Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_4455_Библиотеки_им_академика_М_И_Перельмана

Hydrocephalus is another disorder that should be mentioned. Third, fourth, and lateral ventricle hydrocephalus can easily compromise the CANS due the close proximity of these ventricles to central auditory nuclei and tracts (Mus­iek et al., 1994). Leukodystrophies are a category of degenerative disorders often inherited that can result in myelin dam­age. The auditory evoked potentials often are abnormal in this category of disease (De Meirleir, Taylor, & Logan, 1988). More recently, Bamiou and colleagues (2007) have shown auditory interhemispheric processing difficulties in children with congenital aniridia due to PAX6 genetic mutations. Auditory deprivation from long-standing peripheral hearing loss is another condition that can result in cen­tral auditory deficits. Auditory halluci­nations associated with schizophrenia have garnered much interest in certain audiology circles. This is likely happen­ing because emerging data has shown that some patients with schizophrenia (i.e., those who experience auditory hal­lucinations) are demonstrating changes in the auditory cortex (reduced volumes) and decreased performance on central auditory tests (see Musiek et al., 2007). In the early 1980s, Morest (1983) profiled research in animals with peripheral hear­ing deficits that demonstrated trans-syn­aptic degeneration of auditory neurons and altered cortical organization due to a lack of auditory stimulation in these animals. This research has since been well accepted and expanded upon and has major implications across a variety of disorders, consistent with the concept of reduced neural connectivity that was discussed earlier. The foregoing disorders are some of the additional types of cen­tral nervous system compromise that can affect the central auditory structures. As