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Interventional Oncology
Principles and Practice of Image-Guided Cancer Therapy
Second Edition
Interventional Oncology
Principles and Practice of Image-Guided Cancer Therapy
Second Edition
Edited by
Chairman of the Department of Radiology and Biomedical Imaging and Professor of Radiology and Oncology, Yale University School of Medicine, New Haven, Connecticut, USA
Michael C. Soulen
Professor of Radiology and Surgery and Director of Interventional Oncology, Abramson Cancer Center, University of Pennsylvania in Philadelphia, Pennsylvania, USA
University Printing House, Cambridge CB2 8BS, United Kingdom
Cambridge University Press is part of the University of Cambridge.
It furthers the University’s mission by disseminating knowledge in the pursuit of education, learning, and research at the highest international levels of excellence.
www.cambridge.org
Information on this title:www.cambridge.org/9781107043473
© Cambridge University Press (2008)2016
is publication is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge UniversityPress.
First published2008
Second edition2016
Printed in the United Kingdom by Clays, St Ives plc
A catalogue record for this publication is available from the British Library
Library of Congress Cataloging in Publicationdata
Names: Geschwind, Jean-François H., 1963– , editor. | Soulen, Michael C., 1958–, editor. Title: Interventional oncology : principles and practice of image-guided cancer therapy / edited by Jean-Francois Geschwind, Michael Soulen. Other titles: Interventional oncology (Geschwind) Description: Second edition. | Cambridge, United Kingdom ; New York : Cambridge University Press, 2016. | Includes bibliographical references and index. Identiers: LCCN 2016011380 | ISBN 9781107043473 (hardback) Subjects: | MESH: Neoplasms – therapy | Neoplasms – diagnosis | erapy, Computer-Assisted – methods Classication: LCC RD651 | NLM QZ 266 | DDC 616.99/4059–dc23 LC record available at http://lccn.loc.gov/2016011380
ISBN 978-1-107-04347-3 Hardback
Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate.
Every eort has been made in preparing this book to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every eort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors, and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. e authors, editors, and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this book. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan touse.
Contents
List of contributors vii
Section I: Principles of oncology
1 Interventional oncology:The fourth pillar of
cancer care 1
Michael C.Soulen and Jean-François H.Geschwind
Section II: Principles of image-guided therapies
2 Principles of radiofrequency and microwave
tumor ablation 3
Anthony M.Esparaz, S.Nahum Goldberg, and MuneebAhmed
3 Principles of irreversible electroporation 13
Govindarajan Srimathveeravalli and Stephen B.Solomon
4 Principles of high-intensity focused ultrasound 20
Aradhana M.Venkatesan and Bradford J.Wood
5 Principles of tumor embolotherapy and
chemoembolization 35
Hwan Jun Jae, Jae Hyung Park, and Jin WookChung
6 Principles of radioembolization 44
Vanessa L.Gates, Riad Salem, and Robert J.Lewandowski
Section III: Organ-specic cancers– primary liver cancers
10 Assessment and triage of hepatocellular
carcinoma 85
Riccardo Lencioni
11 Image-guided ablation of hepatocellular
carcinoma 91
Laura Crocetti, Maria Clotilde Della Pina, Dania Cioni, and Riccardo Lencioni
12 Embolization of liver tumors:Anatomy 100
Hyo-Cheol Kim and Jin WookChung
13 Conventional chemoembolization and
chemoembolization with drug-eluting beads:Technique and future potential 120
Julius Chapiro, Florian Nima Fleckenstein, Lynn Jeanette Savic, and Jean-François H.Geschwind
14 90Yttrium radioembolization for
hepatocellular carcinoma 128
Ryan M.Hickey, Riad Salem, and Robert J.Lewandowski
15 Image-guided therapy of intrahepatic
cholangiocarcinoma 134
Michael C.Soulen and William S.Rilling
7 Principles of intra-arterial infusional
chemotherapy in the treatment of liver metastases from colorectal cancer 52
Fidel David Huitzil Melendez and NancyKemeny
8 Imaging in interventional oncology:Role of
image guidance 65
François Cornelis and Stephen B.Solomon
9 Novel developments in MR assessment of
treatment response after locoregional therapy 77
Kelly Fábrega-Foster, Neda Rastegar, Jean-François H.Geschwind, and Ihab R.Kamel
Section IV: Organ-specic cancers– liver metastases
16 Colorectal masses:Ablation 139
Elena N.Petre, Stephen B.Solomon, and Constantinos T.Sofocleous
17 Assessment, triage, and chemoembolization
for colorectal liver metastases 148
Michael C.Soulen, Govindarajan Narayanan, and Ursina Teitelbaum
v
Contents
18 Radioembolization for colorectal liver
metastases 158
Lourens Bester, Baerbel Meteling, and David Boshell
19 Assessment, triage, and liver-directed
therapies for neuroendocrine tumor metastases 165
Terence P.Gade and Michael C.Soulen
20 Preoperative portal vein embolization 176
David Li and David C.Mado
Section V: Organ-specic cancers– extrahepatic biliary cancer
21 Extrahepatic biliary cancer:Stenting,
brachytherapy, and photodynamic therapy 193
Vlastimil Valek and Tomas Andrasina
Section VI: Organ-specic cancers– renal cell carcinoma
22 Management of small renal masses 203
Mansi A.Saksena, Debra A.Gervais, Michael C.Soulen, and Peter R.Mueller
23 Embolotherapy in the management of renal
cell carcinoma 214
Ricardo Garcia-Monaco
26 Cementoplasty and musculoskeletal
interventions 255
Dimitri Filippiadis, Sean Tutton and Alexis Kelekis
Section IX: Organ-specic cancers– prostate
27 Prostate ablations 265
François Cornelis, Jeremy C.Durack, Behfar Ehdaie, JonathanColeman, and Stephen B.Solomon
Section X: Specialized interventional techniques in cancer care
28 Vascular access:Venous and arterial ports 283
ierry de Baère and Eric Desruennes
29 Palliative care and symptom management 294
Drew A.Rosielle, Melissa Atwood, Sean Marks, and William S.Rilling
30 CT-guided neurolysis for cancer-related
abdominal and pelvic pain 315
Ashrafabet
31 Palliative procedures for ascites and eusion 323
Hooman Yarmohammadi and George I. Getrajdman
Index 333
Section VII: Organ-specic cancers– chest
24 Image-guided ablation in the thorax 223
Erica S.Alexander and Damian E.Dupuy
Section VIII: Organ-specic cancers– musculoskeletal
25 Percutaneous ablation of painful metastases
involving bone 243
Matthew R.Callstrom and A.NicholasKurup
vi
Contributors
Muneeb AhmedMD
Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA,USA
Erica S.AlexanderMD
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA,USA
Tomas AndrasinaMD PhD
Department of Radiology, University Hospital Brno and Medical Faculty, Masaryk University, Brno, Czech Republic
Melissa AtwoodDO
Children’s Hospital of Wisconsin, Milwaukee, WI,USA
Thierry deBaère
Department of Interventional Radiology, Institut de Cancérologie, Villejuif,France
Lourens Bester MBChB BSc(Hons) MMedRad MFGP FRANZCRFACP
Department of Interventional Radiology, University of New South Wales, St. Vincent’s Hospital, Darlinghurst, NSW, Australia
David Boshell MBBS FRANZCR
Department of Interventional Radiology, University of New South Wales, St. Vincent’s Hospital, Darlinghurst, NSW, Australia
Matthew R.CallstromMDPhD
Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN,USA
Julius ChapiroMD
Russell H.Morgan Department of Radiology and Radiological Science, Division of Cardiovascular and Interventional Radiology, Johns Hopkins Hospital, Baltimore, MD,USA
Jin Wook ChungMD
Department of Radiology, Seoul National University Hospital, Seoul,Korea
Dania CioniMD
Division of Diagnostic Imaging and Intervention, Pisa University School of Medicine, Pisa,Italy
Jonathan ColemanMD
Department of Urology, Kimmel Center, Memorial Sloan Kettering Cancer Center, NewYork, NY,USA
François CornelisMDPhD
Department of Radiology, Memorial Sloan Kettering Cancer Center, NewYork, NY,USA
Laura CrocettiMDPhD
Division of Diagnostic Imaging and Intervention, Pisa University School of Medicine, Pisa,Italy
Maria Clotilde Della PinaMDPhD
Division of Diagnostic Imaging and Intervention, Pisa University School of Medicine, Pisa,Italy
Eric Desruennes
Department of Anesthesiology, Institut de Cancérologie, Villejuif,France
Damian E.Dupuy MDFACR
Department of Radiology, Warren Alpert Medical School of Brown University, Providence, RI,USA
Jeremy C.DurackMDMS
Department of Radiology, Memorial Sloan Kettering Cancer Center, NewYork, NY,USA
Behfar EhdaieMD
Department of Urology, Kimmel Center, Memorial Sloan Kettering Cancer Center, NewYork, NY,USA
Anthony M.EsparazMD
Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA,USA
Kelly Fábrega-FosterMD
Russell H.Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD,USA
Dimitri FilippiadisMD PhD
Department of Radiology, School of Medicine, University of Athens, Athens, Greece
vii
Contributors
Florian Nima Fleckenstein
Russell H.Morgan Department of Radiology and Radiological Science, Division of Cardiovascular and Interventional Radiology, Johns Hopkins Hospital, Baltimore, MD,USA
Terence P.GadeMDPhD
Division of Interventional Radiology, University of Pennsylvania, Philadelphia, PA,USA
Ricardo Garcia-Monaco MD PhDFSIR
Department of Radiology, Hospital Italiano, University of Buenos Aires, Argentina
Vanessa L.GatesMS
Department of Radiology, Section of Interventional Oncology, Northwestern University, Robert H.Lurie Comprehensive Cancer Center, Chicago, IL,USA
Debra A.GervaisMD
Massachusetts General Hospital, Boston, MA,USA
Jean-François H.GeschwindMD
Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, CT,USA
George I. Getrajdman MD
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Riccardo Lencioni MD FSIREBIR
Department of Radiology, University of Pisa School of Medicine, Pisa,Italy
Robert J.LewandowskiMD
Department of Radiology, Section of Interventional Oncology, Northwestern University, Robert H.Lurie Comprehensive Cancer Center, Chicago, IL,USA
David LiMDPhD
Department of Radiology, Weill Cornell Medical College, NewYork, NY,USA
David C.Mado
Department of Radiology, Weill Cornell Medical College, NewYork, NY,USA
Sean MarksMD
Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI,USA
Fidel David Huitzil MelendezMDMSc
Memorial Sloan Kettering Cancer Center, NewYork, NY,USA
Baerbel Meteling BvetMedPhD
Department of Interventional Radiology, University of New South Wales, St. Vincent’s Hospital, Darlinghurst, NSW, Australia
S. Nahum GoldbergMD
Interventional Oncology Unit, Department of Radiology, Hadassah Hebrew University Medical Center, Ein Karem, Jerusalem,Israel
Ryan M.HickeyMD
Northwestern University, Chicago, IL,USA
Hwan JunJaeMD
Department of Radiology, Seoul National University Hospital, Seoul,Korea
Ihab R.KamelMDPhD
Russell H.Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD,USA
Alexis KelekisMD EBIR FSIR
2nd Department of Radiology, School of Medicine, National and Kapodistrian University of Athens,
Athens,Greece
Nancy KemenyMD
Medical Oncologist, Memorial Sloan Kettering Cancer Center, NewYork, NY,USA
Hyo-CheolKimMD
Department of Radiology, Seoul National University Hospital, Seoul,Korea
A. Nicholas KurupMD
Mayo Clinic College of Medicine, Rochester, MN,USA
Peter R.Mueller MD FSIRFCIRSE
Department of Radiology, Harvard Medical School, Boston, MA,USA
Govindarajan Narayanan MDFSIR
University of Miami, Coral Gables, FL,USA
Jae Hyung ParkMD
Department of Radiology, Gachon University Gil Medical Center, Incheon,Korea
Elena N.Petre
Department of Radiology, Section of Interventional Radiology, Memorial Sloan Kettering Cancer Center, NewYork, NY,USA
Neda RastegarMD
Russell H.Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD,USA
William S.Rilling MDFSIR
Department of Radiology, Medical College of Wisconsin, Milwaukee, WI,USA
Drew A.RosielleMD
Palliative Medicine, University of Minnesota Medical Center, Minneapolis, MN,USA
Mansi A.SaksenaMBBS
Department of Radiology, Massachusetts General Hospital, Boston, MA,USA
viii