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Explainable AI Methods andApplications
45
5.4 Transportation
Navigational systems, autonomous vehicle decision support systems, and ight rerouting systems for the aviation sector are all included in the transportation area. Case-based explanations are ideal for autonomous automobile decision support sys­tems for domain specialists [4]. Case-based explanations involve relating a deci­sion’s justication to cases. Also, the explanations (hints) sent to the user can be in a hybrid manner: text, light indicators, or a visual format. The user criteria for navi­gation systems are slightly different since users need immediate explanations and proper justication for every decision. Flight rerouting systems show a similar pat­tern of behavior.
5.5 Finance
Insurance, nancial fraud detection, and loan applications are examples of XAI research’s nancial use cases. The operator should be able to see the loan request­or’s information, credit history, and other demographic information. It was also argued that when designing an explainable system, the developers must understand and connect with the user’s mental model. This is particularly important for banking activities like insurance claims and loan approvals. An efcient XAI system should be able to recognize the wrong mental model and adjust itself accordingly.
5.6 E-Commerce
The social transparency and design framework that support trust in the judgment of AI-based systems used in e-commerce have been studied by the authors. The pro­motion of social transparency calls for a deeper comprehension of articial intelligence- based systems. XAI transparency can be used as a helpful marketing strategy, even though its long-term effects have not been studied. A less visible algorithm may also exacerbate privacy issues because analytics for Internet adver­tising leverage personal data [12]. An explainable AI-based solution that combines text and augmented reality with online shopping is better. Customers are more trust­worthy, which makes for a better online shopping experience.
46
S. Mohanthy et al.
5.7 Human Resource Management
Many factors affect how willing employees are to accept decisions made by arti­cial intelligence in human resource management. Many employees think that decision- making can be skewed, deceptive, and an infringement on privacy. As a result, adopting predictions based on AI may be mentally taxing. Decision-making can be better understood by closing the knowledge gap and improving transparency and interpretability. Collaboration with human users throughout the design phase can also raise the likelihood that the system will be adopted and improve the user’s attitude towards the system [13]. The algorithmic hiring method is gaining popular­ity. It’s becoming more and more common to use an algorithm for hiring. Explaining the decision-making process, describing the candidate’s evaluation results, and demonstrating comparable recruitments within the company are all examples of the ability criteria for recruiters. The recruiters may be able to identify potential bias in the decision-making process by using data from a similar prior recruitment. Also, if different recruiters are utilizing the system and switching shifts, it is a good idea to present a summary of prior work each time they log in to the system.
5.8 Digital Assistants
According to earlier research, users are more likely to trust virtual assistants when they are more engaged and human-like. Users nd encouragement and attraction in verbal comments, gestures, and voices, particularly those that refer to phonemes. An XAI system must also provide linguistic justications for end users. As a result, an interactive agent with a balanced blend of explicable AI techniques and a suitable linguistic representation can increase the trustworthiness and user-centeredness of a system.
5.9 E-Governance
In order to determine how fair machine-learning algorithms are seen by users and whether these algorithms require explanations, empirical evaluations of a criminal justice use case were conducted. The system should explain how the algorithm works, the factors that inuence decision-making, and the availability of contextual data in order to boost the system’s understandability, credibility, and trustworthi­ness. Similar to how examinations into the use of algorithms in immigration ser­vices show that not all judgments must be made using algorithms, even though algorithms can aid in decision-making [14]. One investigation also found that the white-box strategy, which uses explainable AI, can result in improved judgment. As a result, crucial decisions made by e-governance require human involvement.
Explainable AI Methods andApplications
47
5.10 Social Networking
According to research in the social networking eld, users want both “why” and “why not” justications for particular system actions. Developers can thus instantly deliver user log data, mental model-related data, and contextual data [15]. In addi­tion, a successful explainable AI system needs human user input during the design phase via a specic communication channel.
6 Conclusion
Humans are nding it more and more difcult to understand and follow the steps taken by the algorithm as AI develops. The whole computation is reduced to a “black box,” which is difcult to understand. The data is used to generate these black-box models. Furthermore, nobody can explain what exactly is going on inside of them, not even the engineers or data scientists who developed the algorithm, let alone how the AI algorithm came to a certain conclusion. Thanks to a set of methods and techniques known as explainable articial intelligence (XAI), the output and results of machine learning algorithms may now be comprehended and trusted by human users. In terms of explainable AI, an AI model, its projected outcomes, and any biases are all described. It helps dene model accuracy, fairness, and transpar­ency and results in AI-supported decision-making. A company must rst build trust and condence before implementing AI models. With the help of AI’s explaining ability, a corporation can adopt a responsible approach to AI development. Several strategies are discussed to get a head start on this subject, including intrinsic and post-hoc explanations of ability. For each methodology, conceptual and in-depth justications with examples are also covered. We have offered XAI as a tool to be applied to various types of data, such as images, text, and tabular data, after offering a conceptual knowledge of XAI methodologies.
In addition to the unconscious biases, we previously highlighted, XAI also faces the following difculties: transparency, fairness, safety, and complexity. More faults for an XAI algorithm are a concern; however, it is simpler to nd errors in an XAI method. AI activities are frequently so intricate that “extracting” them from the opaque “black box” might be difcult. Utilizing continuous model evaluation, a company can compare model predictions, quantify model risk, and enhance model performance.
References
1. Jagatheesaperumal SK, Pham Q-V, Ruby R, Yang Z, Xu C, Zhang Z (2022) Explainable AI over the internet of things (IoT): overview, state-of-the-art and future directions. arXiv:2211.01036v2 [cs.AI]
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2. Arikan ZB. An introduction to explainable AI. https://www.mobiquity.com/insights/
an- introduction- to- explainable- artical- intelligence
3. Vilone G, Longo L (2020) Explainable articial intelligence: a systematic review. arXiv:2006.00093v4 [cs.AI]
4. Netapp. Mike McNamara. netapp.com/blog/explainable- ai/#sub2- 1
5. Zhang Y, Weng Y, Lund J (2022) Applications of explainable articial intelligence in diagnosis and surgery. Diagnostics 12:237. https://doi.org/10.3390/diagnostics12020237
6. Durmus M. Inside the black box: 5 methods for XAI. https://www.aisoma.
de/5- methods- for- explainable- ai- xai/
7. Yang W, Hoi S, Rose D. Making explainable AI easy for any data, any models, any tasks.
https://blog.salesforceairesearch.com/omnixai/
8. Srinivasu PN, Sandhya N, Jhaveri RH, Raut R (2022) From blackbox to explainable AI in healthcare: existing tools and case studies. Mobile Inform Syst 2022:8167821. https://doi.
org/10.1155/2022/8167821
9. Bahalul Haque AKM, Najmul Islam AKM, Mikale P (2023) Explainable articial intelligence (XAI) from a user perspective: a synthesis of prior literature and problematizing avenues for future research. Technol Forecast Soc Change 186(Part A):122120. https://doi.org/10.1016/j.
techfore.2022.122120
10. Ngo T, Kunkel J, Ziegler JE.Exploring mental models for transparent and controllable recom­mender systems: a qualitative study. https://doi.org/10.1145/3340631.3394841
11. Cheng H, Wang R, Zhang Z, O’Connell F, Gray T, Harper FM, Zhu H.Explaining decision­making algorithms through UI: strategies to help non-expert stakeholders. https://doi.
org/10.1145/3290605.3300789
12. Ehsan U, Liao QV, Muller M, Weisz JD.Expanding explainability: towards social transpar­ency in AI systems. https://doi.org/10.1145/3411764.3445188
13. Binns RD, Van-Kleek MG, Veale M, Lyngs U, Zhao J, Shadbolt NR. ‘It’s reducing a human being to a percentage’: perceptions of justice in algorithmic decisions. https://doi.
org/10.1145/3173574.3173951
14. Janssen M, Hartog M, Kuk G (2020) Will algorithms blind people? The effect of explainable AI and decision-makers’ experience on AI-supported decision-making in government. Soc Sci Comput Rev 40(1):089443932098011. https://doi.org/10.1177/0894439320980118
15. Jiang H, Senge E (2021) On two XAI cultures: a case study of non-technical explanations in deployed AI system. arXiv:2112.01016v1 [cs.HC]
S. Mohanthy et al.
Unveil theBlack-Box Model forHealthcare
Explainable AI
RajanikanthAluvalu, V.SowmyaDevi, Ch.NiranjanKumar, NittuGoutham, andK.Nikitha
Abstract Deep neural networks are nowadays widely applied in mission-critical
systems such as medical devices, healthcare, medical imaging segmentation, self­driving cars, and military applications that have a direct inuence on human beings. Despite their massive success, many of these techniques are subject to the “black box” issue. To overcome the issues of the black-box method, eXplainable AI (XAI) is introduced. XAI can provide detailed information about the model and decision­making. In this chapter, we conduct a survey of the recent trends in medical, health­care, and other applications using XAI. We discuss the explanation from the user, then evaluation and measurement are conducted. A lot of attention is also paid to the use of different techniques of AI and XAI in the healthcare domain. We further dis­cuss the issues and challenges. Because of this, the research suggests that XAI in healthcare is still a novel topic that needs to be researched further in the future.
Keywords Articial intelligence · Black box · eXplainable AI · Healthcare
R. Aluvalu Symbiosis Institute of Technology, Hyderabad Campus, Hyderabad, Telangana, India
Symbiosis International (Deemed University), Pune, India
V. S. Devi (*) · C. N. Kumar Department of CSE, Sreenidhi Institute of Science and Technology, Hyderabad, Telangana, India
N. Goutham School of Computer and Systems Sciences, Jawaharlal Nehru University, New Delhi, India
K. Nikitha Department of Computer Science, MJPTBCWRDC for Women, Siddipet, Telangana, India
Ltd. 2024 R. Aluvalu et al. (eds.), Explainable AI in Health Informatics, Computational Intelligence Methods and Applications,
https://doi.org/10.1007/978-981-97-3705-5_3
49© The Author(s), under exclusive license to Springer Nature Singapore Pte
50
R. Aluvalu et al.
1 Introduction
The development of Articial Intelligence (AI) has advanced dramatically. AI includes Machine Learning (ML). ML’s primary function is to analyze data for recurring patterns or structures so that useful data models can be constructed. In the conventional sense, an algorithm is a limited set of rules for solving a problem. In contrast, modern data inputs and statistical analyses are trained with machine learn­ing [1] algorithms to generate a target value within a range. Articial intelligence has been crucial to the operations of many elds that have adapted to new informa­tion technology. Articial Intelligence (AI) stakeholders are increasingly demand­ing clarity as black-box Machine Learning (ML) models are utilized to make crucial assumptions in decision-making. Making and carrying out decisions that are not valid, acceptable, or easily interpretable in terms of their behavior [2] to pose a threat are discussed. In personalized medicine, for instance, professionals require much more information from the model than just a basic binary estimate to support their medical assessment [3]. People are typically unwilling to adopt procedures that are not easily understandable, tractable, or reliable. However, an improved comprehension of a model can lead to the modication of its defects. The aspect of understandability as a major design driver when developing an ML model can improve its implementation ability for the following reasons.
• Interpretability contributes to decision-making equality.
• Interpretability assists in the provision of reliability by helping individuals
develop adversarial instabilities that could change the predictive model.
• Interpretability can ensure that only signicant parameters are used to derive
the output.
To avoid restricting the efciency of today’s AI systems, eXplainable AI (XAI) suggests developing a set of machine learning approaches while keeping a high order of learning performance in both accuracy and precision, which create more explainable models and by which humans can understand the model effectively.
While the earliest AI systems could be understood readily, opaque decision­making techniques like Deep Neural Networks (DNNs) have become more preva­lent in recent years. As a result of a set of powerful learning algorithms and their enormous computational power, Deep Learning (DL) models like DNNs have dem­onstrated empirical success. The latter space has hundreds of levels and millions of parameters, which qualies DNNs as sophisticated black-box models [4]. Transparency, or the quest for a clear knowledge of a model’s operating process, is the antithesis of black box [5].
The term “black box machine learning” is used to characterize ML models that provide you with a result or a decision without explaining or revealing their reason­ing behind the decision. Both the internal processes used and the myriad of criteria considered are mysteries. That is to say, there is a lack of clarity in the way this technology operates. A black-box paradigm indicates that no one, not even the
Healthcare
Domain Agnostic
Unveil theBlack-Box Model forHealthcare eXplainable AI
51
administrators and programmers of the computer or algorithm, is aware of or com­prehends how the output was produced.
The adoption of XAI techniques faces some difculties. The XAI approaches’ explanations ought to be useful for the end users, who may be either regular people or physicians with specialized medical knowledge [6]. It is possible to create suit­able user interfaces for the presentation of explanations [7]. Model-agnostic XAI approaches continue to face difculties relating to higher computational costs and assumption-based operations [8].
1.1 Motivation
AI encompasses several methods under its roof, such as ML, to predict outcomes. ML eventually achieves the objective of producing correct results by training the model. A cyberattack on the National Highway Authorities of India (NHAI) core server occurred in 2020 as a result of an inadequate cyber security system [9]. In such cases, eXplainable AI (XAI) can provide a proper explanation and identify efforts that should be made to avert future cyberattacks.
The chapter’s primary goal is to investigate the challenges and limitations of existing AI models in healthcare and the potential risks associated with the “black box”. Figure1 shows how research is spread out in different types of domains. In this context, it becomes evident that the healthcare domain gains more atten­tion in XAI.
Fig. 1 XAI in various domains
16%
49%
21%
7%
Industry
Transportation
Finance
Miscellaneous
52
R. Aluvalu et al.
1.2 Scope ofthePaper
Because the amount of structured and unstructured data is continuously growing, AI is an enabling paradigm revolutionizing the healthcare domain, and sophisticated wearable devices, such as tness devices, etc., may forecast the emergence of health issues in users by recording and interpreting their health data. XAI is the study that focuses on developing methods to explain the underlying assumptions and decision­making processes of AI systems. By studying black-box models and their decision­making processes, XAI helps healthcare providers verify the accuracy of the results produced by machine learning algorithms, which is critical in the medical industry. This explains the importance of AI in various healthcare domains and other elds.
The remaining chapter is ordered as follows: In Sect. 2, we will discuss the importance of healthcare in eXplainable AI.In Sect. 3, we will discuss the various work done in healthcare using XAI.In Sects. 4 and 5, we will discuss the various applications of eXplainable AI in different domains and its challenges, and nally, a conclusion is given in Sect. 6.
2 Deep Learning: AMysterious Black Box
Experts earn respect because of the results they generate and the rationales they provide for their choices. There is a signicant body of thought supporting the notion that specialists in a given eld should be able to defend their decisions by drawing on their extensive understanding of the relevant causal linkages.
There is a statement that goes something like, “By justications, we mean expla­nations that tell why an expert system’s behaviors are reasonable in terms of the principles of the domain—the thinking behind the system.”
When designing a deep learning system, developers don’t include a model that depicts how they think the problem’s causes interact with one another. Predictions made by deep learning algorithms, which may be trained on millions of data points, can be quite precise.
Nonetheless, deep learning algorithms can be mysterious despite their precision. The models used for classication by these systems can be incomprehensible to humans, even though their designers comprehend their architecture and the method by which the models are generated. The connections between input data and the nal classication may be indirect and fragile, even when methods are employed to determine the features for which a model assigns considerable weight when evaluat­ing a given example. Subtle changes to seemingly unrelated data can have a pro­found impact on how attributes are weighted. Furthermore, models might be built differently depending on the original conditions.
When it comes to medicine, our ability to precisely predict causal relationships in a higher percentage of the systems in which we engage typically lags behind our experience-based ability to get things done around the world by using particular
Unveil theBlack-Box Model forHealthcare eXplainable AI
relationships. Considerable portions of current medical practice are reective of a synthesis of empirical results and an ingrained clinical culture.
In domains where our understanding is lacking, we may use a recommendation system to prefer interpretability over prediction and diagnosis. When doctors give such recommendations to their patients, it can hurt them in the form of misdiag­noses or lead to unwanted testing. They may also encourage using ML systems for which they are not suitable, thinking that they are highly predictive models, but they are shown to be insufcient [10]. Table1 describes the literature on XAI applica­tions in different domains.
53
2.1 Deep Learning intheReal World
Even though DL techniques have shown promise in the medical area, interpretabil­ity has remained one of the largest problems. Deep learning techniques are fre­quently described as “black boxes” by academics because it is difcult to understand how and why the suggested algorithms may perform so effectively. It is still difcult to persuade healthcare professionals to follow exactly what the machines advise humans to do because all of the medical outcomes generated are strongly tied to issues of life and death.
In the near future, with the difculties and scarcity of different types of data, humans will still be the most important part of the healthcare industry, which includes expert knowledge in existing deep learning techniques. So, adding the priceless knowledge of experts to the deep learning techniques that are already in place might not only lead to better results but also teach the machines to learn in a more precise way. Table2 gives the deep learning in healthcare applications.
2.2 Datasets intheHealthcare Domain
Datasets are the primary input resources for DL algorithms. Based on the applica­tion, it can be used for classication, prediction, and recommendation. In health­care, clinical decisions can be complex and challenging. DL algorithms can be useful tools for decision-making processes, but the attributes that are given as input to the algorithms must be quantiable and measurable [37].
DL techniques can also be applied to the Electronic Health Record (EHR), which mainly performs data extraction like possible diseases and proposed treatments with respect to time events, like this month, etc. Table3 provides some of the most popu­lar datasets related to images and patient records.
54
Existing state-of-the-art works
Table 1
Ref. no. and year Aim Used method Observations
[11],
Utilizes chest X-ray
2020
images for COVID-19 eXplainable prediction
[12],
In order to detect the
2020
presence of COVID- 19 using CT and chest X-ray images, a DNN has been developed
[13],
AI approaches are
2021
being used to study human-computer interaction with XAI in healthcare
[14],
In 5G-enabled IoT,
2021
COVID-19 diagnosis using CNN and SVM
[15],
Real-time heart
2021
monitoring for COVID-19 patients using deep learning and 5G
[16],
Gives literature on
2021
XAI in AI and DL domains
[17],
Describes Healthcare
2022
5.0’s focus on individualized care made possible by articial intelligence (AI) and the Internet of Things (IoT)
XAI, DNN, and class activation mapping
DNN, LIME An accuracy of 95% for the chest and
AI, HCI, and EXAI The state-of-the-art literature is used to
IoT, DWS-CNN, and Gaussian ltering
5G, DL, CNN, and LSTM
Prototype-based models, Surrogate models
AI and non-AI approaches, IoT
The suggested model performs better than conventional methods for classifying COVID-19, with PPV and recall metrics of 96.12% and 94.3%, respectively. Does not take into account external circumstances or symptoms while calculating COVID-19 potential values
X-ray is reported. EXAI metrics are not taken into account
talk about HCI, AI, and EXAI.The survey also talks about how EXAI is used in healthcare and what problems have come up in past literature surveys. Does not talk about EXAI’s solution taxonomy in healthcare for use-case scenarios
Data gathering, preprocessing with a Gaussian lter, feature extraction, and classication are all used in the proposed depth-wise separable-CNN model for detecting different classes of COVID-19 lacks possible solutions and fails to describe the communication model for the Internet of Things (IoT) that benets from 5G
Proposed IoT wearables for heart monitoring, and the data is processed using DNN.Does not look into how DNN, LSTM, and CNN can be combined to make predictions and generalizations more accurate
Proposed an analysis of XAI and provided solutions for the challenges. But not concentrated on healthcare applications
Contextualize healthcare IoT to promote clinical personalization, explain AI and non-AI methods, and provide a use case. Lacks medical case evaluation and EXAI integration
R. Aluvalu et al.
(continued)