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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_999_Библиотеки_им_академика_М_И_Перельмана

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graded I or II (without main duct injury) are treated conservatively. Main pancreatic duct (MPD) injury is the most important nding on the CT scan and operation is often the choice, although associated with high morbidity and mortality. Pancreatic injury can be associated with other abdominal lesions rendering conservative treat­ment less likely, notably after penetrating trauma. Despite the dearth of solid evi­dence, non-operative management (NOM) is increasing in this eld [5].
NOM in moderate and severe PI (grades III, IV, and V) has a success rate of 30% however with a high rate of subsequent pseudocysts, ranging from 65% to 74% [12]. Nevertheless these are mostly benign troubles amenable to minimally invasive interventions, particularly endoscopic drainage. After ERCP pancreatic stent inser­tion could be a successful strategy for grade III PI.
L. S. Coelho et al.
Main Duct Disruption
There is still not consensus on whether NOM is a legitimate approach for MPD. However, if delayed presentation with a well-walled pseudocyst is detected, MPD might benet from minimally invasive treatment nominally endoscopic cysto­gastrostomy. To this aim various models of stents contribute to keep the transmural drainage open till the cyst is reabsorbed.
Pancreatic Necrosis andAbscess
Acute pancreatitis is deemed as the most common cause, after gallbladder colic, of serious upper abdominal pain in clinical practice and although the vast majority of cases are mild and self-limited, up to 10% are associated with extensive pancreatic necrosis, which means high morbidity and prolonged hospital stay. In the relatively recent past it could carry a mortality rate of 30%, and even 70% with associated infection.
Pancreatic necrosis may present as an acute necrotic collection (ANC), usually seen in the rst 4 weeks and often extending into surrounding fat and retroperitoneal tissues, or walled-off necrosis (WON) which is a more mature, encapsulated pan­creatic mass seen 4 weeks or more after the onset of pancreatitis. In both circum­stances infection of the necrotic tissue is possible, eventually encompassing anaerobic bacteria [13].
Early laparotomy, debridement and drainage of infected pancreatic necrosis (IPN) was the established approach during many years, yet burdened by major com­plications (34–95%) and death (11–39%). Recent experience [14] demonstrates that non-operative treatment of IPN is the best alternative. In a series of 31 patients eight were treated with antibiotics only (25.8%), and the remaining ones were handled by drainage procedures (endoscopic and percutaneous). Surgical necrosectomy was
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necessary in only four patients (12.9%) because of treatment failure. Total mortality was 3.2% (01 death only).
The PANTER trial challenged open necrosectomy versus a less invasive approach named “step-up”, in which minimally invasive procedures can be escalated or re­employed for draining IPN.Such encompassed percutaneous drainage, endoscopic transgastric drainage, and minimally invasive retroperitoneal necrosectomy, gener­ally employed in this sequence.
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Percutaneous Drainage
Currently this represents indeed the rst line of treatment for IPN achieving 25–60% resolution of infection, with a high level of evidence (1A) [13]. Endoscopic trans­gastric drainage or necrosectomy and video-assisted retroperitoneal debridement are other alternatives, when required. Open surgery should be employed when those less invasive options fail as this approach relates to less new-onset organ failures, although it is more aggressive and may require more interventions.
In cases of disconnected duct syndrome with walled-off necrosis surgical trans­gastric necrosectomy may be also feasible, with morbidity and mortality around 38% and 2%, respectively [13].
Nonsurgical Pneumoperitoneum
Spontaneous nonlaparoscopy-related pneumoperitoneum indicates hollow viscus perforation and conventionally demands emergent surgical exploration. However, in 5% to 15% of cases it is not associated to perforation and may be conservatively managed.
Common andInfrequent Conditions
Early post-operative pneumoperitoneum can of course be detected after 60% of open surgeries and 25% of laparoscopic procedures. Around two-thirds of the nd­ings will resolve within 2 days and 97% after 5 days. On CT scan free peritoneal air may be recognized for somewhat longer, in about 50% of the cases after 6 days. A decreasing volume without worrisome clinical or peritoneal signs indicates a benign course.
Peritoneal dialysis can be associated with asymptomatic pneumoperitoneum (10–33% of the patients) [14]. Pneumatosis cystoides intestinalis is a rather rare cause of nonsurgical pneumoperitoneum. This condition is characterized by
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multiple intramural cysts lled with gas that may eventually rupture leading to pneumoperitoneum. Only in exceptional circumstances will intervention be required.
The lungs and thoracic structures may also be a source of nonsurgical pneumo­peritoneum as occasionally occurs during prolonged mechanical ventilation with pneumothorax or pneumomediastinum. Risk factors include high airway pressures, noncompliant lungs, obstructive airway disease, and acute respiratory distress syn­drome. Pneumoperitoneum in this setting, in the absence of peritoneal signs, could lead to unnecessary imaging investigation and even laparotomy [14].
Although unusually air may enter the peritoneal cavity from the genital tract through the uterus and uterine tubes. Tubal insufation during an hysterosalpingo­gram is an obvious mechanism; however, other local manipulations including sex­ual intercourse could be possible causes. Spontaneous resolution is the rule [14]. Only in circumstances of signicant pain or rebound tenderness, fever, elevated white blood cell count, or other signs of peritoneal inammation should additional work be provided.
L. S. Coelho et al.
Case Report
As previously alluded to, non-operative treatment of infected pancreatic necrosis is the preferred approach nowadays. Especially when percutaneous or endoscopic catheter drainage of the septic focus is feasible, and material can be collected for bacteriologic prole and targeted antibiotic therapy. More than three decades ago interventional radiology and endoscopy were not as available and effective in this condition as nowadays. Mortality with strictly conservative therapy was prohibitive, therefore nearly all services advocated urgent open drainage. A patient seen by one of the authors [15] was a profoundly religious man admitted to an academic hospital.
The involved microbes could not be identied as initial blood cultures were neg­ative, and minimally invasive access to the focus was not available at that time. However, the individual was clinically septic with fever, high white blood cell count, upper abdominal distention and pain, and gas bubbles were identied during the imaging exploration of the pancreatic area, along with extensive retroperitoneal necrosis. As the case was being prepared for operative handling the patient ada­mantly refused surgical consent. In his opinion either his faith would save him, or otherwise he would peacefully accept that his time of dying has arrived. As he offered no alternative intravenous nutrients and high doses of antibiotics were pre­scribed, and the medical team crossed ngers hoping for the best. “After the second week the patient rapidly started to improve, to the point that he could be discharged home without operation” [15]. To the best of our knowledge, it was the rst report of full regression with medical management only.
Not surprisingly the article was subsequently criticized, not only on account of lack of bacteriologic conrmation, but because the concept of non-operative recov­ery after such an ominous infection was unconscionable at that time. Only about a
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decade later did that pathway start to become mainstream and now of course it’s commonplace, provided minimally invasive drainage is also accomplished.
We agree that our rst plan had not been medical care either, as in the 1980s and 1990s of last century minimally invasive approaches were mostly a distant horizon, and even well-equipped surgical intensive care units (SICUs) were not easy to come by. Only today can one be condent that a critically ill subject will be well moni­tored when admitted to a SICU.Should conservative therapy fail and unexpected deterioration occur, the surgeon will still be able to change course and provide the required operation.
References
1. Chung KT, Shelat VG. Perforated peptic ulcer—an update. World J Gastrointest Surg. 2017;9(1):1–12. https://doi.org/10.4240/wjgs.v9.i1.1.
2. Salminen P, Tuominen R, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Hurme S, Mecklin JP, Sand J, Virtanen J, Jartti A, Grönroos JM. Five-year follow-up of antibi­otic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA. 2018;320(12):1259–65. https://doi.org/10.1001/jama.2018.13201. Erratum in: JAMA 2018 Oct 23;320(16):1711. PMID: 30264120; PMCID: PMC6233612
3. Wei JJ, Xie XP, Lian TT, Yang ZY, Pan YF, Lin ZL, Zheng GW, Zhuang ZH.Over-the-scope­clip applications for perforated peptic ulcer. Surg Endosc. 2019;33(12):4122–7. https://doi.
org/10.1007/s00464- 019- 06717- x.
4. de’Angelis N, Di Saverio S, Chiara O, etal. WSES guidelines for the management of iatro­genic colonoscopy perforation. World J Emerg Surg. 2017;2018(13):5. https://doi.org/10.1186/
s13017- 018- 0162- 9.
5. Koganti SB, Kongara R, Boddepalli S, Mohammad NS, Thumma V, Nagari B, Sastry RA.Predictors of successful non-operative management of grade III & IV blunt pancreatic trauma. Ann Med Surg (Lond). 2016;10:103–9. https://doi.org/10.1016/j.amsu.2016.08.003.
6. Khan A, Hawkins AT.Challenging surgical dogma: controversies in diverticulitis. Surg Clin North Am. 2021;101(6):967–80. https://doi.org/10.1016/j.suc.2021.05.024.
7. Fugazzola P, Ceresoli M, Coccolini F, Gabrielli F, Puzziello A, Monzani F, Amato B, Sganga G, Sartelli M, Menichetti F, Puglisi GA, Tartaglia D, Carcoforo P, Avenia N, Kluger Y, Paolillo C, Zago M, Leppäniemi A, Tomasoni M, Cobianchi L, Dal Mas F, Improta M, Moore EE, Peitzman AB, Sugrue M, Agnoletti V, Fraga GP, Weber DG, Damaskos D, Abu-Zidan FM, Wani I, Kirkpatrick AW, Pikoulis M, Pararas N, Tan E, Broek RT, Maier RV, Davies RJ, Kashuk J, Shelat VG, Mere AC, Augustin G, Magnone S, Poiasina E, De Simone B, Chiarugi M, Bif W, Baiocchi GL, Catena F, Ansaloni L.The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly. World J Emerg Surg. 2022;17(1):5.
8. Cinquantini F, Simonini E, Di Saverio S, Cecchelli C, Kwan SH, Ponti F, Coniglio C, Tugnoli G, Torricelli P. Non-surgical management of blunt splenic trauma: a comparative analysis of non-operative management and splenic artery embolization-experience from a european trauma center. Cardiovasc Intervent Radiol. 2018;41(9):1324–32. https://doi.org/10.1007/
s00270- 018- 1953- 9.
9. Coccolini F, Montori G, Catena F, Kluger Y, Bif W, Moore EE, Reva V, Bing C, Bala M, Fugazzola P, Bahouth H, Marzi I, Velmahos G, Ivatury R, Soreide K, Horer T, Ten Broek R, Pereira BM, Fraga GP, Inaba K, Kashuk J, Parry N, Masiakos PT, Mylonas KS, Kirkpatrick A, Abu-Zidan F, Gomes CA, Benatti SV, Naidoo N, Salvetti F, Maccatrozzo S, Agnoletti V, Gamberini E, Solaini L, Costanzo A, Celotti A, Tomasoni M, Khokha V, Arvieux C, Napolitano
https://doi.org/10.1186/s13017- 022- 00408- 0.
470
https://t.me/med1917
L, Handolin L, Pisano M, Magnone S, Spain DA, de Moya M, Davis KA, De Angelis N, Leppaniemi A, Ferrada P, Lati R, Navarro DC, Otomo Y, Coimbra R, Maier RV, Moore F, Rizoli S, Sakakushev B, Galante JM, Chiara O, Cimbanassi S, Mere AC, Weber D, Ceresoli M, Peitzman AB, Wehlie L, Sartelli M, Di Saverio S, Ansaloni L.Splenic trauma: WSES clas­sication and guidelines for adult and pediatric patients. World J Emerg Surg. 2017;12:40.
https://doi.org/10.1186/s13017- 017- 0151- 4.
10. Pillai AS, Kumar G, Pillai AK. Hepatic trauma interventions. Semin Intervent Radiol. 2021;38(1):96–104.
11. Coccolini F, Coimbra R, Ordonez C, Kluger Y, Vega F, Moore EE, Bif W, Peitzman A, Horer T, Abu-Zidan FM, Sartelli M, Fraga GP, Cicuttin E, Ansaloni L, Parra MW, Millán M, DeAngelis N, Inaba K, Velmahos G, Maier R, Khokha V, Sakakushev B, Augustin G, di Saverio S, Pikoulis E, Chirica M, Reva V, Leppaniemi A, Manchev V, Chiarugi M, Damaskos D, Weber D, Parry N, Demetrashvili Z, Civil I, Napolitano L, Corbella D, Catena F, WSES Expert Panel. Liver trauma: WSES 2020 guidelines. World J Emerg Surg. 2020;15(1):24.
https://doi.org/10.1186/s13017- 020- 00302- 7.
12. Coccolini F, Kobayashi L, Kluger Y, etal. Duodeno-pancreatic and extrahepatic biliary tree trauma: WSES-AAST guidelines. World J Emerg Surg. 2019;14:56. https://doi.org/10.1186/
s13017- 019- 0278- 6.
13. Leppäniemi A, Tolonen M, Tarasconi A, Segovia-Lohse H, Gamberini E, Kirkpatrick AW, Ball CG, Parry N, Sartelli M, Wolbrink D, van Goor H, Baiocchi G, Ansaloni L, Bif W, Coccolini F, Di Saverio S, Kluger Y, Moore E, Catena F. 2019 WSES guidelines for the management of severe acute pancreatitis. World J Emerg Surg. 2019;14:27. https://doi.org/10.1186/
s13017- 019- 0247- 0.
14. Mularski RA, Sippel JM, Osborne ML.Pneumoperitoneum: a review of nonsurgical causes. Crit Care Med. 2000;28(7):2638–44.
15. Faintuch J, Meniconi MT, Speranzini MB, Pinotti HW, Smolentsov H.Clinical regression of infected pancreatic necrosis: case report. Int J Pancreatol. 1991;8(4):379–86. https://doi.
org/10.1007/BF02952729.
https://doi.org/10.1055/s- 0041- 1724014.
https://doi.org/10.1097/00003246- 200007000- 00078.
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Part VII
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Bedside and Adjunct Procedures
Chapter 28
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Percutaneous Ultrasound-Guided Gastrostomy Placement
SamuelB.Fordyce, RooshiK.Parikh, andStephenP.Reis
Introduction
Surgical techniques for gastrostomy tubes were rst developed in the 1800s, with most of the test subjects perishing due to infection prior to the advent of antibiotics. Fast forward to 1969, two surgeons, Dr. Jeffery Ponsky and Dr. Michael Gauderer, devised and performed the rst percutaneous endoscopic gastrostomy tube place­ment [1]. Other minimally invasive techniques, such as uoroscopic and ultrasound­guided techniques, were subsequently developed. Today, approximately 250,000 gastrostomy tubes are placed annually in the United States alone [2]. With our ever­aging population and medical capabilities allowing patients to live longer lives, gas­trostomy tubes are becoming a vital part of the treatment algorithm, particularly for critically ill patients. The most recently developed technique, ultrasound-guided gastrostomy tube placement, has become a widely adopted technique that holds specic advantages. Apart from surgical approaches for gastrostomy tube place­ment, open or laparoscopic routes, minimally invasive techniques (endoscopic, uo­roscopic, and ultrasound) are widely preferred, secondary to their low complication risk and lack of general anesthesia; however, they still require special equipment, trained practitioners, and dedicated endoscopic/uoroscopic suites.
On the other hand, percutaneous ultrasound-guided gastrostomy tube placement
has been shown to be effective and safe as a bedside option, using readily available
S. B. Fordyce (*) · S. P. Reis Department of Interventional Radiology, Columbia University Irving Medical Center, New York, NY, USA e-mail: saf9141@nyp.org; sr3321@cumc.columbia.edu
R. K. Parikh City University of NewYork School of Medicine, New York, NY, USA e-mail: rparikh000@citymail.cuny.edu
Switzerland AG 2024 J. Faintuch, S. Faintuch (eds.), Recent Strategies in High Risk Surgery,
https://doi.org/10.1007/978-3-031-56270-9_28
473© The Author(s), under exclusive license to Springer Nature
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S. B. Fordyce et al.
technology, thereby reducing complications and inconveniences such as transporta­tion of patients [2]. Depending on the specic patient and medical reasoning behind placing a gastrostomy tube, all of the techniques mentioned below have their advan­tages and disadvantages.
Indications
The main indication for gastrostomy tube placement is the need for supplemental nutrition secondary to insufcient oral intake, contraindication to oral intake through the mouth or gastric decompression; however, there are nuances that need to be carefully considered prior to gastrostomy tube placement [3]. Assuming patients have acceptable baseline nutritional status, they can tolerate up to 10 days of partial fasting prior to signicant protein catabolism [3]. On the other hand, patients with chronic illnesses that previously inhibited their oral intake abilities may require the initiation of nutritional support sooner.
Enteral feedings options are most commonly split between nasoenteric and gas­troenteric techniques. Typically, nasoenteric options, namely nasogastric tubes, are reserved for short-term enteric supplementation of acutely ill patients, such as immediately postoperatively. Nasogastric tubes have their advantages: they areeas­ily placed and arefairly low risk. As mentioned above, acutely ill patients or patients expected to make a full recovery can benet from short-term enteral supplementa­tion and gastric decompression without the need for an invasive procedure; how­ever, there are several disadvantages. Nasoenteric alternatives can be associated with skin irritation, gastroesophageal reux, bleeding, and ulceration, especially with use greater than 2 weeks [3, 4]. Gastrostomy tube placement forgoes many of these complications; however, the procedure itself is more invasive and can lead to complications. One cited reason for gastrostomy tube placement over nasoenteric techniques is the possible reduction of aspiration risk [5, 6].
Patients at a moderate to high risk of malnourishment requiring nutritional sup­port greater than 30days should consider placement of a gastrostomy tube [3, 7]. A wide variety of conditions/diagnosis are referred for gastrostomy tube placement (Table28.1); it is important to carefully assess an individual patient’s needs, includ­ing preferences, diagnosis, goals, and life expectancy. Quality of life should remain a priority.
Table 28.1 Referral diagnosis for gastrostomy tube placement
Neurological disorders Malignancy
Congenital or acquired neurological disordersinterfering with ability to ingest food
Head and neck, esophagus, upper abdomen, brain
Congenital and neonatal Miscellaneous
Cystic brosis, low birth weight, congenital heart disorders
Trauma including traumatic brain injury, burns especially involving face, dysphagia, other digestive aberrations, palliative care
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Aspiration Pneumonia
Aspiration pneumonia is the most commonly cited cause of mortality in patients with nasogastric or gastrostomy tubes [6, 8, 9]. Originally, one of the main presumed advantages of gastrostomy over nasogastric tubes was decreased events of aspiration pneumonia. Purely from an anatomical and technical perspective, this assumption makes sense. Nasogastric tubes extend from the patient’s nares, through the gastro­esophageal sphincter and into the stomach. This keeps the gastroesophageal sphinc­ter partially open, thereby increasing the likelihood of aspiration, especially in chronically ill patients with impaired normal functions. Gastrostomy tubes forgo the need to keep the gastroesophageal sphincter open, which prevents aspiration. Contrary to anatomical logic, past studies and meta-analyses have been unable to elicit statistically signicant differences for incidences of aspiration pneumo­niabetween nasoenteric and gastroenteric techniques [10]. On the other hand, dys­phagia secondary to stroke, gastrostomy tube placement reduced the risk of aspiration by almost ve times, compared to nasogastric tube placement [11]. Regardless of such results, it is well known that both increase the risk compared to patients without either, and it shouldbe considered in the decision-making process [12].
Dementia
Most experts agree that the incidence and prevalence of dementia will proportion­ally increase with a continuously aging population [13]. A majority of these patients, more than 90%, have dysphagia or other oral intake problems, leading to the place­ment of long-term enteral feeding options, like gastrostomy tubes, which are con­sidered a prognostic indicator of mortality within a 6-month time period [14]. Patients with dementia who undergo a gastrostomy tube placement have a mortality rate of up to 54% after 1 month and 90% after 1 year [15]. For these reasons, quality of life and improvement in mortality should be of paramount importance [8].
Periprocedural Care andPatient Preparation
Pre-Procedural Care
It’s important to conduct a comprehensive physical exam prior to any gastrostomy procedure to ensure certain modalities are not precluded. The oropharynx needs to be evaluated for anatomical variants, congenital anomalies, and facial fractures, which would increase the risk for an endoscopic approach [16]. The endoscopic route with partially obstructing head and neck malignancies is contraindicated and infeasible. Certain conditions may increase procedural complexity, for example, obesity, ascites, and neurological disorders. Any prior imaging and/or obtaining
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Table 28.2
placement techniques
Technique PUG PRG PEG
Advantages
Disadvantages
Comparison of the advantages and disadvantages of the various gastrostomy tube
– Performed at
bedside
– Shorter ICU and
hospital length of
stay – Cost savings – No radiation
exposure – Longer procedure
length – Inadequate
gastropexy with
larger patients
– Shorter procedure
length
– Better visualization
of gastric insufation
– No cross-
contamination of oral ora
– Radiation exposure – Requirement of a
uoroscopy suite
– Shorter procedure
time – Possible at bedside – No radiation
exposure
– Inadequate
transillumination in
obese patients – No direct
visualization of
intercepting bowel or
liver – Risk of gastrostomy
tract tumor seeding
further imaging is advised if you suspect or know of altered anatomy from prior surgery [16, 17]. The delineation of hepatic and colonic anatomy can be a priority as well. Certain patients may warrant pre-procedural ultrasound to delineate the liver edge in order to ensure it isn’t accidentally punctured (Table28.2).
Typically, patients are required to be nothing by mouth (NPO) or nothing per nasogastric tube for 6–8h prior to the procedure, mainly due to aspiration risk sec­ondary to anesthesia, whether that is moderate or general anesthesia. Additionally, most policies require patients to ingest oral contrast (Barium) 12–24h prior to the procedure to elucidate colonic anatomy, particularly the transverse colon. Alternatively, patients may be given pre-procedural rectal contrast instead of oral contrast to ensure the transverse colon is clear of the potential needle path.
Antibiotic Prophylaxis
As a “clean-contaminated” procedure, antibiotic prophylaxis has long been stan­dard of practice, as it reduces periprocedural infections, particularly peristomal infections [18]. The guidelines dictating appropriate antibiotic prophylaxis are var­ied and technique specic. According to the Society of Interventional Radiology (SIR), Standards of Practice Committee (SPC), and American Society for Gastrointestinal Endoscopy (ASGE), 1g of cefazolin is recommended for the “pull” uoroscopic and endoscopic-guided techniques, since traversing the oropharynx or nasopharynx is thought to seed bacteria within the stomach and skin tunnel. Special considerations should be considered for patients with head and neck cancer with potential bacterial overgrowth from an obstructing malignancy. Per SIR guidelines, second generation cephalosporins should be used for prophylaxis followed by an oral course of a rst generation of cephalosporins [18] (Table 28.3). There is