Добавил:
Sekretar
kiopkiopkiop18@yandex.ru
t.me/Prokururor I Вовсе не секретарь, но почту проверяю
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз:
Предмет:
Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_2894_Библиотеки_им_академика_М_И_Перельмана
.pdf
AmitSingh
DivakarSharmaEditors
Diagnosis
ofMycobacterium
Diagnosis of Mycobacterium
Amit Singh • Divakar Sharma
Editors
Diagnosis of Mycobacterium
Editors
Amit Singh
Department of Gastroenterology & HNU
All India Institute of Medical Sciences
New Delhi, India
Divakar Sharma
Department of Microbiology
Maulana Azad Medical College
New Delhi, India
ISBN 978-981-99-5623-4 ISBN 978-981-99-5624-1 (eBook)
https://doi.org/10.1007/978-981-99-5624-1
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore
Pte Ltd. 2023
This work is subject to copyright. All rights are solely and exclusively licensed by the Publisher, whether
the whole or part of the material is concerned, specically the rights of translation, reprinting, reuse of
illustrations, recitation, broadcasting, reproduction on microlms or in any other physical way, and
transmission or information storage and retrieval, electronic adaptation, computer software, or by similar
or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication
does not imply, even in the absence of a specic statement, that such names are exempt from the relevant
protective laws and regulations and therefore free for general use.
The publisher, the authors, and the editors are safe to assume that the advice and information in this book
are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the
editors give a warranty, expressed or implied, with respect to the material contained herein or for any
errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional
claims in published maps and institutional afliations.
This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd.
The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721,
Singapore
Paper in this product is recyclable.
Dedicated to
https://t.me/medicina_free
My teacher Prof. Sarman Singh for his
guidance, wisdom, and inspiration
My mother (late Smt. Somvati Singh), wife
(Dr. Arti) and daughter (Anaya) for their
love, support, and patience
Foreword
https://t.me/medicina_free
Dr. Amit Singh and Dr. Divakar Sharma deliver a highly useful work in the form
of a book entitled Diagnosis of Mycobacterium. This book contains a collection of
chapters on recent developments in the diagnosis of Mycobacterium from various
types of samples. The editors have recruited a vast array of tuberculosis specialists
to write different chapters that constitute this book. The chapters are structured in
such a way that the reader may easily nd pearls about tuberculosis diagnostics and
its applications to timely manage mycobacterium-related current issues, especially
drug resistance. I am sure researchers who are working in the elds of diagnosis of
mycobacterium and related research will nd this compilation useful and enjoyable.
Laboratory of Molecular Epidemiology
and Evolutionary Genetics
St. Petersburg Pasteur Institute,
St. Petersburg, Russia
IgorMokrousov
vii
Preface
https://t.me/medicina_free
Recent advancements in the eld of diagnostic biology have dramatically increased
the complexity of this eld. The diagnosis of mycobacterium is widely available
and plays an increasing role in the diagnosis and management of tuberculosis.
However, proper knowledge for recommending tests for the diagnosis of different
forms of tuberculosis is crucial for correct and timely diagnosis. Inappropriate
knowledge about the tests leads to delays in diagnosis, misinterpretation of results,
and hampers the management of mycobacterial infection, which can contribute to
the development of MDR and XDR tuberculosis. This book is the result of 15years
of working experience in the eld of tuberculosis research, diagnosis, and challenges. It stands out among other books as it specially focuses on the diagnosis of
mycobacterium in humans, pediatrics cases, zoonotic TB, and NTMs. This book
includes the most historic diagnosis, i.e., smear microscopy, clinical diagnosis,
radiological diagnosis to more advanced microbiological and molecular diagnosis
of TB infection. The diagnosis of latent TB infection is also addressed, which is
crucial for TB control. Since TB diagnostics are continuously evolving, the book
also includes future diagnostic techniques such as nano-biosensor-based diagnosis.
The mycobacterium diagnostic methods are still evolving and this book will be
helpful to upgrade the knowledge about the relevant diagnostic methods used for the
detection of mycobacterium from various clinical samples. Tremendous advances
have been made in the eld of diagnostics in the last few years, particularly resulting
from the introduction of molecular biology tools.
I have had the privilege of working and establishing a lab for the routine microbiological and molecular diagnosis of mycobacterium at the All India Institute of
Medical Sciences, New Delhi, and All India Institute of Medical Sciences, Bhopal,
under the guidance of eminent clinical microbiologist Prof. Sarman Singh who signicantly contributed to the eld of mycobacteriology. I was privileged to work
under his guidance. We believe that primarily in countries with high TB endemicity,
a quick and handy book on the diagnosis of mycobacterium is useful for microbiologists, clinicians, teachers, researchers, and PG and UG students of medicine and
microbiology.
ix
x
https://t.me/medicina_free
Preface
I wish to acknowledge the outstanding assistance from all the authors, contributors, colleagues, and physicians in the preparation of this book. Without them, this
book may not have been possible. I would also like to thank all the patients and
collaborators for their support from AIIMS, New Delhi, ICGEB, New Delhi, AIIMS,
Bhopal, and Delhi University for improving and developing newer diagnostics for
tuberculosis. Furthermore, I wish to thank all the helpful and kind people from the
publishers involved in the production of this book. We hope that our initiative will
inspire the interest of our microbiologists, physicians, students, and researchers not
only in the solution of TB clinical and laboratory diagnostics dilemmas but also
prompt them to present innovative queries on routine and basic diagnosis, nurturing
a continuous bidirectional exchange among the realms of health care and those of
clinical and basic research.
This book divided into several chapters. The rst chapter covers the basics of
various diagnostics of mycobacterium and then the clinical, radiological, pathological, biochemical, and hematological-based diagnostics. Moreover, it covers the
entire eld of mycobacterium diagnosis from microscopy to molecular tests, providing the latest content. However, the reader should consider that this eld is still
changing rapidly and day-to-day improvements and newer diagnostics will get
included. Suggestions for further improvements to be considered in future editions
are highly appreciated. Please contact the editor at amit4us@gmail.com, amit.
singh@cup.edu.in, divakarsharma88@gmail.com
Enjoy reading this new book!
New Delhi, India AmitSingh
DivakarSharma
Contents
https://t.me/medicina_free
1 Introduction to the Diagnosis of Mycobacterium . . . . . . . . . . . . . . . . 1
Amit Singh, Guru Dutta Satyarthee, and Divakar Sharma
2 Clinical and Radiological Diagnosis of Tuberculosis . . . . . . . . . . . . . . 11
Amber Kumar and Bhavna Dhingra
3 Pathology-Based Diagnosis of Tuberculosis . . . . . . . . . . . . . . . . . . . . . 25
Prabhakar Tiwari, Anjali Yadav, Rekha Dwivedi, Rekha Chaubey,
Daisy Rani Rasaily, Manjari Tripathi, Sandeep R. Mathur, and
Rima Dada
4 Assessment of Haematological and Biochemical Parameters
in the Diagnosis and Prognosis of Tuberculosis . . . . . . . . . . . . . . . . . . 39
Tushar Sehgal, Amit Singh, and Sudip Kumar Datta
5 Different Methods of Microscopic and Bacteriological Diagnosis
of Tuberculosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
Rupal Rai, Praveen Gautam, Bijina J. Mathew, Chandan Kumar
Dubey, Shadma Siddiqui, Sudheer Gupta, Shivendra K. Chaurasiya,
and Anirudh K. Singh
6 Molecular Diagnosis of Tuberculosis . . . . . . . . . . . . . . . . . . . . . . . . . . . 65
Sanjay Singh Negi, Pushpendra Singh, and Kuldeep Sharma
7 The Diagnosis and Challenges of Pediatric Tuberculosis . . . . . . . . . . 87
Alkesh Khurana and Bhavna Dhingra
8 Diagnosis of Latent Tuberculosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103
Parul Singh and Aishwarya Govindaswamy
9 The Future of Serology-Based Diagnosis for Tuberculosis
in India . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125
Anvita Gupta Malhotra, Anil Kumar Gupta, and Amit Singh
xi
xii
https://t.me/medicina_free
Contents
10 Point-of-Care (POC) Detection Technique for Mycobacterium . . . . . 145
Saumya Srivastava, Anil Kumar Gupta, Pawan Sharma, and
Amit Singh
11 Recent Developments in the Diagnosis and Treatment of
Non- Tuberculous Mycobacterial Infection . . . . . . . . . . . . . . . . . . . . . . 157
Shipra Tomar and Anand Kumar Maurya
12 Sensor and Nanotechnology-Based Diagnostics in the Field
of Mycobacteriology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 175
Mohanraj Thangarasu, Shunmuga Nathan Shunmuga Nainar,
Shakkthivel Piraman, and Vasantha Vairathevar Sivasamy
13 Nontuberculous Mycobacterium Infections in Lung Disease
and Medical Interventions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209
Anjana Suresh, Gayathri S. Kamath, Fidha Latheef, Greeshma
Sasikumar, and Sreejith Parameswara Panicker
14 Laboratory Diagnosis of Zoonotic Tuberculosis: An Update . . . . . . . 237
Anil Kumar Gupta, Amit Singh, Saumya Srivastava, Anvita Gupta
Malhotra, and Bipul Kumar
Соседние файлы в папке Библиотека им академика М.И. Перельмана