Добавил:
kiopkiopkiop18@yandex.ru t.me/Prokururor I Вовсе не секретарь, но почту проверяю Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:
Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_3798_Библиотеки_им_академика_М_И_Перельмана.pdf
Скачиваний:
1
Добавлен:
15.09.2026
Размер:
17 Мб
Скачать
☆
37 Genital Lymphedema
309

Etiology

The etiology of genital lymphedema, except after surgery and irradiation, is usually postinflammatory and is caused by prior infection by microbes in the perineal and anal regions. The microbes entering the lymphatics are cocci in approximately 60% and bacilli in 40%. The most common are Staphylococcus epidermidis and
S. aureus, Enterococcus, and Micrococcus. In the bacilli population Pseudomonas, Acinetobacter, Proteus, Enterococcus, Enterobacter, and Corynebacteria dominate.
Why only a few individuals develop infections is unclear; however, genetic pre­disposition is suspected.
The bacterial inflammatory process is followed by obliteration of afferent lym­phatics and fibrosis of the inguinal lymph nodes. This is why, in some cases of geni­tal lymphedema, lymphedema of the lower limbs also is seen.

Diagnosis

Diagnosis of genital lymphedema is based on:
(a) Physical examination revealing edema of the penis, scrotum or labia, disfigure-
ment of these parts, erythema and increased temperature, and, not infrequently, oozing of lymph from epidermal blisters.
(b) Lymphoscintigraphy with intradermal injection of T99-Nanocoll.
Differential diagnosis between postinflammatory, chyloperitoneum, and chylu-
ria with retroperitoneal backflow is based on:
(a) Histochemistry of oozing fluid: postinflammatory (presence of lymphocytes
and dendritic cells with few granulocytes); chyloperitoneum (high concentra­tion of lymphocytes and large macrophages).
(b) Chemistry of the fluid: presence of lipids determines intestinal origin of fluid
(chyloperitoneum).
(c) Lymphoscintigraphy: postinflammatory (lack of absorption and flow of radio-
isotope from the skin of the swollen parts toward the inguinal area, chyloperito­neum (isotope accumulates in dilated lymphatics spreading toward the thigh, pelvis, and retroperitoneal space, chyluria (dilated genital lymphatic with iso­tope flow to the retroperitoneum and kidney pelvis).

Clinical Course

Genital lymphedema develops relatively quickly because of the ready accumulation of tissue fluid in loose subcutaneous tissue. The main complications are: (a) rapid increase in mass to several kilograms, (b) lymph oozing from epidermal blisters, and (c) recurrent attacks of acute inflammation followed by chronic inflammation.
310 W.L. Olszewski

Treatment

Conservative: (a) in each case administration of either long-term penicillin 1,200,000 IU, intramurally, every 3 weeks or amoxicillin + clavulanic acid 2 g for 3 days orally every 3 weeks, cleansing with antibacterial soap, (b) manual massage of the swollen parts toward the groin, (c) wearing a suspensory to support and compress the scro­tum and penis.

Surgical

Postinflammatory: (a) removal of excess of skin and subcutaneous tissue after intra­operative elimination of the edema fluid from the penis, scrotum or labia toward the groin (Fig. 37.3) inguinal nodes, (c) in advanced cases, excision of the swollen skin and subcutis of the hypogastrium.
Chyloperitoneum: (a) laparotomy followed by (b) ligation and severing of retro­peritoneal lymphatic bundles along the iliac veins (Fig. 37.4), (c) in advanced and recurrent cases, excision of half the length of the small bowel that produces stagnant lymph leaking into the peritoneal cavity, (d) postoperative injection of bleomycin or 3% aetoxisclerol into scrotal or labial blisters. In advanced edema of the genitals, plastic surgery is performed in the postinflammatory group.
Chyluria with genital edema: (a) retroperitoneal laparoscopic or open denuda­tion of the kidney(s) and ligation of the dilated lymphatics running toward kidney pelvis (Fig. 37.4).
Technical hints: (a) scrotum: create a small anterior flap, leave as little skin as pos­sible just to cover the denuded testes, remove afferent lymphatics with swollen tissues in the hypogastrium, use diathermy and avoid ligatures (foci of future abscesses),
1-8
, (b) excision of fibrotic afferent lymphatics running toward the
Fig. 37.3 Postoperative view of a reduced scrotum and exposure of the hidden penis. Small scrotal anterior flap. Circumcision of the penis. Elongation of the penis will require further plastic surgery
37 Genital Lymphedema
Fig. 37.4 Lymphoscintigram depicting iliac lymphatic bundles running along large pelvic veins. Lines crossing the bundles indicate where ligation and transection should take place. Arrows show sites of retroperitoneal lymphatics draining the kidneys and extravasated isotope in cases of chyluria
311
retain the urinary catheter until the wound has healed up, (b) penis: perform circumci­sion followed by longitudinal incision on the dorsum or lateral aspects and remove excess tissue, leave some more skin to allow future erection. Secondary plastic sur­gery of the penis is usually necessary. The application of a split-thickness skin graft involving the penile shaft promotes adequate skin coverage, with a penile girth com­patible with sexual intercourse and little alteration in sensitivity. The zigzag suture of the graft on the ventral surface of the penis is aimed at avoiding scar contracture and subsequent ventral curvature of the penis. (c) Labia: remove as much tissue as possi­ble, recurrence of edema is frequent.
Postoperative therapy: (a) antibiotics: long-term penicillin (bicillin) 1,200,000 IU, intramurally every seventh day for 1–2 months, followed by one injection every 3 weeks for 1 year or alternatively amoxicillin + clavulanic acid at a dosage of 1 g daily for 3 months and then 2 g for 3 days every 3 weeks, (b) manual massage of the remnant swollen tissues.
Postoperative complications: (a) slow recurrence of edema, (b) recurrence of local inflammatory episodes, (c) recurrence of lymph oozing, requiring injection of sclerosants, and (d) hidden penis requiring elongation.

References

1. Dandapat MC, Mohapatro SK, Patro SK. Elephantiasis of the penis and scrotum. A review of
350 cases. Am J Surg. 1985;149:686-690.
2. McDougal WS. Lymphedema of the external genitalia. J Urol. 2003;170:711-716.
312 W.L. Olszewski
3. Modolin M, Mitre AI, da Silva JC, et al. Surgical treatment of lymphedema of the penis and
scrotum. Clinics (Sao Paulo). 2006;61:289-294.
4. Halperin TJ, Slavin SA, Olumi AF, Borud LJ. Surgical management of scrotal lymphedema
using local flaps. Ann Plast Surg. 2007;59:67-72.
5. Milanović R, Stanec S, Stanec Z, Zic R, Rudman F, Kopljar M. Lymphedema of the penis and
scrotum: surgical treatment and reconstruction. Acta Med Croat. 2007;61:211-213.
6. Garaffa G, Christopher N, Ralph DJ. The management of genital lymphedema. BJU Int.
2008;102:480-484.
7. Zacharakis E, Dudderidge T, Zacharakis E, Ioannidis E. Surgical repair of idiopathic scrotal
elephantiasis. South Med J. 2008;101:208-210.
8. Zugor V, Horch RE, Labanaris AP, Schreiber M, Schott GE. Penoscrotal elephantiasis: diag-
nostics and treatment options. Urologe A. 2008;47:472-476.
Chapter 38
Psychological Aspect: Compliance and Quality of Life
Cheryl L. Morgan
An estimated 99 million Americans live with chronic illness. The majority have not received effective treatment or optimal disease control.1 Health services research indicates that it is the design of the care system, not the specialty of the physician or allied health professional, that is the primary determinant of the quality of chronic care.2 Collaborative relationships with health care providers can help patients and families acquire effective medical, preventive, and health maintenance interven­tions.3 Moreover, collaborative care between health care providers can help improve outcomes and adherence to self-care programs. Patient adjustment to requirements to maintain their health is improved when reinforced by each professional involved in his or her plan of care. They even develop adaptations to improve their own abili­ties to maintain the results achieved by treatment when accountability is empha­sized by all members of their health care team.
The term compliance has mostly been superseded by the term adherence, a simi­lar concept, but one that has fewer negative connotations regarding the physician and patient relationship. Use of the term compliance has been strongly criticized because it was thought to convey a negative image of the relationship between patient and physician, in which the role of the physician was to issue the instructions and the patient’s role was to follow the doctor’s orders. Noncompliance, therefore, could be interpreted as patient incompetence with being unable to follow instruc­tions or as deliberate, self-sabotaging behavior.
The term adherence was introduced in an attempt to recognize a patient’s right to choose, to participate actively in his or her plan of care, and to remove the concept of blame. It recognizes the need for patients, physicians, and allied health care pro­fessionals to work together to reach agreement and improve outcomes.6 How we deal with this presents a major challenge for medicine, particularly in the manage­ment of chronic illnesses, such as lymphedema.
4
5
C.L. Morgan Department of Rehabilitation Medicine, Therapy Concepts Inc., Leawood, KS, USA
B.-B. Lee et al. (eds.), Lymphedema, DOI 10.1007/978-0-85729-567-5_38, © Springer-Verlag London Limited 2011
313
314 C.L. Morgan
The issue of one’s quality of life for those living with chronic illness is important to consider when evaluating a patient’s ability to manage lymphedema during treat­ment and thereafter. When possible, a comprehensive assessment would include not only a physical evaluation, but also would consider the psychological, emotional, and social concerns the patient may encounter.
Lymphedema patients are living an interrupted life replete with stages of emo­tional experiences and adaptive behavioral responses that correspond or collide with the individual’s unique coping mechanisms. These emotional stages can range from feeling a violation of physical intactness to loss of autonomy. In some cases, lym­phedema patients are dually threatened with death if they are suffering with cancer or other comorbidities complicating their recovery. Loss of activity, social isolation, and fear of stigmatization can threaten social identity and self worth.
7
Adaptive behavioral responses can include resignation, disengagement or a refusal to help themselves. Some patients present with denial, avoidance, repressed anger or depression. These are largely unconscious responses that stop imagination or emotions from threatening a patient’s sense of self. All represent defense mecha­nisms that can impair results of treatment if not addressed or are dismissed as noncompliance.
8
Conscious coping mechanisms act as reality adjustors for the real world and are generally considered a more constructive overt behavior.9 Stress research models have identified three fundamental types of conscious coping. Information focused
coping is demonstrated by patients who seek instruments of emotional help. Emotional focused coping is observed in patients who vent emotions, denial, escape avoidance or acceptance of responsibility. Patients who utilize problem-oriented coping mechanisms will exercise active coping techniques, plan, and identify prac-
tical approaches to address stress.
10
Consistent knowledge base and training of physicians and allied health profes­sionals, paired with standardized information or resources, provide patients with confidence in the treatment approach and its demands. This is particularly important with protocols as demanding of time and resources as lymphedema management. Reliable direction helps prevents patients from pursuing unproven and often costly treatments. Obtaining incorrect or contradictory information promotes frustration and distrust and can lead to patients rejecting medical attention or non-adherence.
11
Communication of expectations of therapeutic intervention involving family or caregivers in the selection of means of accountability fosters adherence with even strict protocols. Establishing reasonable outcomes and providing simple methods of measuring progress encourage patients and improve consistency with self care.12 Instructions should be practical and individualized. Successful treatment is probable when a continuum of support and training is available to patients and active and sustained follow-up is available.
13
Access to resources, treatment, literature, and supplies continues to encumber patients with lymphedema. Physician-directed care that is provided by experienced therapists, will enhance a patient’s experience and provide superior results.
2
Support systems that provide additional resources are an important part of a successful pro­gram.4 Without standardized educational requirements for health professionals or
38 Psychological Aspect: Compliance and Quality of Life
315
treatment protocols, lymphedema patients are often left on their own to learn about their condition and find treatment they can afford to pursue.
Improved communication between physicians and allied health professionals is increasing as awareness of the options for these patients increases. Once consensus on diagnosis, staging, and treatment of lymphedema can be reached, measureable outcomes can support the standardization of professional medical education, and improve reimbursement for treatment and supplies.
14
Effective medical management of lymphedema is more likely to occur when col­laborative care is consistently provided, and takes into consideration the patient’s indi­vidual coping skills and variables that affect their quality of life and access to optimal treatment. Respecting each patient’s autonomy, drawing out any concerns or ambiva­lence about pursuing treatment, and allowing the patient to develop and/or own the treatment plan greatly improve the odds of achieving positive clinical outcomes.15 The growing population of chronically ill patients, such as patients with lymphedema, will require the development of successful systems and collaborative care.
16

References

1. Rothman A, Wagner E, et al. Chronic illness management: What is the role of primary care?
Ann Intern Med. 2003;138(3):256-261.
2. Casalino LP. Disease management and organization of physician practice. JAMA. 2005;
293(4):485-488.
3. Von Korff M, Gruman J, et al. Collaborative management of chronic illness. Ann Intern Med.
1997;127(12):1097-1102.
4. Cretin S, Shortell SM, Keeler EB. An evaluation of collaborative interventions to improve
chronic illness care: framework and study design. Eval Rev. 2004;28(1):28-51.
5. Haynes RB, Sackett DL, Taylor DW. Compliance in Healthcare. Baltimore: Johns’ Hopkins
University Press; 1979.
6. World Health Organization. Adherence to Long-Term Therapies: Evidence in Action. Geneva:
World Health Organization; 2003.
7. Redman BK. The ethics of self management for chronic illness. Nurs Ethics. 2005;12(4):
360-369.
8. Cramer P. The Development of Defence Mechanisms: Theory, Research, and Assessment. New
York: Springer; 1991.
9. Faller H, Bülzebruck H, Drings P, Lang H. Coping, distress, and survival among patients with
lung cancer. Arch Gen Psychiatry. 1999;56(8):756-762.
10. Lazarus RS, Folkman S. Stress, Appraisal, and Coping. New York: Springer; 1984.
11. Stille CJ, Jerant A, et al. Coordinating care across diseases, settings and clinicians. Ann Intern
Med. 2005;142(8):700-708.
12. Zatzick D, Roy-Byrne P, et al. A randomized effectiveness trial of stepped collaborative care
for acutely injured trauma survivors. Arch Gen Psychiatry. 2004;61(5):498-506.
13. Russell E, Wagner EH, Schaefer J, et al. Development and validation of patient assessment of
chronic illness care (PACIC). Med Care. 2005;43(5):436-444.
14. Tretbar LL, Lee BB, Morgan CL, et al. Lymphedema; Diagnosis and Treatment. New York:
Springer; 2007.
15. Butterworth S. Influencing patient adherence to treatment guidelines. J Manag Care Pharm.
2008;14(suppl S-b):S21-S25.
16. Wagner EH. Chronic disease care. BMJ. 2004;328(7433):177-178.
Part IX
Surgical Treatment:
Reconstructive Surgery