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88
U. Spandau
Fig. 7.6 After implantation of a hand painted Human Optics iris prosthesis into the sulcus
Fig. 7.7 An eye with an old traumatic mydriasis and natural lens
Video 7.2: Combo IOL-iris prosthesis (long
version).
Video 7.3: Combo IOL iris prosthesis in lens
capsule (short version).
Fig. 7.8 After implantation of a hand painted Human Optics iris prosthesis together with a 3-piece IOL into the lens capsule
Fig. 7.9 An aniridia and aphakia after a blunt perfora­tion with an i-pad
Instruments
10 mm corneal trephine (Opthec)
23G or 25G endgripping forceps
IOL injector
Material
Iris prosthesis (Human Optics)
MA60AC IOL (Alcon)
Fig. 7.10 Scleral fixation of a combined Human Optics iris prosthesis + 3-piece IOL
Fig. 7.11 Scleral fixation of a hard Opthec iris-IOL prosthesis (12 mm diameter)
897 Iris Surgery
Fig. 7.14 Cutting the Human Optics iris prosthe­sis (12 mm body) with a 10 mm trephine for sulcus implantation
Fig. 7.12 Intraoperative view on an eye with a recent traumatic mydriasis and aphakia after blunt trauma. The Hattenbach iris instruments in action
Fig. 7.13 After performing a purse string suture a ret­ropupillar iris-claw IOL is implanted. Postoperative VA = 1.0
Fig. 7.15 A 3-piece IOL (Alcon, AMO) will be com­bined with the foldable prosthesis
Fig. 7.16 The haptics of the 3-piece IOL were inserted into the iris prosthesis
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Fig. 7.17 The preoperative status after an explosive trauma. A healed corneal perforation, partial aniridia and aphakia
Fig. 7.18 Implantation of the combined iris prosthesis with 3-piece IOL with a regular IOL injector
Fig. 7.20 Immediate postoperative status. The 3-month postoperative VA = 0.4
Fig. 7.21 A recent traumatic mydriasis and aphakia after a blunt trauma with a plastic ball
Fig. 7.19 Scleral fixation of the IOL
Fig. 7.22 Insert the suture into the anterior chamber
with a Sinskey hook
Fig. 7.23 Purse string suture with Hattenbach iris instruments
917 Iris Surgery
Preparation of an iris-IOL prosthesis
The size of the iris prosthesis depends on an implantation in the sulcus or in the capsular bag. In case of a capsular bag implantation we use a
9.0 mm corneal trephine. In case of a sulcus implantation we use a 10.0 mm corneal trephine (Fig. 7.14). Place the 3-piece IOL on the backside of the foldable iris and place two incisions at each haptic with a 15 deg. knife (Alcon). Tunnel the 25G endgripping forceps through the two inci­sions, grab an end of a haptic and pull the hap­tic through the incisions (Figs. 7.15 and 7.16). Repeat the manoeuvre with the other haptic.
2. Insertion of iris-IOL prosthesis into a cartridge
3. Implantation of iris-IOL prosthesis
Fold or roll the combo prosthesis and insert it into an IOL cartridge (Alcon) and finally into an injector. Continue with a 2.4 mm main incision and implant then the combo iris-prosthesis into the anterior chamber (Fig. 7.18).
Fig. 7.24 After implantation of an Artisan IOL and closing the knot of the purse string suture. The 1-week postoperative VA = 0.9
Individual steps
Preparation of an iris-IOL prosthesis
Insertion of iris-IOL prosthesis into a
cartridge
Implantation of iris-IOL prosthesis
Fixation of iris prosthesis
The surgery step-by-step: Figs. 7.14, 7.15,
7.16, 7.17, 7.18, 7.19, and 7.20
4. Fixation of iris prosthesis
Rotate the combo iris-IOL prosthesis into the lens capsule. If a lens capsule is not pre­sent a scleral fixation has to be performed: (1) Intrascleral Scharioth method or (2) scleral fixation with sutures (Figs. 7.19 and 7.20). For details read the book “Complications during and after cataract surgery” from Ulrich Spandau and Gabor Scharioth.

Iridoplasty and Iris-Claw IOL Implantation

Video 7.4: Iridoplasty for traumatic mydriasis. Video 7.5: Iridoplasty for traumatic mydria-
sis + iris claw IOL.
Instruments
Iris instruments (Geuder)
23G or 25G intravitreal scissors
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Material
Onalene suture (Geuder)
Individual steps
1. Anterior chamber maintainer or pars plana infusion
2. Four paracentesis at 12, 3, 6 and 9 o’clock
3. Insert the Onalene suture into the anterior
chamber with a Sinskey hook
4. Perform a 360° suture around the pupil­lary margin (purse string suture)
5. Retropupillary implantation of the iris­claw IOL
6. Tying of the Onalene suture
The surgery step-by-step: Figs. 7.21, 7.22,
7.23 and 7.24.
1. Anterior chamber maintainer or pars plana
infusion
Place the needle behind the iris, pierce the tissue at the pupillary margin, grasp the needle with the second forceps and pull the needle com­pletely through. Continue 360°. Before tying the suture we must implant the IOL (Fig. 7.23). Alternatively you could tie the suture now and implant the iris-claw IOL antepupillary.
5. Retropupillary implantation of the iris-claw IOL
6. Tying of the Onalene suture
Perform a 6 mm broad incision at the limbus or at the sclera. Place the IOL on the iris and rotate the claws at the 3 and 9 o’clock position. Hold the IOL in an upside-down position with the IOL forceps (AMO), place the IOL behind the iris. Now the assistant must pull on both ends of the purse string suture so that the pupil is constricted. Using an iris spatula from Sekundo (Geuder) enclavate the iris tissue within the iris claws. Tie finally the purse string suture (Fig. 7.24).
Eyes with aphakia tend to be hypotony under surgery because the lens-iris diaphragma is impaired. In order to avoid intraoperative hypot­ony I recommend the use of an anterior chamber maintainer or even better a pars plana infusion. The anterior chamber maintainer may disturb the suturing within the anterior chamber.
2. Four paracentesis at 12, 3, 6 and 9 o’clock
3. Insert the Onalene suture into the anterior chamber
Perform a paracentesis at 12, 3, 6 and 9 o’clock. Then push the suture with a Sinskey hook (push–pull instrument) into the anterior chamber (Fig. 7.22).
4. Perform a 360° suture around the pupillary
margin (purse string suture)

Material and Companies Address

Opthec BV
Schweitzerlaan 15
9728 NR Groningen
Netherlands
Phone: + 31 050 5,251,944
www.opthec.com
Human Optics
Dr. Schmidt Intraocularlinsen GmbH
Westerwaldstraße 11–13
53,757 Sankt Augustin
Germany
e-mail: iris@humanoptics.com
http://www.artificial-iris.com
937 Iris Surgery
Geuder
Hertzstr. 4
69,126 Heidelberg
Germany
Tel: 06,221/3066
Fax: 06,221/303122
info@geuder.de
www.geuder.de
Part V
Cataract: Femto-Cataract, Laser
Phaco, Congenital Cataract
The most exciting development in cataract surgery is surely the advent of the laser. Prof. Nagy from Budapest, Hungary, is the developer of the femto cataract. He will present his technique step-by-step and show the pros and cons of this exciting new surgery. Dr. Sauder from Stuttgart, Germany, will demonstrate a novel phaco handpiece which removes the nucleus with laser instead of ultrasound. And finally will Dr. Nyström from Gothenburg, Sweden, demonstrate congenital cataract surgery with implantation of a Tassignon IOL.

Femtosecond Laser Assisted Cataract Surgery: Principles and Results

Zoltan Z. Nagy
8

Abstract

Ophthalmology always had a pioneer role in use of lasers (Light Amplification by Stimulated Emission of Radiation). A great variety of lasers have been employed since the first laser appeared within the ophthalmic armamentarium for more than 50 years. The German ophthalmolo­gist Meyer-Schwickerath applied the first laser for photocoagulation in the retina in 1949 (Meyer-Schwickerath in Ber Dtsch Ophthalmol Ges. 55:256–9, 1949). A laser is a special surgical device which emits spe­cific electromagnetic light via stimulated emission. Ophthalmic lasers operate at one specific fixed wavelength, pulse pattern, energy, duration, repetition rate, spot size and
The most exciting development in cataract surgery is surely the advent of the laser. Prof. Nagy from Budapest, Hungary, is a developer of femtosecond cataract surgery. He will present his technique step by step and show the pros and cons of this exciting new surgery.
Supplementary Information The online version contains supplementary material available at https://
doi.org/10.1007/978-3-031-84204-7_8.
Z. Z. Nagy (*) Director of Department of Ophthalmology, Semmelweis University, Budapest, Hungary e-mail: zoltan.nagy100@gmail.com
causing most of the time thermal effects, but photocoagulation, evaporation and non-ther­mal effects also important, regarding laser­tissue interaction.
Keywords
Optical coherence tomography · Femtosecond laser · Cataract surgery · Crystalline lens · Corneal incision
Ophthalmology always had a pioneer role in use of lasers (Light Amplification by Stimulated Emission of Radiation). A great variety of lasers have been employed since the first laser appeared within the ophthalmic armamentarium for more than 50 years. The German ophthal­mologist Meyer-Schwickerath applied the first laser for photocoagulation in the retina in 1949 [1]. A laser is a special surgical device which emits specific electromagnetic light via stimu­lated emission. Ophthalmic lasers operate at one specific fixed wavelength, pulse pattern, energy, duration, repetition rate, spot size and causing most of the time thermal effects, but photocoag­ulation, evaporation and non-thermal effects also important, regarding laser-tissue interaction.
Femtosecond lasers (Fig. 8.1) first applied in refractive surgery to replace mechanical and blade-operated microkeratomes to create
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2025 U. Spandau and G. B. Scharioth (eds.), Cutting Edge of Ophthalmic Surgery,
https://doi.org/10.1007/978-3-031-84204-7_8
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Z. Z. Nagy
Fig. 8.1 The Alcon-LenSx femtolaser. The left moni­tor is for to set the treatment parameters, the right LCD monitor helps the surgeon throughout the femtolaser
corneal flaps during laser in situ keratomileu­sis (LASIK) [2]. Thereafter the indication has changed and widened to all types of lamellar and penetrating keratoplasties, ring-segment implantation in keratoconus and presbyopia inlay pocket creation [3, 4].
The femtosecond laser beam is sharply focused and generates plasma within the affected corneal tissue. This plasma rapidly expands causing an acoustic shock wave and by this way displacing the surrounding tissue, cavi­tation bubbles and a cut plane are formed. At tis­sue level, photodisruption occurs exactly at the laser’s focal point without any thermal effect or collateral tissue damage. Due to the photo­disruptive effect, the femtolasers are capable of creating very precise cuts within the cornea, lens capsule and crystalline lens (Fig. 8.2) by the principle of tissue separation [5].
The repetition rate of femtosecond lasers has doubled recently from 30 to 60 kHz and recently a 160 kHz femtosecond laser has also became available, which is able to create a corneal flap within 10–12 s. The higher the repetition rate,
treatment, underneath the patient interface (PI) which comes into contact with the treated eye
the less energy is needed to achieve the same tissue effect. Femtosecond lasers used in laser assisted cataract surgery perform with a pulse duration of 400–800 femtosecond (fs) and the energy range is in micro Joules (106 J). During the surgery of the crystalline lens of the eye, the femtosecond laser energy is usually increased to 8–15 μJ.
The femtosecond laser generated plasma rap­idly expands causing an acoustic shock wave which displacing the surrounding tissue. When the plasma cools, cavitation bubbles are being formed [2, 3, 5]. At tissue level, photodisruption occurs without any thermal effect of the collat­eral tissue.
Cataract surgery at the moment is the most commonly performed ocular implantation pro­cedure not only within ophthalmology, but within medicine worldwide [6]. It is estimated that approximately 32 million cataract opera­tions will be performed globally by 2020 with a gradual increase year by year, due to aging population, demographic changes, and the change in indications for surgery [9]. Cataract
998 Femtosecond Laser Assisted...
Fig. 8.2 Screen of the Alcon-LenSx femtolaser
surgery and refractive surgery are being merged, so cataract surgery is not only a purely vision restoration entity, regarding the clarity of the optic media, but became a refractive procedure as well. Ophthalmic surgeons now also change the refractive power of the eye, compensate for astigmatism, spherical and other higher order aberrations of the eye. Further, the restoration of near vision has also become possible with the use of premium artificial lenses, such as multifo­cal or accommodating intraocular lenses [7, 8].
Patient expectation has also risen, doctors need to take longer chair time with patients explaining the benefits and drawbacks of dif­ferent surgical approaches and using different intraocular lenses. [10]. To avoid refractive sur­prises possible solutions include better intraocu­lar lens calculation using more precise formulas and performing a better and more thorough preoperative assessment, especially when the patient had refractive surgery before [11]. Now more consistent surgical results came in the
focus of ophthalmic community which is no longer depending on the dexterity of the sur­geon. In this field, femtolasers offer new possi­bilities and potential for surgeons and patients alike. Regarding the new trends in ophthalmol­ogy, compound and coupled diagnostic and sur­gical tools helping surgeons to achieve the final goal: the postoperative refraction should be within ± 0.5 Dpt to ± 0.25 Dpt as was achieved already in refractive surgery.

The Surgical Technique (Videos 8.1 and 8.2)

Docking Maneuver

The first and one of the most important steps of femtosecond laser assisted cataract surgery is the docking procedure with any types of femtosecond lasers. The Alcon-LenSx femto­second laser (Fig. 8.1) operates with a curved