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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5330_Библиотеки_им_академика_М_И_Перельмана

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Contents
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xi
Market Overview of Herbal Medicines for Lifestyle Diseases . . . . . . . . . . . . . . . . . . . . 597
Bedanta Bhattacharjee, K. Sandhanam, Shatabdi Ghose, Dhunusmita Barman, and Ram Kumar Sahu
Future Prospective of Herbal Medicines for Lifestyle Diseases . . . . . . . . . . . . . . . . . . . 615
Lolita Rapoliene and Vilma Matuleviciute
Editors and Contributors
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About the Editors
AmalKumarDhara, PhD has over 25years of teaching and research experience in the eld of Pharmacology and Toxicology, especially in the eld of neuropharmacology, anti-inammatory, antiulcer, free radical scav­enging activities of Indian indigenous plants. He has earned his PhD in Pharmaceutical Sciences from Jadavpur University, Kolkata, West Bengal, India. Currently, Dr. Dhara is working as a Lecturer in Pharmacy at Contai Polytechnic, Govt. of West Bengal, India. Dr. Dhara has also served as Production Executive at M/S Deys Medical Stores Mfg (UP) Ltd., U.P., India, for more than 3years. To date, he has authored over 10 research and review publications in various high-impact peer-reviewed journals, 14 book chapters, and 4 books to his credit. Dr. Dhara has participated and presented his research work at several conferences in India and abroad. He is a life member of the Indian Pharmaceutical Association, Indian Pharmacological Society, and is a Registered Pharmacist.
SubhashC.Mandal, PhD is a Professor at the Division of Pharmacognosy, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. Professor Mandal is the recipient of prestigious awards including Endeavour Research Award, Government of Australia; Distinguished Education & Research Award, American Association of Indian Pharmaceutical Scientists (AAiPS), United States; Talented Scientist Award, University of Colombo, Sri Lanka; SAARC Fellowship Award, University Grants Commission (UGC), Bangladesh; Fast Track Young Scientist Award, Department of Science and Technology, UGC Research Award, India; and Outstanding University Teachers’ Award, Department of Higher Education, Government of West Bengal, India. He has supervised more than 30 doctoral and 25M.Pharm scholars and has more than 300 research publications, several patents, books, and book chapters to his credit. Professor Mandal has delivered more than 50 research presentations around the globe, has chaired many international conferences, and success­fully completed more than 10 government-funded research projects. He is a reviewer and board member of several high-impact journals and is a recognized host scientist for many international research programmes with developing countries sponsored by the Government of India. He has visited more than 30 countries for various scientic deliberations, collaborations, and exchange programmes.
Contributors
Md Abubakar Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Guwahati, Guwahati, Assam, India
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Hajipur, Hajipur, Bihar, India
Niyati Acharya Department of Pharmacognosy, Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, India
Priyanka Adhikari Center for GMP Extraction Facility (Department of Biotechnology), National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
School of Medicine, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA
BrunoDuponA.Ambamba Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon
xiii
xiv
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VahidRezaAskari International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
ArunBaidya Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
SparshaBandekar Satara College of Pharmacy, Satara, Maharashtra, India
Sugato Banerjee Department of Pharmacology and Toxicology, National Institute of
Pharmaceutical Education and Research, Kolkata, India
TanmoyBanerjee Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
JagdishS. Bankar Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
Dhunusmita Barman Department of Pharmacology, NEF College of Pharmaceutical Education and Research, Nagaon, Assam, India
SouvikBasak Dr. B.C. Roy College of Pharmacy and AHS, Durgapur, India
Ashok Behera Faculty of Pharmacy, School of Pharmaceutical and Populations Health
Informatics, DIT University, Dehradun, India
Samir Bhargava Faculty of Pharmacy, School of Pharmaceutical and Populations Health Informatics, DIT University, Dehradun, India
Editors and Contributors
BedantaBhattacharjee Department of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Tezpur, Assam, India
Bhavna Faculty of Pharmacy, School of Pharmaceutical and Populations Health Informatics, DIT University, Dehradun, India
Surbhi S. Bhope Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
Kajal N. Bondre Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
RituparnaChaki Dr. B.C.Roy College of Pharmacy and Allied Health Sciences, Durgapur, India
MoumitaChatterjee V.Sivaram Research Foundation, Bangalore, Karnataka, India
Sunayna Choudhary Department of Pharmacognosy, M.M. College of Pharmacy, M.M.
(Deemed to be University), Mullana, Ambala, Haryana, India
Anchal Dabas Department of Applied Chemistry, Delhi Technological University, Delhi, India
ZoraDajić Faculty of Agriculture, University of Belgrade, Belgrade, Serbia
S.Dangat Department of Pharmacognosy and Phytochemistry, Bombay College of Pharmacy,
Mumbai, Maharashtra, India
Anish Kumar Das Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER) - Kolkata, Kolkata, West Bengal, India
Amal Kumar Dhara Department of Pharmacy, Contai Polytechnic, Government of West Bengal, Contai, West Bengal, India
AmitKumarDixit Central Council for Research in Ayurvedic Sciences (CCRAS)-Central Ayurveda Research Institute, Ministry of Ayush, Govt. of India, Kolkata, West Bengal, India
Editors and Contributors
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xv
Amit Kr. Dubey Faculty of Pharmacy, School of Pharmaceutical and Populations Health Informatics, DIT University, Dehradun, India
Subhajit Dutta Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
Ronin Institute for Independent Scholarship, Montclair, NJ, USA
Sharmistha Ganguly University Department of Botany, Ranchi University, Ranchi, Jharkhand, India
Geetanjali Department of Chemistry, Kirori Mal College, University of Delhi, Delhi, India
ShatabdiGhose Department of Pharmacology, Guwahati, Assam, India
MadhurimaGhosh Department of Pathology and Cancer Screening, Chittaranjan National
Cancer Institute, Kolkata, India
NilanjanGhosh Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
Shailendra S. Gurav Department of Pharmacognosy, Goa College of Pharmacy, Goa University, Panaji, Goa, India
AmitKumarHalder Dr. B.C. Roy College of Pharmacy and Allied Health Sciences, Dr. Meghnad Saha Sarani, Bidhannagar, Durgapur, West Bengal, India
Md Saquib Hasnain Department of Pharmacy, Palamau Institute of Pharmacy, Chianki, Daltonganj, Jharkhand, India
PrakashR.Itankar Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
SiddhiJain Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
Donald Ulrich K. Kagho Department of Chemistry, Higher Teacher Training College, University of Yaoundé I, Yaoundé, Cameroon
Sanmoy Karmakar Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
Ceyda Sibel Kılıç Faculty of Pharmacy, Department of Pharmaceutical Botany, Ankara University, Ankara, Turkey
SimeonF.Kouam Department of Chemistry, Higher Teacher Training College, University of Yaoundé I, Yaoundé, Cameroon
Ankit Kumar Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
J.Kumar University Department of Botany, Ranchi University, Ranchi, Jharkhand, India
K.JayaramKumar Department of Pharmaceutical Sciences and Technology, Birla Institute
of Technology, Mesra, Ranchi, Jharkhand, India
SonaliMaheshwari Institute of Pharmacy, Nirma University, Ahmedabad, India
JaiMalik Department of Pharmacognosy, University Institute of Pharmaceutical Sciences—
UGC Centre of Advanced Study, Panjab University, Chandigarh, India
Keya Mallick Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Kolkata, India
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Subhash C. Mandal Department of Pharmacognosy and Phytochemistry, Shri Vile ParleKelavani Mandal’s Institute of Pharmacy, Dhule, Maharashtra, India
Pharmacognosy and Phytochemistry Research Laboratory, Division of Pharmacognosy, Department of Pharmaceutical Technology, Faculty of Engineering & Technology, Jadhavpur University, Kolkata, India
Department of Pharmacognosy, K.L.E.’s College of Pharmacy, Nehru Nagar, Belagavi, Karnataka, India
VilmaMatuleviciute Klaipėda University, Klaipeda, Lithuania
The Excelsior School of Herbal Medicine, Belfast, Northern Ireland
MilanMilivojević Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia
JayashreeMondal Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
TitusAlfredM.Msagati Institute for Nanotechnology and Water Sustainability, College of Science, Engineering and Technology, University of South Africa, Florida Science Campus, Johannesburg, South Africa
A.Mukne Department of Pharmacognosy and Phytochemistry, Bombay College of Pharmacy, Mumbai, Maharashtra, India
Editors and Contributors
V. G. M. Naidu Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
Center for GMP Extraction Facility (Department of Biotechnology), National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
ParvathyG.Nair CCRAS-National Research Institute for Panchakarma, Ministry of Ayush, Govt. of India, Thrissur, Kerala, India
PratibhaP.Nair VPSV Ayurveda College, Kottakal, Kerala, India
Ajay G. Namdeo Department of Pharmaceutical Sciences, Hemvati Nandan Bahuguna
Garhwal University (A Central University), Srinagar, Uttarakhand, India
Satheesh Kumar Nanjappan Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER) - Kolkata, Kolkata, West Bengal, India
Vilas D. Nasare Department of Pathology and Cancer Screening, Chittaranjan National Cancer Institute, Kolkata, India
AnujNautiyal Department of Pharmacy, SGRR University, Dehradun, India
Amit Kumar Nayak Department of Pharmaceutics, School of Pharmaceutical Sciences,
Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
BathelemyNgameni Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
YvanAndersonT.Ngandjui Department of Chemistry, Higher Teacher Training College, University of Yaoundé I, Yaoundé, Cameroon
Institute for Nanotechnology and Water Sustainability, College of Science, Engineering and Technology, University of South Africa, Florida Science Campus, Johannesburg, South Africa
Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon
Editors and Contributors
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xvii
SundayOritsetimenyinOtimenyin Department of Pharmacology, Faculty of Pharmaceutical Sciences, University of Jos, Jos, Nigeria
Ivana Pajic-Lijaković Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia
Samir Ranjan Panda Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
Jayesh S. Pande Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
Shweta Parihar Department of Pharmacognosy, University Institute of Pharmaceutical Sciences—UGC Centre of Advanced Study, Panjab University, Chandigarh, India
A.Parthiban Center for GMP Extraction Facility (Department of Biotechnology), National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
KalpanaPatil Department of Pharmacognosy and Phytochemistry, Shri Vile Parle Kelavani Mandal’s Institute of Pharmacy, Dhule, Maharashtra, India
Pharmacognosy and Phytochemistry Research Laboratory, Division of Pharmacognosy, Department of Pharmaceutical Technology, Faculty of Engineering & Technology, Jadhavpur University, Kolkata, India
Department of Pharmacognosy, K.L.E.’s College of Pharmacy, Nehru Nagar, Belagavi, Karnataka, India
Tiyasa Paul Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India
Arun N. Prakash Department of Pharmacology and Toxicology, National Institute of Pharmaceutical and Research (NIPER)-Guwahati, Guwahati, Assam, India
AabirPramanik Institute of Pharmacy, Nirma University, Ahmedabad, India
Neethu Prasad Department of Pharmacology and Toxicology, National Institute of
Pharmaceutical and Research (NIPER)-Guwahati, Guwahati, Assam, India
SatyendraK.Prasad Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
Eswara Rao Puppala School of Medicine, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA
MohamedRahamathulla Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi Arabia
Vafa Baradaran Rahimi Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
VimalavathiniRamesh Department of Pharmacology, College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences, Puducherry, India
VijaySingh Rana Faculty of Pharmacy, School of Pharmaceutical and Populations Health Informatics, DIT University, Dehradun, India
AlokRanjan Center for GMP Extraction Facility (Department of Biotechnology), National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
LolitaRapoliene Klaipėda University, Klaipeda, Lithuania
Baltic Medics Port Clinic, Klaipeda, Lithuania
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SaptapadiSaha Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
Ram Kumar Sahu Department of Pharmaceutical Sciences, Hemvati Nandan Bahuguna Garhwal University (A Central University), Chauras Campus, Tehri Garhwal, Uttarakhand, India
K.Sandhanam Department of Pharmacology, SRM College of Pharmacy, SRM Institute of Science and Technology, Chengalpattu, Tamil Nadu, India
ShuvamSar Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
Arnab Sarkar Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India
SathiSarkar Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER) - Kolkata, Kolkata, West Bengal, India
K.Sawate Department of Pharmacognosy and Phytochemistry, Bombay College of Pharmacy, Mumbai, Maharashtra, India
NeerajKr.Sethiya Faculty of Pharmacy, School of Pharmaceutical and Populations Health Informatics, DIT University, Dehradun, India
Satish Shilpi Faculty of Pharmacy, School of Pharmaceutical and Populations Health Informatics, DIT University, Dehradun, India
Editors and Contributors
P. Shirodkar Department of Pharmacognosy and Phytochemistry, Bombay College of Pharmacy, Mumbai, Maharashtra, India
Meenakshi Singh Centre for GMP Extraction Facility, Sponsored by Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER)­Guwahati, Guwahati, Assam, India
RamSingh Department of Applied Chemistry, Delhi Technological University, Delhi, India
ManmohanSinghal Faculty of Pharmacy, School of Pharmaceutical and Populations Health
Informatics, DIT University, Dehradun, India
SarojSinghmura Dr. B.C. Roy College of Pharmacy and AHS, Durgapur, India
Kayalvizhie Subbarayan Department of Pharmacology, College of Pharmacy, Mother
Theresa Post Graduate and Research Institute of Health Sciences, Puducherry, India
Kavimani Subramanian Department of Pharmacology, College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences, Puducherry, India
N. P. Syamprasad Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, Assam, India
Rostan M. Talla Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon
Joseph Tchamgoue Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon
Department of Chemistry, Higher Teacher Training College, University of Yaoundé I, Yaoundé, Cameroon
JeanClaudeTchouankeu Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon
Editors and Contributors
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Sittarthan Viswanathan Department of Pharmacology, College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences, Puducherry, India
RajuWadekar Department of Pharmacognosy and Phytochemistry, Shri Vile ParleKelavani Mandal’s Institute of Pharmacy, Dhule, Maharashtra, India
Pharmacognosy and Phytochemistry Research Laboratory, Division of Pharmacognosy, Department of Pharmaceutical Technology, Faculty of Engineering & Technology, Jadhavpur University, Kolkata, India
Department of Pharmacognosy, K.L.E.’s College of Pharmacy, Nehru Nagar, Belagavi, Karnataka, India
PratikshaP.Wagh Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India
ParulYadav Department of Applied Chemistry, Delhi Technological University, Delhi, India
Introduction toLifestyle Diseases
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andRole ofHerbal Medicines
AmalKumarDhara andAmitKumarNayak
Abstract
Lifestyle diseases are medical conditions and are primar-
ily caused by unhealthy habits and practices. The differ-
ent risk factors responsible for lifestyle diseases include
poor diet, lack of physical activity, unrestricted alcohol
consumption, smoking and chronic stress, and anxiety.
Commonly occurring lifestyle diseases are type 2 diabe-
tes mellitus, obesity, chronic obstructive pulmonary dis-
ease (COPD), cardiovascular disorders, chronic liver
disease, mental illness, and lung, breast, ovarian, and
colorectal cancers. Lifestyle modication and use of
herbal medicines can help in the management of lifestyle
diseases. The current chapter briey describes the differ-
ent types of lifestyle diseases and their management par-
ticularly the role of herbal medicines.
Keywords
Lifestyle diseases · Management · Herbal medicines
1 Introduction
Lifestyle diseases are medical conditions that predominantly arise from individuals’ everyday habits and behaviors [1, 2]. Certain practices that discourage individuals from engaging in physical activity and instead encourage a sedentary life­style can contribute to various health problems, ultimately leading to chronic non-communicable diseases (NCDs) that may cause signicant risks to one’s life [3, 4]. There are two types of lifestyle factors that are associated with diseases: (1) Modiable factors, such as dietary habits, physical activity
A. K. Dhara (*) Department of Pharmacy, Contai Polytechnic, Government of West Bengal, Contai, West Bengal, India
A. K. Nayak Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India
levels, addictive behaviors (such as smoking and drinking), and stress levels, can be altered or adjusted, and (2) Non­modiable factors, such as age and heredity, gender, ethnic­ity or race are inherently unalterable [58].
The progression of modern civilization has revealed a notable trend wherein an increasing number of young indi­viduals engage in smoking and drinking, despite knowing the detrimental effects these behaviors have on their health [9, 10]. The prevalence of fast food and junk food is displac­ing our nutritious and traditional well-balanced meals, result­ing in a decline in the consumption of fresh fruits and vegetables [11, 12]. Additionally, the preference for pro­cessed and packaged food is supplanting the inclusion of these healthier options. Furthermore, the consumption of soft drinks is increasingly substituting milk intake. Our incli­nation is to utilize transportation, such as buses or cars, rather than engaging in pedestrian travel, even for brief distances [13]. The development of machines to reduce physical labor in the workplace is an increasingly prevalent trend. The aforementioned practices have contributed to the prevalence of overweight and obesity within our population. Obesity refers to the condition of having a body weight that exceeds the normal or ideal weight in relation to an individual’s height [14]. Obesity serves as a primary contributing factor to various lifestyle diseases, including but not limited to dia­betes, hypertension, heart disease, and other related condi­tions [15, 16].
2 Prevention ofLifestyle Diseases
Individuals must modify their behaviors to promote a health­ier lifestyle. Key practices encompass engaging in consistent physical activity such as [17]: (1) walking, practising yoga, participating in dance activities, performing aerobics, and cycling; (2) Utilization of staircases in lieu of lifts or escala­tors; (3) Adhering to a well-rounded dietary regimen during appropriate meal periods; (4) The consumption of processed and packaged foods that are high in sugar, fats, salt, and calo-
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023 A. K. Dhara, S. C. Mandal (eds.), Role of Herbal Medicines, https://doi.org/10.1007/978-981-99-7703-1_1
1
2
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A. K. Dhara and A. K. Nayak
ries, while lacking in ber, high-quality protein, minerals such as iron and calcium, and vitamins, should be mini­mized; (5) It is recommended to consume whole grains such as cereals (wheat, whole wheat our) and millets (sorghum, pearl millet, nger millet, etc.), while minimizing the intake of rened foods; (6) Consuming a daily quantity of 400– 500g of fruits and vegetables in season is recommended; (7) It is recommended to consume an ample amount of water; (8) Implementing yoga or meditation techniques can be ben­ecial in mitigating stress levels in one’s daily existence. (9) It is advisable to refrain from engaging in smoking and con­suming alcohol. It is advisable to reduce the amount of time spent engaging in sedentary activities such as watching television, using mobile phone (WhatsApp, Facebook, Twitter, etc.) and instead prioritize participation in outdoor games and activities, such as gardening or playing sports like football, cricket, or badminton.
3 History ofHerbal Medicine
Ancient Chinese and Egyptian papyrus writings mention the therapeutic applications of plants date back to about 3000 BC, demonstrating that using plants for medicinal purposes predates recorded history. Indigenous cultures, including African and Native American societies, incorpo­rated the utilization of herbs within their healing rituals. In contrast, while other cultures adopted traditional medical systems, such as Ayurveda and Traditional Chinese Medicine, which prominently featured herbal therapies. According to a recent estimation by the World Health Organization, approximately 80% of individuals globally depend on herbal medicines as a component of their pri­mary health care [18, 19]. There has been a signicant rise in the utilization of herbal supplements within the last three decades. In the USA, herbal supplements are catego­rized as dietary supplements.
Scientists worldwide are diligently endeavoring to ascer­tain the mechanisms of action underlying herbal medica­tions [18, 20]. In numerous instances, researchers encounter uncertainty regarding the precise active component within a given herb that contributes to its therapeutic efcacy in addressing a specic medical condition. Whole plants con­sist of numerous components that have the potential to syn­ergistically generate a desirable outcome. Using herbal medicines in scientic contexts is very important due to their potential efcacy in treating diverse conditions [18, 20,
21]. Sometimes using of whole plant may produce lesser
adverse effects than conventional pharmaceutical interven­tions. The assumption that herbs are inherently safe due to their natural origin is not universally valid. Certain medical
conditions may render certain herbs inappropriate for indi­viduals. Due to the absence of regulatory oversight, herbal products frequently exhibit mislabeling tendencies, poten­tially harboring undisclosed additives and contaminants [2224]. Certain herbs have the potential to induce allergic reactions or interact with conventional pharmaceuticals, while others can be toxic when misused or administered in excessive quantities [25, 26]. Engaging in self-medication by consuming herbs independently poses an elevated risk, thus emphasizing the signicance of seeking guidance from a specialist in phytomedicines or a Pharmacist before utili­zation of herbal remedies. An important example of the adverse effects associated with Evening primrose (Oenothera biennis) involves an elevated likelihood of sei- zures in individuals with seizure disorders, as well as an increased risk of bleeding in individuals with bleeding dis­orders or those who are concurrently taking blood-thinning medications, such as warfarin. Numerous herbal substances possess the potential to interact with prescription medica­tions, thereby eliciting undesirable or hazardous reactions [27, 28]. For instance, an exceptional level of herb-drug interaction has been observed in individuals undergoing cancer treatment. Certain herbal supplements, particularly those originating from Asian nations, can potentially con­tain elevated concentrations of heavy metals, such as mer­cury, lead, and cadmium which should be carefully taken into consideration before administration for the treatment of certain disease conditions.
Various herbal preparations can be found in the commer­cial market, encompassing teas, syrups, oils, liquid extracts, tinctures, and dry extracts as pills or capsules [18]. Teas are prepared by steeping dried herbs in hot water for a few min­utes or boiling herbs in water, separating the liquid from the solid components by straining. Syrups, derived from concen­trated extracts and incorporated into sweetened formula­tions, are frequently employed to alleviate sore throats and coughs. Plant-derived oils are commonly extracted and employed as massage rubs, either in their pure form or as constituents of ointments or creams. Tinctures and liquid extracts are bioactive components derived from herbs solubi­lized in a liquid medium, typically water, alcohol, or glyc­erol. Tinctures are commonly prepared with a concentration ratio of 1:5 or 1:10, indicating that one herb unit is combined with ve to ten units (by weight) of the liquid. Liquid extracts are characterized by a higher concentration compared to tinctures, typically exhibiting a 1:1 concentration ratio. The most concentrated form of an herbal product, known as a dry extract, is generally available in the market in the form of tablet, capsule, or lozenge, with a concentration ratio ranging from 2:1 to 8:1. The most commonly used herbs and their uses are mentioned in Table1.