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- •2 Principles of radiofrequency and microwave tumor ablation
- •Cooling in microwave ablation
- •Pulsed RF application
- •Operator and technique
- •Choice of applicator
- •Overlapping techniques
- •Introduction
- •Biology of heating
- •Radiofrequency ablation
- •Microwave ablation
- •Energy-deposited technology
- •Multitine applicators
- •Internally cooled electrodes
- •Perfused electrodes
- •Ancillary procedures
- •Combination therapies
- •Combining RF with transarterial chemoembolization
- •Combining RF with chemotherapy
- •Combining RF ablation with radiation
- •Patient selection
- •Conclusion
- •References
- •3 Principles of irreversible electroporation
- •Introduction
- •Numerical simulations
- •Clinical considerations
- •Clinical experience
- •Conclusion
- •References
- •4 Principles of high-intensity focused ultrasound
- •Introduction
- •History
- •Ablation
- •Hyperthermia
- •Thermal dose concept
- •Cavitation
- •Histotripsy
- •Microstreaming
- •HIFU system technology
- •Ultrasound guidance
- •MRI guidance
- •HIFU devices
- •Clinical applications
- •Prostate
- •Breast
- •Liver
- •Bone
- •Emerging applications
- •Targeted drug delivery
- •Blood–brain barrier disruption
- •Conclusion
- •References
- •5 Principles of tumor embolotherapy and chemoembolization
- •Tumor embolotherapy
- •General indications
- •Embolic materials
- •Gelfoam
- •Coils
- •Absolute ethanol
- •Microspheres
- •Pre-embolization evaluation
- •Roadmap and superselective arteriography
- •Chemoembolization
- •Basic principle
- •Chemotherapeutic agents used for chemoembolization
- •Lipiodol chemoembolization
- •Subsegmental chemoembolization
- •Drug-eluting bead TACE (DEB-TACE)
- •References
- •6 Principles of radioembolization
- •Introduction
- •Mechanism of radioembolization
- •Radioembolic material
- •Indications and contraindications
- •Imaging considerations
- •Base and follow-up cross-sectional imaging
- •Localization imaging (nuclear medicine imaging)
- •Determining treatment dosage (activity)
- •(Y-90) SIR-Sphere
- •(Y-90) TheraSphere
- •Microcatheters
- •(Y-90) SIR-Sphere
- •(Y-90) TheraSphere
- •Radiation safety considerations
- •Patient release
- •Radiation safety considerations for cases involving surgery
- •Radiation safety considerations in case of autopsy, burial, or cremation
- •References
- •Background
- •Regional delivery of the drug leads to increased local concentration
- •Increased local concentration leads to increased therapeutic response
- •Regional delivery of a drug leads to decreased systemic exposure
- •5-Fluorouracil
- •Irinotecan
- •Oxaliplatin
- •Hepatic artery combination chemotherapy administration
- •Hepatic intra-arterial infusion of irinotecan-loaded drug-eluting beads (DEBIRI)
- •Therapeutic monoclonal antibodies
- •Future research
- •Regional therapy pharmacology appendix
- •Pharmacology appendix
- •References
- •Introduction
- •Imaging for procedure planning
- •Imaging for device delivery
- •Advances in real-time imaging
- •Three-dimensionality
- •Navigation
- •Robotics
- •Combining best systemic chemotherapy with best HAI strategy
- •Open access to the patient
- •Radiation exposure
- •Intraprocedural monitoring
- •Imaging for therapy assessment
- •Summary
- •References
- •9 Novel developments in MR assessment of treatment response after locoregional therapy
- •Anatomic biomarkers
- •The volumetric approach
- •Conclusion
- •References
- •10 Assessment and triage of hepatocellular carcinoma
- •Summary
- •Introduction
- •Assessment of hepatocellular carcinoma
- •Diagnostic criteria
- •Clinical staging
- •Triage of hepatocellular carcinoma
- •Liver transplantation
- •Surgical resection
- •Image-guided ablation
- •Transarterial treatment
- •Systemic treatment
- •Conclusion
- •References
- •11 Image-guided ablation of hepatocellular carcinoma
- •Introduction
- •Very-early-stage hepatocellular carcinoma
- •Early-stage hepatocellular carcinoma
- •Conclusion
- •References
- •Celiac trunk anatomy
- •Normal celiac trunk anatomy and variations
- •Celiac stenosis or occlusion
- •Hepatic artery anatomy
- •Intrahepatic variations in branching segmental hepatic arteries
- •Non-hepatic arteries arising from hepatic arteries
- •Pancreaticoduodenal arteries
- •Extrahepatic collateral arteries
- •Anatomy of extrahepatic collateral arteries
- •Inferior phrenic arteries
- •Internal mammary arteries
- •Intercostal and lumbar arteries
- •Omental arteries
- •Adrenal arteries
- •Renal and renal capsular arteries
- •Gastric arteries
- •Colic branches
- •Transcatheter management of extrahepatic collateral arteries
- •References
- •Background
- •Patient selection and contraindications for TACE and DEB-TACE
- •Technique
- •Follow-up and evaluation of response to treatment
- •Clinical outcome
- •Combination therapies
- •Conclusion and outlook
- •References
- •Patient selection
- •Technique
- •Dosimetry
- •Adverse events and toxicities
- •Clinical outcomes
- •References
- •15 Image-guided therapy of intrahepatic cholangiocarcinoma
- •Curative therapies
- •Percutaneous ablation
- •Non-curative therapies
- •Chemoembolization
- •Radioembolization
- •Multidisciplinary approach
- •References
- •Introduction
- •Indications
- •Contraindications
- •Ablation modalities
- •Radiofrequency ablation
- •Cryoablation
- •Microwave ablation
- •Irreversible electroporation
- •Laser-induced interstitial thermotherapy
- •Discussion
- •References
- •17 Assessment, triage, and chemoembolization for colorectal liver metastases
- •Assessment of the patient with liver metastases
- •Triage of patients with liver metastases
- •Resection
- •Ablation
- •Intra-arterial chemoinfusion
- •Systemic therapy
- •Chemoembolization
- •Patient selection for chemoembolization
- •Chemoembolization regimens
- •“Conventional” cocktails
- •Drug-eluting microsphere platforms
- •Technical aspects of chemoembolization
- •Loading
- •Technique for drug-eluting microsphere embolization
- •Delivery endpoints
- •Outcomes with drug-eluting microspheres
- •Summary
- •References
- •18 Radioembolization for colorectal liver metastases
- •Introduction
- •Patient presentation
- •Preimplantation workup procedure
- •Treatment process
- •Dosimetry and dose calculation
- •TheraSphere
- •SIR-Spheres
- •Postprocedural care and follow-up
- •Postprocedure considerations
- •Postembolization syndrome (20–30%)
- •CT/PET evaluation of tumor response
- •Radioembolization combined with second- or third-line chemotherapy
- •Conclusion
- •References
- •19 Assessment, triage, and liver-directed therapies for neuroendocrine tumor metastases
- •Terminology
- •Demographics and epidemiology
- •Diagnosis
- •Prognosis
- •Multidisciplinary triage of neuroendocrine neoplasms
- •Systemic therapies
- •Surgical management
- •Image-guided therapy
- •Tumor ablation
- •Hepatic arterial therapy
- •Conclusion
- •References
- •20 Preoperative portal vein embolization
- •Mechanisms of liver regeneration
- •Rate of liver regeneration
- •Standard approaches
- •Additional approaches
- •PVE in conjunction with transarterial therapies
- •Extent of embolization
- •Embolic materials
- •Complications
- •General indications
- •General contraindications
- •Underlying liver disease
- •High-dose chemotherapy
- •Conclusion
- •References
- •Photodynamic therapy
- •Radiotherapy
- •References
- •Clinical overview
- •Staging
- •Diagnosis
- •Treatment options
- •Surgery
- •Percutaneous techniques
- •Radiofrequency ablation
- •Background
- •Histology of RFA
- •Microwave ablation
- •Background
- •Histology
- •Cryoablation
- •Background
- •Histology of cryoablation
- •Indications for percutaneous ablation
- •Patient factors
- •Preablation imaging
- •Adjunctive procedures
- •Technique
- •Anesthesia
- •Modality for guidance
- •Radiofrequency ablation
- •Microwave ablation
- •Cryoablation
- •Adjacent structures
- •Postprocedure follow-up
- •Complications
- •Treatment of metastatic disease
- •Surgical and RFA options
- •Medical therapies
- •Conclusion
- •References
- •23 Embolotherapy in the management of renal cell carcinoma
- •Introduction
- •Basic concepts
- •Embolization technique
- •Preoperative embolization
- •Radical nephrectomy
- •Partial nephrectomy
- •Postoperative embolization
- •Palliative embolization
- •Complications
- •Conclusion
- •References
- •Physics of ablation therapy
- •Radiofrequency ablation
- •Microwave ablation
- •Cryoablation
- •Irreversible electroporation
- •Performing ablation therapy
- •Patient selection
- •Procedure
- •Radiofrequency ablation
- •Microwave ablation
- •Cryoablation
- •Irreversible electroporation
- •Imaging follow-up
- •Radiofrequency ablation
- •Microwave ablation
- •Cryoablation
- •Irreversible electroporation
- •Comparison of thermal ablation techniques
- •Applications and outcomes for thoracic ablation
- •Palliation
- •Conclusion
- •References
- •Introduction
- •Indications for treatment
- •Preprocedural imaging
- •Contraindications to ablation treatment
- •RFA technique
- •RFA pain palliation outcomes
- •Cryoablation technique
- •Cryoablation pain palliation outcomes
- •Emerging technologies
- •Summary
- •References
- •26 Cementoplasty and musculoskeletal interventions
- •Introduction
- •Indications
- •Contraindications
- •Technique
- •Postprocedural care and follow-up
- •Current bone cement properties and future directions
- •Percutaneous sacroplasty, osteoplasty, and advance hybrid stabilization techniques
- •Summary
- •References
- •27 Prostate ablations
- •Introduction
- •Patient selection
- •Cancer detection and treatment guidance
- •Patient selection
- •Targeting strategies
- •Image guidance for prostate ablation
- •Ultrasound guidance
- •MR guidance
- •Computed tomography guidance
- •Positron emission tomography guidance
- •Prostate ablation techniques
- •High-intensity focused ultrasound
- •Cryoablation
- •Other techniques
- •Postprocedure evaluation
- •Complications and outcomes
- •Local control
- •Conclusion
- •Acknowledgments
- •References
- •Indications
- •Rationale
- •Technique
- •Catheter positioning
- •Contraindications
- •Results
- •Port/catheter placement
- •Chemotherapy
- •Description
- •Indications
- •Preoperative assessment
- •Catheter tip location
- •Update on vein thrombosis prophylaxis and treatment
- •Catheter-related infection
- •References
- •29 Palliative care and symptom management
- •Palliative care and communication with cancer patients
- •Communication with cancer patients
- •Prognostication
- •Medical symptom management
- •Pain
- •Non-opioid analgesics
- •Opioid analgesics
- •Adjuvant analgesics
- •Bone metastases
- •Nausea and vomiting
- •Constipation
- •Constitutional symptoms
- •Ascites
- •Psychiatric symptoms
- •Depression
- •Anxiety
- •Summary
- •References
- •Introduction
- •Celiac plexus neurolysis
- •Anatomy
- •Technique
- •Positioning and approach
- •Antecrural
- •Retrocrural
- •Outcomes
- •Complications
- •Superior hypogastric neurolysis
- •Anatomy
- •Technique
- •Positioning and approach
- •Outcomes
- •Complications
- •Ganglion impar neurolysis
- •Anatomy
- •Technique
- •Outcomes
- •Complications
- •References
- •Introduction
- •Management of ascites
- •Diuretics and sodium restriction
- •Large-volume paracentesis
- •Permanent indwelling catheters
- •Pigtail or Cope-type loop catheter
- •PleurX and Asept catheters
- •Peritoneal Port-A-Catheters
- •Thoracentesis
- •Chest drainage catheters
- •Pigtail catheters
- •Tunneled catheters
- •Summary of recommendations and guidelines
- •References
- •Index



Interventional Oncology
Principles and Practice of Image-Guided Cancer Therapy
Second Edition


Interventional Oncology
Principles and Practice of Image-Guided Cancer Therapy
Second Edition
Edited by
Jean-François H. Geschwind
Chairman of the Department of Radiology and Biomedical Imaging and Professor of Radiology and Oncology,
Yale University School of Medicine, New Haven, Connecticut, USA
Michael C. Soulen
Professor of Radiology and Surgery and Director of Interventional Oncology, Abramson Cancer Center,
University of Pennsylvania in Philadelphia, Pennsylvania, USA

University Printing House, Cambridge CB2 8BS, United Kingdom
Cambridge University Press is part of the University of Cambridge.
It furthers the University’s mission by disseminating knowledge in the pursuit of
education, learning, and research at the highest international levels of excellence.
www.cambridge.org
Information on this title:www.cambridge.org/9781107043473
© Cambridge University Press (2008)2016
is publication is in copyright. Subject to statutory exception
and to the provisions of relevant collective licensing agreements,
no reproduction of any part may take place without the written
permission of Cambridge UniversityPress.
First published2008
Second edition2016
Printed in the United Kingdom by Clays, St Ives plc
A catalogue record for this publication is available from the British Library
Library of Congress Cataloging in Publicationdata
Names: Geschwind, Jean-François H., 1963– , editor. | Soulen, Michael C., 1958–, editor.
Title: Interventional oncology : principles and practice of image-guided cancer therapy /
edited by Jean-Francois Geschwind, Michael Soulen.
Other titles: Interventional oncology (Geschwind)
Description: Second edition. | Cambridge, United Kingdom ; New York : Cambridge
University Press, 2016. | Includes bibliographical references and index.
Identiers: LCCN 2016011380 | ISBN 9781107043473 (hardback)
Subjects: | MESH: Neoplasms – therapy | Neoplasms – diagnosis |
erapy, Computer-Assisted – methods
Classication: LCC RD651 | NLM QZ 266 | DDC 616.99/4059–dc23
LC record available at http://lccn.loc.gov/2016011380
ISBN 978-1-107-04347-3 Hardback
Cambridge University Press has no responsibility for the persistence or accuracy
of URLs for external or third-party internet websites referred to in this publication,
and does not guarantee that any content on such websites is, or will remain,
accurate or appropriate.
Every eort has been made in preparing this book to provide accurate and up-to-date information which
is in accord with accepted standards and practice at the time of publication. Although case histories are
drawn from actual cases, every eort has been made to disguise the identities of the individuals involved.
Nevertheless, the authors, editors, and publishers can make no warranties that the information contained
herein is totally free from error, not least because clinical standards are constantly changing through
research and regulation. e authors, editors, and publishers therefore disclaim all liability for direct or
consequential damages resulting from the use of material contained in this book. Readers are strongly
advised to pay careful attention to information provided by the manufacturer of any drugs or equipment
that they plan touse.

Contents
List of contributors vii
Section I: Principles of oncology
1 Interventional oncology:The fourth pillar of
cancer care 1
Michael C.Soulen and Jean-François H.Geschwind
Section II: Principles of image-guided
therapies
2 Principles of radiofrequency and microwave
tumor ablation 3
Anthony M.Esparaz, S.Nahum Goldberg, and
MuneebAhmed
3 Principles of irreversible electroporation 13
Govindarajan Srimathveeravalli and
Stephen B.Solomon
4 Principles of high-intensity focused ultrasound 20
Aradhana M.Venkatesan and Bradford J.Wood
5 Principles of tumor embolotherapy and
chemoembolization 35
Hwan Jun Jae, Jae Hyung Park, and Jin WookChung
6 Principles of radioembolization 44
Vanessa L.Gates, Riad Salem, and Robert J.Lewandowski
Section III: Organ-specic cancers– primary
liver cancers
10 Assessment and triage of hepatocellular
carcinoma 85
Riccardo Lencioni
11 Image-guided ablation of hepatocellular
carcinoma 91
Laura Crocetti, Maria Clotilde Della Pina, Dania Cioni,
and Riccardo Lencioni
12 Embolization of liver tumors:Anatomy 100
Hyo-Cheol Kim and Jin WookChung
13 Conventional chemoembolization and
chemoembolization with drug-eluting
beads:Technique and future potential 120
Julius Chapiro, Florian Nima Fleckenstein, Lynn Jeanette
Savic, and Jean-François H.Geschwind
14 90Yttrium radioembolization for
hepatocellular carcinoma 128
Ryan M.Hickey, Riad Salem, and Robert J.Lewandowski
15 Image-guided therapy of intrahepatic
cholangiocarcinoma 134
Michael C.Soulen and William S.Rilling
7 Principles of intra-arterial infusional
chemotherapy in the treatment of liver
metastases from colorectal cancer 52
Fidel David Huitzil Melendez and NancyKemeny
8 Imaging in interventional oncology:Role of
image guidance 65
François Cornelis and Stephen B.Solomon
9 Novel developments in MR assessment of
treatment response after locoregional therapy 77
Kelly Fábrega-Foster, Neda Rastegar, Jean-François
H.Geschwind, and Ihab R.Kamel
Section IV: Organ-specic cancers– liver
metastases
16 Colorectal masses:Ablation 139
Elena N.Petre, Stephen B.Solomon, and Constantinos
T.Sofocleous
17 Assessment, triage, and chemoembolization
for colorectal liver metastases 148
Michael C.Soulen, Govindarajan Narayanan, and Ursina
Teitelbaum
v

Contents
18 Radioembolization for colorectal liver
metastases 158
Lourens Bester, Baerbel Meteling, and David Boshell
19 Assessment, triage, and liver-directed
therapies for neuroendocrine tumor
metastases 165
Terence P.Gade and Michael C.Soulen
20 Preoperative portal vein embolization 176
David Li and David C.Mado
Section V: Organ-specic cancers– extrahepatic
biliary cancer
21 Extrahepatic biliary cancer:Stenting,
brachytherapy, and photodynamic therapy 193
Vlastimil Valek and Tomas Andrasina
Section VI: Organ-specic cancers– renal
cell carcinoma
22 Management of small renal masses 203
Mansi A.Saksena, Debra A.Gervais, Michael C.Soulen,
and Peter R.Mueller
23 Embolotherapy in the management of renal
cell carcinoma 214
Ricardo Garcia-Monaco
26 Cementoplasty and musculoskeletal
interventions 255
Dimitri Filippiadis, Sean Tutton and Alexis Kelekis
Section IX: Organ-specic cancers– prostate
27 Prostate ablations 265
François Cornelis, Jeremy C.Durack, Behfar Ehdaie,
JonathanColeman, and Stephen B.Solomon
Section X: Specialized interventional techniques
in cancer care
28 Vascular access:Venous and arterial ports 283
ierry de Baère and Eric Desruennes
29 Palliative care and symptom management 294
Drew A.Rosielle, Melissa Atwood, Sean Marks, and
William S.Rilling
30 CT-guided neurolysis for cancer-related
abdominal and pelvic pain 315
Ashrafabet
31 Palliative procedures for ascites and eusion 323
Hooman Yarmohammadi and George I. Getrajdman
Index 333
Section VII: Organ-specic
cancers– chest
24 Image-guided ablation in the thorax 223
Erica S.Alexander and Damian E.Dupuy
Section VIII: Organ-specic
cancers– musculoskeletal
25 Percutaneous ablation of painful metastases
involving bone 243
Matthew R.Callstrom and A.NicholasKurup
vi

Contributors
Muneeb AhmedMD
Department of Radiology, Beth Israel Deaconess Medical
Center, Boston, MA,USA
Erica S.AlexanderMD
Department of Radiology, Hospital of the University of
Pennsylvania, Philadelphia, PA,USA
Tomas AndrasinaMD PhD
Department of Radiology, University Hospital Brno and
Medical Faculty, Masaryk University, Brno, Czech Republic
Melissa AtwoodDO
Children’s Hospital of Wisconsin, Milwaukee, WI,USA
Thierry deBaère
Department of Interventional Radiology, Institut de
Cancérologie, Villejuif,France
Lourens Bester MBChB BSc(Hons) MMedRad MFGP
FRANZCRFACP
Department of Interventional Radiology, University of
New South Wales, St. Vincent’s Hospital, Darlinghurst,
NSW, Australia
David Boshell MBBS FRANZCR
Department of Interventional Radiology, University of
New South Wales, St. Vincent’s Hospital, Darlinghurst,
NSW, Australia
Matthew R.CallstromMDPhD
Department of Radiology, Mayo Clinic College of Medicine,
Rochester, MN,USA
Julius ChapiroMD
Russell H.Morgan Department of Radiology and Radiological
Science, Division of Cardiovascular and Interventional
Radiology, Johns Hopkins Hospital, Baltimore, MD,USA
Jin Wook ChungMD
Department of Radiology, Seoul National University Hospital,
Seoul,Korea
Dania CioniMD
Division of Diagnostic Imaging and Intervention, Pisa
University School of Medicine, Pisa,Italy
Jonathan ColemanMD
Department of Urology, Kimmel Center, Memorial Sloan
Kettering Cancer Center, NewYork, NY,USA
François CornelisMDPhD
Department of Radiology, Memorial Sloan Kettering Cancer
Center, NewYork, NY,USA
Laura CrocettiMDPhD
Division of Diagnostic Imaging and Intervention, Pisa
University School of Medicine, Pisa,Italy
Maria Clotilde Della PinaMDPhD
Division of Diagnostic Imaging and Intervention, Pisa
University School of Medicine, Pisa,Italy
Eric Desruennes
Department of Anesthesiology, Institut de Cancérologie,
Villejuif,France
Damian E.Dupuy MDFACR
Department of Radiology, Warren Alpert Medical School of
Brown University, Providence, RI,USA
Jeremy C.DurackMDMS
Department of Radiology, Memorial Sloan Kettering Cancer
Center, NewYork, NY,USA
Behfar EhdaieMD
Department of Urology, Kimmel Center,
Memorial Sloan Kettering Cancer Center,
NewYork, NY,USA
Anthony M.EsparazMD
Department of Radiology, Beth Israel Deaconess Medical
Center, Boston, MA,USA
Kelly Fábrega-FosterMD
Russell H.Morgan Department of Radiology and
Radiological Sciences, Johns Hopkins University,
Baltimore, MD,USA
Dimitri FilippiadisMD PhD
Department of Radiology, School of Medicine,
University of Athens,
Athens, Greece
vii

Contributors
Florian Nima Fleckenstein
Russell H.Morgan Department of Radiology and Radiological
Science, Division of Cardiovascular and Interventional
Radiology, Johns Hopkins Hospital, Baltimore, MD,USA
Terence P.GadeMDPhD
Division of Interventional Radiology, University of
Pennsylvania, Philadelphia, PA,USA
Ricardo Garcia-Monaco MD PhDFSIR
Department of Radiology, Hospital Italiano, University of
Buenos Aires, Argentina
Vanessa L.GatesMS
Department of Radiology, Section of Interventional Oncology,
Northwestern University, Robert H.Lurie Comprehensive
Cancer Center, Chicago, IL,USA
Debra A.GervaisMD
Massachusetts General Hospital, Boston, MA,USA
Jean-François H.GeschwindMD
Department of Radiology and Biomedical Imaging,
Yale University School of Medicine, New Haven,
CT,USA
George I. Getrajdman MD
Department of Radiology, Memorial Sloan Kettering Cancer
Center, New York, NY, USA
Riccardo Lencioni MD FSIREBIR
Department of Radiology, University of Pisa School of
Medicine, Pisa,Italy
Robert J.LewandowskiMD
Department of Radiology, Section of Interventional Oncology,
Northwestern University, Robert H.Lurie Comprehensive
Cancer Center, Chicago, IL,USA
David LiMDPhD
Department of Radiology, Weill Cornell Medical College,
NewYork, NY,USA
David C.Mado
Department of Radiology, Weill Cornell Medical College,
NewYork, NY,USA
Sean MarksMD
Division of Hematology and Oncology, Medical College of
Wisconsin, Milwaukee, WI,USA
Fidel David Huitzil MelendezMDMSc
Memorial Sloan Kettering Cancer Center,
NewYork, NY,USA
Baerbel Meteling BvetMedPhD
Department of Interventional Radiology, University of New
South Wales, St. Vincent’s Hospital, Darlinghurst,
NSW, Australia
S. Nahum GoldbergMD
Interventional Oncology Unit, Department of Radiology,
Hadassah Hebrew University Medical Center, Ein Karem,
Jerusalem,Israel
Ryan M.HickeyMD
Northwestern University, Chicago, IL,USA
Hwan JunJaeMD
Department of Radiology, Seoul National University Hospital,
Seoul,Korea
Ihab R.KamelMDPhD
Russell H.Morgan Department of Radiology and
Radiological Sciences, Johns Hopkins University,
Baltimore, MD,USA
Alexis KelekisMD EBIR FSIR
2nd Department of Radiology, School of Medicine,
National and Kapodistrian University of Athens,
Athens,Greece
Nancy KemenyMD
Medical Oncologist, Memorial Sloan Kettering Cancer Center,
NewYork, NY,USA
Hyo-CheolKimMD
Department of Radiology, Seoul National University Hospital,
Seoul,Korea
A. Nicholas KurupMD
Mayo Clinic College of Medicine, Rochester, MN,USA
Peter R.Mueller MD FSIRFCIRSE
Department of Radiology, Harvard Medical School, Boston,
MA,USA
Govindarajan Narayanan MDFSIR
University of Miami, Coral Gables, FL,USA
Jae Hyung ParkMD
Department of Radiology, Gachon University Gil Medical
Center, Incheon,Korea
Elena N.Petre
Department of Radiology, Section of Interventional
Radiology, Memorial Sloan Kettering Cancer Center,
NewYork, NY,USA
Neda RastegarMD
Russell H.Morgan Department of Radiology and
Radiological Sciences, Johns Hopkins University,
Baltimore, MD,USA
William S.Rilling MDFSIR
Department of Radiology, Medical College of Wisconsin,
Milwaukee, WI,USA
Drew A.RosielleMD
Palliative Medicine, University of Minnesota Medical Center,
Minneapolis, MN,USA
Mansi A.SaksenaMBBS
Department of Radiology, Massachusetts General Hospital,
Boston, MA,USA
viii
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