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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_3695_Библиотеки_им_академика_М_И_Перельмана
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CONTENTS
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Case 1357. Theleman KP, Grayburn PA, Roberts WC. Mitral “Annular”
Calcium Forming a Complete Circle “O” Causing Mitral Stenosis
in Association with a Stenotic Congenitally Bicuspid Aortic
Valve and Severe Coronary Artery Disease. Am J Geriatr Cardiol.
20 0 6;15(1):58 – 61
Case 1359. Sims JB, Roberts BJ, Roberts WC, Hebeler RF Jr, Grayburn PA. The
Heaviest Known Operatively-Excised Aortic Valve. Am J Cardiol.
2006;97(4):588–589
Case 1361. Peterman MA, Donsky MS, Matter GJ, Roberts WC. A Starr-
Edwards Model 6120 Mechanical Prosthesis in the Mitral Valve
Position for 38 Years. Am J Cardiol. 2006;97(5):756–758
Case 1374. Roberts WC, Grayburn PA. Sudden Onset of “Cardiac”
Symptoms, (?) Mild or Severe Aortic Valve Stenosis Involving a
Congenitally Bicuspid Aortic Valve, and Nearly Normal Coronary
Arteries in an Octogenarian. Am J Geriatr Cardiol. 2006;15(3):185–187
Case 1390. Roberts WC, Ko JM, Matter GJ. Isolated Aortic Valve Replacement
Without Coronary Bypass for Aortic Valve Stenosis Involving
a Congenitally Bicuspid Aortic Valve in a Nonagenarian. Am J
Geriatr Cardiol. 2006;15(6):389–391
Case 1423. Roberts WC, Ko JM, Schussler JM. Sudden Collapse in Aortic
Stenosis. Am J Geriatr Cardiol. 2007;16(5):319–320
Case 1445. Gibbs WN, Hamman BL, Roberts WC, Schussler JM. Diagnosis of
Congenital Unicuspid Aortic Valve by 64-Slice Cardiac Computed
Tomography. Proc Bayl Univ Med Cent. 2008;21(2):139
Case 1502. Roberts WC, Velasco CE, Ko JM, Matter GJ. Comparison of the
Quantity of Calcic Deposits in Bovine Pericardial Bioprostheses
in the Mitral and Aortic Valve Positions in the Same Patient
Late After Double-Valve Replacement. J Thorac Cardiovasc Surg.
2009;138(6):1448 –1450
Case 1506. Roberts WC, Ko JM, Schumacher JR, Henry AC III. Combined
Mitral and Aortic Stenosis of Rheumatic Origin with
Double-Valve Replacement in an Octogenarian. Int J Cardiol.
2010;140(1):e1–e3
Case 1531. Roberts WC, Varughese CA, Ko JM, Grayburn PA, Hebeler RF
Jr, Burton EC. Carcinoid Heart Disease Without the Carcinoid
Syndrome but with Quadrivalvular Regurgitation and
Unsuccessful Operative Intervention. Am J Cardiol.
2011;107(5):788–792
Case 1559. Head SJ, Ko J, Singh R, Roberts WC, Mack MJ. 43.3-Year
Durability of a Smeloff-Cutter Ball-Caged Mitral Valve. Ann
Thorac Surg. 2011;91(2):606–608
Case 1589. Roberts WC, Zafar S, Ko JM, Carry MM, Hebeler RF. Combined
Congenitally Bicuspid Aortic Valve and Mitral Valve Prolapse
Causing Pure Regurgitation. Proc Bayl Univ Med Cent.
2013;26(1):30–32
Case 1611. Sarmast S, Schussler JM, Ko JM, Roberts WC. Infective
Endocarditis Superimposed on a Massively Calcied Severely
Stenotic Congenitally Bicuspid Aortic Valve. Proc Bayl Univ Med
Cent. 2014;27(1):37– 38
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 212
. . . . . . . . . . . . . . 215
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223
. . . . . . . . . . . . . . . . . . 226
. . . . . . . . . . . . . . 229
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 235
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 240
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 252
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 256
. . . 219
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CONTENTS
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Case 1636. Roberts CC, Parmar RJ, Grayburn PA, Patankar GR, Ko JM,
Hamman BL, Roberts WC. Clues to Diagnosing Carcinoid Heart
Disease as the Cause of Isolated Right-Sided Heart Failure. Am J
Cardiol. 2014;114(10):1623–1626
Case 1723. Fathima S, Hall SA, Grayburn PA, Roberts WC. The Mitral Valve
16 Months After Operative Insertion of the Aleri Stitch. Am J
Cardiol. 2019;123(4):695–696
Case 1727. Thakkar SJ, Grayburn PA, Hall SA, Roberts WC. Orthotopic Heart
Transplantation for Ankylosing Spondylitis Masquerading as
Nonischemic Cardiomyopathy. Am J Cardiol. 2019;123(10):1732–1735
Case 1729. Roberts WC, Grayburn PA, Lander SR, Meyer DM, Hall SA. Effect
of Progressive Left Ventricular Dilatation on Degree of Mitral
Regurgitation Secondary to Mitral Valve Prolapse. Am J Cardiol.
2019;123(11):1887–1888
Case 1733. Roberts WC, Lee AY, Lander SR, Roberts CS, Hamman BL.
Libman-Sacks Endocarditis Involving a Bioprosthesis in the
Aortic Valve Position in Systemic Lupus Erythematosus. Am J
Cardiol. 2019;124(2):316–318
Case 1735. Chalkley RA, Kim CW, Choi JW, Roberts WC, Schussler JM.
Smeloff-Cutter Mechanical Prosthesis in the Aortic Position for 49
Years. Am J Cardiol. 2019;124(3):457–459
Case 1740. Roberts WC, Siddiquiz S, Rafael-Yarihuaman AE, Roberts CS.
Management of Adults with Normally Functioning Congenitally
Bicuspid Aortic Valves and Dilated Ascending Aortas. Am J
Cardiol. 2020;125(1):157–160
Case 1753. Ather N, Roberts WC. Cardiovascular Ochronosis. Cardiovasc
Pathol. 2020;48:107219
Case 1760. Roberts WC, Kapoor D, Main ML. Virtually All Complications of
Active Infective Endocarditis Occurring in a Single Patient.
Am J Cardiol. 2020;137:127–129
Case 1763. Sovic WR, Ngo Q, Patlolla S, Guileyardo JM, Roberts WC. Isolated
Mitral Valve Endocarditis with Ring Abscess and Pericarditis in
End-Stage Renal Disease. Proc Bayl Univ Med Cent. 2021; 34:
403–404
Case 1780. Makhdumi M, Meyer DM, Roberts WC. Malignancy-Associated
Non-Bacterial Thrombotic Endocarditis Causing Aortic
Regurgitation and Leading to Aortic Valve Replacement.
Am J Cardiol. 2021;154:120–122
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 295
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 266
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279
. . . . . . . . . . . . . . . . . . . . . . . . . . 284
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 288
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 305
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 312
. . 270
Index
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317
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Preface
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When these case reports (numbering 272) were sent to the publisher my intention
was that all would be published in one or two volumes. The publisher, however,
convinced me that the collection of case reports would be too large if they were all
published together, and that decision resulted into dividing the collection into six
smaller books arranged by subject. Ind case reports useful and often they are the
rst publication of many authors. William Osler published many case reports in
the later decades of the 19th century. Today, the JACC has a journal devoted solely
to case reports. The doctor-patient relationship is one on one. Most journals today
publish case reports, but their name is usually disguised as something else.
William C. Roberts, MD
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About the Editor
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William C. Roberts, MD, was born in Atlanta,
Georgia, on September 11, 1932. He graduated
from Southern Methodist University (1954)
and Emory University School of Medicine
(1958). He did his training in internal medicine
at the Boston City Hospital and at The Johns
Hopkins Hospital. He had a 1-year fellowship
in cardiology at the National Heart, Lung and
Blood Institute. He did his training in anatomic
pathology at the National Institutes of Health
(1959-1962). From July1964 to March1993, he was
Chief of Pathology in the National Heart, Lung,
and Blood Institute, National Institutes of Health,
Bethesda, Maryland. He has written 1784 articles.
Additionally, he has edited 31 books and lectured
in more than 2200 cities around the world.
From December 1992 through December2018,
Dr. Roberts was program director of the Williamsburg Conference on Heart
Disease held every December in Williamsburg, Virginia. The American College of
Cardiology Foundation sponsored this conference for 30years. Since March 1993,
Dr. Roberts had been the executive director of the Baylor Heart and Vascular Institute
at Baylor University Medical Center in Dallas, Texas. He served as the editor in chief
of the Baylor University Medical Center Proceedings from 1994 to 2022 (29years) and
the editor in chief of The American Journal of Cardiology from June1982 until July2022
(40years).
He received many honors, including the 1978 Gifted Teacher Award from The
American College of Cardiology; the 1983 College Medalist Award of the American
College of Chest Physicians; the Public Health Service Commendation Medal in
1979; the 1984 Richard and Hilda Rosenthal Foundation Award from the Council
of Cardiology of the American Heart Association; an honorary Doctor of Science
degree from Far Eastern University, Manila, Philippines in 1995; the designation of
Master from The American College of Cardiology in 2004; the Lifetime Achievement
Award of The American College of Cardiology in 2016; and the Lifeti me Achievement
Award for D’s CEO’s Excellence in Healthcare Awards in 2021.
Sadly, Dr. William C. Roberts passed away in June 2023 at the age of 90, just as
this book series went into production.
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Introduction
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Case reports have had a long history. Many diseases have been reported initially as a
case report. The rst publication of many authors, including the present author, was
a case report. William Osler’s curriculum vitae (CV) is loaded with individual case
studies on a variety of conditions. Paul Dudley White’s CV, particularly his early
publications, is loaded with individual case reports. Indeed, he indicated that he
tried to write a case report on a variety of cardiovascular conditions to familiarize
himself quickly with them.
The physician-patient relationship is a one-on-one encounter. Although
randomized clinical trials are favored today, often it is difcult to t a single patient
into these types of studies due to the heterogeneous nature of the populations. Some
patients or circumstances cannot be described except in the case-report format. An
example might be case #342 included in volume 6, which described a man who
was shot; the bullet coursed through the right atrium and then through the right
ventricular outow tract, preventing ow to the left side of the heart. Autopsy
disclosed the left atrial appendage to have protruded through the mitral orice,
suggesting that the left ventricle had a negative pressure during ventricular diastole,
something conrmed physiologically in a subsequent publication. We recently
received a manuscript describing a young boy who was thrown from his vehicle
and landed on a rattlesnake who bit him on his leg that was the site of a compound
fracture suffered during the accident. The case-report format is the only mechanism
to report such events.
Many disease entities have been described initially as case reports: Ochronosis
by Rudolph Virchow (1821–1920), sickle-cell anemia by James B. Herrick (1861–1954),
and the Pickwickian syndrome (obesity-hyperventilation syndrome) by Charles
Sydney Burwell (1893–1967) are just a few examples. Multiple rst operations were
described initially in the case report format, as well as the rst effective anesthetic
drug.
Another benet of case reports is that they provide the opportunity for young
physicians to break into the medical publishing arena. They can be used to describe
a new facet of a disease or provide a fuller description of an entity described
previously. New journals often begin by publishing case reports. (See the early
issues of the Mayo Clinic Proceedings or the Cleveland Clinic Medical Quarterly or the
Baylor University Medical Center Proceedings.)
Some authors, editors, and readers minimize the usefulness of case reports
to medical education. We recently received a case report from an important and
established investigator who indicated that he was really not in favor of publishing
case reports but that his was “special” and deserved rapid acceptance and
publication. This type of comment is fairly frequent.
In more modern times, several collections of case reports have been published.
The New England Journal of Medicine calls them “Images in Clinical Medicine” or
“Case Records of the Massachusetts General Hospital”; The Lancet calls them
“Clinical Picture”; Circulation calls them “Cardiovascular Images” or “Cases and
Traces” or “ECG Challenge”; JAMA Cardiology calls them “JAMA Cardiology
Clinical Challenge”; and The American Journal of Medicine calls them “Diagnostic
Dilemma” or “Images in Dermatology” or “Images in Radiology” or “ECG Image of
the Month,” to name a few examples. The Journal of the American College of Cardiology
has an entire journal devoted to case reports (JACC Case Reports).
The present collection of case reports, of course, is not the rst. An early
collection of case studies was by Ambroise Pare called Oeuvres in 1628 (in French)
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INTRODUCTION
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and compiled and edited by Wallace B. Hamby and titled The Case Reports and
Autopsy Records of Ambroise Pare (in English) in 1960. These short descriptions of
patients are fascinating and enjoyable reading. Richard C. Cabot, who started the
clinicopathologic conferences at the Massachusetts General Hospital, published
Case Teaching in Medicine—A Series of Graduated Exercises in the Differential Diagnosis,
Prognosis and Treatment of Actual Cases of Disease in 1906. Cabot described 78 patients,
most of whom went to autopsy and some to surgery. The collection included patients
with a variety of conditions. Cabot’s 1906 book led to “The Case History Series”: Case
Histories in Pediatrics by John Lovett Morse; Surgical Problems by James G. Mumford
in 1911 (100 cases); and Case Histories in Neurology by E. W. Taylor in 1911.
In more modern times, several collections of case reports have been published.
The most popular are under the general heading of Clinicopathologic Conferences
of The Massachusetts General Hospital: the collection of cases, published individual
books, are variously titled Selected Medical Cases; Surgical; Bone and Joint; Neurologic;
and Cardiac. The latter by Benjamin Castleman and Roman W. De Sanctis presents
50 cases of various cardiovascular diseases studied both clinically and at necropsy.
(The gross photos of the hearts cannot be recommended.)
Finally, case reports are fun reading (particularly Ambroise Pare’s Selections).
They are a “break” from the data-heavy multicenter placebo-controlled trials and
metaanalyses.
When these 272 case reports were sent to the publisher, my intention was that
all would be published in one or two volumes. The publisher, however, convinced
me that the collection of case reports would be too large if they were all published
together, and that decision resulted into dividing the collection into six smaller
books arranged by subject:
1. Congenital Heart Disease
2. Valvular Heart Disease
3. Coronary Heart Disease and Hyperlipidemia
4. Cardiomyopathy
5. Cardiac Neoplasm
6. Cardiovascular Diseases with a Focus on Aorta
The case reports were written by me and colleagues over a 61-year period (1961
to 2022). All 272 describe a single patient with a cardiovascular disease, nearly
all of whom were studied both clinically and morphologically, i.e., at autopsy or
after cardiac transplantation or after another cardiovascular operation. Thus, the
collection is unique. Each report is numbered as it appears in my CV, which includes
as of August15, 2022, a total of 1784 publications (Table 1). Some were book chapters,
published interviews of prominent physicians, or published symposia in which
Iparticipated, but most (952) were patient-centered studies.
Disclaimer:
All case reports are reprinted exactly as rst published.
xviii
William C. Roberts, MD
May5, 2022

IntroduCtIon
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Table 1: Number and types of articles published by William C.
Roberts, MD, 1961–2022
Article type N
1. Patient-centered studies 952
a. Single patient 269
b. Multipatient 666
c. Nonpatient 17
2. From-the-editor columns 342
a.
AJC (1982–2022) 234
b. BUMC (1994–2021) 108
3. Other editorials, mini reviews, forewords, historical
pieces (all journals) 67
4. Chapters in books 143
5. Interviews 197
a. AJC 77
b. BUMC 96
c. Visiting professors 24
6. Published symposia (“AJC editor’s roundtable”) 43
7. AJC in month (25years earlier)
(May1983–August1988) 40
Total 1784
AJC indicates American Journal of Cardiology;
BUMC, Baylor University Medical Center Proceedings.
Note: Additional publications were added after this table was compiled,
including additional case studies, with a new total of 272.
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