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Management
Patients with differentiated abdominal pain require treatment that is often individualized and directed at the underlying disease. This makes treatment of these patients in the OU somewhat more compli­cated. As mentioned earlier, it is important to define clear goals of care prior to placing these patients in the OU. Often it is necessary to consult subspecialty services prior to placing the patient in the OU. For example, a patient with a flare of Cohn’s disease with no clear need for admission may be treated with antibiotics, steroids, and pain control. Alternatively, a patient with gastroparesis who presents with abdominal pain may be treated with IV fluids, pain control, and bowel rest. Post­procedural patients often present to the ED with abdominal pain and fall into this category. Post­endoscopy patients with abdominal pain and bloating can be treated with IV fluids, pain control, and bowel rest. In general, treatment of differenti­ated abdominal pain focuses on the following prin­ciples: treatment of underlying disease process, pain control, and managing diet.
Disease-specific care
Inflammator y Bowel Diseas e
Patients with inflammatory bowel disease often pre­sent with abdominal pain flares. This is frequently accompanied by diarrhea and nausea. Many of these patients will have severe symptoms that require inpatient treatment. Patients with known or suspected abscess, concern for obstruction or perforation, surgical abdomen or signs of severe infection require treatment as an inpatient. Patients with moderate disease with good outpatient follow­up are good candidates for observation treatment. It may be necessary to obtain a CT scan or MRI of the abdomen and pelvis in the ED to determine the extent of disease prior to disposition.
1,2
Treatment of these patients may include the following: steroids, pain control, antibiotics, and antiemetics.
1,2
The primary endpoint in this patient population is pain control and ability to tolerate PO. It is often helpful to discuss the case with the patientsoutpatient physician at some point prior to discharge, as these patients often require close follow-up.
Postprocedural Abdominal Pain
Postprocedural patients will often develop abdom­inal pain. This can occur after upper and lower
endoscopy and minor surgery.
3
There are multiple sources of pain in these patients including bloating from endoscopy, anesthesia, constipation related to opioid medications, and the underlying process. Treatment for this patient population often includes bowel rest, IV fluids, and pain control. It is often necessary to obtain an abdom­inal plain film to rule out free air. Diet should be slowly advanced. Care should be coordinated with the procedural provider. The patient can be dis­charged when they are tolerating PO and their pain is controlled.
Gastroparesis
Patients with gastroparesis frequently have exacerbations or flares of their symptoms. These flares have many triggers including hypergly­cemia, infection, diet, and medication noncom­pliance. These patients often complain of severe abdominal pain, nausea, and vomiting.
4
They often present with signs of dehydration. Some of these p atients can be safely managed in an OU. Treatmen t of this group of patients usually involve s pain control, antiemetics, and IV fluids. Prokinetic medications such as meto­clopramide may improve symptoms.
5
Their diet should be slowly advanced. This group can be discharged when their pain is controlled and they are tolerating PO intake. Patients with cyclic vomiting syndrome and chronic abdominal pain can often be treated in a similar manner.
Outcome
The primary goal in this patient population is improvement in symptoms. It is unlikely that the abdominal pain will completely resolve, but rather the goal is that the pain is manageable. In addition, patients should be able to tolerate PO intake and should have an outpatient follow-up plan. Patients whose pain is not controlled, are unable to tolerate PO, or who require further testing despite treatment in the OU should be made inpatient status.
Conclusion
Patients with differentiated abdominal pain can often be appropriately treated in an OU. This population is diverse and often requires an indi­vidualized care plan. It is often necessary to consult
Abdominal Pain
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or discuss with subspecialty services to ensure that an appropriate plan is established. The primary goals and outcomes in this population include
the following: pain management, nausea control, diet management, and establishing outpatient follow-up.
References
1. Carter M, Lobo A, Travis S. Guidelines for the management of inflammatory bowel disease in adults. Gut. 2004. 53: v1–v16.
2. Lichtenstein G, Hanauer S, Sandborn W. Management of Crohnsdiseaseinadults.ACG practice guidelines. American Journal of Gastroenterology. 2004.
3. Ko C, Riffle S. Incidence of minor complications and time lost of time from minor complications after screening colonoscopy. Gastrointestinal Endoscopy. 2007. Apr(4): 648–656.
4. Cherian D, Sachcheva P, Fisher RS, et al. Abdominal pain is a frequent symptom of
gastroparesis. Clinical
Gastroenterology and Hepatology. 2010. Aug(8):
678–681.
5. Parkham H, Hasler W, Fisher R. Diagnosis and treatment of gastroparesis. AGA medical position statement. Gastroenterology. 2004. Nov(127), issue 5: 1589–1591.
Mark G. Moseley and Miles P. Hawley
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Subpart IVM
Chapter
57
Clinical – Pain Management and Musculoskeletal
Pain Management, Including Musculoskeletal and Low Back Pain
Nathaniel L. Scott, MD, FACEP James R. Miner, MD, FACEP
Introduction
Pain management is often an important part of treatment in an observation unit (OU). This chap­ter will discuss general principles of the treatment of pain in the OU, as well as the management of specific painful conditions. Criteria for referral to observation services relevant to acute musculoskel­etal pain will be reviewed. Other pain-related com­plaints that require specific evaluation and treatment, such as chest pain, abdominal pain, and sickle-cell pain, are discussed elsewhere in this text.
Epidemiology
Painful complaints are frequently treated in the observation setting.
1
In one study, back pain was the sixth most common condition treated in an OU, accounting for 4.7% of patients.
2
Nephro­lithiasis, abdominal pain, pyelonephritis, cellulitis, traumatic injuries, and headache are also painful conditions routinely treated in OUs.
Principles of Pain Management
The treatment of pain is frequently the reason that patients seek medical care, and satisfaction with care has been correlated with effective analgesia.
3
In addition to the relief of suffering, evidence supports the importance of adequate pain mana­gement in the treatment of disease. Unrelieved acute pain has been associated with increased sym­pathetic nervous system activation, decreased immune function, the development of chronic pain, greater need for subsequent pain treatment, and psychosocial dysfunction.
4–6
From a regula­tory standpoint, the Joint Commission mandates documentation of the evaluation and treatment of pain. Clearly, a priority must be placed on the effective treatment of pain in the OU.
Assessment
Accurate assessment of pain is critical to effective management. Inadequate treatment is often due to inaccurate assessment.
7
A patients experience
of pain is dependent on the interaction between the patients physical stimulus, physiology, prior experience and expectation of pain, and their cur­rent emotional and cognitive states. It is known that patients presenting with the same injury will often report widely varying levels of pain.
8
Currently, there are no reliable tests or physiolo­gic measurements to objectively assess a patients level of pain.
9–11
The assessment of pain therefore
remains subjective and unique to each individ­uals experience. To accurately assess pain, it is necessary to consider both verbal and nonverbal communication from the patient, in add ition to objective observations. Accordingly, patients who are unable to communicate effectively are at risk for undertreatment. These groups include chil­dren, patients with a cultural background differ­ent from their provider, patients with mental illness, or patients with emotional or cognitive impairment.
8,12–15
OUs should have a well-defined method for assessing pain. The Joint Commission has man­dated that pain must be assessed using a pain scale as part of routine vital signs. For various develop­mental reasons, numeric pain scales are difficult to use with children <7 years old. Nonnumeric scales can be utilized, such as the FACES pain scale or color-based pain scales, but it is unclear if chil­dren <7 years old, and particularly children <5 years old, can rate pain on a scale. For pre­verbal children, provider-based scales such as Modified Pre-Verbal, Early Verbal Pediatric Pain Scale (M-PEPPS) and the Childrens Hospital of Eastern Ontario Pain Scale (CHEOPS) can be used, but they largely represent a providersjudgmentof how much pain the child is observed to have.
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Medications
Opioid analgesics are the first-line agents for the management of acute severe pain. Opioids acti­vate endorphin system receptors throughout the peripheral and central nervous system to pro­vide analgesia. Potential side effects can include respiratory depression, constipation, nausea and vomiting, urinary retention, and histamine­mediated urticaria and pruritis. However, most patients tolerate opioids well.
A variety of opioid medications are available. Morphine remains commonly used in clinical practice. Hydromorphone is a semisynthetic derivative of morphine that has been associated with less pruritis and nausea than morphine. Eld­erly patients and those with liver disease often tolerate hydromorphone better than morphine because its metabolites are less active and accu­mulate slower than the metabolites of morphine. Fentanyl has a short onset and short duration of action and does not produce active metabolites, but requires frequent monitoring because its asso­ciated incidence of respiratory depression is higher than other opioids, limiting its use in the observation setting. Oxycodone is an effi­ciently absorbed oral agent with a bioavailability approaching 80%, and its effectiveness is compar­able to parenteral therapy.
16
Hydrocodone is a weaker opioid than oxycodone, and is commonly used in combination preparations with acet­aminophen or nonsteroidal anti-inflammatory drugs (NSAIDs). Codeine is a weak opioid that is associated with a high rate of side effects and has little role in the treatment of pain. Tramadol is a weak mu agonist and has some opioid-like properties, but frequently causes nausea and vomiting with increasing doses, limiting its use as a single agent. Table 57.1 lists opioids that are
commonly used and provides an equianalgesic factor using morphine 10 mg as a reference value.
Patients who have been referred to an OU for a painful complaint often have pain that has been refractory to initial treatment, or has required fre­quent dosing that is not amenable to outpatient treatment, therefore, IV administration is often indi­cated. Once pain has been effectively treated and a patients symptoms have stabilized, efforts should be made to transition to oral medications so that an effective regimen can be continued as an outpatient.
Multiple non-opioid medications exist and are appropriate for either first-line or adjunctive treat­ment of pain in combination with opioids. Acet­aminophen is a safe and well-tolerated medication in both children and adults. It can cause hepatic toxicity in the setting of underlying liver disease or concomitant alcohol abuse. Patients with pain who do not have a contraindication should receive acet­aminophen as part of any pain treatment strategy.
NSAIDs such as ibuprofen inhibit cyclooxy­genase, and therefore decrease prostaglandin, resulting in analgesic effects in patients with inflammation. They have a synergistic effect when administered with opioids and acetaminophen and can reduce the amount of opioid needed to treat a painful complaint. Notably, NSAIDs are the cause of more serious drug-related side effects than any other class of analgesic.
18
Side effects include renal failure, gastrointestinal bleeding, platelet dysfunc­tion, and anaphylaxis. NSAIDS should be used cautiously, or not at all, in patients with preexisting renal disease, cardiovascular disease, gastrointest­inal disease, or in pregnant or elderly patients.
Pain Specialists and Pain Clinics
A growing number of physicians are specializing in the practice of pain management, which has been
Table 57.1 Commonly Used Opioid Medications and Their Pharmacokinetic Properties
17
Name Initial Parenteral
Dose
Initial Oral Dose
Duration of Action
Equipotent IV Dose
Equipotent Oral Dose
Morphine 0.1 mg/kg 0.5 mg/kg 3–4 hrs 10 mg 50 mg
Hydromorphone 0.015 mg/kg 0.075 mg/kg 2–4 hrs 1.5 mg 7.5 mg
Fentanyl 1.5 μg/kg 3 μg/kg 30–90 min 100 μg n/a
Oxycodone 0.1 mg/kg 0.15 mg/kg 3–4 hrs 10 mg 15 mg
Hydrocodone n/a 5–15 mg 3–4 hrs n/a 30 mg
Codeine 1.3 mg/kg 2.5 mg/kg 2–4 hrs 130 mg 200 mg
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accompanied by a growth in pain clinics that special­ize in the treatment of pain. Pain specialists often have advanced training in the medical management of acute and chronic pain. Some are trained to per­form procedures such as nerve blocks, steroid injec­tions, or radiofrequency procedures. Depending on local resources, the potential exists for patients being cared for in an OU to engage with these providers. Pain specialists may be available to consult on patients in the OU, or patients can be referred to a pain clinic after discharge. Patients thought to potentiall y benefit from the services of a pain specialist include those with refractory chronic pain, those who have required a large quantity or theprolongeduseofopioids,thosewithanacute exacerbation of chronic pain, patients with chronic pain of malignancy, and people with a chronic or recurrent painful c ondition who may benefit from a specific procedure or treatment regimen from a pain specialist.
19
Special Populations
In general, the principles of pain management for adults are also appropriate to use in a pediatric patient. One of the key differences in the manage­ment of pain in children is that assessment is more difficult, increasing the risk of under appre­ciation and inadequate treatment. It is important for the medical provider to notice both verbal and nonverbal cues in children. Pharmacokinetics of analgesic medications are similar in children, except in neonates and infants, for whom opioid clearance is delayed and plasma levels can be high for a given dose of medication.
The treatment of painful complaints in elderly patientsis complicated by more difficult assessment due to underlying medical conditions, the increased accumulation of breakdown products of medica­tions, and increased sensitivity to side effects. Doses of opioids should be reduced to avoid side effects such as confusion, which occurs much more readily in the elderly. Lastly, NSAID medications are best avoided or used in decreased doses due to their potential to cause renal dysfunction or adverse car­diac events in this age group.
Specific Conditions
While much of the discussion in this chapter can be applied to a variety of painful conditions that are treated in the OU, there are several conditions and scenarios that deserve special mention.
Acute Low Back P ain
Back pain is a common symptom that represents a considerable source of lost productivity for workers and a large amount of health care expend­itures.
20
Though the vast majority of patients pre­senting for an evaluation of acute back pain will be ultimately diagnosed with mechanical or nonspe­cific back pain, several emergent diagnoses must be excluded during the evaluation of this complaint.
While the majority of patients with acute low back pain can be managed as an outpatient, obser­vation may be considered in certain circumstances. For example, if physicians are not able to achieve adequate pain control for a patient with back pain in the emergency department, administration of analgesics can be continued in the observation setting until the pain is controlled sufficiently to permit discharge home. If a neurologic deficit is present and raises concern for serious underlying pathology, a patient could be observed for serial neurologic assessments to assess the progression of the disease and determine the need for additional diagnostic evaluation.
For most patients referred to the OU with low back pain, a careful history and physical examin­ation is sufficient to evaluate their disease state. Plain radiographs have not been found to be useful in the evaluation of uncomplicated back pain of 1–2 months duration.
21
Special attention should be paid to the neurologic and musculo­skeletal examination.
Emergent diagnoses that should be considered include abdominal aortic aneurysm, aortic dissec­tion, cauda equina syndrome, epidural abscess or hematoma,spine fracturewith cord or nerve root compression, meningitis, osteomyelitis, and tumor. If any of these diagnoses are considered, they should be evaluated for appropriately. Patients who have been determined to have a serious and progressive cause of their back pain should typically be treated in an inpatient setting rather than observation. For patients with a significant or progressive neurologic deficit, advanced imaging is often indicated, while noting that advanced imaging for patients with radicular pain and only sensory deficits does not typically change outcome and an initial course of conservative treatment is recommended.
21,22
Medical treatment of acute low back pain should include analgesic medications. Either acet­aminophen or NSAIDs should be prescribed for all patients, unless a contraindication exists. For mod­erate to severe pain, opioids can be considered in
Pain Management, Including Musculoskeletal and Low Back Pain
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addition. Muscle relaxants such as benzodiazepines and cyclobenzaprine may benefit some patients demonstrating muscle spasm on examination, but also can cause serious side effects and should be used with caution.
23
Patients should be encouraged to be as active as their level of pain permits, and should be discouraged from sitting or lying down for prolonged periods of time.
Chronic Pain
The evaluation and treatment of patients with chronic pain is challenging. Patients with chronic pain are considered to be those with a pain com­plaint that has persisted beyond the normal healing of the underlying condition or is not expected to improve with further treatment of the underlying condition. Patients with chronic pain can present with an acute exacerbation of chronic pain, or with untreated/refractory chronic pain. In general, an acute exacerbation of chronic pain can be managed in an OU. There, the patients pain can be stabilized and their previous treatment plan can be resumed. However, inad­equately treated chronic pain should be referred to a primary care provider to develop an outpatient care plan. Because patients with chronic pain can exhibit complex maladaptive behaviors associated with their pain, it can be difficult to develop an effective approach to their pain. For OUs with protocol-based treatment plans, this level of deci­sion making is often too complex for what can be effectively accomplished. Making changes in patientschronic pain treatment strategies during an acute exacerbation of pain and over the rela­tively short period of observation is unlikely to provide an effective long-term solution.
Chronic Pain of Malignancy
Chronic pain of malignancy differs from other causes of chronic pain in that it is managed with an approach similar to that used for acute pain. Opioid pain medications are often indicated and associated with improved outcomes and quality of life, in contrast to their use in nonmalignantchronic pain. Patients are commonly prescribed a long­acting opioid medication in addition to a short­acting medication for breakthrough pain.
24
In the OU, opioid medications may be titrated to the desired effect prior to discharge. For a patient with chronic pain of malignancy who is experiencing an acute exacerbation of pain, care must be taken to
evaluate appropriately for a new medical condition causing the pain, and to not assume that the pain is secondary to the underlying oncologic process.
Criteria for Observation
Careful consideration must be given to which patients with painful complaints are appropriate for observation. Generally, patients with musculo­skeletal pain that may be appropriate for observa­tion are those with 1) an underlying cause of the pain for which inpatient care is not appropriate, and 2) who require multiple doses of IV analgesics without adequate pain relief. Conditions that may require surgery such as a fracture and patients with pain secondary to significant medical illness such as cancer are likely to be most appropriate in an inpatient setting rather than an OU. On the other hand, patients with acute musculoskeletal pain responding to oral analgesics are not likely to be considered appropriate for observation services and could be treated as outpatients. Patients with painful complaints who are unable to ambulate or adequately care for themselves secondary to pain may also be good candidates for observation, as they cannot be safely discharged home.
InterQual® criteria are a commonly used set of criteria to determine the appropriateness of a spe­cific level of care. Though InterQual® or another resource can provide a common foundation for institutions to determine which patients should be referred to observation services, local capabil­ities, expertise, and resources ultimately require individual OUs to formulate their own criteria.
One of the first steps in determining the appro­priate level of care for a patient is to consider whether a specific subset of criteria should be applied. For patients with chest pain of a suspected cardiac etiology, for example, the cardiac criteria should be reviewed. If no other set of criteria seems appropriate, then the following criteria under the Pain, severesection may be useful.
To meet InterQual® Severity of Illness criteria for referral to observation services for severe pain, at least one of the following Severity of Illness (SI) criteria should be met.
25
Intractable and unresponsive to 2 doses of
parenteral analgesics within the last 6 hours
Renal calculus or pyelonephritis, suspected
Migraine, intractable and failed outpatient
treatment
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Abdominal pain, unknown etiology
Sickle cell crisis
For discussion of abdominal pain, headache, renal disease, and sickle cell crisis, please see the appro­priate sections elsewhere in this text. (See Chap­ters 35, 42, 48, 56.) Patients must also meet at least one criteria from the Intensity of Service (IS) section to satisfy InterQual® criteria for observa­tion services. Listed next are common criteria by which patients admitted with painful complaints meet criteria for observation services.
IV fluids 100 ml/hr or IV fluids 75 ml/hr and age 65 or history of chronic heart failure or renal failure
At least two doses of IV analgesics or IV antiemetics or IV anxiolytics
Monitoring of neurologic examination at least six times over 24 hours
Monitoring of vital signs every 4 hours
Consideration should also be given as to whether patients are most appropriate for an inpatient level of care, as opposed to observation. The CMS Two-Midnight Rule was implemented in 2014 and has provided some guidance in this area. In brief, if it is expected at the time of admission that the patientslengthofstaywill be at least two midnights or they have another qualifying condition, they should be admitted as aninpatientinmostcircumstances.Insummary, most patients with acute musculoskeletal pain will be deemed appropriate for observation ser­vices based on the frequency and route of anal­gesic medication administration. It is important to note that hospitals are not strictly bound to these criteria, and that by physician review, a patient can be deemed appropriate for observa­tion services even if these criteria are not pre­cisely met. An example of this could be a patient with severe back pain, who is not able to ambu­late due to pain, but is not requiring multiple doses o f IV analgesic pain medication.
Recommendations for Observation Unit Protocols
While protocols used in OUs must take in to consideration local resources and practice patterns, we have several recommendations regarding the evaluation and treatment of pain in OUs.
All OU protocols or standing orders should include a mechanism to assess pain at regular
intervals. The assessment of pain should be performed at least every 4 hours, and often more frequent assessment is indicated.
Assessment of pain should be performed using age and developmentally appropriate tools. This can be addressed by having different protocols for the treatment of pain for different age groups.
The determination of severity of pain should not rely solely on a numeric rating, and should instead take in to account verbal communication with the patient, nonverbal cues, and objective signs as deemed appropriate.
Orders for appropriate pain medications to be given as needed (prn) should be placed. Only one type of opioid per route of administration should be ordered as a prn medication.
Patients receiving opioid medications should also receive acetaminophen and NSAIDS if they are not contraindicated.
The choice of pain medications should be individualized for each patient, therefore, protocols should require medical providers to actively choose which analgesic medications to use in the OU. Contraindications to certain medications, dosing adjustments, the underlying disease process, and multiple other factors must be considered.
Pulse oximetry monitoring should be considered in patients receiving IV opioids.
A complete history and physical examination should be performed for all patients referred for observation services, focusing on evaluating for emergent and life-threatening causes of pain.
Plain radiography and advanced imaging should not be routinely ordered for patients in OUs with uncomplicated back pain, as this information rarely changes care.
Conclusions
The treatment of pain and painful complaints in the OU is dependent on appropriate assessment, frequent reassessment, recognition of any under­lying medical conditions, and individualized treatment. Care should be taken that patients referred for observation meet criteria, which are often dependent on the frequency at which intra­venous analgesic medi cations are administered. OU protocols should include provisions for the regular assessment of pain.
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References
1. Mace SE, Graff L, Mikhail M, et al. A national survey of observation units in the United States. The American Journal of Emergency Medicine. 2003 Nov.;21(7):529–533.
2. Ross M. The use and effectiveness of an emergency department observation unit for elderly patients. Annals of Emergency Medicine. 2003 May;41(5):668–677.
3. Fosnocht DE, Swanson ER, Bossart P. Patient expectations for pain medication delivery.
American Journal of Emergency Medicine. 2001 Sep.;19(5):
399–402.
4. Bayer BM, Brehio RM, Ding XZ, et al. Enhanced susceptibility of the immune system to stress in morphine­tolerant rats. Brain Behav. Immun. 1994 Sep.;8(3): 173–184.
5. Beilin B, Shavit Y, Trabekin E, et al. The effects of postoperative pain management on immune response to surgery. Anesth Analg. 2003 Sep.;97(3): 822–827.
6. Charmandari E, Kino T, Souvatzoglou E, et al. Pediatric stress: hormonal mediators and human development. Horm. Res. 2003;59(4):161–179.
7. Bijur PE, Bérard A, Esses D, et al. Lack of influence of patient self-report of pain intensity on administration of opioids for suspected long­bone fractures. J Pain. 2006 Jun.;7(6):438–444.
8. Miner J, Biros MH, Trainor A, et al. Patient and physician perceptions as risk factors for oligoanalgesia: a prospective observational study of the relief of pain in the emergency department. Acad Emerg Med. 2006 Feb.;13(2):140–146.
9. Marco CA, Plewa MC, Buderer N, et al. Self-reported pain scores in the emergency department: lack of association with vital signs. Acad Emerg Med. 2006 Sep.;13(9):974–979.
10. Bossart P, Fosnocht D. Changes in heart rate do not correlate with changes in pain intensity in emergency department patients. J Emerg Med. 2007.
11. Hobbs G. Assessment,
Measurement, History and Examination. Clinical Pain Management: Acute Pain.
London: Arnold; 2003.
12. Todd K, Ducharme J, Choiniere M. Pain in the emergency department: results of the pain and emergency medicine initiative (PEMI) multicenter study. The Journal of Pain. 2007.
13. Neighbor ML, Honner S, Kohn MA. Factors affecting emergency department opioid administration to severely injured patients. Acad Emerg Med. 2004 Dec.;11(12): 1290–1296.
14. Tamayo-Sarver JH, Hinze SW, Cydulka RK, et al. Racial and ethnic disparities in emergency department analgesic prescription. Am J Public Health. 2003 Dec.;93(12): 2067–2073.
15. Todd KH, Samaroo N, Hoffman JR. Ethnicity as a risk factor for inadequate emergency department analgesia. JAMA. 1993 Feb.;269 (12):1537–1539.
16. Miner JR, Moore J, Gray RO, et al. Oral versus intravenous opioid dosing for the initial treatment of acute musculoskeletal pain in the emergency department. Acad Emerg Med. 2008 Dec.;15 (12):1234–1240.
17. Miner JR, Paris PM, Yealy DM. Chapter 186: Pain Management. In: Marx J, Hockberger R, Walls RM, eds.
Rosens Emergency Medicine­Concepts and Clinical Practice, 7th Ed. Philadelphia, PA:
Mosby. 2010; 2410–2428.
18. Hersh EV, Pinto A, Moore PA. Adverse drug interactions involving common prescription and over-the-counter analgesic agents. Clin Ther. 2007;29 Suppl:2477–2497.
19. Ksionski S. Personal Communication. 2012.
20. Stewart WF, Ricci JA, Chee E, et al. Lost productive time and cost due to common pain conditions in the US workforce. JAMA. 2003 Nov. 12;290(18):2443–2454.
21. Chou R, Qaseem A, Snow V, et al. Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society. Ann Intern Med. 2007. 478–491.
22. Modic MT, Obuchowski NA, Ross JS, et al. Acute low back pain and radiculopathy: MR imaging findings and their prognostic role and effect on outcome. Radiology. 2005 Nov.;237(2):597–604.
23. Van Tulder M, Touray T, Furlan A. Muscle relaxants for
non-specific low back pain. ...
Database Syst Rev. 2003.
24. Fosnocht DE, Swanson ER, Barton ED. Changing attitudes about pain and pain control in emergency medicine. Emerg Med Clin North Am. 2005 May;23(2):297–306.
25. InterQual®. Level of Care Criteria, Acute Care, Adult. 2011th ed. Newton, MA: McKesson Health Solutions, LLC.
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Subpart IVN
Chapter
58
Clinical – Trauma
Trauma
Mark G. Moseley, MD, MHA, FACEP Miles P. Hawley, MD, MBA
Background
Given the high volume of patients with traumatic complaints that present to most emergenc y departments (EDs), this patient population is an excellent potential source of observation unit (OU) patient volume. ED-based OUs have been found to be useful and cost efficient in the man­agement of trauma patients.
1
One of the primary reasons for this fact is that it can be difficult to diagnose all injuries on initial presentation to the ED, and as such, many trauma patients require additional diagnostic tests, repeat examinations, and clinical monitoring. Historically, this has often lead to trauma patients being hospitalized to accomplish these patient management goals and to ensure safe disposition s.
2
With this noted, recent studies have demonstrated the feasibility of managing trauma patients including trauma team activation patients at Level 1 trauma centers (clearly a sicker cohort of trauma patients) in the OU setting with favorable outcomes.
3,4
Trauma patients in the OU can be considered for both diagn ostic and therapeutic end points on an observation protocol. Diagnostically, many blunt trauma patients require extensive imaging evaluation and a period of serial examinations. For penetrating or blunt trauma patients, the observation period can afford an environment closely linked to intensive resources available to reevaluate the patient and quickly intervene if clinical deterioration is observed. Therapeutically, some patients arrive in the OU with a clear diag­nosis (such as rib fractures) and the goal of the observation period is merely to determine whether the patients are able to manage their symptoms in the outpatient setting sufficient to facilitate discharge.
To this end, it is important to define the goals of the observation period. Is it to diagnose a potential occult injury? Is it to monitor for a complication
like vascular compromise or compartment syn­drome? These goals will help define the resources necessary to successfully evaluate and disposition a given patient. This is extremely important in the trauma patient population, as local resources and the trauma status of the hospital the clinician works at may lead to distinctly different patient popula­tions managed. At a high-volume, high-acuity trauma center, the majority of trauma patients in theOUwillhavealreadybeenclearedby the trauma team of life-threatening injury. Further, extensive resources would be available to reevaluate and resuscitate the patients should they deteriorate. At a nontrauma hospital without trauma team backup, the goals, management resources, and the ability to disposition specific patient populations may differ greatly and should be considered in trauma protocol design.
Patient Selection – Inclusions
Inclusion criteria will vary based on local resources and the capabilities of the OU and its provider team. As noted earlier, there will be variation in the capabilities based on the facility where the clinician works (trauma center or not). While a general observation protocol for trauma can be a catchall for multiple conditions, specific protocols for specific conditions may be con­sidered separately and have distinct criteria. For higher-volume protocols of this subset such as closed head injury, this is prudent since the needs of these patients will differ from patients with more extensive blunt or penetrating trauma. Whether to include pediatric patients, and the age that defines a pediatric patient, will also be an important consideration based on institution and provider preferences. One other important consideration for patient placement is the com­fort level of the providers with managing trauma patients. Physicians that are routinely managing
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trauma patients should be board certified in emer­gency medicine, trauma surgery, or other appro­priate surgical specialty with trauma experience or well versed in Advanced Trauma Life Support (ATLS) or its equivalent. Nurses routinely caring for trauma patients should be certified emergency nurses or well versed in a nursing equivalent of ATLS. This should ensure appropriate know­ledge, aptitude, and skill sets in managing trauma patients.
Patient Selection – Exclusions
In the trauma patient population, intoxication and altered mental status are clearly a challenge for appropriate patient selection.
5
Some units and protocols have specific blood alcohol cutoffs, while others prefer to select based upon the per­ception of clinical sobriety or patients who are directable and compliant with therapy rather than a specific number on the patients blood alcohol level (BAL). Care should be taken to ensure that violent, belligerent, and nonparticipatory patients with intoxicants on board are not placed in the OU. Setting a Glasgow Coma Scale (GCS) of <14 as an exclusion criteria can assist to this end and also appropriately risk stratify for mild head injury patients. Other exclusion criteria would include hemodynamically unstable patients, patients receiving blood products or aggressive fluid resuscitation, major burn patients, or patients who inevitably need surgical management. Any patient that meets criteria for a transfer to a higher-level trauma center based on ATLS should be excluded at a nontrauma facility.
Pathophysiology
Numerous traumatic conditions are amenable to observation protocols in the OU. As noted earlier, local resources will dictate which protocol popula­tions can be targeted and created based on the demographics and capabilities of the facility where the OU is located. What follows is a listing of some commonly managed traumatic conditions.
Motor Vehicle Collisions
Blunt trauma can be challenging both diagnostically and therapeutically. Occult injuries can be difficult to uncover after initial ED evaluation. As such, patients with blunt trauma from motor vehicle col­lisions (MVC) are an excellent population to target
for an OU protocol. Benefits of the observation period include the ability to do serial examinations, obtain final readings on imaging studies (which can be significant in this population), monitor the patients ability to control his or her symptoms, and discharge the patient with a lower risk for significant injury misses.
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Issues in management for this patient popu­lation can include dealing with cervical spine clearance, such as a protocol for who clears the patients c-spine, when it is important or neces­sary to establish c-spine clearance, and the cri­teria for c-spine clearance in significantly injured MVC patients. The occurrence of closed head injury (or concerns sufficient to warrant obser­vation for same) in the MVC population pro­vides adequate justification in most instances to observe a patient and obtain frequent neurologic checks (particularly if imaging is withheld in favor of clinical monitoring).
Patients experiencing more significant blunt trauma from MVC often benefit from serial examinations even if imaging is negative. Repeat Focused Assessment by Sonography for Trauma (FAST) examinations are also recommended.
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Pain and symptom control, intravenous (IV) fluids, and the ability to ambulate and tolerate oral intake are important for disposition consid­erations in this patient population.
Rib Fractures
Patients with isolated or in some cases even mul­tiple rib fractures are candidates for a trauma protocol with therapeutic end points. Safety, effi­cacy, and cost-effectiveness of managing these patients has been previously studied.
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The goals of the observation period are primarily to deter­mine if the patient can tolerate his or her pain and symptoms assuming life-threatening traumatic injury has been excluded. The focus of the obser­vation period can be therapeutic in terms of pro­viding analgesia and relief from pain as well as a focus on pulmonary toilet. A subset of patients with thoracic trauma has a concern for cardiac or myocardial contusion. In this patient population, cardiac monitoring, serial cardiac enzymes, and even echocardiography are sometimes considered in patient management and disposition decisions and can clearly be accomplished in the OU setting (although the precise workup diagnostically for these patients is still controversial).
Mark G. Moseley and Miles P. Hawley
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