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References 181
https://t.me/med1917
50 Haikal L, Ferraz Dos Santos B, Vu DD, Braniste M, Dabbagh B. Biodentine pulpotomies on
permanent traumatized teeth with complicated crown fractures. J Endod. 2020;46:1204–9.
51 Yang YT, Xia B, Xu Z, Dou G, Lei Y, Yong W. The effect of partial pulpotomy with iRoot BP Plus in
traumatized immature permanent teeth: a randomized prospective controlled trial. Dent
Traumatol. 2020;36:518–25.
52 Bissinger R, Müller DD, Reymus M, Khazaei Y, Hickel R, Bücher K, etal. Treatment outcomes
after uncomplicated and complicated crown fractures in permanent teeth. Clin Oral Investig.
2021;25:133–43.
53 Wu J, Li X, Xu L, Tang Z, Zhao J, Xiang Y, etal. Radiographic evaluation of immature traumatized
incisors following different endodontic treatments. Dent Traumatol. 2021;37:330–7.
54 Viduskalne I, Care R. Analysis of the crown fractures and factors affecting pulp survival due to
dental trauma. Stomatologija. 2010;12:109–15.
55 Bücher K, Neumann C, Thiering E, Hickel R, Kühnisch J. Complications and survival rates of teeth
after dental trauma over a 5- year period. Clin Oral Investig. 2013;17:1311–8.
56 Fuks AB, Cosack A, Klein H, Eidelman E. Partial pulpotomy as a treatment alternative for exposed
pulps in crown- fractured permanent incisors. Endod Dent Traumatol. 1987;3:100–2.
57 Bogen G, Dammaschke T, Chandler N. Vital pulp therapy. In: Berman LH, Hargreaves KM (eds.)
Cohen’s Pathways of the Pulp, 12th Ed., Elsevier, St Louis, Missouri, USA, 2020, 902–38.
58 Kang MK, Bogen G. Regenerative approaches in endodontic therapies of immature teeth. In:
Chugal N, Lin LM (eds.) Endodontic Prognosis. Clinical Guide for Optimal treatment outcome,
Springer, Switzerland, 2017, 65–86.
59 Cox CF, Bergenholtz G, Fitzgerald M, etal. Capping of the dental pulp mechanically exposed to
the oral microflora– a 5week observation of wound healing in the monkey. J Oral Path.
1982;11:327–39.
60 Andreasen JO, Andreasen FM, Mejàre I, Cvek M. Healing of 400intra- alveolar root fractures. 2.
Effect of treatment factors such as treatment delay, repositioning, splinting type and period and
antibiotics. Dental Traumatol. 2004;20:203–11.
61 Aguilar P, Linsuwanont P. Vital pulp therapy in vital permanent teeth with cariously exposed pulp:
a systematic review. J Endod. 2011;37:581–7.
62 Mohammadi Z, Dummer PMH. Properties and applications of calcium hydroxide in endodontics
and dental traumatology. Int Endod J. 2011;44:697–730.
63 Cox CF, Bergenholtz G, Heys DR, Syed SA, Fitzgerald M, Heys RJ. Pulp capping of dental pulp
mechanically exposed to oral microflora: a 1–2 year observation of wound healing in the monkey.
JOral Pathol. 1985;14:156–68.
64 Parirokh M, Torabinejad M, Dummer PMH. Mineral trioxide aggregate and other bioactive
endodontic cements: an updated overview. Part I. Vital pulp therapy. Int Endod J. 2018;51:177–205.
65 Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review. Part
III. Clinical applications, drawbacks, and mechanism of action. J Endod. 2010;36:400–13.
66 Kaur M, Singh H, Dhillon JS, Batra M, Saini M. MTA versus Biodentine: review of literature with a
comparative analysis. J Clin Diagn Res. 2017;11:ZG01–5.
67 Hirschman WR, Wheater MA, Bringas JS, Hoen MM. Cytotoxicity comparison of three current
direct pulp- capping agents with a new bioceramic root repair putty. J Endod. 2012;38:385–8.
68 Vu TT, Nguyen MT, Sangvanich P, Nguyen QN, Thunyakitpisal P. Acemannan used as an
implantable biomaterial for vital pulp therapy of immature permanent teeth induced continued
root formation. Pharmaceutics. 2020;12:644.
69 Matsuo T, Nakanishi T, Shimizu H, Ebisu S. A clinical study of direct pulp capping applied to
carious- exposed pulps. J Endod. 1996;22:551–6.
t.me/Dr_Mouayyad_AlbtousH

182
https://t.me/med1917
70 Cvek M, Cleaton- Jones PE, Austin JC, Andreasen JO. Pulp reactions to exposure after experimental
crown fractures or grinding in adult monkeys. J Endod. 1982;8:391–7.
71 Gungor HC. Management of crown- related fractures in children: an update review. Dent
Traumatol. 2014;30:88–99.
72 Shahmohammadi R, Sheikhnezami M, Moradi S, Jafarzadeh H, Azarpazhooh A. Treatment
outcomes of permanent immature teeth with crown fracture: a retrospective cohort study. J Endod.
2021;47:1715–23.
73 Robertson A. A retrospective evaluation of patients with uncomplicated crown fractures and
luxation injuries. Endod Dent Traumatol. 1998;14:245–56.
74 Jacobsen I, Kerekes K. Long- term prognosis of traumatized permanent anterior teeth showing
calcifying processes in the pulp cavity. Scand J Dent Res. 1977;85:588–98.
75 Belobrov I, Parashos P. Treatment of tooth discoloration after the use of white mineral trioxide
aggregate. J Endod. 2011;37:1017–20.
76 Laux M, Abbott PV, Pajarola G, Nair PN. Apical inflammatory root resorption: a correlative
radiographic and histological assessment. Int Endod J. 2000;33:483–93.
77 Bendo CB, Paiva SM, Varni JW, Vale MP. Oral health- related quality of life and traumatic dental
injuries in Brazilian adolescents. Community Dent Oral Epidemiol. 2014;42:216–23.
78 Damé- Teixeira N, Alves LS, Ardenghi TM, Susin C, Maltz M. Traumatic dental injury with
treatment needs negatively affects the quality of life of Brazilian schoolchildren. Int J Paediatr
Dent. 2013;23:266–73.
79 Silva- Oliveira F, Goursand D, Ferreira RC, Paiva PCP, Paiva HN, Ferreira EF, etal. Traumatic
dental injuries in Brazilian children and oral health- related quality of life. Dent Traumatol.
2018;34:28–35.
80 Antunes LA, Luiz RR, Leão AT, Maia LC. Initial assessment of responsiveness of the P- CPQ
(Brazilian Version) to describe the changes in quality of life after treatment for traumatic dental
injury. Dent Traumatol. 2012;28:256–62.
81 Nagendrababu V, Vinothkumar TS, Rossi- Fedele G, Doğramacı EJ, Duncan HF, Abbott PV, etal.
Dental patient- reported outcomes following traumatic dental injuries and treatment: a narrative
review. Dent Traumatol. 2023. https://doi.org/10.1111/edt.12827.
82 Santini AH. Intraoral comparison of calcium hydroxide (Calnex) alone and in combination with
Ledermix in first permanent mandibular molars using two direct inspection criteria. J Dent.
1985;13:52–9.
83 Calişkan MK. Success of pulpotomy in the management of hyperplastic pulpitis. Int Endod
J. 1993;26:142–8.
84 Calişkan MK. Pulpotomy of carious vital teeth with periapical involvement. Int Endod
J. 1995;28:172–6.
85 Da Rosa TA. A retrospective evaluation of pulpotomy as an alternative to extraction. Am J Dent.
2006;54:37–40.
86 Asgary S, Ehsani S. Permanent molar pulpotomy with a new endodontic cement: a case series.
JCons Dent. 2009;12:31–6.
87 Asgary S, Eghbal MJ, Ghoddusi J, Yazdani S. One- year results of vital pulp therapy in permanent
molars with irreversible pulpitis: an ongoing multicenter, randomized, non- inferiority clinical trial.
Clin Oral Investig. 2013;17:431–9.
88 Barngkgei IH, Haiboub ES, Alboni RS. Pulpotomy of symptomatic permanent teeth with carious
exposure using mineral trioxide aggregate. Iran Endod J. 2013;8:65–8.
89 Alqaderi HE, Al- Mutawa SA, Qudeimat MA. MTA pulpotomy as an alternative to root canal
treatment in children’s permanent teeth in a dental public health setting. J Dent. 2014;42:1390–5.
t.me/Dr_Mouayyad_AlbtousH

References 183
https://t.me/med1917
90 Asgary S, Eghbal MJ, Fazlyab M, Baghban AA, Ghoddusi J. Five- year results of vital pulp therapy
in permanent molars with irreversible pulpitis: a nontrial. Clin Oral Investig. 2015;19:335–41.
91 Asgary S, Eghbal MJ, Bagheban AA. Long- term outcomes of pulpotomy in permanent teeth with
irreversible pulpitis: a multi-
92 Taha NA, Ahmad MB, Ghanim A. Assessment of mineral trioxide aggregate pulpotomy in mature
permanent teeth with carious exposures. Int Endod J. 2017;50:117–25.
93 Galani M, Tewari S, Sangwan P, Mittal S, Kumar V, Duban J. Comparative evaluation of
postoperative pain and success rate after pulpotomy and root canal treatment in cariously
exposed mature permanent molars: a randomized controlled trail. J Endod. 2017;43:1953–62.
94 Taha NA, Abdulkhader SZ. Full pulpotomy with Biodentine in symptomatic young permanent
teeth with carious exposure. J Endod. 2018;44:932–7.
95 Taha NA, Abdulkhader SZ. Outcome of full pulpotomy using Biodentine in adult patients with
symptoms indicative of irreversible pulpitis. Int Endod J. 2018;51:819–28.
96 Asgary S, Hassanizadeb R, Torabzadeb H, Eghbal MJ. Treatment outcomes of 4 vital pulp
therapies in mature molars. J Endod. 2018;44:529–35.
97 Awawdeh L, Al- Qudah A, Hamouri H, Chakra RJ. Outcomes of vital pulp therapy using mineral
trioxide aggregate or Biodentine: a prospective randomized clinical trial. J Endod. 2018;44:
1603–9.
98 Ricucci D, Rôças IN, Alves FRF, Cabello PH, Siqueira JF Jr. Outcome of direct pulp capping using
calcium hydroxide: a long-
99 Lin LM, Ricucci D, Saoud TM, Sigurdsson A, Kahler B. Vital pulp therapy of mature permanent
teeth with irreversible pulpitis from the perspective of pulp biology. Aus Endod J. 2020;46:154–66.
100 Schwendicke F, Stolpe M. Direct pulp capping after a carious exposure versus root canal
treatment: a cost-
101 Li Y, Sui B, Dahl C, etal. Pulpotomy for carious pulp exposures in permanent teeth: a systematic
review and meta- analysis. J Dent. 2019;84:1–8.
102 Cushley S, Duncan HF, Lappin MJ, etal. Pulpotomy for mature carious teeth with symptoms of
irreversible pulpitis: a systematic review. J Dent. 2019;88:103158.
103 Mjör IA, Tronstad L. The healing of experimentally induced pulpitis. Oral Surg Oral Med Oral
Pathol. 1974;38:115–21.
104 Warfvinge J, Bergenholtz G. Healing capacity of human and monkey dental pulps following
experimentally-
105 Chueh LH, Chiang CP. Histology of irreversible pulpitis premolars treated with mineral trioxide
aggregate pulpotomy. Oper Dent. 2010;35:370–4.
106 Dominguez MS, Witherspoon DE, Gutmann JL, Opperman LA. Histologic and scanning electron
microscopic assessment of various vital pulp- therapy materials. J Endod. 2003;29:324–33.
107 Chacko V, Kurikose S. Human pulp response to mineral trioxide aggregate (MTA): a histologic
study. J Clin Pediat Dent. 2006;30:203–9.
108 Cvek M, Lundberg M. Histological appearance of pulps after exposure by a crown fracture, partial
pulpotomy and clinical diagnosis of healing. J Endod. 1983;98:8–11.
109 Cvek M, Granath L, Cleaton- Jones P, Austin J. Hard tissue barrier formation in pulpotomized
monkey teeth capped with cyanoacrylate or calcium hydroxide for 10 and 60minutes. J Dent Res.
1987;66:1166–74.
110 Robertson A, Andreasen FM, Andresen JO, Noren JG. Long- term prognosis of crown- fractured
permanent incisors. The effect of stage of root development and associated luxation injury.
IntJPaediatr Dent. 2000;10:191–9.
effectiveness analysis. J Endod. 2014;40:1764–70.
induced pulpitis. Endod Dent Traumatol. 1986;2:256–62.
center randomized controlled trial. Am J Dent. 2017;30:151–5.
term retrospective study. J Endod. 2023;49:45–54.
inferiority multicenter randomized clinical
t.me/Dr_Mouayyad_AlbtousH

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https://t.me/med1917
111 Garcia- Godoy F, Murray P. Systemic evaluation of various haemostatic agents following local
application prior to direct pulp capping. Braz Oral Sci. 2005;4:791–7.
112 Yilmaz Y, Guler C, Sahin H, Eyuboglu O. Evaluation of tooth- fragment reattachment: a clinical
and laboratory study. Dent Traumatol. 2010;26:308–14.
113 Garcia FCP, Proubel DLN, Almeida JCF, Dias Ribeiro AP, Toledo IP, Poi WR, etal. Tooth fragment
reattachment techniques– a systematic review. Dent Traumatol. 2018;34:135–43.
114 Khandelwal P, Srinivasan S, Arul B, Natanasabapathy V. Fragment reattachment after
complicated crown2021;37:37–52.
115 Alonso V, Caserio M. A clinical study of direct composite full- coverage crowns: long- term results.
Oper Dent. 2012;37:432–41.
root fractures of anterior teeth: a systematic review. Dent Traumatol.
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9
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Regenerative Endodontics
Matthias Widbiller 1 and Kerstin M. Galler
1
Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany
2
Department of Operative Dentistry and Periodontology, Friedrich- Alexander- University, Erlangen, Germany
2
Introduction
Pulp necrosis can be the result of deep caries, trauma or dental anomalies. As a consequence,
bacterial colonization of the root canal triggers apical periodontitis, which may be initially asymptomatic (asymptomatic apical periodontitis) or associated with pain or other clinical signs of
infection (symptomatic apical periodontitis). Classically, the goal of endodontic treatment is to
cure apical periodontitis and resolve the associated clinical symptoms by thorough disinfection
and filling of the root canal system.
In this context, root canal treatment of immature teeth poses a particular challenge for clinicians
because these teeth typically have short roots with thin dentine walls and a wide apical foramen
(Figure9.1a,b). Various treatment options are available, such as apexification with repeated intracanal dressings with calcium hydroxide or the placement of an apical barrier with a hydraulic
calcium silicate cement (HCSC). Traditional apexification involves multiple visits and alternating
intracanal applications of calcium hydroxide to induce the formation of a calcified barrier at the
root apex(1). Once this barrier is formed, the canal can be obturated with guttatooth can be restored. However, several disadvantages come with this treatment that make it no
longer the preferred option. Multiple visits are required, therefore the total treatment time is long,
and the prolonged contact of root dentine with calcium hydroxide in combination with the lack of
a definitive restoration increases the risk of tooth fracture(2, 3). Given these disadvantages, the
current recommendation for immature teeth is to place an apical plug with HCSC and seal the rest
of the canal with gutta- percha (Figure9.1b). This allows the treatment to be completed quickly and
with few appointments (4). However, this will still leave short roots with thin root walls, which
means an increased risk of fracture(5, 6).
The vision of endodontic regeneration is based on the restoration of the dentine–pulp complex,
where a regenerated pulp tissue will take over all the biological functions of the original pulp, leading to the completion of physiological tooth development.
percha and the
185
Vital Pulp Treatment, First Edition. Editedby Henry F.Duncan andIkhlas A. El-Karim.
© 2024John Wiley & Sons Ltd. Published 2024 by John Wiley & Sons Ltd.
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Regenerative Endodontics186
(a) (b) (c)
(a) (b)
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Figure9.1 (a) The apex of a juvenile tooth without completed root growth is very wide, depending on the
stage of development, and has thinly tapering root walls. (b) Root growth is only complete in the first few
years after the tooth erupts. When the pulp is lost, the root walls remain thin and the apical foramen wide.
(c) The conventional treatment for an immature tooth is to place an apical barrier with HCSC.
BiologicalandMechanicalGoalsofPulpRegeneration
From a biological perspective, regeneration is the process by which tissue is replaced or restored
both in form and function(7, 8). Irreversible inflammation or necrosis of the pulp causes clinical
and/or radiological symptoms and entails the removal of damaged tissues(9). With the loss of the
dental pulp, its various biological abilities are gone (Figure9.2).
One of the most important biological tasks of the dental pulp is root formation and the secretion
of dentine during and after tooth development. In addition, the pulp tissue can resist invading
microorganisms through mineral deposition and defend itself through specific and non- specific
Figure9.2 Histological representation of the dentine–pulp complex. (a) An odontoblast layer (arrowhead)
can be seen at the interface to the dentine (asterisk). (b) The core of the pulp shows a collagenous
extracellular matrix. Primarily fibroblasts and blood vessels with erythrocytes are visible (arrowheads) (H&E
staining; scale bars: 100 μm).
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(a)
(b)
Figure9.3 (a) Stages 1–5 of root
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development according to Cvek etal.(3).
Stages 1–4 describe tooth roots during
maturation, stage 5 the completed root
growth. Source: Adapted from Cvek etal.(3)/
John Wiley & Sons. (b) Stress distribution
pattern of an immature tooth during biting
shows concentration of mechanical force in
the fragile apical area. Source: Adapted from
Bucchi etal.(16). (c) A mature tooth with a
fully developed root can absorb more force
and distribute it better. Source: Adapted from
Bucchi etal.(16).
Stage 1
187
Stage 2 Stage 3 Stage 4 Stage 5
(c)
immune reactions(10, 11). An additional defence mechanism of the dentine–pulp complex is to
ensure an outward flow of dentinal fluid through the tubules(12). Consequently, loss of pulp
vitality may allow bacteria to migrate more easily through tubular dentine due to the lack of fluid
pressure, which is particularly evident in the significant bacterial invasion of dentine in non-
vital
teeth(13). Furthermore, the dental pulp is also a sensitive organ that can detect not only thermal,
mechanical or chemical stimuli, but also pathogenic irritants. The loss of the pulp inevitably leads
to the destruction of neuronal perception, which may play a role in persistent pain conditions and
functional changes of the trigeminal nerve(10, 14).
Besides all the biological implications of pulp loss, the long-
term survival of the tooth may be
compromised by the lack of mechanical strength due to possibly incomplete root maturation.(3,
15). The consequences are particularly severe for immature teeth in an early stage of root development (Figure9.3a). Because of their short roots and thin dentine walls, these teeth are predisposed
to fracture(3, 6). Pulp regeneration could facilitate the completion of root development, resulting
in increased mechanical strength (Figure9.3b) and, thus, long- term survival of affected teeth(16,
17). Due to the thin and fragile root walls of teeth with pulp necrosis in stages 1–3, endodontic
regeneration can offer decisive advantages as growth progresses (Figure9.3c). From stage 4, the
root has sufficient stability for both regenerative endodontic approaches and an apical barrier with
an HCSC to be suitable for treatment.
HistoricalDevelopmentofRegenerativeEndodontics
The field of regenerative endodontics has developed rapidly in recent years and has attracted considerable interest. New biology- based and minimally invasive concepts are increasingly finding
their way into everyday clinical practice and are changing the way of thinking in endodontics and
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Regenerative Endodontics188
(a) (b) (c)
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Figure9.4 (a) Preoperative radiograph of a lower second premolar with an open apex and apical
periodontitis. (b) Radiograph confirming the correct placement of MTA over the blood clot. (c) Follow-
radiograph after 18months showing continued root development and resolution of apical radiolucency.
Source: Banchs and Trope(20)/Reproduced with permission from Elsevier.
up
conservative dentistry. However, the idea of regenerating tissue inside the root canal system is
not new and dates back to the 1960s. In the paper ‘The role of blood clot in endodontic therapy’,
researcher Birger Nygaard- Østby studied provoked bleeding in the apical third of root canals
obturated with gutta-
percha in the coronal two- thirds (18). He observed partial or complete
replacement of the blood clot, mainly by fibrous connective tissue. These findings were forgotten,
and attempts to regenerate the pulp were abandoned for several decades before Iwaya etal. made
an interesting observation in 2001(19). In a case report, the authors described the treatment of a
lower premolar with incomplete root formation, chronic apical periodontitis and a sinus tract.
After disinfection and intracanal medication, the authors still demonstrated vital tissue inside the
root canal and applied calcium hydroxide only to the area of the canal entrance. Thirty months
after treatment, the completion of root formation was radiographically evident and the tooth
responded again to electrical pulp testing(19). A landmark clinical report was finally published in
2004 by Banchs and Trope, translating this observation into a potential treatment approach(20).
Similar to the case of Iwaya etal., the tooth involved was a lower premolar with an apical radiolucency and a sinus tract. The root canal was disinfected and treated with an intracanal medication.
After the signs of inflammation had subsided, bleeding into the canal was induced by mechanical
irritation of the vital apical tissue (Figure9.4). The resulting blood clot was covered with mineral
trioxide aggregate (MTA) at the level of the enamel- cementum junction. After 24months, the
osseous lesion had healed, root lengthening and thickening as well as apical closure were clearly
visible radiographically(20).
This publication was followed by numerous case reports, case series and clinical studies on this
biologically based treatment approach known today as revitalization(21, 22). Increasing scientific
evidence and experience with revitalization led to official recommendations from the major endodontic societies, the European Society of Endodontology (ESE) and the American Association of
Endodontists (AAE), on indications, case selection, procedural details, irrigation, materials and
recall(23, 24).
Revitalization
Revitalization has become a well- established treatment alternative to the apical plug after pulpectomy or pulp necrosis in immature teeth and is now an integral part of the endodontic treatment
spectrum. The aim is to create new tissue inside the root canal so that, if successful, the tooth root
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Revitalization 189
n
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Figure9.5 During revitalization, bleeding into
the root canal is induced by overA blood clot is formed and covered with a
collagen matrix. The root canal is sealed with a
bioactive HCSC and the cavity is sealed with an
adhesive restoration.
instrumentation.
Blood clot
Collagen
HCSC
Adhesive restoratio
can continue to grow and increase in length and thickness(24). Generally, the revitalization procedure is based on the induction of bleeding into the root canal, whereby mesenchymal stem cells
from the periapical tissue are flushed in (Figure9.5). A stable blood clot is formed, which acts as a
biological matrix and contains blood-
derived growth factors and multipotent stem cells(25). A key
to successful revitalization is optimal infection control and sufficient restoration of the tooth. This
allows for the development of a structured connective tissue inside the root canal, which is innervated, supplied by blood vessels and has the ability to form new hard tissue(25).
IndicationsandContraindications
Revitalization can now be considered a valid treatment option for immature teeth with pulp necrosis(24). Particularly in the early stages of root development (stages 1–3) (Figure9.3), when root
walls appear thin and fragile, revitalization can offer benefits by continuing root growth. With or
without the presence of apical periodontitis, this procedure can allow complete bony healing and
progression of root formation. However, revitalization of teeth is not advisable if a dental dam
cannot be applied or if extensive coronal hard substance loss would require insertion of an intracanal post. The indication should be given very cautiously, especially in immature replanted teeth
after avulsion, as autonomous revascularization is possible due to the wide- open apical foramen
and can be expected in about one- third of cases(26). Recommendations for revitalization of luxated teeth cannot be made due to a lack of clinical evidence. Patients with severe general medical
impairment (ASA 3 or higher) are also recommended to be treated by conventional approaches(24).
ClinicalProtocol
Revitalization usually takes place in two sessions. During the first session, a local anaesthetic is
administered, and the tooth is isolated with a dental dam. The necrotic tissue is removed from the
root canal, avoiding mechanical debridement of the canal walls. The length of the immature root
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