulouse France
Michael D. Dake
University of Virginia Health System Charlottesville, VA 22908-0170 USA
Camille Dambrin
Department of Cardiovascular Surgery Rangueil University Hospital 1 av J. Poulhes ± TSA 50032 31059 Toulouse CEDEX 9 France
Bertrand De Latour
Cardiovascular and Thoracic Surgery Department University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Gabriel Delorme
Cardiology Department HÖpital Ambroise Par 9 av Charles de Gaulle 92100 Boulogne Billancourt France
Karl Dossche
St. Antonius Hospital Department of Cardiothoracic Surgery Koekoekslaan 1 3435 CM Nieuwegein The Netherlands
Chris Elkins
Departments of Mechanical Engineering and Radiology Stanford University Stanford, CA 94305 USA
Anthony L. Estrera
Department of Cardiothoracic and Vascular Surgery The University of Texas at Houston Medical School 6410 Fannin, Suite 450, CV Surgery Houston, TX 77030 USA
Artur Evangelista
Department of Cardiac Imaging Cardiology Department Hospital Universitari Vall d'Hebron Barcelona Spain
Rosella Fattori
Cardiovascular Unit Department of Radiology S. Orsola University Hospital Bologna Italy
Jeffrey A. Feinstein
Pediatrics Division of Pediatric Cardiology Associate Director Pediatric and Congenital Cardiac Catheterization Lucile Packard Children's Hospital Stanford University Medical Center 750 Welch Road, Suite 305 Palo Alto, CA 94304 USA
Gerard Fournial
Department of Cardiovascular Surgery CHU Rangueil Toulouse France
JoaquÌn FerreirÕs
Departamento de RadiologÌa Hospital Universitario de San Carlos Madrid Spain
Virginia Gaxotte
Service de Radiologie et d'Imagerie Cardio-vasculaire HÖpital Cardiologique ± CHRU de Lille Bd du Professeur Leclerc 59037 Lille CEDEX France
List of Contributors
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XIII
Betti Giusti
Department of Medical and Surgical Critical Care Thrombosis Centre and Centre for the Study at Molecular and Clinical Level of Chronic, Degenerative and Neoplastic Diseases to Develop Novel Therapies (DENOTHE) University of Florence Viale Morgagni 85 50134 Florence Italy
Teresa Gonzlez-Alujas
Echocardiography Cardiology Department Hospital Universitari Vall d'Hebron Barcelona Spain
Randall Griepp
Department of Cardiothoracic Surgery Mount Sinai Medical Center 1190 Fifth Avenue, Box 1028 New York, NY 10029 USA
Jean Philippe Guibaud
Department of Cardiovascular and Paediatric Cardiac Surgery Bordeaux Heart University Hospital Avenue de Magellan 33604 Pessac France
Jean-Franois Heautot
Radiology and Medical Imaging Department University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Tadanori Hirano
Department of Radiology Matsusaka Central General Hospital 102 Kawai, Matsusaka Mie 515-8566 Japan
Hiroaki Hosokawa
Department of Clinical Research National Hospital Organization Toyohashi Hospital Aichi Japan
Tam T.T. Huynh
Department of Cardiothoracic and Vascular Surgery The University of Texas at Houston Medical School 6410 Fannin, Suite 450, CV Surgery Houston, TX 77030 USA
Kanji Inoue
PTMC Institute 39-1 Sakurai-Cho, Kamigamo Kita-Ku, Kyoto 603-8054 Japan and
Clinical Department of Cardiovascular Surgery Faculty of Medicine Kyoto University Shimabara Hospital 7-4 Kosaka-Cho, Shimokyo-Ku Kyoto, 600-8821 Japan
Krassi Ivancev
Endovascular Center Malmæ University Hospital 20502 Malmæ Sweden
Michael J. Jacobs
Department of Surgery University Hospital Maastricht P.O. Box 5800 6202 AZ Maastricht The Netherlands
Patrick Jgo
Internal Medicine Unit HÖpital Sud 16 boulevard de Bulgarie 35203 Rennes France
Francis Joffre
Department of Radiology Rangueil University Hospital 1 av J. Poulhes ± TSA 50032 31059 Toulouse CEDEX 9 France
Guillaume Jondeau
Consultation Multidisciplinaire Marfan HÖpital Ambroise Par 9 Av Charles de Gaulle 92100 Boulogne Billancourt France
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List of Contributors
Cyryl Kakon
Cardiovascular and Thoracic Surgery Department University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Matthias Karck
Division of Thoracic and Cardiovascular Surgery Hannover Medical School Carl-Neuberg-Str. 1 30625 Hannover Germany
Noriyuki Kato
Department of Radiology Mie University Hospital 2-174 Edobashi, Tsu Mie 514-8507 Japan
Nawid Khaladj
Division of Thoracic and Cardiovascular Surgery Hannover Medical School Carl-Neuberg-Str. 1 30625 Hannover Germany
Takeshi Kimura
Department of Cardiovascular Medicine Graduate School of Medicine Kyoto University and Director Division of Clinical Cardiology Kyoto University Hospital Kyoto Japan
Francois G. Lacour-Gayet
Pediatric Cardiac Surgery The Children's Hospital Heart Institute 1056 East 19th Avenue, B200 Denver, CO 80218-1088 USA
John F. LaDisa Jr.
Pediatrics Division of Cardiology Stanford University Medical Center 750 Welch Road, Suite 305 Palo Alto, CA 94304 USA
Thierry Langanay
Cardiovascular and Thoracic Surgery Department University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Do Yun Lee
Department of Diagnostic Radiology Yonsei University College of Medicine 134 Shinchon-dong Seodaemun-gu Seoul 120-752 Korea
Alain Leguerrier
Cardiovascular and Thoracic Surgery Department University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Bansi Koul
Department of Cardiothoracic Surgery University Hospital of Lund 22185 Lund Sweden
Louis Labrousse
Department of Cardiac and Vascular Surgery HÖpital Haut-Lvque Bordeaux University Hospital 33604 Pessac CEDEX France
B. Leobon
Department of Cardio Vascular Surgery University Hospital Rangueil 01 av J Poulhes 31403 Toulouse France
Pascal Leprince
CT Surgery Department Groupe Hospitalier Piti-Salptrire 47±83 bd de l'HÖpital 75013 Paris France
List of Contributors
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XV
Christophe Lions
Service de Radiologie et d'Imagerie Cardio-vasculaire HÖpital Cardiologique ± CHRU de Lille Bd du Professeur Leclerc 59037 Lille CEDEX France
Bertrand Marcheix
Department of Cardiovascular Surgery Rangueil University Hospital 1 av J. Poulhes ± TSA 50032 31059 Toulouse CEDEX 9 France
Pierre Massabuau
Department of Cardiology Rangueil University Hospital 1 av J. Poulhes ± TSA 50032 31059 Toulouse CEDEX 9 France
Genevive Meites
Dpartement d'Anesthsie Ranimation Centre Hospitalier Universitaire 31059 Toulouse France
Charles C. Miller III
Center for Clinical Research and Evidence-Based Medicine Center for Biotechnology Department of Cardiothoracic and Vascular Surgery The University of Texas at Houston Medical School 6410 Fannin, Suite 450, CV Surgery Houston, TX 77030 USA
Olivier Milleron
Cardiology Department HÖpital Ambroise Par 9 av Charles de Gaulle 92100 Boulogne Billancourt France
R. Scott Mitchell
Department of Cardiothoracic Surgery Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305 USA
Ziad Negaiwi
Service de Radiologie et d'Imagerie Cardio-vasculaire HÖpital Cardiologique ± CHRU de Lille Bd du Professeur Leclerc 59037 Lille CEDEX France
Christoph A. Nienaber
Division of Cardiology University Hospital Rostock Rostock School of Medicine Ernst-Heydemann-Str. 6 18057 Rostock Germany
Philippe Otal
Department of Radiology Rangueil University Hospital 1 av J. Poulhes ± TSA 50032 31059 Toulouse CEDEX 9 France
Davide Pacini
Department of Cardiac Surgery S. Orsola University Hospital Bologna Italy
Alain Pavie
CT Surgery Department Groupe Hospitalier Piti-Salptrire 47±83 bd de l'HÖpital 75013 Paris France
Oliver Pellerin
Department of Cardiovascular and Interventional Radiology HÖpital Europen Georges Pompidou 75015 Paris France
Guglielmina Pepe
Department of Medical and Surgical Critical Care Thrombosis Centre and Centre for the Study at Molecular and Clinical Level of Chronic, Degenerative and Neoplastic Diseases to Develop Novel Therapies (DENOTHE) University of Florence Viale Morgagni 85 50134 Florence Italy
Bora Peynircioglu
Section of Vascular/Interventional Radiology Department of Radiology School of Medicine Hacettepe University Ankara Turk ey
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List of Contributors
Eyal E. Porat
Department of Cardiothoracic and Vascular Surgery The University of Texas at Houston Medical School 6410 Fannin, Suite 450, CV Surgery Houston, TX 77030 USA
Maria Cristina Porciani
Department of Medical and Surgical Critical Care University of Florence Viale Morgagni 85 50134 Florence Italy
Alain Prat
Cardiac and Vascular Surgery Unit HÖpital Cardiologique ± CHRU de Lille Bd du Professeur Leclerc 59037 Lille CEDEX France
Matthieu Revest
Internal Medicine Unit HÖpital Sud 16 Boulevard de Bulgarie 35203 Rennes France
Xavier Roques
Department of Cardiovascular and Paediatric Cardiac Surgery Bordeaux Heart University Hospital Avenue de Magellan 33604 Pessac France
Herv Rousseau
Department of Radiology Rangueil University Hospital 1 av J. Poulhes ± TSA 50032 31059 Toulouse CEDEX 9 France
Hazim J. Safi
Department of Cardiothoracic and Vascular Surgery The University of Texas at Houston Medical School 6410 Fannin, Suite 450, CV Surgery Houston, TX 77030 USA
Jos Alberto San Romn
ICICOR ± Instituto de las Ciencias del CorazÕn Hospital Universitario de Valladolid Valladolid Spain
Marc Sapoval
Facult de Mdecine Ren Descartes Paris 5 Department of Cardiovascular and Interventional Radiology HÖpital Europen Georges Pompidou 75015 Paris France
Hans-Joachim Schåfers
Department of Thoracic and Cardiovascular Surgery Universitåtsklinikum des Saarlandes Kirrbergerstr. 1 66424 Homburg/Saar Germany
Marc Schepens
St. Antonius Hospital Department of Cardiothoracic Surgery Koekoekslaan 1 3435 CM Nieuwegein The Netherlands
Michel Sellin
Service d'Anesthsie Ranimation 2 University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Takatsugu Shimono
Department of Thoracic and Cardiovascular Surgery Mie University Hospital 2-174 Edobashi, Tsu Mie 514-8507 Japan
David Spielvogel
New York Medical College Valhalla, NY 10595 USA
Charles A. Taylor
Mechanical Engineering Bioengineering, Surgery, Pediatrics (by courtesy) & Radiology (by courtesy) Stanford University Medical Center 750 Welch Road, Suite 305 Palo Alto, CA 94304 USA
Frdric Thony
Service Central de Radiologie et Imagerie Mdicale CHU ± Scrim BP 217, 38043 Grenoble 9 France
List of Contributors
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XVII
Vincent Tran Dinh
Radiology and Medical Imaging Department University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Jos C. van den Berg
Service of Interventional Radiology Ospedale Regionale di Lugano sede Civico Via Tesserete 46 6900 Lugano Switzerland
Pieter J. A. van der Starre
Department of Anesthesia Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305 USA
Jean-Philippe Verhoye
Cardiovascular and Thoracic Surgery Department University Hospital Center of Rennes Pontchaillou Hospital Rue Henri Le Guillou 35033 Rennes CEDEX 9 France
Isidre Vilacosta
Cardiology Instituto Cardiovascular Hospital Universitario de San Carlos Madrid Spain
David M. Williams
Vascular and Interventional Radiology University of Michigan Hospitals Ann Arbor, MI 48109-0030 USA
Jessica Wilson
Cardiology Department HÖpital Ambroise Par 9 av Charles de Gaulle 92100 Boulogne Billancourt France
Serge Willoteaux
Service de Radiologie et d'Imagerie Cardio-vasculaire HÖpital Cardiologique ± CHRU de Lille Bd du Professeur Leclerc 59037 Lille CEDEX France
Jong Yun Won
Department of Diagnostic Radiology Yonsei University College of Medicine 134 Shinchon-dong, Seodaemun-gu Seoul 120-752 Korea
Sir Magdi Yacoub
Cardiothoracic Surgery Imperial College London Heart Science Centre Harefield Middlesex, UB9 6JH UK
David S. Wang
Howard Hughes Medical Institute Fellow Section of Cardiovascular and Interventional Radiology Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305 USA
Radio-Anatomy
https://t.me/med1917
of the Thoracic Aorta. 3D Imaging of the Aorta (CT, MRI and 3D Rotational Angiography)
Jos C. van den Berg
Chapter
1
Contents
1.1 Introduction .......................
1.2 Imaging Modalities ................... 3
1.2.1 Multidetector Row CTA ............. 3
1.2.2 MR Angiography ................. 4
1.2.3 3D Rotational Angiography ........... 5
1.3 GrossAnatomy ...................... 5
1.3.1 Coronary arteries ................ 6
1.3.2 Supra-aortic Vessels ............... 7
1.3.3 Intercostal Arteries ............... 8
1.3.4 Anterior Spinal Artery ............. 8
1.3.5 Bronchial Arteries ................ 8
1.4 Congenital Variants and Abnormalities ........ 10
1.4.1 Coronary Arteries ................ 10
1.4.2 Supra-aortic Vessels and Aortic Arch ..... 10
1.4.3 aortic Coarctation ................ 13
1.5 Acquired Aortic Disease ................. 15
1.5.1 Dissection ..................... 15
1.5.2 Aneurysms .................... 15
1.6 Conclusions ........................ 17
1.1 Introduction
Traditionally radiological imaging of the human body has been limited to a two-dimensional depiction of a three-dimensional reality. The thoracic aorta modalities most commonly used were plain (chest) radiography, (digital subtraction) angiography and single-slice com­puterized tomography (CT). Over the last decade tre­mendous technical advancements have been made in various imaging modalities. The speed of data acquisi­tion with CT scanning and MRI has increased, thus en­abling fast, high-resolution axial imaging. The concur­rent development of advanced 3D volume-rendering techniques, which require high computational speed, al­lowed for the development of CT angiography (CTA), magnetic resonance angiography (MRA) and 3D rota­tional angiography (3D-RA). In this chapter a brief
overview on the technical aspects of the currently avail­able modalities will be given and advantages and disad-
3
vantages of each technique will be discussed. The radio­logical anatomy of the thoracic aorta and its branches as depicted with these new imaging techniques will be described in detail.
1.2 Imaging Modalities
For successful evaluation of vascular pathology in gen­eral, an imaging study must enable accurate measure­ments, demonstrate intraluminal abnormalities and mural disease, and depict (patency of) side branches [1]. Evaluation of vascular disease is facilitated by 3D techniques, and improves appreciation of the geometry of vascular structures and lesions. The currently avail­able imaging modalities that allow for 3D evaluation of the thoracic aorta are multidetector row CTA, contrast­enhanced MRA and 3D-RA.
1.2.1 Multidetector Row CTA
Compared with single-slice CT the scanning speed of multidetector row CT has increased 40-fold, which makes it possible to scan the entire thorax in a short breath-hold. The present generation of multidetector row or multislice CT scanners allows for a simultaneous acquisition of up to 16 slices, while in the near future systems with over 64 detectors will become available. With multidetector row CT a single acquisition yields a volume of data, instead of a number of slices (as when using helical CT). Thusfar resolution in the z-axis (ªslice thicknessº) was a limiting factor in image quality for multiplanar reconstruction (MPR). With an increase of the number of detectors, the resolution increases as well, and thus (near) isotropic imaging becomes possi­ble (i.e., imaging with a resolution that is equally high in all directions).
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I. State of the Art
It has been demonstrated that in order to get opti­mal enhancement of the thoracic aorta preferably high­concentration contrast medium should be used (more than 300 mg I/ml), followed by flushing with a saline bolus [2±4]. The scan delay can be optimized, and the contrast medium dose can be reduced by using a test­bolus technique, or by using an automatic bolus recog­nition system (bolus triggering) [3]. Scanning protocols vary with different systems and manufacturers. With a four-row detector most examinations are performed with 2.5-mm collimation and a table speed of 15± 20 mm per rotation, while using a 16-row detector colli­mation is reduced to 1.5 mm, and the table speed can be increased to 36 mm per rotation. Contrast medium is injected at a flow-rate of 3±5 ml/s, for a total volume of 120 ml.
The radiation dose for CTA is at least 2±3 times low­er than the dose for angiography [5].
Anatomic coverage should include the thoracic inlet (in order to evaluate congenital anomalies of the supra­aortic arches) and the diaphragm (which can help to determine the side of the descending aorta) [5].
3D volume-rendering techniques permit real-time, interactive evaluation in any plane and projection. This enhances understanding of vessel dilatation, mural thrombus and branch vessel anatomy, and further al­lows visualization of both vascular structures and adja­cent viscera and airways [1, 5]. After obtaining the vo­lumetric data set, a number of postprocessing image re­construction options are available [5]:
l MPR: 2D sections with a thickness of 1 voxel (fast,
easily performed at the CT scanner).
l Variable-thickness displays consisting of an assimila-
tion of various sections.
l Maximum-intensity projection (MIP) in which
images are derived by projecting the highest attenua-
tion voxel in a ray through the scan volume onto an
image plane; vessels running in close proximity of
osseous structures or calcifications can be easily ob-
scured.
l Shaded surface display: this method uses a single
threshold to choose relevant (high-density) voxels;
because of the threshold this method is susceptible
to artifacts, and may fail to demonstrate vascular
calcifications.
l 3D volume-rendering techniques (require a separate
workstation): each voxel is adjusted for opacity, color
and brightness according to each CT value, accord-
ing to preset color and opacity maps; the advantage
of this technique is that no threshold levels are being
selected, thus avoiding the possibility of altering ap-
parent diameters of vessels [6].
Reversing the window-level transfer function, we can produce virtual angioscopic images [7, 8].
In summary the advantages of multidetector row CT include shorter imaging time, greater axial coverage,
motion artifact suppression, improved z-axis resolution, higher axial spatial resolution, decreased total dose of iodinated contrast medium and real-time interactive 3D display facilities on workstations.
1.2.2 MR Angiography
Traditionally, MRI, using T1-weighted spin-echo (black blood) imaging and cine-MRI is well suited for evalua­tion of the gross anatomy of the thoracic aorta, as well as for evaluation of pericardial, pleural and mediastinal effusions [9]. Flow-based methods of imaging (using time-of-flight or phase-contrast properties) yield bright blood images using gradient-echo techniques [10]. The limitation of the latter techniques, however, is that they rely on the physical properties of flowing blood (velo­city, direction, etc.), making the technique susceptible for artifacts, which may result in overestimation of ste­noses or even a false diagnosis of occlusion of a vessel. Furthermore the spatial resolution and signal-to-noise ratio provided by these 2D techniques do not allow evaluation of small vessel lesions or small side branches [11].
The most-suited technique currently used in the evaluation of thoracic aortic anatomy and disease is dy­namic subtraction MRA, using gadolinium (0.2 mmol/ kg, flow rate of antecubital injection 2 ml/s) as the in­travenous contrast agent [10, 12±16]. Gadolinium short­ens the T1 of blood, and therefore allows shorter imag­ing times. Thus, fewer flow-related and motion-related artifacts occur, and therefore the technique can demon­strate subtle aortic lesions, such as penetrating ulcers, and small intercostal arteries. After a plain MRI, intra­venous contrast agent is administered. Using bolus tim­ing (either by using a test bolus or real-time fluoro­scopic triggering) the arrival of the contrast agent can be timed, and the contrast-enhanced sequence is per­formed [10, 17]. This is followed by subtraction of the two series. The limitation of this test-bolus technique is the potential for diminished artery-to-vein contrast, as­sociated additional cost of test-bolus contrast and the potential difficulty to observe the test bolus in distal vessels or in cases with slow flow [17]. To further re­duce respiratory motion artifacts and artifacts related to cardiac motion and pulsatile flow, electrocardio­graphic triggering techniques can be used [9, 18]. The images thus obtained can either be viewed on a slice­to-slice basis, or can be reconstructed on a computer workstation into a MIP image. The appearance of MIP reconstructions resembles that of conventional angio­graphy, and MIP reconstructions are therefore useful in planning of surgical procedures [13]. Using 3D recon­struction techniques it is also possible to obtain an in­ternal view of the vessel and its walls (virtual intra-arte­rial endoscopy) [13]. It is of importance to evaluate
Jos C. van den Berg Chapter 1 Radio-Anatomy of the Thoracic Aorta. 3D Imaging of the Aorta (CT, MRI and 3D Rotational Angiography)
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5
both source images and reconstructed images, in order to optimize diagnostic yield (e.g., a dissection can be easily overlooked by evaluating MIP images alone) [18].
Scanning parameters may vary depending on the type and the manufacturer of the MRI system, and will not be listed here.
1.2.3 3D Rotational Angiography
Conventional rotational angiography images are ob­tained by performing a motorized movement at con­stant speed of the C-arm around the patient during continuous contrast agent injection. To obtain 3D images from a conventional rotational angiographic run two methods exist. One consists of an examination in two phases, where at first the C-arm makes a sweep, ac­quiring images that act as a mask for the subsequent data acquisition. Subsequently a return sweep is per­formed while contrast agent is injected throughout the entire period of data acquisition [19, 20].
The other technique of obtaining 3D-RA images is directly based on conventional rotational angiographic images without the use of subtraction [21±23].
With both techniques images are transferred to a workstation, where they are converted into pseudo-CT slices (the image intensifier being considered a multi­line detector). Using specific algorithms that correct for image intensifier and contrast distortion, the data set is reconstructed into a volume-rendered image. During this reconstruction process two different types of image correction are performed to limit visual distortion to a minimum: pincushion distortion correction, which is used for reducing the environmental influences caused by the earth`s magnetic field, and isocenter correction, which corrects all the movement imperfections intro­duced by the rotating C-arm [24]. The 3D volume ob­tained in this way can be rotated and viewed in any di­rection, and optimal tube positioning (angulation, skew) can be chosen. Determination of vessel geometri­cal properties (length, diameter) can be done manually or using automated vessel analysis software. This soft­ware can also provide an endoscopic view (virtual an­gioscopy), used for evaluation of the vessel interior. Re­cent developments in software, using an unenhanced and a contrast-enhanced run, also allow visualization of calcifications. The same method can provide an im­proved depiction of stent location and its relation to the calcified plaque and vessel wall. Important information on flow characteristics can be gathered from the cine­fluoroscopic angiographic images.
A disadvantage of the 3D-RA technique is nonvisua­lization of the thrombus. The same is true for conven­tional angiography. Calcification, however, can be dem­onstrated using 3D-RA using either the source images showing some indirect signs of the presence of a
Table 1.1 Advantages and disadvantages of the various three-
dimensional imaging techniques
Feature of technique CTA CE-MRA 3D-RA
Diameter measurements + + + Demonstration of thrombus + + ± Demonstration of calcification + Ô + Demonstration of vessel wall + + ± Intraluminal detail + + ± Branch vessels + + + Dynamic flow information ± ± + Monitoring intervention ± ± +
CTA computerized tomography angiography, CE-MRA contrast­enhanced magnetic resonance angiography, 3D-RA 3D rota­tional angiography
thrombus (discrepancy between angiographic lumen and location of calcification) or the calcified plaque software.
The main use of 3D-RA is in a therapeutic setting in the interventional suite. Use as a diagnostic modality in cases with complex anatomy is another field of applica­tion of 3D-RA. The major advantage of 3D-RA is that owing to the short reconstruction times the physician can optimize projection and make adjustments during the interventional procedure, in order to ensure the op­timal outcome, without additional procedure time.
Table 1.1 lists advantages and disadvantages of the various three-dimensional imaging techniques.
1.3 Gross Anatomy
The thoracic aorta starts at the level of the aortic valves in the right anterior mediastinum. The aortic root is formed by the three sinuses of Valsalva (Fig. 1.1).
The ascending thoracic aorta then follows an upward and subsequent left laterodorsal course through the tho­racic cavity and is continuous with the aortic arch. The aortic arch has the shape of a semicircle, and slightly ventral to the vertex it gives off its three largest branches (innominate artery, left common carotid ar­tery and left subclavian artery). Finally it makes a downward turn as the descending thoracic aorta. The transition of the aortic arch to the descending thoracic aorta lies at the level of the isthmus (insertion of the li­gamentum arteriosum, the remainder of the ductus Bo­talli). At the level of the diaphragm the aorta starts its abdominal course. The diameter of the thoracic aorta normally measures 3.3 cm at the aortic root, 3.0 cm at the mid-ascending portion, 2.7 cm at the level of the aortic arch and 2.4 cm at the proximal descending aorta [25]. Along the course of the thoracic aorta several side branches originate, and these are described in the fol­lowing.
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I. State of the Art
ab
cd
Fig. 1.1. a Axial computerized tomography (CT) at the level of
the aortic sinus (arrow). The trilobar appearance is clearly appreciated; part of the main stem of the left coronary artery is clearly seen (arrowhead). than in a demonstrating the origin of the right coronary artery (arrow). of aortic valves (arrow).
c Axial CT at a level below that in b depicting cusps
1.3.1 Coronary arteries
The left main coronary artery arises from the left poste­rior Valsalva sinus and divides into the left anterior or descending artery (running to the left of the common trunk of the pulmonary artery and the left circumflex artery (following the left atrio-ventricular groove) (Fig. 1.2). The right coronary artery originates from the
b Axial CT at a slightly lower level
d Axial CT at the level of the common
trunk of the pulmonary artery (asterisk) demonstrating the site of anastomosis (arrow) of the aorto-coronary bypass graft (ar- rowhead). (MPR) demonstrating the full course of the bypass graft (ar- row). f Volume-rendering technique (VRT) image depicting a aorto-coronary bypass graft to advantage (arrow)
e Curved reformatted multiplanar reconstruction
right anterior coronary sinus, caudally from the left cor­onary artery and prior to giving of its first branch (conus artery) it runs rightward posterior and infe­riorly. With optimization of spatial resolution, decreas­ing scanning time and proper cardiac gating, these four main coronary arteries can be visualized using CT [26, 27] and MRI [28].