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About the Editors
Prakash Katakam is a pharmaceutical scientist working as
professor and principal at Indira College of Pharmacy, Nanded,
India. He has more than 27 years of professional experience
as a teacher and researcher. He published over 150 research
articles in indexed journals and guided 14 PhD students. His
research areas are 3D printing for personalized drug delivery,
pulmonary delivery of vaccines, micro/ nanoparticles, phytoformulations and drug discovery. He is the founder of a research
laboratory on 3D printing, RxPrints Lab, 3DFying Inc.,
Hyderabad, India and Awarded for his invention, “Indigenous
3D Printer Customized Medicine and Pharmaceutics of the Year
2023”, by IIT Bombay, India. His major research focus is on
identifying applications of various polymers for 3D printing for
patient- specic dosage forms. He has been co- principal investigator for a sponsored research
project of National Tea Research Foundation, India. Recently he contributed a publication on
“Navigating the Challenges of 3D Printing Personalized Medicine in Space Explorations: A
Comprehensive Review” in Critical Reviews in Therapeutic Drug Carrier Systems Journal
and a book chapter “Recent Advancements of Additive Manufacturing for Patient- Specic
Drug Delivery” in the book, “Additive Manufacturing Processes in Biomedical Engineering”,
published by CRC Press (Taylor & Francis Group). Dr. Katakam also published a highly cited
review article, “Top- Down and Bottom- Up Approaches in 3D Printing Technologies for Drug
Delivery Challenges” in the journal Critical Reviews in Therapeutic Drug Carrier Systems.
Ranvijay Kumar is an assistant professor at the Marwadi
University Research Center, Marwadi University, Rajkot,
India. He received a PhD in Mechanical Engineering
from Punjabi University, Patiala. Additive manufacturing,
shape memory polymers, smart materials, friction- based
welding techniques, advanced materials processing,
polymer matrix composite preparations, reinforced
polymer composites for 3D printing, plastic solid waste
management, thermosetting recycling, and destructive
testing of materials are Dr. Kumar’s expertise. Dr. Kumar
has won the prestigious CII MILCA award in 2020. He
has co- authored more than 43 research papers in science
citation indexed journals, and 38 book chapters, and has presented 20 research papers
at various national/ international- level conferences. He has contributed extensively
to the additive manufacturing literature with publications appearing in Journal of
Manufacturing Processes, Composite Part: B, Rapid Prototyping Journal, Journal
of Thermoplastic Composite Materials, Measurement, Proceedings of the Institution
of Mechanical Engineers, Part C (iMeche Part C), Proceedings of the Institution
of Mechanical Engineers, Part H: Journal of Engineering in Medicine, Journal of
Thermoplastic Composite Materials, Materials Research Express, Proceedings of
the National Academy of Sciences, India Section A: Physical Sciences, Journal of
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About the Editors
Central South University, Journal of the Brazilian Society of Mechanical Sciences
and Engineering, Composite Structures, and CIRP Journal of Manufacturing Science
and Technology. He is the editor of the book “Additive Manufacturing for Plastic
Recycling: Efforts in Boosting A Circular Economy” publishing by CRC Press
(Taylor & Francis Group).
Nishant Ranjan is an assistant professor at the Marwadi
University Research Center, Marwadi University, Rajkot,
India. Dr. Ranjan has won the prestigious CII MILCA
award in 2022. Fused deposition-modeling, extrusion,
thermoplastic polymers, Polymer Composites, natural
and synthetic biopolymers, scaffolds printing, 3D printing
technology, thermal, mechanical, morphological, and
chemical properties of thermoplastic polymers,
biocompatible and biodegradable llers, and reinforcement
of materials are the main areas of focus for Dr. Ranjan.
He has co-authored more than 40 research papers in
science citation index journals, 35 book chapters, 2 books
and presented more than 10 research papers at various national/international
conferences.
Atul Babbar is an assistant professor at the Mechanical
Engineering Department of SGT University, Gurugram.
He has taught students in academics and research elds.
He is a a level 2 non- destructive testing engineer certied
by the American Society of Non- Destructive Testing
(ASNT). His research interests include biomedicals,
3D and 4D printing, conventional/ non- conventional
machining and not limited to that. He has authored
several research articles and book chapters in various
international/ national SCI and Scopus journals. He has
reviewed research articles of various peer- reviewed SCI
and Scopus indexed journals.
https://t.me/med1917
Contributors
Shanta Kumari Adiki
Rajarshi Shahu College of Pharmacy
Markhel
Maharashtra, India
Mohit Agrawal
School of Medical & Allied Sciences
K.R. Mangalam University
Gurugram, India
Swamita Arora
Department of Pharmacy
R.V. Northland Institute
Greater Noida, India
Swati Arya
SGT College of Pharmacy,
SGT University
Haryana, India
Ravi Shankar Ayyanar
Commissioner of Police
Commissioner of Police Bungalow
Andhra Pradesh, India
Kondabrolu Naga Bhargavi
KVSR Siddhartha College of
Pharmaceutical Sciences
Andhra Pradesh, India
P. Sunil Kumar Chaitanya
St. Pauls College of Pharmacy
Telangana, India
Somnath De
St. Pauls College of Pharmacy
Telangana, India
Bhoopathi Deepika
St. Pauls College of Pharmacy
Telangana, India
Tulja Rani Gampa
Department of Pharmaceutical Analysis
Malla Reddy Pharmacy College
Telangana, India
Md. Sadique Hussain
School of Pharmaceutical Sciences
Jaipur National University
Jaipur, India
J Joysa Ruby
Acharya & BM Reddy College of
Pharmacy
Karnataka, India
Keerthi Kadimcharla
National Institute of
PharmaceuticalEducation and
Research (NIPER)
Telangana, India
Sudarshan Kakad
AETs St. John Institute of Pharmacy
and Research
Maharashtra, India
Hema Chaudhary
School of Medical & Allied Sciences
K.R. Mangalam University
Gurugram, India
Raja Rajeswari Kamisetti
Vardhaman College of Pharmacy
Maharashtra, India
Naga Raju Kandukoori
St. Pauls College of Pharmacy
Telangana, India
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Prakash Katakam
Indira College of Pharmacy
Maharashtra, India
and
RxPrints Lab, 3DFying, Inc.
Hyderabad, India
Venu Madhav Katla
St. Pauls College of Pharmacy
Telangana, India
Adarsh Keshari
Department of Pharmacy
Practice Teerthanker Mahaveer
College of Pharmacy
Teerthanker Mahaveer University
Moradabad, India
Kakani Anil Kumar
Assistant Professor, Department of
Pharmaceutics and Biotechnology
KVSR Siddhartha College of
Pharmaceutical Sciences
Andhra Pradesh, India
Shivendra Kumar
Department of Pharmacy
Rajiv Academy for Pharmacy
Mathura, India
Bhavaraju Lakshmi Ratna
Madhavi
Acharya & BM Reddy College of
Pharmacy
Karnataka, India
Kiranmai Mandava
Department of Pharmaceutical
Chemistry
St. Paul’s College of Pharmacy
Telangana, India
Contributors
Vijaya Lakshmi Marella
Associate Professor, Department of
Pharmaceutical Analysis
KVSR Siddhartha College of
Pharmaceutical Sciences
Andhra Pradesh, India
Popat Mohite
AETs St. John Institute of Pharmacy
and Research
Maharashtra, India
Kanaka Durga Devi Nelluri
Associate Professor, Department of
Pharmaceutics and Biotechnology
KVSR Siddhartha College of
Pharmaceutical Sciences
Andhra Pradesh, India
Naga Haritha Pamujula
St. Pauls College of Pharmacy
Telangana, India
Aakriti Patel
Bengal college of Pharmaceutical
Sciences and Research
West Bengal, India
Neha Pathak
Department of Pharmacy
Practice, Teerthanker Mahaveer
College of Pharmacy
Teerthanker Mahaveer University
Moradabad, India
Rashmi Pathak
Department of Pharmacy, Invertis
University
Bareilly, India
Anil Pawar
MES’s College of Pharmacy
Maharashtra, India
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Contributors
Bhupendra Prajapati
Shree S. K. Patel College of
Pharmaceutical Education and
Research
Ganpat University
Kherva, India
Sk. Abdul Rahaman
School of Pharmacy
Galgotias University
Uttar Pradesh, India
Ajmeer Ramkishan
Deputy Drugs Controller- India
CDSCO, Hyderabad Zonal Ofce
Hyderabad, India
Sameer Rastogi
School of Pharmacy
Noida International University
Greater Noida, India
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Himanshu Sharma
Department of Pharmacology
Teerthanker Mahaveer College of
Pharmacy
Teerthanker Mahaveer University
Moradabad, India
Vijay Kumar Sharma
Dr. K.N. Modi Institute of
Pharmaceutical Education &
Research
Uttar Pradesh, India
Aastha Singh
Dreams College of Pharmacy
Uttar Pradesh, India
Kuldeep Singh
Department of Pharmacy
Rajiv Academy for Pharmacy
Mathura, India
Nensi Raytthatha
Gujarat Technological University
Gujarat, India
Sunam Saha
Department of Pharmacy
Rajiv Academy for Pharmacy
Mathura, India
Subhas Sahoo
Pulla Reddy Institute of Pharmacy
Telangana, India
Sowmyaranjan Satapathy
DFE Pharma India Pvt. ltd.
Telangana, India
Manoj Shahare
Novartis Health Care Pvt. Ltd.
Telangana, India
Sudarshan Singh
Faculty of Pharmacy and Ofce of
Research Administration
Chiang Mai University
Chiang Mai, Thailand
Nagarajan Sriram
Florence College of Pharmacy, Ranchi
Jharkhand, India
Sneha Thakur
Department of Pharmacognosy
St.Pauls College of Pharmacy
Telangana, India
Siddhant Jai Tyagi
Department of Pharmacology
Teerthanker Mahveer College of
Pharmacy
Teerhanker Mahaveer University
Moradabad, India
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Prakhar Varshney
Department of Pharmacology
Teerthanker Mahaveer
College of Pharmacy
Teerthanker Mahaveer University
Moradabad, India
Contributors
Jigar Vyas
Faculty of Pharmacy
Sigma University
Gujarat, India
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Section I
3D Printing, Drug Delivery
Systems, and Application
Domain Overview
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Advancements in
1
Tailoring Medication
Using 3D Printing
Bhavaraju Lakshmi Ratna Madhavi, J Joysa Ruby,
Prakash Katakam, Ravi Shankar Ayyanar, and
Shanta Kumari Adiki
1.1 INTRODUCTION
In the realm of modern medicine, a groundbreaking convergence of technology and
healthcare is redening the way we approach diagnosis, treatment, and patient care.
At the forefront of this revolution stands three- dimensional printing (3DP), a cuttingedge manufacturing technique that has transcended its industrial roots to become an
invaluable asset in the eld of personalized medicine (Vaz and Kumar, 2021; Mathew
et al., 2020). 3DP, with its ability to create intricate three- dimensional objects layer
by layer from digital designs, is offering tailored solutions to individual patients.
Medical treatment, once characterized by a one- size- ts- all approach, is now being
driven by the recognition of individual uniqueness. Patients vary not only in their
medical conditions but also in their anatomical structures, genetic compositions, and
treatment responses. Traditional standardized treatments often fall short in addressing
the intricacies of each patient’s condition, leading to suboptimal outcomes and
prolonged recovery times. 3DP technology promises an unprecedented level of personalization into medical care.
Conventional/ traditional medicine refers to the mainstream healthcare practices
that have been in use for centuries, often based on empirical knowledge, population
pharmacokinetics and standardized treatment approaches. The fundamental premise
of personalized medicine is simple yet profound: no two individuals are alike. Every
patient carries a unique genetic makeup, medical history, and set of circumstances
that inuence their health journey. Yet, for decades, medical interventions have
largely adhered to standardized protocols, treating patients as statistical averages
rather than singular entities. The emergence of 3DP, introduces a paradigm shift
that aligns seamlessly with the ethos of personalized medicine. Personalized medicine is an approach to improve therapy or prophylaxis designed specically for each
patient. It uses a person’s genetic and epigenetic details and takes special care about
their preferred choices, faith, attitudes, knowledge and societal inuences. Precision
medicine is a deeper extent of personalized medicine, the basis of which relies on
data from many sources like genomics, biological information, transcriptomics and
3DOI: 10.1201/9781003439509-2
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