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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5628_Библиотеки_им_академика_М_И_Перельмана.pdf
104
Nano Physical Pharmaceutics of Liposome-Based System
3.4.3.2 Chemical stability of drug-loaded liposome
NPP of Liposomes in Drug Delivery
105
Tc Tc
T
c
3.4.4 Clearance and in vivo Circulation of Liposome
3.4.4.1 Influence of liposome size on clearance and in vivo
circulation
106
Nano Physical Pharmaceutics of Liposome-Based System
3.4.4.2 Inuence of liposome dose on clearance and in vivo
circulaon
in vivo
in vivo
NPP of Liposomes in Drug Delivery
107
t
t
3.4.4.3 Inuence of liposome charge on clearance and in vivo
circulaon
in vivo
3.4.4.4 Influence of phase transition temperature on
clearance and in vivo circulation
108
Nano Physical Pharmaceutics of Liposome-Based System
Tc is
plasma in vitro
in vivo
Tc
Tc
T
c
3.4.4.5 Inuence of steric stability of liposome on clearance
rate and in vivo circulaon
NPP of Liposomes in Drug Delivery
109
110
Nano Physical Pharmaceutics of Liposome-Based System
in vivo
in vivo
3.4.5 Targeting Ability of Liposome
NPP of Liposomes in Drug Delivery
111
112
Nano Physical Pharmaceutics of Liposome-Based System
3.4.6 Drug Release Behavior of Liposome
NPP of Liposomes in Drug Delivery
113
in vivo